Minimum information standard

Minimum information standard

Minimum information standards are sets of guidelines and formats for reporting data derived by specific high-throughput methods. Their purpose is to ensure the data generated by these methods can be easily verified, analysed and interpreted by the wider scientific community. Ultimately, they facilitate the transfer of data from journal articles (unstructured data) into databases (structured data) in a form that enables data to be mined across multiple data sets. Minimal information standards are available for a vast variety of experiment types including microarray (MIAME), RNAseq (MINSEQE), metabolomics (MSI) and proteomics (MIAPE). Minimum information standards typically have two parts. Firstly, there is a set of reporting requirements – typically presented as a table or a checklist. Secondly, there is a data format. Information about an experiment needs to be converted into the appropriate data format for it to be submitted to the relevant database. In the case of MIAME, the data format is provided in spreadsheet format (MAGE-TAB). Some of the communities that maintain minimum information standards also provide tools to help experimental researchers to annotate their data. == MI Standards == The individual minimum information standards are brought by the communities of cross-disciplinary specialists focused on the problematic of the specific method used in experimental biology. The standards then provide specifications what information about the experiments (metadata) is crucial and important to be reported together with the resultant data to make it comprehensive. The need for this standardization is largely driven by the development of high-throughput experimental methods that provide tremendous amounts of data. The development of minimum information standards of different methods is since 2008 being harmonized by "Minimum Information about a Biomedical or Biological Investigation" (MIBBI) project. === MIAPPE, Minimum Information About a Plant Phenotyping Experiment === MIAPPE is an open, community driven project to harmonize data from plant phenotyping experiments. MIAPPE comprises both a conceptual checklist of metadata required to adequately describe a plant phenotyping experiment. === MIQE, Minimum Information for Publication of Quantitative Real-Time PCR Experiments === Published in 2009 these guidelines for the basis of requirements by many journals when submitting QPCR data, sadly they are not adhered to enough. === MIAME, gene expression microarray === Minimum Information About a Microarray Experiment (MIAME) describes the Minimum Information About a Microarray Experiment that is needed to enable the interpretation of the results of the experiment unambiguously and potentially to reproduce the experiment and is aimed at facilitating the dissemination of data from microarray experiments. It was published by the FGED Society in 2001 and was the first published minimum information standard for high-throughput experiments in the life sciences. MIAME contains a number of extensions to cover specific biological domains, including MIAME-env, MIAME-nut and MIAME-tox, covering environmental genomics, nutritional genomics and toxogenomics, respectively. === MINI: Minimum Information about a Neuroscience Investigation === ==== MINI: Electrophysiology ==== Electrophysiology is a technology used to study the electrical properties of biological cells and tissues. Electrophysiology typically involves the measurements of voltage change or electric current flow on a wide variety of scales from single ion channel proteins to whole tissues. This document is a single module, as part of the Minimum Information about a Neuroscience investigation (MINI) family of reporting guideline documents, produced by community consultation and continually available for public comment. A MINI module represents the minimum information that should be reported about a dataset to facilitate computational access and analysis to allow a reader to interpret and critically evaluate the processes performed and the conclusions reached, and to support their experimental corroboration. In practice a MINI module comprises a checklist of information that should be provided (for example about the protocols employed) when a data set is described for publication. The full specification of the MINI module can be found here. === MIARE, RNAi experiment === Minimum Information About an RNAi Experiment (MIARE) is a data reporting guideline which describes the minimum information that should be reported about an RNAi experiment to enable the unambiguous interpretation and reproduction of the results. === MIACA, cell based assay === Advances in genomics and functional genomics have enabled large-scale analyses of gene and protein function by means of high-throughput cell biological analyses. Thereby, cells in culture can be perturbed in vitro and the induced effects recorded and analyzed. Perturbations can be triggered in several ways, for instance with molecules (siRNAs, expression constructs, small chemical compounds, ligands for receptors, etc.), through environmental stresses (such as temperature shift, serum starvation, oxygen deprivation, etc.), or combinations thereof. The cellular responses to such perturbations are analyzed in order to identify molecular events in the biological processes addressed and understand biological principles. We propose the Minimum Information About a Cellular Assay (MIACA) for reporting a cellular assay, and CA-OM, the modular cellular assay object model, to facilitate exchange of data and accompanying information, and to compare and integrate data that originate from different, albeit complementary approaches, and to elucidate higher order principles. Documents describing MIACA are available and provide further information as well as the checklist of terms that should be reported. === MIAPE, proteomic experiments === The Minimum Information About a Proteomic Experiment documents describe information which should be given along with a proteomic experiment. The parent document describes the processes and principles underpinning the development of a series of domain specific documents which now cover all aspects of a MS-based proteomics workflow. === MIMIx, molecular interactions === This document has been developed and maintained by the Molecular Interaction worktrack of the HUPO-PSI (www.psidev.info) and describes the Minimum Information about a Molecular Interaction experiment. === MIAPAR, protein affinity reagents === The Minimum Information About a Protein Affinity Reagent has been developed and maintained by the Molecular Interaction worktrack of the HUPO-PSI (www.psidev.info)in conjunction with the HUPO Antibody Initiative and a European consortium of binder producers and seeks to encourage users to improve their description of binding reagents, such as antibodies, used in the process of protein identification. === MIABE, bioactive entities === The Minimum Information About a Bioactive Entity was produced by representatives from both large pharma and academia who are looking to improve the description of usually small molecules which bind to, and potentially modulate the activity of, specific targets in a living organism. This document encompasses drug-like molecules as well as herbicides, pesticides and food additives. It is primarily maintained through the EMBL-EBI Industry program (www.ebi.ac.uk/industry). === MIGS/MIMS, genome/metagenome sequences === This specification is being developed by the Genomic Standards Consortium === MIFlowCyt, flow cytometry === === Minimum Information about a Flow Cytometry Experiment === The Minimum Information about a Flow Cytometry Experiment (MIFlowCyt) is a standard related to flow cytometry which establishes criteria to record information on experimental overview, samples, instrumentation and data analysis. It promotes consistent annotation of clinical, biological and technical issues surrounding a flow cytometry experiment. === MINDR, dual gene expression reporters === Requires (1) reporting absolute values of reporter readouts, (2) list of positive and negative controls, and (3) sequences of all reporter constructs. === MISFISHIE, In Situ Hybridization and Immunohistochemistry Experiments === === MIAPA, Phylogenetic Analysis === Criteria for Minimum Information About a Phylogenetic Analysis were described in 2006. === MIRAGE, Glycomics === The MIRAGE project is supported and coordinated by the Beilstein-Institut to establish guidelines for data handling and processing in glycomics research [1] === MIAO, ORF === === MIAMET, METabolomics experiment === === MIAFGE, Functional Genomics Experiment === === MIRIAM, Minimum Information Required in the Annotation of Models === The Minimal Information Required In the Annotation of Models (MIRIAM), is a set of rules for the curation and annotation of quantitative models of biological systems. === MIASE, Minimum Information About a Simulation Experiment =

Odor source localization

Odor source localization (OSL) is the problem of locating the origin of an airborne or waterborne chemical plume using one or more mobile sensors, typically robots equipped with chemical sensors. The task sits at the intersection of robotics, fluid dynamics and machine olfaction. Chemical plumes in turbulent flows are intermittent and patchy, and most chemical sensors respond slowly and have limited selectivity, so the instantaneous reading available to a moving sensor is a poor proxy for the underlying time-averaged concentration field. Robotic OSL has been studied since the late 1980s and has applications including the detection of gas leaks, search and rescue after industrial accidents, and environmental monitoring of industrial emissions. == History == Robotic odor search emerged in the late 1980s and 1990s, drawing on earlier work in chemical ecology that had described how moths and other insects locate distant pheromone sources. R. A. Russell at Monash University was among the first to build mobile robots that followed chemical trails on the floor and tracked airborne odor plumes. Distributed and multi-robot odor search were investigated by Hayes, Martinoli and Goodman at the California Institute of Technology and EPFL, who studied cooperative plume-tracing on simulated and physical robot swarms. In 2007 Vergassola, Villermaux and Shraiman introduced infotaxis, an information-theoretic search strategy in which a sensor moves so as to maximize the expected information gain about source location, rather than following a chemical concentration gradient; the paper appeared in Nature and prompted substantial follow-up work in the robotics community. From the mid-2010s, multi-rotor unmanned aerial vehicles carrying lightweight chemical sensors became a common experimental platform for OSL research. == Problem formulation == OSL is generally decomposed into three sub-problems: plume detection (deciding whether a chemical signal is present), plume traversal (moving so as to remain in contact with the plume), and source declaration (deciding when the source has been reached). The mathematical difficulty depends strongly on the assumed dispersion model. In laminar or low-Reynolds number flows a Gaussian advection–diffusion model gives a smooth concentration field with a well-defined gradient. In turbulent flows, which dominate most realistic environments, the plume is filamentary: the sensor receives short, randomly spaced bursts of chemical separated by periods of zero signal, and the time-averaged field is not a useful guide on the time scales at which a robot must act. Source-term estimation, surveyed by Hutchinson and colleagues, additionally aims to recover both the position and the release rate of the source from the observed concentrations, often using probabilistic filters. == Biological inspiration == Many OSL strategies are explicitly modeled on the behavior of male moths flying upwind toward a pheromone source. As reviewed by Cardé and Willis, moths combine an upwind surge whenever they detect a filament of pheromone with a wider crosswind cast when contact is lost, producing a characteristic zig-zag trajectory that has been transposed onto mobile robots by several groups. Other biological models draw on the search behavior of dogs and of marine animals such as blue crabs and lobsters, which integrate chemical and bilateral hydrodynamic cues over much shorter ranges. == Algorithms and strategies == === Reactive strategies === Reactive strategies select the next motion as a direct function of the current sensor reading. Chemotaxis steers along the locally estimated concentration gradient, which is effective in laminar plumes but degrades severely in turbulence. Anemotaxis exploits a measured wind direction by surging upwind when chemical contact is made. The bio-inspired cast-and-surge family combines anemotaxis with a deterministic crosswind cast on contact loss, and is the dominant reactive approach for turbulent environments. === Probabilistic and information-theoretic strategies === Probabilistic methods maintain a posterior distribution over possible source locations and choose actions that improve that distribution. The infotaxis strategy of Vergassola, Villermaux and Shraiman selects the move that maximizes the expected reduction in entropy of the source-location posterior, and is effective in regimes where the spatial gradient is unusable. Bayesian source-term estimation extends this idea by inferring both source position and release rate, typically using particle filters or sequential Monte Carlo. === Map-based strategies === Map-based methods build a spatial model of the time-averaged gas distribution from sensor readings collected along the robot's trajectory and search for local maxima in that model. Lilienthal and colleagues describe a family of kernel-based gas distribution mapping techniques in which point measurements are convolved with a Gaussian kernel to produce a spatially extrapolated estimate. Such methods are most useful when the source can be assumed quasi-stationary and the robot is able to revisit locations. === Multi-robot and swarm strategies === Multiple robots searching cooperatively can shorten search times. Cooperative formations spread the sensors across the crosswind axis, making detection of an intermittent plume more likely. Swarm-based approaches, reviewed by Wang and colleagues, deploy larger numbers of simpler agents and rely on collective behavior rather than centralized planning; reported advantages include improved coverage of the search area and the possibility of locating multiple sources in parallel. == Sensors and platforms == Most OSL systems use metal-oxide semiconductor (MOX) sensors, photoionization detectors or electrochemical cells, which trade off sensitivity, selectivity, response time and power consumption. Ishida and colleagues describe how these sensors interact with airflow around the robot body, an effect that motivates careful aerodynamic design and active sampling. Mobile platforms include wheeled ground robots for indoor and structured outdoor environments, multi-rotor unmanned aerial vehicles for open spaces and elevated sources, and autonomous underwater vehicles for chemical plumes in the marine environment. == Notable systems == Among the early demonstrations, R. A. Russell's series of differential-drive robots at Monash University localized volatile sources in still and ventilated rooms during the 1990s. The Smelling Nano Aerial Vehicle reported by Burgués and colleagues used a Crazyflie nano-quadcopter (approximately 27 grams in mass and 10 cm across) carrying a custom MOX gas sensing board, and built three-dimensional gas distribution maps of indoor releases from sweeping flights of less than three minutes. The GADEN simulator, released by Monroy and colleagues, couples three-dimensional dispersion computed from an OpenFOAM CFD solver with models of MOX and photo-ionization gas sensors, and is widely used to test mobile-robot olfaction algorithms in simulation. == Applications == Reported applications include the localization of natural-gas and methane leaks in urban infrastructure, search for chemical contamination after industrial accidents, search and rescue, and environmental monitoring of industrial emissions. Drug- and explosives-detection robots are an adjacent application area, although these typically rely on close-range sniffing rather than long-range plume tracking. == Open challenges == Open challenges identified in recent reviews include the limited speed, selectivity and stability of available chemical sensors; the scarcity of standardized, large-scale benchmarks comparable to those available in computer vision; reliable handling of multi-source environments, where standard single-source assumptions fail; and the integration of OSL with other autonomous-vehicle subsystems such as obstacle avoidance and navigation in three-dimensional turbulent flow.

Phase stretch transform

Phase stretch transform (PST) is a computational approach to signal and image processing. One of its utilities is for feature detection and classification. PST is related to time stretch dispersive Fourier transform. It transforms the image by emulating propagation through a diffractive medium with engineered 3D dispersive property (refractive index). The operation relies on symmetry of the dispersion profile and can be understood in terms of dispersive eigenfunctions or stretch modes. PST performs similar functionality as phase-contrast microscopy, but on digital images. PST can be applied to digital images and temporal (time series) data. It is a physics-based feature engineering algorithm. == Operation principle == Here the principle is described in the context of feature enhancement in digital images. The image is first filtered with a spatial kernel followed by application of a nonlinear frequency-dependent phase. The output of the transform is the phase in the spatial domain. The main step is the 2-D phase function which is typically applied in the frequency domain. The amount of phase applied to the image is frequency dependent, with higher amount of phase applied to higher frequency features of the image. Since sharp transitions, such as edges and corners, contain higher frequencies, PST emphasizes the edge information. Features can be further enhanced by applying thresholding and morphological operations. PST is a pure phase operation whereas conventional edge detection algorithms operate on amplitude. == Physical and mathematical foundations of phase stretch transform == Photonic time stretch technique can be understood by considering the propagation of an optical pulse through a dispersive fiber. By disregarding the loss and non-linearity in fiber, the non-linear Schrödinger equation governing the optical pulse propagation in fiber upon integration reduces to: E o ( z , t ) = 1 2 π ∫ − ∞ ∞ E ~ i ( 0 , ω ) ⋅ e − i β 2 z ω 2 2 ⋅ e i ω t d ω {\displaystyle E_{o}(z,t)={\frac {1}{2\pi }}\int _{-\infty }^{\infty }{\tilde {E}}_{i}(0,\omega )\cdot e^{\frac {-i\beta _{2}z\omega ^{2}}{2}}\cdot e^{i\omega {t}}\,d\omega } (1) where β 2 {\displaystyle \beta _{2}} = GVD parameter, z is propagation distance, E o ( z , t ) {\displaystyle E_{o}(z,t)} is the reshaped output pulse at distance z and time t. The response of this dispersive element in the time-stretch system can be approximated as a phase propagator as presented in H ( ω ) = e i φ ( ω ) = e i ∑ m = 0 ∞ φ m ( ω ) = ∏ m = 0 ∞ H m ( ω ) {\displaystyle H(\omega )=e^{i\varphi (\omega )}=e^{i\sum _{m=0}^{\infty }\varphi _{m}(\omega )}=\prod _{m=0}^{\infty }H_{m}(\omega )} (2) Therefore, Eq. 1 can be written as following for a pulse that propagates through the time-stretch system and is reshaped into a temporal signal with a complex envelope given by E o ( t ) = 1 2 π ∫ − ∞ ∞ E ~ i ( ω ) ⋅ H ( ω ) ⋅ e i ω t d ω {\displaystyle E_{o}(t)={\frac {1}{2\pi }}\int _{-\infty }^{\infty }{\tilde {E}}_{i}(\omega )\cdot H(\omega )\cdot e^{i\omega t}\,d\omega } (3) The time stretch operation is formulated as generalized phase and amplitude operations, S { E i ( t ) } = ∫ − ∞ + ∞ F { E i ( t ) } ⋅ e i φ ( ω ) ⋅ L ~ ( ω ) ⋅ e i ω t d ω {\displaystyle \mathbb {S} \{E_{i}(t)\}=\int _{-\infty }^{+\infty }{\mathcal {F}}\{E_{i}(t)\}\cdot e^{i\varphi (\omega )}\cdot {\tilde {L}}(\omega )\cdot e^{i\omega {t}}d\omega } (4) where e i φ ( ω ) {\displaystyle e^{i\varphi (\omega )}} is the phase filter and L ~ ( ω ) {\displaystyle {\tilde {L}}(\omega )} is the amplitude filter. Next the operator is converted to discrete domain, S { E i [ n ] } = 1 N ∑ u = 0 N − 1 F F T { E i ( n ) } ⋅ K ~ ( u ) ⋅ L ~ ( u ) ⋅ e i 2 π N u n {\displaystyle \mathbb {S} \{E_{i}[n]\}={\frac {1}{N}}\sum _{u=0}^{N-1}FFT\{E_{i}(n)\}\cdot {\tilde {K}}(u)\cdot {\tilde {L}}(u)\cdot e^{i{\frac {2\pi }{N}}un}} (5) where u {\displaystyle u} is the discrete frequency, K ~ ( u ) {\displaystyle {\tilde {K}}(u)} is the phase filter, L ~ ( u ) {\displaystyle {\tilde {L}}(u)} is the amplitude filter and FFT is fast Fourier transform. The stretch operator S { } {\displaystyle \mathbb {S} \{\}} for a digital image is then S { E i [ n , m ] } = 1 M N ∑ v = 0 N − 1 ∑ u = 0 M − 1 F F T 2 { E i ( n , m ) } ⋅ K ~ ( u , v ) ⋅ L ~ ( u , v ) ⋅ e i 2 π M u m ⋅ e i 2 π N v n {\displaystyle \mathbb {S} \{E_{i}[n,m]\}={\frac {1}{MN}}\sum _{v=0}^{N-1}\sum _{u=0}^{M-1}FFT^{2}\{E_{i}(n,m)\}\cdot {\tilde {K}}(u,v)\cdot {\tilde {L}}(u,v)\cdot e^{i{\frac {2\pi }{M}}um}\cdot e^{i{\frac {2\pi }{N}}vn}} (6) In the above equations, E i [ n , m ] {\displaystyle E_{i}[n,m]} is the input image, n {\displaystyle n} and m {\displaystyle m} are the spatial variables, F F T 2 {\displaystyle FFT^{2}} is the two-dimensional fast Fourier transform, and u {\displaystyle u} and v {\displaystyle v} are spatial frequency variables. The function K ~ ( u , v ) {\displaystyle {\tilde {K}}(u,v)} is the warped phase kernel and the function L ~ ( u , v ) {\displaystyle {\tilde {L}}(u,v)} is a localization kernel implemented in frequency domain. PST operator is defined as the phase of the Warped Stretch Transform output as follows P S T { E i [ n , m ] } ≜ ∡ { S { E i [ x , y ] } } {\displaystyle PST\{E_{i}[n,m]\}\triangleq \measuredangle \{\mathbb {S} \{E_{i}[x,y]\}\}} (7) where ∡ { } {\displaystyle \measuredangle \{\}} is the angle operator. == PST kernel implementation == The warped phase kernel K ~ ( u , v ) {\displaystyle {\tilde {K}}(u,v)} can be described by a nonlinear frequency dependent phase K ~ ( u , v ) = e i φ ( u , v ) {\displaystyle {\tilde {K}}(u,v)=e^{i\varphi (u,v)}} While arbitrary phase kernels can be considered for PST operation, here we study the phase kernels for which the kernel phase derivative is a linear or sublinear function with respect to frequency variables. A simple example for such phase derivative profiles is the inverse tangent function. Consider the phase profile in the polar coordinate system φ ( u , v ) = φ polar ( r , θ ) = φ polar ( r ) {\displaystyle \varphi (u,v)=\varphi _{\text{polar}}(r,\theta )=\varphi _{\text{polar}}(r)} From d φ ( r ) d r = tan − 1 ⁡ ( r ) {\displaystyle {\frac {d\varphi (r)}{dr}}=\tan ^{-1}(r)} we have φ ( r ) = r tan − 1 ⁡ ( r ) − 1 2 log ⁡ ( r 2 + 1 ) {\displaystyle \varphi (r)=r\tan ^{-1}(r)-{\frac {1}{2}}\log(r^{2}+1)} Therefore, the PST kernel is implemented as φ ( r ) = S ⋅ ( W r ) ⋅ tan − 1 ⁡ ( W r ) − 1 2 log ⁡ ( 1 + ( W r ) 2 ) ( W r max ) ⋅ tan − 1 ⁡ ( W r max ) − 1 2 log ⁡ ( 1 + ( W r max ) 2 ) {\displaystyle \varphi (r)=S\cdot {\frac {(Wr)\cdot \tan ^{-1}(Wr)-{\frac {1}{2}}\log(1+(Wr)^{2})}{(Wr_{\max })\cdot \tan ^{-1}(Wr_{\max })-{\frac {1}{2}}\log(1+(Wr_{\max })^{2})}}} where S {\displaystyle S} and W {\displaystyle W} are real-valued numbers related to the strength and warp of the phase profile == Applications == PST has been used for edge detection in biological and biomedical images as well as synthetic-aperture radar (SAR) image processing, as well as detail and feature enhancement for digital images. PST has also been applied to improve the point spread function for single molecule imaging in order to achieve super-resolution. The transform exhibits intrinsic superior properties compared to conventional edge detectors for feature detection in low contrast visually impaired images. The PST function can also be performed on 1-D temporal waveforms in the analog domain to reveal transitions and anomalies in real time. == Open source code release == On February 9, 2016, a UCLA Engineering research group has made public the computer code for PST algorithm that helps computers process images at high speeds and "see" them in ways that human eyes cannot. The researchers say the code could eventually be used in face, fingerprint, and iris recognition systems for high-tech security, as well as in self-driving cars' navigation systems or for inspecting industrial products. The Matlab implementation for PST can also be downloaded from Matlab Files Exchange. However, it is provided for research purposes only, and a license must be obtained for any commercial applications. The software is protected under a US patent. The code was then significantly refactored and improved to support GPU acceleration. In May 2022, it became one algorithm in PhyCV: the first physics-inspired computer vision library.

Voice activity detection

Voice activity detection (VAD), also known as speech activity detection or speech detection, is the detection of the presence or absence of human speech, used in speech processing. The main uses of VAD are in speaker diarization, speech coding and speech recognition. It can facilitate speech processing, and can also be used to deactivate some processes during non-speech section of an audio session: it can avoid unnecessary coding/transmission of silence packets in Voice over Internet Protocol (VoIP) applications, saving on computation and on network bandwidth. VAD is an important enabling technology for a variety of speech-based applications. Therefore, various VAD algorithms have been developed that provide varying features and compromises between latency, sensitivity, accuracy and computational cost. Some VAD algorithms also provide further analysis, for example whether the speech is voiced, unvoiced or sustained. Voice activity detection is usually independent of language. It was first investigated for use on time-assignment speech interpolation (TASI) systems. == Algorithm overview == The typical design of a VAD algorithm is as follows: There may first be a noise reduction stage, e.g. via spectral subtraction. Then some features or quantities are calculated from a section of the input signal. A classification rule is applied to classify the section as speech or non-speech – often this classification rule finds when a value exceeds a certain threshold. There may be some feedback in this sequence, in which the VAD decision is used to improve the noise estimate in the noise reduction stage, or to adaptively vary the threshold(s). These feedback operations improve the VAD performance in non-stationary noise (i.e. when the noise varies a lot). A representative set of recently published VAD methods formulates the decision rule on a frame by frame basis using instantaneous measures of the divergence distance between speech and noise. The different measures which are used in VAD methods include spectral slope, correlation coefficients, log likelihood ratio, cepstral, weighted cepstral, and modified distance measures. Independently from the choice of VAD algorithm, a compromise must be made between having voice detected as noise, or noise detected as voice (between false positive and false negative). A VAD operating in a mobile phone must be able to detect speech in the presence of a range of very diverse types of acoustic background noise. In these difficult detection conditions it is often preferable that a VAD should fail-safe, indicating speech detected when the decision is in doubt, to lower the chance of losing speech segments. The biggest difficulty in the detection of speech in this environment is the very low signal-to-noise ratios (SNRs) that are encountered. It may be impossible to distinguish between speech and noise using simple level detection techniques when parts of the speech utterance are buried below the noise. == Applications == VAD is an integral part of different speech communication systems such as audio conferencing, echo cancellation, speech recognition, speech encoding, speaker recognition and hands-free telephony. In the field of multimedia applications, VAD allows simultaneous voice and data applications. Similarly, in Universal Mobile Telecommunications Systems (UMTS), it controls and reduces the average bit rate and enhances overall coding quality of speech. In cellular radio systems (for instance GSM and CDMA systems) based on Discontinuous Transmission (DTX) mode, VAD is essential for enhancing system capacity by reducing co-channel interference and power consumption in portable digital devices. In speech processing applications, voice activity detection plays an important role since non-speech frames are often discarded. For a wide range of applications such as digital mobile radio, Digital Simultaneous Voice and Data (DSVD) or speech storage, it is desirable to provide a discontinuous transmission of speech-coding parameters. Advantages can include lower average power consumption in mobile handsets, higher average bit rate for simultaneous services like data transmission, or a higher capacity on storage chips. However, the improvement depends mainly on the percentage of pauses during speech and the reliability of the VAD used to detect these intervals. On the one hand, it is advantageous to have a low percentage of speech activity. On the other hand, clipping, that is the loss of milliseconds of active speech, should be minimized to preserve quality. This is the crucial problem for a VAD algorithm under heavy noise conditions. === Use in telemarketing === One controversial application of VAD is in conjunction with predictive dialers used by telemarketing firms. In order to maximize agent productivity, telemarketing firms set up predictive dialers to call more numbers than they have agents available, knowing most calls will end up in either "Ring – No Answer" or answering machines. When a person answers, they typically speak briefly ("Hello", "Good evening", etc.) and then there is a brief period of silence. Answering machine messages are usually 3–15 seconds of continuous speech. By setting VAD parameters correctly, dialers can determine whether a person or a machine answered the call and, if it's a person, transfer the call to an available agent. If it detects an answering machine message, the dialer hangs up. Often, even when the system correctly detects a person answering the call, no agent may be available, resulting in a "silent call". Call screening with a multi-second message like "please say who you are, and I may pick up the phone" will frustrate such automated calls. == Performance evaluation == To evaluate a VAD, its output using test recordings is compared with those of an "ideal" VAD – created by hand-annotating the presence or absence of voice in the recordings. The performance of a VAD is commonly evaluated on the basis of the following four parameters: FEC (Front End Clipping): clipping introduced in passing from noise to speech activity; MSC (Mid Speech Clipping): clipping due to speech misclassified as noise; OVER: noise interpreted as speech due to the VAD flag remaining active in passing from speech activity to noise; NDS (Noise Detected as Speech): noise interpreted as speech within a silence period. Although the method described above provides useful objective information concerning the performance of a VAD, it is only an approximate measure of the subjective effect. For example, the effects of speech signal clipping can at times be hidden by the presence of background noise, depending on the model chosen for the comfort noise synthesis, so some of the clipping measured with objective tests is in reality not audible. It is therefore important to carry out subjective tests on VADs, the main aim of which is to ensure that the clipping perceived is acceptable. In VoIP applications, front-end clipping can be reduced by rewinding to shortly before the detection and sending very slightly delayed data. This kind of test requires a certain number of listeners to judge recordings containing the processing results of the VADs being tested, giving marks to several speech sequences on the following features: Quality; Comprehension difficulty; Audibility of clipping. These marks are then used to calculate average results for each of the features listed above, thus providing a global estimate of the behavior of the VAD being tested. To conclude, whereas objective methods are very useful in an initial stage to evaluate the quality of a VAD, subjective methods are more significant. As they require the participation of several people for a few days, increasing cost, they are generally only used when a proposal is about to be standardized. == Implementations == One early standard VAD is that developed by British Telecom for use in the Pan-European digital cellular mobile telephone service in 1991. It uses inverse filtering trained on non-speech segments to filter out background noise, so that it can then more reliably use a simple power-threshold to decide if a voice is present. The G.729 standard calculates the following features for its VAD: line spectral frequencies, full-band energy, low-band energy (<1 kHz), and zero-crossing rate. It applies a simple classification using a fixed decision boundary in the space defined by these features, and then applies smoothing and adaptive correction to improve the estimate. The GSM standard includes two VAD options developed by ETSI. Option 1 computes the SNR in nine bands and applies a threshold to these values. Option 2 calculates different parameters: channel power, voice metrics, and noise power. It then thresholds the voice metrics using a threshold that varies according to the estimated SNR. The Speex audio compression library uses a procedure named Improved Minima Controlled Recursive Averaging, which uses a smoothed representation of spectral pow

AVS Video Editor

AVS Video Editor is a video editing software published by Online Media Technologies Ltd. It is a part of AVS4YOU software suite which includes video, audio, image editing and conversion, disc editing and burning, document conversion and registry cleaner programs. It offers the opportunity to create and edit videos with a vast variety of video and audio effects, text and transitions; capture video from screen, web or DV cameras and VHS tape; record voice; create menus for discs, as well as to save them to plenty of video file formats, burn to discs or publish on Facebook, YouTube, Flickr, etc. == Description == === Interface === The layout consists of the timeline or storyboard view, preview pane and media library (transitions, video effects, text or disc menus) collections. The storyboard view shows the sequence of video clips with the transitions between them and used to change the order of clips or add transitions. Timeline view consists of main video, audio, effects, video overlay and text lines for editing. Once on the timeline video can be duplicated, split, muted, frozen, cropped, stabilized, its speed can be slowed down or increased, audio and color corrected. === Importing footage === Video, audio and image files necessary for video project can be imported into the program from computer hard disk drive. User can also capture video from computer screen, web or mini DV camera, as well as from VHS tape, record voice. === Output (web, device, disc, format) === AVS Video Editor gives the opportunity to save video to a computer hard drive to one of the video formats: AVI, DVD, Blu-ray, MOV, MP4, M4V, MPEG, WMV, MKV, WebM, M2TS, TS, FLV, SWF, RM, 3GP, GIF, DPG, AMV, MTV; burn to DVD or Blu-ray disc with menus; create a video for mobile players, mobile phones or gaming consoles and upload it right to the device. The most popular devices such as Apple iPod, Apple iPhone, Apple iPad, Sony PSP, Samsung Galaxy, Android and BlackBerry smartphones and tablets are supported. There is also an option to create a video that can be streamed via web and save it into Flash or WebM format or for the popular web services: YouTube, Facebook, Telly (Twitvid), Dailymotion, Flickr and Dropbox. === Features === Single and multithread modes: if a computer supports multi-threading, video creation process is performed faster in multithread mode, especially on a multi-core system. Customization of the output file settings, such as bitrate, frame rate, frame size, video and audio codecs, etc. Transitions - help video clips smoothly go into one another, dissolve or overlap two video or image files. Fade in and fade out video and audio files - dissolve a video to and from a blank image, reduce the audio volume at the end of the video and increase at the beginning. Slideshow creation - create a presentation of a series of still images. Voice recording Projects - once a project is created and saved, the next time saving video to some other format will be fast, projects are also used if a user do not have a possibility to create, edit and save video all at once. Video overlay option - superpose video image over the video clip that is being edited. Disk menu and chapters creation - an option for DVD and Blu-ray video. Freeze frame - make a still shot from a video clip. Stabilization feature - reduce jittering or blurring caused by shaky motions of a camera. Enhanced deinterlacing method - increase video quality for interlaced input file - spots and blurred areas are compensated. Scene detection - search and separate one scene of the video from the other. Loop DVD and SWF - output SWF and DVD video are played back continuously. Caching for processing high definition files - create a duplicate video file smaller in size to use it on the preview window and accelerate processing of HD files. Chroma key option - add video overlay half transparent so that only part of it is visible and all the rest disappears to reveal the video underneath. Capture video material from DV tapes, VHS tapes, web cameras, etc. Movie closing credits - add information on movie editing, e.g. crew, cast, data, etc. Creeping line, subtitles, text - add different captions (static and animated), shapes and images to video. Speech balloons and other graphic objects - geometrical shapes to highlight an object in the video. Zoom effect - magnify or reduce the view of the image. Rotate effect - rotate video image at different degrees, e.g. 90, 180, etc. Grayscale and old movie effects - create a black and white video image. Old movie adds also scratches, noise, shake and dust to video, as if it's being played on an old projector. Blur and sharpen effects - visually smooth and soften an image, or make video image better focused. Snow and particles effects - adds snow or various objects (bubbles, flowers, leaves, butterflies etc.) that are moving, flying or falling on the video. Pan and zoom Timer, countdown effects - add a timepiece that measures or counts down a time interval to the video being edited. Snapshots - capture a particular moment of a video clip. Sound track replacement - mute audio track from video and add another one. Audio amplify, noise removal, equalizer, etc. - make video sound louder, attenuate the noise, change frequency pattern of the audio, make some other audio adjustments. Trim and multi-trim options - change video clip duration cutting out unnecessary parts or detect scenes and cut out parts in any place of the video clip. Color correction (brightness, temperature, contrast, saturation, gamma, etc.) effects - allow adjustment of tonal range, color, and sharpness of video files. Crop scale effect - get rid of mattes that appear after changing aspect ratio of a video file. Adjusting the Playback Speed Volume and balance - change sound volume in the output video. Change volume value proportion for main video and added soundtrack, completely mute main video audio and leave added soundtrack only, etc. === Utilities embedded into AVS Video Editor === AVS Mobile Uploader is used to transfer edited and converted media files to portable devices via Bluetooth, Infrared or USB connection. AVS Video Burner is used to burn converted video files to different disc types: CD, DVD, Blu-ray. AVS Video Recorder is used to capture video from analog video sources and supports different types of devices: capture card, web camera (webcam), DV camera, HDV camera. AVS Video Uploader is used to transfer video files to popular video-sharing websites, like Facebook, Dailymotion, YouTube, Photobucket, TwitVid, MySpace, Flickr. AVS Screen Capture is used to capture any actions on the desktop to make presentations or video tutorials more vivid and easily comprehensible. == Important upgrades == The initial release of AVS Video Editor was in 2003 when the program was offered inside AVS software bundles together with AVS Video Tools, AVS Audio Tools and DVD Copy software. In 2005 the program is offered as a part of multifunctional AVS4YOU software suite. AVS Video Editor is frequently updated. The main updates include adding several important features for video editing

Automatic meter reading

Automatic meter reading (AMR) is the technology of automatically collecting consumption, diagnostic, and status data from water meter or energy metering devices (gas, electric) and transferring that data to a central database for billing, troubleshooting, and analyzing. This technology mainly saves utility providers the expense of periodic trips to each physical location to read a meter. Another advantage is that billing can be based on near real-time consumption rather than on estimates based on past or predicted consumption. This timely information coupled with analysis can help both utility providers and customers better control the use and production of electric energy, gas usage, or water consumption. AMR technologies include handheld, mobile and network technologies based on telephony platforms (wired and wireless), radio frequency (RF), or powerline transmission. == Technologies == === Touch technology === With touch-based AMR, a meter reader carries a handheld computer or data collection device with a wand or probe. The device automatically collects the readings from a meter by touching or placing the read probe close to a reading coil enclosed in the touchpad. When a button is pressed, the probe sends an interrogate signal to the touch module to collect the meter reading. The software in the device matches the serial number to one in the route database, and saves the meter reading for later download to a billing or data collection computer. Since the meter reader still has to go to the site of the meter, this is sometimes referred to as "on-site" AMR. Another form of contact reader uses a standardized infrared port to transmit data. Protocols are standardized between manufacturers by such documents as ANSI C12.18 or IEC 61107. === AMR hosting === AMR hosting is a back-office solution which allows a user to track their electricity, water, or gas consumption over the Internet. All data is collected in near real-time, and is stored in a database by data acquisition software. The user can view the data via a web application, and can analyze the data using various online analysis tools such as charting load profiles, analyzing tariff components, and verify their utility bill. === Radio frequency network === Radio frequency based AMR can take many forms. The more common ones are handheld, mobile, satellite and fixed network solutions. There are both two-way RF systems and one-way RF systems in use that use both licensed and unlicensed RF bands. In a two-way or "wake up" system, a radio signal is normally sent to an AMR meter's unique serial number, instructing its transceiver to power-up and transmit its data. The meter transceiver and the reading transceiver both send and receive radio signals. In a one-way "bubble-up" or continuous broadcast type system, the meter transmits continuously and data is sent every few seconds. This means the reading device can be a receiver only, and the meter a transmitter only. Data travels only from the meter transmitter to the reading receiver. There are also hybrid systems that combine one-way and two-way techniques, using one-way communication for reading and two-way communication for programming functions. RF-based meter reading usually eliminates the need for the meter reader to enter the property or home, or to locate and open an underground meter pit. The utility saves money by increased speed of reading, has less liability from entering private property, and has fewer missed readings from being unable to access the meter. The technology based on RF is not readily accepted everywhere. In several Asian countries, the technology faces a barrier of regulations in place pertaining to use of the radio frequency of any radiated power. For example, in India the radio frequency which is generally in ISM band is not free to use even for low power radio of 10 mW. The majority of manufacturers of electricity meters have radio frequency devices in the frequency band of 433/868 MHz for large scale deployment in European countries. The frequency band of 2.4 GHz can be now used in India for outdoor as well as indoor applications, but few manufacturers have shown products within this frequency band. Initiatives in radio frequency AMR in such countries are being taken up with regulators wherever the cost of licensing outweighs the benefits of AMR. ==== Handheld ==== In handheld AMR, a meter reader carries a handheld computer with a built-in or attached receiver/transceiver (radio frequency or touch) to collect meter readings from an AMR capable meter. This is sometimes referred to as "walk-by" meter reading since the meter reader walks by the locations where meters are installed as they go through their meter reading route. Handheld computers may also be used to manually enter readings without the use of AMR technology as an alternate but this will not support exhaustive data which can be accurately read using the meter reading electronically. ==== Mobile ==== Mobile or "drive-by" meter reading is where a reading device is installed in a vehicle. The meter reader drives the vehicle while the reading device automatically collects the meter readings. Often, for mobile meter reading, the reading equipment includes navigational and mapping features provided by GPS and mapping software. With mobile meter reading, the reader does not normally have to read the meters in any particular route order, but just drives the service area until all meters are read. Components often consist of a laptop or proprietary computer, software, RF receiver/transceiver, and external vehicle antennas. ==== Satellite ==== Transmitters for data collection satellites can be installed in the field next to existing meters. The satellite AMR devices communicate with the meter for readings, and then sends those readings over a fixed or mobile satellite network. This network requires a clear view to the sky for the satellite transmitter/receiver, but eliminates the need to install fixed towers or send out field technicians, thereby being particularly suited for areas with low geographic meter density. ==== RF technologies commonly used for AMR ==== Narrow Band (single fixed radio frequency) Spread spectrum Direct-sequence spread spectrum (DSSS) Frequency-hopping spread spectrum (FHSS) There are also meters using AMR with RF technologies such as cellular phone data systems, Zigbee, Bluetooth, Wavenis and others. Some systems operate with U.S. Federal Communications Commission (FCC) licensed frequencies and others under FCC Part 15, which allows use of unlicensed radio frequencies. ==== Wi-Fi ==== WiSmart is a versatile platform which can be used by a variety of electrical home appliances in order to provide wireless TCP/IP communication using the 802.11 b/g protocol. Devices such as the Smart Thermostat permit a utility to lower a home's power consumption to help manage power demand. The city of Corpus Christi became one of the first cities in the United States to implement citywide Wi-Fi, which had been free until May 31, 2007, mainly to facilitate AMR after a meter reader was attacked by a dog. Today many meters are designed to transmit using Wi-Fi, even if a Wi-Fi network is not available, and they are read using a drive-by local Wi-Fi hand held receiver. The meters installed in Corpus Christi are not directly Wi-Fi enabled, but rather transmit narrow-band burst telemetry on the 460 MHz band. This narrow-band signal has much greater range than Wi-Fi, so the number of receivers required for the project are far fewer. Special receiver stations then decode the narrow-band signals and resend the data via Wi-Fi. Most of the automated utility meters installed in the Corpus Christi area are battery powered. Wi-Fi technology is unsuitable for long-term battery-powered operation. === Power line communication === PLC is a method where electronic data is transmitted over power lines back to the substation, then relayed to a central computer in the utility's main office. This would be considered a type of fixed network system—the network being the distribution network which the utility has built and maintains to deliver electric power. Such systems are primarily used for electric meter reading. Some providers have interfaced gas and water meters to feed into a PLC type system. == Brief history == In 1972, Theodore George "Ted" Paraskevakos, while working with Boeing in Huntsville, Alabama, developed a sensor monitoring system which used digital transmission for security, fire and medical alarm systems as well as meter reading capabilities for all utilities. This technology was a spin-off of the automatic telephone line identification system, now known as caller ID. In 1974, Paraskevakos was awarded a U.S. patent for this technology. In 1977, he launched Metretek, Inc., which developed and produced the first fully automated, commercially available remote meter reading and load management system. Since this system was developed pre-Internet, Metret

Paint.NET

Paint.NET (sometimes stylized as paint.net) is a freeware general-purpose raster graphics editor program for Microsoft Windows, developed with the .NET platform. Paint.NET was originally created by Rick Brewster as a Washington State University student project, and has evolved from a simple replacement for the Microsoft Paint program into a program for editing mainly graphics, with support for plugins. == History == Paint.NET originated as a computer science senior design project by Rick Brewster during spring 2004 at Washington State University. Version 1.0 consisted of 36,000 lines of code and was written in four months. In contrast, version 3.35 has approximately 162,000 lines of code. The Paint.NET project continued over the summer and into the autumn 2004 semester for both the version 1.1 and 2.0 releases. Development continued with one programmer who worked on previous versions of Paint.NET while he was a student at WSU. As of May 2006 the program had been downloaded at least 2 million times, at a rate of about 180,000 per month. Initially, Paint.NET was released under a modified version of the MIT License, with the exclusion of the installer, text, and graphics. However, citing issues with the open source code being plagiarized by others that had rebranded the software as their own and bundled user content without their permission, the availability of the source code was restricted, in December 2007 Brewster announced his intent to restrict access to components of the program (including its installer, resources, and user interface). In November 2009, the software was made proprietary, restricting the sale or creation of derivative works of the software. Starting with version 4.0.18, Paint.NET is published in two editions: A classic edition remains freeware, similar to all other versions since 3.5. Another edition, however, is published to Microsoft Store under a trialware license and is available to purchase for US$14.99. According to the developer, this was done to enable the users to contribute to the development with more convenience, even though the old avenue of donation was not closed. In May 2026, Brewster revealed that he obtained the paint.net domain after attempting to do so for 22 years. Historically, the editor was hosted on getpaint.net, and according to Brewster, the previous owners of paint.net would not sell the domain and asked for "lots and lots of money". In December of the previous year, paint.net began hosting content that impersonated Paint.NET, therefore becoming a clear case of trademark infringement and domain squatting. Brewster stated that he was able to obtain the domain afterwards with the help of a lawyer. == Overview == Paint.NET is primarily programmed in the C# programming language. Its native image format, .PDN, is a compressed representation of the application's internal object format, which preserves layering and other information. == Plugins == Paint.NET supports plugins, which add image adjustments, effects, and support for additional file types. They can be programmed using any .NET Framework programming language, though they are most commonly written in C#. These are created by volunteer coders on the program's discussion board, the Paint.NET Forum. Though most are simply published via the discussion board, some have been included with a later release of the program. For instance, a DirectDraw Surface file type plugin, (originally by Dean Ashton) and an Ink Sketch and Soften Portrait effect (originally by David Issel) were added to Paint.NET in version 3.10. Hundreds of plugins have been produced; such as Shape3D, which renders a 2D drawing into a 3D shape. Some plugins expand on the functionality that comes with Paint.NET, such as Curves+ and Sharpen+, which extend the included tools Curves and Sharpen, respectively. Examples of file type plugins include an Animated Cursor and Icon plugin and an Adobe Photoshop file format plugin. Several of these plugins are based on existing open source software, such as a raw image format plugin that uses dcraw and a PNG optimization plugin that uses OptiPNG. == Forks == === paint-mono === Paint.NET was created exclusively for Windows and has no native support for other operating systems. Due to its former open-source licensing, the development of alternative versions was possible. In May 2007, Miguel de Icaza officially started a porting project called paint-mono. This project had partially ported Paint.NET 3.0 to Mono, an open-source implementation of the Common Language Infrastructure on which the .NET Framework is based. This allowed Paint.NET to be run on Mono-supported platforms, such as Linux. This port is no longer maintained and has not been updated since March 2009. Newer Mono runtime 6 versions are able to run original Paint.NET releases up to 3.5.11 with only minor issues. === Pinta === In 2010, developer Jonathan Pobst started a project called Pinta, describing it as a clone of Paint.NET for Mono and Gtk#. Pinta reused the adjustments and effects code from Paint.NET but otherwise is original code.