Media engagement framework

Media engagement framework

The media engagement framework is a planning framework used by marketing professionals to understand the behavior of social media marketing-based audiences. The construct was introduced in the book, ROI of Social Media. Powell’s background in marketing ROI and Groves' experience and understanding of the applications of social media in business led to a collaboration. Dimos joined as a brand strategist for Litmus Group, a global management consulting firm. The media engagement framework consists of the definitions of personas (Individuals, Consumers and Influencers), referenced by the competitive set or constraint that applies to that persona and the measurement framework that might be applied to those personas. It is referenced at the center of the marketing process diagram, surrounded by the marketing functions of strategy, tactics, metrics and ROI. The marketing process diagram describes how the media engagement framework can apply to any strategic marketing activity but was developed to establish a completely integrated framework describing how both traditional and social media marketing activities can be planned, executed, measured and improved. == Application == The media engagement framework provides a strategic planning construct in which measurements and metrics play a crucial role. Applying the media engagement framework aids in the development and management of an effective online marketing presence leveraging social media to engage a market or audience. By first personifying the audience, the marketer is able to identify the limiting aspect of the engagements possible with that audience segment and then, understand the type of engagement metrics to apply. Each persona makes decisions differently about how he/she acts in the social media universe. A framework metric can be applied for each of these personas: Endorsement funnel for influencers Community engagement funnel for individuals Purchase funnel for consumers Individuals, influencers and consumers make decisions based on alternatives available to them and constraints put on them. To engage with an individual brands must realize they are competing against the time an individual spends on line. If they find something else more engaging, they will engage with that activity. Brands compete against other brands for the purchases of consumers acting in the category. Lastly, influencers have only so many endorsements they can make and therefore brands compete with other endorsers for the endorsement of an influencer. Creating engaging content by keeping target audience in mind like create content that audience find it funny, interesting, and relatable will encourage audience to share it on social networks. Which will be beneficial for you brand, getting more people to know about your business and brand. Contact Digilord to create engaging content for your brand. Use of listening tools (Google Alerts, Twitter Search, SocialMention.com, Veooz.com, Alterian SM2, Radian6, Sysomos, Buzzient etc.) can be employed within the model to help identify the members of the audience segment and to support the formation of other social engagement planning and management tools.

Autonomous aircraft

An autonomous aircraft is an aircraft which flies under the control of on-board autonomous robotic systems and needs no intervention from a human pilot or remote control. Most contemporary autonomous aircraft are unmanned aerial vehicles (drones) with pre-programmed algorithms to perform designated tasks, but advancements in artificial intelligence technologies (e.g. machine learning) mean that autonomous control systems are reaching a point where several air taxis and associated regulatory regimes are being developed. == History == === Unmanned aerial vehicles === The earliest recorded use of an unmanned aerial vehicle for warfighting occurred in July 1849, serving as a balloon carrier (the precursor to the aircraft carrier) Significant development of radio-controlled drones started in the early 1900s, and originally focused on providing practice targets for training military personnel. The earliest attempt at a powered UAV was A. M. Low's "Aerial Target" in 1916. Autonomous features such as the autopilot and automated navigation were developed progressively through the twentieth century, although techniques such as terrain contour matching (TERCOM) were applied mainly to cruise missiles. Before the introduction of the Bayraktar Kızılelma some modern drones have a high degree of autonomy, although they were not fully capable and the regulatory environment prohibits their widespread use in civil aviation. However some limited trials had been undertaken. On December 17, 2025, two Bayraktar Kızılelma performed the world's first autonomous close-formation flight by two unmanned fighter jets, using artificial intelligence. This was the first time in the history of aviation when two unmanned aerial vehicles flew in close formation on their own. === Passengers === As flight, navigation and communications systems have become more sophisticated, safely carrying passengers has emerged as a practical possibility. Autopilot systems are relieving the human pilot of progressively more duties, but the pilot currently remains necessary. A number of air taxis are under development and larger autonomous transports are also being planned. The personal air vehicle is another class where from one to four passengers are not expected to be able to pilot the aircraft and autonomy is seen as necessary for widespread adoption. == Control system architecture == The computing capability of aircraft flight and navigation systems followed the advances of computing technology, beginning with analog controls and evolving into microcontrollers, then system-on-a-chip (SOC) and single-board computers (SBC). === Sensors === Position and movement sensors give information about the aircraft state. Exteroceptive sensors deal with external information like distance measurements, while proprioceptive ones correlate internal and external states. Degrees of freedom (DOF) refers to both the amount and quality of sensors on board: 6 DOF implies 3-axis gyroscopes and accelerometers (a typical inertial measurement unit – IMU), 9 DOF refers to an IMU plus a compass, 10 DOF adds a barometer and 11 DOF usually adds a GPS receiver. === Actuators === UAV actuators include digital electronic speed controllers (which control the RPM of the motors) linked to motors/engines and propellers, servomotors (for planes and helicopters mostly), weapons, payload actuators, LEDs and speakers. === Software === UAV software called the flight stack or autopilot. The purpose of the flight stack is to obtain data from sensors, control motors to ensure UAV stability, and facilitate ground control and mission planning communication. UAVs are real-time systems that require rapid response to changing sensor data. As a result, UAVs rely on single-board computers for their computational needs. Examples of such single-board computers include Raspberry Pis, Beagleboards, etc. shielded with NavIO, PXFMini, etc. or designed from scratch such as NuttX, preemptive-RT Linux, Xenomai, Orocos-Robot Operating System or DDS-ROS 2.0. Civil-use open-source stacks include: Due to the open-source nature of UAV software, they can be customized to fit specific applications. For example, researchers from the Technical University of Košice have replaced the default control algorithm of the PX4 autopilot. This flexibility and collaborative effort has led to a large number of different open-source stacks, some of which are forked from others, such as CleanFlight, which is forked from BaseFlight and from which three other stacks are forked from. === Loop principles === UAVs employ open-loop, closed-loop or hybrid control architectures. Open loop – This type provides a positive control signal (faster, slower, left, right, up, down) without incorporating feedback from sensor data. Closed loop – This type incorporates sensor feedback to adjust behavior (reduce speed to reflect tailwind, move to altitude 300 feet). The PID controller is common. Sometimes, feedforward is employed, transferring the need to close the loop further. == Communications == Most UAVs use a radio for remote control and exchange of video and other data. Early UAVs had only narrowband uplink. Downlinks came later. These bi-directional narrowband radio links carried command and control (C&C) and telemetry data about the status of aircraft systems to the remote operator. For very long range flights, military UAVs also use satellite receivers as part of satellite navigation systems. In cases when video transmission was required, the UAVs will implement a separate analog video radio link. In most modern autonomous applications, video transmission is required. A broadband link is used to carry all types of data on a single radio link. These broadband links can leverage quality of service techniques to optimize the C&C traffic for low latency. Usually, these broadband links carry TCP/IP traffic that can be routed over the Internet. Communications can be established with: Ground control – a military ground control station (GCS). The MAVLink protocol is increasingly becoming popular to carry command and control data between the ground control and the vehicle. Remote network system, such as satellite duplex data links for some military powers. Downstream digital video over mobile networks has also entered consumer markets, while direct UAV control uplink over the cellular mesh and LTE have been demonstrated and are in trials. Another aircraft, serving as a relay or mobile control station – military manned-unmanned teaming (MUM-T). As mobile networks have increased in performance and reliability over the years, drones have begun to use mobile networks for communication. Mobile networks can be used for drone tracking, remote piloting, over the air updates, and cloud computing. Modern networking standards have explicitly considered autonomous aircraft and therefore include optimizations. The 5G standard has mandated reduced user plane latency to 1ms while using ultra-reliable and low-latency communications. == Autonomy == Basic autonomy comes from proprioceptive sensors. Advanced autonomy calls for situational awareness, knowledge about the environment surrounding the aircraft from exteroceptive sensors: sensor fusion integrates information from multiple sensors. Civil aviation regulators and standards bodies have published high-level roadmaps and discussion papers focused on assurance, safety and governance of AI-enabled systems in aviation, particularly as autonomy increases in operations and decision support. === Basic principles === One way to achieve autonomous control employs multiple control-loop layers, as in hierarchical control systems. As of 2016 the low-layer loops (i.e. for flight control) tick as fast as 32,000 times per second, while higher-level loops may cycle once per second. The principle is to decompose the aircraft's behavior into manageable "chunks", or states, with known transitions. Hierarchical control system types range from simple scripts to finite state machines, behavior trees and hierarchical task planners. The most common control mechanism used in these layers is the PID controller which can be used to achieve hover for a quadcopter by using data from the IMU to calculate precise inputs for the electronic speed controllers and motors. Examples of mid-layer algorithms: Path planning: determining an optimal path for vehicle to follow while meeting mission objectives and constraints, such as obstacles or fuel requirements Trajectory generation (motion planning): determining control maneuvers to take in order to follow a given path or to go from one location to another Trajectory regulation: constraining a vehicle within some tolerance to a trajectory Evolved UAV hierarchical task planners use methods like state tree searches or genetic algorithms. === Autonomy features === UAV manufacturers often build in specific autonomous operations, such as: Self-level: attitude stabilization on the pitch and roll axes. Altitude hold: The aircraft maint

AI-assisted virtualization software

AI-assisted virtualization software is a type of technology that combines the principles of virtualization with advanced artificial intelligence (AI) algorithms. This software is designed to improve efficiency and management of virtual environments and resources. This technology has been used in cloud computing and for various industries. == History == Virtualization originated in mainframe computers in the 1960s in order to divide system resources between different applications. The term has since broadened. The use of AI in virtualization significantly increased in the early 2020s. == Uses == AI-assisted virtualization software uses AI-related technology such as machine learning, deep learning, and neural networks to attempt to make more accurate predictions and decisions regarding the management of virtual environments. Features include intelligent automation, predictive analytics, and dynamic resource allocation. Intelligent Automation: Automating tasks such as resource provisioning and routine maintenance. The AI learns from ongoing operations and can predict and perform necessary tasks autonomously. Predictive Analytics: Utilizing AI to analyze data patterns and trends, predicting future issues or resource requirements. It aids in proactive management and mitigation of potential problems. Dynamic Resource Allocation: Through the analysis of real-time and historical data, the AI system dynamically assigns resources based on demand and need, optimizing overall system performance and reducing wastage. AI-assisted virtualization software has been used in cloud computing to optimize the use of resources and reduce costs. In healthcare, these technologies have been used to create virtual patient profiles. They are also used in data centers to improve performance and energy efficiency. It has also been used in network function virtualization (NFV) to improve virtual network infrastructure. Implementing this type of software requires a high degree of technological sophistication and can incur significant costs. There are also concerns about the risks associated with AI, such as algorithmic bias and security vulnerabilities. Additionally, there are issues related to governance, the ethics of artificial intelligence, and regulations of AI technologies.

Alec Radford

Alec Radford is an American artificial intelligence researcher. == Biography == Radford grew up in Texas. He graduated from Cistercian Preparatory School in 2011, where he became an Eagle Scout, and dropped out of Olin College in August 2014, where he and fellow students Slater Victoroff, Diana Yuan, and Madison May had formed the startup Indico in their dorm room. In 2015, the quartet were joined by Luke Metz and the firm and the Facebook AI research lab in New York used generative adversarial networks to create realistic low pixel images. A demonstration of Indico's technology was used without proper attribution in an April 2016 demonstration by Nvidia chief executive Jensen Huang. Radford joined OpenAI around 2016, where he worked on natural-language processing. The following year, Radford trained a neural network on Amazon reviews. The model was fairly basic, with layers which allowed for human understanding. Upon exploring it, he saw that it had a special neuron linked to the sentiment of the reviews, which it had created on its own. This was a drastic improvement from previous neural networks that had analysed sentiment, because they had to be told to do so and specially trained on data that was explicitly labeled according to sentiment. This development made OpenAI chief scientist Ilya Sutskever consider that a future model, using more diverse language data, could map far more structures of meaning, eventually becoming a "learned core module" for superintelligence. In 2018, Radford was the lead author on OpenAI's seminal research paper on generative pre-trained transformers, which form the foundation of ChatGPT. At OpenAI, he worked on early GPT models, Whisper, a speech recognition model, and the image generator DALL-E. He left OpenAI in December 2024 to pursue independent research. Around March 2025, Radford joined Thinking Machines Lab as an advisor. He joined along with Bob McGrew who was previously the chief research officer of OpenAI. In April 2026, Radford, Nick Levine, and David Duvenaud released Talkie, an AI model trained on books, newspapers, scientific journals, patents, and case law published before December 31, 1930. When asked about the state of the world in 2026, it stated that one billion people would live in Europe, that London and New York would be connected by steamships that transit between the two in ten days, and "winter will be passed in Paris, and the summer in London."

Common Crawl

The Common Crawl Foundation (Common Crawl) is a nonprofit 501(c)(3) organization that crawls the web and freely provides its archives and datasets to the public. Common Crawl was founded by Gil Elbaz. The data had mostly been primarily used by researchers and some startups until the 2020s, when AI companies started training large language models using the data. In November 2025, an investigation by The Atlantic revealed that Common Crawl misled publishers when it claimed it respected paywalls in its scraping and it was not honoring requests from publishers to have their content removed from its databases. == History == Common Crawl was founded in 2007 in San Francisco. It began publishing its crawls in 2011. By 2013, sites like TinEye were building their products off of Common Crawl. The crawl reduces the reliance of companies and researchers on Google, which has the biggest dataset. Common Crawl was designed to have more and fresher data that was more efficient to analyze and utilize than the Wayback Machine created by the Internet Archive. By 2015, 1.8 billion webpages were on the Common Crawl, which started by crawling a list of URLs donated by the search engine Blekko. They use Amazon Web Services, which provides some of its services for free, allowing computing costs to average $2-4000/month. The Common Crawl website listed 30 studies based on Common Crawl data. Before 2023, Common Crawl was not very well known outside of academic researchers who utilize the data. Common Crawl received its first requests to redact information in 2023 and increasingly started seeing its crawler, CCBot, blocked. In 2023, it began receiving significant financial support from AI companies, including Anthropic and OpenAI, each of which donated $250,000. It was also used to train Google DeepMind's large language model Gemini. By April 2023, Common Crawl was capturing 3.1 billion webpages, with an estimated 5% of pages before 2021 containing hate speech or slurs. As of 2024, Common Crawl had been cited in more than 10,000 academic studies. By 2024, The Pile and Common Crawl had been the two main training datasets being used to train AI models. In November 2025, an investigation by technology journalist Alex Reisner for The Atlantic revealed that Common Crawl misled publishers when it claimed it respected paywalls in its scraping and when it said that it was honoring requests from publishers to have their content removed from its databases. It included misleading results in the public search function on its website that showed no entries for websites that had requested their archives be removed, when in fact those sites were still included in its scrapes used by AI companies. As of 2025, Reisner found that CCBot was the most widely-blocked bot by the top 1000 websites. A 2026 article in LWN.net discussed an advantage to services like Common Crawl being that it can limit the scraping costs to websites by allowing companies and researchers to download the data from Common Crawl instead of scraping it themselves. In April 2026, Common Crawl experimentally began to distribute its data through Hugging Face Storage Bucket, in addition to its standard storage on Amazon S3. == Organization == Peter Norvig and Joi Ito have served on the advisory board. Rich Skrenta is the executive director. It has received funding almost exclusively from the Elbaz Family Foundation Trust until 2023 when it started receiving donations from the AI industry. == Refined versions == A number of organizations take raw Common Crawl data and refine it into datasets that exclude edgy content or are otherwise higher-quality for their purposes, such as FineWeb, DCLM and C4. === Colossal Clean Crawled Corpus === Google version of the Common Crawl is called the Colossal Clean Crawled Corpus, or C4 for short. It was constructed for the training of the T5 language model series in 2019. As of 2023, there were some concerns over copyrighted content in the C4 as well as racist content. A 2024 study found that 45% of content was explicitly restricted by websites' terms of service to be used for purposes like AI training by for-profit companies.

Objective vision

Objective Vision (Object Oriented Visionary) is a project mainly aimed at real-time computer vision and simulation vision of living creatures. it has three sections containing an open-source library of programming functions for using inside the projects, Virtual laboratory for scholars to check the application of functions directly and by command-line code for external and instant access, and the research section consists of paperwork and libraries to expand the scientific prove of works. == Background == The process has been used in the OVC libraries is as same as what's happening when living see a picture, and it's designed to give the researchers to experience the brain's visual cortex most close simulation for picture perception. The OVC was designed to work as a simulated visual cortex that has a critical job in processing and classify the objects to make it easier to work with pictures and graphical perception and processing. The human brain is much more aware of how it solves complex problems such as playing chess or solving algebra equations, which is why computer programmers have had so much success building machines that emulate this type of activity. but when the whole process is still a riddle that how the entities visionary system works. The project was simulated the visionary system by how it starts to convert the signals to image(actually the edges and colors) and then recognizing the shapes to find a relation between brain's information and image. The Objective Visionary system actually is concentrating on the separable sections, this separation gives the application visionary system the excellence processing result, because with this method the system do not waste much time on processing non significant sections and signals. this operation in the Objective Vision project called objective processing and because the O.V. mission is focused on human visionary simulation, so the developer refers with Objective Vision. == History == Objective-Vision is a Human (Natural) Visionary simulation Project developed by Michael Bidollahkhany. Following an explosion of interest during the 21st century were characterized by the maturing of the field and the significant growth of active applications; simulation of visionary systems, visionary based autonomous vehicle guidance, medical imaging (2D and 3D) and automatic surveillance are the most rapidly developing areas. This progress can be seen in an increasing number of software and hardware products on the market, as well as in a number of digital image processing software and APIs and also machine vision courses offered at universities worldwide. Therefore, the OVC project has been released as a research software project in 2016. One of important parts of this project was O.V.C. (Objective Vision Class library), that was designed to able companies and scientists to use the brain's most likely functionalities as visionary libraries to simplify and accelerate the image processing algorithms developments. The project started under MIT copyright license, but since 2018 the project continued as classified based on sponsors opinion. == The Algorithm == As developers claimed the algorithm used in the class library and developer's kit of project has been developed based on natural visionary system, and the functionalities containing image processing, optimization and labeling etc. are mostly upgraded and near techniques. Suppose that we've a picture of a jungle, or somewhere else, with this library developer will be able to manipulate not only the pixel of images for data extraction, but automatically based on which algorithm is used and image quality, he can manipulate directly a list of objects, same pixels and every data project needs to have, said the developer in his lecture answering how the algorithm works. === Viewpoint === For long times digital image processing and storing, was actually by processing just pixels; this Project tries to present a new kind of image processing and even storing, "objective vision" or "object-oriented visionary" is called. This project officially launched in May 2016, with the aim of making more adaptation between Computer Vision (Include Visionary, Digital image processing, discernment and even Perception) and Human Visual System; about development of the project: "...so we decided to research on Human Vision System, besides we worked on Artificial Retinal image processing and new visionary optimization unit(Presented at Istanbul Technical University Conference(Turkey 2015-2016)) and grew our research to Visionary CORTEX of Brain", Michael Bidollahkhany said. == Applications == The OVC application areas include: 2D and 3D feature toolkits Egomotion estimation Human–computer interaction (HCI) Mobile robotics Motion understanding Object identification Segmentation and recognition Stereopsis stereo vision: depth perception from two cameras Structure from motion (SFM) Motion tracking == Programming language == In first initial release of Objective Visionary Project the algorithm has been written in C++ and C#, and the virtual laboratory has been developed in C# and Delphi. Based on developers last lecture since the second release the complete algorithm has been re-written in C# based on .Net Core 1.0 to make it easier to work on different operating systems.

AlphaFold

AlphaFold is an artificial intelligence (AI) program developed by DeepMind, a subsidiary of Alphabet, which performs predictions of protein structure. It is designed using deep learning techniques. AlphaFold 1 (2018) placed first in the overall rankings of the 13th Critical Assessment of Structure Prediction (CASP) in December 2018. It was particularly successful at predicting the most accurate structures for targets rated as most difficult by the competition organizers, where no existing template structures were available from proteins with partially similar sequences. AlphaFold 2 (2020) repeated this placement in the CASP14 competition in November 2020. It achieved a level of accuracy much higher than any other entry. It scored above 90 on CASP's global distance test (GDT) for approximately two-thirds of the proteins, a test measuring the similarity between a computationally predicted structure and the experimentally determined structure, where 100 represents a complete match. The inclusion of metagenomic data has improved the quality of the prediction of multiple sequence alignments. One of the biggest sources of the training data was the custom-built Big Fantastic Database of 65,983,866 protein families, represented as multiple sequence alignments and Hidden Markov models, covering 2,204,359,010 protein sequences from reference databases, metagenomes, and metatranscriptomes. AlphaFold 2's results at CASP14 were described as "astounding" and "transformational". However, some researchers noted that the accuracy was insufficient for a third of its predictions, and that it did not reveal the underlying mechanism or rules of protein folding for the protein folding problem, which remains unsolved. Despite this, the technical achievement was widely recognized. On 15 July 2021, the AlphaFold 2 paper was published in Nature as an advance access publication alongside open source software and a searchable database of species proteomes. As of November 2025, the paper had been cited nearly 43,000 times. AlphaFold 3 was announced on 8 May 2024. It can predict the structure of complexes created by proteins with DNA, RNA, various ligands, and ions. The new prediction method shows a minimum 50% improvement in accuracy for protein interactions with other molecules compared to existing methods. Demis Hassabis and John Jumper shared one half of the 2024 Nobel Prize in Chemistry, awarded "for protein structure prediction," while the other half went to David Baker "for computational protein design." Hassabis and Jumper had previously won the Breakthrough Prize in Life Sciences and the Albert Lasker Award for Basic Medical Research in 2023 for their leadership of the AlphaFold project. == Background == Proteins consist of chains of amino acids which spontaneously fold to form the three dimensional (3-D) structures of the proteins. The 3-D structure is crucial to understanding the biological function of the protein. Protein structures can be determined experimentally through techniques such as X-ray crystallography, cryo-electron microscopy and nuclear magnetic resonance (NMR), which are all expensive and time-consuming. Such efforts, using the experimental methods, have identified the structures of about 170,000 proteins over the last 60 years, while there are over 200 million known proteins across all life forms. Over the years, researchers have applied numerous computational methods to predict the 3D structures of proteins from their amino acid sequences, accuracy of such methods in best possible scenario is close to experimental techniques (NMR) by the use of homology modeling based on molecular evolution. CASP, which was launched in 1994 to challenge the scientific community to produce their best protein structure predictions, found that GDT scores of only about 40 out of 100 can be achieved for the most difficult proteins by 2016. AlphaFold started competing in the 2018 CASP using an artificial intelligence (AI) deep learning technique. == Algorithm == DeepMind is known to have trained the program on over 170,000 protein structures from the Protein Data Bank, a public repository of protein sequences and structures. The program uses a form of attention network, a deep learning technique that focuses on having the AI identify parts of a larger problem, then piece it together to obtain the overall solution. The overall training was conducted on processing power between 100 and 200 GPUs. === AlphaFold 1 (2018) === AlphaFold 1 (2018) was built on work developed by various teams in the 2010s, work that looked at the large databases of related protein sequences now available from many different organisms (most without known 3D structures), to try to find changes at different residues (peptides) that appeared to be correlated, even though the residues were not consecutive in the main chain. Such correlations suggest that the residues may be close to each other physically, even though not close in the sequence, allowing a contact map to be estimated. Building on recent work prior to 2018, AlphaFold 1 extended this by estimating a probability distribution for the distances between residues, effectively transforming the contact map into a distance map. It also used more advanced learning methods than previously to develop the inference. The code was not made publicly available, except to run on sequences of proteins in the 2018 CASP competition. === AlphaFold 2 (2020) === The 2020 version of the program (AlphaFold 2, 2020) is significantly different from the original version that won CASP 13 in 2018, according to the team at DeepMind. AlphaFold 1 used a number of separately trained modules to produce a guide potential, which was then combined with a physics-based energy potential. AlphaFold 2 replaced this with a system of interconnected sub-networks, forming a single, differentiable, end-to-end model based on pattern recognition. This model was trained in an integrated manner. After the neural network's prediction converges, a final refinement step applies local physical constraints using energy minimization based on the AMBER force field. This step only slightly adjusts the predicted structure. A key part of the 2020 system are two modules, believed to be based on a transformer design, which are used to progressively refine a vector of information for each relationship (or "edge" in graph-theory terminology) between an amino acid residue of the protein and another amino acid residue (these relationships are represented by the array shown in green); and between each amino acid position and each different sequences in the input sequence alignment (these relationships are represented by the array shown in red). Internally these refinement transformations contain layers that have the effect of bringing relevant data together and filtering out irrelevant data (the "attention mechanism") for these relationships, in a context-dependent way, learned from training data. These transformations are iterated, the updated information output by one step becoming the input of the next, with the sharpened residue/residue information feeding into the update of the residue/sequence information, and then the improved residue/sequence information feeding into the update of the residue/residue information. As the iteration progresses, according to one report, the "attention algorithm ... mimics the way a person might assemble a jigsaw puzzle: first connecting pieces in small clumps—in this case clusters of amino acids—and then searching for ways to join the clumps in a larger whole." The output of these iterations then informs the final structure prediction module, which also uses transformers, and is itself then iterated. In an example presented by DeepMind, the structure prediction module achieved a correct topology for the target protein on its first iteration, scored as having a GDT_TS of 78, but with a large number (90%) of stereochemical violations – i.e. unphysical bond angles or lengths. With subsequent iterations the number of stereochemical violations fell. By the third iteration the GDT_TS of the prediction was approaching 90, and by the eighth iteration the number of stereochemical violations was approaching zero. The training data was originally restricted to single peptide chains. However, the October 2021 update, named AlphaFold-Multimer, included protein complexes in its training data. DeepMind stated this update succeeded about 70% of the time at accurately predicting protein-protein interactions. === AlphaFold 3 (2024) === Announced on 8 May 2024, AlphaFold 3 was co-developed by Google DeepMind and Isomorphic Labs, both subsidiaries of Alphabet. AlphaFold 3 is not limited to proteins, as it can also predict the structures of protein complexes with DNA, RNA, post-translational modifications and selected ligands and ions. AlphaFold 3 introduces the "Pairformer," a deep learning architecture inspired by the transformer, which is considered similar to, but si