Biomedical data science

Biomedical data science

Biomedical data science is a multidisciplinary field which leverages large volumes of data to promote biomedical innovation and discovery. Biomedical data science draws from various fields including Biostatistics, Biomedical informatics, and machine learning, with the goal of understanding biological and medical data. It can be viewed as the study and application of data science to solve biomedical problems. Modern biomedical datasets often have specific features which make their analyses difficult, including: Large numbers of feature (sometimes billions), typically far larger than the number of samples (typically tens or hundreds) Noisy and missing data Privacy concerns (e.g., electronic health record confidentiality) Requirement of interpretability from decision makers and regulatory bodies Many biomedical data science projects apply machine learning to such datasets. These characteristics, while also present in many data science applications more generally, make biomedical data science a specific field. Examples of biomedical data science research include: Computational genomics Computational imaging Electronic health records data mining Biomedical network science Clinical Natural Language Processing (NLP) == Computational Imaging and Deep Learning == Computational imaging is a cornerstone of biomedical data science, focusing on the development of algorithms to enhance, analyze, and interpret medical imagery. In recent years, the field has been transformed by the integration of deep learning, particularly through the use of Convolutional Neural Networks. Deep learning started from researchers manually defining characteristics like edge detection or texture representation learning. In a more modern approach of computational imaging, models automatically learn a hierarchy of features directly from raw pixel data. This overlap between data science and deep learning is applied across several key tasks: Classification: Identifying the presence of specific diseases, such as distinguishing between benign and malignant tumors in histopathology slides or detecting pneumonia in chest X-rays. Segmentation: The precise delineation of anatomical structures or lesions. A notable example is the U-Net architecture, which is widely used for biomedical image segmentation to help clinicians quantify organ volume or track tumor growth. Detection: Automating the localization of small objects, such as identifying microcalcifications in mammograms or polyps during colonoscopies. Registration: The process of aligning multiple images to provide a comprehensive view of the patient's anatomy. Even with all of these enhancements, the application of deep learning in medical imaging requires accomplishing vigorous challenges. An example of these changes is building large, annotated datasets and creating the imperative for model interpretability in clinical decision-making. == Electronic Health Records == Electronic Health Records (EHRs) are a digital alternative to patient paper charts, usually including individual records or population health information. EHRs can be used in a wide variety of applications, including research and analysation as they often include demographics, diagnoses, medications, test results, and personal statistics. === History === ==== 1960s ==== The earliest precursor is considered Dr. Lawrence Weed's problem-oriented medical record (POMR) published in the 1968 which sorts and groups medical records by medical diagnoses and symptoms. The POMR was the first system to organize based off of patient information rather than the source (doctors, nurses, attendings, etc.). In 1969, the Regenstrief Institute developed and published the Regenstrief Medical Record System which established electronic writing, storage, and retrieval of records which served as the basis for modern EHR systems. ==== 2000s ==== In 2009, the Health Information Technology for Economic and Clinical Health Act (HITECH Act) was passed in the United States. This act standardized privacy and distribution of EHRs and increased the acceptance and utilization of EHRs within medical and academic settings. == Artificial Intelligence and Machine Learning Applications == Machine Learning and Artificial Intelligence have become central tools in biomedical data science. Recent advances in large language models (LLMs) have expanded their role beyond text, with models trained directly on genomic sequences enabling tasks such as gene function prediction, variant effect analysis, and drug discovery. In clinical settings, Natural Language Processing (NLP) models are applied to electronic health records to extract structured insights from unstructured clinical notes and data, supporting diagnosis and treatment planning. Beyond genomics, AI models have been applied to protein structure prediction. AlphaFold, developed by Google DeepMind, uses deep learning to predict three-dimensional protein structures from amino acid sequences with high accuracy. These predictions have been used to support drug target identification and the study of disease mechanisms. == Knowledge Graphs == Knowledge graphs (KGs) are widely used in biomedical data science to represent and analyze complex relationships among biological and medical entities. By structuring data as nodes (e.g., genes, diseases, drugs) and edges (relationships), KGs enable computational methods to extract insights and support decision-making. These biomedical relationships can be efficiently modeled and queried using technologies such as Neo4j. === Biomedical Research Applications === KGs provide biomedical researchers with a way to model complex biological systems. They have been used to identify the relationships between diseases and biomolecules, support drug repurposing, and to uncover new biological insights. Additional applications include: Identification of novel antibiotic resistance genes through graph-based link prediction. Finding associations between miRNA and diseases. Prediction of protein-protein interactions. === Clinical Applications === In clinical settings, KGs can be used to make visual representations of a patient's electronic health records. The data obtained from these graphs can assist healthcare providers in improving patient diagnoses and prescribing more effective drugs. Additionally, embeddings derived from resources like the Unified Medical Language System (UMLS) enable natural language processing of clinical text and similarity analysis between medical concepts. === Limitations === Despite their advantages, knowledge graphs face several challenges. Some of these include: High algorithmic complexity and large biological datasets make the process computationally expensive. KG construction can be a time-consuming process that requires careful attention to assign appropriate node types and vocabularies. Using data from a wide range of datasets in one KG requires them to be effectively integrated. == Privacy == A primary challenge in biomedical data science is maintaining medical privacy. Conducting research requires that data be collected on a number of people for training and testing purposes and is stored within biomedical datasets. This poses a risk for violating patient confidentiality and may dissuade people from participating in studies. The main sources of health statistics are surveys administrative and medical records health care claims data, vital records surveillance disease registries grey literature and peer-reviewed literature. Large data collection is a useful tool for researching various medical conditions. Researchers use these large datasets of information to identify factors that may make people more susceptible to certain diseases. Large amounts of collected data can help researchers identify patterns for disease probabilities. The findings can show a person is more likely for a condition, or identify environmental, social, and personal habits that may lead to adverse health issues. Institutions researching using personal medical information come with a moral and legal responsibility to protect the use of that information. Protection of the collected information has become a big concern. Sophisticated and coordinated attacks on certain medical systems happen more frequently. Medical companies, medical insurance and private businesses have invested a great deal into the protection of personal data. Despite this, data breaches continue to be documented. The chart below shows the top healthcare breaches in 2025. For these reasons, many people have reservations about giving up their personal data. Aside from the legitimate use of personal data there have been instances where companies have found methods to profit from brokering medical information. Concerns exist regarding unauthorized use of sensitive information within these data companies. If a person is identified within a dataset, then sensitive data can be used to discriminate against them. For example, insurance companies may charge a hi

Facial age estimation

Facial age estimation is the use of artificial intelligence to estimate the age of a person based on their facial features. Computer vision techniques are used to analyse the facial features in the images of millions of people whose age is known and then deep learning is used to create an algorithm that tries to predict the age of an unknown person. The key use of the technology is to prevent access to age-restricted goods and services. Examples include restricting children from accessing internet pornography, checking that they meet a mandatory minimum age when registering for an account on social media, or preventing adults from accessing websites, online chat or games designed only for use by children. The technology is distinct from facial recognition systems as the software does not attempt to uniquely identify the individual. Researchers have applied neural networks for age estimation since at least 2010. == Evaluation == An ongoing study by the National Institute of Standards and Technology (NIST) entitled 'Face Analysis Technology Evaluation' seeks to establish the technical performance of prototype age estimation algorithms submitted by academic teams and software vendors including Brno University of Technology, Czech Technical University in Prague, Dermalog, IDEMIA, Incode Technologies Inc, Jumio, Nominder, Rank One Computing, Unissey and Yoti. == Public sector use == The UK government has explored using facial age estimation at the UK border as an alternative to bone X-rays and MRI scans when determining child status of asylum seekers. == Commercial use == Commercial users of facial age estimation include Instagram and OnlyFans. In January 2025, John Lewis & Partners announced that had started using the technology to check the age of people shopping for knives on its website, to comply with UK legislation to limit knife crime. In the UK, several supermarket chains have taken part in Home Office trials of the technology to automate the checking of a customer's age when buying age-restricted goods such as alcohol. UK legislation introduced in January 2025 mandates robust forms of age verification hosting adult content viewable in the UK by July 2025. Allowable methods include facial age estimation. == Criticism == Adam Schwartz, a lawyer for the Electronic Frontier Foundation, criticized the use of facial age estimation software, noting its inaccuracy especially in cases of minorities and women, as was found in NIST's 2024 report. Twenty organisations jointly under European Digital Rights called the practice a "systematic and invasive processing of young people's data" that risks discriminatory profiling.

Amino (app)

Amino was a social media application originally developed by Narvii, Inc. It was originally created by Yin Wang and Ben Anderson in 2010, and then launched as an app in 2012. Amino was acquired by MediaLab AI Inc in January 2021, and the founders are no longer associated with the application. The platform ceased all operations in December 2025. == History == In 2010, Wang and Anderson came up with the idea for a convention-like community while attending an anime convention in Boston, Massachusetts. Later that year, they would release two apps revolving around K-pop and photography that allowed fans of those subjects to chat freely. That same year, Amino was officially released. === Shutdown === In early December 2025, the Amino platform abruptly stopped all operations. Users worldwide lost access to the mobile application and website, with server requests returning connection time-out errors. Parent company MediaLab AI has issued no official statement regarding the cause to date, or declared any possible cause behind it. === Final Message === According to Shawn, a member of Amino support, Amino has ceased operations as of December 19th. The message that was sent out from Shawn reads: "Hey there, Thanks for your message. Amino has ceased operations. As of December 19th, we no longer retain personal data relating to you. Accordingly, we are unable to provide a copy of your data. Kind regards, - Amino Support" This message was sent on January 4th, 2026. This was the final support message sent from the Amino Support mail. == Growth == Amino received 1.65 million dollars of seed funding in 2014, primarily from Union Ventures. Some additional seed investors include Google Ventures, SV Angel, Box Group, and other interested parties. By July 2014, Amino's apps were downloaded 500,000 times. Though only having 15 communities at that time, Amino eventually grew to have 41 communities in September 2015. Amino's apps had been downloaded 13 million times by July 2016. Fandoms had migrated from websites like Facebook and Reddit to Amino, partly because of the app's mobile-native experience. Before 2016, when a user wanted to join a new Amino, they had to download another app for the Amino they wanted to join, with each apps name beginning with "Amino for:". In 2016, Amino Apps launched a centralized portal that hosted every Amino community in one app, meaning users no longer had to download multiple apps. In July of the same year, ACM, an app that allowed users to create their own communities, was launched. This resulted in the number of communities on Amino skyrocketing to over 2.5 million as of June 2018. == Features == The main feature of Amino was communities dedicated to a certain topic that users could join. Users could also chat with other members of a community in three ways: text, voice, or screening room, which allowed users to watch videos together while voice chatting. Other features include polls, blog posts, image posts, wiki entries, stories, and quizzes. In some cases, posts that were very well-made and had been noticed by a community's administration would end up receiving a feature, making it appear on the front page along with other featured content. In 2018, a premium membership option called Amino+ was added. Amino+ comes with additional features such as exclusive stickers, the ability to make stickers, custom chat bubbles, high resolution images, and other perks. Membership can now only be purchased with money. Amino coins can be purchased or earned through enabling ads, watching ad videos, completing activities on the Offer Wall, and playing Lucky Draw when checking in, but are of little use due to the users not being able to buy Amino+ by amino coins anymore. Members can give and receive coins through props. In 2019, Amino introduced six original short-form animated series, labelled "Amino Originals," produced by independent artists from across the internet. ATJ's "Little Red," a re-imagining of Little Red Riding Hood, premiered on November 15, 2019. "Little Red" was joined by five other shows in late December. Sophie Feher's "The Reef," a comedy featuring an aspiring marine biologist meeting a merman, premiered on December 27 alongside "Princely," an LGBT fairy tale created by Matt Bruneau-Richardson of Tiny Siren Animation. "Spaced Out," an alien abduction comedy by Michael Jae, and YouTuber Alex Clark's "Wyndvania II" premiered on December 28. Mysie Pereira's fairy tale "Turned to Stone" and Marcin Pawlowski's "Stranded" premiered on December 29, 2019. == Administration == On each community, there are two types of staff members, these being ‘Leader’ and ‘Curator.’ Leaders are higher rank than curators. Curators are usually the ones who feature posts, or post important announcements for users to see. Curators are able to disable a post or public chat, delete comments or chat threads, manage featured content, manage posts in topic categories, and approve Wiki entries. Leaders have more power than curators. In addition to curator powers, leaders can submit a community to be listed, change the Amino's features, change navigation, alter the community appearance, change the Amino's privacy settings, manage the Amino's join requests, send invites, appoint or demote Curators, strike or ban members, manage flagged content, change users' custom titles, manage topics and wiki categories, and create broadcasts (notifications sent for posts). One leader will have the status of agent. An agent is the primary leader of a community; the person who created the community is automatically agent. An agent has the ability to delete their community as long as it is not too large or too active. An agent can appoint and remove both leaders and curators. Agent status can be transferred voluntarily to another leader, curator, or community member. If an agent is inactive, Team Amino may assist in transferring agent status. == Apps == === Amino Community Manager === Otherwise known as ACM, this application is what users use to create and manage their own community in Amino. This app allows moderators to customize a community's theme, icon, and categories. ACM also allows moderation to customize community descriptions, pick leaders, change language settings, create a tagline for the community, change the home page lay out, alter the side navigation menu, and more. Unlisted communities are able to change their community's title and Amino ID, but this is not an option once a community is listed. A leader can use ACM to submit a request for their community to be listed on the explore page, after which the community will be reviewed by Team Amino for approval. Communities can be deleted on ACM, but only by the agent of that community. == Guidelines == Amino has a set of guidelines that all communities must comply with. Amino does not allow harassment or hate, spam or self-promotion (including promotion of one's own Amino community), sexual/NSFW content, self harm, real graphic/gross content (fictional content is generally acceptable), unsafe/illegal content, or content that violates copyright. Communities are allowed to have additional rules so long as they do not violate Amino's rules. In addition to Amino's rules, users are required to be at least 13 years of age in the U.S. and 16 years of age in European Union countries. While sexual imagery is not allowed in any community and text based sexual content is not allowed in public areas, some private communities are allowed to discuss sexual themes. However, they are not exempt from Amino's rules on NSFW content. If guidelines are broken, a leader may disable content or impose a warning, strike, or ban, depending on the severity of the infringement. A warning is a message informing the user that they have violated a guideline and may face further punishment unless they change their behaviour. A strike will put the user in read-only mode for up to 24 hours; this mode prevents the user from posting, chatting, or interacting with posts in that community. A ban removes the user from the community. Team Amino can separately issue users with strikes or bans across the entire platform. == Controversies == In 2017, organizations in Argentina for the protection of minors reported inappropriate material on the app, ranging from pornography to material promoting suicide to underage users. In 2019, Abilene police in Texas released a statement that sexual predators were using Amino chat rooms to approach minors. In 2020, authorities from the Christian County in the state of Kentucky alerted parents about possible sexual predators on Amino. In 2025, the British Police identified Amino as one of several platforms used by a child exploitation network that had previously extorted minors in different countries in Europe and North America. Several families reported to the National Society for the Prevention of Cruelty to Children that pedophiles were using the app for the purpose of sexual role-playing with minors, c

Webby Awards

The Webby Awards (colloquially referred to as the Webbys) are awards for excellence on the Internet presented annually by the International Academy of Digital Arts and Sciences, a judging body composed of over three thousand industry experts and technology innovators. Categories include websites, advertising and media, online film and video, mobile sites and apps, and social. Two winners are selected in each category, one by members of The International Academy of Digital Arts and Sciences, and one by the public who cast their votes during Webby People's Voice voting. Each winner presents a five-word acceptance speech, a trademark of the annual awards show. In its early years, the award was hailed as the "Internet's highest honor" and was associated with the phrase "The Oscars of the Internet." == History == In its early years, the organization was one of several vying to be the premiere internet awards show. Both shows would compare themselves to the Oscars, as did media outlets such as The New York Times to Canada's Globe & Mail. The winners of the First Annual Webby Awards in 1995 were presented by John Brancato and Michael Ferris, writers for Columbia Pictures. It was held at the Hollywood Roosevelt Hotel. The televised Webby Awards were sponsored by the Academy of Web Design and Cool Site of the Day. The first Webby Awards were produced by Kay Dangaard at the Hollywood Roosevelt Hotel as a nod to the first site of the Academy of Motion Picture Arts and Sciences (Oscars). That first year, they were called "Webbie" Awards. The first "Site of the Year" winner was the pioneer webisodic serial The Spot. The modern Webby Awards were co-founded by Tiffany Shlain, a filmmaker, when she was hired by The Web Magazine to re-establish them, and were first held in San Francisco in 1997. They quickly became known for its requirement that winners give their acceptance speeches in five words. After this, the awards became more successful than the magazine and IDG closed the publication. Shlain and co-founder Maya Draisin Farrah continued to run The Webby Awards until 2004. The International Academy of Digital Arts and Sciences, which selects the winners of The Webby Awards, was established in 1998 by co-founders Tiffany Shlain, Spencer Ante and Maya Draisin. Members of the Academy include Kevin Spacey, Grimes, Questlove, Internet inventor Vint Cerf, Instagram's Head of Fashion Partnerships Eva Chen, comedian Jimmy Kimmel, Twitter founder Biz Stone, Vice Media co-founder and CEO Shane Smith, Tumblr's David Karp, Director of Harvard's Berkman Klein Center for Internet & Society Susan P. Crawford, Refinery29's Executive Creative Director Piera Gelardi, and CEO and co-founder of Gimlet Media Alex Blumberg. The Webby Awards is owned and operated by the Webby Media Group, a division of Recognition Media, which also owns and produces the Lovie Awards in Europe and Netted by the Webbys, a daily email publication launched in 2009. David-Michel Davies, CEO of Webby Media Group, current Executive Director of the Webby Awards and co-founder of Internet Week New York, was named Executive Director of the Webby Awards in 2005. In 2009, the 13th Annual Webby Awards received nearly 10,000 entries from all 50 US states and over 60 countries. That same year, more than 500,000 votes were cast in The Webby People's Voice Awards. In 2012, the 16th Annual Webby awards received 1.5 million votes from more than 200 countries for the People's Voice awards. In 2015, the 19th Annual Webby Awards received nearly 13,000 entries from all 50 U.S. states and over 60 countries worldwide. == Nomination process == The 2000 awards began the transition to nominee submissions. Previously, nominees had been selected by an internal committee. As early as 2017, organizations wanting to nominate themselves were charged $395 for a single entry. An "ad campaign entry" would cost $595. By 2024, those fees had risen to $495 and $675, respectively. Executive Academy Members with category-specific expertise evaluate the shortlisted entries based on the appropriate Website, Advertising & Media, Online Film & Video, Mobile Sites & Apps, and Social category criteria, and cast ballots to determine Webby Honorees, Nominees and Webby Winners. Deloitte provides vote tabulation consulting for the Webby Awards. In addition to the award given in each category by the International Academy of Digital Arts and Sciences, another winner is selected in each category as determined by the general public during People's Voice voting. Winners of both the Academy-selected and People's Voice-selected awards are invited to the Webbys. == Awards granted == The Webby Awards are presented in over a hundred categories among all four types of entries. A website can be entered in multiple categories and receive multiple awards. In each category, two awards are handed out: a Webby Award selected by The International Academy of Digital Arts and Sciences, and a People's Voice Award selected by the general public. == Ceremony == Between 2005 and 2019, the Webby Awards were presented in New York City. Many of the ceremony hosts are comedians and comedic actors. Comedian Rob Corddry hosted the ceremony from 2005 to 2007. Seth Meyers of Saturday Night Live hosted in 2008 and 2009, B.J. Novak of the sitcom The Office in 2010, and Lisa Kudrow in 2011. Comedian, actor, and writer Patton Oswalt hosted from 2012 to 2014. Comedian Hannibal Buress hosted in 2015. The Webbys are famous for limiting recipients to five-word speeches, which are often humorous, although some exceed the limit. In 2005 when accepting his Lifetime Achievement Award, former Vice President Al Gore's speech was "Please don't recount this vote." He was introduced by Vint Cerf who used the same format to state, "We all invented the Internet." In 2013, the creator of the Graphics Interchange Format (GIF), Steve Wilhite, accepted his Webby and delivered his now famous five-word speech, "It's pronounced 'Jif' not 'Gif'." == Criticism == The Webbys have been criticized for their pay-to-enter and pay-to-attend policy (winners and nominees also have to pay to attend the award ceremony), and thus for not taking most websites into consideration before distributing their awards. Gawker, its Valleywag column, and others, have called the awards a scam, with Valleywag saying, "...somewhere along the way, the organizers figured out that this goofy charade could be milked for profit." In response, Webby Awards executive director David-Michel Davies told the Wall Street Journal that entry fees "provide the best and most sustainable model for ensuring that our judging process remains consistent and rigorous and is not dependent on things like sponsorships that can fluctuate from year to year." == Anthem Awards == In 2021, the Webby organization started a new line of awards, the Anthem Awards, to honor the purpose and mission-driven work of people, companies and organizations worldwide. The finalists and winners are selected by the International Academy of Digital Arts and Sciences.

European Information Technology Observatory

The European Information Technology Observatory (EITO) gathers information on European and global markets for information technology, telecommunications and consumer electronics. The EITO is managed by Bitkom Research GmbH, a wholly owned subsidiary of BITKOM, the German Association for Information Technology, Telecommunications and New Media. EITO is sponsored by Deutsche Telekom, KPMG and Telecom Italia. The research activities of the EITO Task Force are supported by the European Commission and the OECD. The EITO exists thanks to an initiative of Enore Deotto from MIlan and the support of Luis-Alberto Petit Herrera (Madrid), Jörg Schomburg (Hanover) and Günther Möller (Frankfurt). Between 1993 and 2007, the market reports were published as printed annual reports ("EITO yearbook"). Since 2008 the market reports are available in electronic version and can be purchased on the EITO online portal. Currently, the ICT market reports are divided in following categories: International Reports International Reports include ICT market information of all EITO countries and all market segments or only specific segments. The newest ICT Market Report 2013/14, published in October 2013, includes market data of 36 countries: 28 European markets, BRIC countries, Japan, Turkey and the US as well as a deep analysis of ICT market developments in 9 European countries. The detailed market data and forecasts are available for the period 2010–2014. Country Reports This category includes EITO reports on a single country's ICT market. The Country ICT Market Reports are published biannually for France, Germany, Italy, Spain and the United Kingdom. Thematic Reports Thematic studies focusing on a specific topic. Customized Reports Market Reports made upon order.

Connected-component labeling

Connected-component labeling (CCL), connected-component analysis (CCA), blob extraction, region labeling, blob discovery, or region extraction is an algorithmic application of graph theory, where subsets of connected components are uniquely labeled based on a given heuristic. Connected-component labeling is not to be confused with segmentation. Connected-component labeling is used in computer vision to detect connected regions in binary digital images, although color images and data with higher dimensionality can also be processed. When integrated into an image recognition system or human-computer interaction interface, connected component labeling can operate on a variety of information. Blob extraction is generally performed on the resulting binary image from a thresholding step, but it can be applicable to gray-scale and color images as well. Blobs may be counted, filtered, and tracked. Blob extraction is related to but distinct from blob detection. == Overview == A graph, containing vertices and connecting edges, is constructed from relevant input data. The vertices contain information required by the comparison heuristic, while the edges indicate connected 'neighbors'. An algorithm traverses the graph, labeling the vertices based on the connectivity and relative values of their neighbors. Connectivity is determined by the medium; image graphs, for example, can be 4-connected neighborhood or 8-connected neighborhood. Following the labeling stage, the graph may be partitioned into subsets, after which the original information can be recovered and processed . == Definition == The usage of the term connected-component labeling (CCL) and its definition is quite consistent in the academic literature, whereas connected-component analysis (CCA) varies both in terminology and in its definition of the problem. Rosenfeld et al. define connected components labeling as the “[c]reation of a labeled image in which the positions associated with the same connected component of the binary input image have a unique label.” Shapiro et al. define CCL as an operator whose “input is a binary image and [...] output is a symbolic image in which the label assigned to each pixel is an integer uniquely identifying the connected component to which that pixel belongs.” There is no consensus on the definition of CCA in the academic literature. It is often used interchangeably with CCL. A more extensive definition is given by Shapiro et al.: “Connected component analysis consists of connected component labeling of the black pixels followed by property measurement of the component regions and decision making.” The definition for connected-component analysis presented here is more general, taking the thoughts expressed in into account. == Algorithms == The algorithms discussed can be generalised to arbitrary dimensions, albeit with increased time and space complexity. === One component at a time === This is a fast and very simple method to implement and understand. It is based on graph traversal methods in graph theory. In short, once the first pixel of a connected component is found, all the connected pixels of that connected component are labelled before going onto the next pixel in the image. This algorithm is part of Vincent and Soille's watershed segmentation algorithm, other implementations also exist. In order to do that a linked list is formed that will keep the indexes of the pixels that are connected to each other, steps (2) and (3) below. The method of defining the linked list specifies the use of a depth or a breadth first search. For this particular application, there is no difference which strategy to use. The simplest kind of a last in first out queue implemented as a singly linked list will result in a depth first search strategy. It is assumed that the input image is a binary image, with pixels being either background or foreground and that the connected components in the foreground pixels are desired. The algorithm steps can be written as: Start from the first pixel in the image. Set current label to 1. Go to (2). If this pixel is a foreground pixel and it is not already labelled, give it the current label and add it as the first element in a queue, then go to (3). If it is a background pixel or it was already labelled, then repeat (2) for the next pixel in the image. Pop out an element from the queue, and look at its neighbours (based on any type of connectivity). If a neighbour is a foreground pixel and is not already labelled, give it the current label and add it to the queue. Repeat (3) until there are no more elements in the queue. Go to (2) for the next pixel in the image and increment current label by 1. Note that the pixels are labelled before being put into the queue. The queue will only keep a pixel to check its neighbours and add them to the queue if necessary. This algorithm only needs to check the neighbours of each foreground pixel once and doesn't check the neighbours of background pixels. The pseudocode is: algorithm OneComponentAtATime(data) input : imageData[xDim][yDim] initialization : label = 0, labelArray[xDim][yDim] = 0, statusArray[xDim][yDim] = false, queue1, queue2; for i = 0 to xDim do for j = 0 to yDim do if imageData[i][j] has not been processed do if imageData[i][j] is a foreground pixel do check its four neighbors(north, south, east, west) : if neighbor is not processed do if neighbor is a foreground pixel do add it to queue1 else update its status to processed end if labelArray[i][j] = label (give label) statusArray[i][j] = true (update status) while queue1 is not empty do For each pixel in the queue do : check its four neighbors if neighbor is not processed do if neighbor is a foreground pixel do add it to queue2 else update its status to processed end if give it the current label update its status to processed remove the current element from queue1 copy queue2 into queue1 end While increase the label end if else update its status to processed end if end if end if end for end for === Two-pass === Relatively simple to implement and understand, the two-pass algorithm, (also known as the Hoshen–Kopelman algorithm) iterates through 2-dimensional binary data. The algorithm makes two passes over the image: the first pass to assign temporary labels and record equivalences, and the second pass to replace each temporary label by the smallest label of its equivalence class. The input data can be modified in situ (which carries the risk of data corruption), or labeling information can be maintained in an additional data structure. Connectivity checks are carried out by checking neighbor pixels' labels (neighbor elements whose labels are not assigned yet are ignored), or say, the north-east, the north, the north-west and the west of the current pixel (assuming 8-connectivity). 4-connectivity uses only north and west neighbors of the current pixel. The following conditions are checked to determine the value of the label to be assigned to the current pixel (4-connectivity is assumed) Conditions to check: Does the pixel to the left (west) have the same value as the current pixel? Yes – We are in the same region. Assign the same label to the current pixel No – Check next condition Do both pixels to the north and west of the current pixel have the same value as the current pixel but not the same label? Yes – We know that the north and west pixels belong to the same region and must be merged. Assign the current pixel the minimum of the north and west labels, and record their equivalence relationship No – Check next condition Does the pixel to the left (west) have a different value and the one to the north the same value as the current pixel? Yes – Assign the label of the north pixel to the current pixel No – Check next condition Do the pixel's north and west neighbors have different pixel values than current pixel? Yes – Create a new label id and assign it to the current pixel The algorithm continues this way, and creates new region labels whenever necessary. The key to a fast algorithm, however, is how this merging is done. This algorithm uses the union-find data structure which provides excellent performance for keeping track of equivalence relationships. Union-find essentially stores labels which correspond to the same blob in a disjoint-set data structure, making it easy to remember the equivalence of two labels by the use of an interface method E.g.: findSet(l). findSet(l) returns the minimum label value that is equivalent to the function argument 'l'. Once the initial labeling and equivalence recording is completed, the second pass merely replaces each pixel label with its equivalent disjoint-set representative element. A faster-scanning algorithm for connected-region extraction is presented below. On the first pass: Iterate through each element of the data by column, then by row (Raster Scanning) If the element is not the background Get the neighboring elements of the current element If there are no neighbors, uniquely

List of video games using NFC

This is a list of video games that use near field communication (NFC) technology. Currently, games have leveraged NFC in unlocking additional features through payment. This takes the form of a direct transaction over NFC or by purchasing a physical item, which signals to the platform that a certain set of features has been purchased (e.g. Skylanders). This list catalogues gaming NFC platforms by device. == Mobile == === Android === Gun Bros. Near Field Ninja NFC Cards Skylanders, with an NFC base. The Haunted House: Soul Fighters, with an NFC base. === iOS === ==== As item-triggered game enhancement ==== Skylanders, with an NFC base. ==== As payment ==== In-App Purchases Here, games that leverage Apple's In-App Purchase framework use information stored in the NFC Secure Element to process the purchase through Apple Pay. While an NFC radio is not used here, the NFC protocol is used nonetheless. == Console == === Nintendo Wii, Wii U, Switch, Switch 2, 3DS and 2DS === ==== As item-triggered game enhancement ==== Pokémon Rumble U NFC Figure Amiibo, built into Nintendo consoles since 2014. Works with Wii U, New Nintendo 3DS/3DS XL, New Nintendo 2DS XL, Nintendo Switch, Nintendo Switch 2 and older Nintendo 3DS/Nintendo 2DS systems via a peripheral device. Disney Infinity, with an NFC base. Works with Wii, Nintendo 3DS, Nintendo 2DS and Wii U. Lego Dimensions, with an NFC base. Works with Wii U. Skylanders, with an NFC base. Works with Wii, Nintendo 3DS, Nintendo 2DS and Wii U. The Nintendo Switch version of Skylanders: Imaginators uses the NFC built into the game controller, it is also has full backward compatibility with Nintendo Switch 2. Some functionalities are missing compared to the other versions. ==== As payment ==== The Wii U GamePad controller, Joy-Con R, Joy-Con 2 R, Nintendo Switch Pro Controller and Nintendo Switch 2 Pro Controller can read information from an NFC data source. === PlayStation === Disney Infinity, with an NFC base. Works with PlayStation 3, PlayStation Vita, PlayStation 4 and PlayStation 5. Lego Dimensions, with an NFC base. Works with PlayStation 3, PlayStation 4 and PlayStation 5. Skylanders, with an NFC base. Works with PlayStation 3, PlayStation 4 and PlayStation 5. === Xbox === While NFC bases are normally interoperable between all platforms, the Xbox 360, Xbox One and Xbox Series X require specific bases that are compatible only with the respective platform. Disney Infinity, with an NFC base. Lego Dimensions, with an NFC base. Skylanders, with an NFC base.