Non-Personal Data (NPD) is electronic data that does not contain any information that can be used to identify a natural person. Thus, it can either be data that has no personal information to begin with (such as weather data, stock prices, data from anonymous IoT sensors); or it is data that had personal data that was subsequently pseudoanonymized (for example, identifiable strings substituted with random strings) or anonymized (such as by irreversibly removing all personal data). NPD is part of the overall Data Governance Strategy of a region or country. While personal data are covered by Data Protection Legislation such as GDPR, other kinds of data would fall under the scope of NPD Regulation. == Importance of non-personal data == It has been pointed out that the future is data-driven. What this means is that much of the present innovation taking place in domains such as Machine Learning and Artificial Intelligence is fueled by data, which is needed for calibrating the complex models (comprising neural network-based as well as other kinds). The larger the volume, diversity and quality of the data, the higher is the quality of the model, leading to better predictions and explanations. However, there is a flip-side to data availability. The newly-emerging awareness of privacy and the consequent need for powerful Data Protection Regulations (such as GDPR) makes it increasingly difficult or impossible to obtain data in the quantities required. This is a contradiction, and the only way out would be to remove all personal data from data sets (either by Data anonymization or Pseudonymization coupled with noise injection, at which point it becomes NPD. Therefore, many innovation-friendly countries are coming out with regulatory regimes that would ensure that personal data is protected, while, at the same time, non-personal data can be extracted from personal data so that innovation is fostered. In other words, NPD 'unlocks' value that was locked away in data sets that have personally-identifiable information. It is expected that multiple NPD data sets will begin to be available on free or commercial basis from different providers once the regulations are in place. == Emerging regulatory frameworks == Non-Personal Data has significant uses that may be economic, social, political or security-related. Several countries and regions are in the process of regulating the use of NPD. In May 2019, the European Union operationalized its Regulation of the Free Flow of NPD. India announced a nine-member expert committee to make recommendations on the regulation of NPD in 2019, which published its first report in mid-2020. The report was opened for public comments, after which it was revised and published in December 2020. == Proposed NPD regulatory framework in India == The following were the objectives of the proposed Indian regulation as per the revised report: Sovereignty: India has rights over the data of India, its people and organisations. Benefit India: Benefits of data must accrue to India and its people. Benefits the world: Innovation, new models and algorithms for the world. Privacy: Misuse, reidentification and harms must be prevented. Simplicity: The regulations should be simple, digital and unambiguous. Innovation and entrepreneurship: The data should be freely available for innovation and entrepreneurship in India. == Concerns == The major concern in the use of NPD is if there are techniques (statistical or AI-based) by which multiple data sets can be used to extract personally-identifiable data.
Projection-slice theorem
In mathematics, the projection-slice theorem, central slice theorem or Fourier slice theorem in two dimensions states that the results of the following two calculations are equal: Take a two-dimensional function f(r), project (e.g. using the Radon transform) it onto a (one-dimensional) line, and do a Fourier transform of that projection. Take that same function, but do a two-dimensional Fourier transform first, and then slice the function through its origin, parallel to the projection line. In operator terms, if F1 and F2 are the 1- and 2-dimensional Fourier transform operators mentioned above, P1 is the projection operator (which projects a 2-D function onto a 1-D line), S1 is a slice operator (which extracts a 1-D central slice from a function), then F 1 P 1 = S 1 F 2 . {\displaystyle F_{1}P_{1}=S_{1}F_{2}.} This idea can be extended to higher dimensions. This theorem is used, for example, in the analysis of medical CT scans where a "projection" is an x-ray image of an internal organ. The Fourier transforms of these images are seen to be slices through the Fourier transform of the 3-dimensional density of the internal organ, and these slices can be interpolated to build up a complete Fourier transform of that density. The inverse Fourier transform is then used to recover the 3-dimensional density of the object. This technique was first derived by Ronald N. Bracewell in 1956 for a radio-astronomy problem. == The projection-slice theorem in N dimensions == In N dimensions, the projection-slice theorem states that the Fourier transform of the projection of an N-dimensional function f(r) onto an m-dimensional linear submanifold is equal to an m-dimensional slice of the N-dimensional Fourier transform of that function consisting of an m-dimensional linear submanifold through the origin in the Fourier space which is parallel to the projection submanifold. In operator terms: F m P m = S m F N . {\displaystyle F_{m}P_{m}=S_{m}F_{N}.\,} == The generalized Fourier-slice theorem == In addition to generalizing to N dimensions, the projection-slice theorem can be further generalized with an arbitrary change of basis. For convenience of notation, we consider the change of basis to be represented as B, an N-by-N invertible matrix operating on N-dimensional column vectors. Then the generalized Fourier-slice theorem can be stated as F m P m B = S m B − T | B − T | F N {\displaystyle F_{m}P_{m}B=S_{m}{\frac {B^{-T}}{|B^{-T}|}}F_{N}} where B − T = ( B − 1 ) T {\displaystyle B^{-T}=(B^{-1})^{T}} is the transpose of the inverse of the change of basis transform. == Proof in two dimensions == The projection-slice theorem is easily proven for the case of two dimensions. Without loss of generality, we can take the projection line to be the x-axis. There is no loss of generality because if we use a shifted and rotated line, the law still applies. Using a shifted line (in y) gives the same projection and therefore the same 1D Fourier transform results. The rotated function is the Fourier pair of the rotated Fourier transform, for which the theorem again holds. If f(x, y) is a two-dimensional function, then the projection of f(x, y) onto the x axis is p(x) where p ( x ) = ∫ − ∞ ∞ f ( x , y ) d y . {\displaystyle p(x)=\int _{-\infty }^{\infty }f(x,y)\,dy.} The Fourier transform of f ( x , y ) {\displaystyle f(x,y)} is F ( k x , k y ) = ∫ − ∞ ∞ ∫ − ∞ ∞ f ( x , y ) e − 2 π i ( x k x + y k y ) d x d y . {\displaystyle F(k_{x},k_{y})=\int _{-\infty }^{\infty }\int _{-\infty }^{\infty }f(x,y)\,e^{-2\pi i(xk_{x}+yk_{y})}\,dxdy.} The slice is then s ( k x ) {\displaystyle s(k_{x})} s ( k x ) = F ( k x , 0 ) = ∫ − ∞ ∞ ∫ − ∞ ∞ f ( x , y ) e − 2 π i x k x d x d y {\displaystyle s(k_{x})=F(k_{x},0)=\int _{-\infty }^{\infty }\int _{-\infty }^{\infty }f(x,y)\,e^{-2\pi ixk_{x}}\,dxdy} = ∫ − ∞ ∞ [ ∫ − ∞ ∞ f ( x , y ) d y ] e − 2 π i x k x d x {\displaystyle =\int _{-\infty }^{\infty }\left[\int _{-\infty }^{\infty }f(x,y)\,dy\right]\,e^{-2\pi ixk_{x}}dx} = ∫ − ∞ ∞ p ( x ) e − 2 π i x k x d x {\displaystyle =\int _{-\infty }^{\infty }p(x)\,e^{-2\pi ixk_{x}}dx} which is just the Fourier transform of p(x). The proof for higher dimensions is easily generalized from the above example. == The FHA cycle == If the two-dimensional function f(r) is circularly symmetric, it may be represented as f(r), where r = |r|. In this case the projection onto any projection line will be the Abel transform of f(r). The two-dimensional Fourier transform of f(r) will be a circularly symmetric function given by the zeroth-order Hankel transform of f(r), which will therefore also represent any slice through the origin. The projection-slice theorem then states that the Fourier transform of the projection equals the slice or F 1 A 1 = H , {\displaystyle F_{1}A_{1}=H,} where A1 represents the Abel-transform operator, projecting a two-dimensional circularly symmetric function onto a one-dimensional line, F1 represents the 1-D Fourier-transform operator, and H represents the zeroth-order Hankel-transform operator. == Extension to fan beam or cone-beam CT == The projection-slice theorem is suitable for CT image reconstruction with parallel beam projections. It does not directly apply to fanbeam or conebeam CT. The theorem was extended to fan-beam and conebeam CT image reconstruction by Shuang-ren Zhao in 1995.
Actifsource
Actifsource is a domain-specific modeling workbench. It is realized as plug-in for the software development environment Eclipse. Actifsource supports the creation of multiple domain models which can be linked together. It comes with a UML-like graphical editor to create domain-specific languages and a general graphical editor to edit structures in the created languages. It supports code generation using user-defined generic code templates which are directly linked to the domain models. Code generation is integrated into Eclipse's incremental build process. == Interoperability == Actifsource can use models from other modelling tools by importing and exporting the ecore format which is defined by the Eclipse Modeling Framework. == Licensing policy == There are two versions of actifsource available: The free community edition which can be used freely for non-commercial projects and the enterprise edition which contains additional features. The enterprise edition comes with customer support and maintenance for a limited period of time. This package allows the customers to upgrade to new versions and maintenance releases during their support period.
Biopython
Biopython is an open-source collection of non-commercial Python modules for computational biology and bioinformatics. It makes robust and well-tested code easily accessible to researchers. Python is an object-oriented programming language and is a suitable choice for automation of common tasks. The availability of reusable libraries saves development time and lets researchers focus on addressing scientific questions. Biopython is constantly updated and maintained by a large team of volunteers across the globe. Biopython contains parsers for diverse bioinformatic sequence, alignment, and structure formats. Sequence formats include FASTA, FASTQ, GenBank, and EMBL. Alignment formats include Clustal, BLAST, PHYLIP, and NEXUS. Structural formats include the PDB, which contains the 3D atomic coordinates of the macromolecules. It has provisions to access information from biological databases like NCBI, Expasy, PBD, and BioSQL. This can be used in scripts or incorporated into their software. Biopython contains a standard sequence class, sequence alignment, and motif analysis tools. It also has clustering algorithms, a module for structural biology, and a module for phylogenetics analysis. == History == The development of Biopython began in 1999, and it was first released in July 2000. First "semi-complete" and "semi-stable" release was done in March 2001 and December 2002 respectively. It was developed during a similar time frame and with analogous goals to other projects that added bioinformatics capabilities to their respective programming languages, including BioPerl, BioRuby and BioJava. Early developers on the project included Jeff Chang, Andrew Dalke and Brad Chapman, though over 100 people have made contributions to date. In 2007, a similar Python project, namely PyCogent, was established. The initial scope of Biopython involved accessing, indexing and processing biological sequence files. The retrieved data from common biological databases will then be parsed into a python data structure. While this is still a major focus, over the following years added modules have extended its functionality to cover additional areas of biology. The key challenge in the design of parsers for bioinformatics file formats is the frequency at which the data formats change. This is due to inadequate curation of the structure of the data, and changes in the database contents. This problem is overcome by the application of a standard event-oriented parser design (see Key features and examples). As of version 1.77, Biopython no longer supports Python 2. The current stable release of Biopython version 1.85 was released on 15 January 2025. It only supports Python 3 and the recent releases of Biopython require NumPy (and not Numeric). == Design == Wherever possible, Biopython follows the conventions used by the Python programming language to make it easier for users familiar with Python. For example, Seq and SeqRecord objects can be manipulated via slicing, in a manner similar to Python's strings and lists. It is also designed to be functionally similar to other Bio projects, such as BioPerl. It is organized into modular sub-packages, e.g., Bio.Seq, Bio.Align, Bio.PDB, Bio.Entrez each of them useful in a different bioinformatics domain. It used principles, like encapsulation and polymorphism, notably in classes Seq, SeqRecord, and Bio.PDB.Structure. It can also interoperate with other Python tools (Pandas, Matplotlib and SciPy). Biopython can read and write most common file formats for each of its functional areas, and its license is permissive and compatible with most other software licenses, which allows Biopython to be used in a variety of software projects. == Requirements == Biopython is currently supported and tested with the following Python implementations: Python 3 or PyPy3 NumPy == Key features and examples == === Input and output === Biopython can read and write to a number of common formats. When reading files, descriptive information in the file is used to populate the members of Biopython classes, such as SeqRecord. This allows records of one file format to be converted into others. Very large sequence files can exceed a computer's memory resources, so Biopython provides various options for accessing records in large files. They can be loaded entirely into memory in Python data structures, such as lists or dictionaries, providing fast access at the cost of memory usage. Alternatively, the files can be read from disk as needed, with slower performance but lower memory requirements. === Sequences === A core concept in Biopython is the biological sequence, and this is represented by the Seq class. A Biopython Seq object is similar to a Python string in many respects: it supports the Python slice notation, can be concatenated with other sequences and is immutable. This object includes both general string-like and biological sequence-specific methods. It is best to store information about the biological type (DNA, RNA, protein) separately from the sequence, rather than using an explicit alphabet argument. === Sequence annotation === The SeqRecord class describes sequences, along with information such as name, description and features in the form of SeqFeature objects. Each SeqFeature object specifies the type of the feature and its location. Feature types can be ‘gene’, ‘CDS’ (coding sequence), ‘repeat_region’, ‘mobile_element’ or others, and the position of features in the sequence can be exact or approximate. === Accessing online databases === Through the Bio.Entrez module, users of Biopython can download biological data from NCBI databases. Each of the functions provided by the Entrez search engine is available through functions in this module, including searching for and downloading records. === Phylogeny === The Bio.Phylo module provides tools for working with and visualising phylogenetic trees. A variety of file formats are supported for reading and writing, including Newick, NEXUS and phyloXML. Common tree manipulations and traversals are supported via the Tree and Clade objects. Examples include converting and collating tree files, extracting subsets from a tree, changing a tree's root, and analysing branch features such as length or score. Rooted trees can be drawn in ASCII or using matplotlib (see Figure 1), and the Graphviz library can be used to create unrooted layouts (see Figure 2). === Genome diagrams === The GenomeDiagram module provides methods of visualising sequences within Biopython. Sequences can be drawn in a linear or circular form (see Figure 3), and many output formats are supported, including PDF and PNG. Diagrams are created by making tracks and then adding sequence features to those tracks. By looping over a sequence's features and using their attributes to decide if and how they are added to the diagram's tracks, one can exercise much control over the appearance of the final diagram. Cross-links can be drawn between different tracks, allowing one to compare multiple sequences in a single diagram. === Macromolecular structure === The Bio.PDB module can load molecular structures from PDB and mmCIF files, and was added to Biopython in 2003. The Structure object is central to this module, and it organises macromolecular structure in a hierarchical fashion: Structure objects contain Model objects which contain Chain objects which contain Residue objects which contain Atom objects. Disordered residues and atoms get their own classes, DisorderedResidue and DisorderedAtom, that describe their uncertain positions. Using Bio.PDB, one can navigate through individual components of a macromolecular structure file, such as examining each atom in a protein. Common analyses can be carried out, such as measuring distances or angles, comparing residues and calculating residue depth. === Population genetics === The Bio.PopGen module adds support to Biopython for Genepop, a software package for statistical analysis of population genetics. This allows for analyses of Hardy–Weinberg equilibrium, linkage disequilibrium and other features of a population's allele frequencies. This module can also carry out population genetic simulations using coalescent theory with the fastsimcoal2 program. === Wrappers for command line tools === Biopython previously included command-line wrappers for tools such as BLAST, Clustal, EMBOSS, and SAMtools. This option allowed users to run external tool commands from within the code using specialized Biopython classes. However, Bio.Application modules and their wrappers have deprecated and will be removed in future Biopython releases. The main reason for this is the high maintenance burden of updating them with the evolving external tools. The recommended approach is to directly construct and execute command-line tool commands using Python’s built-in subprocess module. This method provides flexibility and removes the dependency on the Biopython wrappers. subprocess is a native Python module useful for running ext
Software component
A software component is a modular unit of software that encapsulates specific functionality. The desired characteristics of a component are reusability and maintainability. == Value == Components allow software developers to assemble software with reliable parts rather than writing code for every aspect. It makes implementation more like factory assembly than custom building. == Attributes == Desirable attributes of a component include but are not limited to: Cohesive – encapsulates related functionality Reusable Robust Substitutable – can be replaced by another component with the same interface Documented Tested == Third-party == Some components are built in-house by the same organization or team building the software system. Some are third-party, developed elsewhere and assembled into the software system. == Component-based software engineering == For large-scale systems, component-based development encourages a disciplined process to manage complexity. == Framework == Some components conform to a framework technology that allows them to be consumed in a well-known way. Examples include: CORBA, COM, Enterprise JavaBeans, and the .NET Framework. == Modeling == Component design is often modeled visually. In Unified Modeling Language (UML) 2.0 a component is shown as a rectangle, and an interface is shown as a lollipop to indicate a provided interface and as a socket to indicate consumption of an interface. == History == The idea of reusable software components was promoted by Douglas McIlroy in his presentation at the NATO Software Engineering Conference of 1968. (One goal of that conference was to resolve the so-called software crisis of the time.) In the 1970s, McIlroy put this idea into practice with the addition of the pipeline feature to the Unix operating system. Brad Cox refined the concept of a software component in the 1980s. He attempted to create an infrastructure and market for reusable third-party components by inventing the Objective-C programming language. IBM introduced System Object Model (SOM) in the early 1990s. Microsoft introduced Component Object Model (COM) in the early 1990s. Microsoft built many domain-specific component technologies on COM, including Distributed Component Object Model (DCOM), Object Linking and Embedding (OLE), and ActiveX.
Perusall
Perusall is a social web annotation tool intended for use by students at schools and universities. It allows users to annotate the margins of a text in a virtual group setting that is similar to social media—with upvoting, emojis, chat functionality, and notification. It also includes automatic AI grading. == History == Perusall began as a research project at Harvard University. It later became an educational product for students and teachers. As of 2024, Perusall states more than 5 million students have used the tool at over 5,000 educational institutions in 112 countries." == Functionality == Perusall integrates with learning management systems such as Moodle, Canvas and Blackboard to aid with collaborative annotation. The tool supports annotation of a range of media including text, images, equations, videos, PDFs and snapshots of webpages.
Cryptee
Cryptee is a privacy focused client-side encrypted and cross-platform productivity suite and data storage service. == History == Cryptee was founded in 2017, by John Ozbay, a cybersecurity researcher, commenter, and activist, to exclusively focus on providing a secure document editing service similar to Google Docs and Photos for everyone, with a particular focus on victims and survivors of domestic abuse, journalists and reporters. == Software == Users can write personal documents, notes, journals, store images, videos, and various kinds of other files. The source code of Cryptee is open source and publicly available to allow anyone to audit the service with ease, and help identify errors or potential vulnerabilities in a public and transparent manner. Cryptee has a few key features that differentiate it from other services in the industry, such as its Ghost Folders and Ghost Albums features, built specifically with victims and survivors of domestic abuse, journalists and reporters in mind. Cryptee allows users to hide (ghost) folders for plausible deniability also as known as deniable encryption in the field of cryptography and steganography, and ensure privacy even under coercion. === Features === Cryptee Docs' features include: To-do lists, Markdown support, KaTeX math and file attachments. cross-platform accessible, as it is a progressive web app. Bulk transfer from other note taking apps such as Evernote. Encrypted PDF and print-accurate (A4 and U.S. Letter paper-sized) text editing. Ability to edit docx files Cryptee Photos' features include: Ability to create slideshows. Ability to store original quality of photos. Ability to tag photos for organization. === Commercial strategy === The company's commercial strategy is focused on offering to its users an open source and transparent Photo Storage, Document Editor and Cloud Storage services without trackers or advertisements as it seeks to compete with Google Docs, Google Photos and similar services through its offerings. === Privacy === Cryptee utilizes zero-access storage to safe-keep all users' sensitive digital belongings. == Advocacy == === Lockdown mode === In July 2022, to fortify iPhones against the Pegasus Spyware, Apple announced a new, upcoming Lockdown Mode feature in iOS 16, welcomed by many experts. In the following weeks after Apple's announcement, in August 2022, the Founder and CEO of Cryptee, and privacy activist John Ozbay published their research detailing shortcoming of Apple's Lockdown Mode. They demonstrated that enabling Lockdown Mode makes it possible for all websites and online ads to be able to detect if users have Lockdown Mode enabled or not. This was due to the fact that disabling web fonts (an attack surface) was detectable by websites. === Confrontations against Apple === ==== On PWAs ==== In February 2024, Apple announced plans to kill progressive web apps on iOS devices in the EU, claiming it was to comply with the Digital Markets Act (DMA). The announcement was criticized as anti-competitive by many in the tech industry, including by Tim Sweeney, the CEO of Epic Games. In response, Cryptee started working together with Open Web Advocacy (OWA), an international not-for-profit digital rights group to advocate for the future of the open web, promote web browser choice on mobile operating systems through challenging Apple's anti-competitive third party browser engine ban, and to champion the use and equality of progressive web apps over native apps, by reaching out to the European Union's Digital Markets Act (DMA) team. To better understand the consequences of Apple's decision to kill web apps, the EU announced that they "seek to investigate Apple over cutting off web apps", and that they sent "requests for information to Apple and to app developers, who can provide useful information for our assessment". Apart from sending a response to the EU, Cryptee, along with the OWA, launched an open letter to Tim Cook, which in 48 hours, got thousands of signatories including European Parliament Members Karen Melchior and Patrick Breyer; and thousands of other developers and organizations from over 100 countries. Consequently, 24 hours later, Apple backed off, and reversed course on its plan to cut off progressive web apps in the EU. ==== Ozbay's representations ==== Following the events, eventually on March 18, 2024, Founder and CEO of Cryptee John Ozbay represented the Open Web Advocacy group in European Union's Digital Markets Act (DMA) hearing for Apple. At the hearing, OWA confronted Apple, accused Apple of "maliciously intending to undermine user choice", and stated that there was no defense for Apple's behavior. In response, according to the tech news outlet Ars Technica, Apple's spokesperson "seemed to dodge Ozbay's question". ==== Cooperation with the EU ==== Within a week of the hearing, the European Union announced a DMA non-compliance investigation against Apple and United States' Department of Justice filed an antitrust lawsuit against Apple. A few months later, on June 27, 2024, Cryptee, in cooperation with EDRi — an international advocacy group, along with Article 19 — a British international human rights organization, Privacy International, F-Droid, Free Software Foundation Europe, Guardian Project and others have submitted a comprehensive analysis to the European Commission about how Apple's plans to comply with the Digital Markets Act are insufficient. == Reviews == In a 2018 article, Wall Street Journal's MarketWatch reviewed Cryptee, articulating the fact that Cryptee offers zero-access storage for photos, files, documents and notes, and pointed out that: "Being based in Estonia puts Cryptee outside the “14 eyes jurisdiction,” an international surveillance alliance of European Union and North American countries, making it less likely it will be targeted with demands for data". In addition, the review highlighted Cryptee's Ghost Folders feature which ensures privacy even under coercion. In a 2019 article, Reclaim The Net named Cryptee as one of the "5 great privacy-focused Evernote alternatives to keep your notes safe", underlining that: "When it comes to security, this app is state of the art." and that "When making this app, the developers thought about every aspect of security and have taken every precaution to make it as secure as possible.". The review further underscored Cryptee's open-source nature, its strong encryption, and easy migration features. In a 2021 article, The Verge reviewed Cryptee, pointing out that Cryptee, based out of Europe, is one of the main photo storage service alternatives to Google Photos, and that it's their recommendation for users who are "concerned about privacy and like the idea of encryption" as Cryptee "offers to keep all your photos encrypted using AES-256". In a 2024 article, Beebom, enlisted Cryptee as one of the "7 best iCloud Photos Alternatives for iPhone and iPad", complimenting Cryptee's simplicity, its use of encryption to safeguard users' photos against hacking by not storing any unencrypted data. The article also provided further attention to Cryptee's additional features such as such as Ghost Albums, slideshows, easy-to-use drag and drop uploads, tagging and users' ability to store original-quality photos on Cryptee, concluding that Cryptee is "a safe bet if you are on the lookout for a privacy-centric iCloud Photos alternative".