A coronavirus breathalyzer is a diagnostic medical device enabling the user to test with 90% or greater accuracy the presence of severe acute respiratory syndrome coronavirus 2 in an exhaled breath. As of the first half of 2020, the idea of a practical coronavirus breathalyzer was concomitantly developed by unrelated research groups in Australia, Canada, Finland, Germany, Indonesia, Israel, Netherlands, Poland, Singapore, United Kingdom and the USA. == Australia == In Australia, GreyScan CEO Samantha Ollerton and Prof. Michael Breadmore of the University of Tasmania are basing a coronavirus breathalyzer on existing technology that is used around the world to detect explosives. Another invention published from ABC News; produced by Colin Hickey and Examin Holdings, have released information on a new breathalyzer called the "Queensland Breath test" claiming its function has 98% efficiency, equipped with a replaceable plastic nozzle for reusability (February 2022). a statement in claim by Bruce Thompson, a professor at Swinburne University of Technology, Although this products is reliable, due to insufficient funding, the product is inaccessible. == Canada == Canary Health Technologies, headquartered in Toronto with offices in Cleveland, Ohio, is developing a breathalyzer with disposable nanosensors using AI-powered cloud-based analysis. According to a press release, clinical trials began in India during November 2020. The stated goal is to develop an accurate, reasonably priced screening tool that can be used anywhere and deliver a result in less than a minute. The company postulates that analyzing volatile organic compounds in human breath could potentially detect diseases before the on-set of symptoms, earlier than currently available methods. Moreover, the cloud-based technology is designed to be used as a disease surveillance apparatus. == Finland == By the end of June 2020, Forum Virium Helsinki, in collaboration with Finnish software firm Deep Sensing Algorithms, funded by the Helsinki-Uusimaa Regional Council, announced that testing of their device had begun with a control group in Kazakhstan, with plans to expand to the Netherlands, the United States, South Africa, Brazil and Finland throughout the summer. The efficacy of the Forum Virium Helsinki / Deep Sensing Algorithms device hinges on its AI component. "We are engaged in innovative cooperation with corporations to solve the coronavirus crisis, and we will help firms to use the city as a development platform. We are utilizing artificial intelligence and digitalization," said Forum Virium Helsinki CEO Mika Malin. == Germany == In March 2020, the Singaporean company RAM Global conducted research in Germany in hopes of developing a one-minute breathalyzer test for SARS-CoV-2 based on terahertz time-domain spectroscopy. The company attempted to develop a disposable test kit for direct detection of COVID-19 virion particles in breath, saliva and swab samples. On 31 March, RAM Global completed an initial clinical study on live patients at University Hospital Saarland. In April, the company pursued a small unknown sample study in which hospital doctors provided unknown samples in order to test accuracy in differentiating positive and negative samples. == Indonesia == Since April 2020, a team of researchers from Gadjah Mada University (UGM) has been developing an electronic nose called GeNose C19. The GeNose C19 can be used as a rapid, non-invasive screening tool in less than two minutes. A profiling test was carried out at the Bhayangkara Hospital and the Covid Bambanglipuro Special Field Hospital in Yogyakarta. GeNose C19 consists of gas sensors and an artificial intelligence-based pattern recognition system. The diagnostic test was carried out with the cooperation of nine multi-center hospitals. In the end of December 2020, GeNose C19 received a distribution permit from Indonesia's Health Ministry. Initially, 100 units will be released and each device will be able to perform 120 tests per day. The test is estimated to cost 15,000–25,000 Indonesian rupiah ($1–$1.8) and would take three minutes for the test and another two minutes to yield a result. Researchers hope to manufacture up to 1,000 GeNose C19 units, increasing the country's testing capabilities by 120 thousand subjects per day. Moreover, they aim to manufacture 10,000 units by February 2021. == Israel == In Israel, it is at the photonics lab of Gabby Sarusi, professor at Ben-Gurion University of the Negev, that research is underway as of midsummer 2020. Separately from Sarusi's project, in July 2020, it was reported that Israeli start-up Nanoscent in cooperation with Sheba Medical Center had devised a breathalyzer that Magen David Adom (MDA) is seeking to incorporate into existing drive-thru testing stations located throughout the country. Questionable intellectual property of Gabby Sarusi regarding this project is now under discussion in the court in Israel. == The Netherlands == A breath test with the SpiroNose device, made by the Dutch company Breathomix, has been developed and tested in collaboration with the Leiden University Medical Center (LUMC), Franciscus Gasthuis & Vlietland and the GGD Amsterdam. The breath test has been validated as a pre-screening test for people who have no or mild symptoms of COVID-19. From April 2021, the device was operational in COVID-19 test drive-ins, conferences and events, i.e. Eurovision Song Contest 2021. Subjects must abstain from alcohol for eight hours prior to taking the breath test. The SpiroNose contains four sets of seven different sensors that can measure the mixture of volatile organic compounds (biomarkers) in the exhaled air. These VOCs provide a picture of a person's metabolism. This 'breath profile' is forwarded to an online analysis platform. Here the breath profile is compared with other breath profiles of people with and without a COVID-19 diagnosis and analysed by algorithms. Data-analysis involves advanced signal processing and statistics based on independent t-tests followed by linear discriminant and ROC analysis. The test result is known within minutes. The breath test has a sensitivity/specificity for SARS-CoV-2 infection of 100/78, >99/84, 98/82% in validation, replication and asymptomatic cohorts of patients. The breath test reliably detects who is not infected. Such a subject will receive a test result immediately. Other subjects must promptly conduct a subsequent test, for example a PCR test or LAMP test. The test results can be viewed by the client and are not automatically interfaced to other databases, i.e. for public health surveillance, source and contact tracing, vaccination programs. In July 2021, the ministry stopped the tests with the SpiroNose because, according to the GGD, the device gives unusable results in some cases. Breathomix indicates that this is the result of the way in which the SpiroNose is deployed. The SpiroNose is and remains a reliable instrument for lung diseases. The analysis platform is developed conform the requirements of the standard ISO 27001 (Information Security) and NEN 7510 (Information Security in Health Care). A CE marking has been requested. In the meantime, the Dutch minister has granted a CE marking exemption on 25 January 2021. The device may also be used to detect other diseases, e.g., asthma, COPD, lung cancer, interstitial lung diseases (ILD). == Poland == In February 2021, the President of Poland, Andrzej Duda, announced that ML System S. A., headquartered in Zaczernie, Poland, had successfully developed a means of analyzing a patient's breath to test for the presence of coronavirus. According to an anonymous press release, test subjects exhale into a device in order to determine the presence of the coronavirus. The procedure, similar to that of a police breathalyzer, is said to take less than ten seconds. Independent clinical trials were begun in April 2021. In the first half of May 2021, a brief text concerning partial results was published by ML System, stating that independent clinical trials were successful with specificity (97,15%) and accuracy/sensitivity (86,86%), for CT (Cycle Threshold) assumed at 25, which is in line with the guidelines set out by the World Health Organization. Moreover, ML System in partnership with Rzeszów–Jasionka Airport published a statement indicating their intention to test the device at the airport. Similar plans exist between the manufacturer and the Warsaw Chopin Airport. Two large networks of laboratories in Poland, "Diagnostyka" and "ALAB Laboratoria", have signed a letter of intent with ML System. In agreement with ALAB, the parties declared cooperation in the implementation of the product named "COVID DETECTOR" on the Polish, German and Ukrainian markets. In addition, the companies declared joint activities aimed at extending the diagnosis with the use of "COVID Detector" to include mutations of the SARS-CoV-2 virus, differentiate the stage of the disease and ot
Verbot
The Verbot (short for Verbal-Robot) was a chatbot program and artificial intelligence software development kit (SDK) designed for Windows and web platforms. == Early beginning == The origin of verbot traces back to Michael Mauldin's research during his time as a graduate student and post-doctoral fellow at Carnegie Mellon University. The creative foundation also stems from Peter Plantec's work in personality psychology and art direction. === Historic outline === In 1994, Michael Loren Mauldin, founder of Lycos, Inc., developed a prototype chatbot, Julia, which competed in the internationally known Turing test, for the coveted Loebner Prize. The Turing test matches computer scientist judges against machines to see if they can distinguish a computer from a real human. Julia was refined and developed, and in 1997, Dr. Mauldin and Peter Plantec, a clinical psychologist and animator, formed Virtual Personalities, Inc. (now Conversive, Inc.) in order to create a virtual human interface that would incorporate real-time animation as well as speech and natural language processing. The initial release, a stand-alone virtual person called Sylvie, was beta-tested to the public. This release was well received, and finally, after several versions, the production release (deemed version 3) of the Verbally Enhanced Software Robot, or Verbot, was deployed in fall 2000. The grandfather of all Verbots is Rog-O-Matic, which, although it could not talk, could and did explore a virtual world. Julia has been active on the internet in one form or another since 1989. A close cousin of Julia is Lycos, a robot that explores the World Wide Web and answers questions about it. Sylvie was the first Verbot with a face and a voice. Sylvie was the first Virtual Human with advanced, flexible interfacing capability. === Beginnings === The Virtual Personalities story goes back to 1978, where Mauldin was attending Rice University. Fascinated by the idea of ELIZA, he proceeded to write a program called "PET" for his 8 kilobyte Commodore PET Computer. PET included simple induction as a way to post new information, for example: Subject: I like my friend (later) Subject: I like food. PET: I have heard that food is your friend. Meanwhile, Plantec was separately designing a personality for "Entity", a theoretical virtual human that would interact comfortably with humans without pretending to be one. At that time the technology was not advanced enough to realize Entity. Mauldin got so involved with this that he majored in Computer Science and minored in Linguistics. === Rogue === In the late seventies and early eighties, a popular computer game at universities was Rogue, an implementation of Dungeons and Dragons where the player would descend 26 levels in a randomly created dungeon, fighting monsters, gathering treasure, and searching for the elusive "Amulet of Yendor". Mauldin was one of four grad students who devoted a large amount of time to building a program called "Rog-O-Matic" capable of retrieving the amulet and emerging victorious from the dungeon. === TinyMUD === In 1989, when James Aspnes at Carnegie Mellon created the first TinyMUD (a descendant of MUD and AberMUD), Mauldin was one of the first to create a computer player that would explore the text-based world of TinyMUD. But his first robot, Gloria, gradually accreted more and more linguistic ability, to the point that it could pass the "unsuspecting" Turing test. In this version of the test, the human has no reason to suspect that one of the other occupants of the room is controlled by a computer, and so is more polite and asks fewer probing questions. The second generation of Mauldin's TinyMUD robots was Julia, created on Jan. 8, 1990. Julia slowly developed into a more and more capable conversational agent, and assumed useful duties in the TinyMUD world, including tour guide, information assistant, note-taker, and message-relayer. She could even play the card game hearts along with the other human players. In 1991, Julia attended the first Loebner Prize contest in Boston, Massachusetts. Although she only finished third, she was ranked by one judge as more human than one of the human confederates, winning a coveted certificate of humanness in the world's first restricted Turing test. Julia continued to log in to various TinyMUD's and TinyMucks for the next seven years, and chatted with hundreds of people a month over the internet. === Lycos === Julia's job was to explore a virtual world consisting of pages of textual descriptions, with links between them, and to construct an internal map of that world and answer questions about it (including path information such as the shortest route from one room to another, and matching information, such as which rooms contained a certain kind of object or textual description). It was therefore only a very short cognitive leap from Julia to Lycos, another robotic agent that explores a virtual world made of hyperlinked pages of text, and which answers questions about those pages. Sylvie was born and her abilities were expanded greatly to include interfacing with computers and control systems via her serial ports. === Sylvie === Sylvie was the first intelligent animated virtual human. She was designed both as a conversation agent and as a virtual human interface that would form a bridge between the two. She became more popular as a conversation agent, but her designers believe she serves as a prototype for future virtual human interface design that will help us all cope with the increasing complexity of technology. As an aside, Plantec noticed that a large number of Sylvies have been sold in Southeast Asia. Upon investigation, he found out that students had discovered a "test" mode that would allow them to type in English sentences that Sylvie would pronounce in her somewhat stylized English. == Ownership == In 1997, Dr. Mauldin and Peter Plantec formed Virtual Personalities, Inc. to create Natural Language Processing solutions for companies. In 2001 Virtual Personalities, Inc. became Conversive, Inc. to reflect the focus on providing Customer Service and Marketing to the Enterprise Market. In late 2012 Avaya, Inc. acquired Conversive's assets including Verbots. == Verbot versions == The Verbot 4 version was created and released in 2004. In 2005 Version 4.1 of the Verbot Software was released with many feature enhancements and bug fixes, including built-in support for embedding C# code in outputs and conditionals. In early 2006 Conversive launched Verbots Online allowing Verbot 4 users to upload their knowledge and show off their bots to the world. In 2009 Version 5 was released, completely free and fully featured. In early 2012 the last version of Verbot, 5.0.1.2, was released to the general public with support for Windows 7. Later in 2012 Verbots Online completely shut down. == Verbots today == Verbots.com, its community of users, and its forums no longer exist, but the software and users can still be found. There has been no active development since the early 2012 release of Verbot 5.0.1.2.
GNU Octave
GNU Octave is a scientific programming language for scientific computing and numerical computation. Among other things, Octave can be used to solve linear and nonlinear problems numerically and to perform other numerical experiments using a language that is mostly compatible with MATLAB. It may also be used as a batch-oriented language. As part of the GNU Project, it is free software under the terms of the GNU General Public License. == History == The project was conceived around 1988. At first it was intended to be a companion to a chemical reactor design course. Full development was started by John W. Eaton in 1992. The first alpha release dates back to 4 January 1993 and on 17 February 1994 version 1.0 was released. Version 9.2.0 was released on 7 June 2024. The program is named after Octave Levenspiel, a former professor of the principal author. Levenspiel was known for his ability to perform quick back-of-the-envelope calculations. == Development history == == Developments == In addition to use on desktops for personal scientific computing, Octave is used in academia and industry. For example, Octave was used on a massive parallel computer at Pittsburgh Supercomputing Center to find vulnerabilities related to guessing social security numbers. Acceleration with OpenCL or CUDA is also possible with use of GPUs. == Technical details == Octave is written in C++ using the C++ standard library. Octave uses an interpreter to execute the Octave scripting language. Octave is extensible using dynamically loadable modules. Octave interpreter has an OpenGL-based graphics engine to create plots, graphs and charts and to save or print them. Alternatively, gnuplot can be used for the same purpose. Octave includes a graphical user interface (GUI) in addition to the traditional command-line interface (CLI); see #User interfaces for details. == Octave, the language == The Octave language is an interpreted programming language. It is a structured programming language (similar to C) and supports many common C standard library functions, and also certain UNIX system calls and functions. However, it does not support passing arguments by reference although function arguments are copy-on-write to avoid unnecessary duplication. Octave programs consist of a list of function calls or a script. The syntax is matrix-based and provides various functions for matrix operations. It supports various data structures and allows object-oriented programming. Its syntax is very similar to MATLAB, and careful programming of a script will allow it to run on both Octave and MATLAB. Because Octave is made available under the GNU General Public License, it may be freely changed, copied and used. The program runs on Microsoft Windows and most Unix and Unix-like operating systems, including Linux, Android, and macOS. == Notable features == === Command and variable name completion === Typing a TAB character on the command line causes Octave to attempt to complete variable, function, and file names (similar to Bash's tab completion). Octave uses the text before the cursor as the initial portion of the name to complete. === Command history === When running interactively, Octave saves the commands typed in an internal buffer so that they can be recalled and edited. === Data structures === Octave includes a limited amount of support for organizing data in structures. In this example, we see a structure x with elements a, b, and c, (an integer, an array, and a string, respectively): === Short-circuit Boolean operators === Octave's && and || logical operators are evaluated in a short-circuit fashion (like the corresponding operators in the C language), in contrast to the element-by-element operators & and |. === Increment and decrement operators === Octave includes the C-like increment and decrement operators ++ and -- in both their prefix and postfix forms. Octave also does augmented assignment, e.g. x += 5. === Unwind-protect === Octave supports a limited form of exception handling modelled after the unwind_protect of Lisp. The general form of an unwind_protect block looks like this: As a general rule, GNU Octave recognizes as termination of a given block either the keyword end (which is compatible with the MATLAB language) or a more specific keyword endblock or, in some cases, end_block. As a consequence, an unwind_protect block can be terminated either with the keyword end_unwind_protect as in the example, or with the more portable keyword end. The cleanup part of the block is always executed. In case an exception is raised by the body part, cleanup is executed immediately before propagating the exception outside the block unwind_protect. GNU Octave also supports another form of exception handling (compatible with the MATLAB language): This latter form differs from an unwind_protect block in two ways. First, exception_handling is only executed when an exception is raised by body. Second, after the execution of exception_handling the exception is not propagated outside the block (unless a rethrow( lasterror ) statement is explicitly inserted within the exception_handling code). === Variable-length argument lists === Octave has a mechanism for handling functions that take an unspecified number of arguments without explicit upper limit. To specify a list of zero or more arguments, use the special argument varargin as the last (or only) argument in the list. varargin is a cell array containing all the input arguments. === Variable-length return lists === A function can be set up to return any number of values by using the special return value varargout. For example: === C++ integration === It is also possible to execute Octave code directly in a C++ program. For example, here is a code snippet for calling rand([10,1]): C and C++ code can be integrated into GNU Octave by creating oct files, or using the MATLAB compatible MEX files. == MATLAB compatibility == Octave has been built with MATLAB compatibility in mind, and shares many features with MATLAB: % Script: myscript.m a = 5; b = a 2 % Function: myfunc.m function result = myfunc(x) result = x^2 + 3; end Matrices as fundamental data type. Built-in support for complex numbers. Powerful built-in math functions and extensive function libraries. Extensibility in the form of user-defined functions. Octave treats incompatibility with MATLAB as a bug; therefore, it could be considered a software clone, which does not infringe software copyright as per Lotus v. Borland court case. MATLAB scripts from the MathWorks' FileExchange repository in principle are compatible with Octave. However, while they are often provided and uploaded by users under an Octave compatible and proper open source BSD license, the FileExchange Terms of use prohibit any usage beside MathWorks' proprietary MATLAB. === Syntax compatibility === There are a few purposeful, albeit minor, syntax additions Archived 2012-04-26 at the Wayback Machine: Comment lines can be prefixed with the # character as well as the % character; Various C-based operators ++, --, +=, =, /= are supported; Elements can be referenced without creating a new variable by cascaded indexing, e.g. [1:10](3); Strings can be defined with the double-quote " character as well as the single-quote ' character; When the variable type is single (a single-precision floating-point number), Octave calculates the "mean" in the single-domain (MATLAB in double-domain) which is faster but gives less accurate results; Blocks can also be terminated with more specific Control structure keywords, i.e., endif, endfor, endwhile, etc.; Functions can be defined within scripts and at the Octave prompt; Presence of a do-until loop (similar to do-while in C). === Function compatibility === Many, but not all, of the numerous MATLAB functions are available in GNU Octave, some of them accessible through packages in Octave Forge. The functions available as part of either core Octave or Forge packages are listed online Archived 2024-03-14 at the Wayback Machine. A list of unavailable functions is included in the Octave function __unimplemented.m__. Unimplemented functions are also listed under many Octave Forge packages in the Octave Wiki. When an unimplemented function is called the following error message is shown: == User interfaces == Octave comes with an official graphical user interface (GUI) and an integrated development environment (IDE) based on Qt. It has been available since Octave 3.8, and has become the default interface (over the command-line interface) with the release of Octave 4.0. It was well-received by an EDN contributor, who wrote "[Octave] now has a very workable GUI" in reviewing the then-new GUI in 2014. Several 3rd-party graphical front-ends have also been developed, like ToolboX for coding education. == GUI applications == With Octave code, the user can create GUI applications. See GUI Development (GNU Octave (version 7.1.0)). Below are some examples: Button, edit control, checkboxTextboxListbox wit
Genetic representation
In computer programming, genetic representation is a way of presenting solutions/individuals in evolutionary computation methods. The term encompasses both the concrete data structures and data types used to realize the genetic material of the candidate solutions in the form of a genome, and the relationships between search space and problem space. In the simplest case, the search space corresponds to the problem space (direct representation). The choice of problem representation is tied to the choice of genetic operators, both of which have a decisive effect on the efficiency of the optimization. Genetic representation can encode appearance, behavior, physical qualities of individuals. Difference in genetic representations is one of the major criteria drawing a line between known classes of evolutionary computation. Terminology is often analogous with natural genetics. The block of computer memory that represents one candidate solution is called an individual. The data in that block is called a chromosome. Each chromosome consists of genes. The possible values of a particular gene are called alleles. A programmer may represent all the individuals of a population using binary encoding, permutational encoding, encoding by tree, or any one of several other representations. == Representations in some popular evolutionary algorithms == Genetic algorithms (GAs) are typically linear representations; these are often, but not always, binary. Holland's original description of GA used arrays of bits. Arrays of other types and structures can be used in essentially the same way. The main property that makes these genetic representations convenient is that their parts are easily aligned due to their fixed size. This facilitates simple crossover operation. Depending on the application, variable-length representations have also been successfully used and tested in evolutionary algorithms (EA) in general and genetic algorithms in particular, although the implementation of crossover is more complex in this case. Evolution strategy uses linear real-valued representations, e.g., an array of real values. It uses mostly gaussian mutation and blending/averaging crossover. Genetic programming (GP) pioneered tree-like representations and developed genetic operators suitable for such representations. Tree-like representations are used in GP to represent and evolve functional programs with desired properties. Human-based genetic algorithm (HBGA) offers a way to avoid solving hard representation problems by outsourcing all genetic operators to outside agents, in this case, humans. The algorithm has no need for knowledge of a particular fixed genetic representation as long as there are enough external agents capable of handling those representations, allowing for free-form and evolving genetic representations. === Common genetic representations === binary array integer or real-valued array binary tree natural language parse tree directed graph == Distinction between search space and problem space == Analogous to biology, EAs distinguish between problem space (corresponds to phenotype) and search space (corresponds to genotype). The problem space contains concrete solutions to the problem being addressed, while the search space contains the encoded solutions. The mapping from search space to problem space is called genotype-phenotype mapping. The genetic operators are applied to elements of the search space, and for evaluation, elements of the search space are mapped to elements of the problem space via genotype-phenotype mapping. == Relationships between search space and problem space == The importance of an appropriate choice of search space for the success of an EA application was recognized early on. The following requirements can be placed on a suitable search space and thus on a suitable genotype-phenotype mapping: === Completeness === All possible admissible solutions must be contained in the search space. === Redundancy === When more possible genotypes exist than phenotypes, the genetic representation of the EA is called redundant. In nature, this is termed a degenerate genetic code. In the case of a redundant representation, neutral mutations are possible. These are mutations that change the genotype but do not affect the phenotype. Thus, depending on the use of the genetic operators, there may be phenotypically unchanged offspring, which can lead to unnecessary fitness determinations, among other things. Since the evaluation in real-world applications usually accounts for the lion's share of the computation time, it can slow down the optimization process. In addition, this can cause the population to have higher genotypic diversity than phenotypic diversity, which can also hinder evolutionary progress. In biology, the Neutral Theory of Molecular Evolution states that this effect plays a dominant role in natural evolution. This has motivated researchers in the EA community to examine whether neutral mutations can improve EA functioning by giving populations that have converged to a local optimum a way to escape that local optimum through genetic drift. This is discussed controversially and there are no conclusive results on neutrality in EAs. On the other hand, there are other proven measures to handle premature convergence. === Locality === The locality of a genetic representation corresponds to the degree to which distances in the search space are preserved in the problem space after genotype-phenotype mapping. That is, a representation has a high locality exactly when neighbors in the search space are also neighbors in the problem space. In order for successful schemata not to be destroyed by genotype-phenotype mapping after a minor mutation, the locality of a representation must be high. === Scaling === In genotype-phenotype mapping, the elements of the genotype can be scaled (weighted) differently. The simplest case is uniform scaling: all elements of the genotype are equally weighted in the phenotype. A common scaling is exponential. If integers are binary coded, the individual digits of the resulting binary number have exponentially different weights in representing the phenotype. Example: The number 90 is written in binary (i.e., in base two) as 1011010. If now one of the front digits is changed in the binary notation, this has a significantly greater effect on the coded number than any changes at the rear digits (the selection pressure has an exponentially greater effect on the front digits). For this reason, exponential scaling has the effect of randomly fixing the "posterior" locations in the genotype before the population gets close enough to the optimum to adjust for these subtleties. == Hybridization and repair in genotype-phenotype mapping == When mapping the genotype to the phenotype being evaluated, domain-specific knowledge can be used to improve the phenotype and/or ensure that constraints are met. This is a commonly used method to improve EA performance in terms of runtime and solution quality. It is illustrated below by two of the three examples. == Examples == === Example of a direct representation === An obvious and commonly used encoding for the traveling salesman problem and related tasks is to number the cities to be visited consecutively and store them as integers in the chromosome. The genetic operators must be suitably adapted so that they only change the order of the cities (genes) and do not cause deletions or duplications. Thus, the gene order corresponds to the city order and there is a simple one-to-one mapping. === Example of a complex genotype-phenotype mapping === In a scheduling task with heterogeneous and partially alternative resources to be assigned to a set of subtasks, the genome must contain all necessary information for the individual scheduling operations or it must be possible to derive them from it. In addition to the order of the subtasks to be executed, this includes information about the resource selection. A phenotype then consists of a list of subtasks with their start times and assigned resources. In order to be able to create this, as many allocation matrices must be created as resources can be allocated to one subtask at most. In the simplest case this is one resource, e.g., one machine, which can perform the subtask. An allocation matrix is a two-dimensional matrix, with one dimension being the available time units and the other being the resources to be allocated. Empty matrix cells indicate availability, while an entry indicates the number of the assigned subtask. The creation of allocation matrices ensures firstly that there are no inadmissible multiple allocations. Secondly, the start times of the subtasks can be read from it as well as the assigned resources. A common constraint when scheduling resources to subtasks is that a resource can only be allocated once per time unit and that the reservation must be for a contiguous period of time. To achieve this in a timely manner, which is a c
Relationship square
In statistics, the relationship square is a graphical representation for use in the factorial analysis of a table individuals x variables. This representation completes classical representations provided by principal component analysis (PCA) or multiple correspondence analysis (MCA), namely those of individuals, of quantitative variables (correlation circle) and of the categories of qualitative variables (at the centroid of the individuals who possess them). It is especially important in factor analysis of mixed data (FAMD) and in multiple factor analysis (MFA). == Definition of relationship square in the MCA frame == The first interest of the relationship square is to represent the variables themselves, not their categories, which is all the more valuable as there are many variables. For this, we calculate for each qualitative variable j {\displaystyle j} and each factor F s {\displaystyle F_{s}} ( F s {\displaystyle F_{s}} , rank s {\displaystyle s} factor, is the vector of coordinates of the individuals along the axis of rank s {\displaystyle s} ; in PCA, F s {\displaystyle F_{s}} is called principal component of rank s {\displaystyle s} ), the square of the correlation ratio between the F s {\displaystyle F_{s}} and the variable j {\displaystyle j} , usually denoted : η 2 ( j , F s ) {\displaystyle \eta ^{2}(j,F_{s})} Thus, to each factorial plane, we can associate a representation of qualitative variables themselves. Their coordinates being between 0 and 1, the variables appear in the square having as vertices the points (0,0), ( 0,1), (1,0) and (1,1). == Example in MCA == Six individuals ( i 1 , … , i 6 ) {\displaystyle i_{1},\ldots ,i_{6})} are described by three variables ( q 1 , q 2 , q 3 ) {\displaystyle (q_{1},q_{2},q_{3})} having respectively 3, 2 and 3 categories. Example : the individual i 1 {\displaystyle i_{1}} possesses the category a {\displaystyle a} of q 1 {\displaystyle q_{1}} , d {\displaystyle d} of q 2 {\displaystyle q_{2}} and f {\displaystyle f} of q 3 {\displaystyle q_{3}} . Applied to these data, the MCA function included in the R Package FactoMineR provides to the classical graph in Figure 1. The relationship square (Figure 2) makes easier the reading of the classic factorial plane. It indicates that: The first factor is related to the three variables but especially q 3 {\displaystyle q_{3}} (which have a very high coordinate along the first axis) and then q 2 {\displaystyle q_{2}} . The second factor is related only to q 1 {\displaystyle q_{1}} and q 3 {\displaystyle q_{3}} (and not to q 2 {\displaystyle q_{2}} which has a coordinate along axis 2 equal to 0) and that in a strong and equal manner. All this is visible on the classic graphic but not so clearly. The role of the relationship square is first to assist in reading a conventional graphic. This is precious when the variables are numerous and possess numerous coordinates. == Extensions == This representation may be supplemented with those of quantitative variables, the coordinates of the latter being the square of correlation coefficients (and not of correlation ratios). Thus, the second advantage of the relationship square lies in the ability to represent simultaneously quantitative and qualitative variables. The relationship square can be constructed from any factorial analysis of a table individuals x variables. In particular, it is (or should be) used systematically: in multiple correspondences analysis (MCA); in principal components analysis (PCA) when there are many supplementary variables; in factor analysis of mixed data (FAMD). An extension of this graphic to groups of variables (how to represent a group of variables by a single point ?) is used in Multiple Factor Analysis (MFA) == History == The idea of representing the qualitative variables themselves by a point (and not the categories) is due to Brigitte Escofier. The graphic as it is used now has been introduced by Brigitte Escofier and Jérôme Pagès in the framework of multiple factor analysis == Conclusion == In MCA, the relationship square provides a synthetic view of the connections between mixed variables, all the more valuable as there are many variables having many categories. This representation iscan be useful in any factorial analysis when there are numerous mixed variables, active and/or supplementary.
Are You Dead?
Are You Dead? (Chinese: 死了么; pinyin: Sǐleme), also known by its English name Demumu, is a Chinese application designed for young people living alone. It requires setting up one emergency contact and sends automatic notifications if the user has not checked in via the app for consecutive days. The app was released on the App Store on 10 June 2025. In early January 2026, the application gained popularity due to its name and the issue of safety for people living alone, and ranked high on the list of paid applications in the Chinese region of the Apple App Store before being removed. The app's rise in popularity sparked discussions about taboos about death in China. == History == Are You Dead? was founded and operated independently by three people born in the 1990s, and developed in a way that involved remote collaboration in their spare time. According to the New Yellow River report, Guo, the product manager, said that the application was designed for young people and that the inspiration came from the discussion of netizens on social platforms about "an app that everyone must have and will definitely download" that he observed two or three years ago. The name was also "not their original creation". After realizing its potential demand and social significance, the team successfully registered the name and completed the product development in about a month. Regarding the development entity, the New Yellow River cited information from the Apple App Store that the application was developed by Yuejing (Zhengzhou) Technology Service Co., Ltd. According to Tianyancha information, the company was established in March 2025 with a registered capital of 100,000 yuan. === Rise in popularity === The app has been generating buzz on social media since 9 January 2026, due to its name and the topic of safety for people living alone. Around 10 January, it topped the Apple paid app chart. As of 10:00 a.m. on January 11, it ranked first in the App Store paid app chart. It also ranked highly in the utility app chart; it ranked first or second in the paid utility app charts in the United States, Singapore and Hong Kong, and first or fourth in Australia and Spain. The app was subsequently removed from the Apple App Store in China. In terms of functionality and usage, First Financial praised the product for its "simple interface and single function," but pointed out that the interface lacks a display of consecutive check-in days, and there is also the possibility that users may forget to check in, leading to the mistaken issuance of reminders. In addition, since the application mainly relies on email reminders and lacks SMS or telephone notifications, it does not conform to Chinese social habits; the untimely notifications also make the application more like a "death notification" tool, losing its early warning significance for emergency rescue. Hu Xijin, former editor-in-chief of the Global Times, commented on the application on Weibo that it is "really good and can help many lonely elderly people." The Beijing News Quick Review pointed out that the role of technical tools is limited and needs to be connected with real support such as community patrols and liaison mechanisms. Due to the price increase, there have also been questions about the motivation for the price increase. The app's rise in popularity sparked discussions about taboos about death in China. Regarding the popularity of the application, both Southern Metropolis Daily and The Beijing News commented that it reflects the public issue of the risks of living alone and reflects the general anxiety of the living alone group about dying alone. Shangguan News further pointed out that although such technology products provide a certain "low-cost sense of security", their "cold notifications" may not only cause false alarms, but also highlight the embarrassing reality that "there is no one to fill in the emergency contact". It also emphasized that algorithms or applications cannot bring true happiness and called on society to reconstruct a support network full of humanistic care while relying on technology. The name of the application has also sparked controversy. Most netizens believe that the name "Are You Dead?" is unlucky and makes it awkward to share the application. They suggest changing it to a milder name such as "Are You Alive?". Hu Xijin also said that the name change could "give the elderly who use it more psychological comfort" and "believe that the application will become more popular after the name change". Some people also believe that this straightforward name just points out the real dilemma faced by people living alone and has a special meaning. BBC News commented that the name "Are You Dead" is playing a word game with Ele.me (Chinese: 饿了么; pinyin: Èleme) and the pronunciation is also similar. Legal professionals believe that its name is highly similar to Ele.me and may cause confusion. They also raised the possibility of trademark infringement and unfair competition. However, the developers said that the application is developed for young people and death is not a sensitive topic. They will "consider launching a new application that is more suitable for middle-aged and elderly people". They have not yet received any name change requests from relevant departments. On the evening of 13 January 2026, the Are You Dead? team announced that it would change its name to the English brand name Demumu in the upcoming new version. On 11 January, the development team also issued a statement through its official Weibo account, stating that it would study the renaming suggestion and plan to enrich the SMS reminder function, consider adding the message function and explore the direction of age-friendly products; it also stated that it would launch an 8 yuan paid plan to cover the costs of SMS, servers, etc., and welcomed investors to discuss cooperation. In terms of financing and valuation, it plans to sell 10% of the company's shares for 1 million yuan and proposed a valuation of 10 million yuan. On the evening of January 15, the application was removed from the app store in mainland China. == Functions == The application does not require users to enter phone numbers or other information to register. After filling in their name and setting an emergency contact, users can click the sign-in button every day. If they fail to sign in for two consecutive days, the system will send an email reminder to the emergency contact the next day. In addition, users can also bind a smart bracelet to monitor physiological signs, pre-designate a hearse driver and funeral music, and trigger the "one-click body collection" function when no pulse is detected. The application was initially available for free download, but a one yuan paid download option was introduced at the end of 2025. In January 2026, the application team issued a statement saying that an 8 yuan paid option would be launched based on the costs of SMS, servers, etc.
European Conference on Computer Vision
The European Conference on Computer Vision (ECCV) is a biennial research conference with the proceedings published by Springer Science+Business Media. Similar to ICCV in scope and quality, it is held those years which ICCV is not. It is considered to be one of the top conferences in computer vision, alongside CVPR and ICCV, with an 'A' rating from the Australian Ranking of ICT Conferences and an 'A1' rating from the Brazilian ministry of education. The acceptance rate for ECCV 2010 was 24.4% for posters and 3.3% for oral presentations. Like other top computer vision conferences, ECCV has tutorial talks, technical sessions, and poster sessions. The conference is usually spread over five to six days with the main technical program occupying three days in the middle, and tutorial and workshops, focused on specific topics, being held in the beginning and at the end. The ECCV presents the Koenderink Prize annually to recognize fundamental contributions in computer vision. == Location == The conference is usually held in autumn in Europe.