Dental artificial intelligence (Dental AI) refers to the application of artificial intelligence (AI) and machine-learning methods to oral healthcare data. These systems can be used to find patterns or make predictions that can aid in diagnosis, treatment, patient communication, or practice management. == History and development == Research into AI for dentistry dates to the 1990s and 2000s, alongside early CAD/CAM and image-analysis work in dental radiology. Recent developments in deep learning, especially those involving computer vision, such as convolutional neural networks, trained on large image datasets, led to a rapid improvement in performance, as well as a move from prototype technology to productization suitable for use in dental chairs. Dental schools and continuing education programs started incorporating AI content in the 2020s. == Definition and core technologies == The dental AI software accomplishes this task by using various dental images and patient data. Dental images and data used by the dental AI software include bitewing and periapical X-rays, complete mouth X-rays, detailed 3D images, intraoral images, and the patient’s medical history. The dental AI software utilizes several core technologies in accomplishing its task of assisting the dentist. First, the dental AI software utilizes machine learning and deep learning using programs that can learn from examples. Such programs are referred to as convolutional neural network (CNN) and can detect cavities and identify bone changes related to gum disease. The dental AI software utilizes computer vision, which enables the AI software to identify and quantify important features in images and data, whether they are 2D images or 3D images. Natural language processing (NLP) is used for the AI software to understand written text and can automatically generate dental notes and communicate with the patient. Furthermore, the dental AI software utilizes predictive analytics to identify patients that are more prone to dental complications and can suggest the best intervals for checkups or future dental procedures. == Applications in dentistry == Reported clinical and operational applications include diagnostic assistance for caries and periodontal disease, treatment planning assistance, patient education overlays, quality assurance, curriculum assistance for dental education, and claims documentation. Systematic reviews continue to find image-based applications such as caries detection with some variability in study design and a need for prospective validation. == Academic research and clinical validation == Several peer-reviewed studies have measured the effectiveness of AI for applications such as interproximal caries detection and periodontal bone level assessment, showing improvements over unaided readings with a focus on bias within the dataset. The Dental AI Council found variability among clinicians for diagnosis and treatment planning, suggesting the use of a standard tool as an assist. == Industry adoption == Multiple vendors offer FDA-cleared chairside AI for dental imaging: Pearl — Received U.S. FDA 510(k) clearance for its real-time radiologic aid (“Second Opinion”) in 2022 (2D), with subsequent clearances including pediatric and CBCT (“Second Opinion 3D”). TIME gave “Second Opinion” a special mention on its Best Inventions of 2022 list. Overjet — FDA-cleared for bone-level quantification and detection/outline of caries and calculus (e.g., K210187), with additional clearances expanding capabilities. VideaHealth — Received an FDA 510(k) covering 30+ detections across common dental findings (K232384), including indications for patients ages 3 and up; trade coverage has described elements of this as the first pediatric dental-AI clearance. == Regulations == In the U.S., AI-enabled dental imaging software is generally reviewed via the FDA’s 510(k) pathway. The FDA maintains a public AI-Enabled Medical Devices List, which includes numerous medical-imaging AI tools (including dental). Specific dental clearances include Overjet (K210187), VideaHealth (K232384), and Pearl entries such as “Second Opinion 3D” (K243989).
Conditional random field
Conditional random fields (CRFs) are a class of statistical modeling methods often applied in pattern recognition and machine learning and used for structured prediction. Whereas a classifier predicts a label for a single sample without considering "neighbouring" samples, a CRF can take context into account. To do so, the predictions are modelled as a graphical model, which represents the presence of dependencies between the predictions. The kind of graph used depends on the application. For example, in natural language processing, "linear chain" CRFs are popular, for which each prediction is dependent only on its immediate neighbours. In image processing, the graph typically connects locations to nearby and/or similar locations to enforce that they receive similar predictions. Other examples where CRFs are used are: labeling or parsing of sequential data for natural language processing or biological sequences, part-of-speech tagging, shallow parsing, named entity recognition, gene finding, peptide critical functional region finding, and object recognition and image segmentation in computer vision. == Description == CRFs are a type of discriminative undirected probabilistic graphical model. Lafferty, McCallum and Pereira define a CRF on observations X {\displaystyle {\boldsymbol {X}}} and random variables Y {\displaystyle {\boldsymbol {Y}}} as follows: Let G = ( V , E ) {\displaystyle G=(V,E)} be a graph such that Y = ( Y v ) v ∈ V {\displaystyle {\boldsymbol {Y}}=({\boldsymbol {Y}}_{v})_{v\in V}} , so that Y {\displaystyle {\boldsymbol {Y}}} is indexed by the vertices of G {\displaystyle G} . Then ( X , Y ) {\displaystyle ({\boldsymbol {X}},{\boldsymbol {Y}})} is a conditional random field when each random variable Y v {\displaystyle {\boldsymbol {Y}}_{v}} , conditioned on X {\displaystyle {\boldsymbol {X}}} , obeys the Markov property with respect to the graph; that is, its probability is dependent only on its neighbours in G and not its past states: P ( Y v | X , { Y w : w ≠ v } ) = P ( Y v | X , { Y w : w ∼ v } ) {\displaystyle P({\boldsymbol {Y}}_{v}|{\boldsymbol {X}},\{{\boldsymbol {Y}}_{w}:w\neq v\})=P({\boldsymbol {Y}}_{v}|{\boldsymbol {X}},\{{\boldsymbol {Y}}_{w}:w\sim v\})} , where w ∼ v {\displaystyle {\mathit {w}}\sim v} means that w {\displaystyle w} and v {\displaystyle v} are neighbors in G {\displaystyle G} . What this means is that a CRF is an undirected graphical model whose nodes can be divided into exactly two disjoint sets X {\displaystyle {\boldsymbol {X}}} and Y {\displaystyle {\boldsymbol {Y}}} , the observed and output variables, respectively; the conditional distribution p ( Y | X ) {\displaystyle p({\boldsymbol {Y}}|{\boldsymbol {X}})} is then modeled. === Inference === For general graphs, the problem of exact inference in CRFs is intractable. The inference problem for a CRF is basically the same as for an MRF and the same arguments hold. However, there exist special cases for which exact inference is feasible: If the graph is a chain or a tree, message passing algorithms yield exact solutions. The algorithms used in these cases are analogous to the forward-backward and Viterbi algorithm for the case of HMMs. If the CRF only contains pair-wise potentials and the energy is submodular, combinatorial min cut/max flow algorithms yield exact solutions. If exact inference is impossible, several algorithms can be used to obtain approximate solutions. These include: Loopy belief propagation Alpha expansion Mean field inference Linear programming relaxations === Parameter learning === Learning the parameters θ {\displaystyle \theta } is usually done by maximum likelihood learning for p ( Y i | X i ; θ ) {\displaystyle p(Y_{i}|X_{i};\theta )} . If all nodes have exponential family distributions and all nodes are observed during training, this optimization is convex. It can be solved for example using gradient descent algorithms, or Quasi-Newton methods such as the L-BFGS algorithm. On the other hand, if some variables are unobserved, the inference problem has to be solved for these variables. Exact inference is intractable in general graphs, so approximations have to be used. === Examples === In sequence modeling, the graph of interest is usually a chain graph. An input sequence of observed variables X {\displaystyle X} represents a sequence of observations and Y {\displaystyle Y} represents a hidden (or unknown) state variable that needs to be inferred given the observations. The Y i {\displaystyle Y_{i}} are structured to form a chain, with an edge between each Y i − 1 {\displaystyle Y_{i-1}} and Y i {\displaystyle Y_{i}} . As well as having a simple interpretation of the Y i {\displaystyle Y_{i}} as "labels" for each element in the input sequence, this layout admits efficient algorithms for: model training, learning the conditional distributions between the Y i {\displaystyle Y_{i}} and feature functions from some corpus of training data. decoding, determining the probability of a given label sequence Y {\displaystyle Y} given X {\displaystyle X} . inference, determining the most likely label sequence Y {\displaystyle Y} given X {\displaystyle X} . The conditional dependency of each Y i {\displaystyle Y_{i}} on X {\displaystyle X} is defined through a fixed set of feature functions of the form f ( i , Y i − 1 , Y i , X ) {\displaystyle f(i,Y_{i-1},Y_{i},X)} , which can be thought of as measurements on the input sequence that partially determine the likelihood of each possible value for Y i {\displaystyle Y_{i}} . The model assigns each feature a numerical weight and combines them to determine the probability of a certain value for Y i {\displaystyle Y_{i}} . Linear-chain CRFs have many of the same applications as conceptually simpler hidden Markov models (HMMs), but relax certain assumptions about the input and output sequence distributions. An HMM can loosely be understood as a CRF with very specific feature functions that use constant probabilities to model state transitions and emissions. Conversely, a CRF can loosely be understood as a generalization of an HMM that makes the constant transition probabilities into arbitrary functions that vary across the positions in the sequence of hidden states, depending on the input sequence. Notably, in contrast to HMMs, CRFs can contain any number of feature functions, the feature functions can inspect the entire input sequence X {\displaystyle X} at any point during inference, and the range of the feature functions need not have a probabilistic interpretation. == Variants == === Higher-order CRFs and semi-Markov CRFs === CRFs can be extended into higher order models by making each Y i {\displaystyle Y_{i}} dependent on a fixed number k {\displaystyle k} of previous variables Y i − k , . . . , Y i − 1 {\displaystyle Y_{i-k},...,Y_{i-1}} . In conventional formulations of higher order CRFs, training and inference are only practical for small values of k {\displaystyle k} (such as k ≤ 5), since their computational cost increases exponentially with k {\displaystyle k} . However, another recent advance has managed to ameliorate these issues by leveraging concepts and tools from the field of Bayesian nonparametrics. Specifically, the CRF-infinity approach constitutes a CRF-type model that is capable of learning infinitely-long temporal dynamics in a scalable fashion. This is effected by introducing a novel potential function for CRFs that is based on the Sequence Memoizer (SM), a nonparametric Bayesian model for learning infinitely-long dynamics in sequential observations. To render such a model computationally tractable, CRF-infinity employs a mean-field approximation of the postulated novel potential functions (which are driven by an SM). This allows for devising efficient approximate training and inference algorithms for the model, without undermining its capability to capture and model temporal dependencies of arbitrary length. There exists another generalization of CRFs, the semi-Markov conditional random field (semi-CRF), which models variable-length segmentations of the label sequence Y {\displaystyle Y} . This provides much of the power of higher-order CRFs to model long-range dependencies of the Y i {\displaystyle Y_{i}} , at a reasonable computational cost. Finally, large-margin models for structured prediction, such as the structured Support Vector Machine can be seen as an alternative training procedure to CRFs. === Latent-dynamic conditional random field === Latent-dynamic conditional random fields (LDCRF) or discriminative probabilistic latent variable models (DPLVM) are a type of CRFs for sequence tagging tasks. They are latent variable models that are trained discriminatively. In an LDCRF, like in any sequence tagging task, given a sequence of observations x = x 1 , … , x n {\displaystyle x_{1},\dots ,x_{n}} , the main problem the model must solve is how to assign a sequence of labels y = y 1 , … , y n {\displaystyle y_{1},\dots ,y_{n}} from one finite set
Pixel aspect ratio
A pixel aspect ratio (PAR) is a mathematical ratio that describes how the width of a pixel in a digital image compares to the height of that pixel. Most digital imaging systems display an image as a grid of tiny, square pixels. However, some imaging systems, especially those that must be compatible with standard-definition television motion pictures, display an image as a grid of rectangular pixels, in which the pixel width and height are different. Pixel aspect ratio describes this difference. Use of pixel aspect ratio mostly involves pictures pertaining to standard-definition television and some other exceptional cases. Most other imaging systems, including those that comply with SMPTE standards and practices, use square pixels. PAR is also known as sample aspect ratio and abbreviated SAR, though it can be confused with storage aspect ratio. == Introduction == The ratio of the width to the height of an image is known as the aspect ratio, or more precisely the display aspect ratio (DAR) – the aspect ratio of the image as displayed; for TV, DAR was traditionally 4:3 (a.k.a. fullscreen), with 16:9 (a.k.a. widescreen) now the standard for HDTV. In digital images, there is a distinction with the storage aspect ratio (SAR), which is the ratio of pixel dimensions. If an image is displayed with square pixels, then these ratios agree; if not, then non-square, "rectangular" pixels are used, and these ratios disagree. The aspect ratio of the pixels themselves is known as the pixel aspect ratio (PAR) – for square pixels this is 1:1 – and these are related by the identity: Rearranging (solving for PAR) yields: For example: A 640 × 480 VGA image has a SAR of 640/480 = 4:3, and if displayed on a 4:3 display (DAR = 4:3) has square pixels, hence a PAR of 1:1. By contrast, a 720 × 576 D-1 PAL image has a SAR of 720/576 = 5:4, but if displayed on a 4:3 display (DAR = 4:3) the PAR is 4/3 : 5/4 = 16:15 ≈ 1.066. This means that the pixels of the PAL picture must be "stretched" by this amount to fit in the 4:3 display. In analog images such as film there is no notion of pixel, nor notion of SAR or PAR, but in the digitization of analog images the resulting digital image has pixels, hence SAR (and accordingly PAR, if displayed at the same aspect ratio as the original). Non-square pixels arise often in early digital TV standards, related to digitalization of analog TV signals – whose vertical and "effective" horizontal resolutions differ and are thus best described by non-square pixels – and also in some digital video cameras and computer display modes, such as Color Graphics Adapter (CGA). Today they arise also in transcoding between resolutions with different SARs. Actual displays do not generally have non-square pixels, though digital sensors might; they are rather a mathematical abstraction used in resampling images to convert between resolutions. There are several complicating factors in understanding PAR, particularly as it pertains to digitization of analog video: First, analog video does not have pixels, but rather a raster scan, and thus has a well-defined vertical resolution (the lines of the raster), but not a well-defined horizontal resolution, since each line is an analog signal. However, by a standardized sampling rate, the effective horizontal resolution can be determined by the sampling theorem, as is done below. Second, due to overscan, some of the lines at the top and bottom of the raster are not visible, as are some of the possible image on the left and right – see Overscan: Analog to digital resolution issues. Also, the resolution may be rounded (DV NTSC uses 480 lines, rather than the 486 that are possible). Third, analog video signals are interlaced – each image (frame) is sent as two "fields", each with half the lines. Thus either the pixels are twice as tall as they would be without interlacing, or the image is deinterlaced. == Background == Video is presented as a sequential series of images called video frames. Historically, video frames were created and recorded in analog form. As digital display technology, digital broadcast technology, and digital video compression evolved separately, it resulted in video frame differences that must be addressed using pixel aspect ratio. Digital video frames are generally defined as a grid of pixels used to present each sequential image. The horizontal component is defined by pixels (or samples), and is known as a video line. The vertical component is defined by the number of lines, as in 480 lines. Standard-definition television standards and practices were developed as broadcast technologies and intended for terrestrial broadcasting, and were therefore not designed for digital video presentation. Such standards define an image as an array of well-defined horizontal "Lines", well-defined vertical "Line Duration" and a well-defined picture center. However, there is not a standard-definition television standard that properly defines image edges or explicitly demands a certain number of picture elements per line. Furthermore, analog video systems such as NTSC 480i and PAL 576i, instead of employing progressively displayed frames, employ fields or interlaced half-frames displayed in an interwoven manner to reduce flicker and double the image rate for smoother motion. === Analog-to-digital conversion === As a result of computers becoming powerful enough to serve as video editing tools, video digital-to-analog converters and analog-to-digital converters were made to overcome this incompatibility. To convert analog video lines into a series of square pixels, the industry adopted a default sampling rate at which luma values were extracted into pixels. The luma sampling rate for 480i pictures was 12+3⁄11 MHz and for 576i pictures was 14+3⁄4 MHz. The term pixel aspect ratio was first coined when ITU-R BT.601 (commonly known as Rec. 601) specified that standard-definition television pictures are made of lines of exactly 720 non-square pixels. ITU-R BT.601 did not define the exact pixel aspect ratio but did provide enough information to calculate the exact pixel aspect ratio based on industry practices: The standard luma sampling rate of precisely 13+1⁄2 MHz. Based on this information: The pixel aspect ratio for 480i would be 10:11 as: 12 3 11 ÷ 13 1 2 = 10 11 {\displaystyle 12{\tfrac {3}{11}}\div 13{\tfrac {1}{2}}={\tfrac {10}{11}}} The pixel aspect ratio for 576i would be 59:54 as: 14 3 4 ÷ 13 1 2 = 59 54 {\displaystyle 14{\tfrac {3}{4}}\div 13{\tfrac {1}{2}}={\tfrac {59}{54}}} SMPTE RP 187 further attempted to standardize the pixel aspect ratio values for 480i and 576i. It designated 177:160 for 480i or 1035:1132 for 576i. However, due to significant difference with practices in effect by industry and the computational load that they imposed upon the involved hardware, SMPTE RP 187 was simply ignored. SMPTE RP 187 information annex A.4 further suggested the use of 10:11 for 480i. As of this writing, ITU-R BT.601-6, which is the latest edition of ITU-R BT.601, still implies that the pixel aspect ratios mentioned above are correct. === Digital video processing === As stated above, ITU-R BT.601 specified that standard-definition television pictures are made of lines of 720 non-square pixels, sampled with a precisely specified sampling rate. A simple mathematical calculation reveals that a 704 pixel width would be enough to contain a 480i or 576i standard 4:3 picture: A 4:3 480-line picture, digitized with the Rec. 601-recommended sampling rate, would be 704 non-square pixels wide. x 480 × 10 11 = 4 3 ⇒ x = 480 × 11 × 4 10 × 3 = 704 {\displaystyle {\frac {x}{480}}\times {\frac {10}{11}}={\frac {4}{3}}\Rightarrow x={\frac {480\times 11\times 4}{10\times 3}}=704} A 4:3 576-line picture, digitized with the Rec. 601-recommended sampling rate, would be 702+54⁄59 non-square pixels wide. x 576 × 59 54 = 4 3 ⇒ x = 576 × 54 × 4 59 × 3 = 702 54 59 {\displaystyle {\frac {x}{576}}\times {\frac {59}{54}}={\frac {4}{3}}\Rightarrow x={\frac {576\times 54\times 4}{59\times 3}}=702{\tfrac {54}{59}}} Unfortunately, not all standard TV pictures are exactly 4:3: As mentioned earlier, in analog video, the center of a picture is well-defined but the edges of the picture are not standardized. As a result, some analog devices (mostly PAL devices but also some NTSC devices) generated motion pictures that were horizontally (slightly) wider. This also proportionately applies to anamorphic widescreen (16:9) pictures. Therefore, to maintain a safe margin of error, ITU-R BT.601 required sampling 16 more non-square pixels per line (8 more at each edge) to ensure saving all video data near the margins. This requirement, however, had implications for PAL motion pictures. PAL pixel aspect ratios for standard (4:3) and anamorphic wide screen (16:9), respectively 59:54 and 118:81, were awkward for digital image processing, especially for mixing PAL and NTSC video clips. Therefore, video editing products chose the almost equivalent value
Resel
In image analysis, a resel (from resolution element) represents the actual spatial resolution in an image or a volumetric dataset. The number of resels in the image may be lower or equal to the number of pixel/voxels in the image. In an actual image the resels can vary across the image and indeed the local resolution can be expressed as "resels per pixel" (or "resels per voxel"). In functional neuroimaging analysis, an estimate of the number of resels together with random field theory is used in statistical inference. Keith Worsley has proposed an estimate for the number of resels/roughness. The word "resel" is related to the words "pixel", "texel", and "voxel". Waldo R. Tobler is probably among the first to use the word.
Projection-slice theorem
In mathematics, the projection-slice theorem, central slice theorem or Fourier slice theorem in two dimensions states that the results of the following two calculations are equal: Take a two-dimensional function f(r), project (e.g. using the Radon transform) it onto a (one-dimensional) line, and do a Fourier transform of that projection. Take that same function, but do a two-dimensional Fourier transform first, and then slice the function through its origin, parallel to the projection line. In operator terms, if F1 and F2 are the 1- and 2-dimensional Fourier transform operators mentioned above, P1 is the projection operator (which projects a 2-D function onto a 1-D line), S1 is a slice operator (which extracts a 1-D central slice from a function), then F 1 P 1 = S 1 F 2 . {\displaystyle F_{1}P_{1}=S_{1}F_{2}.} This idea can be extended to higher dimensions. This theorem is used, for example, in the analysis of medical CT scans where a "projection" is an x-ray image of an internal organ. The Fourier transforms of these images are seen to be slices through the Fourier transform of the 3-dimensional density of the internal organ, and these slices can be interpolated to build up a complete Fourier transform of that density. The inverse Fourier transform is then used to recover the 3-dimensional density of the object. This technique was first derived by Ronald N. Bracewell in 1956 for a radio-astronomy problem. == The projection-slice theorem in N dimensions == In N dimensions, the projection-slice theorem states that the Fourier transform of the projection of an N-dimensional function f(r) onto an m-dimensional linear submanifold is equal to an m-dimensional slice of the N-dimensional Fourier transform of that function consisting of an m-dimensional linear submanifold through the origin in the Fourier space which is parallel to the projection submanifold. In operator terms: F m P m = S m F N . {\displaystyle F_{m}P_{m}=S_{m}F_{N}.\,} == The generalized Fourier-slice theorem == In addition to generalizing to N dimensions, the projection-slice theorem can be further generalized with an arbitrary change of basis. For convenience of notation, we consider the change of basis to be represented as B, an N-by-N invertible matrix operating on N-dimensional column vectors. Then the generalized Fourier-slice theorem can be stated as F m P m B = S m B − T | B − T | F N {\displaystyle F_{m}P_{m}B=S_{m}{\frac {B^{-T}}{|B^{-T}|}}F_{N}} where B − T = ( B − 1 ) T {\displaystyle B^{-T}=(B^{-1})^{T}} is the transpose of the inverse of the change of basis transform. == Proof in two dimensions == The projection-slice theorem is easily proven for the case of two dimensions. Without loss of generality, we can take the projection line to be the x-axis. There is no loss of generality because if we use a shifted and rotated line, the law still applies. Using a shifted line (in y) gives the same projection and therefore the same 1D Fourier transform results. The rotated function is the Fourier pair of the rotated Fourier transform, for which the theorem again holds. If f(x, y) is a two-dimensional function, then the projection of f(x, y) onto the x axis is p(x) where p ( x ) = ∫ − ∞ ∞ f ( x , y ) d y . {\displaystyle p(x)=\int _{-\infty }^{\infty }f(x,y)\,dy.} The Fourier transform of f ( x , y ) {\displaystyle f(x,y)} is F ( k x , k y ) = ∫ − ∞ ∞ ∫ − ∞ ∞ f ( x , y ) e − 2 π i ( x k x + y k y ) d x d y . {\displaystyle F(k_{x},k_{y})=\int _{-\infty }^{\infty }\int _{-\infty }^{\infty }f(x,y)\,e^{-2\pi i(xk_{x}+yk_{y})}\,dxdy.} The slice is then s ( k x ) {\displaystyle s(k_{x})} s ( k x ) = F ( k x , 0 ) = ∫ − ∞ ∞ ∫ − ∞ ∞ f ( x , y ) e − 2 π i x k x d x d y {\displaystyle s(k_{x})=F(k_{x},0)=\int _{-\infty }^{\infty }\int _{-\infty }^{\infty }f(x,y)\,e^{-2\pi ixk_{x}}\,dxdy} = ∫ − ∞ ∞ [ ∫ − ∞ ∞ f ( x , y ) d y ] e − 2 π i x k x d x {\displaystyle =\int _{-\infty }^{\infty }\left[\int _{-\infty }^{\infty }f(x,y)\,dy\right]\,e^{-2\pi ixk_{x}}dx} = ∫ − ∞ ∞ p ( x ) e − 2 π i x k x d x {\displaystyle =\int _{-\infty }^{\infty }p(x)\,e^{-2\pi ixk_{x}}dx} which is just the Fourier transform of p(x). The proof for higher dimensions is easily generalized from the above example. == The FHA cycle == If the two-dimensional function f(r) is circularly symmetric, it may be represented as f(r), where r = |r|. In this case the projection onto any projection line will be the Abel transform of f(r). The two-dimensional Fourier transform of f(r) will be a circularly symmetric function given by the zeroth-order Hankel transform of f(r), which will therefore also represent any slice through the origin. The projection-slice theorem then states that the Fourier transform of the projection equals the slice or F 1 A 1 = H , {\displaystyle F_{1}A_{1}=H,} where A1 represents the Abel-transform operator, projecting a two-dimensional circularly symmetric function onto a one-dimensional line, F1 represents the 1-D Fourier-transform operator, and H represents the zeroth-order Hankel-transform operator. == Extension to fan beam or cone-beam CT == The projection-slice theorem is suitable for CT image reconstruction with parallel beam projections. It does not directly apply to fanbeam or conebeam CT. The theorem was extended to fan-beam and conebeam CT image reconstruction by Shuang-ren Zhao in 1995.
Inbox by Gmail
Inbox by Gmail was an email service developed by Google. Announced on a limited invitation-only basis on October 22, 2014, it was officially released to the public on May 28, 2015. Inbox was shut down by Google on April 2, 2019. Available on the web, and through mobile apps for Android and iOS, Inbox by Gmail aimed to improve email productivity and organization through several key features. Bundles gathered emails on the same topic together; highlighted surface key details from messages, reminders and assists; and a "snooze" functionality enabled users to control when specific information would appear. Updates to the service enabled an "undo send" feature; a "Smart Reply" feature that automatically generated short reply examples for certain emails; integration with Google Calendar for event organization, previews of newsletters; and a "Save to Inbox" feature that let users save links for later use. Inbox by Gmail received generally positive reviews. At its launch, it was called "minimalist and lovely, full of layers and easy to navigate", with features deemed helpful in finding the right messages—one reviewer noted that the service felt "a lot like the future of email". However, it also received criticism, particularly for a low density of information, algorithms that needed tweaking, and because the service required users to "give up the control" of organizing their own email, meaning that "Anyone who already has a system for organizing their emails will likely find themselves fighting Google's system". Google noted in March 2016 that 10% of all replies on mobile originated from Inbox's Smart Reply feature. Google announced it would discontinue Inbox by Gmail in March 2019, with many of its features integrated into Gmail proper. == Features == Inbox by Gmail scanned the user's incoming Gmail messages for information. It gathered email messages related to the same overall topic into an organized bundle, with a title describing the bundle's content. For example, flight tickets, car rentals, and hotel reservations were grouped under "Travel", giving the user an easier overview of emails. Users could also group emails together manually, to "teach" the Inbox how the user worked. The service highlighted key details and important information in messages, such as flight itineraries, event information, photos and documents. Inbox could retrieve updated information from the Internet, including the real-time status of flights and package deliveries. Users could set reminders to bring up important messages later. When a user needed particular information, Inbox could assist the user by displaying the necessary details. Where Inbox highlights information was not needed immediately, users could "snooze" a message or reminder, with options to make the information reappear at a later time or specific location. In June 2015, Google added an "Undo Send" feature to Inbox, giving the user 10 seconds to undo sending a message. In November 2015, Google added "Smart Reply" functionality to the mobile apps. With Smart Reply, Inbox determined which emails could be answered with a short reply, generating three example responses from which the user could select one with a single tap. Smart Reply (initially available only on the Android and iOS mobile apps) was added to the Inbox website in March 2016, Google announcing that "10% of all your replies on mobile already use Smart Reply". By May 2017, Google said Smart Reply was driving about 12% of replies in inbox on mobile. In April 2016, Google updated Inbox with three new features; Google Calendar event organization, newsletter previews, and a "Save to Inbox" functionality that let the user save links for later use, rather than having to email links to themselves. In December 2017, Google introduced an "Unsubscribe" card that let users easily unsubscribe from mailing lists. The card appeared for email messages (from specific senders) that the user had not opened for a month. A few popular Inbox by Gmail features were subsequently added to Gmail: "Snoozing" of emails Nudges: Gmail could move old messages back to the top of the inbox when it thought a follow up or reply might be required. Hover actions: Placing the mouse cursor over a certain part of the message could quickly effect an action, such as archiving, without its being opened. Smart reply: This feature employed boilerplate text to suggest appropriate replies. Google reportedly wished, at a time then to be decided, to add the "bundles" feature to Gmail, which at the time was available only in Inbox for Gmail. By March 2020, many Inbox features were still missing from Gmail. == Platforms == Inbox by Gmail was announced on a limited invitation-only basis on October 22, 2014, available on the web, and through the Android and iOS mobile operating systems. It was officially released to the public on May 28, 2015. == Reception == David Pierce of The Verge praised the service, writing that it was "minimalist and lovely, full of layers and easy to navigate. It's remarkably fast and smooth on all platforms, and far better on iOS than the Gmail app". However, he criticized the app's low density of information, with only a few emails visible on the screen at a time, making it "a bit of a challenge" for users who need to go through "hundreds of emails" every day. Although positive that "Inbox feels a lot like the future of email", Pierce wrote that there was "plenty of algorithm tweaking and design condensing to do", with particular attention needed on a "compact view" for denser view of information on the screen. Sarah Mitroff of CNET also praised Inbox, writing, "Not only is it visually appealing, it's also full of features that help you find every message you need, when you need it". She added that users must "give up the control" to organize their email, and that it "won't vibe with everyone", but admitted that "if you're willing ... the app will reward you with a smarter and cleaner inbox." Mitroff noted that, initially, users had to coach the app about which bundle was appropriate for certain emails, writing, "It's a tedious process at first, by [sic] in just a few days Inbox starts to get it right." Regarding any downsides of the service, Mitroff wrote that "Inbox has a built-in strategy for managing your emails that works best on its own. Anyone who already has a system for organizing their emails will likely find themselves fighting Google's system". == Discontinuation and legacy == Google ended the service in March 2019. Google called Inbox "a great place to experiment with new ideas" and noted that many of those ideas had been migrated to Gmail. The company wanted, going forward, to focus its resources on a single email system. Several services, like Shortwave, attempted to resurrect some of the features of Inbox by Gmail to attract its old users. Similarly, Inbox Reborn, an actively maintained browser extension developed by a team of volunteer developers from around the world since 2018, aims to recreate the core features and visual style of Inbox by Gmail within the standard Gmail interface. The project continues to focus on preserving functionalities such as email bundling and streamlined workflows to provide users with a familiar productivity experience. Afterwards, most people moved to Spark, Spike, or Newton. According to a product manager at Google, a "more focused approach" regarding email was the companies goal. This is likely the reason they moved away from Inbox.
Haskins Laboratories
Haskins Laboratories, Inc. is an independent research laboratory, founded in 1935 and located in New Haven, Connecticut since 1970. Many current Haskins researchers are affiliated with Yale University's Child Study Center and/or the University of Connecticut. Haskins is a multidisciplinary and international community of researchers who conduct basic research on spoken and written language and global literacy. A guiding perspective of their research has been to view speech and language as emerging from biological processes, including those of adaptation, response to stimuli, and conspecific interaction. Haskins Laboratories has a long history of technological and theoretical innovation, from creating systems of rules for speech synthesis and development of an early working prototype of a reading machine for the blind to developing the landmark concept of phonemic awareness as the critical preparation for learning to read an alphabetic writing system. == Research tools and facilities == Haskins Laboratories is equipped, in-house, with a comprehensive suite of tools and capabilities to advance its mission of research into language and literacy. As of 2014, these included: Anechoic chamber Electroencephalography BioSemi 264 electrode, 24 bit Active Two System EGI 128 electrode, Geodesic EEG System 300 Electromagnetic articulography (EMMA) Carstens AG501 NDI WAVE Eye tracking: HL is equipped with 3 SR Research eye-trackers. 2 Model Eyelink 1000 systems. 1 Model Eyelink 1000plus system. Magnetic resonance imaging: Haskins has access to MRI scanners through agreements with the University of Connecticut and the Yale School of Medicine. On-site, HL has a Linux computer cluster dedicated to analysis of MRI data. Motion capture: HL is equipped with a Vicon motion capture system with one Basler high-speed digital camera, six Vicon MX T-20 cameras and a Vicon MX Giganet for synching camera data and connecting cameras to the data capture computer. Near infrared spectroscopy: HL has a TechEn CW6 8x8 system (four emitters; eight detectors). Ultrasound sonogram == History == Many researchers have contributed to scientific breakthroughs at Haskins Laboratories since its founding. All of them are indebted to the pioneering work and leadership of Caryl Parker Haskins, Franklin S. Cooper, Alvin Liberman, Seymour Hutner and Luigi Provasoli. The history presented here focuses on the research program of the division of Haskins Laboratories that, since the 1940s, has been most well known for its work in the areas of speech, language, and reading. === 1930s === Caryl Haskins and Franklin S. Cooper established Haskins Laboratories in 1935. It was originally affiliated with Harvard University, MIT, and Union College in Schenectady, NY. Caryl Haskins conducted research in microbiology, radiation physics, and other fields in Cambridge, MA and Schenectady. In 1939 Haskins Laboratories moved its center to New York City. Seymour Hutner joined the staff to set up a research program in microbiology, genetics, and nutrition. The descendant of the division led by Hutner program eventually became a department of Pace University in New York. The two identically named organizations are no longer formally affiliated. === 1940s === The U. S. Office of Scientific Research and Development, under Vannevar Bush asked Haskins Laboratories to evaluate and develop technologies for assisting blinded World War II veterans. Experimental psychologist Alvin Liberman joined Haskins Laboratories to assist in developing a "sound alphabet" to represent the letters in a text for use in a reading machine for the blind. Luigi Provasoli joined Haskins Laboratories to set up a research program in marine biology. The program in marine biology moved to Yale University in 1970 and disbanded with Provasoli's retirement in 1978. === 1950s === Franklin S. Cooper invented the pattern playback, a machine that converts pictures of the acoustic patterns of speech back into sound. With this device, Alvin Liberman, Cooper, and Pierre Delattre (and later joined by Katherine Safford Harris, Leigh Lisker, Arthur Abramson, and others), discovered the acoustic cues for the perception of phonetic segments (consonants and vowels). Liberman and colleagues proposed a motor theory of speech perception to resolve the acoustic complexity: they hypothesized that we perceive speech by tapping into a biological specialization, a speech module, that contains knowledge of the acoustic consequences of articulation. Liberman, aided by Frances Ingemann and others, organized the results of the work on speech cues into a groundbreaking set of rules for speech synthesis by the Pattern Playback. === 1960s === Franklin S. Cooper and Katherine Safford Harris, working with Peter MacNeilage, were the first researchers in the U.S. to use electromyographic techniques, pioneered at the University of Tokyo, to study the neuromuscular organization of speech. Leigh Lisker and Arthur Abramson looked for simplification at the level of articulatory action in the voicing of certain contrasting consonants. They showed that many acoustic properties of voicing contrasts arise from variations in voice onset time, the relative phasing of the onset of vocal cord vibration and the end of a consonant. Their work has been widely replicated and elaborated, here and abroad, over the following decades. Donald Shankweiler and Michael Studdert-Kennedy used a dichotic listening technique (presenting different nonsense syllables simultaneously to opposite ears) to demonstrate the dissociation of phonetic (speech) and auditory (nonspeech) perception by finding that phonetic structure devoid of meaning is an integral part of language, typically processed in the left cerebral hemisphere. Liberman, Cooper, Shankweiler, and Studdert-Kennedy summarized and interpreted fifteen years of research in "Perception of the Speech Code", still among the most cited papers in the speech literature. It set the agenda for many years of research at Haskins and elsewhere by describing speech as a code in which speakers overlap (or coarticulate) segments to form syllables. Researchers at Haskins connected their first computer to a speech synthesizer designed by Haskins Laboratories' engineers. Ignatius Mattingly, with British collaborators, John N. Holmes and J.N. Shearme, adapted the Pattern playback rules to write the first computer program for synthesizing continuous speech from a phonetically spelled input. A further step toward a reading machine for the blind combined Mattingly's program with an automatic look-up procedure for converting alphabetic text into strings of phonetic symbols. === 1970s === In 1970, Haskins Laboratories moved to New Haven, Connecticut, and entered into affiliation agreements with Yale University and the University of Connecticut; Haskins remains fully independent of both Yale and UConn, administratively and financially. The lab's original location in New Haven, at 270 Crown Street (from 1970 to 2005), was leased from Yale University. Isabelle Liberman, Donald Shankweiler, and Alvin Liberman teamed up with Ignatius Mattingly to study the relationship between speech perception and reading, a topic implicit in Haskins Laboratories' research program since its inception. They developed the concept of phonemic awareness, the knowledge that would-be readers must be aware of the phonemic structure of their language in order to be able to read. Leonard Katz related the work to contemporary cognitive theory and provided expertise in experimental design and data analysis. Under the broad rubric of the "alphabetic principle", this is the core of the lab's present program of reading pedagogy. Patrick Nye joined Haskins Laboratories to lead a team working on the reading machine for the blind. The project culminated when the addition of an optical character recognizer allowed investigators to assemble the first automatic text-to-speech reading machine. By the end of the decade this technology had advanced to the point where commercial concerns assumed the task of designing and manufacturing reading machines for the blind. In 1973, Franklin S. Cooper was selected to form a panel of six experts charged with investigating the famous 18-minute gap in the White House office tapes of President Richard Nixon related to the Watergate scandal. Building on earlier work, Philip Rubin developed the sinewave synthesis program, which was then used by Robert Remez, Rubin, and colleagues to show that listeners can perceive continuous speech without traditional speech cues from a pattern of sinewaves that track the changing resonances of the vocal tract. This paved the way for a view of speech as a dynamic pattern of trajectories through articulatory-acoustic space. Philip Rubin and colleagues developed Paul Mermelstein's anatomically simplified vocal tract model, originally worked on at Bell Laboratories, into the first articulatory synthesizer that can be controlled in a phy