Cancer Likelihood in Plasma

Cancer Likelihood in Plasma

Cancer Likelihood in Plasma (CLiP) refers to a set of ensemble learning methods for integrating various genomic features useful for the noninvasive detection of early cancers from blood plasma. An application of this technique for early detection of lung cancer (Lung-CLiP) was originally described by Chabon et al. (2020) from the labs of Ash Alizadeh and Max Diehn at Stanford. This method relies on several improvements to cancer personalized profiling by deep sequencing (CAPP-Seq) for analysis of circulating tumor DNA (ctDNA). The CLiP technique integrates multiple distinctive genomic features of a cancer of interest findings within a machine-learning framework for cancer detection. For example, studies have shown that the majority of somatic mutations found in cell-free DNA (cfDNA) are not tumor derived, but instead reflect clonal hematopoeisis (also known as CHIP). Even though CHIP tends to target specific genes, it also involves many generally non-recurrent mutations that can be shed from leukocytes and detected in cfDNA, regardless of whether profiling patients with cancer and healthy adults. However, genuine tumor derived ctDNA mutations can be distinguished from CHIP-derived mutations. This is because unlike tumor-derived mutations, CHIP-derived mutations that are shed from leukocytes into plasma tend to occur on longer cfDNA fragments, and to lack specific mutational signatures such as those associated with tobacco smoking in lung cancer that are also found in tumor derived ctDNA molecules. CLiP integrates these features within hierarchical ensemble machine learning models that consider somatic mutations and copy number alternations, among other features. While the CLiP method is unique in relying exclusively on mutations and copy number alterations, it is related to a variety of other liquid biopsy methods being commercially developed for early cancer detection using ctDNA and proteins (e.g., CancerSEEK / DETECT-A ), cfDNA fragmentation patterns (e.g., DELFI), and DNA methylation (e.g., cfMeDIP-Seq, Grail). While the CLiP method has not yet been broadly applied for population-based cancer screening, it has been shown to distinguish discriminate early-stage lung cancers from risk-matched controls across multiple cohorts of patients enrolled across the US.

Aphelion (software)

The Aphelion Imaging Software Suite is a software suite that includes three base products - Aphelion Lab, Aphelion Dev, and Aphelion SDK for addressing image processing and image analysis applications. The suite also includes a set of extension programs to implement specific vertical applications that benefit from imaging techniques. The Aphelion software products can be used to prototype and deploy applications, or can be integrated, in whole or in part, into a user's system as processing and visualization libraries whose components are available as both DLLs or .Net components. == History and evolution == The development of Aphelion started in 1995 as a joint project of a French company, ADCIS S.A., and an American company, Amerinex Applied Imaging, Inc. (AAI) Aphelion's image processing and analysis functions were made from operators available from the KBVision software developed and sold by Amerinex's predecessor, Amerinex Artificial Intelligence Inc. In the 1990s, the XLim software library was developed at the Center of Mathematical Morphology of Mines ParisTech, and both companies carried out its development tasks. The first version of Aphelion was completed and released in April 1996. Successive versions were released before the first official stable release in December 1996 at the Photonics East conference in Boston and the Solutions Vision show in Paris in January 1997, where at the latter it competed with Stemmer Imaging's CVB imaging toolbox. In 1998, version 2.3 of Aphelion for Windows 98 was released, and its user base was growing in both France and the United States. Version 3.0, totally rewritten to take advantage of Microsoft's then-recent ActiveX technology, was officially released in 2000. It also became available as a « Developer » version, for rapid prototyping of applications using its intuitive GUI and the macro recording capability, and a « Core » version, including the full library as a set of ActiveX components to be used by software developers, integrators and original equipment manufacturers (OEM). As AAI turned its focus to security, in 2001, ADCIS took the lead on developing Aphelion. AAI focused on millimeter wave scanners for concealed weapon detection at airports, and eventually merged with Millimetrics to become Millivision. In 2004, ADCIS specified version 4.0 of Aphelion. The set of image processing/analysis functions was rewritten one more time to be compatible with the .NET technology and the emergence of 64 bit architecture PCs. In addition, the GUI was redesigned to address two usage types: a semi-automatic use where the user is guided through the different steps of functions, and a fully automatic use where the expert user can quickly invoke imaging functions. Its first release was presented at the IPOT exhibition in Birmingham, UK the same year. During the Vision Show in Paris in October 2008, the new Aphelion Lab product was launched for users that are not specialists in image processing. It is easier to use, and only includes fewer image processing functions. It was then included in the Aphelion Image Processing Suite, consisting of Aphelion Dev (replacing Aphelion Developer), Aphelion Lab, Aphelion SDK (replacing Aphelion Core), and a set of extensions. Nowadays, ADCIS is still working on the suite, and updated versions with new extensions and functionalities continually become available from the websites of both companies. In 2015, support was added for very large images and scan microscope images (virtual slides compound into a very large JPEG 2000 image) for high throughput imaging, and new specific extensions were also added. In late 2015, ADCIS announced Aphelion's port for tablets and smartphones, for vertical applications. The name "Aphelion" comes from the astronomical term of the same name, meaning the point on a planet rotating around the Sun where it lies farthest from it, applying the term in a metaphorical sense. Unix was the operating system used on scientific workstations in the 1990s, such as on the workstations manufactured by market leader Sun Microsystems, which Windows suite Aphelion was quite removed from. == Description == Aphelion is a software suite to be used for image processing and image analysis. It supports 2D and 3D, monochrome, color, and multi-band images. It is developed by ADCIS, a French software house located in Saint-Contest, Calvados, Normandy. Aphelion is widely used in the scientific/industry community to solve basic and complex imaging applications. First, the imaging application is quickly developed from the Graphical User Interface, involving a set of functions that can be automatically recorded into a macro command. The macro languages available in Aphelion (i.e. BasicScript, Python, and C#) help to process batch of images, and prompt the user if needed for specific parameters that are applied to the imaging functions. All Aphelion image processing functions are written in C++, and the Aphelion user interface is written in C#. C++ functions can be called from the C# language thanks the use of dedicated wrappers. The main principle of image processing is to automatically process pixels of a digital image, then extract one or more objects of interest (i.e. cells in the field of biology, inclusions in the field of material science) and compute one or more measurements on those objects to quantify the image and generate a verdict (good image, image with defects, cancerous cells). In other words, starting from an image, pixels are processed by a set of successive functions or operators until only measurements are computed and used as the input of a 3rd party system or a classification software that will classify objects of interest that have been extracted during the imaging process. An acquisition system such as a digital camera, a video camera, an optical or electron microscope, a medical scanner, or a smartphone can be used to capture images. The set of values or pixels can be processed as a 1D image (1D signal), a 2D image (array of pixel values corresponding to a monochrome or color image), or a 3D image displayed using volume rendering (array of voxels in the 3D space) or displaying surfaces by using 3D rendering. A 2D color image is made of 3 value pixels (typically Red, Green, and Blue information or another color space), and a 3D image is made of monochrome, color (indexed color are often used), multispectral, or hyperspectral data. When dealing with videos, an additional band is added corresponding to temporal information. The Aphelion Software Suite includes three base products, and a set of optional extensions for specific applications: Aphelion Lab: Entry-level package for non-experts in image processing. It helps to quickly segment an image in a semi-automatic or manual ways, and compute a set of measurements computed on objects of interest that have been extracted during the segmentation process. A set of wizards guides the user from image acquisition to report generation. Aphelion Dev: Full imaging environment including over 450 functions to develop and deploy an application that involves image processing and analysis. It also includes a set of macro-command languages to automate any application to be invoked from the user interface. It also helps to run the imaging algorithm on more than one image that are stored on disk, available on the network, or captured by an acquisition device. Aphelion libraries for image processing and visualization are provided in Aphelion Dev as DLLs and .Net components. Aphelion SDK: A set of libraries to develop a stand-alone application with a custom interface based on the Aphelion libraries. This software development kit including display, processing and analysis functions that can be used by software developers and OEMs. It is provided as DLLs and .Net components. The stand-alone application is typically developed in C# on one computer, and then deployed on multiple PCs and systems. A set of optional extensions can be added to the « Aphelion Dev » product, depending on the application. An evaluation version of Aphelion can be run on a PC for 30 days. A permanent version of Aphelion is available based on a perpetual license. Upgrades are available through a maintenance agreement based on a yearly fee. Technical support is provided by the engineers who are developing the product. The goal of image processing is usually to extract object(s) of interest in an image, and then to classify them based on some characteristics such as shape, density, position, etc. Using Aphelion, this goal is achieved by performing the following tasks: Load an image from disk or acquire an image using an acquisition device. Enhance the image removing noise or modifying its contrast. Segment the image extracting objects of interest to be measured and analyzed. Typically, for simple applications, a threshold is performed to generate a binary image. Then, morphological operators are applied to clean the image and only keep obj

Computing Machinery and Intelligence

"Computing Machinery and Intelligence" is a paper written by Alan Turing on the topic of artificial intelligence. The paper, published in 1950 in Mind, was the first to introduce his concept of what is now known as the Turing test to the general public. Turing's paper considers the question "Can machines think?" Turing says that since the words "think" and "machine" cannot clearly be defined, we should "replace the question by another, which is closely related to it and is expressed in relatively unambiguous words." To achieve this objective, Turing proposes a three-step approach. First, he identifies a simple and unambiguous concept to substitute for the term "think." Second, he delineates the specific "machines" under consideration. Third, armed with these tools, he poses a new question related to the first, which he believes he can answer in the affirmative. == Turing's test == Rather than trying to determine if a machine is thinking, Turing suggests we should ask if the machine can win a game, called the "Imitation Game". The original Imitation game, that Turing described, is a simple party game involving three players. Player A is a man, player B is a woman and player C (who plays the role of the interrogator) can be of either sex. In the Imitation Game, player C is unable to see either player A or player B (and knows them only as X and Y), and can communicate with them only through written notes or any other form that does not give away any details about their gender. By asking questions of player A and player B, player C tries to determine which of the two is the man and which is the woman. Player A's role is to trick the interrogator into making the wrong decision, while player B attempts to assist the interrogator in making the right one. Turing proposes a variation of this game that involves the computer: We now ask the question, "What will happen when a machine takes the part of A in this game?" Will the interrogator decide wrongly as often when the game is played like this as he does when the game is played between a man and a woman? These questions replace our original, "Can machines think?" So the modified game becomes one that involves three participants in isolated rooms: a computer (which is being tested), a human, and a (human) judge. The human judge can converse with both the human and the computer by typing into a terminal. Both the computer and the human try to convince the judge that they are the human. If the judge cannot consistently tell which is which, then the computer wins the game. Researchers in the United Kingdom had been exploring "machine intelligence" for up to ten years prior to the founding of the field of artificial intelligence (AI) research in 1956. It was a common topic among the members of the Ratio Club, an informal group of British cybernetics and electronics researchers that included Alan Turing. Turing, in particular, had been running the notion of machine intelligence since at least 1941 and one of the earliest-known mentions of "computer intelligence" was made by him in 1947. As Stevan Harnad notes, the question has become "Can machines do what we (as thinking entities) can do?" In other words, Turing is no longer asking whether a machine can "think"; he is asking whether a machine can act indistinguishably from the way a thinker acts. This question avoids the difficult philosophical problem of pre-defining the verb "to think" and focuses instead on the performance capacities that being able to think makes possible, and how a causal system can generate them. Since Turing introduced his test, it has been both highly influential and widely criticised, and has become an important concept in the philosophy of artificial intelligence. Some of its criticisms, such as John Searle's Chinese room, are themselves controversial. Some have taken Turing's question to have been "Can a computer, communicating over a teleprinter, fool a person into believing it is human?" but it seems clear that Turing was not talking about fooling people but about generating human cognitive capacity. == Digital machines == Turing also notes that we need to determine which "machines" we wish to consider. He points out that a human clone, while man-made, would not provide a very interesting example. Turing suggested that we should focus on the capabilities of digital machinery—machines which manipulate the binary digits of 1 and 0, rewriting them into memory using simple rules. He gave two reasons. First, there is no reason to speculate whether or not they can exist. They already did in 1950. Second, digital machinery is "universal". Turing's research into the foundations of computation had proved that a digital computer can, in theory, simulate the behaviour of any other digital machine, given enough memory and time. (This is the essential insight of the Church–Turing thesis and the universal Turing machine.) Therefore, if any digital machine can "act like it is thinking", then every sufficiently powerful digital machine can. Turing writes, "all digital computers are in a sense equivalent." This allows the original question to be made even more specific. Turing now restates the original question as "Let us fix our attention on one particular digital computer C. Is it true that by modifying this computer to have an adequate storage, suitably increasing its speed of action, and providing it with an appropriate programme, C can be made to play satisfactorily the part of A in the imitation game, the part of B being taken by a man?" Hence, Turing states that the focus is not on "whether all digital computers would do well in the game nor whether the computers that are presently available would do well, but whether there are imaginable computers which would do well". What is more important is to consider the advancements possible in the state of our machines today regardless of whether we have the available resource to create one or not. == Nine common objections == Having clarified the question, Turing turned to answering it: he considered the following nine common objections, which include all the major arguments against artificial intelligence raised in the years since his paper was first published. Religious Objection: This states that thinking is a function of man's immortal soul; therefore, a machine cannot think. "In attempting to construct such machines," wrote Turing, "we should not be irreverently usurping His power of creating souls, any more than we are in the procreation of children: rather we are, in either case, instruments of His will providing mansions for the souls that He creates." 'Heads in the Sand' Objection: "The consequences of machines thinking would be too dreadful. Let us hope and believe that they cannot do so." This thinking is popular among intellectual people, as they believe superiority derives from higher intelligence and the possibility of being overtaken is a threat (as machines have efficient memory capacities and processing speed, machines exceeding the learning and knowledge capabilities are highly probable). This objection is a fallacious appeal to consequences, confusing what should not be with what can or cannot be (Wardrip-Fruin, 56). The Mathematical Objection: This objection uses mathematical theorems, such as Gödel's incompleteness theorem, to show that there are limits to what questions a computer system based on logic can answer. Turing suggests that humans are too often wrong themselves and pleased at the fallibility of a machine. (This argument would be made again by philosopher John Lucas in 1961 and physicist Roger Penrose in 1989, and later would be called Penrose–Lucas argument.) Argument From Consciousness: This argument, suggested by Professor Geoffrey Jefferson in his 1949 Lister Oration (acceptance speech for his 1948 award of Lister Medal) states that "not until a machine can write a sonnet or compose a concerto because of thoughts and emotions felt, and not by the chance fall of symbols, could we agree that machine equals brain." Turing replies by saying that we have no way of knowing that any individual other than ourselves experiences emotions, and that therefore we should accept the test. He adds, "I do not wish to give the impression that I think there is no mystery about consciousness ... [b]ut I do not think these mysteries necessarily need to be solved before we can answer the question [of whether machines can think]." (This argument, that a computer can't have conscious experiences or understanding, would be made in 1980 by philosopher John Searle in his Chinese room argument. Turing's reply is now known as the "other minds reply". See also Can a machine have a mind? in the philosophy of AI.) Arguments from various disabilities. These arguments all have the form "a computer will never do X". Turing offers a selection:Be kind, resourceful, beautiful, friendly, have initiative, have a sense of humour, tell right from wrong, make mistakes, fall in love, enjo

ECML PKDD

ECML PKDD, the European Conference on Machine Learning Principles and Practice of Knowledge Discovery in Databases, is one of the leading academic conferences on machine learning and knowledge discovery, held in Europe every year. == History == ECML PKDD is a merger of two European conferences, European Conference on Machine Learning (ECML) and European Conference on Principles and Practice of Knowledge Discovery in Databases (PKDD). ECML and PKDD have been co-located since 2001; however, both ECML and PKDD retained their own identity until 2007. For example, the 2007 conference was known as "the 18th European Conference on Machine Learning (ECML) and the 11th European Conference on Principles and Practice of Knowledge Discovery in Databases (PKDD)", or in brief, "ECML/PKDD 2007", and both ECML and PKDD had their own conference proceedings. In 2008 the conferences were merged into one conference, and the division into traditional ECML topics and traditional PKDD topics was removed. The history of ECML dates back to 1986, when the European Working Session on Learning was first held. In 1993 the name of the conference was changed to European Conference on Machine Learning. PKDD was first organised in 1997. Originally PKDD stood for the European Symposium on Principles of Data Mining and Knowledge Discovery from Databases. The name European Conference on Principles and Practice of Knowledge Discovery in Databases was used since 1999. The conference remains highly competitive, consistently maintaining an average acceptance rate of around 25% for the main research track. == Upcoming conferences == == List of past conferences ==

Refik Anadol

Refik Anadol (born November 7, 1985) is a Turkish American media artist and the co-founder of Refik Anadol Studio and Dataland. Recognized as a pioneer in the aesthetics of data visualization and AI arts, his work merges art, technology, science, and architecture. Through media embedded into existing architecture, live audio-visual performances, immersive rooms, exhibitions, AI data paintings and sculptures, and digital collections, Anadol explores collective memories, humanity's relationship to nature, the perception of space and time, and human-machine collaborations. His work has been exhibited in more than seventy cities on six continents. == Early life and education == Anadol was born and raised in Istanbul and grew up in a family of teachers. He taught himself basic programming on a Commodore 64 when he was eight. His connection to machines began with coding and video games. Anadol saw Blade Runner for the first time when he was eight; his mother said the way he perceived his surroundings shifted the day after he saw the film. He was fascinated with its futuristic depiction of downtown Los Angeles, and transfixed by as a scene during which a replicant discovers that her memories are an implanted component of her machine mind, In a 2024 interview with the Financial Times, he said: "Since that moment, one of my inspirations has been that question: 'What can a machine do with someone else's memories?" Anadol attended Istanbul Bilgi University, where he received a BA in photography and video in 2009 and an MFA in visual communication in 2011. In 2014 he earned an MFA in design media arts at UCLA. He was mentored by Casey Reas, Jennifer Steinkamp, and Christian Moeller. == Career and selected works == === 2008–2012: Data painting, Quadrature and Quadrangle, Istanbul Biennial === As an undergraduate, Anadol read a paper by Lev Manovich on augmented space. Manovich's assertion that collaborations between architects and artists could make the "invisible flow of data visible" triggered Anadol's imagination, and in 2008, he altered built space for the first time. Bringing a projector outside, he projected large-scale images onto a concrete to create the illusion of movement. Coining the term "data painting," the piece inspired Anadol to use light as material and data as pigment. In 2010 he created Quadrature with Alican Aktürk, a fellow graduate student, at the SantralIstanbul Art and Culture Center's main gallery building. A live audio-visual performance that examined the relationship between architecture and media, Quadrature used video projection techniques to manipulate footage of quadrilaterals. He followed Quadrature with Quadrangle at SANAA School of Design in Essen, Germany, using the entire 360 degrees of the building as a canvas. In 2011, he was invited to create a media installation at the Istanbul Biennial on the heavily trafficked İstiklal Avenue. He created a site-specific large-scale interpretation of sounds he recorded during different times of day, and used nine projectors to project reinterpreted images. The work was titled Augmented Structures v1.0. Anadol's first solo exhibition, Sceptical Interventions, was held at the Piveneli Gallery in Istanbul in early 2012. Later that year he moved to Los Angeles to attend UCLA's Design Media Arts program. The first place he went after his arrival was downtown Los Angeles. [6] === 2013–2016: Visions of America: Amériques, Infinity Room, Google AMI === In 2013, at Microsoft Research's annual Design Expo, Anadol presented his idea to use the external walls of Walt Disney Concert Hall as a canvas. His presentation brought him to the attention of Gehry Technologies, and with the support of Gehry and his team, Anadol was offered the use of the original 3D model of the concert hall. For his 2014 thesis project, with assistance from architects and UCLA researchers, he created a site-specific architectural video installation inside the concert hall that accompanied a Los Angeles Philharmonic performance of Edgard Varèse's Amérique. Titled Visions of America: Amériques, Anadol used algorithmic sound analysis to listen and respond to the music in real-time. He tracked conductor Esa-Pekka Salonen's heartbeat with a sensor and used a 3-D camera system to integrate Salonen's movements. He created Infinity Room at the Zorlu PSM for the 2015 Istanbul Biennial. Rather than creating an illusion only with mirrors, Anadol used pixel and 3D projection mapping to transform every surface of the room into an abstract infinite moving space. A temporary immersive environment, Infinity Room was also exhibited at events including South by Southwest in Austin, Texas, the New Zealand Festival in Wellington, New Zealand, and Jeffrey Deitch in Los Angeles. In 2016, Anadol was awarded the first Google Artists and Machine Intelligence Artist Residency; it was just after a team at Google opened up the algorithm for DeepDream, a computer vision program that prompted Anadol's realization that if a machine could learn, it could remember, dream, and hallucinate. === 2017–2018: Winds of Boston, Archive Dreaming, Melting Memories, WDCH Dreams === In 2017, he created the data painting Winds of Boston, a 6' x 13' foot video installation in the lobby of a Boston office building, using software he created to read, analyze and visualize wind speed, direction, and gust patterns along with time and temperature at 20-second intervals recorded over a one-year period at Logan International Airport. Later in the year, he used AI to generate infinite new outputs based on a massive dataset for Archive Dreaming, an immersive installation at Salt Research, a contemporary gallery and library in Istanbul. Inspired by his idea of consciousness and its context within AI, as well as Jorge Luis Borges' The Library of Babel, Anadol used AI and machine learning to look at and discover interactions and correlations between 1.7 million items culled from 40,000 publications covering Turkish contemporary and modern art, architecture, and economics from 1997 to 2010. Archive Dreaming, which could be controlled by users with a joystick, dreamed of unexpected correlations among documents when idle. In 2018, after his uncle was diagnosed with Alzheimer's, Anadol created Melting Memories. Working with scientists from the neuroscape laboratory at the University of California, San Francisco, he used academic data from the neuroscience archives and EEG scans of an anonymous Alzheimer's disease dataset to create AI-generated visuals related to memory, health, degeneration, and decay.Melting Memories was projected on the walls of Pilevneli Gallery; visitors to the exhibition could watch as millions of pixels reconstructed people's memories. Anadol won the Lumen Prize Gold Award for Melting Memories. Anadol was commissioned by the Los Angeles Philharmonic to create an installation to celebrate the orchestra's centennial anniversary in 2018. He worked with Google's Kenric MacDowell to create WDCH Dreams, using algorithmic visualizations of data to mimic the process of human dreaming. Projected across the exterior walls of Walt Disney Concert Hall using 42 large-scale projectors with 50K visual resolution, 8-channel sound, and 1.2M luminance, Anadol painted with data points culled from the orchestra's archives, including 587,763 images, 1,880 videos, 1,483 metadata files, and 17,773 audio files. Because Gehry gave him access to the 3D architectural files of Walt Disney Concert Hall, Anadol knew the exact contours of the building. WDCH Dreams debuted in September 2018. A 12-minute performance in three parts staged every 30 minutes over ten nights, "Centennial Memories,” the first piece, used 44.5 terabytes of historical data from the Phil's archives. It was followed by "Consciousness", which processed every note the orchestra has ever recorded, using billions of data points to generate connections; and "Dream," which merged "Centennial Memories" and "Consciousness" to create hallucinations that were described in the New York Times as "a sort of combinatorial Fantasia. === 2019–2021: Machine Hallucinations: NYC, Machine Hallucinations: Nature Dreams, Machine Memories: Space, Quantum Memories === In 2019, Refik Anadol presented Latent History at Fotografiska Stockholm. The site specific installation transformed photographic archives of Stockholm into a large scale, machine generated visual projection displayed in the museum’s main exhibition hall. Drawing on thousands of archival images spanning approximately 150 years, the work used artificial intelligence to reinterpret the city’s historical imagery as a continuously evolving visual narrative.. Anadol began thinking about the work that would become the Machine Hallucinations series while in residence at Google. In 2019, he completed the first work in the series, Machine Hallucinations: NYC, which used 300 million photos of New York City and 113 million additional data points, including subway sounds, ra

Jive (software)

Jive (formerly known as Clearspace, then Jive SBS, then Jive Engage) is a commercial Java EE-based Enterprise 2.0 collaboration and knowledge management tool produced by Jive Software. It was first released as "Clearspace" in 2006, then renamed SBS (for "Social Business Software") in March 2009, then renamed "Jive Engage" in 2011, and renamed simply to "Jive" in 2012. Jive integrates the functionality of online communities, microblogging, social networking, discussion forums, blogs, wikis, and IM under one unified user interface. Content placed into any of the systems (blog, wiki, documentation, etc.) can be found through a common search interface. Other features include RSS capability, email integration, a reputation and reward system for participation, personal user profiles, JAX-WS web service interoperability, and integration with the Spring Framework. The product is a pure-Java server-side web application and will run on any platform where Java (JDK 1.5 or higher) is installed. It does not require a dedicated server - users have reported successful deployment in both shared environments and multiple machine clusters. As of Jive 8, released March 30, 2015, there is a Jive-n version which is for internal use (hosted by the consumer or hosted by Jive as a service) and a Jive-x version which is an external version hosted as a service. Jive no longer supports wiki markup language. == Server requirements for Jive 8-n == The following are the server requirements for Jive 8-n Operating systems: RHEL version 6 or 7 for x86_64, CentOS version 6 or 7 for x86_64 or SuSE Enterprise Linux Server (SLES) 11 and 12 for x86_64 Application Servers: Jive ships with its own embedded Apache HTTPD and Tomcat servers as part of the install package. It is not possible to deploy the application onto other appservers. Databases: MySQL (5.1, 5.5, 5.6) Oracle (11gR2, 12c) Postgres (9.0, 9.1, 9.2, 9.3, 9.4 - 9.2 or higher recommended) Microsoft SQL Server (2008R2, 2012, 2014) Environment: Jive recommends a server with at least 4GB of RAM and a dual-core 2 GHz processor with x86_64 architecture The product integrates with an LDAP repository or Active Directory For optimal deployment with a large community Jive Software recommends: using dedicated cache and document-conversion servers hosting the application and database servers separately == Releases == Jive 8, released on March 30, 2015 Jive 7, released in October 2013 Jive 9.0.x, released in November 2016 Jive 9, released in November 2016, supported now

Pippit

Pippit (Chinese: 小云雀; pinyin: Xiǎoyúnquè) is an artificial intelligence content creation platform developed by the Chinese technology company ByteDance. The platform, powered by CapCut leverages multimodal AI technology to streamline professional-grade video and image production, specifically targeting small and medium-sized enterprisesand social media creators. == History == In May 2025, ByteDance officially launched Pippit, which is positioned as an AI video and picture creation tool. In early 2026, Pippit underwent a major architectural overhaul with the integration of the Dreamina seedance 2.0. This technical milestone introduced the "Short Drama Agent" functionality, which enables the end-to-end conversion of scripts up to 100,000 words into fully rendered video productions.