AI Chatbot Companion

AI Chatbot Companion — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

  • Anna Becker

    Anna Becker

    Anna Becker is an Israeli researcher known in the field of artificial intelligence and computer science within the financial field. == Early life and education == Becker was born in Russia and immigrated to Israel at 16 after graduating from a school in Moscow. At 17, she began her studies at Technion – Israel Institute of Technology. During her master's degree in computer science, she taught first-year students of the same course, and at 27, Becker completed her PhD in Computer Science and Artificial Intelligence. == Career == While pursuing her PhD, Becker resolved an NP-complete approximation algorithm that had been unresolved for over twenty years. This made her a recognized scholar in the field. After completing her PhD, she developed an approximation technique by a factor of two. This technique is widely used today in operating systems, database systems, and VLSI chip designs. She then founded and sold Strategy Runner, a fintech software. After this, she founded EndoTech, an algorithmic trading platform based on artificial intelligence and machine learning. EndoTech's trading strategies have been operating in live cryptocurrency markets since 2017. The platform's BTC Alpha strategy has reported an average annual return of 163% on fixed capital over eight years of live operation, with a maximum drawdown of 14% and a trade accuracy rate of approximately 83%. In 2026, EndoTech entered a partnership with Bit1 Exchange to make its BTC Alpha and ETH Alpha copy trading strategies accessible to retail investors with no minimum deposit requirement, through a full-custody model in which user funds remain in their own exchange wallets at all times.As of 2023, Becker is working on Fianchetto Fund, an AI-based investing analysis platform. Becker has also co-authored a book on Bayesian networks, which has been published widely in the field of computer science and artificial intelligence.

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  • Operational taxonomic unit

    Operational taxonomic unit

    An operational taxonomic unit (OTU) is an operational definition used to classify groups of closely related individuals. The term was originally introduced in 1963 by Robert R. Sokal and Peter H. A. Sneath in the context of numerical taxonomy, where an "operational taxonomic unit" is simply the group of organisms currently being studied. In this sense, an OTU is a pragmatic definition to group individuals by similarity, equivalent to but not necessarily in line with classical Linnaean taxonomy or modern evolutionary taxonomy. Nowadays, however, the term is commonly used in a different context and refers to clusters of (uncultivated or unknown) organisms, grouped by DNA sequence similarity of a specific taxonomic marker gene (originally coined as mOTU; molecular OTU). In other words, OTUs are pragmatic proxies for "species" at different taxonomic levels, in the absence of traditional systems of biological classification as are available for macroscopic organisms. For several years, OTUs have been the most commonly used units of diversity, especially when analysing small subunit 16S (for prokaryotes) or 18S rRNA (for eukaryotes) marker gene sequence datasets. == Molecular OTU by clustering of marker gene sequences == In the approach represented by DNA barcoding, a particular locus is chosen to be used as the marker gene for classification. This locus should be universally present in the scope selected, variable enough to be different among close-related species, and be flanked by conservative sequences that allow for easy amplification and detection. There are databases containing sequences for such marker genes from many different species, allowing for comparison. (Sometimes only using one locus does not provide sufficient resolution, so multiple marker genes are used. This is the case for plants, where rbcL+matK is common.) Sequences obtained this way can be clustered according to their similarity to one another, and operational taxonomic units are defined based on the similarity threshold set by the researcher. The exact threshold depends on the taxa in question and the mutational rates of the selected locus in the taxon. 97–99% are commonly used, but "it is now recognized to be somewhat arbitrary as sequence variation within and among species varies across taxa". 100% similarity (fully identical) is also common, also known as single variants. It remains debatable how well this commonly used method recapitulates true microbial species phylogeny or ecology. Although OTUs can be calculated differently when using different algorithms or thresholds, research by Schmidt et al. (2014) demonstrated that 16S-derived microbial OTUs were generally ecologically consistent across habitats and several clustering approaches. The number of OTUs defined may be inflated due to errors in DNA sequencing. === OTU clustering approaches === There are three main approaches to clustering OTUs: De novo, for which the clustering is based on similarities between sequencing reads. Closed-reference, for which the clustering is performed against a reference database of sequences. Open-reference, where clustering is first performed against a reference database of sequences, then any remaining sequences that could not be mapped to the reference are clustered de novo. Using a reference provides taxonomic context for the OTUs found. Alternatively, taxonomic context can be found after the construction of clusters by comparing representative sequences from clusters against a reference database. There are also specialized classifiers for this purpose which are much faster than naive comparison using BLAST. === OTU clustering algorithms === Hierarchical clustering algorithms (HCA): uclust & cd-hit & ESPRIT Bayesian clustering: CROP == Molecular OTU by other methods == In addition to similarity-based grouping, marker gene sequences can be sorted into OTUs using molecular phylogeny, k-mer composition, or hybrid methods combining these methods with similarity. There are also Bayesian tree-less methods and machine learning approaches. Using phylogeny often involves manually assigning terminal clades or single nodes to an OTU, so this is usually only done for refinement. Genome skimming can be used to obtain high-copy DNA without the need to choose marker genes or to design PCR primers for the chosen genes. It can provide fairly good coverage of organelle DNA and repetitive elements such as ribosomal DNA, both of which can be used like marker genes in OTU analysis. Whole-genome sequencing is more expensive and involves the production and processing of more data. By considering the entire genome, many (sometimes over 100) marker genes can be used at the same time, producing highly resolved phylogenies that correctly identify problematic taxa. It is also possible to use entire genomes for OTU assignment. For example, genomes from different bacterial species almost always have an average nucleotide identity lower than 95%, a fact that can be used to define new OTUs (and likely new species).

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  • Premature convergence

    Premature convergence

    Premature convergence is an unwanted effect in evolutionary algorithms (EA), a metaheuristic that mimics the basic principles of biological evolution as a computer algorithm for solving an optimization problem. The effect means that the population of an EA has converged too early, resulting in being suboptimal. In this context, the parental solutions, through the aid of genetic operators, are not able to generate offspring that are superior to, or outperform, their parents. Premature convergence is a common problem found in evolutionary algorithms, as it leads to a loss, or convergence of, a large number of alleles, subsequently making it very difficult to search for a specific gene in which the alleles were present. An allele is considered lost if, in a population, a gene is present, where all individuals are sharing the same value for that particular gene. An allele is, as defined by De Jong, considered to be a converged allele, when 95% of a population share the same value for a certain gene. == Strategies for preventing premature convergence == Strategies to regain genetic variation can be: a mating strategy called incest prevention, uniform crossover, mimicking sexual selection, favored replacement of similar individuals (preselection or crowding), segmentation of individuals of similar fitness (fitness sharing), increasing population size niche and specie The genetic variation can also be regained by mutation though this process is highly random. A general strategy to reduce the risk of premature convergence is to use structured populations instead of the commonly used panmictic ones. == Identification of the occurrence of premature convergence == It is hard to determine when premature convergence has occurred, and it is equally hard to predict its presence in the future. One measure is to use the difference between the average and maximum fitness values, as used by Patnaik & Srinivas, to then vary the crossover and mutation probabilities. Population diversity is another measure which has been extensively used in studies to measure premature convergence. However, although it has been widely accepted that a decrease in the population diversity directly leads to premature convergence, there have been little studies done on the analysis of population diversity. In other words, by using the term population diversity, the argument for a study in preventing premature convergence lacks robustness, unless specified what their definition of population diversity is. There are models to counter the effect and risk of premature convergence that do not compromise core GA parameters like population size, mutation rate, and other core mechanisms. These models were inspired by biological ecology, where genetic interactions are limited by external mechanisms such as spatial topologies or speciation. These ecological models, such as the Eco-GA, adopt diffusion-based strategies to improve the robustness of GA runs and increase the likelihood of reaching near-global optima. == Causes for premature convergence == There are a number of presumed or hypothesized causes for the occurrence of premature convergence. === Self-adaptive mutations === Rechenberg introduced the idea of self-adaptation of mutation distributions in evolution strategies. According to Rechenberg, the control parameters for these mutation distributions evolved internally through self-adaptation, rather than predetermination. He called it the 1/5-success rule of evolution strategies (1 + 1)-ES: The step size control parameter would be increased by some factor if the relative frequency of positive mutations through a determined period of time is larger than 1/5, vice versa if it is smaller than 1/5. Self-adaptive mutations may very well be one of the causes for premature convergence. Accurately locating of optima can be enhanced by self-adaptive mutation, as well as accelerating the search for this optima. This has been widely recognized, though the mechanism's underpinnings of this have been poorly studied, as it is often unclear whether the optima is found locally or globally. Self-adaptive methods can cause global convergence to global optimum, provided that the selection methods used are using elitism, as well as that the rule of self-adaptation doesn't interfere with the mutation distribution, which has the property of ensuring a positive minimum probability when hitting a random subset. This is for non-convex objective functions with sets that include bounded lower levels of non-zero measurements. A study by Rudolph suggests that self-adaption mechanisms among elitist evolution strategies do resemble the 1/5-success rule, and could very well get caught by a local optimum that include a positive probability. === Panmictic populations === Most EAs use unstructured or panmictic populations where basically every individual in the population is eligible for mate selection based on fitness. Thus, The genetic information of an only slightly better individual can spread in a population within a few generations, provided that no better other offspring is produced during this time. Especially in comparatively small populations, this can quickly lead to a loss of genotypic diversity and thus to premature convergence. A well-known countermeasure is to switch to alternative population models which introduce substructures into the population that preserve genotypic diversity over a longer period of time and thus counteract the tendency towards premature convergence. This has been shown for various EAs such as genetic algorithms, the evolution strategy, other EAs or memetic algorithms.

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  • Blockmodeling

    Blockmodeling

    Blockmodeling is a set or a coherent framework, that is used for analyzing social structure and also for setting procedure(s) for partitioning (clustering) social network's units (nodes, vertices, actors), based on specific patterns, which form a distinctive structure through interconnectivity. It is primarily used in statistics, machine learning and network science. As an empirical procedure, blockmodeling assumes that all the units in a specific network can be grouped together to such extent to which they are equivalent. Regarding equivalency, it can be structural, regular or generalized. Using blockmodeling, a network can be analyzed using newly created blockmodels, which transforms large and complex network into a smaller and more comprehensible one. At the same time, the blockmodeling is used to operationalize social roles. While some contend that the blockmodeling is just clustering methods, Bonacich and McConaghy state that "it is a theoretically grounded and algebraic approach to the analysis of the structure of relations". Blockmodeling's unique ability lies in the fact that it considers the structure not just as a set of direct relations, but also takes into account all other possible compound relations that are based on the direct ones. The principles of blockmodeling were first introduced by Francois Lorrain and Harrison C. White in 1971. Blockmodeling is considered as "an important set of network analytic tools" as it deals with delineation of role structures (the well-defined places in social structures, also known as positions) and the discerning the fundamental structure of social networks. According to Batagelj, the primary "goal of blockmodeling is to reduce a large, potentially incoherent network to a smaller comprehensible structure that can be interpreted more readily". Blockmodeling was at first used for analysis in sociometry and psychometrics, but has now spread also to other sciences. == Definition == A network as a system is composed of (or defined by) two different sets: one set of units (nodes, vertices, actors) and one set of links between the units. Using both sets, it is possible to create a graph, describing the structure of the network. During blockmodeling, the researcher is faced with two problems: how to partition the units (e.g., how to determine the clusters (or classes), that then form vertices in a blockmodel) and then how to determine the links in the blockmodel (and at the same time the values of these links). In the social sciences, the networks are usually social networks, composed of several individuals (units) and selected social relationships among them (links). Real-world networks can be large and complex; blockmodeling is used to simplify them into smaller structures that can be easier to interpret. Specifically, blockmodeling partitions the units into clusters and then determines the ties among the clusters. At the same time, blockmodeling can be used to explain the social roles existing in the network, as it is assumed that the created cluster of units mimics (or is closely associated with) the units' social roles. Blockmodeling can thus be defined as a set of approaches for partitioning units into clusters (also known as positions) and links into blocks, which are further defined by the newly obtained clusters. A block (also blockmodel) is defined as a submatrix, that shows interconnectivity (links) between nodes, present in the same or different clusters. Each of these positions in the cluster is defined by a set of (in)direct ties to and from other social positions. These links (connections) can be directed or undirected; there can be multiple links between the same pair of objects or they can have weights on them. If there are not any multiple links in a network, it is called a simple network. A matrix representation of a graph is composed of ordered units, in rows and columns, based on their names. The ordered units with similar patterns of links are partitioned together in the same clusters. Clusters are then arranged together so that units from the same clusters are placed next to each other, thus preserving interconnectivity. In the next step, the units (from the same clusters) are transformed into a blockmodel. With this, several blockmodels are usually formed, one being core cluster and others being cohesive; a core cluster is always connected to cohesive ones, while cohesive ones cannot be linked together. Clustering of nodes is based on the equivalence, such as structural and regular. The primary objective of the matrix form is to visually present relations between the persons included in the cluster. These ties are coded dichotomously (as present or absent), and the rows in the matrix form indicate the source of the ties, while the columns represent the destination of the ties. Equivalence can have two basic approaches: the equivalent units have the same connection pattern to the same neighbors or these units have same or similar connection pattern to different neighbors. If the units are connected to the rest of network in identical ways, then they are structurally equivalent. Units can also be regularly equivalent, when they are equivalently connected to equivalent others. With blockmodeling, it is necessary to consider the issue of results being affected by measurement errors in the initial stage of acquiring the data. == Different approaches == Regarding what kind of network is undergoing blockmodeling, a different approach is necessary. Networks can be one–mode or two–mode. In the former all units can be connected to any other unit and where units are of the same type, while in the latter the units are connected only to the unit(s) of a different type. Regarding relationships between units, they can be single–relational or multi–relational networks. Further more, the networks can be temporal or multilevel and also binary (only 0 and 1) or signed (allowing negative ties)/values (other values are possible) networks. Different approaches to blockmodeling can be grouped into two main classes: deterministic blockmodeling and stochastic blockmodeling approaches. Deterministic blockmodeling is then further divided into direct and indirect blockmodeling approaches. Among direct blockmodeling approaches are: structural equivalence and regular equivalence. Structural equivalence is a state, when units are connected to the rest of the network in an identical way(s), while regular equivalence occurs when units are equally related to equivalent others (units are not necessarily sharing neighbors, but have neighbour that are themselves similar). Indirect blockmodeling approaches, where partitioning is dealt with as a traditional cluster analysis problem (measuring (dis)similarity results in a (dis)similarity matrix), are: conventional blockmodeling, generalized blockmodeling: generalized blockmodeling of binary networks, generalized blockmodeling of valued networks and generalized homogeneity blockmodeling, prespecified blockmodeling. According to Brusco and Steinley (2011), the blockmodeling can be categorized (using a number of dimensions): deterministic or stochastic blockmodeling, one–mode or two–mode networks, signed or unsigned networks, exploratory or confirmatory blockmodeling. == Blockmodels == Blockmodels (sometimes also block models) are structures in which: vertices (e.g., units, nodes) are assembled within a cluster, with each cluster identified as a vertex; from such vertices a graph can be constructed; combinations of all the links (ties), represented in a block as a single link between positions, while at the same time constructing one tie for each block. In a case, when there are no ties in a block, there will be no ties between the two positions that define the block. Computer programs can partition the social network according to pre-set conditions. When empirical blocks can be reasonably approximated in terms of ideal blocks, such blockmodels can be reduced to a blockimage, which is a representation of the original network, capturing its underlying 'functional anatomy'. Thus, blockmodels can "permit the data to characterize their own structure", and at the same time not seek to manifest a preconceived structure imposed by the researcher. Blockmodels can be created indirectly or directly, based on the construction of the criterion function. Indirect construction refers to a function, based on "compatible (dis)similarity measure between paris of units", while the direct construction is "a function measuring the fit of real blocks induced by a given clustering to the corresponding ideal blocks with perfect relations within each cluster and between clusters according to the considered types of connections (equivalence)". === Types === Blockmodels can be specified regarding the intuition, substance or the insight into the nature of the studied network; this can result in such models as follows: parent-child role systems, organizational hierarchies, systems of

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  • Niki.ai

    Niki.ai

    Niki was an artificial intelligence company headquartered in Bangalore, Karnataka. It was founded in May 2015 by IIT Kharagpur graduates Sachin Jaiswal, Keshav Prawasi, Shishir Modi, and Nitin Babel. The Niki android app was launched for a limited beta in June 2015, then released for public during YourStory's TechSparks 2015, and is a Tech30 company. The company raised an undisclosed amount in seed funding from Unilazer Ventures, a Mumbai-based VC firm founded by Ronnie Screwvala, in October 2015. This was followed by another seed funding round by Ratan Tata in May 2016. The company then raised US$2 million in Series A round of funding from SAP.iO, existing investors and some US and German-based investors, among others. Niki.ai shut down in October 2021 as per media reports. Website not working. == Product == The product is an artificial intelligence-powered chatbot which works as an intelligent personal assistant, named Niki. Leveraging natural language processing and machine learning, Niki presents a chat-based natural language user interface to the users where they can interact with Niki in their natural language. Niki understands how users chat in India, deciphers the words, in the context of product/services that they would like to purchase, and comes up with apt recommendations. Initially, it was only available on the Android platform as a mobile app. The company has expanded its operations to the Facebook Messenger and Apple iOS platforms. The company aims to soon be present on more messaging platforms like Slack and WhatsApp. The company currently provides 20+ services to over 2 million consumers, covering a wide spectrum ranging from utility services like mobile recharge, bill payments, travel services like cabs, buses, hotels and entertainment services like movies and events. Services such as flights and healthcare are also planned. == Partnerships == In September 2017, Infosys Finacle joined with Niki.ai to provide chat-based service to banking customers. In August 2017, Niki partnered with LazyPay to enable a 'buy now, pay later' feature for its users.

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  • Handwriting recognition

    Handwriting recognition

    Handwriting recognition (HWR), also known as handwritten text recognition (HTR), is the ability of a computer to receive and interpret intelligible handwritten input from sources such as paper documents, photographs, touch-screens and other devices. The image of the written text may be sensed "off line" from a piece of paper by optical scanning (optical character recognition) or intelligent word recognition. Alternatively, the movements of the pen tip may be sensed "on line", for example by a pen-based computer screen surface, a generally easier task as there are more clues available. A handwriting recognition system handles formatting, performs correct segmentation into characters, and finds the most possible words. == Offline recognition == Offline handwriting recognition involves the automatic conversion of text in an image into letter codes that are usable within computer and text-processing applications. The data obtained by this form is regarded as a static representation of handwriting. Offline handwriting recognition is comparatively difficult, as different people have different handwriting styles. And, as of today, OCR engines are primarily focused on machine printed text and ICR for hand "printed" (written in capital letters) text. === Traditional techniques === ==== Character extraction ==== Offline character recognition often involves scanning a form or document. This means the individual characters contained in the scanned image will need to be extracted. Tools exist that are capable of performing this step. However, there are several common imperfections in this step. The most common is when characters that are connected are returned as a single sub-image containing both characters. This causes a major problem in the recognition stage. Yet many algorithms are available that reduce the risk of connected characters. ==== Character recognition ==== After individual characters have been extracted, a recognition engine is used to identify the corresponding computer character. Several different recognition techniques are currently available. ===== Feature extraction ===== Feature extraction works in a similar fashion to neural network recognizers. However, programmers must manually determine the properties they feel are important. This approach gives the recognizer more control over the properties used in identification. Yet any system using this approach requires substantially more development time than a neural network because the properties are not learned automatically. === Modern techniques === Where traditional techniques focus on segmenting individual characters for recognition, modern techniques focus on recognizing all the characters in a segmented line of text. Particularly they focus on machine learning techniques that are able to learn visual features, avoiding the limiting feature engineering previously used. State-of-the-art methods use convolutional networks to extract visual features over several overlapping windows of a text line image which a recurrent neural network uses to produce character probabilities. == Online recognition == Online handwriting recognition involves the automatic conversion of text as it is written on a special digitizer or PDA, where a sensor picks up the pen-tip movements as well as pen-up/pen-down switching. This kind of data is known as digital ink and can be regarded as a digital representation of handwriting. The obtained signal is converted into letter codes that are usable within computer and text-processing applications. The elements of an online handwriting recognition interface typically include: a pen or stylus for the user to write with a touch sensitive surface, which may be integrated with, or adjacent to, an output display. a software application which interprets the movements of the stylus across the writing surface, translating the resulting strokes into digital text. The process of online handwriting recognition can be broken down into a few general steps: preprocessing, feature extraction and classification The purpose of preprocessing is to discard irrelevant information in the input data, that can negatively affect the recognition. This concerns speed and accuracy. Preprocessing usually consists of binarization, normalization, sampling, smoothing and denoising. The second step is feature extraction. Out of the two- or higher-dimensional vector field received from the preprocessing algorithms, higher-dimensional data is extracted. The purpose of this step is to highlight important information for the recognition model. This data may include information like pen pressure, velocity or the changes of writing direction. The last big step is classification. In this step, various models are used to map the extracted features to different classes and thus identifying the characters or words the features represent. === Hardware === Commercial products incorporating handwriting recognition as a replacement for keyboard input were introduced in the early 1980s. Examples include handwriting terminals such as the Pencept Penpad and the Inforite point-of-sale terminal. With the advent of the large consumer market for personal computers, several commercial products were introduced to replace the keyboard and mouse on a personal computer with a single pointing/handwriting system, such as those from Pencept, CIC and others. The first commercially available tablet-type portable computer was the Write-Top from Linus Technologies, released in July 1988. Its operating system was based on MS-DOS. In the early 1990s, hardware makers including NCR, IBM and EO released tablet computers running the PenPoint operating system developed by GO Corp. PenPoint used handwriting recognition and gestures throughout and provided the facilities to third-party software. IBM's tablet computer was the first to use the ThinkPad name and used IBM's handwriting recognition. This recognition system was later ported to Microsoft Windows for Pen Computing, and IBM's Pen for OS/2. None of these were commercially successful. Advancements in electronics allowed the computing power necessary for handwriting recognition to fit into a smaller form factor than tablet computers, and handwriting recognition is often used as an input method for hand-held PDAs. The first PDA to provide written input was the Apple Newton, which exposed the public to the advantage of a streamlined user interface. However, the device was not a commercial success, owing to the unreliability of the software, which tried to learn a user's writing patterns. By the time of the release of the Newton OS 2.0, wherein the handwriting recognition was greatly improved, including unique features still not found in current recognition systems such as modeless error correction, the largely negative first impression had been made. After discontinuation of Apple Newton, the feature was incorporated in Mac OS X 10.2 and later as Inkwell. Palm later launched a successful series of PDAs based on the Graffiti recognition system. Graffiti improved usability by defining a set of "unistrokes", or one-stroke forms, for each character. This narrowed the possibility for erroneous input, although memorization of the stroke patterns did increase the learning curve for the user. The Graffiti handwriting recognition was found to infringe on a patent held by Xerox, and Palm replaced Graffiti with a licensed version of the CIC handwriting recognition which, while also supporting unistroke forms, pre-dated the Xerox patent. The court finding of infringement was reversed on appeal, and then reversed again on a later appeal. The parties involved subsequently negotiated a settlement concerning this and other patents. A Tablet PC is a notebook computer with a digitizer tablet and a stylus, which allows a user to handwrite text on the unit's screen. The operating system recognizes the handwriting and converts it into text. Windows Vista and Windows 7 include personalization features that learn a user's writing patterns or vocabulary for English, Japanese, Chinese Traditional, Chinese Simplified and Korean. The features include a "personalization wizard" that prompts for samples of a user's handwriting and uses them to retrain the system for higher accuracy recognition. This system is distinct from the less advanced handwriting recognition system employed in its Windows Mobile OS for PDAs. Although handwriting recognition is an input form that the public has become accustomed to, it has not achieved widespread use in either desktop computers or laptops. It is still generally accepted that keyboard input is both faster and more reliable. As of 2006, many PDAs offer handwriting input, sometimes even accepting natural cursive handwriting, but accuracy is still a problem, and some people still find even a simple on-screen keyboard more efficient. === Software === Early software could understand print handwriting where the characters were separated; however, cursive handwriting

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  • Multi-surface method

    Multi-surface method

    The multi-surface method (MSM) is a form of decision making using the concept of piecewise-linear separability of datasets to categorize data. == Introduction == Two datasets are linearly separable if their convex hulls do not intersect. The method may be formulated as a feedforward neural network with weights that are trained via linear programming. Comparisons between neural networks trained with the MSM versus backpropagation show MSM is better able to classify data. The decision problem associated linear program for the MSM is NP-complete. == Mathematical formulation == Given two finite disjoint point sets A , B ∈ R n {\displaystyle {\mathcal {A,B}}\in \mathbb {R} ^{n}} , find a discriminant, f : R n → R {\displaystyle f:\mathbb {R} ^{n}\to \mathbb {R} } such that f ( A ) > 0 , f ( B ) ≤ 0 {\displaystyle f({\mathcal {A}})>0,f({\mathcal {B}})\leq 0} . If the intersection of convex hulls of the two sets is the empty set, then it is possible to use a single linear program to obtain a linear discriminant of the form, f ( x ) = c x + γ {\displaystyle f(x)=cx+\gamma } . Usually, in real applications, the sets' convex hulls do intersect, and a (often non-convex) piecewise-linear discriminant can be used, through the use of several linear programs.

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  • Generalized iterative scaling

    Generalized iterative scaling

    In statistics, generalized iterative scaling (GIS) and improved iterative scaling (IIS) are two early algorithms used to fit log-linear models, notably multinomial logistic regression (MaxEnt) classifiers and extensions of it such as MaxEnt Markov models and conditional random fields. These algorithms have been largely surpassed by gradient-based methods such as L-BFGS and coordinate descent algorithms.

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  • Computer audition

    Computer audition

    Computer audition (CA) or machine listening is the general field of study of algorithms and systems for audio interpretation by machines. Since the notion of what it means for a machine to "hear" is very broad and somewhat vague, computer audition attempts to bring together several disciplines that originally dealt with specific problems or had a concrete application in mind. The engineer Paris Smaragdis, interviewed in Technology Review, talks about these systems — "software that uses sound to locate people moving through rooms, monitor machinery for impending breakdowns, or activate traffic cameras to record accidents." Inspired by models of human audition, CA deals with questions of representation, transduction, grouping, use of musical knowledge and general sound semantics for the purpose of performing intelligent operations on audio and music signals by the computer. Technically this requires a combination of methods from the fields of signal processing, auditory modelling, music perception and cognition, pattern recognition, and machine learning, as well as more traditional methods of artificial intelligence for musical knowledge representation. == Applications == Like computer vision versus image processing, computer audition versus audio engineering deals with understanding of audio rather than processing. It also differs from problems of speech understanding by machine since it deals with general audio signals, such as natural sounds and musical recordings. Applications of computer audition are widely varying, and include search for sounds, genre recognition, acoustic monitoring, music transcription, score following, audio texture, music improvisation, emotion in audio and so on. == Related disciplines == Computer Audition overlaps with the following disciplines: Music information retrieval: methods for search and analysis of similarity between music signals. Auditory scene analysis: understanding and description of audio sources and events. Computational musicology and mathematical music theory: use of algorithms that employ musical knowledge for analysis of music data. Computer music: use of computers in creative musical applications. Machine musicianship: audition driven interactive music systems. == Areas of study == Since audio signals are interpreted by the human ear–brain system, that complex perceptual mechanism should be simulated somehow in software for "machine listening". In other words, to perform on par with humans, the computer should hear and understand audio content much as humans do. Analyzing audio accurately involves several fields: electrical engineering (spectrum analysis, filtering, and audio transforms); artificial intelligence (machine learning and sound classification); psychoacoustics (sound perception); cognitive sciences (neuroscience and artificial intelligence); acoustics (physics of sound production); and music (harmony, rhythm, and timbre). Furthermore, audio transformations such as pitch shifting, time stretching, and sound object filtering, should be perceptually and musically meaningful. For best results, these transformations require perceptual understanding of spectral models, high-level feature extraction, and sound analysis/synthesis. Finally, structuring and coding the content of an audio file (sound and metadata) could benefit from efficient compression schemes, which discard inaudible information in the sound. Computational models of music and sound perception and cognition can lead to a more meaningful representation, a more intuitive digital manipulation and generation of sound and music in musical human-machine interfaces. The study of CA could be roughly divided into the following sub-problems: Representation: signal and symbolic. This aspect deals with time-frequency representations, both in terms of notes and spectral models, including pattern playback and audio texture. Feature extraction: sound descriptors, segmentation, onset, pitch and envelope detection, chroma, and auditory representations. Musical knowledge structures: analysis of tonality, rhythm, and harmonies. Sound similarity: methods for comparison between sounds, sound identification, novelty detection, segmentation, and clustering. Sequence modeling: matching and alignment between signals and note sequences. Source separation: methods of grouping of simultaneous sounds, such as multiple pitch detection and time-frequency clustering methods. Auditory cognition: modeling of emotions, anticipation and familiarity, auditory surprise, and analysis of musical structure. Multi-modal analysis: finding correspondences between textual, visual, and audio signals. === Representation issues === Computer audition deals with audio signals that can be represented in a variety of fashions, from direct encoding of digital audio in two or more channels to symbolically represented synthesis instructions. Audio signals are usually represented in terms of analogue or digital recordings. Digital recordings are samples of acoustic waveform or parameters of audio compression algorithms. One of the unique properties of musical signals is that they often combine different types of representations, such as graphical scores and sequences of performance actions that are encoded as MIDI files. Since audio signals usually comprise multiple sound sources, then unlike speech signals that can be efficiently described in terms of specific models (such as source-filter model), it is hard to devise a parametric representation for general audio. Parametric audio representations usually use filter banks or sinusoidal models to capture multiple sound parameters, sometimes increasing the representation size in order to capture internal structure in the signal. Additional types of data that are relevant for computer audition are textual descriptions of audio contents, such as annotations, reviews, and visual information in the case of audio-visual recordings. === Features === Description of contents of general audio signals usually requires extraction of features that capture specific aspects of the audio signal. Generally speaking, one could divide the features into signal or mathematical descriptors such as energy, description of spectral shape etc., statistical characterization such as change or novelty detection, special representations that are better adapted to the nature of musical signals or the auditory system, such as logarithmic growth of sensitivity (bandwidth) in frequency or octave invariance (chroma). Since parametric models in audio usually require very many parameters, the features are used to summarize properties of multiple parameters in a more compact or salient representation. === Musical knowledge === Finding specific musical structures is possible by using musical knowledge as well as supervised and unsupervised machine learning methods. Examples of this include detection of tonality according to distribution of frequencies that correspond to patterns of occurrence of notes in musical scales, distribution of note onset times for detection of beat structure, distribution of energies in different frequencies to detect musical chords and so on. === Sound similarity and sequence modeling === Comparison of sounds can be done by comparison of features with or without reference to time. In some cases an overall similarity can be assessed by close values of features between two sounds. In other cases when temporal structure is important, methods of dynamic time warping need to be applied to "correct" for different temporal scales of acoustic events. Finding repetitions and similar sub-sequences of sonic events is important for tasks such as texture synthesis and machine improvisation. === Source separation === Since one of the basic characteristics of general audio is that it comprises multiple simultaneously sounding sources, such as multiple musical instruments, people talking, machine noises or animal vocalization, the ability to identify and separate individual sources is very desirable. Unfortunately, there are no methods that can solve this problem in a robust fashion. Existing methods of source separation rely sometimes on correlation between different audio channels in multi-channel recordings. The ability to separate sources from stereo signals requires different techniques than those usually applied in communications where multiple sensors are available. Other source separation methods rely on training or clustering of features in mono recording, such as tracking harmonically related partials for multiple pitch detection. Some methods, before explicit recognition, rely on revealing structures in data without knowing the structures (like recognizing objects in abstract pictures without attributing them meaningful labels) by finding the least complex data representations, for instance describing audio scenes as generated by a few tone patterns and their trajectories (polyphonic voices) and acoustical contours drawn by a tone (c

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  • Julia (programming language)

    Julia (programming language)

    Julia is a dynamic general-purpose programming language. As a high-level language, distinctive aspects of Julia's design include a type system with parametric polymorphism, the use of multiple dispatch as a core programming paradigm, just-in-time compilation and a parallel garbage collection implementation. Notably, Julia does not support classes with encapsulated methods but instead relies on the types of all of a function's arguments to determine which method will be called. By default, Julia is run similarly to scripting languages, using its runtime, and allows for interactions, but Julia programs can also be compiled to small binary standalone executables (or to small libraries for e.g. Python), with e.g. the JuliaC.jl compiler. Julia programs can reuse libraries from other languages, and vice versa. Julia has interoperability with C, C++, Fortran, Rust, Python, and R. Additionally, some Julia packages have bindings to be used from Python and R as libraries. Julia is supported by programmer tools like IDEs (see below) and by notebooks like Pluto.jl, Jupyter, and since 2025, Google Colab officially supports Julia natively. Julia is sometimes used in embedded systems (e.g. has been used in a satellite in space on a Raspberry Pi Compute Module 4; 64-bit Pis work best with Julia, and Julia is supported in Raspbian). == History == Work on Julia began in 2009, when Jeff Bezanson, Stefan Karpinski, Viral B. Shah, and Alan Edelman set out to create a free language that was both high-level and fast. On 14 February 2012, the team launched a website with a blog post explaining the language's mission. In an interview with InfoWorld in April 2012, Karpinski said about the name of the language, Julia: "There's no good reason, really. It just seemed like a pretty name." Bezanson said he chose the name on the recommendation of a friend, then years later wrote: Maybe julia stands for "Jeff's uncommon lisp is automated"? Julia's syntax is stable, since version 1.0 in 2018, and Julia has a backward compatibility guarantee for 1.x and also a stability promise for the documented (stable) API, while in the years before in the early development prior to 0.7 the syntax (and semantics) was changed in new versions. All of the (registered package) ecosystem uses the new and improved syntax, and in most cases relies on new APIs that have been added regularly, and in some cases minor additional syntax added in a forward compatible way e.g. in Julia 1.7. In the 10 years since the 2012 launch of pre-1.0 Julia, the community has grown. The Julia package ecosystem has over 11.8 million lines of code (including docs and tests). The JuliaCon academic conference for Julia users and developers has been held annually since 2014 with JuliaCon2020 welcoming over 28,900 unique viewers, and then JuliaCon2021 breaking all previous records (with more than 300 JuliaCon2021 presentations available for free on YouTube, up from 162 the year before), and 43,000 unique viewers during the conference. Three of the Julia co-creators are the recipients of the 2019 James H. Wilkinson Prize for Numerical Software (awarded every four years) "for the creation of Julia, an innovative environment for the creation of high-performance tools that enable the analysis and solution of computational science problems." Also, Alan Edelman, professor of applied mathematics at MIT, has been selected to receive the 2019 IEEE Computer Society Sidney Fernbach Award "for outstanding breakthroughs in high-performance computing, linear algebra, and computational science and for contributions to the Julia programming language." Version 0.3 was released in August 2014. Both Julia 0.7 and version 1.0 were released on 8 August 2018. Julia 1.4 added syntax for generic array indexing to handle e.g. 0-based arrays. The memory model was also changed. Julia 1.5 released in August 2020 added record and replay debugging support, for Mozilla's rr tool. The release changed the behavior in the REPL (to soft scope) to the one used in Jupyter, but keeps full compatible with non-REPL code (that retains hard scope). Julia 1.6 was the largest release since 1.0, and it was the long-term support (LTS) version for the longest time. Since Julia 1.7 development is back to time-based releases, and it was released in November 2021 with e.g. a new default random-number generator and Julia 1.7.3 fixed at least one security issue. Julia 1.8 added options for hiding source code when compiling Julia source code to executables. Julia 1.9 has added the ability to precompile packages to native machine code, done automatically; to improve precompilation of packages a new package PrecompileTools.jl was introduced, for use by package developers. Julia 1.10 was released on 25 December 2023 with new features such as parallel garbage collection. Julia 1.11 was released on 7 October 2024, and with it 1.10.5 became the next long-term support (LTS) version (i.e. those became the only two supported versions), since replaced by 1.10.10 released on 27 June, and 1.6 is no longer an LTS version. Julia 1.11 adds e.g. the new public keyword to signal safe public API (Julia users are advised to use such API, not internals, of Julia or packages, and package authors advised to use the keyword, generally indirectly, e.g. prefixed with the @compat macro, from Compat.jl, to also support older Julia versions, at least the LTS version). Julia 1.12 was released on 7 October 2025 (and 1.12.5 on 9 February 2026), and with it a JuliaC.jl package including the juliac compiler that works with it, for making rather small binary executables (much smaller than was possible before; through the use of new so-called trimming feature). Julia 1.10 LTS is an officially still-supported branch, but the 1.11 branch has also been maintained after 1.12 release, with 1.11.8 released and then 1.11.9 released on 8 February 2026. === JuliaCon === Since 2014, the Julia Community has hosted an annual Julia Conference focused on developers and users. The first JuliaCon took place in Chicago and kickstarted the annual occurrence of the conference. Since 2014, the conference has taken place across a number of locations including MIT and the University of Maryland, Baltimore. The event audience has grown from a few dozen people to over 28,900 unique attendees during JuliaCon 2020, which took place virtually. JuliaCon 2021 also took place virtually with keynote addresses from professors William Kahan, the primary architect of the IEEE 754 floating-point standard (which virtually all CPUs and languages, including Julia, use), Jan Vitek, Xiaoye Sherry Li, and Soumith Chintala, a co-creator of PyTorch. JuliaCon grew to 43,000 unique attendees and more than 300 presentations (still freely accessible, plus for older years). JuliaCon 2022 will also be virtual held between July 27 and July 29, 2022, for the first time in several languages, not just in English. === Sponsors === The Julia language became a NumFOCUS fiscally sponsored project in 2014 in an effort to ensure the project's long-term sustainability. Jeremy Kepner at MIT Lincoln Laboratory was the founding sponsor of the Julia project in its early days. In addition, funds from the Gordon and Betty Moore Foundation, the Alfred P. Sloan Foundation, Intel, and agencies such as NSF, DARPA, NIH, NASA, and FAA have been essential to the development of Julia. Mozilla, the maker of Firefox web browser, with its research grants for H1 2019, sponsored "a member of the official Julia team" for the project "Bringing Julia to the Browser", meaning to Firefox and other web browsers. The Julia language is also supported by individual donors on GitHub. === The Julia company === JuliaHub, Inc. was founded in 2015 as Julia Computing, Inc. by Viral B. Shah, Deepak Vinchhi, Alan Edelman, Jeff Bezanson, Stefan Karpinski and Keno Fischer. In June 2017, Julia Computing raised US$4.6 million in seed funding from General Catalyst and Founder Collective, the same month was "granted $910,000 by the Alfred P. Sloan Foundation to support open-source Julia development, including $160,000 to promote diversity in the Julia community", and in December 2019 the company got $1.1 million funding from the US government to "develop a neural component machine learning tool to reduce the total energy consumption of heating, ventilation, and air conditioning (HVAC) systems in buildings". In July 2021, Julia Computing announced they raised a $24 million Series A round led by Dorilton Ventures, which also owns Formula One team Williams Racing, that partnered with Julia Computing. Williams' Commercial Director said: "Investing in companies building best-in-class cloud technology is a strategic focus for Dorilton and Julia's versatile platform, with revolutionary capabilities in simulation and modelling, is hugely relevant to our business. We look forward to embedding Julia Computing in the world's most technologically advanced sport". In June 2023, JuliaHub received (again, now

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  • One-shot learning (computer vision)

    One-shot learning (computer vision)

    One-shot learning is an object categorization problem, found mostly in computer vision. Whereas most machine learning-based object categorization algorithms require training on hundreds or thousands of examples, one-shot learning aims to classify objects from one, or only a few, examples. The term few-shot learning is also used for these problems, especially when more than one example is needed. == Motivation == The ability to learn object categories from few examples, and at a rapid pace, has been demonstrated in humans. It is estimated that a child learns almost all of the 10 ~ 30 thousand object categories in the world by age six. This is due not only to the human mind's computational power, but also to its ability to synthesize and learn new object categories from existing information about different, previously learned categories. Given two examples from two object categories: one, an unknown object composed of familiar shapes, the second, an unknown, amorphous shape; it is much easier for humans to recognize the former than the latter, suggesting that humans make use of previously learned categories when learning new ones. The key motivation for solving one-shot learning is that systems, like humans, can use knowledge about object categories to classify new objects. == Background == As with most classification schemes, one-shot learning involves three main challenges: Representation: How should objects and categories be described? Learning: How can such descriptions be created? Recognition: How can a known object be filtered from enveloping clutter, irrespective of occlusion, viewpoint, and lighting? One-shot learning differs from single object recognition and standard category recognition algorithms in its emphasis on knowledge transfer, which makes use of previously learned categories. Model parameters: Reuses model parameters, based on the similarity between old and new categories. Categories are first learned on numerous training examples, then new categories are learned using transformations of model parameters from those initial categories or selecting relevant parameters for a classifier. Feature sharing: Shares parts or features of objects across categories. One algorithm extracts "diagnostic information" in patches from already learned categories by maximizing the patches' mutual information, and then applies these features to the learning of a new category. A dog category, for example, may be learned in one shot from previous knowledge of horse and cow categories, because dog objects may contain similar distinguishing patches. Contextual information: Appeals to global knowledge of the scene in which the object appears. Such global information can be used as frequency distributions in a conditional random field framework to recognize objects. Alternatively context can consider camera height and scene geometry. Algorithms of this type have two advantages. First, they learn object categories that are relatively dissimilar; and second, they perform well in ad hoc situations where an image has not been hand-cropped and aligned. == Theory == The Bayesian one-shot learning algorithm represents the foreground and background of images as parametrized by a mixture of constellation models. During the learning phase, the parameters of these models are learned using a conjugate density parameter posterior and variational Bayesian expectation–maximization (VBEM). In this stage the previously learned object categories inform the choice of model parameters via transfer by contextual information. For object recognition on new images, the posterior obtained during the learning phase is used in a Bayesian decision framework to estimate the ratio of p(object | test, train) to p(background clutter | test, train) where p is the probability of the outcome. === Bayesian framework === Given the task of finding a particular object in a query image, the overall objective of the Bayesian one-shot learning algorithm is to compare the probability that object is present vs the probability that only background clutter is present. If the former probability is higher, the algorithm reports the object's presence, otherwise the algorithm reports its absence. To compute these probabilities, the object class must be modeled from a set of (1 ~ 5) training images containing examples. To formalize these ideas, let I {\displaystyle I} be the query image, which contains either an example of the foreground category O f g {\displaystyle O_{fg}} or only background clutter of a generic background category O b g {\displaystyle O_{bg}} . Also let I t {\displaystyle I_{t}} be the set of training images used as the foreground category. The decision of whether I {\displaystyle I} contains an object from the foreground category, or only clutter from the background category is: R = p ( O f g | I , I t ) p ( O b g | I , I t ) = p ( I | I t , O f g ) p ( O f g ) p ( I | I t , O b g ) p ( O b g ) , {\displaystyle R={\frac {p(O_{fg}|I,I_{t})}{p(O_{bg}|I,I_{t})}}={\frac {p(I|I_{t},O_{fg})p(O_{fg})}{p(I|I_{t},O_{bg})p(O_{bg})}},} where the class posteriors p ( O f g | I , I t ) {\displaystyle p(O_{fg}|I,I_{t})} and p ( O b g | I , I t ) {\displaystyle p(O_{bg}|I,I_{t})} have been expanded by Bayes' theorem, yielding a ratio of likelihoods and a ratio of object category priors. We decide that the image I {\displaystyle I} contains an object from the foreground class if R {\displaystyle R} exceeds a certain threshold T {\displaystyle T} . We next introduce parametric models for the foreground and background categories with parameters θ {\displaystyle \theta } and θ b g {\displaystyle \theta _{bg}} respectively. This foreground parametric model is learned during the learning stage from I t {\displaystyle I_{t}} , as well as prior information of learned categories. The background model we assume to be uniform across images. Omitting the constant ratio of category priors, p ( O f g ) p ( O b g ) {\displaystyle {\frac {p(O_{fg})}{p(O_{bg})}}} , and parametrizing over θ {\displaystyle \theta } and θ b g {\displaystyle \theta _{bg}} yields R ∝ ∫ p ( I | θ , O f g ) p ( θ | I t , O f g ) d θ ∫ p ( I | θ b g , O b g ) p ( θ b g | I t , O b g ) d θ b g = ∫ p ( I | θ ) p ( θ | I t , O f g ) d θ ∫ p ( I | θ b g ) p ( θ b g | I t , O b g ) d θ b g {\displaystyle R\propto {\frac {\int {p(I|\theta ,O_{fg})p(\theta |I_{t},O_{fg})}d\theta }{\int {p(I|\theta _{bg},O_{bg})p(\theta _{bg}|I_{t},O_{bg})}d\theta _{bg}}}={\frac {\int {p(I|\theta )p(\theta |I_{t},O_{fg})}d\theta }{\int {p(I|\theta _{bg})p(\theta _{bg}|I_{t},O_{bg})}d\theta _{bg}}}} , having simplified p ( I | θ , O f g ) {\displaystyle p(I|\theta ,O_{fg})} and p ( I | θ , O b g ) {\displaystyle p(I|\theta ,O_{bg})} to p ( I | θ f g ) {\displaystyle p(I|\theta _{fg})} and p ( I | θ b g ) . {\displaystyle p(I|\theta _{bg}).} The posterior distribution of model parameters given the training images, p ( θ | I t , O f g ) {\displaystyle p(\theta |I_{t},O_{fg})} is estimated in the learning phase. In this estimation, one-shot learning differs sharply from more traditional Bayesian estimation models that approximate the integral as δ ( θ M L ) {\displaystyle \delta (\theta ^{ML})} . Instead, it uses a variational approach using prior information from previously learned categories. However, the traditional maximum likelihood estimation of the model parameters is used for the background model and the categories learned in advance through training. === Object category model === For each query image I {\displaystyle I} and training images I t {\displaystyle I_{t}} , a constellation model is used for representation. To obtain this model for a given image I {\displaystyle I} , first a set of N interesting regions is detected in the image using the Kadir–Brady saliency detector. Each region selected is represented by a location in the image, X i {\displaystyle X_{i}} and a description of its appearance, A i {\displaystyle A_{i}} . Letting X = ∑ i = 1 N X i , A = ∑ i = 1 N A i {\displaystyle X=\sum _{i=1}^{N}X_{i},A=\sum _{i=1}^{N}A_{i}} and X t {\displaystyle X_{t}} and A t {\displaystyle A_{t}} the analogous representations for training images, the expression for R becomes: R ∝ ∫ p ( X , A | θ , O f g ) p ( θ | X t , A t , O f g ) d θ ∫ p ( X , A | θ b g , O b g ) p ( θ b g | X t , A t , O b g ) d θ b g = ∫ p ( X , A | θ ) p ( θ | X t , A t , O f g ) d θ ∫ p ( X , A | θ b g ) p ( θ b g | X t , A t , O b g ) d θ b g {\displaystyle R\propto {\frac {\int {p(X,A|\theta ,O_{fg})p(\theta |X_{t},A_{t},O_{fg})}d\theta }{\int {p(X,A|\theta _{bg},O_{bg})p(\theta _{bg}|X_{t},A_{t},O_{bg})}d\theta _{bg}}}={\frac {\int {p(X,A|\theta )p(\theta |X_{t},A_{t},O_{fg})}d\theta }{\int {p(X,A|\theta _{bg})p(\theta _{bg}|X_{t},A_{t},O_{bg})}\,d\theta _{bg}}}} The likelihoods p ( X , A | θ ) {\displaystyle p(X,A|\theta )} and p ( X , A | θ b g ) {\displaystyle p(X,A|\theta _{bg})} are represented as mixtures of constellation models. A typical constellation model has

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  • Prescription monitoring program

    Prescription monitoring program

    In the United States, prescription monitoring programs (PMPs) or prescription drug monitoring programs (PDMPs) are state-run programs which collect and distribute data about the prescription and dispensation of federally controlled substances and, depending on state requirements, other potentially abusable prescription drugs. PMPs are meant to help prevent adverse drug-related events such as opioid overdoses, drug diversion, and substance abuse by decreasing the amount and/or frequency of opioid prescribing, and by identifying those patients who are obtaining prescriptions from multiple providers (i.e., "doctor shopping") or those physicians overprescribing opioids. Most US health care workers support the idea of PMPs, which intend to assist physicians, physician assistants, nurse practitioners, dentists and other prescribers, the pharmacists, chemists and support staff of dispensing establishments. The database, whose use is required by State law, typically requires prescribers and pharmacies dispensing controlled substances to register with their respective state PMPs and (for pharmacies and providers who dispense from their offices) to report the dispensation of such prescriptions to an electronic online database. The majority of PMPs are authorized to notify law enforcement agencies or licensing boards or physicians when a prescriber, or patients receiving prescriptions, exceed thresholds established by the state or prescription recipient exceeds thresholds established by the State. All states have implemented PDMPs, although evidence for the effectiveness of these programs is mixed. While prescription of opioids has decreased with PMP use, overdose deaths in many states have actually increased, with those states sharing data with neighboring jurisdictions or requiring reporting of more drugs experiencing highest increases in deaths. This may be because those declined opioid prescriptions turn to street drugs, whose potency and contaminants carry greater overdose risk. == History == Prescription drug monitoring programs, or PDMPs, are an example of one initiative proposed to alleviate effects of the opioid crisis. The programs are designed to restrict prescription drug abuse by limiting a patient's ability to obtain similar prescriptions from multiple providers (i.e. “doctor shopping”) and reducing diversion of controlled substances. This is meant to reduce risk of fatal overdose caused by high doses of opioids or interactions between opioids and benzodiazepenes, and to enable better decision making on the part of healthcare providers who may be unaware of a patient's prescription drug use, history or other prescriptions. PDMPs have been implemented in state legislations since 1939 in California, a time before electronic medical records, though implementation rose alongside increased awareness of overprescribing of opioids and overdose. A later New York state program was struck down by the U.S. Supreme Court in Whalen v. Roe. But, by 2019, 49 states, the District of Columbia, and Guam had enacted PDMP legislation. In 2021 Missouri, the last State to not use a PMP, adopted legislation to create one. PMPs are constantly being updated to increase speed of data collection, sharing of data across States, and ease of interpretation. This is being done by integrating PDMP reports with other health information technologies such as health information exchanges (HIE), electronic health record (EHR) systems, and/ or pharmacy dispensing software systems. One program that has been implemented in nine states is called the PDMP Electronic Health Records Integration and Interoperability Expansion, also known as PEHRIIE. Another software, marketed by Bamboo Health and integrated with PMPs in 43 states, uses an algorithm to track factors thought to increase risk of diversion, abuse or overdose, and assigns patients a three digit score based on presumed indicators of risk. While some studies have suggested that PDMP-HIT integration and sharing of interstate data brings benefits such as reduced opioid-related inpatient morbidity, others have found no or negative impact on mortality compared to states without PMP data sharing. Patient and media reports suggest need for testing and evaluation of algorithmic software used to score risk, with some patients reporting denial of prescriptions without c explanation or clarity of data. == Goals == Most health care workers support PMPs which intend to assist physicians, physician assistants, nurse practitioners, dentists and other prescribers, the pharmacists, chemists and support staff of dispensing establishments, as well as law-enforcement agencies. The collaboration supports the legitimate medical use of controlled substances while limiting their abuse and diversion. Pharmacies dispensing controlled substances and prescribers typically must register with their respective state PMPs and (for pharmacies and providers who dispense controlled substances from their offices) report the dispensation to an electronic online database. Some pharmacy software can submit these reports automatically to multiple states. == Usage == === List of programs by state === === Software systems === NarxCare is a prescription drug monitoring program (PDMP) run by Bamboo Health. Bamboo Health was formerly known as Appriss. It is widely used across the United States by pharmacies including Rite Aid as well as those at Walmart and Sam’s Club. The NarxCare software allows doctors to view data about a patient, combining data from the prescription registries of various U.S. states to make the registries interoperable nationally. It also uses machine learning to generate an "Overdose Risk Score" that potentially includes EMS and criminal justice data; these scores have been criticized by researchers and patient advocates for the lack of transparency in the process as well as the potential for disparate treatment of women and minority groups. Advertised as an "analytics tool and care management platform", the NarxCare software allows doctors to view data about a patient including how many pharmacies they have visited and the combinations of medication they are prescribed. It combines data from the prescription registries of various U.S. states, making the registries interoperable nationally. It additionally uses machine learning to generate various three-digit "risk scores" and an overall "Overdose Risk Score", collectively referred to as Narx Scores, in a process that potentially includes EMS and criminal justice data as well as court records. == Controversy == Many doctors and researchers support the idea of PDMPs as a tool in combatting the opioid epidemic. Opioid prescribing, opioid diversion and supply, opioid misuse, and opioid-related morbidity and mortality are common elements in data entered into PDMPs. Prescription Monitoring Programs are purported to offer economic benefits for the states who implement them by decreasing overall health care costs, lost productivity, and investigation times. However, there are many studies that conclude the impact of PDMPs is unclear. While use of PMPs has been accompanied by decrease in opioid prescribing, few analyses consider corresponding use of street opioids, extramedical use, or diversion, which might provide a more holistic method for evaluation of PMP intent and efficacy. Evidence for PDMP impact on fatal overdoses is decidedly mixed, with multiple studies finding increased overdose rates in some states, decreases in others, or no clear impact. Interestingly, an increase in heroin overdoses after PDMP implementation has been commonly reported, presumably as denial of prescription opioids sends patients in search of street drugs. Narx Scores have been criticized by researchers and patient advocates for the lack of transparency in the generation process as well as the potential for disparate treatment of women and minority groups. Writing in Duke Law Journal, Jennifer Oliva stated that "black-box algorithms" are used to generate the scores.

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  • The Drivers Cooperative

    The Drivers Cooperative

    The Drivers Cooperative or Co-Op Ride is an American ridesharing company and mobile app that is a workers cooperative, owned collectively by the drivers. The cooperative launched in May 2021 in New York City, with the first 2,500 drivers issued their ownership certificates in a media event. The cooperative was co-founded by Grenadan immigrant and for hire vehicle driver Ken Lewis, labor organizer Erik Forman, and former Uber executive Alissa Orlando. Mohammad Hossen is the first member of the drivers' advisory board, which they plan to expand democratically as more drivers are onboarded. Other staff include software and industry veterans and in addition to co-founder Lewis, there are other drivers in management roles such as ex-driver and organizer David Alexis. The Co-Op Ride app is on the iOS and Android platforms and is built on Google Maps, Stripe, and Waze. By July, the app had been downloaded by 30,000 users and the number of drivers increased to 3,400, and by August there were 40,000 users. The cooperative is owned by the drivers themselves, and takes 15% from each ride for business overhead costs, as opposed to the 25% to 40% ride hail apps like Uber or Lyft take per ride. While being ultimately owned by the driver members, not by investors, the cooperative began with seed money from the Minnesota-based Community Development Financial Institution Shared Capital Cooperative, the local Lower East Side People's Federal Credit Union, and welcomed individual donations via crowdfunding in the form of revenue sharing debt on Wefunder. Each driver is a member of the cooperative and owns one share of the company and one vote in business and leadership decisions. In addition to a larger percentage of the fees per ride driven, each driver as a part-owner will also receive a share of the company's profits after loans and other expenses are paid, in the form of weighted dividends. The drivers use their own cars. The cooperative vets its owner-members further than what is already performed by the New York City Taxi and Limousine Commission (TLC), and gives a fixed price when a car is ordered and does not engage in surge pricing. The TLC imposed a minimum payrate for mobile app ridesharing companies operating in New York city in 2018. In 2021 that is $1.26 per mile which Uber and Lyft do not pay above; the cooperative pays a minimum mileage of $1.64. The cooperative intends to be able to set aside 10% of profits to community foundations and other non-profits and community organizations. The cooperative has engaged in advocacy around a policy agenda voted on by its members. Legislation to achieve this policy goal was introduced by State Senator Julia Salazar and Assemblymember Jessica González-Rojas, with the support of a coalition led by The Drivers Cooperative, United Auto Workers Region 9 and 9A, Sunrise Movement, New York Lawyers for the Public Interest, and New York Communities for Change.

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  • Low-rank approximation

    Low-rank approximation

    In mathematics, low-rank approximation refers to the process of approximating a given matrix by a matrix of lower rank. More precisely, it is a minimization problem, in which the cost function measures the fit between a given matrix (the data) and an approximating matrix (the optimization variable), subject to a constraint that the approximating matrix has reduced rank. The problem is used for mathematical modeling and data compression. The rank constraint is related to a constraint on the complexity of a model that fits the data. In applications, often there are other constraints on the approximating matrix apart from the rank constraint, e.g., non-negativity and Hankel structure. Low-rank approximation is closely related to numerous other techniques, including principal component analysis, factor analysis, total least squares, latent semantic analysis, orthogonal regression, and dynamic mode decomposition. == Definition == Given structure specification S : R n p → R m × n {\displaystyle {\mathcal {S}}:\mathbb {R} ^{n_{p}}\to \mathbb {R} ^{m\times n}} , vector of structure parameters p ∈ R n p {\displaystyle p\in \mathbb {R} ^{n_{p}}} , norm ‖ ⋅ ‖ {\displaystyle \|\cdot \|} , and desired rank r {\displaystyle r} , minimize over p ^ ‖ p − p ^ ‖ subject to rank ⁡ ( S ( p ^ ) ) ≤ r . {\displaystyle {\text{minimize}}\quad {\text{over }}{\widehat {p}}\quad \|p-{\widehat {p}}\|\quad {\text{subject to}}\quad \operatorname {rank} {\big (}{\mathcal {S}}({\widehat {p}}){\big )}\leq r.} == Applications == Linear system identification, in which case the approximating matrix is Hankel structured. Machine learning, in which case the approximating matrix is nonlinearly structured. Recommender systems, in which cases the data matrix has missing values and the approximation is categorical. Distance matrix completion, in which case there is a positive definiteness constraint. Natural language processing, in which case the approximation is nonnegative. Computer algebra, in which case the approximation is Sylvester structured. Matrix product states, in which case the approximation is usually rescaled to have fixed Frobenius norm. == Basic low-rank approximation problem == The unstructured problem with fit measured by the Frobenius norm, i.e., minimize over D ^ ‖ D − D ^ ‖ F subject to rank ⁡ ( D ^ ) ≤ r {\displaystyle {\text{minimize}}\quad {\text{over }}{\widehat {D}}\quad \|D-{\widehat {D}}\|_{\text{F}}\quad {\text{subject to}}\quad \operatorname {rank} {\big (}{\widehat {D}}{\big )}\leq r} has an analytic solution in terms of the singular value decomposition of the data matrix. The result is referred to as the matrix approximation lemma or Eckart–Young–Mirsky theorem. This problem was originally solved by Erhard Schmidt in the infinite dimensional context of integral operators (although his methods easily generalize to arbitrary compact operators on Hilbert spaces) and later rediscovered by C. Eckart and G. Young. L. Mirsky generalized the result to arbitrary unitarily invariant norms. Let D = U Σ V ⊤ ∈ R m × n , m ≥ n {\displaystyle D=U\Sigma V^{\top }\in \mathbb {R} ^{m\times n},\quad m\geq n} be the singular value decomposition of D {\displaystyle D} , where Σ =: diag ⁡ ( σ 1 , … , σ r ) {\displaystyle \Sigma =:\operatorname {diag} (\sigma _{1},\ldots ,\sigma _{r})} , where r ≤ min { m , n } = n {\displaystyle r\leq \min\{m,n\}=n} , is the m × n {\displaystyle m\times n} rectangular diagonal matrix with r {\displaystyle r} non-zero singular values σ 1 ≥ … ≥ σ r > σ r + 1 = … = σ n = 0 {\displaystyle \sigma _{1}\geq \ldots \geq \sigma _{r}>\sigma _{r+1}=\ldots =\sigma _{n}=0} . For a given k ∈ { 1 , … , r } {\displaystyle k\in \{1,\dots ,r\}} , partition U {\displaystyle U} , Σ {\displaystyle \Sigma } , and V {\displaystyle V} as follows: U =: [ U 1 U 2 ] , Σ =: [ Σ 1 0 0 Σ 2 ] , and V =: [ V 1 V 2 ] , {\displaystyle U=:{\begin{bmatrix}U_{1}&U_{2}\end{bmatrix}},\quad \Sigma =:{\begin{bmatrix}\Sigma _{1}&0\\0&\Sigma _{2}\end{bmatrix}},\quad {\text{and}}\quad V=:{\begin{bmatrix}V_{1}&V_{2}\end{bmatrix}},} where U 1 {\displaystyle U_{1}} is m × k {\displaystyle m\times k} , Σ 1 {\displaystyle \Sigma _{1}} is k × k {\displaystyle k\times k} , and V 1 {\displaystyle V_{1}} is n × k {\displaystyle n\times k} . Then the rank k {\displaystyle k} matrix D ^ ∗ := U 1 Σ 1 V 1 ⊤ , {\displaystyle {\widehat {D}}^{}:=U_{1}\Sigma _{1}V_{1}^{\top },} obtained from the truncated singular value decomposition is such that ‖ D − D ^ ∗ ‖ F = min rank ⁡ ( D ^ ) ≤ k ‖ D − D ^ ‖ F = σ k + 1 2 + ⋯ + σ r 2 . {\displaystyle \|D-{\widehat {D}}^{}\|_{\text{F}}=\min _{\operatorname {rank} ({\widehat {D}})\leq k}\|D-{\widehat {D}}\|_{\text{F}}={\sqrt {\sigma _{k+1}^{2}+\cdots +\sigma _{r}^{2}}}.} The minimizer D ^ ∗ {\displaystyle {\widehat {D}}^{}} is unique if and only if σ k > σ k + 1 {\displaystyle \sigma _{k}>\sigma _{k+1}} . == Proof of Eckart–Young–Mirsky theorem (for spectral norm) == Let A ∈ R m × n {\displaystyle A\in \mathbb {R} ^{m\times n}} be a real (possibly rectangular) matrix with m ≤ n {\displaystyle m\leq n} . Suppose that A = U Σ V ⊤ {\displaystyle A=U\Sigma V^{\top }} is the singular value decomposition of A {\displaystyle A} . Recall that U {\displaystyle U} and V {\displaystyle V} are orthogonal matrices, and Σ {\displaystyle \Sigma } is an m × n {\displaystyle m\times n} diagonal matrix with entries ( σ 1 , σ 2 , ⋯ , σ m ) {\displaystyle (\sigma _{1},\sigma _{2},\cdots ,\sigma _{m})} such that σ 1 ≥ σ 2 ≥ ⋯ ≥ σ m ≥ 0 {\displaystyle \sigma _{1}\geq \sigma _{2}\geq \cdots \geq \sigma _{m}\geq 0} . We claim that the best rank- k {\displaystyle k} approximation to A {\displaystyle A} in the spectral norm, denoted by ‖ ⋅ ‖ 2 {\displaystyle \|\cdot \|_{2}} , is given by A k := ∑ i = 1 k σ i u i v i ⊤ {\displaystyle A_{k}:=\sum _{i=1}^{k}\sigma _{i}u_{i}v_{i}^{\top }} where u i {\displaystyle u_{i}} and v i {\displaystyle v_{i}} denote the i {\displaystyle i} th column of U {\displaystyle U} and V {\displaystyle V} , respectively. First, note that we have ‖ A − A k ‖ 2 = ‖ ∑ i = 1 n σ i u i v i ⊤ − ∑ i = 1 k σ i u i v i ⊤ ‖ 2 = ‖ ∑ i = k + 1 n σ i u i v i ⊤ ‖ 2 = σ k + 1 {\displaystyle \|A-A_{k}\|_{2}=\left\|\sum _{i=1}^{\color {red}{n}}\sigma _{i}u_{i}v_{i}^{\top }-\sum _{i=1}^{\color {red}{k}}\sigma _{i}u_{i}v_{i}^{\top }\right\|_{2}=\left\|\sum _{i=\color {red}{k+1}}^{n}\sigma _{i}u_{i}v_{i}^{\top }\right\|_{2}=\sigma _{k+1}} Therefore, we need to show that if B k = X Y ⊤ {\displaystyle B_{k}=XY^{\top }} where X {\displaystyle X} and Y {\displaystyle Y} have k {\displaystyle k} columns then ‖ A − A k ‖ 2 = σ k + 1 ≤ ‖ A − B k ‖ 2 {\displaystyle \|A-A_{k}\|_{2}=\sigma _{k+1}\leq \|A-B_{k}\|_{2}} . Since Y {\displaystyle Y} has k {\displaystyle k} columns, then there must be a nontrivial linear combination of the first k + 1 {\displaystyle k+1} columns of V {\displaystyle V} , i.e., w = γ 1 v 1 + ⋯ + γ k + 1 v k + 1 , {\displaystyle w=\gamma _{1}v_{1}+\cdots +\gamma _{k+1}v_{k+1},} such that Y ⊤ w = 0 {\displaystyle Y^{\top }w=0} . Without loss of generality, we can scale w {\displaystyle w} so that ‖ w ‖ 2 = 1 {\displaystyle \|w\|_{2}=1} or (equivalently) γ 1 2 + ⋯ + γ k + 1 2 = 1 {\displaystyle \gamma _{1}^{2}+\cdots +\gamma _{k+1}^{2}=1} . Therefore, ‖ A − B k ‖ 2 2 ≥ ‖ ( A − B k ) w ‖ 2 2 = ‖ A w ‖ 2 2 = γ 1 2 σ 1 2 + ⋯ + γ k + 1 2 σ k + 1 2 ≥ σ k + 1 2 . {\displaystyle \|A-B_{k}\|_{2}^{2}\geq \|(A-B_{k})w\|_{2}^{2}=\|Aw\|_{2}^{2}=\gamma _{1}^{2}\sigma _{1}^{2}+\cdots +\gamma _{k+1}^{2}\sigma _{k+1}^{2}\geq \sigma _{k+1}^{2}.} The result follows by taking the square root of both sides of the above inequality. == Proof of Eckart–Young–Mirsky theorem (for Frobenius norm) == Let A ∈ R m × n {\displaystyle A\in \mathbb {R} ^{m\times n}} be a real (possibly rectangular) matrix with m ≤ n {\displaystyle m\leq n} . Suppose that A = U Σ V ⊤ {\displaystyle A=U\Sigma V^{\top }} is the singular value decomposition of A {\displaystyle A} . We claim that the best rank k {\displaystyle k} approximation to A {\displaystyle A} in the Frobenius norm, denoted by ‖ ⋅ ‖ F {\displaystyle \|\cdot \|_{F}} , is given by A k = ∑ i = 1 k σ i u i v i ⊤ {\displaystyle A_{k}=\sum _{i=1}^{k}\sigma _{i}u_{i}v_{i}^{\top }} where u i {\displaystyle u_{i}} and v i {\displaystyle v_{i}} denote the i {\displaystyle i} th column of U {\displaystyle U} and V {\displaystyle V} , respectively. First, note that we have ‖ A − A k ‖ F 2 = ‖ ∑ i = k + 1 n σ i u i v i ⊤ ‖ F 2 = ∑ i = k + 1 n σ i 2 {\displaystyle \|A-A_{k}\|_{F}^{2}=\left\|\sum _{i=k+1}^{n}\sigma _{i}u_{i}v_{i}^{\top }\right\|_{F}^{2}=\sum _{i=k+1}^{n}\sigma _{i}^{2}} Therefore, we need to show that if B k = X Y ⊤ {\displaystyle B_{k}=XY^{\top }} where X {\displaystyle X} and Y {\displaystyle Y} have k {\displaystyle k} columns then ‖ A − A k ‖ F 2 = ∑ i = k + 1 n σ i 2 ≤ ‖ A − B k ‖ F 2 . {\displaystyle \|A-A_{k}\|_{F}^{2}=\sum _{i=k+1}^{n}\sigma _{i}^{2}\leq \|A-B_{k}\|_{F}^{2}.} By the triangle inequality with the spectral norm

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  • Prefrontal cortex basal ganglia working memory

    Prefrontal cortex basal ganglia working memory

    Prefrontal cortex basal ganglia working memory (PBWM) is an algorithm that models working memory in the prefrontal cortex and the basal ganglia. It can be compared to long short-term memory (LSTM) in functionality, but is more biologically explainable. It uses the primary value learned value model to train prefrontal cortex working-memory updating system, based on the biology of the prefrontal cortex and basal ganglia. It is used as part of the Leabra framework and was implemented in Emergent in 2019. == Abstract == The prefrontal cortex has long been thought to subserve both working memory (the holding of information online for processing) and "executive" functions (deciding how to manipulate working memory and perform processing). Although many computational models of working memory have been developed, the mechanistic basis of executive function remains elusive. PBWM is a computational model of the prefrontal cortex to control both itself and other brain areas in a strategic, task-appropriate manner. These learning mechanisms are based on subcortical structures in the midbrain, basal ganglia and amygdala, which together form an actor/critic architecture. The critic system learns which prefrontal representations are task-relevant and trains the actor, which in turn provides a dynamic gating mechanism for controlling working memory updating. Computationally, the learning mechanism is designed to simultaneously solve the temporal and structural credit assignment problems. The model's performance compares favorably with standard backpropagation-based temporal learning mechanisms on the challenging 1-2-AX working memory task, and other benchmark working memory tasks. == Model == First, there are multiple separate stripes (groups of units) in the prefrontal cortex and striatum layers. Each stripe can be independently updated, such that this system can remember several different things at the same time, each with a different "updating policy" of when memories are updated and maintained. The active maintenance of the memory is in prefrontal cortex (PFC), and the updating signals (and updating policy more generally) come from the striatum units (a subset of basal ganglia units). PVLV provides reinforcement learning signals to train up the dynamic gating system in the basal ganglia. === Sensory input and motor output === The sensory input is connected to the posterior cortex which is connected to the motor output. The sensory input is also linked to the PVLV system. === Posterior cortex === The posterior cortex form the hidden layers of the input/output mapping. The PFC is connected with the posterior cortex to contextualize this input/output mapping. === PFC === The PFC (for output gating) has a localist one-to-one representation of the input units for every stripe. Thus, you can look at these PFC representations and see directly what the network is maintaining. The PFC maintains the working memory needed to perform the task. === Striatum === This is the dynamic gating system representing the striatum units of the basal ganglia. Every even-index unit within a stripe represents "Go", while the odd-index units represent "NoGo." The Go units cause updating of the PFC, while the NoGo units cause the PFC to maintain its existing memory representation. There are groups of units for every stripe. In the PBWM model in Emergent, the matrices represent the striatum. === PVLV === All of these layers are part of PVLV system. The PVLV system controls the dopaminergic modulation of the basal ganglia (BG). Thus, BG/PVLV form an actor-critic architecture where the PVLV system learns when to update. ==== SNrThal ==== SNrThal represents the substantia nigra pars reticulata (SNr) and the associated area of the thalamus, which produce a competition among the Go/NoGo units within a given stripe and mediates competition using k-winners-take-all dynamics. If there is more overall Go activity in a given stripe, then the associated SNrThal unit gets activated, and it drives updating in PFC. For every stripe, there is one unit in SNrThal. ==== VTA and SNc ==== Ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) are part of the dopamine layer. This layer models midbrain dopamine neurons. They control the dopaminergic modulation of the basal ganglia.

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