geWorkbench (genomics Workbench) is an open-source software platform for integrated genomic data analysis. It is a desktop application written in the programming language Java. geWorkbench uses a component architecture. As of 2016, there are more than 70 plug-ins available, providing for the visualization and analysis of gene expression, sequence, and structure data. geWorkbench is the Bioinformatics platform of MAGNet, the National Center for the Multi-scale Analysis of Genomic and Cellular Networks, one of the 8 National Centers for Biomedical Computing funded through the NIH Roadmap (NIH Common Fund). Many systems and structure biology tools developed by MAGNet investigators are available as geWorkbench plugins. == Features == Computational analysis tools such as t-test, hierarchical clustering, self-organizing maps, regulatory network reconstruction, BLAST searches, pattern-motif discovery, protein structure prediction, structure-based protein annotation, etc. Visualization of gene expression (heatmaps, volcano plot), molecular interaction networks (through Cytoscape), protein sequence and protein structure data (e.g., MarkUs). Integration of gene and pathway annotation information from curated sources as well as through Gene Ontology enrichment analysis. Component integration through platform management of inputs and outputs. Among data that can be shared between components are expression datasets, interaction networks, sample and marker (gene) sets and sequences. Dataset history tracking - complete record of data sets used and input settings. Integration with 3rd party tools such as GenePattern, Cytoscape, and Genomespace. Demonstrations of each feature described can be found at GeWorkbench-web Tutorials. == Versions == geWorkbench is open-source software that can be downloaded and installed locally. A zip file of the released version Java source is also available. Prepackaged installer versions also exist for Windows, Macintosh, and Linux.
Trigger list
Trigger list in its most general meaning refers to a list whose items are used to initiate ("trigger") certain actions. == United States: Private financial information == In the United States, when a person applies for a mortgage loan, the lender makes a credit inquiry about the potential borrower from the national credit bureaus, Equifax, Experian and TransUnion. Unless the borrower is opted out, the credit bureaus put the applicants onto a "trigger list" of "leads" about persons who are interested in new loans. These lists are sold to numerous lenders all over the United States, and soon after the application the applicant starts receiving offers from all parts of the country. The trigger lists contain a significant amount of personal financial information. Among the buyers of trigger lists are "lead generators" which resell filtered information to borrowers, e.g., of people who live in a certain area and have a certain credit score. While the Federal Trade Commission considers the market of "trigger lists" to be a legal business, many people and organizations (such as the National Association of Mortgage Brokers) consider this a serious breach of privacy and lobby for putting this practice under regulatory controls. As of now, American consumers may opt-out from "trigger lists" by calling 1-888-5-OPTOUT (1-888-567-8688). == Nuclear non-proliferation == The Zangger Committee and the Nuclear Suppliers Group maintain lists of items that may contribute to nuclear proliferation; The nuclear non-proliferation treaty forbids its members to export such items to non-treaty members. these items are said to trigger the countries' responsibilities under the NPT, hence the name.
Sanctuary (app)
Sanctuary is a mobile app focusing on astrology and mystical services. Users enter their birthday, time of birth, and place of birth information into the app and receive a birth chart as well as daily horoscope readings. Users can also sign up for a monthly membership and receive on-demand astrological readings via a text message format. The service has been described as being “Talkspace for astrology" and "Uber for astrological readings". The mobile app uses an A.I.-driven interface. On May 14, 2019, Apple featured Sanctuary as the App of the Day. == History == Sanctuary initially began as project within the incubator of Lorne Michaels’ Broadway Video Ventures. The app officially launched on March 21, 2019. Its backers include Broadway Video Ventures, Greycroft Partners, and Shari Redstone.
Common Image Generator Interface
The Common Image Generator Interface (CIGI) (pronounced sig-ee), is an on-the-wire data protocol that allows communication between an Image Generator and its host simulation. The interface is designed to promote a standard way for a host device to communicate with an image generator (IG) within the industry. CIGI enables plug-and-play by standard-compliant image generator vendors and reduces integration costs when upgrading visual systems. == Background == Most high-end simulators do not have everything running on a single machine the way popular home software flight simulators are currently implemented. The airplane model is run on one machine, normally referred to as the host, and the out the window visuals or scene graph program is run on another, usually referred to as an Image Generator (IG). Frequently there are multiple IGs required to display the surrounding environment created by a host. CIGI is the interface between the 'host' and the IGs. The main goal of CIGI is to capitalize on previous investments through the use of a common interface. CIGI is designed to assist suppliers and integrators of IG systems with ease of integration, code reuse, and overall cost reduction. In the past most image generators provided their own proprietary interface; every host had to implement that interface making changing image generators a costly ordeal. CIGI was created to standardize the interface between the host and the image generator so that little modification would be needed to switch image generators. The CIGI initiative was largely spearheaded by The Boeing Company during the early 21st century. The latest version of CIGI (CIGI 4.0) was developed by the Simulation Interoperability Standards Organization (SISO) in the form of SISO-STD-013-2014, Standard for Common Image Generator Interface (CIGI), Version 4.0, dated 22 August 2014. SISO-STD-013-2014 is freely available from SISO. == Definitions == Image generator – In this context an image generator consists of one or more rendering channels that produce an image that can be used to visualize an “Out-The-Window” scene, or images produced by various sensor simulations such as Infra-red, Day TV, electro-optical, and night vision. Host simulation – In this context a “Host” is the computational system that provides information about the device being simulated so that the image generator can portray the correct scenery to the user. This information is passed via CIGI to the image generator. == Maturation == CIGI 4 is the latest version of the standard as was approved by the Simulation Interoperability Standards Organization on August 22, 2014. CIGI became an international SISO standard known as SISO-STD-013-2014; which contains the CIGI version 4.0 Interface Control Document (ICD). CIGI 4.0 is the official standard, published by SISO. Previous versions of CIGI were spearheaded by Boeing include CIGI v3.3, in November 2008, v3.2 April 2006, v3.1 June 2004, v3 November 2003, v2 in March 2002, and the original (v1) in March 2001 == Protocol dependencies == Typically, CIGI uses UDP as its transport protocol, but CIGI does not require a specific transport mechanism, only packet definition conformance. CIGI traffic does not have a well known port; however, the use of ports 8004-8005 has been widely adopted by commercial image generator vendors implementations. == Development tools == === Host Emulator === The Host Emulator can be used as a surrogate to manipulate the interface when a simulation Host is not available. It is a Windows-based image generator Host application used to develop, integrate and test image generators that use the CIGI protocol. It provides a graphical user interface (GUI) for the creation, modification and deletion of entities; manipulation of views; control of environmental attributes and phenomena; and other host functions. The Host Emulator has several features that are useful for integration and testing. A free-flight mode allows for fixed-wing and rotorcraft flight, movement along entity axes and free rotation using a joystick or a joystick-like widget. Scripting and record/playback features support regression testing, demonstrations and other tasks needing exact reproduction of certain sequences of events. A packet-level snoop feature allows the user to examine the contents of CIGI messages, image generator response times and latencies. A Heartbeat Monitor Window shows a graphical timing history of the Image Generator's data frame rate. Other features include explicit packet creation, animation control, missile flyouts and a situation display window (Host Emulator 3.x only). === Multi-Purpose Viewer === The Multi-Purpose Viewer (MPV) provides the basic functionality expected of an Image Generator, such as loading and displaying a terrain database, displaying entities and so forth. The Multi-Purpose Viewer can be used as a surrogate to manipulate the interface when a real Image Generator is not available. The MPV is capable of operating with both the Windows and Linux operating systems. === CIGI Class Library === The CCL is an object-oriented software interface that automatically handles message composition and decomposition (i.e. packing, unpacking and byte swapping to the ICD specification) on both the Host and Image Generator sides of the interface. The CCL interprets Host or Image Generator messages based on compile time parameters. It also performs error handling and translation between different versions of CIGI. Each packet type has its own class. The individual packet members are accessed through packet class accessors. Outgoing messages are constructed by placing each packet into the outgoing buffer using a streaming operator. Incoming messages are parsed using callback or event-based mechanisms that supply the using program with fully populated packet objects. === Current tool suite === A set of CIGI development tools are managed and maintained by the SISO CIGI Product Support Group. The latest packages are available on SourceForge. Comments/Suggestions to the package can be directed to the SISO discussion board at: https://discussions.sisostds.org/index.htm?A0=SAC-PSG-CIGI Archived 2017-09-13 at the Wayback Machine === Wireshark === Wireshark is a free and open source packet analyzer. It is used for network troubleshooting, analysis, software and communications protocol development, and education. Wireshark provides a dissector for CIGI packets. As of October 2016, “The CIGI dissector is fully functional for CIGI version 2 and 3. Version 1 is not yet implemented.” === Older versions of CIGI === A CIGI Interface Control Document (ICD) and development suite is available in open source format. The tools, ICD, and accompanying user documentation can be found and downloaded from the CIGI sourceforge web site. The SourceForge version of the MPV is limited in its support of CIGI data packets and is intended to grow as needs arise. The MPV uses CIGI 3 as its interface, but the MPV is backward-compatible with earlier CIGI versions through the use of the CCL. The MPV uses the Open Scene Graph library to render a scene. The scene graph is manipulated according to the CIGI commands received from the Host via the CCL. The MPV itself is an application layer that consists of a small kernel leveraging heavily on a plug-in architecture for ease of maintainability and flexibility. An implementer can implement the interface from scratch, however a full suite of integration tools is available. These tools consist of three elements. The Host Emulator (HE), the Multi-Purpose Viewer (MPV), and the CIGI Class Library (CCL).
TU Me
TU (formerly TU Me) is a digital platform developed by Telefónica and operated through its subsidiary Telefónica Innovación Digital. Initially launched in 2012 as a messaging app under the name TU Me, the brand was later revived in 2024 to designate a new suite of digital products focused on privacy, cybersecurity, and digital identity. == TU Me (2012–2014) == TU Me was a free mobile application released by Telefónica in May 2012. It allowed users to make voice calls, send texts, share photos and locations, and store conversation history in the cloud. The app was available for iOS and Android platforms, positioned as an alternative to services like WhatsApp and Viber. Despite early interest, TU Me was discontinued a few years later and removed from major app stores. Telefónica did not continue development of this version beyond its initial release cycle. == TU (2024–present) == In January 2024, Telefónica relaunched the brand TU through its technology subsidiary Telefónica Innovación Digital. Unlike its predecessor, the new TU is not a messaging app but a digital product platform offering solutions in cybersecurity, identity management, and cryptographic technology. The project includes a range of services built with technologies such as artificial intelligence, blockchain, and post-quantum cryptography. It operates independently from Movistar and targets both individual users and businesses. Notable products include: Latch: a digital access control system for securing user accounts. VerifAI: an AI-based tool for detecting manipulated media (images, audio, video). Metashield: software to identify and remove hidden metadata in documents. Wallet: a digital wallet for managing crypto-assets. Quantum Drop: encrypted file transfer system using post-quantum technology. Quantum Encryption: a security tool for IoT and private networks. Gallery: a blockchain-based digital art marketplace.
Nouvelle AI
Nouvelle artificial intelligence (Nouvelle AI) is an approach to artificial intelligence pioneered in the 1980s by Rodney Brooks, who was then part of MIT artificial intelligence laboratory. Nouvelle AI differs from classical AI by aiming to produce robots with intelligence levels similar to insects. Researchers believe that intelligence can emerge organically from simple behaviors as these intelligences interacted with the "real world", instead of using the constructed worlds which symbolic AIs typically needed to have programmed into them. == Motivation == The differences between nouvelle AI and symbolic AI are apparent in early robots Shakey and Freddy. These robots contained an internal model (or "representation") of their micro-worlds consisting of symbolic descriptions. As a result, this structure of symbols had to be renewed as the robot moved or the world changed. Shakey's planning programs assessed the program structure and broke it down into the necessary steps to complete the desired action. This level of computation required a large amount time to process, so Shakey typically performed its tasks very slowly. Symbolic AI researchers had long been plagued by the problem of updating, searching, and otherwise manipulating the symbolic worlds inside their AIs. A nouvelle system refers continuously to its sensors rather than to an internal model of the world. It processes the external world information it needs from the senses when it is required. As Brooks puts it, "the world is its own best model--always exactly up to date and complete in every detail." A central idea of nouvelle AI is that simple behaviors combine to form more complex behaviors over time. For example, simple behaviors can include elements like "move forward" and "avoid obstacles." A robot using nouvelle AI with simple behaviors like collision avoidance and moving toward a moving object could possibly come together to produce a more complex behavior like chasing a moving object. === The frame problem === The frame problem describes an issue with using first-order logic (FOL) to express facts about a robot in the world. Representing the state of a robot with traditional FOL requires the use of many axioms (symbolic language) to imply that things about an environment do not change arbitrarily. Nouvelle AI seeks to sidestep the frame problem by dispensing with filling the AI or robot with volumes of symbolic language and instead letting more complex behaviors emerge by combining simpler behavioral elements. === Embodiment === The goal of traditional AI was to build intelligences without bodies, which would only have been able to interact with the world via keyboard, screen, or printer. However, nouvelle AI attempts to build embodied intelligence situated in the real world. Brooks quotes approvingly from the brief sketches that Turing gave in 1948 and 1950 of the "situated" approach. Turing wrote of equipping a machine "with the best sense organs that money can buy" and teaching it "to understand and speak English" by a process that would "follow the normal teaching of a child." This approach was contrasted to the others where they focused on abstract activities such as playing chess. == Brooks' robots == === Insectoid robots === Brooks focused on building robots that acted like simple insects while simultaneously working to remove some traditional AI characteristics. He created insect-like robots, named Allen and Herbert after cognitive science and AI pioneers Allen Newell and Herbert A. Simon. Brooks's insectoid robots contained no internal models of the world. Herbert, for example, discarded a high volume of the information received from its sensors and never stored information for more than two seconds. ==== Allen ==== Allen had a ring of twelve ultrasonic sonars as its primary sensors and three independent behavior-producing modules. These modules were programmed to avoid both stationary and moving objects. With only this module activated, Allen stayed in the middle of a room until an object approached and then it ran away while avoiding obstacles in its way. ==== Herbert ==== Herbert used infrared sensors to avoid obstacles and a laser system to collect 3D data over a distance of about 12 feet. Herbert also carried a number of simple sensors in its "hand." The robot's testing ground was the real world environment of the busy offices and workspaces of the MIT AI lab where it searched for empty soda cans and carried them away, a seemingly goal-oriented activity that emerged as a result of 15 simple behavior units combining. As a parallel, Simon noted that an ant's complicated path is due to the structure of its environment rather than the depth of its thought processes. ==== Other insectoid robots ==== Other robots by Brooks' team were Genghis and Squirt. Genghis had six legs and was able to walk over rough terrain and follow a human. Squirt's behavior modules had it stay in dark corners until it heard a noise, then it would begin to follow the source of the noise. Brooks agreed that the level of nouvelle AI had come near the complexity of a real insect, which raised a question about whether or not insect level-behavior was and is a reasonable goal for nouvelle AI. === Humanoid robots === Brooks' own recent work has taken the opposite direction to that proposed by Von Neumann in the quotations "theorists who select the human nervous system as their model are unrealistically picking 'the most complicated object under the sun,' and that there is little advantage in selecting instead the ant, since any nervous system at all exhibits exceptional complexity." ==== Cog ==== In the 1990s, Brooks decided to pursue the goal of human-level intelligence and, with Lynn Andrea Stein, built a humanoid robot called Cog. Cog is a robot with an extensive collection of sensors, a face, and arms (among other features) that allow it to interact with the world and gather information and experience so as to assemble intelligence organically in the manner described above by Turing. The team believed that Cog would be able to learn and able to find a correlation between the sensory information it received and its actions, and to learn common sense knowledge on its own. As of 2003, all development of the project had ceased.
Hierarchical RBF
In computer graphics, hierarchical RBF is an interpolation method based on radial basis functions (RBFs). Hierarchical RBF interpolation has applications in treatment of results from a 3D scanner, terrain reconstruction, and the construction of shape models in 3D computer graphics (such as the Stanford bunny, a popular 3D model). This problem is informally named as "large scattered data point set interpolation." == Method == The steps of the interpolation method (in three dimensions) are as follows: Let the scattered points be presented as set P = { c i = ( x i , y i , z i ) | i = 1 N ⊂ R 3 } {\displaystyle \mathbf {P} =\{\mathbf {c} _{i}=(\mathbf {x} _{i},\mathbf {y} _{i},\mathbf {z} _{i})\vert _{i=1}^{N}\subset \mathbb {R} ^{3}\}} Let there exist a set of values of some function in scattered points H = { h i | i = 1 N ⊂ R } {\displaystyle \mathbf {H} =\{\mathbf {h} _{i}\vert _{i=1}^{N}\subset \mathbb {R} \}} Find a function f ( x ) {\displaystyle \mathbf {f} (\mathbf {x} )} that will meet the condition f ( x ) = 1 {\displaystyle \mathbf {f} (\mathbf {x} )=1} for points lying on the shape and f ( x ) ≠ 1 {\displaystyle \mathbf {f} (\mathbf {x} )\neq 1} for points not lying on the shape As J. C. Carr et al. showed, this function takes the form f ( x ) = ∑ i = 1 N λ i φ ( x , c i ) {\displaystyle \mathbf {f} (\mathbf {x} )=\sum _{i=1}^{N}\lambda _{i}\varphi (\mathbf {x} ,\mathbf {c} _{i})} where φ {\displaystyle \varphi } is a radial basis function and λ {\displaystyle \lambda } are the coefficients that are the solution of the following linear system of equations: [ φ ( c 1 , c 1 ) φ ( c 1 , c 2 ) . . . φ ( c 1 , c N ) φ ( c 2 , c 1 ) φ ( c 2 , c 2 ) . . . φ ( c 2 , c N ) . . . . . . . . . . . . φ ( c N , c 1 ) φ ( c N , c 2 ) . . . φ ( c N , c N ) ] ∗ [ λ 1 λ 2 . . . λ N ] = [ h 1 h 2 . . . h N ] {\displaystyle {\begin{bmatrix}\varphi (c_{1},c_{1})&\varphi (c_{1},c_{2})&...&\varphi (c_{1},c_{N})\\\varphi (c_{2},c_{1})&\varphi (c_{2},c_{2})&...&\varphi (c_{2},c_{N})\\...&...&...&...\\\varphi (c_{N},c_{1})&\varphi (c_{N},c_{2})&...&\varphi (c_{N},c_{N})\end{bmatrix}}{\begin{bmatrix}\lambda _{1}\\\lambda _{2}\\...\\\lambda _{N}\end{bmatrix}}={\begin{bmatrix}h_{1}\\h_{2}\\...\\h_{N}\end{bmatrix}}} For determination of surface, it is necessary to estimate the value of function f ( x ) {\displaystyle \mathbf {f} (\mathbf {x} )} in specific points x. A lack of such method is a considerable complication on the order of O ( n 2 ) {\displaystyle \mathbf {O} (\mathbf {n} ^{2})} to calculate RBF, solve system, and determine surface. == Other methods == Reduce interpolation centers ( O ( n 2 ) {\displaystyle \mathbf {O} (\mathbf {n} ^{2})} to calculate RBF and solve system, O ( m n ) {\displaystyle \mathbf {O} (\mathbf {m} \mathbf {n} )} to determine surface) Compactly support RBF ( O ( n log n ) {\displaystyle \mathbf {O} (\mathbf {n} \log {\mathbf {n} })} to calculate RBF, O ( n 1.2..1.5 ) {\displaystyle \mathbf {O} (\mathbf {n} ^{1.2..1.5})} to solve system, O ( m log n ) {\displaystyle \mathbf {O} (\mathbf {m} \log {\mathbf {n} })} to determine surface) FMM ( O ( n 2 ) {\displaystyle \mathbf {O} (\mathbf {n} ^{2})} to calculate RBF, O ( n log n ) {\displaystyle \mathbf {O} (\mathbf {n} \log {\mathbf {n} })} to solve system, O ( m + n log n ) {\displaystyle \mathbf {O} (\mathbf {m} +\mathbf {n} \log {\mathbf {n} })} to determine surface) == Hierarchical algorithm == A hierarchical algorithm allows for an acceleration of calculations due to decomposition of intricate problems on the great number of simple (see picture). In this case, hierarchical division of space contains points on elementary parts, and the system of small dimension solves for each. The calculation of surface in this case is taken to the hierarchical (on the basis of tree-structure) calculation of interpolant. A method for a 2D case is offered by Pouderoux J. et al. For a 3D case, a method is used in the tasks of 3D graphics by W. Qiang et al. and modified by Babkov V.