Regina Barzilay (Hebrew: רגינה ברזילי; born 1970) is an Israeli-American computer scientist. She is a professor at the Massachusetts Institute of Technology and a faculty lead for artificial intelligence at the MIT Jameel Clinic. Her research interests are in natural language processing and applications of deep learning to chemistry and oncology. == Early life and education == Barzilay was born in Chișinău, Moldova and emigrated to Israel with her parents at the age of 20. She received bachelor's and master's degrees from Ben-Gurion University of the Negev in 1993 and 1998, respectively. She obtained a PhD in computer science from Columbia University in 2003 for research supervised by Kathleen McKeown. == Career and research == After her PhD, she spent a year as a postdoctoral researcher at Cornell University. She was appointed as Delta Electronics Professor of Electrical Engineering and Computer Science at MIT in 2016. She was diagnosed with breast cancer in 2014, which prompted her to conduct research in oncology. Barzilay won the MacArthur Fellowship in 2017. For her doctoral dissertation at Columbia University, she led the development of Newsblaster, which recognized stories from different news sources as being about the same basic subject, and then paraphrased elements from the stories to create a summary. In computational linguistics, Barzilay created algorithms that learned annotations from common languages (i.e. English) to analyze less understood languages. Prompted by her experience with breast cancer, Barzilay is applying machine learning to oncology. She is collaborating with physicians and students to devise deep learning models that utilize images, text, and structured data to identify trends that affect early diagnosis, treatment, and disease prevention. Frontline Documentary Following her battle with breast cancer in 2014, and her researching into applying artificial intelligence to improve early detection methods, she collaborated with Dr. Connie Lehman at Massachusetts General Hospital. While there Barzilay developed an AI-based system capable of predicting the likelihood of breast cancer up to five years in advance. The system leverages deep learning techniques to analyze mammograms and diagnostic notes, surpassing traditional pattern recognition by human radiologists. This breakthrough, while still in development, has the potential to significantly enhance early diagnosis and treatment outcomes. [1] Barzilay's work in this area was featured in the FRONTLINE documentary In the Age of AI, which explores the broader impact of artificial intelligence on society. === MIT Jameel Clinic === In 2018, Barzilay was appointed faculty lead for AI at the new MIT Jameel Clinic, a research center in the field of AI health sciences, including disease detection, drug discovery, and the development of medical devices. In 2020, she was part of the team—with fellow MIT Jameel Clinic faculty lead Professor James J. Collins—that announced the discovery through deep learning of halicin, the first new antibiotic compound for 30 years, which kills over 35 powerful bacteria, including antimicrobial-resistant tuberculosis, the superbug C. difficile, and two of the World Health Organization's top-three most deadly bacteria. In 2020, Collins, Barzilay and the MIT Jameel Clinic were also awarded funding through The Audacious Project to expand on the discovery of halicin in using AI to respond to the antibiotic resistance crisis through the development of new classes of antibiotics. == Awards and recognition == In 2017, Barzilay won the MacArthur Fellowship, known as the "Genius Grant", for "developing machine learning methods that enable computers to process and analyze vast amounts of human language data." She is also a recipient of various awards including the NSF Career Award, the MIT Technology Review TR-35 Award, Microsoft Faculty Fellowship and several Best Paper Awards at NAACL and ACL. Her teaching has also been recognized by MIT as she won the Jamieson Teaching Award in 2016. She was nominated an AAAI Fellow in 2018 by the Association for the Advancement of Artificial Intelligence. In 2020, she became the first recipient of the $1 million AAAI Squirrel AI Award for Artificial Intelligence for the Benefit of Humanity. In 2023, she was elected to the National Academy of Medicine and the National Academy of Engineering.
Cloem
Cloem is a company based in Cannes, France, which applies natural language processing (NLP) technologies to assist patent applicants in creating variants of patent claims, called "cloems". According to the company, these "computer-generated claims can be published to keep potential competitors from attempting to file adjacent patent claims." == Technology == According to Cloem, dictionaries, ontologies and proprietary claim-drafting algorithms are used to draft alternative claims based on a client's original set of claims. In particular, the original set of claims is subject to various permutations and linguistic manipulations "by considering alternative definitions for terms as well as “synonyms, hyponyms, hyperonyms, meronyms, holonyms, and antonyms.”" == Possible uses == Cloem can optionally publish one or more created texts, as electronic publications or as paper-printed publications. These can potentially serve – through a defensive publication – as prior art to prevent another party for obtaining a patent on the subject-matter at stake. In other words, after an initial patent filing, an "improvement" patent (adjacent invention) can be applied for by another party, such as a competitor. By publishing variants of a patent claim, the risk of adverse patenting may potentially be decreased (improvement inventions may no longer be patentable). Cloems may also be potentially patentable. One of the issues of patentability, however, is that only a natural person can be a listed as an inventor on a patent. Since cloems are produced by a computer based on a person's input, it is not clear if the computer or the person is the inventor. The inventorship of Cloem texts is an open question.
TinyML
TinyML (short for tiny machine learning) is an area of machine learning that focuses on deploying and running models on low-power, resource-constrained embedded systems such as microcontrollers and edge devices. TinyML supports on-device inference with low latency and minimal reliance on cloud connectivity, which makes it suitable for applications in the Internet of Things (IoT), wearable devices, and real-time systems. == History == The idea of running machine learning models on embedded systems has gained traction in the late 2010s, as model compression, quantization, and efficient neural network architectures progressed. The term TinyML was popularized in 2019 with the publication of the book TinyML by Pete Warden and Daniel Situnayake and the creation of the TinyML Foundation.
Similarity learning
Similarity learning is an area of supervised machine learning in artificial intelligence. It is closely related to regression and classification, but the goal is to learn a similarity function that measures how similar or related two objects are. It has applications in ranking, in recommendation systems, visual identity tracking, face verification, and speaker verification. == Learning setup == There are four common setups for similarity and metric distance learning. Regression similarity learning In this setup, pairs of objects are given ( x i 1 , x i 2 ) {\displaystyle (x_{i}^{1},x_{i}^{2})} together with a measure of their similarity y i ∈ R {\displaystyle y_{i}\in R} . The goal is to learn a function that approximates f ( x i 1 , x i 2 ) ∼ y i {\displaystyle f(x_{i}^{1},x_{i}^{2})\sim y_{i}} for every new labeled triplet example ( x i 1 , x i 2 , y i ) {\displaystyle (x_{i}^{1},x_{i}^{2},y_{i})} . This is typically achieved by minimizing a regularized loss min W ∑ i l o s s ( w ; x i 1 , x i 2 , y i ) + r e g ( w ) {\displaystyle \min _{W}\sum _{i}loss(w;x_{i}^{1},x_{i}^{2},y_{i})+reg(w)} . Classification similarity learning Given are pairs of similar objects ( x i , x i + ) {\displaystyle (x_{i},x_{i}^{+})} and non similar objects ( x i , x i − ) {\displaystyle (x_{i},x_{i}^{-})} . An equivalent formulation is that every pair ( x i 1 , x i 2 ) {\displaystyle (x_{i}^{1},x_{i}^{2})} is given together with a binary label y i ∈ { 0 , 1 } {\displaystyle y_{i}\in \{0,1\}} that determines if the two objects are similar or not. The goal is again to learn a classifier that can decide if a new pair of objects is similar or not. Ranking similarity learning Given are triplets of objects ( x i , x i + , x i − ) {\displaystyle (x_{i},x_{i}^{+},x_{i}^{-})} whose relative similarity obey a predefined order: x i {\displaystyle x_{i}} is known to be more similar to x i + {\displaystyle x_{i}^{+}} than to x i − {\displaystyle x_{i}^{-}} . The goal is to learn a function f {\displaystyle f} such that for any new triplet of objects ( x , x + , x − ) {\displaystyle (x,x^{+},x^{-})} , it obeys f ( x , x + ) > f ( x , x − ) {\displaystyle f(x,x^{+})>f(x,x^{-})} (contrastive learning). This setup assumes a weaker form of supervision than in regression, because instead of providing an exact measure of similarity, one only has to provide the relative order of similarity. For this reason, ranking-based similarity learning is easier to apply in real large-scale applications. Locality sensitive hashing (LSH) Hashes input items so that similar items map to the same "buckets" in memory with high probability (the number of buckets being much smaller than the universe of possible input items). It is often applied in nearest neighbor search on large-scale high-dimensional data, e.g., image databases, document collections, time-series databases, and genome databases. A common approach for learning similarity is to model the similarity function as a bilinear form. For example, in the case of ranking similarity learning, one aims to learn a matrix W that parametrizes the similarity function f W ( x , z ) = x T W z {\displaystyle f_{W}(x,z)=x^{T}Wz} . When data is abundant, a common approach is to learn a siamese network – a deep network model with parameter sharing. == Metric learning == Similarity learning is closely related to distance metric learning. Metric learning is the task of learning a distance function over objects. A metric or distance function has to obey four axioms: non-negativity, identity of indiscernibles, symmetry and subadditivity (or the triangle inequality). In practice, metric learning algorithms ignore the condition of identity of indiscernibles and learn a pseudo-metric. When the objects x i {\displaystyle x_{i}} are vectors in R d {\displaystyle R^{d}} , then any matrix W {\displaystyle W} in the symmetric positive semi-definite cone S + d {\displaystyle S_{+}^{d}} defines a distance pseudo-metric of the space of x through the form D W ( x 1 , x 2 ) 2 = ( x 1 − x 2 ) ⊤ W ( x 1 − x 2 ) {\displaystyle D_{W}(x_{1},x_{2})^{2}=(x_{1}-x_{2})^{\top }W(x_{1}-x_{2})} . When W {\displaystyle W} is a symmetric positive definite matrix, D W {\displaystyle D_{W}} is a metric. Moreover, as any symmetric positive semi-definite matrix W ∈ S + d {\displaystyle W\in S_{+}^{d}} can be decomposed as W = L ⊤ L {\displaystyle W=L^{\top }L} where L ∈ R e × d {\displaystyle L\in R^{e\times d}} and e ≥ r a n k ( W ) {\displaystyle e\geq rank(W)} , the distance function D W {\displaystyle D_{W}} can be rewritten equivalently D W ( x 1 , x 2 ) 2 = ( x 1 − x 2 ) ⊤ L ⊤ L ( x 1 − x 2 ) = ‖ L ( x 1 − x 2 ) ‖ 2 2 {\displaystyle D_{W}(x_{1},x_{2})^{2}=(x_{1}-x_{2})^{\top }L^{\top }L(x_{1}-x_{2})=\|L(x_{1}-x_{2})\|_{2}^{2}} . The distance D W ( x 1 , x 2 ) 2 = ‖ x 1 ′ − x 2 ′ ‖ 2 2 {\displaystyle D_{W}(x_{1},x_{2})^{2}=\|x_{1}'-x_{2}'\|_{2}^{2}} corresponds to the Euclidean distance between the transformed feature vectors x 1 ′ = L x 1 {\displaystyle x_{1}'=Lx_{1}} and x 2 ′ = L x 2 {\displaystyle x_{2}'=Lx_{2}} . Many formulations for metric learning have been proposed. Some well-known approaches for metric learning include learning from relative comparisons, which is based on the triplet loss, large margin nearest neighbor, and information theoretic metric learning (ITML). In statistics, the covariance matrix of the data is sometimes used to define a distance metric called Mahalanobis distance. == Applications == Similarity learning is used in information retrieval for learning to rank, in face verification or face identification, and in recommendation systems. Also, many machine learning approaches rely on some metric. This includes unsupervised learning such as clustering, which groups together close or similar objects. It also includes supervised approaches like K-nearest neighbor algorithm which rely on labels of nearby objects to decide on the label of a new object. Metric learning has been proposed as a preprocessing step for many of these approaches. == Scalability == Metric and similarity learning scale quadratically with the dimension of the input space, as can easily see when the learned metric has a bilinear form f W ( x , z ) = x T W z {\displaystyle f_{W}(x,z)=x^{T}Wz} . Scaling to higher dimensions can be achieved by enforcing a sparseness structure over the matrix model, as done with HDSL, and with COMET. == Software == metric-learn is a free software Python library which offers efficient implementations of several supervised and weakly-supervised similarity and metric learning algorithms. The API of metric-learn is compatible with scikit-learn. OpenMetricLearning is a Python framework to train and validate the models producing high-quality embeddings. == Further information == For further information on this topic, see the surveys on metric and similarity learning by Bellet et al. and Kulis.
Hidden layer
In artificial neural networks, a hidden layer is a layer of artificial neurons that is neither an input layer nor an output layer. The simplest examples appear in multilayer perceptrons (MLP), as illustrated in the diagram. An MLP without any hidden layer is essentially just a linear model. With hidden layers and activation functions, however, nonlinearity is introduced into the model. In typical machine learning practice, the weights and biases are initialized, then iteratively updated during training via backpropagation.
GOLOG
GOLOG is a high-level logic programming language for the specification and execution of complex actions in dynamical domains. It is based on the situation calculus. It is a first-order logical language for reasoning about action and change. GOLOG was developed at the University of Toronto. == History == The concept of situation calculus on which the GOLOG programming language is based was first proposed by John McCarthy in 1963. == Description == A GOLOG interpreter automatically maintains a direct characterization of the dynamic world being modeled, on the basis of user supplied axioms about preconditions, effects of actions and the initial state of the world. This allows the application to reason about the condition of the world and consider the impacts of different potential actions before focusing on a specific action. Golog is a logic programming language and is very different from conventional programming languages. A procedural programming language like C defines the execution of statements in advance. The programmer creates a subroutine which consists of statements, and the computer executes each statement in a linear order. In contrast, fifth-generation programming languages like Golog work with an abstract model with which the interpreter can generate the sequence of actions. The source code defines the problem and it is up to the solver to find the next action. This approach can facilitate the management of complex problems from the domain of robotics. A Golog program defines the state space in which the agent is allowed to operate. A path in the symbolic domain is found with state space search. To speed up the process, Golog programs are realized as hierarchical task networks. Apart from the original Golog language, there are some extensions available. The ConGolog language provides concurrency and interrupts. Other dialects like IndiGolog and Readylog were created for real time applications in which sensor readings are updated on the fly. == Uses == Golog has been used to model the behavior of autonomous agents. In addition to a logic-based action formalism for describing the environment and the effects of basic actions, they enable the construction of complex actions using typical programming language constructs. It is also used for applications in high level control of robots and industrial processes, virtual agents, discrete event simulation etc. It can be also used to develop Belief Desire Intention-style agent systems. == Planning and scripting == In contrast to the Planning Domain Definition Language, Golog supports planning and scripting as well. Planning means that a goal state in the world model is defined, and the solver brings a logical system into this state. Behavior scripting implements reactive procedures, which are running as a computer program. For example, suppose the idea is to authoring a story. The user defines what should be true at the end of the plot. A solver gets started and applies possible actions to the current situation until the goal state is reached. The specification of a goal state and the possible actions are realized in the logical world model. In contrast, a hardwired reactive behavior doesn't need a solver but the action sequence is provided in a scripting language. The Golog interpreter, which is written in Prolog, executes the script and this will bring the story into the goal state.
Connectionist expert system
Connectionist expert systems are artificial neural network (ANN) based expert systems where the ANN generates inferencing rules e.g., fuzzy-multi layer perceptron where linguistic and natural form of inputs are used. Apart from that, rough set theory may be used for encoding knowledge in the weights better and also genetic algorithms may be used to optimize the search solutions better. Symbolic reasoning methods may also be incorporated (see hybrid intelligent system). (Also see expert system, neural network, clinical decision support system.)