Dendral

Dendral was a project in artificial intelligence (AI) of the 1960s, and the computer software expert system that it produced. Its primary aim was to study hypothesis formation and discovery in science. For that, a specific task in science was chosen: help organic chemists in identifying unknown organic molecules, by analyzing their mass spectra and using knowledge of chemistry. It was done at Stanford University by Edward Feigenbaum, Bruce G. Buchanan, Joshua Lederberg, and Carl Djerassi, along with a team of highly creative research associates and students. It began in 1964 and spans approximately half the history of AI research. The software program Dendral is considered the first expert system because it automated the decision-making process and problem-solving behavior of organic chemists. The project consisted of research on two main programs Heuristic Dendral and Meta-Dendral, and several sub-programs. It was written in the Lisp programming language, which was considered the language of AI because of its flexibility. Many systems were derived from Dendral, including MYCIN, MOLGEN, PROSPECTOR, XCON, and STEAMER. There are many other programs today for solving the mass spectrometry inverse problem, see List of mass spectrometry software, but they are no longer described as 'artificial intelligence', just as structure searchers. The name Dendral is an acronym of the term "Dendritic Algorithm". == Heuristic Dendral == Heuristic Dendral is a program that uses mass spectra or other experimental data together with a knowledge base of chemistry to produce a set of possible chemical structures that may be responsible for producing the data. A mass spectrum of a compound is produced by a mass spectrometer, and is used to determine its molecular weight, the sum of the masses of its atomic constituents. For example, the compound water (H2O), has a molecular weight of 18 since hydrogen has a mass of 1.01 and oxygen 16.00, and its mass spectrum has a peak at 18 units. Heuristic Dendral would use this input mass and the knowledge of atomic mass numbers and valence rules, to determine the possible combinations of atomic constituents whose mass would add up to 18. As the weight increases and the molecules become more complex, the number of possible compounds increases drastically. Thus, a program that is able to reduce this number of candidate solutions through the process of hypothesis formation is essential. New graph-theoretic algorithms were invented by Lederberg, Harold Brown, and others that generate all graphs with a specified set of nodes and connection-types (chemical atoms and bonds) -- with or without cycles. Moreover, the team was able to prove mathematically that the generator is complete, in that it produces all graphs with the specified nodes and edges, and that it is non-redundant, in that the output contains no equivalent graphs (e.g., mirror images). The CONGEN program, as it became known, was developed largely by computational chemists Ray Carhart, Jim Nourse, and Dennis Smith. It was useful to chemists as a stand-alone program to generate chemical graphs showing a complete list of structures that satisfy the constraints specified by a user. == Meta-Dendral == Meta-Dendral is a machine learning system that receives the set of possible chemical structures and corresponding mass spectra as input, and proposes a set of rules of mass spectrometry that correlate structural features with processes that produce the mass spectrum. These rules would be fed back to Heuristic Dendral (in the planning and testing programs described below) to test their applicability. Thus, "Heuristic Dendral is a performance system and Meta-Dendral is a learning system". The program is based on two important features: the plan-generate-test paradigm and knowledge engineering. === Plan-generate-test paradigm === The plan-generate-test paradigm is the basic organization of the problem-solving method, and is a common paradigm used by both Heuristic Dendral and Meta-Dendral systems. The generator (later named CONGEN) generates potential solutions for a particular problem, which are then expressed as chemical graphs in Dendral. However, this is feasible only when the number of candidate solutions is minimal. When there are large numbers of possible solutions, Dendral has to find a way to put constraints that rules out large sets of candidate solutions. This is the primary aim of Dendral planner, which is a “hypothesis-formation” program that employs “task-specific knowledge to find constraints for the generator”. Last but not least, the tester analyzes each proposed candidate solution and discards those that fail to fulfill certain criteria. This mechanism of plan-generate-test paradigm is what holds Dendral together. === Knowledge Engineering === The primary aim of knowledge engineering is to attain a productive interaction between the available knowledge base and problem solving techniques. This is possible through development of a procedure in which large amounts of task-specific information is encoded into heuristic programs. Thus, the first essential component of knowledge engineering is a large “knowledge base.” Dendral has specific knowledge about the mass spectrometry technique, a large amount of information that forms the basis of chemistry and graph theory, and information that might be helpful in finding the solution of a particular chemical structure elucidation problem. This “knowledge base” is used both to search for possible chemical structures that match the input data, and to learn new “general rules” that help prune searches. The benefit Dendral provides the end user, even a non-expert, is a minimized set of possible solutions to check manually. == Heuristics == A heuristic is a rule of thumb, an algorithm that does not guarantee a solution, but reduces the number of possible solutions by discarding unlikely and irrelevant solutions. The use of heuristics to solve problems is called "heuristics programming", and was used in Dendral to allow it to replicate in machines the process through which human experts induce the solution to problems via rules of thumb and specific information. Heuristics programming was a major approach and a giant step forward in artificial intelligence, as it allowed scientists to finally automate certain traits of human intelligence. It became prominent among scientists in the late 1940s through George Polya’s book, How to Solve It: A New Aspect of Mathematical Method. As Herbert A. Simon said in The Sciences of the Artificial, "if you take a heuristic conclusion as certain, you may be fooled and disappointed; but if you neglect heuristic conclusions altogether you will make no progress at all." == History == During the mid 20th century, the question "can machines think?" became intriguing and popular among scientists, primarily to add humanistic characteristics to machine behavior. John McCarthy, who was one of the prime researchers of this field, termed this concept of machine intelligence as "artificial intelligence" (AI) during the Dartmouth summer in 1956. AI is usually defined as the capacity of a machine to perform operations that are analogous to human cognitive capabilities. Much research to create AI was done during the 20th century. Also around the mid 20th century, science, especially biology, faced a fast-increasing need to develop a "man-computer symbiosis", to aid scientists in solving problems. For example, the structural analysis of myoglobin, hemoglobin, and other proteins relentlessly needed instrumentation development due to its complexity. In the early 1960s, Joshua Lederberg started working with computers and quickly became tremendously interested in creating interactive computers to help him in his exobiology research. Specifically, he was interested in designing computing systems to help him study alien organic compounds. Lederberg had been heading a team designing instruments for the Mars Viking lander to search for precursor molecules of life in samples of the Mars surface, using a mass spectrometer coupled with a minicomputer. As he was not an expert in either chemistry or computer programming, he collaborated with Stanford chemist Carl Djerassi to help him with chemistry, and Edward Feigenbaum with programming, to automate the process of determining chemical structures from raw mass spectrometry data. Feigenbaum was an expert in programming languages and heuristics, and helped Lederberg design a system that replicated the way Djerassi solved structure elucidation problems. They devised a system called Dendritic Algorithm (Dendral) that was able to generate possible chemical structures corresponding to the mass spectrometry data as an output. Dendral then was still very inaccurate in assessing spectra of ketones, alcohols, and isomers of chemical compounds. Thus, Djerassi "taught" general rules to Dendral that could help eliminate most of the "chemically implausible" structures, and p

Transduction (machine learning)

In logic, statistical inference, and supervised learning, transduction or transductive inference is reasoning from observed, specific (training) cases to specific (test) cases. In contrast, induction is reasoning from observed training cases to general rules, which are then applied to the test cases. The distinction is most interesting in cases where the predictions of the transductive model are not achievable by any inductive model. Note that this is caused by transductive inference on different test sets producing mutually inconsistent predictions. Transduction was introduced in a computer science context by Vladimir Vapnik in the 1990s, motivated by his view that transduction is preferable to induction since, according to him, induction requires solving a more general problem (inferring a function) before solving a more specific problem (computing outputs for new cases): "When solving a problem of interest, do not solve a more general problem as an intermediate step. Try to get the answer that you really need but not a more general one.". An example of learning which is not inductive would be in the case of binary classification, where the inputs tend to cluster in two groups. A large set of test inputs may help in finding the clusters, thus providing useful information about the classification labels. The same predictions would not be obtainable from a model which induces a function based only on the training cases. Some people may call this an example of the closely related semi-supervised learning, since Vapnik's motivation is quite different. The most well-known example of a case-bases learning algorithm is the k-nearest neighbor algorithm, which is related to transductive learning algorithms. Another example of an algorithm in this category is the Transductive Support Vector Machine (TSVM). A third possible motivation of transduction arises through the need to approximate. If exact inference is computationally prohibitive, one may at least try to make sure that the approximations are good at the test inputs. In this case, the test inputs could come from an arbitrary distribution (not necessarily related to the distribution of the training inputs), which wouldn't be allowed in semi-supervised learning. An example of an algorithm falling in this category is the Bayesian Committee Machine (BCM). == Historical context == The mode of inference from particulars to particulars, which Vapnik came to call transduction, was already distinguished from the mode of inference from particulars to generalizations in part III of the Cambridge philosopher and logician W.E. Johnson's 1924 textbook, Logic. In Johnson's work, the former mode was called 'eduction' and the latter was called 'induction'. Bruno de Finetti developed a purely subjective form of Bayesianism in which claims about objective chances could be translated into empirically respectable claims about subjective credences with respect to observables through exchangeability properties. An early statement of this view can be found in his 1937 La Prévision: ses Lois Logiques, ses Sources Subjectives and a mature statement in his 1970 Theory of Probability. Within de Finetti's subjective Bayesian framework, all inductive inference is ultimately inference from particulars to particulars. == Example problem == The following example problem contrasts some of the unique properties of transduction against induction. A collection of points is given, such that some of the points are labeled (A, B, or C), but most of the points are unlabeled (?). The goal is to predict appropriate labels for all of the unlabeled points. The inductive approach to solving this problem is to use the labeled points to train a supervised learning algorithm, and then have it predict labels for all of the unlabeled points. With this problem, however, the supervised learning algorithm will only have five labeled points to use as a basis for building a predictive model. It will certainly struggle to build a model that captures the structure of this data. For example, if a nearest-neighbor algorithm is used, then the points near the middle will be labeled "A" or "C", even though it is apparent that they belong to the same cluster as the point labeled "B", compared to semi-supervised learning. Transduction has the advantage of being able to consider all of the points, not just the labeled points, while performing the labeling task. In this case, transductive algorithms would label the unlabeled points according to the clusters to which they naturally belong. The points in the middle, therefore, would most likely be labeled "B", because they are packed very close to that cluster. An advantage of transduction is that it may be able to make better predictions with fewer labeled points, because it uses the natural breaks found in the unlabeled points. One disadvantage of transduction is that it builds no predictive model. If a previously unknown point is added to the set, the entire transductive algorithm would need to be repeated with all of the points in order to predict a label. This can be computationally expensive if the data is made available incrementally in a stream. Further, this might cause the predictions of some of the old points to change (which may be good or bad, depending on the application). A supervised learning algorithm, on the other hand, can label new points instantly, with very little computational cost. == Transduction algorithms == Transduction algorithms can be broadly divided into two categories: those that seek to assign discrete labels to unlabeled points, and those that seek to regress continuous labels for unlabeled points. Algorithms that seek to predict discrete labels tend to be derived by adding partial supervision to a clustering algorithm. Two classes of algorithms can be used: flat clustering and hierarchical clustering. The latter can be further subdivided into two categories: those that cluster by partitioning, and those that cluster by agglomerating. Algorithms that seek to predict continuous labels tend to be derived by adding partial supervision to a manifold learning algorithm. === Partitioning transduction === Partitioning transduction can be thought of as top-down transduction. It is a semi-supervised extension of partition-based clustering. It is typically performed as follows: Consider the set of all points to be one large partition. While any partition P contains two points with conflicting labels: Partition P into smaller partitions. For each partition P: Assign the same label to all of the points in P. Of course, any reasonable partitioning technique could be used with this algorithm. Max flow min cut partitioning schemes are very popular for this purpose. === Agglomerative transduction === Agglomerative transduction can be thought of as bottom-up transduction. It is a semi-supervised extension of agglomerative clustering. It is typically performed as follows: Compute the pair-wise distances, D, between all the points. Sort D in ascending order. Consider each point to be a cluster of size 1. For each pair of points {a,b} in D: If (a is unlabeled) or (b is unlabeled) or (a and b have the same label) Merge the two clusters that contain a and b. Label all points in the merged cluster with the same label. === Continuous Label Transduction === These methods seek to regress continuous labels, often via manifold learning techniques. The idea is to learn a low-dimensional representation of the data and infer values smoothly across the manifold. == Applications and related concepts == Transduction is closely related to: Semi-supervised learning – uses both labeled and unlabeled data but typically induces a model. Case-based reasoning – such as the k-nearest neighbor (k-NN) algorithm, often considered a transductive method. Transductive Support Vector Machines (TSVM) – extend standard SVMs to incorporate unlabeled test data during training. Bayesian Committee Machine (BCM) – an approximation method that makes transductive predictions when exact inference is too costly.

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Vero (app)

Vero (stylized as VERO) is a social media platform and mobile app company. Vero markets itself as a social network free from advertisements, data mining and algorithms. == History == The app was founded by French-Lebanese billionaire Ayman Hariri who is the son of former Lebanese prime minister Rafic Hariri. The name is taken from the Italian word for true. The app launched officially in 2015 as an alternative to Facebook and their popular photo-blogging app Instagram. Within weeks of its release the app surged in popularity although users expressed mixed reports with some feeling confused about how the app worked. Cosplayers were early to adopt the app as their photo-sharing platform of choice, favouring the app's pinch and zoom magnification feature over Instagram's zoom feature. Other creative communities soon followed, and the app became popular with niche groups of makeup artists, tattoo artists, and skateboarders. In March 2018, Vero's popularity surged, partly helped by an exodus from Facebook and Instagram following the Cambridge Analytica data scandal. In the wake of the scandal, Vero devised an advertising campaign aimed at defected Facebook and Instagram users, hoping the app's policies and privacy settings would assuage concerns over sharing personal information on the internet. Within the space of one week, the app went from being a small service, akin to Ello or Peach, to being the most downloaded app in eighteen countries. In December 2020, Vero released its most significant update to date, Vero 2.0 which introduced new features including voice and video calls, game and app posts and bookmarks, and refinements to the UI. In October 2021, Vero introduced their Desktop app (beta) with multiple post options and a re-sizable multi-column feed. == Concept and funding == Vero's content feed resembles Instagram's although users can share a wider variety of content and the app has a chronological content feed whereas Facebook and Instagram's feeds are algorithm based. Vero's business plan is also distinct from similar social media apps. Whereas its competitors such as Facebook or Instagram make money from in-app advertising revenue and the sale of user data, Vero's business plan was to invite the first one million users to use the app for free then charge any subsequent users a subscription fee. The app was entirely funded by its founder and generated additional revenues by charging affiliate fees when someone buys a product they find on Vero. == Awards == Vero was recognized at the 2021 Webbys, being named as an Honoree in the Best Visual Design - Aesthetic Category. == Controversies == === Privacy === Vero has faced some criticism over the wording of their manifesto, in particular, the statement "Vero only collects the data we believe is necessary to provide users with a great experience and to ensure the security of their accounts." Because this policy does not explicitly state that the app will not sell data on to third parties some users fear that the need to monetise the app through data might prove too tempting. Users have also complained about not being able to delete their accounts. While this was never the case, the option was hidden deep in the app's settings. === Russian involvement === Although Vero remains transparent about the app's Russian development team, they have been caught up in concerns about Russian interference on social media platforms. The app's founder Ayman Hariri was quick to dismiss the remarks as xenophobic and defend the nationality of his employees, stating in an interview with Time Magazine; "At the end of the day, where people are from is really not how anybody should judge anyone". === Criticism of the app's founder === Until 2013, Vero's founder Ayman Harari was deputy CEO and chairman of Saudi Oger, the Saudi Arabian construction company which collapsed in 2017, mired by controversies over the welfare and treatment of their employees. However, Hariri is quick to point out that he divested from the firm in 2014 and the worker's rights violations occurred after he had left the company.

Vera Demberg

Vera Demberg (born 1981) is a German computational linguist and professor of computer science and computational linguistics at Saarland University. Her research interests include cognitive models of human language comprehension, natural language generation, experimental psycholinguistics, multimodal language processing in a dual-task setting, and experimental and computational discourse research and pragmatics. == Career and research == Vera Demberg studied computational linguistics at the Institute for Machine Language Processing at the University of Stuttgart from 2001 to 2006. She then completed a Master's degree in Artificial Intelligence at the University of Edinburgh from 2004 to 2005. She received her Ph.D. from the Department of Computer Science there from 2006 to 2010. Her dissertation paper, titled “Broad-Coverage Model of Prediction in Human Sentence Processing”, was awarded the Cognitive Science Society's “Glushko Dissertation Prize in Cognitive Science” in 2011. In her work, she designed a model of human sentence processing that can be used to predict difficulties in processing at the syntactic level. From 2010 to 2016, Vera Demberg led an independent research group on cognitive models of human language processing and their application to speech dialog systems in the Cluster of Excellence “Multimodal Computing and Interaction” at the University of Saarland. In 2016, she was appointed there to a professorship in computer science and computational linguistics. Demberg's professorship is in the Department of Computer Science (Faculty of Mathematics and Computer Science). She is also a co-opted professor in the Department of Linguistics and Language Technology (Faculty of Philosophy). Since 2020, she has led the ERC Starting Grant “Individualized Interaction in Discourse”. The project conducts research on how to make linguistic interaction with computer systems more natural. She has authored and co-authored numerous papers on the study of computational linguistics and natural language processing. According to Google Scholar, Vera Demberg has an H-index of 30. == Publications == Vera Demberg has authored more than 200 papers; please refer to her scholar page at https://scholar.google.com/citations?user=l2CFSAMAAAAJ == Awards == 2011: Cognitive Science Society Glushko Dissertation Prize in Cognitive Science 2020: ERC Starting Grant “Individualized Interaction in Discourse” 2024: Member of the Academy of Sciences and Literature