A GeneRIF or Gene Reference Into Function is a short (255 characters or fewer) statement about the function of a gene. GeneRIFs provide a simple mechanism for allowing scientists to add to the functional annotation of genes described in the Entrez Gene database. In practice, function is constructed quite broadly. For example, there are GeneRIFs that discuss the role of a gene in a disease, GeneRIFs that point the viewer towards a review article about the gene, and GeneRIFs that discuss the structure of a gene. However, the stated intent is for GeneRIFs to be about gene function. Currently over half a million geneRIFs have been created for genes from almost 1000 different species. GeneRIFs are always associated with specific entries in the Entrez Gene database. Each GeneRIF has a pointer to the PubMed ID (a type of document identifier) of a scientific publication that provides evidence for the statement made by the GeneRIF. GeneRIFs are often extracted directly from the document that is identified by the PubMed ID, very frequently from its title or from its final sentence. GeneRIFs are usually produced by NCBI indexers, but anyone may submit a GeneRIF. To be processed, a valid Gene ID must exist for the specific gene, or the Gene staff must have assigned an overall Gene ID to the species. The latter case is implemented via records in Gene with the symbol NEWENTRY. Once the Gene ID is identified, only three types of information are required to complete a submission: a concise phrase describing a function or functions (less than 255 characters in length, preferably more than a restatement of the title of the paper); a published paper describing that function, implemented by supplying the PubMed ID of a citation in PubMed; a valid e-mail address (which will remain confidential). == Example == Here are some GeneRIFs taken from Entrez Gene for GeneID 7157, the human gene TP53. The PubMed document identifiers have been omitted from the examples. Note the wide variability with respect to the presence or absence of punctuation and of sentence-initial capital letters. p53 and c-erbB-2 may have independent role in carcinogenesis of gall bladder cancer Degradation of endogenous HIPK2 depends on the presence of a functional p53 protein. p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1 Logistic regression analysis showed p53 and COX-2 as dependent predictors in pancreatic carcinogenesis, and a reciprocal relationship to neoplastic progression between p53 and COX-2. GeneRIFs are an unusual type of textual genre, and they have recently been the subject of a number of articles from the natural language processing community.
Intelligent control
Intelligent control is a class of control techniques that use various artificial intelligence computing approaches like neural networks, Bayesian probability, fuzzy logic, machine learning, reinforcement learning, evolutionary computation and genetic algorithms. == Overview == Intelligent control can be divided into the following major sub-domains: Neural network control Machine learning control Reinforcement learning Bayesian control Fuzzy control Neuro-fuzzy control Expert Systems Genetic control New control techniques are created continuously as new models of intelligent behavior are created and computational methods developed to support them. === Neural network controller === Neural networks have been used to solve problems in almost all spheres of science and technology. Neural network control basically involves two steps: System identification Control It has been shown that a feedforward network with nonlinear, continuous and differentiable activation functions have universal approximation capability. Recurrent networks have also been used for system identification. Given, a set of input-output data pairs, system identification aims to form a mapping among these data pairs. Such a network is supposed to capture the dynamics of a system. For the control part, deep reinforcement learning has shown its ability to control complex systems. === Bayesian controllers === Bayesian probability has produced a number of algorithms that are in common use in many advanced control systems, serving as state space estimators of some variables that are used in the controller. The Kalman filter and the Particle filter are two examples of popular Bayesian control components. The Bayesian approach to controller design often requires an important effort in deriving the so-called system model and measurement model, which are the mathematical relationships linking the state variables to the sensor measurements available in the controlled system. In this respect, it is very closely linked to the system-theoretic approach to control design.
Digital signage
Digital signage is a segment of electronic signage that uses digital display technologies to present multimedia content in both public and private environments. Content may include video, images, text, or interactive media and is typically displayed for purposes such as advertising, information dissemination, branding, or entertainment. Digital signage systems can be either networked or standalone. Networked systems are managed through centralized content management systems (CMS), often cloud-based, enabling remote updates, scheduling, real-time data integration, and dynamic content delivery. These systems may also incorporate audience analytics, IoT sensors, or AI-driven personalization. Standalone systems, by contrast, operate without a network connection. They rely on local media playback via USB drives, SD cards, or internal storage. These solutions are simpler and suitable for locations where connectivity is limited or content changes infrequently. == Applications of digital signage == Digital signage is widely used in transportation hubs, retail stores, restaurants, corporate buildings, hotels, educational institutions, healthcare facilities, and public spaces. One prominent application of digital signage is Digital Out-of-Home (DOOH) advertising, which leverages digital signage displays in public spaces to deliver targeted advertisements to people outside of their homes. DOOH has become a significant segment of digital signage, providing advertisers with a dynamic and contextually relevant way to engage with audiences. == Components == === Hardware components === Digital signage hardware includes the physical equipment used to show multimedia content in public and private spaces. ==== Display devices ==== Display devices are the most prominent components of a digital signage system, serving as the primary medium for presenting content. Display devices come in various technologies, such as LCD, LED, and OLED formats, each offering different advantages in terms of clarity, color reproduction, and energy efficiency. In addition to flat-panel displays, projectors are also commonly used in digital signage, particularly in large-scale settings. Projectors can cast large-format visuals onto walls, screens, or other surfaces, providing flexibility in display size and positioning. Screen sizes vary widely to suit different applications. Smaller panels are often used in kiosks and point-of-sale systems, while larger displays, such as video walls and projection surfaces, are deployed in venues like stadiums, auditoriums, and other public spaces. Many digital signage displays are also equipped with touchscreen capabilities, allowing for interactive applications. These interactive displays are commonly used in information kiosks, wayfinding systems, and self-service applications. ==== Playback devices ==== Playback devices are specialized hardware components that manage the storage, processing, and transmission of multimedia content to digital signage displays and projectors. They serve as the crucial link between the content management system (CMS) and the visual output, ensuring seamless playback of static images, video files, animated graphics, and real-time content, such as news feeds. Playback devices can be standalone units or integrated into display hardware using System-on-Chip (SoC) technology. The latter reduces hardware complexity and installation time, making the system more efficient. These devices support remote or local content updates, allowing digital signage operators to manage networks effectively. Content can be updated via cloud-based platforms for centralized control or through direct interfaces on-site, depending on the system's configuration and deployment requirements. ==== Mounting systems ==== Mounting systems provide structural support for digital signage displays, enabling deployment across diverse environments. Typical configurations include wall mounts, ceiling mounts, and floor stands each engineered to meet specific spatial and functional requirements. === Software components === Digital signage software is responsible for content creation, scheduling, and management. It enables users to manage and distribute content to one or more playback devices. ==== Software compatibility ==== Digital signage software supports various operating systems, including Android, Windows, Linux, iOS, tvOS, webOS, Tizen, ChromeOS, macOS, and others. This allows customers to choose the hardware and software solution that best suits their digital signage needs. == Interactivity == Interactivity in digital signage allows users to interact directly with displays using input methods like touch, gestures, voice, or proximity sensors. This feature enables real-time responses and personalized content, improving the user experience. Interactive digital signage is commonly used in places like retail, transportation, education, and public spaces to create engaging and informative interactions. Additionally, self-service kiosks are often integrated into interactive signage solutions, allowing users to perform tasks such as ordering products, checking in for flights, accessing information, or making payments. These kiosks empower users to complete transactions or obtain services independently, improving efficiency and convenience in high-traffic locations. == Audience measurement and context-aware content adaptation == === Audience measurement === Cameras can be integrated into digital signage systems to enable audience measurement. They are used to detect and count viewers, estimate demographics such as age and gender, measure dwell time and attention, and sometimes analyze emotional reactions using computer vision techniques. This process is valuable for understanding audience behavior and refining business strategies. Privacy concerns are addressed by anonymizing collected data and avoiding the storage of personally identifiable information. === Context-aware digital signage === Context-aware digital signage refers to systems that adjust content based on environmental or audience data. The infrastructure supporting context awareness, including sensors and analytics systems, also facilitates the collection of audience insights. While these insights may be primarily used for reporting, optimization, or planning future campaigns rather than immediate content adjustments, they play a crucial role in the overall context-aware ecosystem. ==== Contextual information ==== Contextual information in the realm of context-aware digital signage refers to data about the environment, audience, and other factors that influence how digital signage content is displayed. This information helps the system to deliver more relevant, timely, and personalized content to its audience. Contextual information can include, but is not limited to: Audience demographics — this can involve detecting the age, gender, or even emotional state of viewers through cameras or sensors. It helps tailor content to specific audience segments, improving engagement. Time and weather — the system may adjust content based on the time of day or current weather conditions. For example, weather-appropriate content (like a raincoat ad on a rainy day) or time-specific content (like dinner menu promotions in the evening) can be shown. Emergency information — in situations of emergency, systems can prioritize displaying urgent notifications such as fire alerts, disaster warnings, or evacuation instructions. This can be crucial for public safety in crowded environments or densely populated areas. The system may adapt content in real-time to inform and guide individuals to safety, offering location-specific instructions or emergency service contacts. == Challenges == === Display blindness === Digital signage in public spaces has been found to lose visibility, significantly diminishing its ability to capture attention. This issue, known as "Display Blindness", was identified by Müller et al. and refers to the phenomenon where digital advertisements are largely overlooked by passersby. Observations indicate that many of these advertisements fail to resonate with their audience, often being irrelevant or unengaging, which leads to passive reception and reduced interaction. == Comparison with print signage == Digital signage and traditional print signage serve similar purposes by delivering visual information to a target audience, but they differ significantly in terms of flexibility, cost, maintenance, and environmental impact. Digital signage is advantageous in low-light or nighttime environments, where its internal illumination ensures visibility without the need for external lighting, unlike printed signs, which may require additional fixtures to be seen after dark. === Content and flexibility === Digital signage allows for dynamic and real-time content updates, often controlled remotely through content management systems. This makes it well-suited for environments where information chan
List of video games using NFC
This is a list of video games that use near field communication (NFC) technology. Currently, games have leveraged NFC in unlocking additional features through payment. This takes the form of a direct transaction over NFC or by purchasing a physical item, which signals to the platform that a certain set of features has been purchased (e.g. Skylanders). This list catalogues gaming NFC platforms by device. == Mobile == === Android === Gun Bros. Near Field Ninja NFC Cards Skylanders, with an NFC base. The Haunted House: Soul Fighters, with an NFC base. === iOS === ==== As item-triggered game enhancement ==== Skylanders, with an NFC base. ==== As payment ==== In-App Purchases Here, games that leverage Apple's In-App Purchase framework use information stored in the NFC Secure Element to process the purchase through Apple Pay. While an NFC radio is not used here, the NFC protocol is used nonetheless. == Console == === Nintendo Wii, Wii U, Switch, Switch 2, 3DS and 2DS === ==== As item-triggered game enhancement ==== Pokémon Rumble U NFC Figure Amiibo, built into Nintendo consoles since 2014. Works with Wii U, New Nintendo 3DS/3DS XL, New Nintendo 2DS XL, Nintendo Switch, Nintendo Switch 2 and older Nintendo 3DS/Nintendo 2DS systems via a peripheral device. Disney Infinity, with an NFC base. Works with Wii, Nintendo 3DS, Nintendo 2DS and Wii U. Lego Dimensions, with an NFC base. Works with Wii U. Skylanders, with an NFC base. Works with Wii, Nintendo 3DS, Nintendo 2DS and Wii U. The Nintendo Switch version of Skylanders: Imaginators uses the NFC built into the game controller, it is also has full backward compatibility with Nintendo Switch 2. Some functionalities are missing compared to the other versions. ==== As payment ==== The Wii U GamePad controller, Joy-Con R, Joy-Con 2 R, Nintendo Switch Pro Controller and Nintendo Switch 2 Pro Controller can read information from an NFC data source. === PlayStation === Disney Infinity, with an NFC base. Works with PlayStation 3, PlayStation Vita, PlayStation 4 and PlayStation 5. Lego Dimensions, with an NFC base. Works with PlayStation 3, PlayStation 4 and PlayStation 5. Skylanders, with an NFC base. Works with PlayStation 3, PlayStation 4 and PlayStation 5. === Xbox === While NFC bases are normally interoperable between all platforms, the Xbox 360, Xbox One and Xbox Series X require specific bases that are compatible only with the respective platform. Disney Infinity, with an NFC base. Lego Dimensions, with an NFC base. Skylanders, with an NFC base.
Brand networking
Brand networking is the engagement of a social networking service around a brand by providing consumers with a platform of relevant content, elements of participation, and a currency, score, or ranking. Brand networking creates communities that serve as interactive destinations to encourage brand participation online and off. This evolved level of user participation with the brand facilitates strong relationships with consumers, leverages sales, and generates fan equity. The concept builds on the marketing literature on brand communities, which describes specialized, non-geographically bound groups of consumers organized around shared interest in a brand, and on subsequent research on social-media-based brand communities that examines how such groups operate when embedded in general-purpose networking platforms. == History == The development and growth of social networking in the early 2000s gave birth to brand networking. Brands saw the immediate potential to reach and interact with consumers through online platforms like Facebook and MySpace. At first, the ability to reach consumers through these platforms was inadequate; brands had the option to join as members or simply advertise on these sites. The potential existed to not only display advertisements to consumers, but to encourage them to interact with the brand. This is when brands made the shift to create their own networking platforms. Less evolved attempts to connect brands with consumers via networking are typically built as online platforms meant only to complement a product/service and are limited in functionality. Typically these sites offer consumers the opportunity to interact through discussion boards and group pages. The Guiding Light Community was built to complement the popular CBS television soap opera. The site offers members reward points for contributing content to discussion boards and blogs (which is all geared toward the show). == Structure == Brand networking is more than the utilization of a social networking platform; it is connecting consumers together and constructing relationships directly with the brand. Three key elements, in unity, create effective brand networking: relevant content, elements of participation, and a competitive currency. Websites in conjunction with other media types (television, radio, print) present content around a vertical industry, sector of interest, or cultural and social issues for a brand. This can be in areas such as health, marketing, or business, or any content relevant to the brand message. Such content is not only provided by the brand but also in the form of consumer-generated media. Research on brand-related user-generated content across major platforms suggests that the form and tone of consumer contributions vary by platform, with promotional content more common on some networks and response-oriented content on others. A brand provides participation with consumers online and offline. This is accomplished through the combination of typical social networking features online, such as personalised pages, friend lists, groups, and messaging, alongside elements of involvement offline. This is not simply connecting an online platform with mobile devices, but providing separate mobile features jointly with a secondary media type to drive online usage and build relationships with the brand on the go. By participating in mobile campaigns, users are interacting with the brand outside of traditional brick and mortar or e-commerce destinations. Empirical work on consumer brand engagement in social media frames such participation along cognitive, affective, and behavioural dimensions. The final element of brand networking involves incentivising participation with the other two elements. The addition of a currency or point system acts as an anchor to the brand and network and creates a competitive dynamic between consumers. These points are distributed for activity carried out outside of the networking site. By incentivising usage offline, the brand image is reinforced for the consumer and strengthens the relationship. Consumers are turned into promoters for both the brand and the users' benefit. The use of points, badges, leaderboards, and similar mechanics is described in the marketing literature as gamification, and has been linked to higher participation rates in mobile and loyalty programmes. == Fan equity == Fan equity is the idea that by locking in consumers to a brand, they are turned into fans of the brand. As fans, they promote, interact, and consume on a daily basis and become assets. Apple Inc. is one example of a company often cited as possessing fan equity. Customers of Apple are extremely brand loyal and are assets to the company. Creating a fan-generated brand is a difficult but effective method of business. Through the use of brand networking, a company is able to build a consumer or fan base that provides a strong relationship between business and consumers. The trust is formed and fans do a lot of work for the brand by word of mouth. Peer-to-peer channels are the strongest means of communication for a brand, but also one in which the brand can only influence and not control. Subsequent research links community engagement with brand trust, identifying community engagement as a mediator between social-media brand community participation and trust. This method of business is argued to be a relationship handled by the brand generally for its own gain. Many fans do not realise the work they are doing for companies by using their product or service. Facebook is a fan-based brand that has become a global phenomenon through customer use, with social media features such as sharing and commenting. With the growth of social media, marketing and advertising through social media has continued to expand. Brands can display and promote their products or services at a fast rate, with consumers sharing and contributing to the brand on a global scale. This can also be seen as online word of mouth exposure that can produce positive or negative feedback for brands. Once consumers become fans they are typically loyal, which can create positive word of mouth for a brand. Fans become a valuable asset, boosting the status and reputation of a brand. Different perceptions of brands can be linked to a person's origin or religion, which creates a difficulty when trying to enter a market or gain market share. Businesses need to be aware of the types of products or services they introduce to a specific market, ensuring they are culturally sensitive. Fan pages are created on social media to maintain the relationship between brands and consumers. By engaging and interacting with consumers, brands obtain fans and produce positive imaging. Some fans become attached to brands and are often encouraged to remain as fans through the use of celebrities endorsing the brand. Research on parasocial interaction in social-media environments suggests that one-sided emotional bonds that consumers form with endorsers and brand personae help convert ordinary followers into engaged fans.
LemonStand
LemonStand was a Canadian e-commerce company headquartered in Vancouver, British Columbia, that developed cloud-based computer software for online retailers. LemonStand was shut down on June 5, 2019. == History == LemonStand Version 1 was launched on July 28, 2001. It is written in the PHP programming language. Version 1 was released as an on-premises proprietary licensed software, and the commercial license was not free. However, there was a free trial license available. June 2012, LemonStand raised seed funding from the BDC Venture Capital, and a group of angel investors. December 20, 2013, a cloud-based SaaS version of the LemonStand eCommerce platform was released publicly. May 9, 2014, LemonStand and Payfirma, a payments processing company, partnered to provide integrated services for online retailers. May 3, 2016, LemonStand raised funding from BDC Venture Capital and Silicon Valley–based angel investors. March 5, 2019, LemonStand announced their intention to shut down on June 5, 2019. LemonStand was quietly acquired by Mailchimp at the end of February. == Pricing == LemonStand offered three levels of service plans. LemonStand did not charge any transaction fees.
Hardware trojan
A hardware trojan (HT) is a malicious modification of the circuitry of an integrated circuit. A hardware trojan is completely characterized by its physical representation and its behavior. The payload of an HT is the entire activity that the Trojan executes when it is triggered. In general, trojans try to bypass or disable the security fence of a system: for example, leaking confidential information by radio emission. HTs also could disable, damage or destroy the entire chip or components of it. Hardware trojans may be introduced as hidden front-doors that are inserted while designing a computer chip, by using a pre-made application-specific integrated circuit (ASIC) semiconductor intellectual property core (IP core) that have been purchased from a non-reputable source, or inserted internally by a rogue employee, either acting on their own, or on behalf of rogue special interest groups, or state sponsored spying and espionage. One paper published by IEEE in 2015 explains how a hardware design containing a trojan could leak a cryptographic key leaked over an antenna or network connection, provided that the correct "easter egg" trigger is applied to activate the data leak. In high security governmental IT departments, hardware trojans are a well known problem when buying hardware such as: a KVM switch, keyboards, mice, network cards, or other network equipment. This is especially the case when purchasing such equipment from non-reputable sources that could have placed hardware trojans to leak keyboard passwords, or provide remote unauthorized entry. == Background == In a diverse global economy, outsourcing of production tasks is a common way to lower a product's cost. Embedded hardware devices are not always produced by the firms that design and/or sell them, nor in the same country where they will be used. Outsourced manufacturing can raise doubt about the evidence for the integrity of the manufactured product (i.e., one's certainty that the end-product has no design modifications compared to its original design). Anyone with access to the manufacturing process could, in theory, introduce some change to the final product. For complex products, small changes with large effects can be difficult to detect. The threat of a serious, malicious, design alteration can be especially relevant to government agencies. Resolving doubt about hardware integrity is one way to reduce technology vulnerabilities in the military, finance, energy and political sectors of an economy. Since fabrication of integrated circuits in untrustworthy factories is common, advanced detection techniques have emerged to discover when an adversary has hidden additional components in, or otherwise sabotaged, the circuit's function. == Characterization of hardware trojans == An HT can be characterized by several methods such as by its physical representation, activation phase and its action phase. Alternative methods characterize the HT by trigger, payload and stealth. === Physical characteristics === One of this physical trojan characteristics is the type. The type of a trojan can be either functional or parametric. A trojan is functional if the adversary adds or deletes any transistors or gates to the original chip design. The other kind of trojan, the parametric trojan, modifies the original circuitry, e.g. thinning of wires, weakening of flip-flops or transistors, subjecting the chip to radiation, or using focused ion-beams (FIB) to reduce the reliability of a chip. The size of a trojan is its physical extension or the number of components it is made of. Because a trojan can consist of many components, the designer can distribute the parts of a malicious logic on the chip. The additional logic can occupy the chip wherever it is needed to modify, add, or remove a function. Malicious components can be scattered, called loose distribution, or consist of only few components, called tight distribution, so the area is small where the malicious logic occupies the layout of the chip. In some cases, high-effort adversaries in may regenerate the layout so that the placement of the components of the IC is altered. In rare cases the chip dimension is altered. These changes are structural alterations. === Activation characteristics === The typical trojan is condition-based: It is triggered by sensors, internal logic states, a particular input pattern or an internal counter value. Condition-based trojans are detectable with power traces to some degree when inactive. That is due to the leakage currents generated by the trigger or counter circuit activating the trojan. Hardware trojans can be triggered in different ways. A trojan can be internally activated, which means it monitors one or more signals inside the IC. The malicious circuitry could wait for a count down logic an attacker added to the chip, so that the trojan awakes after a specific time-span. The opposite is externally activated. There can be malicious logic inside a chip, that uses an antenna or other sensors the adversary can reach from outside the chip. For example, a trojan could be inside the control system of a cruising missile. The owner of the missile does not know, that the enemy will be able to switch off the rockets by radio. A trojan which is always-on can be a reduced wire. A chip that is modified in this way produces errors or fails every time the wire is used intensely. Always-on circuits are hard to detect with power trace. In this context combinational trojans and sequential trojans are distinguished. A combinational trojan monitors internal signals until a specific condition happens. A sequential trojan is also an internally activated condition-based circuit, but it monitors the internal signals and searches for sequences not for a specific state or condition like the combinational trojans do. ==== Cryptographic key extraction ==== Extraction of secret keys by means of a hardware trojan without detecting the trojan requires that the trojan uses a random signal or some cryptographic implementation itself. To avoid storing a cryptographic key in the trojan itself and reduction, a physical unclonable function can be used. Physical unclonable functions are small in size and can have an identical layout while the cryptographic properties are different. === Action characteristics === A HT could modify the chip's function or could change the chip's parametric properties (e.g. provokes a process delay). Confidential information can also be transmitted to the adversary (transmission of key information). === Peripheral device hardware trojans === A relatively new threat vector to networks and network endpoints is a HT appearing as a physical peripheral device that is designed to interact with the network endpoint using the approved peripheral device's communication protocol. For example, a USB keyboard that hides all malicious processing cycles from the target network endpoint to which it is attached by communicating with the target network endpoint using unintended USB channels. Once sensitive data is ex-filtrated from the target network endpoint to the HT, the HT can process the data and decide what to do with the data: store the data to memory for later physical retrieval of the HT or possibly ex-filtrate the data to the internet using wireless or using the compromised network endpoint as a pivot. == Potential of threat == A common trojan is passive most of the time-span an altered device is in use. If a trojan is activated the device functionality can be changed, the device can be destroyed or disabled, the device can leak confidential information or the HT may tear down the security and safety of the device. Trojans are stealthy, to avoid detection of the trojan the precondition for activation is a very rare event. Traditional testing techniques are not sufficient. A manufacturing fault happens at a random position while malicious changes are well placed to avoid detection. == Detection == === Physical inspection === First, the molding coat is cut to reveal the circuitry. Then, the engineer repeatedly scans the surface while grinding the layers of the chip. There are several operations to scan the circuitry. Typical visual inspection methods are: scanning optical microscopy (SOM), scanning electron microscopy (SEM), pico-second imaging circuit analysis (PICA), voltage contrast imaging (VCI), light induced voltage alteration (LIVA) or charge induced voltage alteration (CIVA). To compare the floor plan of the chip has to be compared with the image of the actual chip. This is still quite challenging to do. To detect Trojan hardware which include (crypto) keys which are different, an image diff can be taken to reveal the different structure on the chip. The only known hardware Trojan using unique crypto keys but having the same structure is. This property enhances the undetectability of the trojan. === Functional testing === This detection method stimulates the input ports of a chip and monitors the output