AI Analytics Healthcare

AI Analytics Healthcare — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

PhotoWorks (ray tracing software)

PhotoWorks is a raytrace rendering program created by Dassault Systèmes SolidWorks Corporation, formerly supplied as a photorealistic rendering add-in for SolidWorks. The program is based on the Mental Ray rendering engine. It has a library of scenes and materials that can be used with user-created SolidWorks files to create still frame images within the SolidWorks GUI. Since the 2011 release of SolidWorks, PhotoWorks has been replaced by the PhotoView 360 rendering utility. A 2010 review comparing PhotoWorks with three other rendering programs for SolidWorks (including PhotoView 360) gave the program high marks for render speed and built-in materials, but low marks for realism and user interface. Appearance File Type: .p2m
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ACLU Mobile Justice

ACLU Mobile Justice was a video live streaming application developed for smartphones by various state chapters of the American Civil Liberties Union. It was intended to allow instant, secure video recording and transmission of interactions with, and perceived abuses by, law enforcement officers. Since its release by the ACLU of California for California residents, other versions of the app have been released for 16 other states and the District of Columbia by their ACLU chapters. It was discontinued in February 2025.
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Iterative reconstruction

Iterative reconstruction refers to iterative algorithms used to reconstruct 2D and 3D images in certain imaging techniques. For example, in computed tomography an image must be reconstructed from projections of an object. Here, iterative reconstruction techniques are usually a better, but computationally more expensive alternative to the common filtered back projection (FBP) method, which directly calculates the image in a single reconstruction step. In recent research works, scientists have shown that extremely fast computations and massive parallelism is possible for iterative reconstruction, which makes iterative reconstruction practical for commercialization. == Basic concepts == The reconstruction of an image from the acquired data is an inverse problem. Often, it is not possible to exactly solve the inverse problem directly. In this case, a direct algorithm has to approximate the solution, which might cause visible reconstruction artifacts in the image. Iterative algorithms approach the correct solution using multiple iteration steps, which allows to obtain a better reconstruction at the cost of a higher computation time. There are a large variety of algorithms, but each starts with an assumed image, computes projections from the image, compares the original projection data and updates the image based upon the difference between the calculated and the actual projections. === Algebraic reconstruction === The Algebraic Reconstruction Technique (ART) was the first iterative reconstruction technique used for computed tomography by Hounsfield. === Iterative Sparse Asymptotic Minimum Variance === The iterative sparse asymptotic minimum variance algorithm is an iterative, parameter-free superresolution tomographic reconstruction method inspired by compressed sensing, with applications in synthetic-aperture radar, computed tomography scan, and magnetic resonance imaging (MRI). === Statistical reconstruction === There are typically five components to statistical iterative image reconstruction algorithms, e.g. An object model that expresses the unknown continuous-space function f ( r ) {\displaystyle f(r)} that is to be reconstructed in terms of a finite series with unknown coefficients that must be estimated from the data. A system model that relates the unknown object to the "ideal" measurements that would be recorded in the absence of measurement noise. Often this is a linear model of the form A x + ϵ {\displaystyle \mathbf {A} x+\epsilon } , where ϵ {\displaystyle \epsilon } represents the noise. A statistical model that describes how the noisy measurements vary around their ideal values. Often Gaussian noise or Poisson statistics are assumed. Because Poisson statistics are closer to reality, it is more widely used. A cost function that is to be minimized to estimate the image coefficient vector. Often this cost function includes some form of regularization. Sometimes the regularization is based on Markov random fields. An algorithm, usually iterative, for minimizing the cost function, including some initial estimate of the image and some stopping criterion for terminating the iterations. === Learned Iterative Reconstruction === In learned iterative reconstruction, the updating algorithm is learned from training data using techniques from machine learning such as convolutional neural networks, while still incorporating the image formation model. This typically gives faster and higher quality reconstructions and has been applied to CT and MRI reconstruction. == Advantages == The advantages of the iterative approach include improved insensitivity to noise and capability of reconstructing an optimal image in the case of incomplete data. The method has been applied in emission tomography modalities like SPECT and PET, where there is significant attenuation along ray paths and noise statistics are relatively poor. Statistical, likelihood-based approaches: Statistical, likelihood-based iterative expectation-maximization algorithms are now the preferred method of reconstruction. Such algorithms compute estimates of the likely distribution of annihilation events that led to the measured data, based on statistical principle, often providing better noise profiles and resistance to the streak artifacts common with FBP. Since the density of radioactive tracer is a function in a function space, therefore of extremely high-dimensions, methods which regularize the maximum-likelihood solution turning it towards penalized or maximum a-posteriori methods can have significant advantages for low counts. Examples such as Ulf Grenander's Sieve estimator or Bayes penalty methods, or via I.J. Good's roughness method may yield superior performance to expectation-maximization-based methods which involve a Poisson likelihood function only. As another example, it is considered superior when one does not have a large set of projections available, when the projections are not distributed uniformly in angle, or when the projections are sparse or missing at certain orientations. These scenarios may occur in intraoperative CT, in cardiac CT, or when metal artifacts require the exclusion of some portions of the projection data. In Magnetic Resonance Imaging it can be used to reconstruct images from data acquired with multiple receive coils and with sampling patterns different from the conventional Cartesian grid and allows the use of improved regularization techniques (e.g. total variation) or an extended modeling of physical processes to improve the reconstruction. For example, with iterative algorithms it is possible to reconstruct images from data acquired in a very short time as required for real-time MRI (rt-MRI). In Cryo Electron Tomography, where the limited number of projections are acquired due to the hardware limitations and to avoid the biological specimen damage, it can be used along with compressive sensing techniques or regularization functions (e.g. Huber function) to improve the reconstruction for better interpretation. Here is an example that illustrates the benefits of iterative image reconstruction for cardiac MRI.
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Lawbot

Lawbots are a broad class of customer-facing legal AI applications that are used to automate specific legal tasks, such as document automation and legal research. The terms robot lawyer and lawyer bot are used as synonyms to lawbot. A robot lawyer or a robo-lawyer refers to a legal AI application that can perform tasks that are typically done by paralegals or young associates at law firms. However, there is some debate on the correctness of the term. Some commentators say that legal AI is technically speaking neither a lawyer nor a robot and should not be referred to as such. Other commentators believe that the term can be misleading and note that the robot lawyer of the future will not be one all-encompassing application but a collection of specialized bots for various tasks. Lawbots use various artificial intelligence techniques or other intelligent systems to limit humans' direct ongoing involvement in certain steps of a legal matter. The user interfaces on lawbots vary from smart searches and step-by-step forms to chatbots. Consumer and enterprise-facing lawbot solutions often do not require direct supervision from a legal professional. Depending on the task, some client-facing solutions used at law firms operate under an attorney supervision. == Levels of autonomy == The following levels of autonomy (LoA) are suggested for automated AI legal reasoning: Level 0 (LoA0): No automation for AI legal reasoning Level 1 (LoA1): Simple assistance automation Level 2 (LoA2): Advanced assistance automation Level 3 (LoA3): Semi-autonomous automation Level 4 (LoA4): Domain automation Level 5 (LoA5): Fully-autonomous automation Level 6 (LoA6): Superhuman automation == Examples == Some legal AI solutions are developed and marketed directly to the customers or consumers, whereas other applications are tools for the attorneys at law firms. There are already hundreds of legal AI solutions that operate in multitude of ways varying in sophistication and dependence on scripted algorithms. One notable legal technology chatbot application is DoNotPay. It had started off as an app for contesting parking tickets, but has since expanded to include features that help users with many different types of legal issues, ranging from consumer protection to immigration rights and other social issues. == Impact on the legal industry == In the 2016 report, Deloitte estimated that more than 110,000 law jobs in just the United Kingdom alone could disappear within the next twenty years due to automation. This change could result in the creation of more highly skilled jobs and in the reduction of paralegal and temporary positions. Deloitte's report asserts that "there is significant potential for high-skilled roles that involve repetitive processes to be automated by smart and self-learning algorithms". According to Lawyers to Engage, between 22% of a lawyer’s work and 35% of a legal assistant’s work can be automated in the US. Top law schools like Harvard have already begun to integrate Artificial Intelligence into the curriculum. Legal tech start-up companies have begun developing applications that assist law firms with completing low-risk legal processes. These applications can enable lawyers to focus on more work that requires their specific expertise. The automation of processes like contract reviewing, enforcement of negotiations (smart contracts) and client intake (expert systems) allows law firms to streamline their procedures and improve efficiency. In addition, automation benefits small-to-medium law firms that do not have the resources to utilize junior talent on such routine tasks. The increase of law firms utilizing automated applications could result into legal tech becoming a necessity in the industry. Digital Reason CEO, Tim Estes, stated that those who refuse the opportunity to integrate AI in their workflow are “most at risk.” In 2018, Forbes reported a 713% increase in investments in legal tech. This rapid growth is reflective of law firms beginning to “cede business to… new model legal providers… that meld technological, business and legal expertise.” == Access to law and justice == It has been widely estimated for at least the last generation that all the programs and resources devoted to ensuring access to justice address only 20% of the civil legal needs of low-income people in the United States. Drawing on this experience, in late 2011, the U.S. government-funded Legal Services Corporation decided to convene a summit of leaders to explore how best to use technology in the access-to-justice community. The group adopted a mission for The Summit on the Use of Technology to Expand Access to Justice (Summit) consistent with the magnitude of the challenge: "to explore the potential of technology to move the United States toward providing some form of effective assistance to 100% of persons otherwise unable to afford an attorney for dealing with essential civil legal needs". In April 2017, joined by Microsoft and Pro Bono Net, the Legal Services Corporation (LSC) announced a pilot program to develop online, statewide legal portals to direct individuals with civil legal needs to the most appropriate forms of assistance. == Technological limitations == Current research in subjects such as computational privacy, explainable machine learning, Bayesian deep learning, knowledge-intensive machine learning, and transfer learning reveals that we do not yet have the technology to enable Level 4 to 6 AI lawbots. In 2023, OpenLaw began developing a model called Law Bot, which interacts in a conversational way as an attorney. The dialogue format makes it possible for Law Bot to answer follow-up questions, challenge incorrect premises, and reject inappropriate requests. Currently, they try to ensure it is in full compliance with all laws and regulations while conducting further beta testing before releasing it to the general public.
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Online OS

The Online Operating System was a fully multi-lingual and free to use web desktop written in JavaScript using Ajax. It was a Windows-based desktop environment with open-source applications and system utilities developed upon the reBOX web application framework by iCUBE Network Solutions, an Austrian company located in Vienna. == About the project == OOS.cc, which is short for Online Operating System, was a web application platform that mimicked the look and feel of classic desktop operating systems such as Microsoft Windows, Mac OS X or KDE. It consisted of various open source applications built upon the so-called reBOX web application framework. As applications could be executed in an integrated and parallel way, the OOS could have been considered a web desktop or webtop. It provided basic services such as a GUI, a virtual file system, access control management and possibilities to develop and deploy applications online. As the Online Operating System was executed within a web browser, it was no real operating system but rather a portal to various web applications, offering a high usability and flexibility. The project was partly funded by grants from the Internetprivatstiftung Austria (IPA). As at 01.08.2008 almost 20.000 users have joined the oos.cc community, using the offered featured and applications. == History == The development of the web desktop was started by iCUBE Network Solutions in 2005, followed by the first beta releases in 2006. Hence, together with YouOS and eyeOS, it can be considered to be one of the first publicly available systems of its kind. The first full version including core-level multi-language support, the file system and a basic set of applications was released to the public in March 2007 on the occasion of a national exhibition (ITnT Austria Archived 2007-06-30 at the Wayback Machine) and has left beta state half a year later in October 2007. The first release considered stable (1.0.0) was published in July 2007. The project itself and the contained applications have received several national innovation awards (see,) and have gained attention mainly due to the comprehensive approach taken (see,). OOS.cc started as a national project. The full platform including all offered applications are currently available in three languages (German, English as well as Spanish) and is receiving increasing coverage around the world (for examples see, or). The current version is 1.3.01 from 01.08.2008. == Technical overview == The project is fully written in JavaScript, exclusively using DHTML techniques to run in any web browser without any additional software installation needed. The system implements a modern kind of web application model, excessively using Ajax for communicating between client components and the Java server backend in an exclusively asynchronous manner. Aim is to offer users the unique interaction behavior following the desktop metaphor, which is the main idea of any web desktop. Also typical for this sort of web application is the broadly use of Javascript-on-demand techniques, cutting the complete project source into pieces and loading them instantly when needed. Based on this technical basis, reBOX was the framework library all applications in oos.cc were built of. It is a fully flexible and extensible API, including a GUI widget set, communication mechanisms and server services offering general and framework specific services. The Online Operating System itself consisted of a basic framework, which was able to launch any JavaScript application using the reBOX library. The user interface was based on the behavior of the Windows desktop with a start menu, a task bar and a desktop background. All applications were running in this environment. At server side, there were Java based web services that ran to serve the client processes and to provide data from the relational database in the backend. oos.cc also provided an integrated development environment called Developer Suite, which allowed the community to build own applications for the desktop environment based on reBOX (see development section below). == License == All applications available in oos.cc were open source under the European Union Public Licence (EUPL). The reBOX development toolkit is free to use developing any applications for the webtop. == Features == As mentioned above, all applications published on oos.cc are open source based on the EUPL, and can be "installed" or "deinstalled" to what-ever preferences the user has. Besides global services like the multi-language support or the global theme support, as well as some minor tools and games, oos.cc offered four major services that could be used completely free of charge. Integrated and fully flexible file storage (1 GB per user) HTTP as well as FTP file transfer from and to local file system User-based file-shares within the oos-community WebDAV access Document Management (including Version Control and File Locking mechanisms) Image publishing, organization and post-processing A free sub domain (user.oos.cc) for web- or image publishing, directly integrated in the desktop Groupware applications, including free mail, fetchmail and contact management An integrated development environment where oos-applications can be created directly from within the system (see development section below) Next releases were planned to focus on an extensive security and privacy suite, dealing with challenges like anonymous communication (browsing as well as temporary mail-addresses) as well as offering encrypted password and file storage and connectivity services. Since its initial stable release, OOS.cc could have been accessed using https to ensure secure communication. == Limitations and drawbacks == Limited number of applications: no commercial applications can be hosted. Only reviewed applications are being published No processing of popular office formats (.doc, .odt, etc.) Limited language support: Only English, German and Spanish Dependence on foreign infrastructure: No possibility to extend storage, no additional/guaranteed bandwidth, etc. == Development == One of the key focuses of the team was right from the beginning to offer a very flexible and comprehensive API, that can be used to develop not only custom applications within oos.cc, but also stand-alone web-applications or to integrate single components in existing web-sites. By decoupling the development from web-related "problems" using the reBOX API web-applications can be development in a similar fashion to any Java program: Elements can be positioned and can interact like in high-level object oriented programming languages, without taking care of divs, browser specific behavior or communication handling. The framework also offers multi-language and theme support for existing as well as newly created applications, allowing changing almost every aspect of the look and feel of the used components according to the preferences of its users. For taking advantage of this approach, one of the applications offered in the OOS was an integrated Development Suite, allowing directly writing and executing code and hence creating new programs within the boundaries of the web computer. All applications on oos.cc were released as open source, thus all existing programs were offered to be imported, reviewed or changed and then locally deployed. Following this idea, every user was free to submit changed or newly created applications to be included in the globally offered application set. The last release offered features like auto-completion and an outline-window.
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Affinity (software)

Affinity is a graphics editor developed by Serif, a subsidiary of Canva. It is simultaneously a vector graphics editor, a raster graphics editor and a desktop publishing application. It was first released in 2025 as a successor to Serif's Affinity Designer, Affinity Photo and Affinity Publisher, uniting the three editors into one application. While the previous versions competed individually against Adobe's Illustrator, Photoshop, and InDesign, Affinity 3.0 integrates their functionality into a single application. It uses a freemium model monetized by AI features exclusive to Canva Pro subscribers. == Functionality == Affinity is divided into a number of workspaces ("studios"), which are equivalent to the previous suite of Affinity applications: "vector" for vector graphics (Designer), "pixel" for raster editing (Photo), and "layout" for desktop publishing (Publisher). Additionally, it introduces the ability to create custom workspaces. The application supports real-time previews and non-destructive editing, which are based on GPU acceleration. Supported file formats include Adobe Photoshop, InDesign and Illustrator files, PDF, SVG, and TIFF, as well as a custom .af file format. === Vector editing === === Raster editing === Affinity includes photo editing tools including adjustments, masks, blend modes, batch processing, and retouching facilities. Additionally, the application can develop RAW files, similar to Adobe Lightroom. === Desktop publishing === Publishing features include master pages, text styles, and advanced typography. === AI features === The application supports Canva's existing AI features, such as background removal and generative fill. This requires a Canva subscription. == Development == === Background and acquisition (2014–2024) === Serif launched the original Affinity suite starting with Affinity Designer in 2014, followed by Photo (2015) and Publisher (2019). The software gained popularity for its one-time purchase model, contrasting with Adobe's subscription-based Creative Cloud. In November 2022, Serif released Version 2 of the suite, introducing a "Universal License" that covered all three apps across all platforms. In March 2024, Canva acquired Serif for approximately A$580 million (£300 million). Following user backlash regarding a potential shift to subscriptions, Canva and Serif issued a joint "Pledge" committing to four key principles: fair pricing, no mandatory subscriptions, perpetual licenses for existing products, and continued development of Affinity as a standalone suite. === Unified release (2025) === In September 2025, Serif pulled all existing versions of Affinity Designer, Affinity Photo and Affinity Publisher from sale ahead an upcoming announcement on 30 October; also ahead of the announcement, the iPadOS versions of the Affinity suite became free on App Store. During a "Creative Freedom" keynote on 30 October 2025, Canva released a new version now simply branded as "Affinity" (also known as "Affinity by Canva"), and referred to internally as version 3.0. Version 3 drops the separate applications and integrates their functionality into a singular application, and adds the ability to export directly to the Canva platform. It also adds a Canva AI studio, including background removal, "Expand & Edit", and generative fill. As of version 3, Affinity has switched to a freemium model; it is now available at no charge to users, although access to Canva AI features are locked behind the existing Canva Pro subscription service. Serif stated that the perpetually-licensed version 2 will remain available to existing owners, although it will no longer be actively maintained. The new version is currently available for macOS and Windows only, with an iPadOS version to be released soon. == Reception == The change in business model by Canva in 2025 was met with mixed reception, including concerns about its incorporation of AI features. Some users were concerned that their projects would be used for machine learning purposes, or that future versions would suffer from a lack of maintenance or become adware. Additionally, some felt it turned Affinity into fundamentally subscription-based software, given the prevalence of these features in professional contexts. Affinity publicly stated on social media that it would remain "free forever", users' projects would not be used to train AI models, and that "Canva has built a sustainable business model that allows this kind of generosity. And when more professionals use Affinity, Canva can sell more seats into businesses."
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Plotly

Plotly is a technical computing company headquartered in Montreal, Quebec, that develops online data analytics and visualization tools. Plotly provides online graphing, analytics, and statistics tools for individuals and collaboration, as well as scientific graphing libraries for Python, R, MATLAB, Perl, Julia, Arduino, JavaScript and REST. == History == Plotly was founded by Alex Johnson, Jack Parmer, Chris Parmer, and Matthew Sundquist. The founders' backgrounds are in science, energy, and data analysis and visualization. Early employees include Christophe Viau, a Canadian software engineer and Ben Postlethwaite, a Canadian geophysicist. Plotly was named one of the Top 20 Hottest Innovative Companies in Canada by the Canadian Innovation Exchange. Plotly was featured in "startup row" at PyCon 2013, and sponsored the SciPy 2018 conference. Plotly raised $5.5 million during its Series A funding, led by MHS Capital, Siemens Venture Capital, Rho Ventures, Real Ventures, and Silicon Valley Bank. The Boston Globe and Washington Post newsrooms have produced data journalism using Plotly. In 2020, Plotly was named a Best Place to Work by the Canadian SME National Business Awards, and nominated as Business of the Year. == Products == Plotly offers open-source and enterprise products. Dash is an open-source Python, R, and Julia framework for building web-based analytic applications. Many specialized open-source Dash libraries exist that are tailored for building domain-specific Dash components and applications. Some examples are Dash DAQ, for building data acquisition GUIs to use with scientific instruments, and Dash Bio, which enables users to build custom chart types, sequence analysis tools, and 3D rendering tools for bioinformatics applications. Dash Enterprise is Plotly's paid product for building, testing, deploying, managing and scaling Dash applications organization-wide. Chart Studio Cloud is a free, online tool for creating interactive graphs. It has a point-and-click graphical user interface for importing and analyzing data into a grid and using stats tools. Graphs can be embedded or downloaded. Chart Studio Enterprise is a paid product that allows teams to create, style, and share interactive graphs on a single platform. It offers expanded authentication and file export options, and does not limit sharing and viewing. Data visualization libraries Plotly.js is an open-source JavaScript library for creating graphs and powers Plotly.py for Python, as well as Plotly.R for R, MATLAB, Node.js, Julia, and Arduino and a REST API. Plotly can also be used to style interactive graphs with Jupyter notebook. Figure converters which convert matplotlib, ggplot2, and IGOR Pro graphs into interactive, online graphs. == Data visualization libraries == Plotly provides a collection of supported chart types across several programming languages: == Dash == Dash is a Python framework built on top of React, a JavaScript library. Dash also works for R, and most recently supports Julia. While still described as a Python framework, Python isn't used for the other languages: "... describing Dash as a Python framework misses a key feature of its design: the Python side (the back end/server) of Dash was built to be lightweight and stateless [allowing] multiple back-end languages to coexist on an equal footing". It is possible to integrate D3.js charts as Dash components. Dash provides the default CSS (plus HTML and JavaScript), but for custom styling Dash applications, CSS can be added, or Dash Enterprise used. === Dash Enterprise === Dash Enterprise is Plotly's paid product for building, testing, deploying, managing and scaling Dash applications organization-wide. The product integrates with enterprise IT systems to enable organizations to build, deploy and scale low-code Dash applications. With open-source Dash, analytic applications can be run from a local machine, but cannot be easily accessed by others in the organization. ==== Enterprise IT integration ==== Dash Enterprise installs on cloud environments and on-premises. Amazon Web Services, Google Cloud Platform, and Microsoft Azure are supported, as are multiple Linux on-premises servers. Authentication integrations include LDAP, AD, PKI, Okta, SAML, OAuth2, SSO, and email authentication, and Dash application access is managed through a GUI rather than code. Dash Enterprise connects to major big data backends, including Salesforce, PostgreSQL, Databricks via PySpark, Snowflake, Dask, Datashader, and Vaex. In 2020, Plotly partnered with NVIDIA to integrate Dash with RAPIDS, and NVIDIA participated in Plotly's Series C funding round. ==== Low-code capabilities ==== Dash Enterprise enables low-code development of Dash applications, which is not possible with open-source Dash. Enterprise users can write applications in multiple development environments, including Jupyter Notebook. Dash Enterprise ships with several “development engines” for drag-and-drop application editing, application design, and automated reporting, as well as dozens of artificial intelligence and machine learning application templates. ==== Deployment and scaling ==== Dash application code is deployed to Dash Enterprise using the git-push command. Dash application deployments are containerized to avoid dependency conflicts, and can be embedded in existing web platforms without iframes. Deployed applications can be managed and accessed in a single portal called App Manager, where administrators can control user authentication and view usage analytics. Dash Enterprise scales horizontally with Kubernetes. Jobs queuing, GPU acceleration, and CPU parallelization support high performance computing requirements. Plotly also offers professional services for application development and workshop training.
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Pharmacy automation

Pharmacy automation involves the mechanical processes of handling and distributing medications. Any pharmacy task may be involved, including counting small objects (e.g., tablets, capsules); measuring and mixing powders and liquids for compounding; tracking and updating customer information in databases (e.g., personally identifiable information (PII), medical history, drug interaction risk detection); and inventory management. This article focuses on the changes that have taken place in the local, or community pharmacy since the 1960s. == History == Dispensing medications in a community pharmacy before the 1970s was a time-consuming operation. The pharmacist dispensed prescriptions in tablet or capsule form with a simple tray and spatula. Many new medications were developed by pharmaceutical manufacturers at an ever-increasing pace, and medications prices were rising steeply. A typical community pharmacist was working longer hours and often forced to hire staff to handle increased workloads which resulted in less time to focus on safety issues. These additional factors led to use of a machine to count medications. The original electronic portable digital tablet counting technology was invented in Manchester, England between 1967 and 1970 by the brothers John and Frank Kirby. I had the original idea of how the machine would work and it was my patent, but it was a joint effort getting it to work in a saleable form. It was 3 years of very hard work. I had originally studied heavy electrical engineering before changing over to Medical School and qualifying as a Medical Doctor in 1968. In fact I was Senior House (Casualty) Officer (A&E or ER) in 1970 at North Manchester General Hospital when I filed the patent. I must have been the only hospital doctor in Britain with an oscilloscope, a soldering iron and a drawing board in his room in the Doctors' Residence. The housekeepers were bemused by all the wires. Frank originally trained as a Banker but quit to take a job with a local electronics firm during the development. He died in 1987, a terrible loss. [Extract from personal communication received in March 2010 from John Kirby.] Frank and John Kirby and their associate Rodney Lester were pioneers in pharmacy automation and small-object counting technology. In 1967, the Kirbys invented a portable digital tablet counter to count tablets and capsules. With Lester they formed a limited company. In 1970, their invention was patented and put into production in Oldham, England. The tablet counter aided the pharmacy industry with time-consuming manual counting of drug prescriptions. A counting machine consistently counted medications accurately and quickly. This aspect of pharmacy automation was quickly adopted, and innovations emerged every decade to aid the pharmacy industry to deliver medications quickly, safely, and economically. Modern pharmacies have many new options to improve their workflow by using the new technology, and can choose intelligently from the many options available. === Chronology === On 1 January 1971 commercial production of the first portable digital tablet counters in the World began. John Kirby had filed U.K. Patent number GB1358378(A) on 8 September 1970 and U.S. patent number 3789194 on 9 August 1971. These early electronic counters were designed to help pharmacies replace the common (but often inaccurate) practice of counting medications by hand. In 1975, the digital technology was exported to America. In early 1980 a dedicated research, development and production facility was built in Oldham, England at a cost of £500,000. Between 1982 and 1983, two separate development facilities had been created. In America, overseen by Rodney Lester; and in England, overseen by the Kirby brothers. In 1987, Frank Kirby died. In 1989, John Kirby moved his UK facility to Devon, England. A simple to operate machine had been developed to accurately and quickly count prescription medications. Technology improvements soon resulted in a more compact model. The price of such equipment in 1980 was around £1,300. This substantial investment in new technology was a major financial consideration, but the pharmacy community considered the use of a counting machine as a superior method compared to hand-counting medications. These early devices became known as tablet counter, capsule counter, pill counter, or drug counter. The new counting technology replaced manual methods in many industries such as, vitamin and diet supplement manufacturing. Technicians needed a small, affordable device to count and bottle medications. In England and America, the 1980s and 1990s saw new the development of high-speed machines for counting and bottle filling, Like their pharmacy-based counterparts, these industrial units were designed to be fast and simple to operate, yet remain small and cost effective. In America, in the late 1990s/early 2000s a new type of tablet counter appeared. It was simple to use, compact, inexpensive, and had good counting accuracy. At the turn of the millennium technical advances allowed the design of counters with a software verification system. With an onboard computer, displaying photo images of medications to assist the pharmacist or pharmacy technician to verify that the correct medication was being dispensed. In addition, a database for storing all prescriptions that were counted on the device. Between September 2005 and May 2007, American Capital made a major financial investment in Kirby Lester, which then relocated to a larger facility to expand its research and development capabilities. This move added extra space for product research and development facility (R&D). It allowed the opportunity to develop new advanced technology products that met the pharmacy's needs for simple, accurate, and cost-effective ways to dispense prescriptions safely. Pictured here is an early American type of integrated counter and packaging device. This machine was a third generation step in the evolution of pharmacy automated devices. Later models held pre-counted containers of commonly-prescribed medications. == Global variations == In the EU member states legislation was introduced in 1998 which had a major effect on UK Pharmacy operations. It effectively prohibited the use of tablet counters for counting and dispensing bulk packaged tablets. Both usage and sales of the machines in the UK declined rapidly as a result of the introduction of blister packaging for medicines. == Current state of the industry == A tablet counter has become a standard in more than 30,000 sites in 35 countries (as of 2010) (including many non-pharmacy sites, such as manufacturing facilities that use a counting machine as a check for small items). During the 1990s through 2012, numerous new pharmacy automation products came to market. During this timeframe, counting technologies, robotics, workflow management software, and interactive voice recognition (IVR) systems for retail (both chain and independent), outpatient, government, and closed-door pharmacies (mail order and central fill) were all introduced. Additionally, the concept of scalability - of migrating from an entry-level product to the next level of automation (e.g., counting technology to robotics) - was introduced and subsequently launched a new product line in 1997. Pharmacists everywhere are making the switch to automation for its increased speed, greater accuracy, and better security. As the industry evolves and customer expectations grow, automation is becoming less of a luxury and more of a necessity. Especially for independent pharmacies, automation is now a means of keeping up with the competition of large chain pharmacies. == Technological changes and design improvements == Constant developments in technology make the dispensing of prescription medications safer, more accurate and more efficient. In America, in 2008, "next-generation" counting and verification systems were introduced. Based on the counting technology employed in preceding models, later machines included the ability to help the pharmacy operate more effectively. Equipped with a new computer interface to a pharmacy management system, with workflow and inventory software. It also included "checks and balances" to ensure the technician and pharmacist were dispensing the correct medication for each patient. This is something that is important to keep reported correctly when dealing with controlled substances like narcotics. This was a step forward to verify all 100% of prescriptions that were dispensed by pharmacy staff. In America, in 2009, further advanced counters were designed that included the ability to dispense hands-free – a feature that many operators had desired. This allowed pharmacies to automate their most commonly dispensed medications via calibrated cassettes. Thirty of a pharmacy's common medications would now be dispensed automatically. Another new model doubled that throughput via an enclosed robotic mechanism. Robo
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Visualization (graphics)

Visualization (or visualisation in Commonwealth English; see spelling differences), also known as graphics visualization, is any technique for creating images, diagrams, or animations to communicate a message. Visualization through visual imagery has been an effective way to communicate both abstract and concrete ideas since the dawn of humanity. Examples from history include cave paintings, Egyptian hieroglyphs, Greek geometry, and Leonardo da Vinci's revolutionary methods of technical drawing for engineering purposes that actively involve scientific requirements. Visualization today has ever-expanding applications in science, education, engineering (e.g., product visualization), interactive multimedia, medicine, etc. Typical of a visualization application is the field of computer graphics. The invention of computer graphics (and 3D computer graphics) may be the most important development in visualization since the invention of central perspective in the Renaissance period. The development of animation also helped advance visualization. == Overview == The use of visualization to present information is not a new phenomenon. It has been used in maps, scientific drawings, and data plots for over a thousand years. Examples from cartography include Ptolemy's Geographia (2nd century AD), a map of China (1137 AD), and Minard's map (1861) of Napoleon's invasion of Russia a century and a half ago. Most of the concepts learned in devising these images carry over in a straightforward manner to computer visualization. Edward Tufte has written three critically acclaimed books that explain many of these principles. Computer graphics has from its beginning been used to study scientific problems. However, in its early days the lack of graphics power often limited its usefulness. The recent emphasis on visualization started in 1987 with the publication of Visualization in Scientific Computing, a special issue of Computer Graphics. Since then, there have been several conferences and workshops, co-sponsored by the IEEE Computer Society and ACM SIGGRAPH, devoted to the general topic, and special areas in the field, for example volume visualization. Most people are familiar with the digital animations produced to present meteorological data during weather reports on television, though few can distinguish between those models of reality and the satellite photos that are also shown on such programs. TV also offers scientific visualizations when it shows computer drawn and animated reconstructions of road or airplane accidents. Some of the most popular examples of scientific visualizations are computer-generated images that show real spacecraft in action, out in the void far beyond Earth, or on other planets. Dynamic forms of visualization, such as educational animation or timelines, have the potential to enhance learning about systems that change over time. Apart from the distinction between interactive visualizations and animation, the most useful categorization is probably between abstract and model-based scientific visualizations. The abstract visualizations show completely conceptual constructs in 2D or 3D. These generated shapes are completely arbitrary. The model-based visualizations either place overlays of data on real or digitally constructed images of reality or make a digital construction of a real object directly from the scientific data. Scientific visualization is usually done with specialized software, though there are a few exceptions, noted below. Some of these specialized programs have been released as open source software, having very often its origins in universities, within an academic environment where sharing software tools and giving access to the source code is common. There are also many proprietary software packages of scientific visualization tools. Models and frameworks for building visualizations include the data flow models popularized by systems such as AVS, IRIS Explorer, and VTK toolkit, and data state models in spreadsheet systems such as the Spreadsheet for Visualization and Spreadsheet for Images. == Applications == === Scientific visualization === As a subject in computer science, scientific visualization is the use of interactive, sensory representations, typically visual, of abstract data to reinforce cognition, hypothesis building, and reasoning. Scientific visualization is the transformation, selection, or representation of data from simulations or experiments, with an implicit or explicit geometric structure, to allow the exploration, analysis, and understanding of the data. Scientific visualization focuses and emphasizes the representation of higher order data using primarily graphics and animation techniques. It is a very important part of visualization and maybe the first one, as the visualization of experiments and phenomena is as old as science itself. Traditional areas of scientific visualization are flow visualization, medical visualization, astrophysical visualization, and chemical visualization. There are several different techniques to visualize scientific data, with isosurface reconstruction and direct volume rendering being the more common. === Data and information visualization === Data visualization is a related subcategory of visualization dealing with statistical graphics and geospatial data (as in thematic cartography) that is abstracted in schematic form. Information visualization concentrates on the use of computer-supported tools to explore large amount of abstract data. The term "information visualization" was originally coined by the User Interface Research Group at Xerox PARC and included Jock Mackinlay. Practical application of information visualization in computer programs involves selecting, transforming, and representing abstract data in a form that facilitates human interaction for exploration and understanding. Important aspects of information visualization are dynamics of visual representation and the interactivity. Strong techniques enable the user to modify the visualization in real-time, thus affording unparalleled perception of patterns and structural relations in the abstract data in question. === Educational visualization === Educational visualization is using a simulation to create an image of something so it can be taught about. This is very useful when teaching about a topic that is difficult to otherwise see, for example, atomic structure, because atoms are far too small to be studied easily without expensive and difficult to use scientific equipment. === Knowledge visualization === The use of visual representations to transfer knowledge between at least two persons aims to improve the transfer of knowledge by using computer and non-computer-based visualization methods complementarily. Thus properly designed visualization is an important part of not only data analysis but knowledge transfer process, too. Knowledge transfer may be significantly improved using hybrid designs as it enhances information density but may decrease clarity as well. For example, visualization of a 3D scalar field may be implemented using iso-surfaces for field distribution and textures for the gradient of the field. Examples of such visual formats are sketches, diagrams, images, objects, interactive visualizations, information visualization applications, and imaginary visualizations as in stories. While information visualization concentrates on the use of computer-supported tools to derive new insights, knowledge visualization focuses on transferring insights and creating new knowledge in groups. Beyond the mere transfer of facts, knowledge visualization aims to further transfer insights, experiences, attitudes, values, expectations, perspectives, opinions, and estimates in different fields by using various complementary visualizations. See also: picture dictionary, visual dictionary === Product visualization === Product visualization involves visualization software technology for the viewing and manipulation of 3D models, technical drawing and other related documentation of manufactured components and large assemblies of products. It is a key part of product lifecycle management. Product visualization software typically provides high levels of photorealism so that a product can be viewed before it is actually manufactured. This supports functions ranging from design and styling to sales and marketing. Technical visualization is an important aspect of product development. Originally technical drawings were made by hand, but with the rise of advanced computer graphics the drawing board has been replaced by computer-aided design (CAD). CAD-drawings and models have several advantages over hand-made drawings such as the possibility of 3-D modeling, rapid prototyping, and simulation. 3D product visualization promises more interactive experiences for online shoppers, but also challenges retailers to overcome hurdles in the production of 3D content, as large-scale 3D content production can be extremel
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Apptek

Applications Technology (AppTek) is a U.S. company headquartered in McLean, Virginia that specializes in artificial intelligence and machine learning for human language technologies. The company provides both managed and professional services for natural language processing (NLP) technologies including automatic speech recognition (ASR), neural machine translation (MT), natural-language understanding (NLU) and neural speech synthesis. AppTek's Head of Science, Prof. Dr. -Ing Hermann Ney, was awarded the IEEE James L. Flanagan Speech and Audio Processing Award in 2019 and the ISCA Medal for Scientific Achievement in 2021 for his work in natural language processing. == History == AppTek was acquired in 1998 by Lernout & Hauspie (at the time a NASDAQ publicly traded company), AppTek organized a management buy-out and went private again in 2001. In 2014, the company sold its hybrid machine translation technology to eBay and has since rebuilt the platform to modern neural-based approaches for machine translation. In 2020, SOSi acquired non-controlling interest in AppTek and became an exclusive reseller of AppTek products for U.S. federal, state, and local government entities.
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Baby Bundle (app)

Baby Bundle is a parenting mobile app for iPhone and iPad. It was designed to help new parents through pregnancy and the first two years of parenthood. Developed in collaboration with medical experts, it helps track and record the child's development and growth, offers parental advice, manages vaccinations and health check-ups, stores photos and provides baby monitoring services. == History == Baby Bundle was founded in the United Kingdom by brothers, Nick and Anthony von Christierson. Each worked in investment banking prior to developing Baby Bundle, Nick at Greenhill & Co., and Anthony at Goldman Sachs. The idea for the app came when a friend's wife voiced her frustration over having multiple parenting apps on her smartphone. Nick and Anthony left their jobs to create a single app that would include all those features. They conducted market research by interviewing more than 500 parents in the UK and US. It took them a year to build the app, which was named by their mother. Looking for endorsement, they first went to the US in 2013 and partnered with parenting expert and pediatrician Dr. Jennifer Trachtenberg. Baby Bundle was launched in the US and Canadian App Stores in April 2014. In the same month, it became the #1 parenting app in iTunes and was featured by Apple as the #1 Editor's pick across all categories. Mashable called it one of the "Top 5 Can’t Miss Apps." Baby Bundle raised $1.8m seed round in March 2015 to fund development. The money came from a range of angel investors from across the US, UK and Asia. The von Christierson brothers have signed a deal to co-brand the app in the Middle East and expect to launch in Europe and Africa. == Features == Baby Bundle is an app for both the iPhone or iPad and provides smart monitoring tools and trackers for pregnancy and child development. It acts as a growth and daily activity tracker and offers parental advice, manages vaccinations and health check-ups. It has a parenting guide with tips and advice on what to expect when the baby arrives. An interactive forum also lets parents ask questions from others in the community. The app is free and also include paid premium features like the ability to turn two iPhones running into a baby monitor, a cloud service to share the child's data with a spouse and the ability to store data on more than one baby.
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Lucy–Hook coaddition method

The Lucy–Hook coaddition method is an image processing technique for combining sub-stepped astronomical image data onto a finer grid. The method allows the option of resolution and contrast enhancement or the choice of a conservative, re-convolved, output. Tests with very deep Hubble Space Telescope Wide Field and Planetary Camera 2 (WFPC2) imaging data of excellent quality show that these methods can be very effective and allow fine-scale features to be studied better than on the unprocessed images. The Lucy–Hook coaddition method is an extension of the standard Richardson–Lucy deconvolution iterative restoration method. For many purposes it may be more convenient to combine dithered datasets using the Drizzle method.
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Artificial intimacy

Artificial intimacy is a form of human-AI interaction in which an individual will form social connections, emotional bonds, or intimate relationships with various forms of artificial intelligence, including chatbots, virtual assistants, and other artificial entities. Artificially intimate relationships include not only romances, but parasocial relationships with virtual AI characters and the use of griefbots trained on a dead or otherwise lost individual. Artificial intimacy can arise because humans are prone to anthropomorphism. Responses from these AI models are often designed to simulate human interaction. Individuals experiencing artificial intimacy may exhibit attachment, love and commitment to certain AI models, akin to the bonds typically shared between humans. == Causes == === Perceived responsiveness === Robin Dunbar famously proposed that due to emergence of larger groups of humans, vocal communication and language in humans evolved to replace grooming as a means of bonding, arguing that language was a more efficient way to maintain and strengthen social bonds across wider social settings and networks. Further research in this field leads many psychologists to agree that social cognition, affiliative bonding and language in humans are deeply connected. The interpersonal model of intimacy considers communication to be key in affiliative bonding, suggesting that intimacy develops and deepens through open communication between partners in relationship. Specifically, when individuals communicate emotions and perceive their partner as responsive and caring, feelings of closeness and connection are enhanced, building intimacy. Social penetration theory also aligns with the idea of communication being central to intimacy, by explaining how interpersonal relationships develop through gradual increases in self-disclosure. When the benefits of emotional bonding outweigh the costs of vulnerability, individuals will partake in self-disclosure, opening up to one another. Thereby, the literature can be used to provide a proximate explanation for the emergence of artificial intimacy to understand how the phenomenon occurs. Artificial entities are able to mimic interpersonal communication between humans, which in turn can simulate sensations of intimacy within human users though a perceived sense of responsiveness. The relationship between human and AI does not come with the cost of vulnerability or social rejection, which may make self-disclosure easier than with other humans. Altogether, these factors may lead to the experience of anthropomorphism and formation of affiliative relationships. Skjuve et al's interview study on Replika chatbot users further aligns with this explanation, finding that users' perception of chatbots as "accepting, understanding and non-judgmental" facilitated relationship development between the AI and users, and the act of self-disclosure possibly strengthened relationships. Another study on Replika users' reviews and survey results found users perceived chatbots as emotional supportive companions. This evidence further suggests that the perception of artificial entities as capable of empathy and responsiveness in communication facilitate the development of intimate relationships between users and AI. === Loneliness and coping with negative emotions === Research has suggested that humans evolved social bonds as a result of evolutionary pressures that favored cooperation, information exchange and transmission, and group living. Many studies stress the presence of social bonds to be important for human living: research by Baumeister and Leary suggests that humans have a basic psychological need to form and maintain "strong, stable interpersonal relationships", and that a lack of social bonds or sense of belonging leads to negative psychological and physical outcomes. Eisenberger et al's study on the neuroimaging of brain activity suggests that human brains process social rejection and exclusion similarly to physical pain. Furthermore, Song et al's study found that lonely individuals tend to seek more connections in mediated environments, such as online platforms like Facebook. This was suggested to be as a means to reduce their offline loneliness from a lack of in-person interaction, while also fulfilling a need to communicate. Leading on from this, an ultimate explanation for why humans seek the perceived sense of connection from artificial intimacy is to fulfil an evolutionary need for bonding and belonging. Xie et al's study found loneliness to be a driving factor in chatbot interaction. Herbener and Damholdt's study on Danish high school students found that students who sought emotional support or engaged in reciprocal conversations with chatbots were significantly more lonely than their peers, perceived themselves as having less social support, and used the chatbots to cope with negative emotions. The aforementioned notion that chatbots were perceived to have a positive effect on users' negative emotions is also further supported by other studies. Skjuve et al's study found that chatbot relationships may have a positive effect on users' wellbeing. De Freitas et al ran several studies on the effect of chatbots on loneliness, consistently finding evidence suggesting that interaction with chatbots reduces loneliness in users: It was found that existing chatbot users used AI to alleviate loneliness, having an AI companion consistently reduced loneliness over the course of a week, and reductions in loneliness could be explained by chatbot performance—and specifically whether it was able to make users feel heard. Overall the evidence suggests an innate need for bonding evokes feelings of loneliness in users, who turn to artificial intimacy as a low-cost method alleviate these emotions. While many users report positive experiences, some researchers caution that pursuing artificial intimacy may lead to reduced social motivation, social substitution effects, withdrawal from real-life relationships and difficulty discerning reality from fantasy, which may increase longer-term loneliness and isolation. The long-term psychological and societal impacts remain under active investigation.
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Signal-to-noise ratio (imaging)

Signal-to-noise ratio (SNR) is used in imaging to characterize image quality. The sensitivity of a (digital or film) imaging system is typically described in the terms of the signal level that yields a threshold level of SNR. Industry standards define sensitivity in terms of the ISO film speed equivalent, using SNR thresholds (at average scene luminance) of 40:1 for "excellent" image quality and 10:1 for "acceptable" image quality. SNR is sometimes quantified in decibels (dB) of signal power relative to noise power, though in the imaging field the concept of "power" is sometimes taken to be the power of a voltage signal proportional to optical power; so a 20 dB SNR may mean either 10:1 or 100:1 optical power, depending on which definition is in use. == Definition of SNR == Traditionally, SNR is defined to be the ratio of the average signal value μ s i g {\displaystyle \mu _{\mathrm {sig} }} to the standard deviation of the signal σ s i g {\displaystyle \sigma _{\mathrm {sig} }} : S N R = μ s i g σ s i g {\displaystyle \mathrm {SNR} ={\frac {\mu _{\mathrm {sig} }}{\sigma _{\mathrm {sig} }}}} when the signal is an optical intensity, or as the square of this value if the signal and noise are viewed as amplitudes (field quantities).
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Signal transfer function

The signal transfer function (SiTF) is a measure of the signal output versus the signal input of a system such as an infrared system or sensor. There are many general applications of the SiTF. Specifically, in the field of image analysis, it gives a measure of the noise of an imaging system, and thus yields one assessment of its performance. == SiTF evaluation == In evaluating the SiTF curve, the signal input and signal output are measured differentially; meaning, the differential of the input signal and differential of the output signal are calculated and plotted against each other. An operator, using computer software, defines an arbitrary area, with a given set of data points, within the signal and background regions of the output image of the infrared sensor, i.e. of the unit under test (UUT), (see "Half Moon" image below). The average signal and background are calculated by averaging the data of each arbitrarily defined region. A second order polynomial curve is fitted to the data of each line. Then, the polynomial is subtracted from the average signal and background data to yield the new signal and background. The difference of the new signal and background data is taken to yield the net signal. Finally, the net signal is plotted versus the signal input. The signal input of the UUT is within its own spectral response. (e.g. color-correlated temperature, pixel intensity, etc.). The slope of the linear portion of this curve is then found using the method of least squares. == SiTF curve == The net signal is calculated from the average signal and background, as in signal to noise ratio (imaging)#Calculations. The SiTF curve is then given by the signal output data, (net signal data), plotted against the signal input data (see graph of SiTF to the right). All the data points in the linear region of the SiTF curve can be used in the method of least squares to find a linear approximation. Given n {\displaystyle n\,} data points ( x i , y i ) {\displaystyle (x_{i}\,,y_{i}\,)} a best fit line parameterized as y = m x + b {\displaystyle y=mx+b\,} is given by: m = ∑ x i y i n − ∑ x i n ∑ y i n ∑ x i 2 n − ( ∑ x i n ) 2 b = ∑ y i n − m ∑ x i n {\displaystyle m={\frac {{\frac {\sum x_{i}y_{i}}{n}}-{\frac {\sum x_{i}}{n}}{\frac {\sum y_{i}}{n}}}{{\frac {\sum x_{i}^{2}}{n}}-({\frac {\sum x_{i}}{n}})^{2}}}\qquad \qquad b={\frac {\sum y_{i}}{n}}-m{\frac {\sum x_{i}}{n}}}
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