An automated dispensing cabinet (ADC), also called a unit-based cabinet (UBC), automated dispensing device (ADD), or automated dispensing machine (ADM)[1], is a computerized medicine cabinet for hospitals and healthcare settings. ADCs allow medications to be stored and dispensed near the point of care while controlling and tracking drug distribution. == Overview == Hospital pharmacies have provided medications for patients by filling patient-specific cassettes of unit-dose medications that were then delivered to the nursing unit and stored in medication cabinets or carts. ADCs, originally designed for hospital use, were introduced in hospitals in the 1980s and have facilitated the transition to alternative delivery models and more decentralized medication distribution systems.[2] Implementing automated dispensing cabinets as part of a decentralized or hybrid medication distribution system can improve patient safety and the accountability of the inventory, streamline certain billing processes. However, in the 2000s, the technology began to be deployed into other care settings where medication doses were stored onsite, and higher security methods were needed to control inventory, access, and dispensing of each patient dose. Settings that now deploy ADCs include long-term care facilities, hospice, critical access hospitals, surgery centers, group homes, residential care facilities, rehab and psych environments, animal health, dental clinics, and nursing education simulation. These diverse care settings share a common need to safely store, account for, and dispense individual doses of medications, especially narcotics and high-value medications, at the point of care.[3] ADCs track user access and dispensed medications, and their use can improve control over medication inventory. The real-time inventory reports generated by many cabinets can simplify the filling process and help the pharmacy track expired drugs. Furthermore, by restricting individual drugs – such as high-risk medications and controlled substances – to unique drawers within the cabinet, overall inventory management, patient safety, and medication security can be improved. Automated dispensing cabinets allow the pharmacy department to profile physician orders before they are dispensed.[4] ADCs can also enable providers to record medication charges upon dispensing, reducing the billing paperwork the pharmacy is responsible for. In addition, nurses can note returned medications using the cabinets' computers, enabling direct credits to patients' accounts. Since automated cabinets can be located on the nursing unit floor, nursing have speedier access to a patient's medications. Also, shorter waiting time ensures improved patient comfort and care.[5] == Role of automated dispensing in healthcare == Automated dispensing is a pharmacy practice in which a device dispenses medications and fills prescriptions. ADCs, which can handle many different medications, are available from a number of manufacturers such as BD, ARxIUM, and Omnicell. Though members of the pharmacy community have been utilizing automation technology since the 1980s, companies are constantly improving ADCs to meet changing needs and health standards in the industry. Several goals can be met by implementing an automated product in a healthcare facility. Patient safety can be ensured with the use of ADC technology such as barcoding. Anesthesia ADCs in operating rooms and perioperative areas may include label printing to prevent mix-ups such as errors between morphine and hydromorphone, two different opioid analgesics that frequently get confused. These systems also communicate with the pharmacy and its information management system to track medications removed and support inventory replenishment. == Key features == ADCs are like automated teller machines whose specific technologies such as barcode scanning and clinical decision support can improve medication safety. Some have metal locking drawers for added security and some have automated single-dose dispensing to prevent the need for a blind count each time a controlled substance is accessed. Over the years, ADCs have been adapted to facilitate compliance with emerging regulatory requirements such as pharmacy review of medication orders and safe practice recommendations. ADCs incorporate advanced software and electronic interfaces to synthesize high-risk steps in the medication use process. These unit-based medication repositories provide computer-controlled storage, dispensation, tracking, and documentation of medication distribution in the resident care unit. Since automated dispensing cabinets are not located in the pharmacy, they are considered "decentralized" medication distribution systems. Instead, they can be found at the point of care on the resident care unit. Tracking of the stocking and distribution process can occur by interfacing the unit with a central pharmacy computer. These cabinets can also be interfaced with other external databases such as resident profiles, the facility's admission/discharge/transfer system, and billing systems. Most ADC providers offer scalable systems since several important factors vary widely by facility such as budget, physical room size, patient population/demographics, type of healthcare facility, etc.
Label noise
Label noise refers to errors or inaccuracies in the class labels of data instances. This is a widespread issue in machine learning datasets, arising from human annotator mistakes, unclear labeling instructions, automated labeling methods, or adversarial attacks in supervised learning. Label noise can be roughly divided into random noise, where labels are flipped independently of input features, and systematic noise, where mislabeling is dependent on certain patterns or biases in the data. Label noise can be damaging to model performance, especially for complex models that may overfit to noisy labels rather than generalizable patterns. Many approaches have been proposed to deal with the effects of label noise, including robust loss functions, noise-tolerant algorithms, data cleaning methods, and semi-supervised learning approaches. To reduce the impact of wrong labels during training, techniques like label smoothing, sample reweighting and using trusted validation sets are used. The role of noise-robust training paradigms and curriculum learning strategies to improve resilience against mislabeled data is also explored in recent research.
NRD Cyber Security
NRD Cyber Security is a Lithuanian company that provides cybersecurity solutions, consulting, and other services. The organization specializes in CSIRT and SOC creation, modernization and training. It has helped to establish national and sectorial CSIRTs around the world, including countries, such as Bangladesh, Egypt, Bhutan, Kosovo, Malawi and others. NRD Cyber Security was found in 2013 to provide quality cybersecurity services to nations and organizations. In 2018 it was included in The Deloitte Technology Fast 50 in Europe list. In 2024 it was awarded the #98 place in MSSP Alert Top 250 world's managed security service providers. The company is a member of various cybersecurity organizations, such as Forum of Incident Response and Security Teams (FIRST), The Global Forum on Cyber Expertise (GFCE), Unicrons Lt. It is a strategic partner of The Global Cyber Security Capacity Centre (GCSCC) at University of Oxford.
Reflection lines
Engineers use reflection lines to judge a surface's quality. Reflection lines reveal surface flaws, particularly discontinuities in normals indicating that the surface is not C 2 {\displaystyle C^{2}} . Reflection lines may be created and examined on physical surfaces or virtual surfaces with the help of computer graphics. For example, the shiny surface of an automobile body is illuminated with reflection lines by surrounding the car with parallel light sources. Virtually, a surface can be rendered with reflection lines by modulating the surfaces point-wise color according to a simple calculation involving the surface normal, viewing direction and a square wave environment map. == Mathematical definition == Consider a point p {\displaystyle p} on a surface M {\displaystyle M} with (normalized) normal n {\displaystyle n} . If an observer views this point from infinity at view direction v {\displaystyle v} then the reflected view direction r {\displaystyle r} is: r = v − 2 ( n ⋅ v ) n . {\displaystyle r=v-2(n\cdot v)n.} (The vector v {\displaystyle v} is decomposed into its normal part v n = ( n ⋅ v ) v {\displaystyle v_{n}=(n\cdot v)v} and tangential part v t = v − v n {\displaystyle v_{t}=v-v_{n}} . Upon reflection, the tangential part is kept and the normal part is negated.) For reflection lines we consider the surface M {\displaystyle M} surrounded by parallel lines with direction a {\displaystyle a} , representing infinite, non-dispersive light sources. For each point p {\displaystyle p} on M {\displaystyle M} we determine which line is seen from direction v {\displaystyle v} . The position on each line is of no interest. Define the vector r p {\displaystyle r_{p}} to be the reflection direction r {\displaystyle r} projected onto a plane P {\displaystyle P} that is orthogonal to a {\displaystyle a} : r p = r − ( r ⋅ a ) a {\displaystyle r_{p}=r-(r\cdot a)a} and similarly let v p {\displaystyle v_{p}} be the viewing direction projected onto P {\displaystyle P} : v p = v − ( v ⋅ a ) a {\displaystyle v_{p}=v-(v\cdot a)a} Finally, define v o {\displaystyle v_{o}} to be the direction lying in P {\displaystyle P} perpendicular to a {\displaystyle a} and v p {\displaystyle v_{p}} : v o = a × v p {\displaystyle v_{o}=a\times v_{p}} Using these vectors, the reflection line function θ ( p ) : M → ( − π , π ] {\displaystyle \theta (p):M\rightarrow (-\pi ,\pi ]} is a scalar function mapping points p {\displaystyle p} on the surface to angles between v p {\displaystyle v_{p}} and r p {\displaystyle r_{p}} : θ = arctan ( r p ⋅ v o , r p ⋅ v p ) {\displaystyle \theta =\arctan {(r_{p}\cdot v_{o},r_{p}\cdot v_{p})}} where a r c t a n ( y , x ) {\displaystyle arctan(y,x)} is the atan2 function producing a number in the range ( − π , π ] {\displaystyle (-\pi ,\pi ]} . ( v p {\displaystyle v_{p}} and v o {\displaystyle v_{o}} can be viewed as a local coordinate system in P {\displaystyle P} with x {\displaystyle x} -axis in direction v p {\displaystyle v_{p}} and y {\displaystyle y} -axis in direction v o {\displaystyle v_{o}} .) Finally, to render the reflection lines positive values θ > 0 {\displaystyle \theta >0} are mapped to a light color and non-positive values to a dark color. == Highlight lines == Highlight lines are a view-independent alternative to reflection lines. Here the projected normal is directly compared against some arbitrary vector x {\displaystyle x} perpendicular to the light source: θ = arctan ( n a ⋅ a ⊥ , n a ⋅ x ) {\displaystyle \theta =\arctan {(n_{a}\cdot a^{\perp },n_{a}\cdot x)}} where n a {\displaystyle n_{a}} is the surface normal projected on the light source plane P {\displaystyle P} : n a ^ / | n a ^ | , n a ^ = n − ( n ⋅ a ) a {\displaystyle {\hat {n_{a}}}/|{\hat {n_{a}}}|,{\hat {n_{a}}}=n-(n\cdot a)a} The relationship between reflection lines and highlight lines is likened to that between specular and diffuse shading.
Digital curation
Digital curation is the selection, preservation, maintenance, collection, and archiving of digital assets. It is a process that establishes, maintains, and adds value to repositories of digital data for present and future use. The implementation of digital curation is often carried out by archivists, librarians, scientists, historians, and scholars to ensure users have access to reliable, high-quality resources. Enterprises are also starting to adopt digital curation as a means to improve the quality of information and data within their operational and strategic processes. A successful digital curation initiative will help to mitigate digital obsolescence, keeping the information accessible to users indefinitely. Digital curation includes various aspects, including digital asset management, data curation, digital preservation, and electronic records management. == Word History == Much like the word archive has layered meanings and uses, the word curation is both a noun and a verb, used originally in the field of museology to represent a wide range of activities, most often associated with collection care, long-term preservation, and exhibition design. Curation can be a reference to physical repositories that store cultural heritage or natural resource collections (e.g., a curatorial repository) or a representation of varied policies and processes involved with the long-term care and management of heritage collections, digital archives, and research data (e.g, curatorial/collections management plans, curation life-cycle, and data curation). Yet curation is also associated with short-term objectives and processes of selection and interpretation for the purposes of presentation, such as for gallery exhibitions and websites, which contribute to knowledge creation. It has also been applied to interaction with social media including compiling digital images, web links, and movie files. The term curation entered the legal framework through federal historic preservation laws, starting with the National Historic Preservation Act of 1966, and was further defined and coded into federal regulations through 36 CFR Part 79: Curation of Federally-owned and Administered Archaeological Collections. Curation has since permeated into an array of disciplines but remains closely tied to heritage and information management. == Core Principles and Activities == The term "digital curation" was first used in the e-science and biological science fields as a means of differentiating the additional suite of activities ordinarily employed by library and museum curators to add value to their collections and enable its reuse from the smaller subtask of simply preserving the data, a significantly more concise archival task. Additionally, the historical understanding of the term "curator" demands more than simple care of the collection. A curator is expected to command academic mastery of the subject matter as a requisite part of appraisal and selection of assets and any subsequent adding of value to the collection through application of metadata. === Principles === There are five commonly accepted principles that govern the occupation of digital curation: Manage the complete birth-to-retirement life cycle of the digital asset. Evaluate and cull assets for inclusion in the collection. Apply preservation methods to strengthen the asset’s integrity and reusability for future users. Act proactively throughout the asset life cycle to add value to both the digital asset and the collection. Facilitate the appropriate degree of access to users. === Methodology === The Digital Curation Center offers the following step-by-step life cycle procedures for putting the above principles into practice: Sequential Actions: Conceptualize: Consider what digital material you will be creating and develop storage options. Take into account websites, publications, email, among other types of digital output. Create: Produce digital material and attach all relevant metadata, typically the more metadata the more accessible the information. Appraise and select: Consult the mission statement of the institution or private collection and determine what digital data is relevant. There may also be legal guidelines in place that will guide the decision process for a particular collection. Ingest: Send digital material to the predetermined storage solution. This may be an archive, repository or other facility. Preservation action: Employ measures to maintain the integrity of the digital material. Store: Secure data within the predetermined storage facility. Access, use, and reuse: Determine the level of accessibility for the range of digital material created. Some material may be accessible only by password and other material may be freely accessible to the public. Routinely check that material is still accessible for the intended audience and that the material has not been compromised through multiple uses. Transform: If desirable or necessary the material may be transferred into a different digital format. Occasional Actions: Dispose: Discard any digital material that is not deemed necessary to the institution. Reappraise: Reevaluate material to ensure that is it still relevant and is true to its original form. Migrate: Migrate data to another format in order to protect data for using better in the future. == Related terms == The term "digital curation" is sometimes used interchangeably with terms such as "digital preservation" and "digital archiving." While digital preservation does focus a significant degree of energy on optimizing reusability, preservation remains a subtask to the concept of digital archiving, which is in turn a subtask of digital curation. For example, archiving is a part of curation, but so are subsequent tasks such as themed collection-building, which is not considered an archival task. Similarly, preservation is a part of archiving, as are the tasks of selection and appraisal that are not necessarily part of preservation. Data curation is another term that is often used interchangeably with digital curation, however common usage of the two terms differs. While "data" is a more all-encompassing term that can be used generally to indicate anything recorded in binary form, the term "data curation" is most common in scientific parlance and usually refers to accumulating and managing information relative to the process of research. Data-driven research of education request the role of information professional gradually develop tradition of digital service to data curation particularly at the management of digital research data. So, while documents and other discrete digital assets are technically a subset of the broader concept of data, in the context of scientific vernacular digital curation represents a broader purview of responsibilities than data curation due to its interest in preserving and adding value to digital assets of any kind. == Challenges == === Rate of creation of new data and data sets === The ever lowering cost and increasing prevalence of entirely new categories of technology has led to a quickly growing flow of new data sets. These come from well established sources such as business and government, but the trend is also driven by new styles of sensors becoming embedded in more areas of modern life. This is particularly true of consumers, whose production of digital assets is no longer relegated strictly to work. Consumers now create wider ranges of digital assets, including videos, photos, location data, purchases, and fitness tracking data, just to name a few, and share them in wider ranges of social platforms. Additionally, the advance of technology has introduced new ways of working with data. Some examples of this are international partnerships that leverage astronomical data to create "virtual observatories," and similar partnerships have also leveraged data resulting from research at the Large Hadron Collider at CERN and the database of protein structures at the Protein Data Bank. === Storage format evolution and obsolescence === By comparison, archiving of analog assets is notably passive in nature, often limited to simply ensuring a suitable storage environment. Digital preservation requires a more proactive approach. Today’s artifacts of cultural significance are notably transient in nature and prone to obsolescence when social trends or dependent technologies change. This rapid progression of technology occasionally makes it necessary to migrate digital asset holdings from one file format to another in order to mitigate the dangers of hardware and software obsolescence which would render the asset unusable. === Underestimation of human labor costs === Modern tools for program planning often underestimate the amount of human labor costs required for adequate digital curation of large collections. As a result cost-benefit assessments often paint an inaccurate picture of both the amount of work involved and the true cost to the institution for bot
Toy problem
In scientific disciplines, a toy problem or a puzzlelike problem is a problem that is not of immediate scientific interest, yet is used as an expository device to illustrate a trait that may be shared by other, more complicated, instances of the problem, or as a way to explain a particular, more general, problem solving technique. A toy problem is useful to test and demonstrate methodologies. Researchers can use toy problems to compare the performance of different algorithms. They are also good for game designing. For instance, while engineering a large system, the large problem is often broken down into many smaller toy problems which have been well understood in detail. Often these problems distill a few important aspects of complicated problems so that they can be studied in isolation. Toy problems are thus often very useful in providing intuition about specific phenomena in more complicated problems. As an example, in the field of artificial intelligence, classical puzzles, games and problems are often used as toy problems. These include sliding-block puzzles, N-Queens problem, missionaries and cannibals problem, tic-tac-toe, chess, Tower of Hanoi and others.
Central Equipment Identity Register
A Central Equipment Identity Register (CEIR) is a database of mobile equipment identifiers (IMEI – for networks of GSM standard, MEID – for networks of CDMA standard). Such an identifier is assigned to each SIM slot of the mobile device. Different kinds of IMEIs could be, White, for devices that are allowed to register in the cellular network; Black, for devices that are prohibited to register in the cellular network; and Grey, for devices in intermediate status (when it is not yet defined in which of the lists - black or white - the device should be placed). Depending on the rules of mobile equipment registration in a country the CEIR database may contain other lists or fields beside IMEI. For example, the subscriber number (MSISDN), which is bound to the IMEI, the ID of the individual (passport data, National ID, etc.) who registered IMEI in the database, details of the importer who brought the device into the country, etc. == History == Originally abbreviation CEIR stood for IMEI Database, created and provided by GSM Association. It was proposed to blacklist the IMEIs of stolen or lost phones. It was assumed that any MNO would be able to receive this list to block the registration of such devices on their network. Thus, it turns out that a stolen phone, once blacklisted by the GSMA CEIR, cannot be used on a large number of cellular networks, which means that the theft of mobile devices will become meaningless. However, it soon became clear that the MNOs on their initiative were not going to do this because if many phones stopped working in their networks, but works in another, it puts them at a disadvantage and can lead to an outflow of subscribers. It became clear that the blocking of stolen devices should be introduced simultaneously in all mobile networks of the country by legislative measures at the initiative of the communications regulator. In this case, as a rule, a national IMEI database is created, which contains general lists of blocked IMEIs. Since the registration in the cellular operator's network is directly blocked by a network node called EIR (Equipment Identity Register), the system that contains the national IMEI base became known as Central EIR (CEIR). To avoid confusion the database of GSM Association was renamed to IMEI Database - IMEI DB (it was in 2003-2008, see “Document History” at IMEI Database File Format Specification). Also sometimes a common IMEI database for several EIRs is called SEIR (Shared EIR). In each country, the CEIR can interact with IMEI DB differently. National CEIR may not communicate with IMEI DB at all. Firstly, it is separately decided whether CEIR will send information about its blacklist to IMEI DB (which IMEIs are placed in it or removed from there). Secondly, upon receipt of the blacklist from IMEI DB, the regulator decides from which countries it will receive it (IMEI DB stores the information exactly who blacklisted the IMEI). For example, you can get a list from neighboring countries, from countries in your region, from around the world. In addition to the blacklist, the GSMA is developing a list of IMEIs allocated to manufacturers for use in their devices. The manufacturer for each new device model gets at least one TAC (Type Allocation Code) allocated by GSMA, consisting of 8 digits, to which he can add a 6-digit serial number to obtain the IMEI. Thus, with one TAC, a manufacturer can release up to 1 million devices with a unique IMEI. Usually, CEIR receives a list of allocated TACs from the GSMA, since if the first 8 digits of the IMEI of a device are not in this list, this is a sign that it is counterfeit. If the central database of identifiers does not work with GSM networks, but with CDMA, then for the same purposes it is necessary to interact with another worldwide database that contains MEIDs – MEID Database. A system that directly blocks the registration of a mobile device on a cellular network – EIR. Each MNO must have at least one EIR, to which IMEI check requests (CheckIMEI) are sent when registering a device on the network. A typical EIR and CERI interaction scheme: The CEIR accumulates black, white, and grey lists using various data sources and verification methods. These lists are periodically transmitted to all EIRs. EIR uses them when processing every CheckIMEI request to determine whether to allow the device on the network or not. EIR can transmit some data to the CEIR database too. Usually, changes in a grey list – new IMEIs on the network that are not in any list – are transmitted from EIR to CEIR. In addition to synchronizing lists across multiple networks, the main function of CEIR is to implement the scenarios of changes at these lists. This usually requires interaction with various IT systems (databases) of other organizations and/or with subscribers. Еxamples of such scenarios: Whitelisting the IMEI of devices imported by the legal entity Whitelisting the IMEI of devices manufactured domestically Whitelisting the IMEI of devices imported by individual Blacklisting the IMEI of stolen/lost devices Binding IMEI to the subscriber's number and, vice versa, unbinding IMEI from the subscriber == System implementation results == The goals and results of CEIR implementation in a country are usually: Reducing mobile phone theft Reducing the import of devices stolen in other countries Reducing the presence of counterfeit devices on the market (null IMEI, incorrect IMEI, changed IMEI) Reducing illegal imports of mobile devices (increase in the collection of customs duties) Additionally, CEIR most often contributes to the solution of such problems: Combating various mobile fraud schemes Obtaining more accurate statistics on the state of the mobile communications market for the regulator Fight against terrorism (the ability to block the device at once in all mobile networks of the country). Known results achieved in some countries: Great Britain – reducing mobile phone theft. Turkey – reducing mobile phone theft, decreasing the current account deficit of Turkey and maximizing tax revenues. Uzbekistan – preventing black import of mobile devices by 98%, increase in revenues from the import of mobile devices by 700%. Kenya – disposing the market of counterfeit mobile equipment. Azerbaijan – disposing the market of counterfeit mobile equipment. Ukraine – increasing of legally imported mobile devices by 95%, increase in revenues from the import of mobile devices. == CEIR and EIR manufacturers == Some countries have used local developers to implement CEIR for their country (Great Britain, Turkey, India, and Azerbaijan). EIR is a system that is standardized in a 2G-5G networks. Such system may be established at mobile network even it doesn’t use black list and there are no CEIR in a country. Some developers of MNO’s signal core include EIR in a complex solution. However, its standard capabilities are usually lacking for specific requirements when implementing CEIR.