PauseAI is a global political movement founded in the Netherlands with the stated aim of achieving global coordination to stop the development of more powerful general artificial intelligence systems, at least until it is known how to build them safely, and keep them under democratic control. The movement was established in Utrecht in May 2023 by software entrepreneur Joep Meindertsma. == Proposal == PauseAI's stated goal is to "implement a temporary pause on the training of the most powerful general AI systems". Their website lists some proposed steps to achieve this goal: Set up an international AI safety agency, similar to the IAEA. Only allow training of general AI systems if their safety can be guaranteed. Only allow deployment of models after no dangerous capabilities are present. == Background == During the late 2010s and early 2020s, a rapid improvement in the capabilities of artificial intelligence models known as the AI boom was underway, which included the release of large language model GPT-3, its more powerful successor GPT-4, and image generation models Midjourney and DALL-E. This led to an increased concern about the risks of advanced AI, causing the Future of Life Institute to release an open letter calling for "all AI labs to immediately pause for at least six months the training of AI systems more powerful than GPT-4". The letter was signed by thousands of AI researchers and industry CEOs such as Yoshua Bengio, Stuart Russell, and Elon Musk. == History == Founder Joep Meindertsma first became worried about the existential risk from artificial intelligence after reading philosopher Nick Bostrom's 2014 book Superintelligence: Paths, Dangers, Strategies. He founded PauseAI in May 2023, putting his job as the CEO of a software firm on hold. Meindertsma claimed the rate of progress in AI alignment research is lagging behind the progress in AI capabilities, and said "there is a chance that we are facing extinction in a short frame of time". As such, he felt an urge to organise people to act. PauseAI's first public action was to protest in front of Microsoft's Brussels lobbying office in May 2023 during an event on artificial intelligence. In November of the same year, they protested outside the inaugural AI Safety Summit at Bletchley Park. The Bletchley Declaration that was signed at the summit, which acknowledged the potential for catastrophic risks stemming from AI, was perceived by Meindertsma to be a small first step. But, he argued "binding international treaties" are needed. He mentioned the Montreal Protocol and treaties banning blinding laser weapons as examples of previous successful global agreements. In February 2024, members of PauseAI gathered outside OpenAI's headquarters in San Francisco, in part due to OpenAI changing its usage policy that prohibited the use of its models for military purposes. On 13 May 2024, protests were held across thirteen countries before the AI Seoul Summit, including the United States, the United Kingdom, Brazil, Germany, Australia, and Norway. Meindertserma said that those attending the summit "need to realize that they are the only ones who have the power to stop this race". Protesters in San Francisco held signs reading "When in doubt, pause", and "Quit your job at OpenAI. Trust your conscience". Jan Leike, head of the "superalignment" team at OpenAI, resigned two days later due to his belief that "safety culture and processes [had] taken a backseat to shiny products".
Backend as a service
Backend as a service (BaaS), sometimes also referred to as mobile backend as a service (MBaaS), is a service for providing web app and mobile app developers with a way to easily build a backend to their frontend applications. Features available include user management, push notifications, and integration with social networking services. These services are provided via the use of custom software development kits (SDKs) and application programming interfaces (APIs). BaaS is a relatively recent development in cloud computing, with most BaaS startups dating from 2011 or later. Some of the most popular service providers are AWS Amplify and Firebase. == Purpose == Web and mobile apps require a similar set of features on the backend, including notification service, integration with social networks, and cloud storage. Each of these services has its own API that must be individually incorporated into an app, a process that can be time-consuming and complicated for app developers. BaaS providers form a bridge between the frontend of an application and various cloud-based backends via a unified API and SDK. Providing a consistent way to manage backend data means that developers do not need to redevelop their own backend for each of the services that their apps need to access, potentially saving both time and money. Although similar to other cloud-computing business models, such as serverless computing, software as a service (SaaS), infrastructure as a service (IaaS), and platform as a service (PaaS), BaaS is distinct from these other services in that it specifically addresses the cloud-computing needs of web and mobile app developers by providing a unified means of connecting their apps to cloud services. == Features == BaaS providers offer different set of features and backend tools. Some of the most common features include: Database management. Most BaaS solutions provide SQL and/or NoSQL database management services for applications. Developers can store their app data without deploying and managing databases themselves. BaaS usually provides client SDKs, REST and GraphQL APIs for the frontend to interact with databases. File storage. BaaS providers often offer storage solutions for media files, user uploads, and other binary data. Applications can upload, download, and delete files through provided SDKs and APIs. Authentication and authorization. Some BaaS offer authentication and authorization services that allow developers to easily manage app users. This includes user sign-up, login, password reset, social media login integration through OAuth, user group and permission management etc. Notification service. Some BaaS providers such as Firebase and AWS Amplify have notification services that can send custom emails to users and push native notifications on mobile platforms. This is especially useful for applications that need to send messages, alerts, and reminders. Cloud functions. Some BaaS allow developers to deploy and run serverless functions. The functions are usually stateless and can be triggered by various ways including HTTP requests, SDK invocation, background server events, and cloud scheduled executions. Different providers offer runtime support for different languages, some of the popular languages are JavaScript/TypeScript (Node.js, Deno), Python, Java/Kotlin. Cloud functions extend the potential and flexibility of BaaS by allowing developers to write custom functionalities for their apps, working in a way similar to a traditional REST API backend framework. Usage analytics. Analytics data about application usage is often included in BaaS. This allows developers to monitor user behaviors and make decisions correspondingly in marketing strategies and performance optimizations. UI design. Some BaaS providers, such as AWS Amplify and Backendless, offer user interface designing tools that help developers design the frontend UI of web and mobile apps. While this may be useful for small teams and individual developers, UI design assistance may not be conventional in BaaS as it goes beyond the scope of backend infrastructure. Real-Time. Real-time features in a BaaS platform ensure that data updates and synchronizations occur instantly across all clients, making changes immediately visible to users. This is crucial for applications like live chat and collaborative tools, using technologies like WebSockets to maintain continuous server-client connections. == Service providers == BaaS providers have a broad focus, providing SDKs and APIs that work for app development on multiple platforms with different technology stacks, such as JavaScript (for Web apps), Flutter, Java/Kotlin (for Android apps), Swift/Objective-C (for iOS/MacOS/WatchOS/TvOS apps), .NET (for Windows) and others. BaaS providers also come in different types, suiting developers of different needs. === Cloud-based BaaS === Most BaaS providers host backend platforms on their cloud servers. They also manage the infrastructure, security, and scalability of the platforms. Developers can access the backend services via a web interface or the provided APIs. Some examples of cloud-based BaaS include Firebase (hosted on Google Cloud Platform), AWS Amplify (hosted on Amazon Web Services), and Microsoft Azure Mobile Apps (hosted on Microsoft Azure). === Self-hosted BaaS === Self-hosted BaaS allow developers to host backend on their own servers, providing more flexibility and potential to customization compared to cloud-based BaaS, which often is more difficult to migrate from. However, developers are also in charge of managing the infrastructure, security, and scalability of their servers. === Mobile BaaS === Mobile backend as a service (MBaaS) is a type of BaaS specifically for applications deployed in mobile systems. While some references use MBaaS interchangeably for BaaS, BaaS can have a wider variety of support such as for web apps and desktop apps. == Business model == BaaS providers generate revenue from their services in various ways, often using a freemium model. Under this model, a client receives a certain number of free active users or API calls per month, and pays a fee for each user or call over this limit. Alternatively, clients can pay a set fee for a package which allows for a greater number of calls or active users per month. There are also flat fee plans that make the pricing more predictable. Some of the providers offer the unlimited API calls inside their free plan offerings. Another business model that has been used by a lot of BaaS providers is PAYG (pay as you go), which has a flexible cost based on developers' usage of database, storage, bandwidth, function calls, user numbers etc.
The Great Automatic Grammatizator
The Great Automatic Grammatizator (published in the U.S. as The Umbrella Man and Other Stories) is a posthumous 1998 collection of thirteen short stories written by British author Roald Dahl. The stories were selected for teenagers from Dahl's adult works. All the stories included were published elsewhere originally; their sources are noted below. The stories, with the exception of the war story "Katina", possess a deadpan, ironic, bizarre, or even macabre sense of humor. They generally end with unexpected plot twists. == Stories == "The Great Automatic Grammatizator" (from Someone Like You): A mechanically-minded man reasons that the rules of grammar are fixed by certain, almost mathematical principles. By exploiting this idea, he is able to create a mammoth machine that can write a prize-winning novel in roughly fifteen minutes. The story ends on a fearful note, as more and more of the world's writers are forced into licensing their names—and all hope of human creativity—to the machine. "Mrs. Bixby and the Colonel's Coat" (from Kiss Kiss): Mrs. Bixby cheats on her dentist husband with a rich, dashing colonel. When their relationship breaks off, the colonel offers Mrs. Bixby a gorgeous and expensive mink coat. In an attempt to explain the coat away, Mrs. Bixby sets up an elaborate trick with the help of a pawn shop—but her husband learns of the ruse and manages to turn the tables. "The Butler" (from More Tales of the Unexpected): An obnoxious and newly wealthy couple employs a butler and chef to impress dinner guests. The butler recommends that the husband buy expensive wines to please his guests, and the man slavishly follows the idea. The butler and the chef reap the rewards of this idea, while making fools of the "fashionable" couple. "Man from the South" (from Someone Like You): At a seaside resort in Jamaica, a strange old man makes a bet with an American man in his late teens. If the young man's cigarette lighter can spark ten times without fail, the American will win a brand-new Cadillac car—but failure means losing the little finger of his right hand. The high-tension wager ensues, and with only a few sparks left, a woman—who knows only too well the cost of the old man's bets—appears and stops the madness. "The Landlady" (from Kiss Kiss): A young man traveling to London on business stops at a bed and breakfast along the way, where a strange and slightly dotty landlady eagerly welcomes him. The eccentric nature of the house, and the news that only two other young men have ever stayed there, confuse and frighten the young man. In the end, the landlady—who indulges in the hobby of taxidermy—and the boy share a drink of tea that tastes of bitter almonds, and the landlady softly smiles at what may be her latest stuffing project. "Parson's Pleasure" (from Kiss Kiss): A man discovers an extremely rare piece of Chippendale furniture at the farm of some boorish ranchers. He desperately attempts to buy the piece cheap, in the hope of selling it at auction to earn a huge profit. He manages to buy the piece "for firewood", only for the ranchers to destroy it in an attempt to make it fit into his car. "The Umbrella Man" (from More Tales of the Unexpected): On a rainy day, a mother and daughter meet a gentlemanly old man on a street corner, who offers them a beautiful silk umbrella in exchange for a pound note. They trade, and the daughter notices that the "feeble" old man suddenly seems much sprier. They follow him, and discover that the gentleman is a con artist who visits various pubs, has a drink, and then steals another umbrella to continue the cycle. "Katina" (from Over to You: Ten Stories of Flyers and Flying): A group of RAF pilots stationed in Greece during World War II discover a hauntingly beautiful young girl, whose "family is beneath the rubble." She becomes their squadron's unofficial "mascot". In the end, her fragile life is taken as she stands defiantly against a rain of bullets from Nazi aircraft, shaking her fists at the heavens. "The Way Up to Heaven" (from Kiss Kiss): Mrs. Foster suffers from a chronic phobia of being late for appointments. Her husband enjoys the cruel sport of purposely delaying their activities, just to rile his wife. On the day when Mrs. Foster is due to fly to Paris to visit her grandchildren, her husband engages in his usual tricks. But as Mrs. Foster rushes from their taxi to the house to find him, she hears a strange noise—and turns triumphantly toward her cab. It is only when she returns, and calls a man to "repair the lift" that was stuck between floors in the house, that readers guess Mr. Foster's fate. "Royal Jelly" (from Kiss Kiss): New parents fear for the life of their little girl, who is sickly and dangerously underweight. The husband, a beekeeper, remembers hearing of the miraculous royal jelly used by bees to transform one particular larva into a queen. He adds the mixture to his daughter's bottles, and she puts on weight at an astonishing rate. The mother senses that something is amiss, and the husband confesses his actions—along with the fact that he himself swallowed buckets of the jelly for months in an attempt to cure his impotence. The royal jelly did the trick—but the strange side-effects include a disturbing metamorphosis for both father and daughter. "Vengeance is Mine Inc." (from More Tales of the Unexpected): Two brothers who are short of cash bemoan their fate over breakfast while reading the society column of a newspaper. They hit upon a scheme to take revenge on cruel tabloid writers in exchange for money from wealthy patrons. The unconventional plan works, and the brothers line their pockets with the spoils of their plans. "Taste" (from Someone Like You): A rich man with a beautiful young daughter hosts a dinner party, inviting a famous connoisseur of fine wines. When the rich man boasts that he has a wine that the expert cannot identify, the stakes become frighteningly high: if he can guess the name and vintage of the wine, he will win his daughter's hand. After an elaborate show, the expert guesses correctly; however, the family's maid appears and inadvertently exposes the guest as a cheat, thus saving the girl. "Neck" (from Someone Like You): A newspaper heir finds himself suddenly engaged to the voluptuous and controlling Lady Tutton. He loses all control of his life, and only his trusted butler and friends realize how broken he is by her control. A weekend trip to their estate, however, proves the perfect opportunity for Lord Tutton to engage in revenge against his wicked wife: her head is trapped in a valuable piece of wooden sculpture, and he must decide whether to use a saw or an axe to cut her free. == Publication details == Dahl, Roald (19 January 2004). The Umbrella Man and Other Stories. Speak. ISBN 9780142400876. == Reception == Groff Conklin in 1954 called the short story "The Great Automatic Grammatizator" "an awe-inspiring fantasy-satire ... an unforgettable bit of biting nonsense".
ICAART
The International Conference on Agents and Artificial Intelligence (ICAART) is a meeting point for researchers (among others) with interest in the areas of Agents and Artificial Intelligence. There are 2 tracks in ICAART, one related to Agents and Distributed AI in general and the other one focused in topics related to Intelligent Systems and Computational Intelligence. The conference program is composed of several different kind of sessions like technical sessions, poster sessions, keynote lectures, tutorials, special sessions, doctoral consortiums, panels and industrial tracks. The papers presented in the conference are made available at the SCITEPRESS digital library, published in the conference proceedings and some of the best papers are invited to a post-publication with Springer. ICAART's first edition was in 2009 counting with several keynote speakers like Marco Dorigo, Edward H. Shortliffe and Eduard Hovy. Since then, the conference had several other invited speakers like Katia Sycara, Nick Jennings, Robert Kowalski, Boi Faltings and Tim Finin. Bart Selman is one of the names confirmed for the next edition of this conference. Since 2012 the conference is held in conjunction with 2 other conferences: the International Conference on Operations Research and Enterprise Systems (ICORES) and the International Conference on Pattern Recognition Applications and Methods (ICPRAM). == Areas == === Agents === Agent communication languages Cooperation and Coordination Distributed Problem Solving Economic Agent Models Emotional Intelligence Group Decision Making Intelligent Auctions and Markets Mobile Agents Multi-agent systems Negotiation and Interaction Protocols Nep News Detection Agent Models and Architectures Physical Agents at Work Privacy, Safety and Security Programming Environments and Languages Robot and Multi-Robot Systems Self Organizing Systems Semantic Web Simulation Swarm Intelligence Task Planning and Execution Transparency and Ethical Issues Agent-Oriented Software Engineering Web Intelligence Agent Platforms and Interoperability Autonomous systems Cloud Computing and Its Impact Cognitive robotics Collective Intelligence Conversational Agents === Artificial intelligence === AI and Creativity Deep Learning Evolutionary Computing Fuzzy Systems Hybrid Intelligent Systems Industrial Applications of AI Intelligence and Cybersecurity Intelligent User Interfaces Knowledge Representation and Reasoning Knowledge-Based Systems Ambient Intelligence Machine learning Model-Based Reasoning Natural Language Processing Neural Networks Ontologies Planning and Scheduling Social Network Analysis Soft Computing State Space Search Bayesian Networks Uncertainty in AI Vision and Perception Visualization Big Data Case-Based Reasoning Cognitive Systems Constraint Satisfaction Data Mining Data Science == Editions == === ICAART 2023 – Lisbon, Portugal === === ICAART 2020 – Valletta, Malta === === ICAART 2019 – Prague, Czech Republic === Proceedings - Proceedings of the 11th International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-758-350-6 Proceedings - Proceedings of the 11th International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-758-350-6 === ICAART 2018 – Funchal, Madeira, Portugal === Proceedings - Proceedings of the 10th International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-758-275-2 Proceedings - Proceedings of the 10th International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-758-275-2 === ICAART 2017 – Porto, Portugal === Proceedings - Proceedings of the 9th International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-758-219-6 Proceedings - Proceedings of the 9th International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-758-220-2 === ICAART 2016 – Rome, Italy === Proceedings - Proceedings of the 8th International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-758-172-4 Proceedings - Proceedings of the 8th International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-758-172-4 === ICAART 2015 – Lisbon, Portugal === Proceedings - Proceedings of the 7th International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-758-073-4 Proceedings - Proceedings of the 7th International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-758-074-1 === ICAART 2014 – ESEO, Angers, Loire Valley, France === Proceedings - Proceedings of the 6th International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-758-015-4 Proceedings - Proceedings of the 6th International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-758-016-1 === ICAART 2013 – Barcelona, Spain === Proceedings - Proceedings of the 5th International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-8565-38-9 Proceedings - Proceedings of the 5th International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-8565-39-6 === ICAART 2012 – Vilamoura, Algarve, Portugal === Proceedings - Proceedings of the 4th International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-8425-95-9 Proceedings - Proceedings of the 4th International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-8425-96-6 === ICAART 2011 – Rome, Italy === Proceedings - Proceedings of the 3rd International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-8425-40-9 Proceedings - Proceedings of the 3rd International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-8425-41-6 === ICAART 2010 – Valencia, Spain === Proceedings - Proceedings of the 2nd International Conference on Web Information Systems and Technologies - Volume 1. ISBN 978-989-674-021-4 Proceedings - Proceedings of the 2nd International Conference on Web Information Systems and Technologies - Volume 2. ISBN 978-989-674-022-1 === ICAART 2009 – Porto, Portugal === Proceedings - Proceedings of the 1st International Conference on Web Information Systems and Technologies. ISBN 978-989-8111-66-1
Fuzzy mathematics
Fuzzy mathematics is a branch of mathematics that extends classical set theory and logic to model reasoning under uncertainty. Initiated by Lotfi Asker Zadeh in 1965 with the introduction of fuzzy sets, the field has since evolved to include fuzzy set theory, fuzzy logic, and various fuzzy analogues of traditional mathematic structures. Unlike classical mathematics, which usually relies on binary membership (an element either belongs to a set or it does not), fuzzy mathematics allows elements to partially belong to a set, with degrees of membership represented by values in the interval [0, 1]. This framework enables more flexible modeling of imprecise or vague concepts. Fuzzy mathematics has found applications in numerous domains, including control theory, artificial intelligence, decision theory, pattern recognition, and linguistics, where the modeling of gradations and uncertainty is essential. == Definition == A fuzzy subset A of a set X is defined by a function A: X → L, where L is typically the interval [0, 1]. This function is called the membership function of the fuzzy subset and assigns to each element x in X a degree of membership A(x) in the fuzzy set A. In classical set theory, a subset of X can be represented by an indicator function (also known as a characteristic function), which maps elements to either 0 or 1, indicating non-membership or full membership, respectively. Fuzzy subsets generalize this concept by allowing any real value between 0 and 1, thereby enabling partial membership. More generally, the codomain L of the membership function can be replaced with any complete lattice, resulting in the broader framework of L-fuzzy sets. == Fuzzification == The development of fuzzification in mathematics can be broadly divided into three historical stages: Initial, straightforward fuzzifications (1960s–1970s), Expansion of generalization techniques (1980s), Standardization, axiomatization, and L-fuzzification (1990s). Fuzzification generally involves extending classical mathematical concepts from binary (crisp) logic, where membership is determined by characteristic functions, to fuzzy logic, where membership is expressed by values in the interval [0, 1] via membership functions. Let A and B be fuzzy subsets of a set X. The fuzzy versions of set-theoretic operations are commonly defined as: ( A ∩ B ) ( x ) = min ( A ( x ) , B ( x ) ) {\displaystyle (A\cap B)(x)=\min(A(x),B(x))} ( A ∪ B ) ( x ) = max ( A ( x ) , B ( x ) ) {\displaystyle (A\cup B)(x)=\max(A(x),B(x))} for all x ∈ X {\displaystyle x\in X} . These operations can be generalized using t-norms and t-conorms, respectively. For example, the minimum operation can be replaced by multiplication: ( A ∩ B ) ( x ) = A ( x ) ⋅ B ( x ) {\displaystyle (A\cap B)(x)=A(x)\cdot B(x)} Fuzzification of algebraic structures often relies on generalizing the closure property. Let ∗ {\displaystyle } be a binary operation on X, and let A be a fuzzy subset of X. Then A is said to satisfy fuzzy closure if: A ( x ∗ y ) ≥ min ( A ( x ) , A ( y ) ) {\displaystyle A(xy)\geq \min(A(x),A(y))} for all x , y ∈ X {\displaystyle x,y\in X} . If ( G , ∗ ) {\displaystyle (G,)} is a group, then a fuzzy subset A of G is a fuzzy subgroup if: A ( x ∗ y − 1 ) ≥ min ( A ( x ) , A ( y − 1 ) ) {\displaystyle A(xy^{-1})\geq \min(A(x),A(y^{-1}))} for all x , y ∈ G {\displaystyle x,y\in G} . Similar generalizations apply to relational properties. For example, for example, for fuzzification of the transitivity property, a fuzzy relation R {\displaystyle R} on X {\displaystyle X} (i.e., a fuzzy subset of X × X {\displaystyle X\times X} ) is said to be fuzzy transitive if: R ( x , z ) ≥ min ( R ( x , y ) , R ( y , z ) ) {\displaystyle R(x,z)\geq \min(R(x,y),R(y,z))} for all x , y , z ∈ X {\displaystyle x,y,z\in X} . == Fuzzy analogues == Fuzzy subgroupoids and fuzzy subgroups were introduced in 1971 by A. Rosenfeld. Analogues of other mathematical subjects have been translated to fuzzy mathematics, such as fuzzy field theory and fuzzy Galois theory, fuzzy topology, fuzzy geometry, fuzzy orderings, and fuzzy graphs.
RFinder
RFinder ("repeater finder") is a subscription-based website and mobile app. RFinder's main service is the World Wide Repeater Directory (WWRD), which is a directory of amateur radio repeaters. RFinder is the official repeater directory of several amateur radio associations. RFinder has listings for several amateur radio modes, including FM, D-STAR, DMR, and ATV. == World Wide Repeater Directory == Repeaters are listed in the directory along with its call sign, Maidenhead Locator System and GPS coordinates, transmit/receive offset ("split"), CTCSS and DCS squelch settings, and VoIP settings (IRLP and Echolink nodes). The directory has over 50,000 repeater listings in over 170 countries. === Website === The RFinder website has several search options including for routes. === Forums === RFinder user forums is for help and support for the app and hardware. === Mobile app === RFinder has mobile apps for Android and iOS. When using the mobile app, RFinder can display the distance to repeaters, based on the mobile device's current location. === ARRL Repeater Directory === The ARRL publishes the ARRL Repeater Directory which contains over 31,000 repeater listings for the US and Canada with listings provided by RFinder. == Subscription == RFinder requires a subscription. A one-year subscription is US$12.99. == Radio programming software == Some radio programming software applications can query RFinder and download repeater listing to program radios. Compatible software includes: CHIRP RT Systems == Radio associations == RFinder is the official repeater directory of the following associations: Amateur Radio Society Italy American Radio Relay League Cayman Amateur Radio Society Deutscher Amateur Radio Club Federacion Mexicana de Radio Experimentadores L’association Réseau des Émetteurs Français Lietuvos Radijo Mėgėjų Draugija Liga de Amadores Brasilieros de Radio Emissão Radio Amateurs of Canada Radio Society of Great Britain Rede dos Emissores Portugueses Unión de Radioaficionados Españoles
Artificial intelligence in pharmacy
Artificial intelligence in pharmacy refers to the application of artificial intelligence (AI) techniques across pharmaceutical research and practice, including drug discovery, drug delivery, safety monitoring, clinical decision support, and pharmacy operations. Machine learning, deep learning, and natural language processing have been applied to tasks ranging from molecular design to patient adherence monitoring, with the aim of reducing development costs, improving accuracy, and personalizing treatment. Adoption has been uneven. Barriers include limited AI training among pharmacists, high infrastructure costs, and the risk of harm from models trained on unrepresentative data. Regulatory frameworks for AI-based pharmaceutical tools remain in active development across most jurisdictions. == Applications == === Drug discovery and development === Drug development is resource-intensive: bringing a single drug to market typically costs around $2.6 billion and takes 12–14 years. Machine learning algorithms have been applied to analyze molecular datasets to identify potential drug candidates, predict drug–target interactions, and optimize formulations. Artificial neural networks and generative adversarial networks have been used in drug discovery tasks including virtual screening, structure-activity relationship modeling, and de novo molecule generation. Peptides designed using AI methods have shown activity against multidrug-resistant bacteria, and transcriptomic data from human cell lines has been used to train deep learning models to classify drugs by therapeutic properties. Results in drug discovery have been mixed. AI models depend on the quality and diversity of their training data; those trained on narrow chemical libraries can fail to generalize to novel molecular scaffolds. The gap between high virtual screening hit rates and success in preclinical or clinical testing remains a persistent challenge, and the translation of computationally predicted candidates into approved drugs has been slower than early projections suggested. === Drug delivery systems === AI methods including neural networks, principal component analysis, and neuro-fuzzy logic have been applied to identifying biological targets for pharmaceuticals and analyzing genetic information relevant to drug design. Computational models can predict how a formulation will behave in biological systems, helping narrow the field before laboratory synthesis begins. Systems have been proposed that monitor patient response and adjust doses in real time based on individual physiology, with potential applications in chronic disease management. Research has also explored AI applications in targeted cancer treatments and oral vaccine delivery, areas where precise control over drug release kinetics is a design priority. === Drug safety === AI has been applied to predicting and detecting adverse drug reactions using techniques including knowledge graphs, logistic regression classifiers, and neural networks. A 2023 study developed a machine learning algorithm using knowledge graph analysis to classify known causes of adverse reactions. Natural language processing and deep learning models including long short-term memory (LSTM) networks have shown better performance than conventional methods for detecting opioid misuse, drawing on both structured data from electronic health records and unstructured sources such as clinical notes. AI-based pharmacovigilance systems can scan large volumes of electronic health records and social media for drug safety signals at a scale not feasible with manual review. Limitations include difficulty distinguishing drug-related adverse events from unrelated conditions in free-text data, and the need for validated benchmarks to measure model performance against existing safety monitoring standards. === Clinical decision support and personalized medicine === Machine learning systems trained on patient datasets can predict individual risk profiles, including potential allergies and drug–drug interactions, reducing the risk of harm in complex polypharmacy cases where the number of possible interactions exceeds what a clinician can readily assess. Personalized dosing models have been developed for drugs with narrow therapeutic windows — including anticoagulants and immunosuppressants — using patient-specific variables such as weight, renal function, and relevant genetic markers. Prospective clinical validation of these systems has lagged behind their technical development. Most published evaluations report performance on retrospective datasets, and the regulatory pathway for AI-based clinical decision support tools in pharmacy varies by jurisdiction. === Pharmacy operations and automation === Robotic and AI-driven systems have been applied to dispensing accuracy and pharmacy logistics. At the UCSF Medical Center, robotic technology produced 350,000 medication doses with no dispensing errors recorded. Robots such as TUG assist with preparing and transporting medications and laboratory samples within hospital settings. AI has also been applied to inventory management, with demand-forecasting systems predicting medicine requirements to reduce shortages and minimize waste from expired stock. In community pharmacy settings, AI tools have been used to flag potential prescription errors and alert pharmacists to drug–drug interactions before dispensing. === Medication adherence === Confirming that patients take prescribed medications as directed is a persistent challenge in healthcare. AI-enabled tools including smart pillboxes, RFID tags, ingestible sensors, and video check-ins have been applied to this problem. Smart pillboxes record when they are opened, providing real-time adherence data that can be reviewed remotely by care teams. Ingestible sensors transmit a signal after dissolution, offering direct confirmation of ingestion rather than proxy measures such as pill count or self-report. == Adoption challenges == === Barriers === Several barriers limit AI adoption in pharmacy practice. Many published evaluations report model performance on retrospective datasets rather than prospective clinical outcomes, making it difficult to assess real-world benefit. Pharmacists have reported limited AI training and knowledge, and research facilities often lack the computational infrastructure required for model development and validation. Models trained on biased or unrepresentative datasets can produce misleading results with direct patient safety consequences. === Regulatory frameworks === Regulatory frameworks for AI-based pharmaceutical tools are in active development. In the United States, the Food and Drug Administration (FDA) has issued guidance on AI and machine learning-based software as a medical device, addressing requirements for pre-market review and post-market performance monitoring. The European Medicines Agency has published discussion papers on the use of AI across the medicines development lifecycle, with particular attention to transparency in model training and validation. The absence of harmonized international standards creates compliance complexity for developers operating across multiple jurisdictions. === Ethical challenges === AI adoption raises data privacy and security concerns, including the risk of exposing sensitive patient information through data breaches. Algorithmic bias presents a related hazard: a model trained on an unrepresentative patient population may generate unsuitable treatment recommendations for patients not reflected in its training data, with potential for disparate outcomes across demographic groups. The opacity of some machine learning models, particularly deep neural networks, limits clinicians' ability to interpret or contest a recommendation, raising questions of accountability when a model-assisted decision results in patient harm. === Proposed solutions === Responses proposed in the literature include AI-focused education programs for pharmacists, increased public funding for healthcare AI research, encryption and governance frameworks for patient data, and regulatory requirements to prevent the use of biased training datasets. Greater transparency about training data provenance, model architecture, and validation methodology has also been recommended, including disclosure requirements in regulatory submissions. === Future directions === Research groups have called for tighter integration between AI systems and electronic health records to reduce healthcare costs and improve continuity of care across settings. International collaboration through shared AI frameworks and federated learning approaches has been proposed to address data scarcity in underrepresented patient populations and accelerate validation across institutions.