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  Line integral convolution

  In scientific visualization, line integral convolution (LIC) is a method to visualize a vector field (such as fluid motion) at high spatial resolutions. The LIC technique was first proposed by Brian Cabral and Leith Casey Leedom in 1993. In LIC, discrete numerical line integration is performed along the field lines (curves) of the vector field on a uniform grid. The integral operation is a convolution of a filter kernel and an input texture, often white noise. In signal processing, this process is known as a discrete convolution. == Overview == Traditional visualizations of vector fields use small arrows or lines to represent vector direction and magnitude. This method has a low spatial resolution, which limits the density of presentable data and risks obscuring characteristic features in the data. More sophisticated methods, such as streamlines and particle tracing techniques, can be more revealing but are highly dependent on proper seed points. Texture-based methods, like LIC, avoid these problems since they depict the entire vector field at point-like (pixel) resolution. Compared to other integration-based techniques that compute field lines of the input vector field, LIC has the advantage that all structural features of the vector field are displayed, without the need to adapt the start and end points of field lines to the specific vector field. In other words, it shows the topology of the vector field. In user testing, LIC was found to be particularly good for identifying critical points. == Algorithm == === Informal description === LIC causes output values to be strongly correlated along the field lines, but uncorrelated in orthogonal directions. As a result, the field lines contrast each other and stand out visually from the background. Intuitively, the process can be understood with the following example: the flow of a vector field can be visualized by overlaying a fixed, random pattern of dark and light paint. As the flow passes by the paint, the fluid picks up some of the paint's color, averaging it with the color it has already acquired. The result is a randomly striped, smeared texture where points along the same streamline tend to have a similar color. Other physical examples include: whorl patterns of paint, oil, or foam on a river visualisation of magnetic field lines using randomly distributed iron filings fine sand being blown by strong wind === Formal mathematical description === Although the input vector field and the result image are discretized, it pays to look at it from a continuous viewpoint. Let v {\displaystyle \mathbf {v} } be the vector field given in some domain Ω {\displaystyle \Omega } . Although the input vector field is typically discretized, we regard the field v {\displaystyle \mathbf {v} } as defined in every point of Ω {\displaystyle \Omega } , i.e. we assume an interpolation. Streamlines, or more generally field lines, are tangent to the vector field in each point. They end either at the boundary of Ω {\displaystyle \Omega } or at critical points where v = 0 {\displaystyle \mathbf {v} =\mathbf {0} } . For the sake of simplicity, critical points and boundaries are ignored in the following. A field line σ {\displaystyle {\boldsymbol {\sigma }}} , parametrized by arc length s {\displaystyle s} , is defined as d σ ( s ) d s = v ( σ ( s ) ) | v ( σ ( s ) ) | . {\displaystyle {\frac {d{\boldsymbol {\sigma }}(s)}{ds}}={\frac {\mathbf {v} ({\boldsymbol {\sigma }}(s))}{|\mathbf {v} ({\boldsymbol {\sigma }}(s))|}}.} Let σ r ( s ) {\displaystyle {\boldsymbol {\sigma }}_{\mathbf {r} }(s)} be the field line that passes through the point r {\displaystyle \mathbf {r} } for s = 0 {\displaystyle s=0} . Then the image gray value at r {\displaystyle \mathbf {r} } is set to D ( r ) = ∫ − L / 2 L / 2 k ( s ) N ( σ r ( s ) ) d s {\displaystyle D(\mathbf {r} )=\int _{-L/2}^{L/2}k(s)N({\boldsymbol {\sigma }}_{\mathbf {r} }(s))ds} where k ( s ) {\displaystyle k(s)} is the convolution kernel, N ( r ) {\displaystyle N(\mathbf {r} )} is the noise image, and L {\displaystyle L} is the length of field line segment that is followed. D ( r ) {\displaystyle D(\mathbf {r} )} has to be computed for each pixel in the LIC image. If carried out naively, this is quite expensive. First, the field lines have to be computed using a numerical method for solving ordinary differential equations, like a Runge–Kutta method, and then for each pixel the convolution along a field line segment has to be calculated. The final image will normally be colored in some way. Typically, some scalar field in Ω {\displaystyle \Omega } (like the vector length) is used to determine the hue, while the grayscale LIC output determines the brightness. Different choices of convolution kernels and random noise produce different textures; for example, pink noise produces a cloudy pattern where areas of higher flow stand out as smearing, suitable for weather visualization. Further refinements in the convolution can improve the quality of the image. === Programming description === Algorithmically, LIC takes a vector field and noise texture as input, and outputs a texture. The process starts by generating in the domain of the vector field a random gray level image at the desired output resolution. Then, for every pixel in this image, the forward and backward streamline of a fixed arc length is calculated. The value assigned to the current pixel is computed by a convolution of a suitable convolution kernel with the gray levels of all the noise pixels lying on a segment of this streamline. This creates a gray level LIC image. == Versions == === Basic === Basic LIC images are grayscale images, without color and animation. While such LIC images convey the direction of the field vectors, they do not indicate orientation; for stationary fields, this can be remedied by animation. Basic LIC images do not show the length of the vectors (or the strength of the field). === Color === The length of the vectors (or the strength of the field) is usually coded in color; alternatively, animation can be used. === Animation === LIC images can be animated by using a kernel that changes over time. Samples at a constant time from the streamline would still be used, but instead of averaging all pixels in a streamline with a static kernel, a ripple-like kernel constructed from a periodic function multiplied by a Hann function acting as a window (in order to prevent artifacts) is used. The periodic function is then shifted along the period to create an animation. === Fast LIC (FLIC) === The computation can be significantly accelerated by re-using parts of already computed field lines, specializing to a box function as convolution kernel k ( s ) {\displaystyle k(s)} and avoiding redundant computations during convolution. The resulting fast LIC method can be generalized to convolution kernels that are arbitrary polynomials. === Oriented Line Integral Convolution (OLIC) === Because LIC does not encode flow orientation, it cannot distinguish between streamlines of equal direction but opposite orientation. Oriented Line Integral Convolution (OLIC) solves this issue by using a ramp-like asymmetric kernel and a low-density noise texture. The kernel asymmetrically modulates the intensity along the streamline, producing a trace that encodes orientation; the low-density of the noise texture prevents smeared traces from overlapping, aiding readability. Fast Rendering of Oriented Line Integral Convolution (FROLIC) is a variation that approximates OLIC by rendering each trace in discrete steps instead of as a continuous smear. === Unsteady Flow LIC (UFLIC) === For time-dependent vector fields (unsteady flow), a variant called Unsteady Flow LIC has been designed that maintains the coherence of the flow animation. An interactive GPU-based implementation of UFLIC has been presented. === Parallel === Since the computation of an LIC image is expensive but inherently parallel, the process has been parallelized and, with availability of GPU-based implementations, interactive on PCs. === Multidimensional === Note that the domain Ω {\displaystyle \Omega } does not have to be a 2D domain: the method is applicable to higher dimensional domains using multidimensional noise fields. However, the visualization of the higher-dimensional LIC texture is problematic; one way is to use interactive exploration with 2D slices that are manually positioned and rotated. The domain Ω {\displaystyle \Omega } does not have to be flat either; the LIC texture can be computed also for arbitrarily shaped 2D surfaces in 3D space. == Applications == This technique has been applied to a wide range of problems since it first was published in 1993, both scientific and creative, including: Representing vector fields: visualization of steady (time-independent) flows (streamlines) visual exploration of 2D autonomous dynamical systems wind mapping water flow mapping Artistic effects for image generation and stylization: pencil drawing (auto

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  Policy gradient method

  Policy gradient methods are a class of reinforcement learning algorithms and a sub-class of policy optimization methods. Unlike value-based methods which learn a value function to derive a policy, policy optimization methods directly learn a policy function π {\displaystyle \pi } that selects actions without consulting a value function. For policy gradient to apply, the policy function π θ {\displaystyle \pi _{\theta }} is parameterized by a differentiable parameter θ {\displaystyle \theta } . == Overview == In policy-based RL, the actor is a parameterized policy function π θ {\displaystyle \pi _{\theta }} , where θ {\displaystyle \theta } are the parameters of the actor. The actor takes as argument the state of the environment s {\displaystyle s} and produces a probability distribution π θ ( ⋅ ∣ s ) {\displaystyle \pi _{\theta }(\cdot \mid s)} . If the action space is discrete, then ∑ a π θ ( a ∣ s ) = 1 {\displaystyle \sum _{a}\pi _{\theta }(a\mid s)=1} . If the action space is continuous, then ∫ a π θ ( a ∣ s ) d a = 1 {\displaystyle \int _{a}\pi _{\theta }(a\mid s)\mathrm {d} a=1} . The goal of policy optimization is to find some θ {\displaystyle \theta } that maximizes the expected episodic reward J ( θ ) {\displaystyle J(\theta )} : J ( θ ) = E π θ [ ∑ t = 0 T γ t R t | S 0 = s 0 ] {\displaystyle J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\gamma ^{t}R_{t}{\Big |}S_{0}=s_{0}\right]} where γ {\displaystyle \gamma } is the discount factor, R t {\displaystyle R_{t}} is the reward at step t {\displaystyle t} , s 0 {\displaystyle s_{0}} is the starting state, and T {\displaystyle T} is the time-horizon (which can be infinite). The policy gradient is defined as ∇ θ J ( θ ) {\displaystyle \nabla _{\theta }J(\theta )} . Different policy gradient methods stochastically estimate the policy gradient in different ways. The goal of any policy gradient method is to iteratively maximize J ( θ ) {\displaystyle J(\theta )} by gradient ascent. Since the key part of any policy gradient method is the stochastic estimation of the policy gradient, they are also studied under the title of "Monte Carlo gradient estimation". == REINFORCE == === Policy gradient === The REINFORCE algorithm, introduced by Ronald J. Williams in 1992, was the first policy gradient method. It is based on the identity for the policy gradient ∇ θ J ( θ ) = E π θ [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t ∣ S t ) ∑ t = 0 T ( γ t R t ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t}\mid S_{t})\;\sum _{t=0}^{T}(\gamma ^{t}R_{t}){\Big |}S_{0}=s_{0}\right]} which can be improved via the "causality trick" ∇ θ J ( θ ) = E π θ [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t ∣ S t ) ∑ τ = t T ( γ τ R τ ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t}\mid S_{t})\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau }){\Big |}S_{0}=s_{0}\right]} Thus, we have an unbiased estimator of the policy gradient: ∇ θ J ( θ ) ≈ 1 N ∑ n = 1 N [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t , n ∣ S t , n ) ∑ τ = t T ( γ τ − t R τ , n ) ] {\displaystyle \nabla _{\theta }J(\theta )\approx {\frac {1}{N}}\sum _{n=1}^{N}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t,n}\mid S_{t,n})\sum _{\tau =t}^{T}(\gamma ^{\tau -t}R_{\tau ,n})\right]} where the index n {\displaystyle n} ranges over N {\displaystyle N} rollout trajectories using the policy π θ {\displaystyle \pi _{\theta }} . The score function ∇ θ ln ⁡ π θ ( A t ∣ S t ) {\displaystyle \nabla _{\theta }\ln \pi _{\theta }(A_{t}\mid S_{t})} can be interpreted as the direction in the parameter space that increases the probability of taking action A t {\displaystyle A_{t}} in state S t {\displaystyle S_{t}} . The policy gradient, then, is a weighted average of all possible directions to increase the probability of taking any action in any state, but weighted by reward signals, so that if taking a certain action in a certain state is associated with high reward, then that direction would be highly reinforced, and vice versa. === Algorithm === The REINFORCE algorithm is a loop: Rollout N {\displaystyle N} trajectories in the environment, using π θ t {\displaystyle \pi _{\theta _{t}}} as the policy function. Compute the policy gradient estimation: g i ← 1 N ∑ n = 1 N [ ∑ t = 0 T ∇ θ t ln ⁡ π θ ( A t , n ∣ S t , n ) ∑ τ = t T ( γ τ R τ , n ) ] {\displaystyle g_{i}\leftarrow {\frac {1}{N}}\sum _{n=1}^{N}\left[\sum _{t=0}^{T}\nabla _{\theta _{t}}\ln \pi _{\theta }(A_{t,n}\mid S_{t,n})\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau ,n})\right]} Update the policy by gradient ascent: θ i + 1 ← θ i + α i g i {\displaystyle \theta _{i+1}\leftarrow \theta _{i}+\alpha _{i}g_{i}} Here, α i {\displaystyle \alpha _{i}} is the learning rate at update step i {\displaystyle i} . == Variance reduction == REINFORCE is an on-policy algorithm, meaning that the trajectories used for the update must be sampled from the current policy π θ {\displaystyle \pi _{\theta }} . This can lead to high variance in the updates, as the returns R ( τ ) {\displaystyle R(\tau )} can vary significantly between trajectories. Many variants of REINFORCE have been introduced, under the title of variance reduction. === REINFORCE with baseline === A common way for reducing variance is the REINFORCE with baseline algorithm, based on the following identity: ∇ θ J ( θ ) = E π θ [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t | S t ) ( ∑ τ = t T ( γ τ R τ ) − b ( S t ) ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t}|S_{t})\left(\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau })-b(S_{t})\right){\Big |}S_{0}=s_{0}\right]} for any function b : States → R {\displaystyle b:{\text{States}}\to \mathbb {R} } . This can be proven by applying the previous lemma. The algorithm uses the modified gradient estimator g i ← 1 N ∑ n = 1 N [ ∑ t = 0 T ∇ θ t ln ⁡ π θ ( A t , n | S t , n ) ( ∑ τ = t T ( γ τ R τ , n ) − b i ( S t , n ) ) ] {\displaystyle g_{i}\leftarrow {\frac {1}{N}}\sum _{n=1}^{N}\left[\sum _{t=0}^{T}\nabla _{\theta _{t}}\ln \pi _{\theta }(A_{t,n}|S_{t,n})\left(\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau ,n})-b_{i}(S_{t,n})\right)\right]} and the original REINFORCE algorithm is the special case where b i ≡ 0 {\displaystyle b_{i}\equiv 0} . === Actor-critic methods === If b i {\textstyle b_{i}} is chosen well, such that b i ( S t ) ≈ ∑ τ = t T ( γ τ R τ ) = γ t V π θ i ( S t ) {\textstyle b_{i}(S_{t})\approx \sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau })=\gamma ^{t}V^{\pi _{\theta _{i}}}(S_{t})} , this could significantly decrease variance in the gradient estimation. That is, the baseline should be as close to the value function V π θ i ( S t ) {\displaystyle V^{\pi _{\theta _{i}}}(S_{t})} as possible, approaching the ideal of: ∇ θ J ( θ ) = E π θ [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t | S t ) ( ∑ τ = t T ( γ τ R τ ) − γ t V π θ ( S t ) ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t}|S_{t})\left(\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau })-\gamma ^{t}V^{\pi _{\theta }}(S_{t})\right){\Big |}S_{0}=s_{0}\right]} Note that, as the policy π θ t {\displaystyle \pi _{\theta _{t}}} updates, the value function V π θ i ( S t ) {\displaystyle V^{\pi _{\theta _{i}}}(S_{t})} updates as well, so the baseline should also be updated. One common approach is to train a separate function that estimates the value function, and use that as the baseline. This is one of the actor-critic methods, where the policy function is the actor and the value function is the critic. The Q-function Q π {\displaystyle Q^{\pi }} can also be used as the critic, since ∇ θ J ( θ ) = E π θ [ ∑ 0 ≤ t ≤ T γ t ∇ θ ln ⁡ π θ ( A t | S t ) ⋅ Q π θ ( S t , A t ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=E_{\pi _{\theta }}\left[\sum _{0\leq t\leq T}\gamma ^{t}\nabla _{\theta }\ln \pi _{\theta }(A_{t}|S_{t})\cdot Q^{\pi _{\theta }}(S_{t},A_{t}){\Big |}S_{0}=s_{0}\right]} by a similar argument using the tower law. Subtracting the value function as a baseline, we find that the advantage function A π ( S , A ) = Q π ( S , A ) − V π ( S ) {\displaystyle A^{\pi }(S,A)=Q^{\pi }(S,A)-V^{\pi }(S)} can be used as the critic as well: ∇ θ J ( θ ) = E π θ [ ∑ 0 ≤ t ≤ T γ t ∇ θ ln ⁡ π θ ( A t | S t ) ⋅ A π θ ( S t , A t ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=E_{\pi _{\theta }}\left[\sum _{0\leq t\leq T}\gamma ^{t}\nabla _{\theta }\ln \pi _{\theta }(A_{t}|S_{t})\cdot A^{\pi _{\theta }}(S_{t},A_{t}){\Big |}S_{0}=s_{0}\right]} In summary, there are many unbiased estimators for ∇ θ J θ {\textstyle \nabla _{\theta }J_{\theta }} , all in the form of: ∇ θ J ( θ ) = E π θ [ ∑ 0 ≤ t ≤ T ∇ θ ln ⁡ π θ ( A t | S t ) ⋅ Ψ t | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=E_{\pi _{\theta }}\left[\su

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  Targeted maximum likelihood estimation

  Targeted Maximum Likelihood Estimation (TMLE) (also more accurately referred to as Targeted Minimum Loss-Based Estimation) is a general statistical estimation framework for causal inference and semiparametric models. TMLE combines ideas from maximum likelihood estimation, semiparametric efficiency theory, and machine learning. It was introduced by Mark J. van der Laan and colleagues in the mid-2000s as a method that yields asymptotically efficient plug-in estimators while allowing the use of flexible, data-adaptive algorithms such as ensemble machine learning for nuisance parameter estimation. TMLE is used in epidemiology, biostatistics, and the social sciences to estimate causal effects in observational and experimental studies. Applications of TMLE include Longitudinal TMLE (LTMLE) for time-varying treatments and confounders. Variations in how the targeting step in TMLE is carried out have resulted in various versions of TMLE such as Collaborative TMLE (CTMLE) and Adaptive TMLE for improved finite-sample performance and automated variable selection. == History == The TMLE framework was first described by van der Laan and Rubin (2006) as a general approach for the construction of efficient plug-in estimators of smooth features of the data density. It was demonstrated in the context of causal inference and missing data problems. It was developed to address limitations of traditional doubly robust methods, such as Augmented Inverse Probability Weighting (AIPW), by respecting the plug-in principle in the sense that it respects that the target parameter is a function of the data density that is an element of the statistical model. TMLE estimates the data density or relevant parts of it with machine learning and targets these machine learning fits before it is plugged in the target parameter mapping. In this manner, a TMLE always respects global knowledge and satisfies known bounds such as that the target parameter is a probability . Since its introduction, TMLE has been developed in a series of theoretical and applied papers, culminating in book-length treatments of the method and its applications to survival analysis, adaptive designs, and longitudinal data. == Methodology == At its core, TMLE is a two-step estimation procedure: Initial estimation: Machine learning methods (such as the Super Learner ensemble) are used to obtain flexible estimates of nuisance parameters, such as outcome regressions and propensity scores. Targeting step: The initial estimate is updated by solving a score equation (the efficient influence function) so that the final estimator is consistent, asymptotically normal, and efficient under mild regularity conditions. The targeted machine learning fit is then mapped into the corresponding estimator of the target parameter by simply plugging it in the target parameter mapping. This approach balances the bias–variance trade-off by combining data-adaptive estimation with semiparametric efficiency theory. TMLE is doubly robust, meaning it remains consistent if either the outcome model or the treatment model is consistently estimated. === Formula === Here we explain the TMLE of the average treatment effect of a binary treatment on an outcome adjusting for baseline covariates. Consider i.i.d. observations O i = ( W i , A i , Y i ) {\displaystyle O_{i}=(W_{i},A_{i},Y_{i})} from a distribution P 0 {\displaystyle P_{0}} , where W {\displaystyle W} are baseline covariates, A {\displaystyle A} is a binary treatment, and Y {\displaystyle Y} is an outcome. Let Q ¯ ( a , w ) = E [ Y ∣ A = a , W = w ] {\displaystyle {\bar {Q}}(a,w)=\mathbb {E} [Y\mid A=a,W=w]} represent the outcome model and g ( a ∣ w ) = P ( A = a ∣ W = w ) {\displaystyle g(a\mid w)=P(A=a\mid W=w)} represent the propensity score. The average treatment effect (ATE) is given by ψ 0 = E { Q ¯ ( 1 , W ) − Q ¯ ( 0 , W ) } . {\displaystyle \psi _{0}=\mathbb {E} \{{\bar {Q}}(1,W)-{\bar {Q}}(0,W)\}.} A basic TMLE for the ATE proceeds as follows: Step 1: Estimate initial models. Obtain estimates Q ¯ ^ ( a , w ) {\displaystyle {\hat {\bar {Q}}}(a,w)} and g ^ ( a ∣ w ) {\displaystyle {\hat {g}}(a\mid w)} , often using flexible methods such as Super Learner. Step 2: Compute the clever covariate. Define: H ( A , W ) = A g ^ ( 1 ∣ W ) − 1 − A g ^ ( 0 ∣ W ) . {\displaystyle H(A,W)={\frac {A}{{\hat {g}}(1\mid W)}}-{\frac {1-A}{{\hat {g}}(0\mid W)}}.} Step 3: Estimate the fluctuation parameter. Fit a logistic regression of Y {\displaystyle Y} on H ( A , W ) {\displaystyle H(A,W)} with logit ⁡ ( Q ¯ ^ ( A , W ) ) {\displaystyle \operatorname {logit} ({\hat {\bar {Q}}}(A,W))} as offset. This yields ε ^ {\displaystyle {\hat {\varepsilon }}} , the MLE that solves the score equation: 1 n ∑ i = 1 n H ( A i , W i ) { Y i − Q ¯ ^ ε ( A i , W i ) } = 0. {\displaystyle {\frac {1}{n}}\sum _{i=1}^{n}H(A_{i},W_{i}){\big \{}Y_{i}-{\hat {\bar {Q}}}^{\varepsilon }(A_{i},W_{i}){\big \}}=0.} Step 4: Update the initial estimate. Apply the "blip" to obtain the targeted estimate: Q ¯ ^ ∗ ( A , W ) = expit ⁡ ( logit ⁡ ( Q ¯ ^ ( A , W ) ) + ε ^ H ( A , W ) ) . {\displaystyle {\hat {\bar {Q}}}^{}(A,W)=\operatorname {expit} {\Big (}\operatorname {logit} {\big (}{\hat {\bar {Q}}}(A,W){\big )}+{\hat {\varepsilon }}\,H(A,W){\Big )}.} Step 5: Compute the TMLE. The ATE estimate is: ψ ^ TMLE = 1 n ∑ i = 1 n [ Q ¯ ^ ∗ ( 1 , W i ) − Q ¯ ^ ∗ ( 0 , W i ) ] . {\displaystyle {\hat {\psi }}_{\text{TMLE}}={\frac {1}{n}}\sum _{i=1}^{n}{\big [}{\hat {\bar {Q}}}^{}(1,W_{i})-{\hat {\bar {Q}}}^{}(0,W_{i}){\big ]}.} Inference. The efficient influence function (EIF) for the ATE is: D ∗ ( O ) = H ( A , W ) { Y − Q ¯ ∗ ( A , W ) } + Q ¯ ∗ ( 1 , W ) − Q ¯ ∗ ( 0 , W ) − ψ . {\displaystyle D^{}(O)=H(A,W)\{Y-{\bar {Q}}^{}(A,W)\}+{\bar {Q}}^{}(1,W)-{\bar {Q}}^{}(0,W)-\psi .} The variance is estimated by σ ^ 2 = n − 1 ∑ i = 1 n ( D ∗ ( O i ) ) 2 {\displaystyle {\hat {\sigma }}^{2}=n^{-1}\sum _{i=1}^{n}{\big (}D^{}(O_{i}){\big )}^{2}} , yielding Wald-type confidence intervals ψ ^ TMLE ± z 1 − α / 2 σ ^ / n {\displaystyle {\hat {\psi }}_{\text{TMLE}}\pm z_{1-\alpha /2}\,{\hat {\sigma }}/{\sqrt {n}}} . Remark. For continuous outcomes, a linear fluctuation Q ¯ ^ ∗ = Q ¯ ^ + ε ^ H {\displaystyle {\hat {\bar {Q}}}^{}={\hat {\bar {Q}}}+{\hat {\varepsilon }}\,H} may be used instead. For bounded continuous outcomes, the logistic fluctuation (after rescaling Y {\displaystyle Y} to [ 0 , 1 ] {\displaystyle [0,1]} ) is often preferred for improved finite-sample performance. == Applications == TMLE has been applied in: Epidemiology: Estimating causal effects of exposures and interventions in observational cohort studies. Clinical trials and real-world evidence: The Targeted Learning roadmap provides a structured framework for generating and validating real-world evidence (RWE), bridging randomized trials and observational data using TMLE and related estimation techniques. This approach enables transparency, sensitivity analysis, and stronger causal inference for regulatory and clinical trial contexts. High-dimensional settings: Integration with ensemble methods for causal effect estimation. TMLE has been successfully applied in pharmacoepidemiology where a large number of covariates are automatically selected to adjust for confounding. In a study of post–myocardial infarction statin use and 1-year mortality, TMLE demonstrated robust performance relative to inverse probability weighting in scenarios with hundreds of potential confounders. == Derivatives and extensions == Longitudinal TMLE (LTMLE): A methodological extension of TMLE for longitudinal data with time-varying treatments, confounders, and censoring. It allows the estimation of dynamic treatment regimes and intervention-specific causal effects over time. This framework was originally introduced by van der Laan & Gruber (2012). Collaborative TMLE (CTMLE): Enhances finite-sample performance and variable selection by collaboratively fitting the treatment mechanism in conjunction with the target parameter. == Software == Several R packages implement TMLE and related methods: tmle: Functions for binary, categorical, and continuous outcomes. ltmle: Implementation for longitudinal data with time-varying treatments and outcomes. ctmle: Algorithms for collaborative TMLE and adaptive variable selection. SuperLearner: A theoretically grounded, cross-validated ensemble learning method that combines predictions from multiple algorithms to minimize predictive risk. Widely used in TMLE for estimating nuisance parameters. The original implementation is available as the R package SuperLearner. Recent machine learning platforms like H2O AutoML implement similar ensemble strategies, combining diverse learners in parallel and leveraging stacking and blending techniques, effectively functioning as a large-scale Super Learner.

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  Information Harvesting

  Information Harvesting (IH) was an early data mining product from the 1990s. It was invented by Ralphe Wiggins and produced by the Ryan Corp, later Information Harvesting Inc., of Cambridge, Massachusetts. Wiggins had a background in genetic algorithms and fuzzy logic. IH sought to infer rules from sets of data. It did this first by classifying various input variables into one of a number of bins, thereby putting some structure on the continuous variables in the input. IH then proceeds to generate rules, trading off generalization against memorization, that will infer the value of the prediction variable, possibly creating many levels of rules in the process. It included strategies for checking if overfitting took place and, if so, correcting for it. Because of its strategies for correcting for overfitting by considering more data, and refining the rules based on that data, IH might also be considered to be a form of machine learning. The advantage of IH, as compared with other data mining products of its time and even later, was that it provided a mechanism for finding multiple rules that would classify the data and determining, according to set criteria, the best rules to use.

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  ReactiveX

  ReactiveX (Rx, also known as Reactive Extensions) is a software library originally created by Microsoft that allows imperative programming languages to operate on sequences of data regardless of whether the data is synchronous or asynchronous. It provides a set of sequence operators that operate on each item in the sequence. It is an implementation of reactive programming and provides a blueprint for the tools to be implemented in multiple programming languages. == Overview == ReactiveX is an API for asynchronous programming with observable streams. Asynchronous programming allows programmers to call functions and then have the functions "callback" when they are done, usually by giving the function the address of another function to execute when it is done. Programs designed in this way often avoid the overhead of having many threads constantly starting and stopping. Observable streams (i.e. streams that can be observed) in the context of Reactive Extensions are like event emitters that emit three events: next, error, and complete. An observable emits next events until it either emits an error event or a complete event. However, at that point it will not emit any more events, unless it is subscribed to again. The examples below use the RxJS implementation of Reactive Extensions for the JavaScript programming language. === Motivation === For sequences of data, it combines the advantages of iterators with the flexibility of event-based asynchronous programming. It also works as a simple promise, eliminating the pyramid of doom that results from multiple layers of callbacks. === Observables and observers === ReactiveX is a combination of ideas from the observer and the iterator patterns and from functional programming. An observer subscribes to an observable sequence. The sequence then sends the items to the observer one at a time, usually by calling the provided callback function. The observer handles each one before processing the next one. If many events come in asynchronously, they must be stored in a queue or dropped. In ReactiveX, an observer will never be called with an item out of order or (in a multi-threaded context) called before the callback has returned for the previous item. Asynchronous calls remain asynchronous and may be handled by returning an observable. It is similar to the iterators pattern in that if a fatal error occurs, it notifies the observer separately (by calling a second function). When all the items have been sent, it completes (and notifies the observer by calling a third function). The Reactive Extensions API also borrows many of its operators from iterator operators in other programming languages. Reactive Extensions is different from functional reactive programming as the Introduction to Reactive Extensions explains: It is sometimes called "functional reactive programming" but this is a misnomer. ReactiveX may be functional, and it may be reactive, but "functional reactive programming" is a different animal. One main point of difference is that functional reactive programming operates on values that change continuously over time, while ReactiveX operates on discrete values that are emitted over time. (See Conal Elliott's work for more-precise information on functional reactive programming.) === Reactive operators === An operator is a function that takes one observable (the source) as its first argument and returns another observable (the destination, or outer observable). Then for every item that the source observable emits, it will apply a function to that item, and then emit it on the destination Observable. It can even emit another Observable on the destination observable. This is called an inner observable. An operator that emits inner observables can be followed by another operator that in some way combines the items emitted by all the inner observables and emits the item on its outer observable. Examples include: switchAll – subscribes to each new inner observable as soon as it is emitted and unsubscribes from the previous one. mergeAll – subscribes to all inner observables as they are emitted and outputs their values in whatever order it receives them. concatAll – subscribes to each inner observable in order and waits for it to complete before subscribing to the next observable. Operators can be chained together to create complex data flows that filter events based on certain criteria. Multiple operators can be applied to the same observable. Some of the operators that can be used in Reactive Extensions may be familiar to programmers who use functional programming language, such as map, reduce, group, and zip. There are many other operators available in Reactive Extensions, though the operators available in a particular implementation for a programming language may vary. ==== Reactive operator examples ==== Here is an example of using the map and reduce operators. We create an observable from a list of numbers. The map operator will then multiply each number by two and return an observable. The reduce operator will then sum up all the numbers provided to it (the value of 0 is the starting point). Calling subscribe will register an observer that will observe the values from the observable produced by the chain of operators. With the subscribe method, we are able to pass in an error-handling function, called whenever an error is emitted in the observable, and a completion function when the observable has finished emitting items. ==== Usage in stream-oriented programming ==== Certain RxJS primitives such as BehaviorSubject make it possible to create pure stateful streams to track application state of arbitrary complexity in simple terms. The button below will feed an event to the stream, which in turn will re-emit the next natural number every time, back into the tag that follows and displays the count of clicks detected. Libraries such as Rimmel.js, designed around RxJS Observables, enable integration between reactive streams and the HTML DOM: == History == Reactive Extensions was created by the Cloud Programmability Team at Microsoft around 2011, as a byproduct of a larger effort called Volta. It was originally intended to provide an abstraction for events across different tiers in an application to support tier splitting in Volta. The project's logo represents an electric eel, which is a reference to Volta. The extensions suffix in the name is a reference to the Parallel Extensions technology which was invented around the same time; the two are considered complementary. The initial implementation of Rx was for .NET Framework and was released on June 21, 2011. Later, the team started the implementation of Rx for other platforms, including JavaScript and C++. The technology was released as open source in late 2012, initially on CodePlex. Later, the code moved to GitHub and has been ported to several other languages, including Go, Java, Kotlin, PHP and Rust.

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  World Programming System

  The World Programming System, also known as WPS Analytics or WPS, is a software product developed by a company called World Programming (acquired by Altair Engineering). WPS Analytics supports users of mixed ability to access and process data and to perform data science tasks. It has interactive visual programming tools using data workflows, and it has coding tools supporting the use of the SAS language mixed with Python, R and SQL. == About == WPS can use programs written in the language of SAS without the need for translating them into any other language. In this regard WPS is compatible with the SAS system. WPS has a built-in language interpreter able to process the language of SAS and produce similar results. WPS is available to run on z/OS, Windows, macOS, Linux (x86, Armv8 64-bit, IBM Power LE, IBM Z), and AIX. On all supported platforms, programs written in the language of SAS can be executed from a WPS command line interface, often referred to as running in batch mode. WPS can also be used from a graphical user interface known as the WPS Workbench for managing, editing and running programs written in the language of SAS. The WPS Workbench user interface is based on Eclipse. WPS version 4 (released in March 2018) introduced a drag-and-drop workflow canvas providing interactive blocks for data retrieval, blending and preparation, data discovery and profiling, predictive modelling powered by machine learning algorithms, model performance validation and scorecards. WPS version 3 (released in February 2012) provided a new client/server architecture that allows the WPS Workbench GUI to execute SAS programs on remote server installations of WPS in a network or cloud. The resulting output, data sets, logs, etc., can then all be viewed and manipulated from inside the Workbench as if the workloads had been executed locally. SAS programs do not require any special language statements to use this feature. == Summary of main features == Runs on Windows, macOS, z/OS, Linux (x86, Armv8 64-bit, IBM Power LE, IBM Z), and AIX An integrated development environment based on Eclipse for Linux, macOS and Windows. Support for language of SAS elements. Support for the language of SAS Macros. Matrix Programming support using PROC IML. Support for generating band plots, bar charts, box plots, bubble plots, contour plots, dendrogram plots, ellipse plots, fringe plots, heat maps, high-low plots, histograms, loess plots, needle plots, pie charts, penalised b-spline, radar charts, reference lines, scatter plots, series plots, step plots, regression plots and vector plots. Support for statistical procedures ACECLUS, ASSOCRULES, ANOVA, BIN, BOXPLOT, CANCORR, CANDISC, CLUSTER, CORRESP, DISCRIM, DISTANCE, FACTOR, FASTCLUS, FREQ, GAM, GANNO, GENMOD, GLIMMIX, GLM, GLMMOD, GLMSELECT, ICLIFETEST, KDE, LIFEREG, LIFETEST, LOESS, LOGISTIC, MDS, MEANS, MI, MIANALYSE, MIXED, MODECLUS, NESTED, NLIN, NPAR1WAY, PHREG, PLAN, PLS, POWER, PRINCOMP, PROBIT, QUANTREG, RBF, REG, ROBUSTREG, RSREG, SCORE, SEGMENT, SIMNORMAL, STANDARD, STDSIZE, STDRATE, STEPDISC, SUMMARY, SURVEYMEANS, SURVEYSELECT, TPSPLINE, TRANSREG, TREE, TTEST, UNIVARIATE, VARCLUS, VARCOMP Support for time series procedures ARIMA, AUTOREG, ESM, EXPAND, FORECAST, LOAN, SEVERITY, SPECTRA, TIMESERIES, X12 Support for machine learning procedures DECISIONFOREST, DECISIONTREE, GMM, MLP, OPTIMALBIN, SEGMENT, SVM Support for ODS. Reads and writes SAS datasets (compressed or uncompressed). Access: Actian Matrix (previously known as ParAccel), DASD, DB2, Excel, Greenplum, Hadoop, Informix, Kognitio Archived 2012-08-24 at the Wayback Machine, MariaDB, MySQL, Netezza, ODBC, OLEDB, Oracle, PostgreSQL, SAND, Snowflake, SPSS/PSPP, SQL Server, Sybase, Sybase IQ, Teradata, VSAM, Vertica and XML. Support for SAS Tape Format. Direct output of reports to CSV, PDF and HTML. Support to connect WPS systems programmatically, remote submit parts of a program to execute on connected remote servers, upload and download data between the connected systems. Support for Hadoop Support for R Support for Python == Industry recognition == Gartner recognized World Programming in their Cool Vendors in Data Science, 2014 Report. == Lawsuit == In 2010 World Programming defended its use of the language of SAS in the High Court of England and Wales in SAS Institute Inc. v World Programming Ltd. The software was the subject of a lawsuit by SAS Institute. The EU Court of Justice ruled in favor of World Programming, stating that the copyright protection does not extend to the software functionality, the programming language used and the format of the data files used by the program. It stated that there is no copyright infringement when a company which does not have access to the source code of a program studies, observes and tests that program to create another program with the same functionality.

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  Facial recognition system

  A facial recognition system is a technology potentially capable of matching a human face from a digital image or a video frame against a database of faces. Such a system is typically employed to authenticate users through ID verification services, and works by pinpointing and measuring facial features from a given image. Development on similar systems began in the 1960s as a form of computer application. Since their inception, facial recognition systems have seen wider uses in recent times on smartphones and in other forms of technology, such as robotics. Because computerized facial recognition involves the measurement of a human's physiological characteristics, facial recognition systems are categorized as biometrics. Although the accuracy of facial recognition systems as a biometric technology is lower than iris recognition, fingerprint image acquisition, palm recognition or voice recognition, it is widely adopted due to its contactless process. Facial recognition systems have been deployed in advanced human–computer interaction, video surveillance, law enforcement, passenger screening, decisions on employment and housing, and automatic indexing of images. Facial recognition systems are employed throughout the world today by governments and private companies. Their effectiveness varies, and some systems have previously been scrapped because of their ineffectiveness. The use of facial recognition systems has also raised controversy, with claims that the systems violate citizens' privacy, commonly make incorrect identifications, encourage gender norms and racial profiling, and do not protect important biometric data. The appearance of synthetic media such as deepfakes has also raised concerns about its security. These claims have led to the ban of facial recognition systems in several cities in the United States. Growing societal concerns led social networking company Meta Platforms to shut down its Facebook facial recognition system in 2021, deleting the face-scan data of more than one billion users. The change represented one of the largest shifts in facial recognition usage in the technology's history. IBM also stopped offering facial recognition technology due to similar concerns. == History of facial recognition technology == Automated facial recognition was pioneered in the 1960s by Woody Bledsoe, Helen Chan Wolf, and Charles Bisson, whose work focused on teaching computers to recognize human faces. Their early facial recognition project was dubbed "man-machine" because a human first needed to establish the coordinates of facial features in a photograph before they could be used by a computer for recognition. Using a graphics tablet, a human would pinpoint facial features coordinates, such as the pupil centers, the inside and outside corners of eyes, and the widows peak in the hairline. The coordinates were used to calculate 20 individual distances, including the width of the mouth and of the eyes. A human could process about 40 pictures an hour, building a database of these computed distances. A computer would then automatically compare the distances for each photograph, calculate the difference between the distances, and return the closed records as a possible match. In 1970, Takeo Kanade publicly demonstrated a face-matching system that located anatomical features such as the chin and calculated the distance ratio between facial features without human intervention. Later tests revealed that the system could not always reliably identify facial features. Nonetheless, interest in the subject grew and in 1977 Kanade published the first detailed book on facial recognition technology. In 1993, the Defense Advanced Research Project Agency (DARPA) and the Army Research Laboratory (ARL) established the face recognition technology program FERET to develop "automatic face recognition capabilities" that could be employed in a productive real life environment "to assist security, intelligence, and law enforcement personnel in the performance of their duties." Face recognition systems that had been trialled in research labs were evaluated. The FERET tests found that while the performance of existing automated facial recognition systems varied, a handful of existing methods could viably be used to recognize faces in still images taken in a controlled environment. The FERET tests spawned three US companies that sold automated facial recognition systems. Vision Corporation and Miros Inc were founded in 1994, by researchers who used the results of the FERET tests as a selling point. Viisage Technology was established by an identification card defense contractor in 1996 to commercially exploit the rights to the facial recognition algorithm developed by Alex Pentland at MIT. Following the 1993 FERET face-recognition vendor test, the Department of Motor Vehicles (DMV) offices in West Virginia and New Mexico became the first DMV offices to use automated facial recognition systems to prevent people from obtaining multiple driving licenses using different names. Driver's licenses in the United States were at that point a commonly accepted form of photo identification. DMV offices across the United States were undergoing a technological upgrade and were in the process of establishing databases of digital ID photographs. This enabled DMV offices to deploy the facial recognition systems on the market to search photographs for new driving licenses against the existing DMV database. DMV offices became one of the first major markets for automated facial recognition technology and introduced US citizens to facial recognition as a standard method of identification. The increase of the US prison population in the 1990s prompted U.S. states to established connected and automated identification systems that incorporated digital biometric databases, in some instances this included facial recognition. In 1999, Minnesota incorporated the facial recognition system FaceIT by Visionics into a mug shot booking system that allowed police, judges and court officers to track criminals across the state. Until the 1990s, facial recognition systems were developed primarily by using photographic portraits of human faces. Research on face recognition to reliably locate a face in an image that contains other objects gained traction in the early 1990s with the principal component analysis (PCA). The PCA method of face detection is also known as Eigenface and was developed by Matthew Turk and Alex Pentland. Turk and Pentland combined the conceptual approach of the Karhunen–Loève theorem and factor analysis, to develop a linear model. Eigenfaces are determined based on global and orthogonal features in human faces. A human face is calculated as a weighted combination of a number of Eigenfaces. Because few Eigenfaces were used to encode human faces of a given population, Turk and Pentland's PCA face detection method greatly reduced the amount of data that had to be processed to detect a face. Pentland in 1994 defined Eigenface features, including eigen eyes, eigen mouths and eigen noses, to advance the use of PCA in facial recognition. In 1997, the PCA Eigenface method of face recognition was improved upon using linear discriminant analysis (LDA) to produce Fisherfaces. LDA Fisherfaces became dominantly used in PCA feature based face recognition. While Eigenfaces were also used for face reconstruction. In these approaches no global structure of the face is calculated which links the facial features or parts. Purely feature based approaches to facial recognition were overtaken in the late 1990s by the Bochum system, which used Gabor filter to record the face features and computed a grid of the face structure to link the features. Christoph von der Malsburg and his research team at the University of Bochum developed Elastic Bunch Graph Matching in the mid-1990s to extract a face out of an image using skin segmentation. By 1997, the face detection method developed by Malsburg outperformed most other facial detection systems on the market. The so-called "Bochum system" of face detection was sold commercially on the market as ZN-Face to operators of airports and other busy locations. The software was "robust enough to make identifications from less-than-perfect face views. It can also often see through such impediments to identification as mustaches, beards, changed hairstyles and glasses—even sunglasses". Real-time face detection in video footage became possible in 2001 with the Viola–Jones object detection framework for faces. Paul Viola and Michael Jones combined their face detection method with the Haar-like feature approach to object recognition in digital images to launch AdaBoost, the first real-time frontal-view face detector. By 2015, the Viola–Jones algorithm had been implemented using small low power detectors on handheld devices and embedded systems. Therefore, the Viola–Jones algorithm has not only broadened the practical application of face recognition systems but

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  Charge based boundary element fast multipole method

  The charge-based formulation of the boundary element method (BEM) is a dimensionality reduction numerical technique that is used to model quasistatic electromagnetic phenomena in highly complex conducting media (targeting, e.g., the human brain) with a very large (up to approximately 1 billion) number of unknowns. The charge-based BEM solves an integral equation of the potential theory written in terms of the induced surface charge density. This formulation is naturally combined with fast multipole method (FMM) acceleration, and the entire method is known as charge-based BEM-FMM. The combination of BEM and FMM is a common technique in different areas of computational electromagnetics and, in the context of bioelectromagnetism, it provides improvements over the finite element method. == Historical development == Along with more common electric potential-based BEM, the quasistatic charge-based BEM, derived in terms of the single-layer (charge) density, for a single-compartment medium has been known in the potential theory since the beginning of the 20th century. For multi-compartment conducting media, the surface charge density formulation first appeared in discretized form (for faceted interfaces) in the 1964 paper by Gelernter and Swihart. A subsequent continuous form, including time-dependent and dielectric effects, appeared in the 1967 paper by Barnard, Duck, and Lynn. The charge-based BEM has also been formulated for conducting, dielectric, and magnetic media, and used in different applications. In 2009, Greengard et al. successfully applied the charge-based BEM with fast multipole acceleration to molecular electrostatics of dielectrics. A similar approach to realistic modeling of the human brain with multiple conducting compartments was first described by Makarov et al. in 2018. Along with this, the BEM-based multilevel fast multipole method has been widely used in radar and antenna studies at microwave frequencies as well as in acoustics. == Physical background - surface charges in biological media == The charge-based BEM is based on the concept of an impressed (or primary) electric field E i {\displaystyle \mathbf {E} ^{i}} and a secondary electric field E s {\displaystyle \mathbf {E} ^{s}} . The impressed field is usually known a priori or is trivial to find. For the human brain, the impressed electric field can be classified as one of the following: A conservative field E i {\displaystyle \mathbf {E} ^{i}} derived from an impressed density of EEG or MEG current sources in a homogeneous infinite medium with the conductivity σ {\displaystyle \sigma } at the source location; An instantaneous solenoidal field E i {\displaystyle \mathbf {E} ^{i}} of an induction coil obtained from Faraday's law of induction in a homogeneous infinite medium (air), when transcranial magnetic stimulation (TMS) problems are concerned; A surface field E i {\displaystyle \mathbf {E} ^{i}} derived from an impressed surface current density J i = σ E i {\displaystyle \mathbf {J} ^{i}=\sigma \mathbf {E} ^{i}} of current electrodes injecting electric current at a boundary of a compartment with conductivity σ {\displaystyle \sigma } when transcranial direct-current stimulation (tDCS) or deep brain stimulation (DBS) are concerned; A conservative field E i {\displaystyle \mathbf {E} ^{i}} of charges deposited on voltage electrodes for tDCS or DBS. This specific problem requires a coupled treatment since these charges will depend on the environment; In application to multiscale modeling, a field E i {\displaystyle \mathbf {E} ^{i}} obtained from any other macroscopic numerical solution in a small (mesoscale or microscale) spatial domain within the brain. For example, a constant field can be used. When the impressed field is "turned on", free charges located within a conducting volume D immediately begin to redistribute and accumulate at the boundaries (interfaces) of regions of different conductivity in D. A surface charge density ρ ( r ) {\displaystyle \rho (\mathbf {r} )} appears on the conductivity interfaces. This charge density induces a secondary conservative electric field E s {\displaystyle \mathbf {E} ^{s}} following Coulomb's law. One example is a human under a direct current powerline with the known field E i {\displaystyle \mathbf {E} ^{i}} directed down. The superior surface of the human's conducting body will be charged negatively while its inferior portion is charged positively. These surface charges create a secondary electric field that effectively cancels or blocks the primary field everywhere in the body so that no current will flow within the body under DC steady state conditions. Another example is a human head with electrodes attached. At any conductivity interface with a normal vector n {\displaystyle \mathbf {n} } pointing from an "inside" (-) compartment of conductivity σ − {\displaystyle \sigma ^{-}} to an "outside" (+) compartment of conductivity σ + {\displaystyle \sigma ^{+}} , Kirchhoff's current law requires continuity of the normal component of the electric current density. This leads to the interfacial boundary condition in the form for every facet at a triangulated interface. As long as σ ± {\displaystyle \sigma ^{\pm }} are different from each other, the two normal components of the electric field, E ± ⋅ n {\displaystyle \mathbf {E} ^{\pm }\cdot \mathbf {n} } , must also be different. Such a jump across the interface is only possible when a sheet of surface charge exists at that interface. Thus, if an electric current or voltage is applied, the surface charge density follows. The goal of the numerical analysis is to find the unknown surface charge distribution and thus the total electric field E = E i + E s {\displaystyle \mathbf {E} =\mathbf {E} ^{i}+\mathbf {E} ^{s}} (and the total electric potential if required) anywhere in space. == System of equations for surface charges == Below, a derivation is given based on Gauss's law and Coulomb's law. All conductivity interfaces, denoted by S, are discretized into planar triangular facets t m {\displaystyle t_{m}} with centers r m {\displaystyle \mathbf {r} _{m}} . Assume that an m-th facet with the normal vector n m {\displaystyle \mathbf {n} _{m}} and area A m {\displaystyle A_{m}} carries a uniform surface charge density ρ m {\displaystyle \rho _{m}} . If a volumetric tetrahedral mesh were present, the charged facets would belong to tetrahedra with different conductivity values. We first compute the electric field E m + {\displaystyle \mathbf {E} _{m}^{+}} at the point r m + δ n m {\displaystyle \mathbf {r} _{m}+\delta \mathbf {n} _{m}} , for δ → 0 + {\displaystyle \delta \rightarrow 0^{+}} i.e., just outside facet 𝑚 at its center. This field contains three contributions: The continuous impressed electric field E i {\displaystyle \mathbf {E} ^{i}} itself; An electric field of the m-th charged facet itself. Very close to the facet, it can be approximated as the electric field of an infinite sheet of uniform surface charge ρ m {\displaystyle \rho _{m}} . By Gauss's law, it is given by + ρ m / 2 ε 0 ⋅ n m {\displaystyle +\rho _{m}/2\varepsilon _{0}\cdot \mathbf {n} _{m}} where ε 0 {\displaystyle \varepsilon _{0}} is a background electrical permittivity; An electric field generated by all other facets t n {\displaystyle t_{n}} , which we approximate as point charges of charge A n ρ n {\displaystyle A_{n}\rho _{n}} at each center r n {\displaystyle \mathbf {r} _{n}} . A similar treatment holds for the electric field E m − {\displaystyle \mathbf {E} _{m}^{-}} just inside facet 𝑚, but the electric field of the flat sheet of charge changes its sign. Using Coulomb's law to calculate the contribution of facets different from t m {\displaystyle t_{m}} , we find From this equation, we see that the normal component of the electric field indeed undergoes a jump through the charged interface. This is equivalent to a jump relation of the potential theory. As a second step, the two expressions for E m ± {\displaystyle \mathbf {E} _{m}^{\pm }} are substituted into the interfacial boundary condition σ − E m − ⋅ n m = σ + E m + ⋅ n m {\displaystyle \sigma ^{-}\mathbf {E} _{m}^{-}\cdot \mathbf {n} _{m}=\sigma ^{+}\mathbf {E} _{m}^{+}\cdot \mathbf {n} _{m}} , applied to every facet 𝑚. This operation leads to a system of linear equations for unknown charge densities ρ m {\displaystyle \rho _{m}} which solves the problem: where K m = σ − − σ + σ − + σ + {\displaystyle K_{m}={\frac {\sigma ^{-}-\sigma ^{+}}{\sigma ^{-}+\sigma ^{+}}}} is the electric conductivity contrast at the m-th facet. The normalization constant ε 0 {\displaystyle \varepsilon _{0}} will cancel out after the solution is substituted in the expression for E s {\displaystyle \mathbf {E} ^{s}} and becomes redundant. == Application of fast multipole method == For modern characterizations of brain topologies with ever-increasing levels of complexity, the above system of equations for ρ m {\displaystyle \rho _{m}} is very large; it is t

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  Showbox.com

  Showbox is an online video streaming platform that enables users to stream and download many videos, commonly movies and TV shows, for free. == History == The company opened the platforms to users who registered from its beta in late 2015. The platform was officially launched in February 2016, enabling any visitor to sign up and create videos online. In April 2016, Showbox was featured on the Product Hunt website, coming to the top of the website's lists for that day and week with over 1400 upvotes from the Product Hunt community. Also in April 2016, Showbox partnered with YouTube's leading multi-channel networks, including Fullscreen, BroadbandTV, StyleHaul, AwesomenessTV, and BuzzMyVideos, to enable their communities of creators to access the platform. In June 2016, the company launched Showbox For Brands, a business-oriented video creation platform, enabling companies to create video content in-house and with their communities and influencers. In March 2017, the company launched Showbox Engage, a use case of its B2B product launched in 2016, enabling companies to launch user-generated content campaigns with their communities. In April 2017, Showbox and the United Nations announced a partnership around the 70th anniversary of the declaration of human rights, with an annual, ongoing global campaign in 135 languages, inviting people worldwide to create their part of the declaration in a video from anywhere around the world. In November 2017, Showbox partnered with the Ad:tech and Digital Marketing World Forum conferences (DMWF) in New York to provide their users and communities with a User Generated Content video solution. == Technology == Showbox's video creation technology includes an online green screen feature, proprietary computer vision algorithms, deep learning technology to support the automatic creation of videos in the cloud, and advanced video composition, including special effects. == Coverage and awards == In March 2015, Showbox was nominated as one of the 10 Israeli startups to take over our TV screens this year. In July 2016, Showbox won the Publicis90 award as part of Publicis' "global initiative to foster digital entrepreneurship". In March 2017, Showbox was chosen as one of The Culture Trip's 10 startups to watch for in 2017.

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  Linguamatics

  Linguamatics, headquartered in Cambridge, England, with offices in the United States and UK, is a provider of text mining systems through software licensing and services, primarily for pharmaceutical and healthcare applications. Founded in 2001, the company was purchased by IQVIA in January 2019. == Technology == The company develops enterprise search tools for the life sciences sector. The core natural language processing engine (I2E) uses a federated architecture to incorporate data from 3rd party resources. Initially developed to be used interactively through a graphic user interface, the core software also has an application programming interface that can be used to automate searches. LabKey, Penn Medicine, Atrius Health and Mercy all use Linguamatics software to extract electronic health record data into data warehouses. Linguamatics software is used by 17 of the top 20 global pharmaceutical companies, the US Food and Drug Administration, as well as healthcare providers. == Software community == The core software, "I2E", is used by a number of companies to either extend their own software or to publish their data. Copyright Clearance Center uses I2E to produce searchable indexes of material that would otherwise be unsearchable due to copyright. Thomson Reuters produces Cortellis Informatics Clinical Text Analytics, which depends on I2E to make clinical data accessible and searchable. Pipeline Pilot can integrate I2E as part of a workflow. ChemAxon can be used alongside I2E to allow named entity recognition of chemicals within unstructured data. Data sources include MEDLINE, ClinicalTrials.gov, FDA Drug Labels, PubMed Central, and Patent Abstracts.

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  Relief (feature selection)

  Relief is an algorithm developed by Kenji Kira and Larry Rendell in 1992 that takes a filter-method approach to feature selection that is notably sensitive to feature interactions. It was originally designed for application to binary classification problems with discrete or numerical features. Relief calculates a feature score for each feature which can then be applied to rank and select top scoring features for feature selection. Alternatively, these scores may be applied as feature weights to guide downstream modeling. Relief feature scoring is based on the identification of feature value differences between nearest neighbor instance pairs. If a feature value difference is observed in a neighboring instance pair with the same class (a 'hit'), the feature score decreases. Alternatively, if a feature value difference is observed in a neighboring instance pair with different class values (a 'miss'), the feature score increases. The original Relief algorithm has since inspired a family of Relief-based feature selection algorithms (RBAs), including the ReliefF algorithm. Beyond the original Relief algorithm, RBAs have been adapted to (1) perform more reliably in noisy problems, (2) generalize to multi-class problems (3) generalize to numerical outcome (i.e. regression) problems, and (4) to make them robust to incomplete (i.e. missing) data. To date, the development of RBA variants and extensions has focused on four areas; (1) improving performance of the 'core' Relief algorithm, i.e. examining strategies for neighbor selection and instance weighting, (2) improving scalability of the 'core' Relief algorithm to larger feature spaces through iterative approaches, (3) methods for flexibly adapting Relief to different data types, and (4) improving Relief run efficiency. Their strengths are that they are not dependent on heuristics, they run in low-order polynomial time, and they are noise-tolerant and robust to feature interactions, as well as being applicable for binary or continuous data; however, it does not discriminate between redundant features, and low numbers of training instances fool the algorithm. == Relief Algorithm == Take a data set with n instances of p features, belonging to two known classes. Within the data set, each feature should be scaled to the interval [0 1] (binary data should remain as 0 and 1). The algorithm will be repeated m times. Start with a p-long weight vector (W) of zeros. At each iteration, take the feature vector (X) belonging to one random instance, and the feature vectors of the instance closest to X (by Euclidean distance) from each class. The closest same-class instance is called 'near-hit', and the closest different-class instance is called 'near-miss'. Update the weight vector such that W i = W i − ( x i − n e a r H i t i ) 2 + ( x i − n e a r M i s s i ) 2 , {\displaystyle W_{i}=W_{i}-(x_{i}-\mathrm {nearHit} _{i})^{2}+(x_{i}-\mathrm {nearMiss} _{i})^{2},} where i {\displaystyle i} indexes the components and runs from 1 to p. Thus the weight of any given feature decreases if it differs from that feature in nearby instances of the same class more than nearby instances of the other class, and increases in the reverse case. After m iterations, divide each element of the weight vector by m. This becomes the relevance vector. Features are selected if their relevance is greater than a threshold τ. Kira and Rendell's experiments showed a clear contrast between relevant and irrelevant features, allowing τ to be determined by inspection. However, it can also be determined by Chebyshev's inequality for a given confidence level (α) that a τ of 1/sqrt(αm) is good enough to make the probability of a Type I error less than α, although it is stated that τ can be much smaller than that. Relief was also described as generalizable to multinomial classification by decomposition into a number of binary problems. == ReliefF Algorithm == Kononenko et al. propose a number of updates to Relief. Firstly, they find the near-hit and near-miss instances using the Manhattan (L1) norm rather than the Euclidean (L2) norm, although the rationale is not specified. Furthermore, they found taking the absolute differences between xi and near-hiti, and xi and near-missi to be sufficient when updating the weight vector (rather than the square of those differences). === Reliable probability estimation === Rather than repeating the algorithm m times, implement it exhaustively (i.e. n times, once for each instance) for relatively small n (up to one thousand). Furthermore, rather than finding the single nearest hit and single nearest miss, which may cause redundant and noisy attributes to affect the selection of the nearest neighbors, ReliefF searches for k nearest hits and misses and averages their contribution to the weights of each feature. k can be tuned for any individual problem. === Incomplete data === In ReliefF, the contribution of missing values to the feature weight is determined using the conditional probability that two values should be the same or different, approximated with relative frequencies from the data set. This can be calculated if one or both features are missing. === Multi-class problems === Rather than use Kira and Rendell's proposed decomposition of a multinomial classification into a number of binomial problems, ReliefF searches for k near misses from each different class and averages their contributions for updating W, weighted with the prior probability of each class. == Other Relief-based Algorithm Extensions/Derivatives == The following RBAs are arranged chronologically from oldest to most recent. They include methods for improving (1) the core Relief algorithm concept, (2) iterative approaches for scalability, (3) adaptations to different data types, (4) strategies for computational efficiency, or (5) some combination of these goals. For more on RBAs see these book chapters or this most recent review paper. === RRELIEFF === Robnik-Šikonja and Kononenko propose further updates to ReliefF, making it appropriate for regression. === Relieved-F === Introduced deterministic neighbor selection approach and a new approach for incomplete data handling. === Iterative Relief === Implemented method to address bias against non-monotonic features. Introduced the first iterative Relief approach. For the first time, neighbors were uniquely determined by a radius threshold and instances were weighted by their distance from the target instance. === I-RELIEF === Introduced sigmoidal weighting based on distance from target instance. All instance pairs (not just a defined subset of neighbors) contributed to score updates. Proposed an on-line learning variant of Relief. Extended the iterative Relief concept. Introduced local-learning updates between iterations for improved convergence. === TuRF (a.k.a. Tuned ReliefF) === Specifically sought to address noise in large feature spaces through the recursive elimination of features and the iterative application of ReliefF. === Evaporative Cooling ReliefF === Similarly seeking to address noise in large feature spaces. Utilized an iterative `evaporative' removal of lowest quality features using ReliefF scores in association with mutual information. === EReliefF (a.k.a. Extended ReliefF) === Addressing issues related to incomplete and multi-class data. === VLSReliefF (a.k.a. Very Large Scale ReliefF) === Dramatically improves the efficiency of detecting 2-way feature interactions in very large feature spaces by scoring random feature subsets rather than the entire feature space. === ReliefMSS === Introduced calculation of feature weights relative to average feature 'diff' between instance pairs. === SURF === SURF identifies nearest neighbors (both hits and misses) based on a distance threshold from the target instance defined by the average distance between all pairs of instances in the training data. Results suggest improved power to detect 2-way epistatic interactions over ReliefF. === SURF (a.k.a. SURFStar) === SURF extends the SURF algorithm to not only utilized 'near' neighbors in scoring updates, but 'far' instances as well, but employing inverted scoring updates for 'far instance pairs. Results suggest improved power to detect 2-way epistatic interactions over SURF, but an inability to detect simple main effects (i.e. univariate associations). === SWRF === SWRF extends the SURF algorithm adopting sigmoid weighting to take distance from the threshold into account. Also introduced a modular framework for further developing RBAs called MoRF. === MultiSURF (a.k.a. MultiSURFStar) === MultiSURF extends the SURF algorithm adapting the near/far neighborhood boundaries based on the average and standard deviation of distances from the target instance to all others. MultiSURF uses the standard deviation to define a dead-band zone where 'middle-distance' instances do not contribute to scoring. Evidence suggests MultiSURF performs best in detecting pure 2-way feature interactions. === Reli

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  Vapnik–Chervonenkis dimension

  In Vapnik–Chervonenkis theory, the Vapnik–Chervonenkis (VC) dimension is a measure of the size (capacity, complexity, expressive power, richness, or flexibility) of a class of sets. The notion can be extended to classes of binary functions. It is defined as the cardinality of the largest set of points that the function class can shatter—that is, for which all possible binary labelings can be realized by some function in the class. It was originally defined by Vladimir Vapnik and Alexey Chervonenkis. Informally, the capacity of a classification model is related to how complicated it can be. For example, consider the thresholding of a high-degree polynomial: if the polynomial evaluates above zero, that point is classified as positive, otherwise as negative. A high-degree polynomial can be wiggly, so that it can fit a given set of training points well. Such a polynomial has a high capacity. A much simpler alternative is to threshold a linear function. This function may not fit the training set well, because it has a low capacity. This notion of capacity is made rigorous below. == Definitions == === VC dimension of a set-family === Let C = { C } C ∈ C {\displaystyle {\mathcal {C}}=\{C\}_{C\in {\mathcal {C}}}} be a family of sets (also called set family, collection of sets or set of sets) and X {\displaystyle X} a set. Their intersection is defined as the following set family: C ∩ X := { C ∩ X ∣ C ∈ C } . {\displaystyle {\mathcal {C}}\cap X:=\{C\cap X\mid C\in {\mathcal {C}}\}.} Here typically X {\displaystyle X} and each C ∈ C {\displaystyle C\in {\mathcal {C}}} are subsets of a big "universe" of possibilities U {\displaystyle U} where intersection takes place. We say that a set X {\displaystyle X} is shattered by C {\displaystyle {\mathcal {C}}} if P ( X ) = C ∩ X {\displaystyle {\mathcal {P}}(X)={\mathcal {C}}\cap X} i.e. the set of intersections contains (hence is equal to) all the subsets of X {\displaystyle X} . For finite sets X {\displaystyle X} this is equivalent to | C ∩ X | = 2 | X | . {\displaystyle |{\mathcal {C}}\cap X|=2^{|X|}.} The VC dimension D {\displaystyle D} of C {\displaystyle {\mathcal {C}}} is the cardinality of the largest set that is shattered by C {\displaystyle {\mathcal {C}}} . If arbitrarily large sets can be shattered, the VC dimension of C {\displaystyle {\mathcal {C}}} is ∞ {\displaystyle \infty } . === VC dimension of a classification model === A binary classification model f {\displaystyle f} with some parameter vector θ {\displaystyle \theta } is said to shatter a set of generally positioned data points ( x 1 , x 2 , … , x n ) {\displaystyle (x_{1},x_{2},\ldots ,x_{n})} if, for every assignment of labels to those points, there exists a θ {\displaystyle \theta } such that the model f {\displaystyle f} makes no errors when evaluating that set of data points. The VC dimension of a model f {\displaystyle f} is the maximum number of points that can be arranged so that f {\displaystyle f} shatters them. More formally, it is the maximum cardinal D {\displaystyle D} such that there exists a generally positioned data point set of cardinality D {\displaystyle D} that can be shattered by f {\displaystyle f} . == Examples == f {\displaystyle f} is a constant classifier (with no parameters); Its VC dimension is 0 since it cannot shatter even a single point. In general, the VC dimension of a finite classification model, which can return at most 2 d {\displaystyle 2^{d}} different classifiers, is at most d {\displaystyle d} (this is an upper bound on the VC dimension; the Sauer–Shelah lemma gives a lower bound on the dimension). f {\displaystyle f} is a single-parametric threshold classifier on real numbers; i.e., for a certain threshold θ {\displaystyle \theta } , the classifier f θ {\displaystyle f_{\theta }} returns 1 if the input number is larger than θ {\displaystyle \theta } and 0 otherwise. The VC dimension of f {\displaystyle f} is 1 because: (a) It can shatter a single point. For every point x {\displaystyle x} , a classifier f θ {\displaystyle f_{\theta }} labels it as 0 if θ > x {\displaystyle \theta >x} and labels it as 1 if θ < x {\displaystyle \theta x + 2 {\displaystyle \theta >x+2} , as (1,0) if θ ∈ [ x − 4 , x − 2 ) {\displaystyle \theta \in [x-4,x-2)} , as (1,1) if θ ∈ [ x − 2 , x ] {\displaystyle \theta \in [x-2,x]} , and as (0,1) if θ ∈ ( x , x + 2 ] {\displaystyle \theta \in (x,x+2]} . (b) It cannot shatter any set of three points. For every set of three numbers, if the smallest and the largest are labeled 1, then the middle one must also be labeled 1, so not all labelings are possible. f {\displaystyle f} is a straight line as a classification model on points in a two-dimensional plane (this is the model used by a perceptron). The line should separate positive data points from negative data points. There exist sets of 3 points that can indeed be shattered using this model (any 3 points that are not collinear can be shattered). However, no set of 4 points can be shattered: by Radon's theorem, any four points can be partitioned into two subsets with intersecting convex hulls, so it is not possible to separate one of these two subsets from the other. Thus, the VC dimension of this particular classifier is 3. It is important to remember that while one can choose any arrangement of points, the arrangement of those points cannot change when attempting to shatter for some label assignment. Note, only 3 of the 23 = 8 possible label assignments are shown for the three points. f {\displaystyle f} is a single-parametric sine classifier, i.e., for a certain parameter θ {\displaystyle \theta } , the classifier f θ {\displaystyle f_{\theta }} returns 1 if the input number x {\displaystyle x} has sin ⁡ ( θ x ) > 0 {\displaystyle \sin(\theta x)>0} and 0 otherwise. The VC dimension of f {\displaystyle f} is infinite, since it can shatter any finite subset of the set { 2 − m ∣ m ∈ N } {\displaystyle \{2^{-m}\mid m\in \mathbb {N} \}} . == Uses == === In statistical learning theory === The VC dimension can predict a probabilistic upper bound on the test error of a classification model. Vapnik proved that the probability of the test error (i.e., risk with 0–1 loss function) distancing from an upper bound (on data that is drawn i.i.d. from the same distribution as the training set) is given by: Pr ( test error ⩽ training error + 1 N [ D ( log ⁡ ( 2 N D ) + 1 ) − log ⁡ ( η 4 ) ] ) = 1 − η , {\displaystyle \Pr \left({\text{test error}}\leqslant {\text{training error}}+{\sqrt {{\frac {1}{N}}\left[D\left(\log \left({\tfrac {2N}{D}}\right)+1\right)-\log \left({\tfrac {\eta }{4}}\right)\right]}}\,\right)=1-\eta ,} where D {\displaystyle D} is the VC dimension of the classification model, 0 < η ⩽ 1 {\displaystyle 0<\eta \leqslant 1} , and N {\displaystyle N} is the size of the training set (restriction: this formula is valid when D ≪ N {\displaystyle D\ll N} . When D {\displaystyle D} is larger, the test-error may be much higher than the training-error. This is due to overfitting). The VC dimension also appears in sample-complexity bounds. A space of binary functions with VC dimension D {\displaystyle D} can be learned with: N = Θ ( D + ln ⁡ 1 δ ε 2 ) {\displaystyle N=\Theta \left({\frac {D+\ln {1 \over \delta }}{\varepsilon ^{2}}}\right)} samples, where ε {\displaystyle \varepsilon } is the learning error and δ {\displaystyle \delta } is the failure probability. Thus, the sample-complexity is a linear function of the VC dimension of the hypothesis space. === In computational geometry === The VC dimension is one of the critical parameters in the size of ε-nets, which determines the complexity of approximation algorithms based on them; range sets without finite VC dimension may not have finite ε-nets at all. == Bounds == The VC dimension of the dual set-family of C {\displaystyle {\mathcal {C}}} is strictly less than 2 vc ⁡ ( C ) + 1 {\displaystyle 2^{\operatorname {vc} ({\mathcal {C}})+1}} , and this is best possible. The VC dimension of a finite set-family C {\displaystyle {\mathcal {C}}} is at most log 2 ⁡ | C | {\displaystyle \log _{2}|{\mathcal {C}}|} . This is because | C ∩ X | ≤ | X | {\displaystyle |{\mathcal {C}}\cap X|\leq |X|} by definition. Given a set-fa

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  Magiran

  Magiran (Persian: مگیران)—Iran's publications database—is a digital library that was founded in 2000 and includes digitized versions of scientific journals, which currently provides the possibility of searching among the full text of 1,500 journals. Registration is required for full access to the database, but access to some items such as newspapers is also possible without registration. A list of Iranian researchers is also maintained there.

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  Waffles (machine learning)

  Waffles is a collection of command-line tools for performing machine learning operations developed at Brigham Young University. These tools are written in C++, and are available under the GNU Lesser General Public License. == Description == The Waffles machine learning toolkit contains command-line tools for performing various operations related to machine learning, data mining, and predictive modeling. The primary focus of Waffles is to provide tools that are simple to use in scripted experiments or processes. For example, the supervised learning algorithms included in Waffles are all designed to support multi-dimensional labels, classification and regression, automatically impute missing values, and automatically apply necessary filters to transform the data to a type that the algorithm can support, such that arbitrary learning algorithms can be used with arbitrary data sets. Many other machine learning toolkits provide similar functionality, but require the user to explicitly configure data filters and transformations to make it compatible with a particular learning algorithm. The algorithms provided in Waffles also have the ability to automatically tune their own parameters (with the cost of additional computational overhead). Because Waffles is designed for script-ability, it deliberately avoids presenting its tools in a graphical environment. It does, however, include a graphical "wizard" tool that guides the user to generate a command that will perform a desired task. This wizard does not actually perform the operation, but requires the user to paste the command that it generates into a command terminal or a script. The idea motivating this design is to prevent the user from becoming "locked in" to a graphical interface. All of the Waffles tools are implemented as thin wrappers around functionality in a C++ class library. This makes it possible to convert scripted processes into native applications with minimal effort. Waffles was first released as an open source project in 2005. Since that time, it has been developed at Brigham Young University, with a new version having been released approximately every 6–9 months. Waffles is not an acronym—the toolkit was named after the food for historical reasons. == Advantages == Some of the advantages of Waffles in contrast with other popular open source machine learning toolkits include: Waffles automatically takes care of many issues related to data format in order to simplify its tools. Because it is implemented in C++, many of its algorithms are particularly fast. Also, the lack of dependency on any virtual machine makes it easier to deploy in conjunction with other applications. The functionality included in Waffles is very broad, including algorithms for dimensionality reduction, collaborative filtering, visualization, clustering, supervised learning, optimization, linear algebra, data transformation, image and signal processing, policy learning, and sparse matrix operations. == Disadvantages == Although Waffles provides significant breadth, it lacks the depth of many toolkits that focus on a particular area of machine learning. The Weka (machine learning) toolkit, for example, provides many more classification algorithms than Waffles provides. Waffles only has a limited graphical interface.

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  Language identification in the limit

  Language identification in the limit is a formal model for inductive inference of formal languages, mainly by computers (see machine learning and induction of regular languages). It was introduced by E. Mark Gold in a technical report and a journal article with the same title. In this model, a teacher provides to a learner some presentation (i.e. a sequence of strings) of some formal language. The learning is seen as an infinite process. Each time the learner reads an element of the presentation, it should provide a representation (e.g. a formal grammar) for the language. Gold defines that a learner can identify in the limit a class of languages if, given any presentation of any language in the class, the learner will produce only a finite number of wrong representations, and then stick with the correct representation. However, the learner need not be able to announce its correctness; and the teacher might present a counterexample to any representation arbitrarily long after. Gold defined two types of presentations: Text (positive information): an enumeration of all strings the language consists of. Complete presentation (positive and negative information): an enumeration of all possible strings, each with a label indicating if the string belongs to the language or not. == Learnability == This model is an early attempt to formally capture the notion of learnability. Gold's journal article introduces for contrast the stronger models Finite identification (where the learner has to announce correctness after a finite number of steps), and Fixed-time identification (where correctness has to be reached after an apriori-specified number of steps). A weaker formal model of learnability is the Probably approximately correct learning (PAC) model, introduced by Leslie Valiant in 1984. == Examples == It is instructive to look at concrete examples (in the tables) of learning sessions the definition of identification in the limit speaks about. A fictitious session to learn a regular language L over the alphabet {a,b} from text presentation:In each step, the teacher gives a string belonging to L, and the learner answers a guess for L, encoded as a regular expression. In step 3, the learner's guess is not consistent with the strings seen so far; in step 4, the teacher gives a string repeatedly. After step 6, the learner sticks to the regular expression (ab+ba). If this happens to be a description of the language L the teacher has in mind, it is said that the learner has learned that language.If a computer program for the learner's role would exist that was able to successfully learn each regular language, that class of languages would be identifiable in the limit. Gold has shown that this is not the case. A particular learning algorithm always guessing L to be just the union of all strings seen so far:If L is a finite language, the learner will eventually guess it correctly, however, without being able to tell when. Although the guess didn't change during step 3 to 6, the learner couldn't be sure to be correct.Gold has shown that the class of finite languages is identifiable in the limit, however, this class is neither finitely nor fixed-time identifiable. Learning from complete presentation by telling:In each step, the teacher gives a string and tells whether it belongs to L (green) or not (red, struck-out). Each possible string is eventually classified in this way by the teacher. Learning from complete presentation by request:The learner gives a query string, the teacher tells whether it belongs to L (yes) or not (no); the learner then gives a guess for L, followed by the next query string. In this example, the learner happens to query in each step just the same string as given by the teacher in example 3.In general, Gold has shown that each language class identifiable in the request-presentation setting is also identifiable in the telling-presentation setting, since the learner, instead of querying a string, just needs to wait until it is eventually given by the teacher. == Gold's theorem == More formally, a language L {\displaystyle L} is a nonempty set, and its elements are called sentences. a language family is a set of languages. a language-learning environment E {\displaystyle E} for a language L {\displaystyle L} is a stream of sentences from L {\displaystyle L} , such that each sentence in L {\displaystyle L} appears at least once. a language learner is a function f {\displaystyle f} that sends a list of sentences to a language. This is interpreted as saying that, after seeing sentences a 1 , a 2 . . . , a n {\displaystyle a_{1},a_{2}...,a_{n}} in that order, the language learner guesses that the language that produces the sentences should be f ( a 1 , . . . , a n ) {\displaystyle f(a_{1},...,a_{n})} . Note that the learner is not obliged to be correct — it could very well guess a language that does not even contain a 1 , . . . , a n {\displaystyle a_{1},...,a_{n}} . a language learner f {\displaystyle f} learns a language L {\displaystyle L} in environment E = ( a 1 , a 2 , . . . ) {\displaystyle E=(a_{1},a_{2},...)} if the learner always guesses L {\displaystyle L} after seeing enough examples from the environment. a language learner f {\displaystyle f} learns a language L {\displaystyle L} if it learns L {\displaystyle L} in any environment E {\displaystyle E} for L {\displaystyle L} . a language family is learnable if there exists a language learner that can learn all languages in the family. Notes: In the context of Gold's theorem, sentences need only be distinguishable. They need not be anything in particular, such as finite strings (as usual in formal linguistics). Learnability is not a concept for individual languages. Any individual language L {\displaystyle L} could be learned by a trivial learner that always guesses L {\displaystyle L} . Learnability is not a concept for individual learners. A language family is learnable if, and only if, there exists some learner that can learn the family. It does not matter how well the learner performs for learning languages outside the family. Gold's theorem is easily bypassed if negative examples are allowed. In particular, the language family { L 1 , L 2 , . . . , L ∞ } {\displaystyle \{L_{1},L_{2},...,L_{\infty }\}} can be learned by a learner that always guesses L ∞ {\displaystyle L_{\infty }} until it receives the first negative example ¬ a n {\displaystyle \neg a_{n}} , where a n ∈ L n + 1 ∖ L n {\displaystyle a_{n}\in L_{n+1}\setminus L_{n}} , at which point it always guesses L n {\displaystyle L_{n}} . == Learnability characterization == Dana Angluin gave the characterizations of learnability from text (positive information) in a 1980 paper. If a learner is required to be effective, then an indexed class of recursive languages is learnable in the limit if there is an effective procedure that uniformly enumerates tell-tales for each language in the class (Condition 1). It is not hard to see that if an ideal learner (i.e., an arbitrary function) is allowed, then an indexed class of languages is learnable in the limit if each language in the class has a tell-tale (Condition 2). == Language classes learnable in the limit == The table shows which language classes are identifiable in the limit in which learning model. On the right-hand side, each language class is a superclass of all lower classes. Each learning model (i.e. type of presentation) can identify in the limit all classes below it. In particular, the class of finite languages is identifiable in the limit by text presentation (cf. Example 2 above), while the class of regular languages is not. Pattern Languages, introduced by Dana Angluin in another 1980 paper, are also identifiable by normal text presentation; they are omitted in the table, since they are above the singleton and below the primitive recursive language class, but incomparable to the classes in between. == Sufficient conditions for learnability == Condition 1 in Angluin's paper is not always easy to verify. Therefore, people come up with various sufficient conditions for the learnability of a language class. See also Induction of regular languages for learnable subclasses of regular languages. === Finite thickness === A class of languages has finite thickness if every non-empty set of strings is contained in at most finitely many languages of the class. This is exactly Condition 3 in Angluin's paper. Angluin showed that if a class of recursive languages has finite thickness, then it is learnable in the limit. A class with finite thickness certainly satisfies MEF-condition and MFF-condition; in other words, finite thickness implies M-finite thickness. === Finite elasticity === A class of languages is said to have finite elasticity if for every infinite sequence of strings s 0 , s 1 , . . . {\displaystyle s_{0},s_{1},...} and every infinite sequence of languages in the class L 1 , L 2 , . . . {\displaystyle L_{1},L_{2},...} , there exists a finite number n such

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