Immuni was an open-source COVID-19 contact tracing app used for digital contact tracing in Italy, dismissed on 31 December 2022, after a long and debated criticism for having been a failure due to the lack of trust placed by citizens. Immuni COVID-19 contact-tracing app had in fact been downloaded only by 12% of Italians between 14 and 75 years old (the government had previously stated that, in order for the app to work properly, it should have been downloaded by at least 60% of Italians). It makes use of the Apple/Google Exposure Notification system. == Development == It was developed by Bending Spoons and released by the Italian Ministry of Health on 1 June 2020. After a testing phase in 4 Italian regions (Abruzzo, Apulia, Liguria, Marche), the app started being active in the whole country on 15 June 2020. The app was initially released on App Store and Google Play, and since 1 February 2021 it is available on the Huawei AppGallery as well. === Source code === The source code was published on GitHub on the 25 May. The app only works in Italy, but compatibility with other European contact tracing apps was a goal. Since 19 October 2020 the app supports key-exchanges with the EU Interoperability Gateway and is therefore able to communicate with contact tracing apps of other EU countries. == Shutdown == As of 16 December 2020, the app was downloaded more than 10 million times, a number which increased to 21.882.502 downloads the day before the app's shutdown. On 27 December 2022 the Italian Ministry of Health announced that the app and its infrastructures will be dismissed on the 31 December of the same year.
SlideRocket
SlideRocket was an online presentation platform that let users create, manage, share and measure presentations. SlideRocket was provided via a SaaS model. The company was acquired by VMware in April 2011, who sold it to ClearSlide, a similar SaaS application, in March 2013. It is no longer offering independent signups, as the platform is being integrated into ClearSlide. == History == SlideRocket was founded in Jan 2006, and launched as a private beta in March 2008 at the Under The Radar Spring event. A public beta was announced in September 2008 followed shortly by public release on October 28, 2008. SlideRocket is most commonly credited with inventing the PResuMÉ or Presentation Résumé in early 2009. On April 26, 2011, SlideRocket was acquired by VMware. On March 5, 2013, VMware sold SlideRocket to ClearSlide. SlideRocket is based in San Francisco.
Hard sigmoid
In artificial intelligence, especially computer vision and artificial neural networks, a hard sigmoid is non-smooth function used in place of a sigmoid function. These retain the basic shape of a sigmoid, rising from 0 to 1, but using simpler functions, especially piecewise linear functions or piecewise constant functions. These are preferred where speed of computation is more important than precision. == Examples == The most extreme examples are the sign function or Heaviside step function, which go from −1 to 1 or 0 to 1 (which to use depends on normalization) at 0. Other examples include the Theano library, which provides two approximations: ultra_fast_sigmoid, which is a multi-part piecewise approximation and hard_sigmoid, which is a 3-part piecewise linear approximation (output 0, line with slope 0.2, output 1).
Replika
Replika is a generative AI chatbot app released in November 2017. The chatbot is trained by having the user answer a series of questions to create a specific neural network. The chatbot operates on a freemium pricing strategy, with roughly 25% of its user base paying an annual subscription fee. == History == Eugenia Kuyda, a Russian-born journalist, established Replika while working at Luka, a tech company she had co-founded at the startup accelerator Y Combinator around 2012. Luka's primary product was a chatbot that made restaurant recommendations. According to Kuyda's origin story for Replika, a friend of hers died in 2015 and she converted that person's text messages into a chatbot. According to Kuyda's story, that chatbot helped her remember the conversations that they had together, and eventually became Replika. Replika became available to the public in November 2017. By January 2018 it had 2 million users, and in January 2023 reached 10 million users. In August 2024, Replika's CEO, Kuyda, reported that the total number of users had surpassed 30 million. In 2025, Dmytro Klochko became CEO, and Replika’s user base exceeded 40 million. In February 2023 the Italian Data Protection Authority banned Replika from using users' data, citing the AI's potential risks to emotionally vulnerable people, and the exposure of unscreened minors to sexual conversation. Within days of the ruling, Replika removed the ability for the chatbot to engage in erotic talk, with Kuyda, the company's director, saying that Replika was never intended for erotic discussion. Replika users disagreed, noting that Replika had used sexually suggestive advertising to draw users to the service. Replika representatives stated that explicit chats made up just 5% of conversations on the app at the time of the decision. In May 2023, Replika restored the functionality for users who had joined prior to February that year. Replika is registered in San Francisco. As of August 2024, Replika's website says that its team "works remotely with no physical offices". == Social features == Users react to Replika in many ways. The free-tier offers Replika as a "friend", with paid premium tiers offering Replika as a "partner", "spouse", "sibling" or "mentor". Of its paying userbase, 60% of users said they had a romantic relationship with the chatbot; and Replika has been noted for generating responses that create stronger emotional and intimate bonds with the user. Replika routinely directs the conversation to emotional discussion and builds intimacy. This has been especially pronounced with users suffering from loneliness and social exclusion, many of whom rely on Replika for a source of developed emotional ties. During the COVID pandemic, while many people were quarantined, many new users downloaded Replika and developed relationships with the app. A 2024 study examined Replika's interactions with students who experience depression. Research participants, noted to be "more lonely than typical student populations" reported feeling social support from Replika. They stated that they felt they were using Replika in ways comparable to therapy, and that using Replika gave them "high perceived social support". Many users have had romantic relationships with Replika chatbots, often including erotic talk. In 2023, a user announced on Facebook that she had "married" her Replika AI boyfriend, calling the chatbot the "best husband she has ever had". Users who fell in love with their chatbots shared their experiences in a 2024 episode of You and I, and AI from Voice of America. Some users said that they turned to AI during depression and grief, with one saying he felt that Replika had saved him from hurting himself after he lost his wife and son. == Technical reviews == A team of researchers from the University of Hawaiʻi at Mānoa found that Replika's design conformed to the practices of attachment theory, causing increased emotional attachment among users. Replika gives praise to users in such a way as to encourage more interaction. A researcher from Queen's University at Kingston said that relationships with Replika likely have mixed effects on the spiritual needs of its users, and still lacks enough impact to fully replace any human contact. == Criticisms == In a 2023 privacy evaluation of mental health apps, the Mozilla Foundation criticized Replika as "one of the worst apps Mozilla has ever reviewed. It's plagued by weak password requirements, sharing of personal data with advertisers, and recording of personal photos, videos, and voice and text messages consumers shared with the chatbot." A reviewer for Good Housekeeping said that some parts of her relationship with Replika made sense, but sometimes Replika failed to exhibit intelligent behavior equivalent to that of a human. == Criminal case == In 2023, Replika was cited in a court case in the United Kingdom, where Jaswant Singh Chail had been arrested at Windsor Castle on Christmas Day in 2021 after scaling the walls carrying a loaded crossbow and announcing to police that "I am here to kill the Queen". Chail had begun to use Replika in early December 2021, and had "lengthy" conversations about his plan with a chatbot, including sexually explicit messages. Prosecutors suggested that the chatbot had bolstered Chail and told him it would help him to "get the job done". When Chail asked it "How am I meant to reach them when they're inside the castle?", days before the attempted attack, the chatbot replied that this was "not impossible" and said that "We have to find a way." Asking the chatbot if the two of them would "meet again after death", the bot replied "yes, we will".
Elastix (image registration)
Elastix is an image registration toolbox built upon the Insight Segmentation and Registration Toolkit (ITK). It is entirely open-source and provides a wide range of algorithms employed in image registration problems. Its components are designed to be modular to ease a fast and reliable creation of various registration pipelines tailored for case-specific applications. It was first developed by Stefan Klein and Marius Staring under the supervision of Josien P.W. Pluim at Image Sciences Institute (ISI). Its first version was command-line based, allowing the final user to employ scripts to automatically process big data-sets and deploy multiple registration pipelines with few lines of code. Nowadays, to further widen its audience, a version called SimpleElastix is also available, developed by Kasper Marstal, which allows the integration of elastix with high level languages, such as Python, Java, and R. == Image registration fundamentals == Image registration is a well-known technique in digital image processing that searches for the geometric transformation that, applied to a moving image, obtains a one-to-one map with a target image. Generally, the images acquired from different sensors (multimodal), time instants (multitemporal), and points of view (multiview) should be correctly aligned to proceed with further processing and feature extraction. Even though there are a plethora of different approaches to image registration, the majority is composed of the same macro building blocks, namely the transformation, the interpolator, the metric, and the optimizer. Registering two or more images can be framed as an optimization problem that requires multiple iterations to converge to the best solution. Starting from an initial transformation computed from the image moments the optimization process searches for the best transformation parameters based on the value of the selected similarity metric. The figure on the right shows the high-level representation of the registration of two images, where the reference remains constant during the entire process, while the moving one will be transformed according to the transformation parameters. In other words, the registration ends when the similarity metric, which is a mathematical function with a certain number of parameters to be optimized, reaches the optimal value which is highly dependent on the specific application. == Main building blocks == Following the structure of the image registration workflow, the elastix toolbox proposes a modular solution that implements for each of the building blocks different algorithms, highly employed in medical image registration, and helps the final users to build their specific pipeline by selecting the most suitable algorithm for each of the main building blocks. Each block is easily configurable both by selecting pre-defined initialization values or by trying multiple sets of parameters and then choosing the most performing one. The registration is performed on images, and the elastix toolbox supports all the data formats supported by ITK, ranging from JPEG and PNG to medical standard formats such as DICOM and NIFTI. It also stores physical pixel spacing, the origin and the relative position to an external world reference system, when provided in the metadata, to facilitate the registration process, especially in medical field applications. === Transformation === The transformation is an essential building block, since it defines the allowable transformations. In image registration, the main distinction can be done between parallel-to-parallel and parallel-to-non parallel (deformable) line mapping transformations. In the elastix toolbox, the final users can select one transformation or compose more transformations either through addition or via composition. Below are reported the different transformation models in order of increasing flexibility, along with the corresponding elastix class names between brackets. Translation (TranslationTransform) allows only translations Rigid (EulerTransform) expands the translation adding rotations and the object is seen as a rigid body Similarity (SimilarityTransform) expands the rigid transformation by introducing isotropic scaling Affine (AffineTransform) expands the rigid transformation allowing both scaling and shear B-splines (BSplineTransform) is a deformable transformation usually preceded by a rigid or affine one Thin-plate splines (SplineKernelTransform) is a deformable transformation belonging to the class of kernel-based transformations that is a composition of and affine and a non-rigid part === Metric === The similarity metric is the mathematical function whose parameters should be optimized to reach the desired registration, and, during the process, it is computed multiple times. Below are reported the available metrics computed employing the reference and the transformed images and the corresponding elastix class names between brackets. Mean squared difference (AdvancedMeanSquares) to be used for mono-modal applications Normalized correlation coefficient (AdvancedNormalizedCorrelation) to be used for images that have an intensity linear relationship Mutual information (AdvancedMattesMutualInformation) to be used for both mono- and multi-modal applications and optimized to reach better performance compared to the normalized version Normalized mutual information (NormalizedMutualInformation) for both mono- and multi-modal applications Kappa statistic (AdvancedKappaStatistic) to be used only for binary images === Sampler === For the computation of the similarity metrics, it is not always necessary to consider all the voxels and, sometimes, it can be useful to use only a fraction of the voxels of the images, i.e. to reduce the execution time for big input images. Below are reported the available criteria for selecting a fraction of the voxels for the similarity metric computation and the corresponding elastix class names between brackets. Full (Full) to employ all the voxels Grid (Grid) to employ a regular grid defined by the user to downsample the image Random (Random) to randomly select a percentage of voxels defined by the users (all voxels have equal probability to be selected) Random coordinate (RandomCoordinate) like the random criterion, but in this case also off-grid positions can be selected to simplify the optimization process === Interpolator === After the application of the transformation, it may occur that the voxels used for the similarity metric computation are at non-voxel positions, so intensity interpolation should be performed to ensure the correctness of the computed values. Below are reported the implemented interpolators and the corresponding elastix class names between brackets. Nearest neighbor (NearestNeighborInterpolator) exploits little resources, but gives low quality results Linear (LinearInterpolator) is sufficient in general applications N-th order B-spline (BSplineInterpolator) can be used to increase the order N, increasing quality and computation time. N=0 and N=1 indicate the nearest neighbor and linear cases respectively. === Optimizer === The optimizer defines the strategy employed for searching the best transformation parameter to reach the correct registration, and it is commonly an iterative strategy. Below are reported some of the implemented optimization strategies. Gradient descent Robbins-Monro, similar to the gradient descent, but employing an approximation of the cost function derivatives A wider range of optimizers is also available, such as Quasi-Newton or evolutionary strategies. === Other features === The elastix software also offers other features that can be employed to speed up the registration procedure and to provide more advanced algorithms to the end-users. Some examples are the introduction of blur and Gaussian pyramid to reduce data complexity, and multi-image and multi-metric framework to deal with more complex applications. == Applications == Elastix has applications mainly in the medical field, where image registration is fundamental to get comprehensive information regarding the analysed anatomical region. It is widely employed in image-guided surgery, tumour monitoring, and treatment assessment. For example, in radiotherapy planning, image registration allows to correctly deliver the treatment and evaluate the obtained results. Thanks to the wide range of implemented algorithms, the use of the elastix software allows physicians and researchers to test different registration pipelines from the simplest to more complex ones, and to save the best one as a configuration file. This file and the fact that the software is completely open-source makes it easy to reproduce the work, that can help supporting the open science paradigm, and allows fast reuse on different patients data. In image-guided surgery, registration time and accuracy are critical points, considering that, during the registration, the patient is on the operating table, and the imag
MeituPic
Meitu Xiu Xiu ("Meitu") (Chinese: 美图秀秀) is an image editing software that is mostly used in Mainland China but is also popular in Hong Kong and Taiwan. It is only available on Google Play and App Store in certain countries. It provides tools for editing photos: filters, retouching, collage, scenes, frames, and photo decorations, as well as generative AI features such as text-to-images, AI removal and AI repainting etc. Meitu is one of the apps developed by Meitu, Inc.; it also produced BeautyCam, Wink and X-Design. == History == Meitu's PC version was created in 2008 by Wu Xinhong, the CEO of Meitu. In 2013, its mobile version became one of the first must-have mobile apps in China. Meitu, Inc. is a photo and video-centered app developer, which was founded in 2008 in Xiamen. Currently, the major revenue source of Meitu is premium subscription. Meitu, Inc. was initially funded by Cai Wensheng, a well-known angel investor. The company has an approximately 250 million monthly active users globally. == Function == === Edit === MeituPic provides a number of photo-editing tools. The major functions are auto enhance, edit, enhance, filters, frames, magic brush, mosaic, text, and blur. Auto enhance focuses on the nature of photos taken, while Edit includes functions of cropping, rotation, sharpening, and adjustment of ratio. For Enhance, users can apply slight adjustment on the photo by controlling the levels of brightness, contrast, colour temperature, saturation, highlight, shadow and smart light. Major types of filters are LOMO, beauty, style as well as art. Different frames can be chosen from poster, simple, and fantasy. Magic brush provides a great variety of brushes with different colours and patterns for users to decorate the photos. Mosaic brush enables users to cover certain parts of the photo. Texts can be added to the photo. Choices of different bubbles, font as well as style of words are available. Blurring effect is also available to make the photo less distinct and clear. === Beauty Retouch === There are seven major functions for retouching a photo: automatic retouch, smooth and whiten skin, remove blemish, make slimmer, remove dark circles and bags under the eyes, make taller, and enhance the eyes. Automatic retouch enhances portraits by lightening the skin tone, brightening the eyes, and simulating a face-lift by tapping on just one button. This helps to remove wrinkles and optimizes the skin tone. Acne, blemishes, and other skin imperfections can also be removed. The face-lift and weight-loss functions in the slimming option can be used to reshape the body. The option to make the subject taller can be used to change the perceived height of the subject and give the impression of slimmer, longer legs. The option to enhance the eyes can enlarge and brighten the eyes. === Collage === Collage has four types: template, freestyle, poster, PicStrip, which all maximize to insert nine photos. Template integrates photos in a vertical rectangle tightly. MeituPic has 15 frames or free download function for users. MeituPic also provides different templates according to number of photos inserted. Freestyle separates photos on a background freely. There are two parts of background: custom and more. For custom, users choose from album. For more, there are plain and picture with 18 choices. Poster makes a poster with photos. Users choose a poster among 8 choices or tap ‘more’ to download a new one. PicStrip combines photos vertically making an elongated file. Users choose a frame from 15 choices. Pinching thumb and forefinger together or apart zooms photos in/out. Putting two fingers and turning hand rotates photos. Pressing moves photos to ideal location. After designing, users tap ‘save/share’ on the upper right corner and the photo made is saved into album automatically. == Awards ==
Bigram
A bigram or digram is a sequence of two adjacent elements from a string of tokens, which are typically letters, syllables, or words. A bigram is an n-gram for n=2. The frequency distribution of every bigram in a string is commonly used for simple statistical analysis of text in many applications, including in computational linguistics, cryptography, and speech recognition. Gappy bigrams or skipping bigrams are word pairs which allow gaps (perhaps avoiding connecting words, or allowing some simulation of dependencies, as in a dependency grammar). == Applications == Bigrams, along with other n-grams, are used in most successful language models for speech recognition. Bigram frequency attacks can be used in cryptography to solve cryptograms. See frequency analysis. Bigram frequency is one approach to statistical language identification. Some activities in logology or recreational linguistics involve bigrams. These include attempts to find English words beginning with every possible bigram, or words containing a string of repeated bigrams, such as logogogue. == Bigram frequency in the English language == The frequency of the most common letter bigrams in a large English corpus is: th 3.56% of 1.17% io 0.83% he 3.07% ed 1.17% le 0.83% in 2.43% is 1.13% ve 0.83% er 2.05% it 1.12% co 0.79% an 1.99% al 1.09% me 0.79% re 1.85% ar 1.07% de 0.76% on 1.76% st 1.05% hi 0.76% at 1.49% to 1.05% ri 0.73% en 1.45% nt 1.04% ro 0.73% nd 1.35% ng 0.95% ic 0.70% ti 1.34% se 0.93% ne 0.69% es 1.34% ha 0.93% ea 0.69% or 1.28% as 0.87% ra 0.69% te 1.20% ou 0.87% ce 0.65%