"The Life and Times of Multivac" is a science fiction short story by American writer Isaac Asimov. The story first appeared in the 5 January 1975 issue of The New York Times Magazine, and was reprinted in the collections The Bicentennial Man and Other Stories and The Best of Creative Computing in 1976. It is one of a loosely connected series of stories concerning a fictional supercomputer called Multivac. "The Life and Times of Multivac" was the first piece of fiction ever commissioned and published by The New York Times. Asimov's original title for the story was "Mathematical Games", but after the story appeared under the new title he decided he liked it. In his commentary on the story in The Bicentennial Man and Other Stories collection, Asimov stated, "More people came up to me over the next few weeks to tell me they had read that story than had ever been the case for any other story I had ever written." == Plot summary == When humanity begins to chafe under Multivac’s benevolent tyranny, one man takes matters into his own hands to destroy the great computer. By appearing to betray his fellow humans, he places himself in a position to permanently destroy Multivac. It is implied that it is not until completion of the act that he and his peers suddenly realize the enormity of their actions and the consequences it will have on humanity.
Super-resolution imaging
Super-resolution imaging (SR) is a class of techniques that improve the resolution of an imaging system. In optical SR the diffraction limit of systems is transcended, while in geometrical SR the resolution of digital imaging sensors is enhanced. In some radar and sonar imaging applications (e.g. magnetic resonance imaging (MRI), high-resolution computed tomography), subspace decomposition-based methods (e.g. MUSIC) and compressed sensing-based algorithms (e.g., SAMV) are employed to achieve SR over standard periodogram algorithm. Super-resolution imaging techniques are used in general image processing and in super-resolution microscopy. == Super-resolution principles == Several concepts are fundamental to super-resolution imaging: Diffraction limit: the capacity of an optical instrument to reproduce the details of an object in an image has limits that are imposed by laws of physics: the diffraction equations in the wave theory of light, or the uncertainty principle for photons in quantum mechanics. Information transfer can never be increased beyond this boundary, but packets outside the limits can be cleverly swapped for (or multiplexed with) some inside it. Super-resolution microscopy does not so much “break” as “circumvent” the diffraction limit. New procedures probing electro-magnetic disturbances at the molecular level (in the so-called near field) remain fully consistent with Maxwell's equations. Spatial frequency domain: A succinct expression of the diffraction limit is given in the spatial frequency domain. In Fourier optics light distributions are expressed as superpositions of a series of grating light patterns in a range of fringe widths - these widths represent the spatial frequencies. It is generally taught that diffraction theory stipulates an upper limit, the cut-off spatial-frequency, beyond which pattern elements fail to be transferred into the optical image, i.e., are not resolved. But in fact what is set by diffraction theory is the width of the passband, not a fixed upper limit. No laws of physics are broken when a spatial frequency band beyond the cut-off spatial frequency is swapped for one inside it: this has long been implemented in dark-field microscopy. Nor are information-theoretical rules broken when superimposing several bands, disentangling them in the received image needs assumptions of object invariance during multiple exposures, i.e., the substitution of one kind of uncertainty for another. Information: When the term super-resolution is used in techniques based on the inference of object details using a statistical treatment of the image within standard resolution limits (for example, averaging multiple exposures), it involves an exchange of one kind of information (extracting signal from noise) for another (the assumption that the target has remained invariant). Recent breakthroughs incorporate quantum-transformer hybrids into super-resolution, such as QUIET‑SR, a 2025 model that employs shifted quantum window attention within a transformer to enhance image detail while respecting diffraction and information-theory limits Similarly, frequency-integrated transformers (e.g., FIT) enrich super-resolution by explicitly combining spatial and frequency-domain information via FFT-based attention, improving reconstruction across scales Resolution and localization: True resolution involves the distinction of whether a target, e.g. a star or a spectral line, is single or double, ordinarily requiring separable peaks in the image. When a target is known to be single, its location can be determined with higher precision than the image width by finding the centroid (center of gravity) of its image light distribution. The word ultra-resolution had been proposed for this process but it did not catch on, and the high-precision localization procedure is typically referred to as super-resolution. == Techniques == === Optical or diffractive super-resolution === Substituting spatial-frequency bands: Though the bandwidth allowable by diffraction is fixed, it can be positioned anywhere in the spatial-frequency spectrum. Dark-field illumination in microscopy is an example. See also aperture synthesis. ==== Multiplexing spatial-frequency bands ==== An image is formed using the normal passband of the optical device. Then, some known light structure (for example, a set of light fringes) is superimposed on the target. The image now contains components resulting from the combination of the target and the superimposed light structure, e.g. moiré fringes, and carries information about target detail which simple unstructured illumination does not. The “superresolved” components, however, need disentangling to be revealed. For an example, see structured illumination (figure to left). ==== Multiple parameter use within traditional diffraction limit ==== If a target has no special polarization or wavelength properties, two polarization states or non-overlapping wavelength regions can be used to encode target details, one in a spatial-frequency band inside the cut-off limit the other beyond it. Both would use normal passband transmission but are then separately decoded to reconstitute target structure with extended resolution. ==== Probing near-field electromagnetic disturbance ==== Super-resolution microscopy is generally discussed within the realm of conventional optical imagery. However, modern technology allows the probing of electromagnetic disturbance within molecular distances of the source, which has superior resolution properties. See also evanescent waves and the development of the new super lens. === Geometrical or image-processing super-resolution === ==== Multi-exposure image noise reduction ==== When an image is degraded by noise, the resolution may be improved by averaging multiple exposures. See example on the right. ==== Single-frame deblurring ==== Known defects in a given imaging situation, such as defocus or aberrations, can sometimes be mitigated in whole or in part by suitable spatial-frequency filtering of even a single image. Such procedures all stay within the diffraction-mandated passband, and do not extend it. ==== Sub-pixel image localization ==== The location of a single source can be determined by computing the "center of gravity" (centroid) of the light distribution extending over several adjacent pixels (see figure on the left). Provided that there is enough light, this can be achieved with arbitrary precision, very much better than pixel width of the detecting apparatus and the resolution limit for the decision of whether the source is single or double. This technique, which requires the presupposition that all the light comes from a single source, is at the basis of what has become known as super-resolution microscopy, e.g. stochastic optical reconstruction microscopy (STORM), where fluorescent probes attached to molecules give nanoscale distance information. It is also the mechanism underlying visual hyperacuity. ==== Bayesian induction beyond traditional diffraction limit ==== Some object features, though beyond the diffraction limit, may be known to be associated with other object features that are within the limits and hence contained in the image. Then conclusions can be drawn, using statistical methods, from the available image data about the presence of the full object. The classical example is Toraldo di Francia's proposition of judging whether an image is that of a single or double star by determining whether its width exceeds the spread from a single star. This can be achieved at separations well below the classical resolution bounds, and requires the prior limitation to the choice "single or double?" The approach can take the form of extrapolating the image in the frequency domain, by assuming that the object is an analytic function, and that we can exactly know the function values in some interval. This method is severely limited by the ever-present noise in digital imaging systems, but it can work for radar, astronomy, microscopy or magnetic resonance imaging. More recently, a fast single image super-resolution algorithm based on a closed-form solution to ℓ 2 − ℓ 2 {\displaystyle \ell _{2}-\ell _{2}} problems has been proposed and demonstrated to accelerate most of the existing Bayesian super-resolution methods significantly. == Aliasing == Geometrical SR reconstruction algorithms are possible if and only if the input low resolution images have been under-sampled and therefore contain aliasing. Because of this aliasing, the high-frequency content of the desired reconstruction image is embedded in the low-frequency content of each of the observed images. Given a sufficient number of observation images, and if the set of observations vary in their phase (i.e. if the images of the scene are shifted by a sub-pixel amount), then the phase information can be used to separate the aliased high-frequency content from the true low-frequency content, and the full-resolution image can be accurate
Control-flow integrity
Control-flow integrity (CFI) is a general term for computer security techniques that prevent a wide variety of malware attacks from redirecting the flow of execution (the control flow) of a program. == Background == A computer program commonly changes its control flow to make decisions and use different parts of the code. Such transfers may be direct, in that the target address is written in the code itself, or indirect, in that the target address itself is a variable in memory or a CPU register. In a typical function call, the program performs a direct call, but returns to the caller function using the stack – an indirect backward-edge transfer. When a function pointer is called, such as from a virtual table, we say there is an indirect forward-edge transfer. Attackers seek to inject code into a program to make use of its privileges or to extract data from its memory space. Before executable code was commonly made read-only, an attacker could arbitrarily change the code as it is run, targeting direct transfers or even do with no transfers at all. After W^X became widespread, an attacker wants to instead redirect execution to a separate, unprotected area containing the code to be run, making use of indirect transfers: one could overwrite the virtual table for a forward-edge attack or change the call stack for a backward-edge attack (return-oriented programming). CFI is designed to protect indirect transfers from going to unintended locations. == Techniques == Associated techniques include code-pointer separation (CPS), code-pointer integrity (CPI), stack canaries, shadow stacks (SS), and vtable pointer verification. These protections can be classified into either coarse-grained or fine-grained based on the number of targets restricted. A coarse-grained forward-edge CFI implementation, could, for example, restrict the set of indirect call targets to any function that may be indirectly called in the program, while a fine-grained one would restrict each indirect call site to functions that have the same type as the function to be called. Similarly, for a backward edge scheme protecting returns, a coarse-grained implementation would only allow the procedure to return to a function of the same type (of which there could be many, especially for common prototypes), while a fine-grained one would enforce precise return matching (so it can return only to the function that called it). == Implementations == Related implementations are available in Clang (LLVM front-end),, GNU Compiler Collection, Microsoft's Control Flow Guard and Return Flow Guard, Google's Indirect Function-Call Checks and Reuse Attack Protector (RAP). === LLVM/Clang === The LLVM compiler's C/C++ front-end Clang provides a number of "CFI" schemes that works on the forward edge by checking for errors in virtual tables and type casts. Not all of the schemes are supported on all platforms and most of them, the exception being two "kcfi" schemes intended for low-level kernel software, depends on link-time optimization (LTO) to know what functions are supposed to be called in normal cases. Also provided is a separate "shadow call stack" (SCS) instrumentation pass that defends on the backward edge by checking for call stack modifications, available only for the aarch64 and RISC-V ISAs. And due to use of a shared processor register SCS is only enforceable on certain ABIs or if in other ways it is ensured that any other software using the register set (thread/processor) does not interfere with this use. Google has shipped Android with the Linux kernel compiled by Clang with link-time optimization (LTO) and CFI enabled since 2018. Even though SCS is available for the Linux kernel as an option, and support is also available for Android's system components it is recommended only to enable it for components for which it can be ensured that no third party code is loaded. === GCC === The GNU Compiler Collection implemented a "shadow call stack" compatible with Clang for aarch64 in v12 released in 2022. This feature is primarily intended for building the Linux kernel as support is missing from GCC user space libraries. === Intel Control-flow Enforcement Technology === Intel Control-flow Enforcement Technology (CET) detects compromises to control flow integrity with a shadow stack (SS) and indirect branch tracking (IBT). The kernel must map a region of memory for the shadow stack not writable to user space programs except by special instructions. The shadow stack stores a copy of the return address of each CALL. On a RET, the processor checks if the return address stored in the normal stack and shadow stack are equal. If the addresses are not equal, the processor generates an INT #21 (Control Flow Protection Fault). Indirect branch tracking detects indirect JMP or CALL instructions to unauthorized targets. It is implemented by adding a new internal state machine in the processor. The behavior of indirect JMP and CALL instructions is changed so that they switch the state machine from IDLE to WAIT_FOR_ENDBRANCH. In the WAIT_FOR_ENDBRANCH state, the next instruction to be executed is required to be the new ENDBRANCH instruction (ENDBR32 in 32-bit mode or ENDBR64 in 64-bit mode), which changes the internal state machine from WAIT_FOR_ENDBRANCH back to IDLE. Thus every authorized target of an indirect JMP or CALL must begin with ENDBRANCH. If the processor is in a WAIT_FOR_ENDBRANCH state (meaning, the previous instruction was an indirect JMP or CALL), and the next instruction is not an ENDBRANCH instruction, the processor generates an INT #21 (Control Flow Protection Fault). On processors not supporting CET indirect branch tracking, ENDBRANCH instructions are interpreted as NOPs and have no effect. === Microsoft Control Flow Guard === Control Flow Guard (CFG) was first released for Windows 8.1 Update 3 (KB3000850) in November 2014. Developers can add CFG to their programs by adding the /guard:cf linker flag before program linking in Visual Studio 2015 or newer. As of Windows 10 Creators Update (Windows 10 version 1703), the Windows kernel is compiled with CFG. The Windows kernel uses Hyper-V to prevent malicious kernel code from overwriting the CFG bitmap. CFG operates by creating a per-process bitmap, where a set bit indicates that the address is a valid destination. Before performing each indirect function call, the application checks if the destination address is in the bitmap. If the destination address is not in the bitmap, the program terminates. This makes it more difficult for an attacker to exploit a use-after-free by replacing an object's contents and then using an indirect function call to execute a payload. ==== Implementation details ==== For all protected indirect function calls, the _guard_check_icall function is called, which performs the following steps: Convert the target address to an offset and bit number in the bitmap. The highest 3 bytes are the byte offset in the bitmap The bit offset is a 5-bit value. The first four bits are the 4th through 8th low-order bits of the address. The 5th bit of the bit offset is set to 0 if the destination address is aligned with 0x10 (last four bits are 0), and 1 if it is not. Examine the target's address value in the bitmap If the target address is in the bitmap, return without an error. If the target address is not in the bitmap, terminate the program. ==== Bypass techniques ==== There are several generic techniques for bypassing CFG: Set the destination to code located in a non-CFG module loaded in the same process. Find an indirect call that was not protected by CFG (either CALL or JMP). Use a function call with a different number of arguments than the call is designed for, causing a stack misalignment, and code execution after the function returns (patched in Windows 10). Use a function call with the same number of arguments, but one of pointers passed is treated as an object and writes to a pointer-based offset, allowing overwriting a return address. Overwrite the function call used by the CFG to validate the address (patched in March 2015) Set the CFG bitmap to all 1's, allowing all indirect function calls Use a controlled-write primitive to overwrite an address on the stack (since the stack is not protected by CFG) === Microsoft eXtended Flow Guard === eXtended Flow Guard (XFG) has not been officially released yet, but is available in the Windows Insider preview and was publicly presented at Bluehat Shanghai in 2019. XFG extends CFG by validating function call signatures to ensure that indirect function calls are only to the subset of functions with the same signature. Function call signature validation is implemented by adding instructions to store the target function's hash in register r10 immediately prior to the indirect call and storing the calculated function hash in the memory immediately preceding the target address's code. When the indirect call is made, the XFG validation function compares the value in r10 to the target
Database
In computing, a database is an organized collection of data or a type of data store based on the use of a database management system (DBMS), the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an application associated with the database. Before digital storage and retrieval of data became widespread, index cards were used for data storage in a wide range of applications and environments: in the home to record and store recipes, shopping lists, contact information and other organizational data; in business to record presentation notes, project research and notes, and contact information; in schools as flash cards or other visual aids; and in academic research to hold data such as bibliographical citations or notes in a card file. Professional book indexers used index cards in the creation of book indexes until they were replaced by indexing software in the 1980s and 1990s. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases spans formal techniques and practical considerations, including data modeling, efficient data representation and storage, query languages, security and privacy of sensitive data, and distributed computing issues, including supporting concurrent access and fault tolerance. Computer scientists may classify database management systems according to the database models that they support. Relational databases became dominant in the 1980s. These model data as rows and columns in a series of tables, and the vast majority use SQL for writing and querying data. In the 2000s, non-relational databases became popular, collectively referred to as NoSQL, because they use different query languages. == Terminology and overview == Formally, a "database" refers to a set of related data accessed through the use of a "database management system" (DBMS), which is an integrated set of computer software that allows users to interact with one or more databases and provides access to all of the data contained in the database (although restrictions may exist that limit access to particular data). The DBMS provides various functions that allow entry, storage and retrieval of large quantities of information and provides ways to manage how that information is organized. Because of the close relationship between them, the term "database" is often used casually to refer to both a database and the DBMS used to manipulate it. Outside the world of professional information technology, the term database is often used to refer to any collection of related data (such as a spreadsheet or a card index) as size and usage requirements typically necessitate use of a database management system. Existing DBMSs provide various functions that allow management of a database and its data which can be classified into four main functional groups: Data definition – Creation, modification and removal of definitions that detail how the data is to be organized. Update – Insertion, modification, and deletion of the data itself. Retrieval – Selecting data according to specified criteria (e.g., a query, a position in a hierarchy, or a position in relation to other data) and providing that data either directly to the user, or making it available for further processing by the database itself or by other applications. The retrieved data may be made available in a more or less direct form without modification, as it is stored in the database, or in a new form obtained by altering it or combining it with existing data from the database. Administration – Registering and monitoring users, enforcing data security, monitoring performance, maintaining data integrity, dealing with concurrency control, and recovering information that has been corrupted by some event such as an unexpected system failure. Both a database and its DBMS conform to the principles of a particular database model. "Database system" refers collectively to the database model, database management system, and database. Physically, database servers are dedicated computers that hold the actual databases and run only the DBMS and related software. Database servers are usually multiprocessor computers, with generous memory and RAID disk arrays used for stable storage. Hardware database accelerators, connected to one or more servers via a high-speed channel, are also used in large-volume transaction processing environments. DBMSs are found at the heart of most database applications. DBMSs may be built around a custom multitasking kernel with built-in networking support, but modern DBMSs typically rely on a standard operating system to provide these functions. Since DBMSs comprise a significant market, computer and storage vendors often take into account DBMS requirements in their own development plans. Databases and DBMSs can be categorized according to the database model(s) that they support (such as relational or XML), the type(s) of computer they run on (from a server cluster to a mobile phone), the query language(s) used to access the database (such as SQL or XQuery), and their internal engineering, which affects performance, scalability, resilience, and security. == History == The sizes, capabilities, and performance of databases and their respective DBMSs have grown in orders of magnitude. These performance increases were enabled by the technology progress in the areas of processors, computer memory, computer storage, and computer networks. The concept of a database was made possible by the emergence of direct access storage media such as magnetic disks, which became widely available in the mid-1960s; earlier systems relied on sequential storage of data on magnetic tape. The subsequent development of database technology can be divided into three eras based on data model or structure: navigational, SQL/relational, and post-relational. The two main early navigational data models were the hierarchical model and the CODASYL model (network model). These were characterized by the use of pointers (often physical disk addresses) to follow relationships from one record to another. The relational model, first proposed in 1970 by Edgar F. Codd, departed from this tradition by insisting that applications should search for data by content, rather than by following links. The relational model employs sets of ledger-style tables, each used for a different type of entity. Only in the mid-1980s did computing hardware become powerful enough to allow the wide deployment of relational systems (DBMSs plus applications). By the early 1990s, however, relational systems dominated in all large-scale data processing applications, and as of 2018 they remain dominant: IBM Db2, Oracle, MySQL, and Microsoft SQL Server are the most searched DBMS. The dominant database language, standardized SQL for the relational model, has influenced database languages for other data models. Object databases were developed in the 1980s to overcome the inconvenience of object–relational impedance mismatch, which led to the coining of the term "post-relational" and also the development of hybrid object–relational databases. The next generation of post-relational databases in the late 2000s became known as NoSQL databases, introducing fast key–value stores and document-oriented databases. A competing "next generation" known as NewSQL databases attempted new implementations that retained the relational/SQL model while aiming to match the high performance of NoSQL compared to commercially available relational DBMSs. === 1960s, navigational DBMS === The introduction of the term database coincided with the availability of direct-access storage (disks and drums) from the mid-1960s onwards. The term represented a contrast with the tape-based systems of the past, allowing shared interactive use rather than daily batch processing. The Oxford English Dictionary cites a 1962 report by the System Development Corporation of California as the first to use the term "data-base" in a specific technical sense. As computers grew in speed and capability, a number of general-purpose database systems emerged; by the mid-1960s a number of such systems had come into commercial use. Interest in a standard began to grow, and Charles Bachman, author of one such product, the Integrated Data Store (IDS), founded the Database Task Group within CODASYL, the group responsible for the creation and standardization of COBOL. In 1971, the Database Task Group delivered their standard, which generally became known as the CODASYL approach, and soon a number of commercial products based on this approach entered the market. The CODASYL approach of
Space partitioning
In geometry, space partitioning is the process of dividing an entire space (usually a Euclidean space) into two or more disjoint subsets (see also partition of a set). In other words, space partitioning divides a space into non-overlapping regions. Any point in the space can then be identified to lie in exactly one of the regions. == Overview == Space-partitioning systems are often hierarchical, meaning that a space (or a region of space) is divided into several regions, and then the same space-partitioning system is recursively applied to each of the regions thus created. The regions can be organized into a tree, called a space-partitioning tree. Most space-partitioning systems use planes (or, in higher dimensions, hyperplanes) to divide space: points on one side of the plane form one region, and points on the other side form another. Points exactly on the plane are usually arbitrarily assigned to one or the other side. Recursively partitioning space using planes in this way produces a BSP tree, one of the most common forms of space partitioning. == Uses == === In computer graphics === Space partitioning is particularly important in computer graphics, especially heavily used in ray tracing, where it is frequently used to organize the objects in a virtual scene. A typical scene may contain millions of polygons. Performing a ray/polygon intersection test with each would be a very computationally expensive task. Storing objects in a space-partitioning data structure (k-d tree or BSP tree for example) makes it easy and fast to perform certain kinds of geometry queries—for example in determining whether a ray intersects an object, space partitioning can reduce the number of intersection test to just a few per primary ray, yielding a logarithmic time complexity with respect to the number of polygons. Space partitioning is also often used in scanline algorithms to eliminate the polygons out of the camera's viewing frustum, limiting the number of polygons processed by the pipeline. There is also a usage in collision detection: determining whether two objects are close to each other can be much faster using space partitioning. === In integrated circuit design === In integrated circuit design, an important step is design rule check. This step ensures that the completed design is manufacturable. The check involves rules that specify widths and spacings and other geometry patterns. A modern design can have billions of polygons that represent wires and transistors. Efficient checking relies heavily on geometry query. For example, a rule may specify that any polygon must be at least n nanometers from any other polygon. This is converted into a geometry query by enlarging a polygon by n/2 at all sides and query to find all intersecting polygons. === In probability and statistical learning theory === The number of components in a space partition plays a central role in some results in probability theory. See Growth function for more details. === In geography and GIS === There are many studies and applications where Geographical Spatial Reality is partitioned by hydrological criteria, administrative criteria, mathematical criteria or many others. In the context of cartography and GIS - Geographic Information System, is common to identify cells of the partition by standard codes. For example the for HUC code identifying hydrographical basins and sub-basins, ISO 3166-2 codes identifying countries and its subdivisions, or arbitrary DGGs - discrete global grids identifying quadrants or locations. == Data structures == Common space-partitioning systems include: BSP trees Quadtrees Octrees k-d trees Bins == Number of components == Suppose the n-dimensional Euclidean space is partitioned by r {\displaystyle r} hyperplanes that are ( n − 1 ) {\displaystyle (n-1)} -dimensional. What is the number of components in the partition? The largest number of components is attained when the hyperplanes are in general position, i.e, no two are parallel and no three have the same intersection. Denote this maximum number of components by C o m p ( n , r ) {\displaystyle Comp(n,r)} . Then, the following recurrence relation holds: C o m p ( n , r ) = C o m p ( n , r − 1 ) + C o m p ( n − 1 , r − 1 ) {\displaystyle Comp(n,r)=Comp(n,r-1)+Comp(n-1,r-1)} C o m p ( 0 , r ) = 1 {\displaystyle Comp(0,r)=1} - when there are no dimensions, there is a single point. C o m p ( n , 0 ) = 1 {\displaystyle Comp(n,0)=1} - when there are no hyperplanes, all the space is a single component. And its solution is: C o m p ( n , r ) = ∑ k = 0 n ( r k ) {\displaystyle Comp(n,r)=\sum _{k=0}^{n}{r \choose k}} if r ≥ n {\displaystyle r\geq n} C o m p ( n , r ) = 2 r {\displaystyle Comp(n,r)=2^{r}} if r ≤ n {\displaystyle r\leq n} (consider e.g. r {\displaystyle r} perpendicular hyperplanes; each additional hyperplane divides each existing component to 2). which is upper-bounded as: C o m p ( n , r ) ≤ r n + 1 {\displaystyle Comp(n,r)\leq r^{n}+1}
Automated dispensing cabinet
An automated dispensing cabinet (ADC), also called a unit-based cabinet (UBC), automated dispensing device (ADD), or automated dispensing machine (ADM)[1], is a computerized medicine cabinet for hospitals and healthcare settings. ADCs allow medications to be stored and dispensed near the point of care while controlling and tracking drug distribution. == Overview == Hospital pharmacies have provided medications for patients by filling patient-specific cassettes of unit-dose medications that were then delivered to the nursing unit and stored in medication cabinets or carts. ADCs, originally designed for hospital use, were introduced in hospitals in the 1980s and have facilitated the transition to alternative delivery models and more decentralized medication distribution systems.[2] Implementing automated dispensing cabinets as part of a decentralized or hybrid medication distribution system can improve patient safety and the accountability of the inventory, streamline certain billing processes. However, in the 2000s, the technology began to be deployed into other care settings where medication doses were stored onsite, and higher security methods were needed to control inventory, access, and dispensing of each patient dose. Settings that now deploy ADCs include long-term care facilities, hospice, critical access hospitals, surgery centers, group homes, residential care facilities, rehab and psych environments, animal health, dental clinics, and nursing education simulation. These diverse care settings share a common need to safely store, account for, and dispense individual doses of medications, especially narcotics and high-value medications, at the point of care.[3] ADCs track user access and dispensed medications, and their use can improve control over medication inventory. The real-time inventory reports generated by many cabinets can simplify the filling process and help the pharmacy track expired drugs. Furthermore, by restricting individual drugs – such as high-risk medications and controlled substances – to unique drawers within the cabinet, overall inventory management, patient safety, and medication security can be improved. Automated dispensing cabinets allow the pharmacy department to profile physician orders before they are dispensed.[4] ADCs can also enable providers to record medication charges upon dispensing, reducing the billing paperwork the pharmacy is responsible for. In addition, nurses can note returned medications using the cabinets' computers, enabling direct credits to patients' accounts. Since automated cabinets can be located on the nursing unit floor, nursing have speedier access to a patient's medications. Also, shorter waiting time ensures improved patient comfort and care.[5] == Role of automated dispensing in healthcare == Automated dispensing is a pharmacy practice in which a device dispenses medications and fills prescriptions. ADCs, which can handle many different medications, are available from a number of manufacturers such as BD, ARxIUM, and Omnicell. Though members of the pharmacy community have been utilizing automation technology since the 1980s, companies are constantly improving ADCs to meet changing needs and health standards in the industry. Several goals can be met by implementing an automated product in a healthcare facility. Patient safety can be ensured with the use of ADC technology such as barcoding. Anesthesia ADCs in operating rooms and perioperative areas may include label printing to prevent mix-ups such as errors between morphine and hydromorphone, two different opioid analgesics that frequently get confused. These systems also communicate with the pharmacy and its information management system to track medications removed and support inventory replenishment. == Key features == ADCs are like automated teller machines whose specific technologies such as barcode scanning and clinical decision support can improve medication safety. Some have metal locking drawers for added security and some have automated single-dose dispensing to prevent the need for a blind count each time a controlled substance is accessed. Over the years, ADCs have been adapted to facilitate compliance with emerging regulatory requirements such as pharmacy review of medication orders and safe practice recommendations. ADCs incorporate advanced software and electronic interfaces to synthesize high-risk steps in the medication use process. These unit-based medication repositories provide computer-controlled storage, dispensation, tracking, and documentation of medication distribution in the resident care unit. Since automated dispensing cabinets are not located in the pharmacy, they are considered "decentralized" medication distribution systems. Instead, they can be found at the point of care on the resident care unit. Tracking of the stocking and distribution process can occur by interfacing the unit with a central pharmacy computer. These cabinets can also be interfaced with other external databases such as resident profiles, the facility's admission/discharge/transfer system, and billing systems. Most ADC providers offer scalable systems since several important factors vary widely by facility such as budget, physical room size, patient population/demographics, type of healthcare facility, etc.
List of software palettes
This is a list of software palettes used by computers. Systems that use a 4-bit or 8-bit pixel depth can display up to 16 or 256 colors simultaneously. Many personal computers in the early 1990s displayed at most 256 different colors, freely selected by software (either by the user or by a program) from their wider hardware's RGB color palette. Usual selections of colors in limited subsets (generally 16 or 256) of the full palette includes some RGB level arrangements commonly used with the 8-bit palettes as master palettes or universal palettes (i.e., palettes for multipurpose uses). These are some representative software palettes, but any selection can be made in such of systems. For specific hardware color palettes, see the list of monochrome and RGB palettes, list of 8-bit computer hardware graphics, the list of 16-bit computer hardware graphics and the list of video game console palettes articles. Each palette is represented by an array of color patches. A one-pixel size version appears below each palette, to make it easy to compare palette sizes. For each unique palette, an image color test chart and sample image (truecolor original follows) rendered with that palette (without dithering) are given. The test chart shows the full 8-bit, 256 levels of the red, green, and blue (RGB) primary colors and cyan, magenta, and yellow complementary colors, along with a full 8-bit, 256 levels grayscale. Gradients of RGB intermediate colors (orange, lime green, sea green, sky blue, violet and fuchsia), and a full hue spectrum are also present. Color charts are not gamma corrected. These elements illustrate the color depth and distribution of the colors of any given palette, and the sample image indicates how the color selection of such palettes could represent real-life images. == System specifics == These are selections of colors officially employed as system palettes in some popular operating systems for personal computers that support 8-bit displays. === Microsoft Windows and IBM OS/2 default 16-color palette === Used by these platforms as a roughly backward compatible palette for the CGA, EGA and VGA text modes, but with colors arranged in a different order. Also, is the default palette for 16 color icons. The corresponding indices into this palette are: === Microsoft Windows default 20-color palette === In 256-color mode, there are four additional standard Windows colors, twenty system reserved colors in total; thus the system leaves 236 palette indexes free for applications to use. The system color entries inside a 256-color palette table are the first ten plus the last ten. In any case, the additional system colors do not seem to add a sharp color richness: they are only some intermediate shades of grayish colors. Since Windows 95, these additional colors can be changed by the system when a color scheme needs custom colors, reducing their utility as static, unchanging palette entries. The complete 20-color Windows system palette is: === Apple Macintosh default 16-color palette === When Apple Computer introduced the Macintosh II in 1987, this 16-color palette was included in System 4.1. === RISC OS default palette === Acorn RISC OS 2.x and 3.x provided this 16-color palette: === Solaris default 16-color palette === Solaris OS used this color palette: == RGB arrangements == These are selections of colors based in evenly ordered RGB levels which provide complete RGB combinations, mainly used as master palettes to display any kind of image within the limitations of the 8-bit pixel depth. === 6 level RGB === Having six levels for every primary, with 6³ = 216 combinations. The index can be addressed by (36×R)+(6×G)+B, with all R, G and B values in a range from 0 to 5. Intended as homogeneous RGB cube, it gives six true grays. Also, there is room for another sorts of 40 colors, so operating systems or programs can add extra colors. Systems that use this software palette are: Web-safe colors Apple Macintosh 256 color default palette. It also contains four gradients of ten shades each for gray, red, green and blue. === 6-7-6 levels RGB === This palette is constructed with six levels for red and blue primaries and seven levels for the green primary, giving 6×7×6 = 252 combinations. The index can be addressed by (42×R)+(6×G)+B, with R and B values in a range from 0 to 5 and G in a range from 0 to 6. The same case as the former, but with an added level of green due to the greater sensibility of the normal human eye to this frequency. It does not provide true grays, but remaining indexes can be filled with four intermediate grays. In any case, there is little room for any other color. === 6-8-5 levels RGB === This palette is constructed with six levels for red, eight levels for green and five levels for the blue primaries, giving 6×8×5 = 240 combinations. The index can be addressed by (40×R)+(5×G)+B, with R ranging from 0 to 5, G from 0 to 7 and B from 0 to 4. Levels are chosen in function of sensibility of the normal human eye to every primary color. Also, it does not provide true grays. Remaining indexes can be filled with sixteen intermediate grays or other fixed colors. In fact, this is the best balanced RGB master software palette, in a compromise between the RGB arrangement based in the human eye's sensibility and a sufficient remaining palette entries for another purposes. === 8-8-4 levels RGB === The 8-8-4 level RGB use eight levels for each of the red and green color components (3+3 high order bits), and four levels (2 low order bits) for the blue component, due to the lesser sensitivity of the normal human eye to this primary color. This results in an 8×8×4 = 256-color palette as follows: This RGB software palette occupies the full 8-bit range of possible palette entries, so there is no room for other fixed colors. Software using this palette must draw their user interface elements with the same colors used to show pictures. Also again, it does not provide true grays. == Other common uses of software palettes == === Grayscale palettes === Simple palette made doing every triplet RGB primaries having equal values as a continuous gradient from black to white through the full available palette entries. Here is the 8-bit, 256 levels palette: Used to display pure grayscale TIFF or JPEG images, for example. === Color gradient palettes === Palettes made of a continuous color gradient from darkest to lightest arbitrary hues. The pixel data is treated as if it were grayscale, but the color table plays with RGB color combinations, not only gray. The relationship between the original luminance and the mapped one can vary, but the lighting scale is preserved along all the palette entries. One very common case of such palettes is the sepia tone palette, which gives an image an old fashioned and aged look (left). Another gradient example, based on blue hues, is presented here (right), but any hue or mixing of hues can be used. Many cell phones with built-in cameras have options to take colorized photos using this technique. === Adaptive palettes === Those whose whole number of available indexes are filled with RGB combinations selected from the statistical order of appearance (usually balanced) of a concrete full true color original image. There exist many algorithms to pick the colors through color quantization; one well known is the Heckbert's median-cut algorithm. Here is the 8-bit, 256 color palette used with the color test chart and the image sample above: Adaptive palettes only work well with a unique image. Trying to display different images with adaptive palettes over an 8-bit display usually results in only one image with correct colors, because the images have different palettes and only one can be displayed at a time. Here is an example of what happens when an indexed color image is displayed with any color palette that is not its own adaptive palette: === False color palettes === Arbitrary gradient color scales, usually 256 shades, with no relationship with real colors of a given image. They are employed to artificially colorize a grayscale image to reveal details and/or to map the pixel level values to amounts of some physical magnitude (potential, temperature, altitude, etc.) Note, in the example above, that new details can be seen as blue over magenta in the background's dark areas of the original photograph. Here is the 8-bit, 256 color gradient palette used with the color test chart and the image sample above: There exist many false color palettes, some of them standardized, used mainly in scientific applications: astronomy and radioastronomy, satellite land imaging, thermography, study of materials, tomography and magnetic resonance imaging in medicine, etc.