In mathematics and computer algebra the factorization of a polynomial consists of decomposing it into a product of irreducible factors. This decomposition is theoretically possible and is unique for polynomials with coefficients in any field, but rather strong restrictions on the field of the coefficients are needed to allow the computation of the factorization by means of an algorithm. In practice, algorithms have been designed only for polynomials with coefficients in a finite field, in the field of rationals or in a finitely generated field extension of one of them. All factorization algorithms, including the case of multivariate polynomials over the rational numbers, reduce the problem to this case; see polynomial factorization. It is also used for various applications of finite fields, such as coding theory (cyclic redundancy codes and BCH codes), cryptography (public key cryptography by the means of elliptic curves), and computational number theory. As the reduction of the factorization of multivariate polynomials to that of univariate polynomials does not have any specificity in the case of coefficients in a finite field, only polynomials with one variable are considered in this article. == Background == === Finite field === The theory of finite fields, whose origins can be traced back to the works of Gauss and Galois, has played a part in various branches of mathematics. Due to the applicability of the concept in other topics of mathematics and sciences like computer science there has been a resurgence of interest in finite fields and this is partly due to important applications in coding theory and cryptography. Applications of finite fields introduce some of these developments in cryptography, computer algebra and coding theory. A finite field or Galois field is a field with a finite order (number of elements). The order of a finite field is always a prime or a power of prime. For each prime power q = pr, there exists exactly one finite field with q elements, up to isomorphism. This field is denoted GF(q) or Fq. If p is prime, GF(p) is the prime field of order p; it is the field of residue classes modulo p, and its p elements are denoted 0, 1, ..., p−1. Thus a = b in GF(p) means the same as a ≡ b (mod p). === Irreducible polynomials === Let F be a finite field. As for general fields, a non-constant polynomial f in F[x] is said to be irreducible over F if it is not the product of two polynomials of positive degree. A polynomial of positive degree that is not irreducible over F is called reducible over F. Irreducible polynomials allow us to construct the finite fields of non-prime order. In fact, for a prime power q, let Fq be the finite field with q elements, unique up to isomorphism. A polynomial f of degree n greater than one, which is irreducible over Fq, defines a field extension of degree n which is isomorphic to the field with qn elements: the elements of this extension are the polynomials of degree lower than n; addition, subtraction and multiplication by an element of Fq are those of the polynomials; the product of two elements is the remainder of the division by f of their product as polynomials; the inverse of an element may be computed by the extended GCD algorithm (see Arithmetic of algebraic extensions). It follows that, to compute in a finite field of non prime order, one needs to generate an irreducible polynomial. For this, the common method is to take a polynomial at random and test it for irreducibility. For sake of efficiency of the multiplication in the field, it is usual to search for polynomials of the shape xn + ax + b. Irreducible polynomials over finite fields are also useful for pseudorandom number generators using feedback shift registers and discrete logarithm over F2n. The number of irreducible monic polynomials of degree n over Fq is the number of aperiodic necklaces, given by Moreau's necklace-counting function Mq(n). The closely related necklace function Nq(n) counts monic polynomials of degree n which are primary (a power of an irreducible); or alternatively irreducible polynomials of all degrees d which divide n. === Example === The polynomial P = x4 + 1 is irreducible over Q but not over any finite field. On any field extension of F2, P = (x + 1)4. On every other finite field, at least one of −1, 2 and −2 is a square, because the product of two non-squares is a square and so we have If − 1 = a 2 , {\displaystyle -1=a^{2},} then P = ( x 2 + a ) ( x 2 − a ) . {\displaystyle P=(x^{2}+a)(x^{2}-a).} If 2 = b 2 , {\displaystyle 2=b^{2},} then P = ( x 2 + b x + 1 ) ( x 2 − b x + 1 ) . {\displaystyle P=(x^{2}+bx+1)(x^{2}-bx+1).} If − 2 = c 2 , {\displaystyle -2=c^{2},} then P = ( x 2 + c x − 1 ) ( x 2 − c x − 1 ) . {\displaystyle P=(x^{2}+cx-1)(x^{2}-cx-1).} === Complexity === Polynomial factoring algorithms use basic polynomial operations such as products, divisions, gcd, powers of one polynomial modulo another, etc. A multiplication of two polynomials of degree at most n can be done in O(n2) operations in Fq using "classical" arithmetic, or in O(nlog(n) log(log(n)) ) operations in Fq using "fast" arithmetic. A Euclidean division (division with remainder) can be performed within the same time bounds. The cost of a polynomial greatest common divisor between two polynomials of degree at most n can be taken as O(n2) operations in Fq using classical methods, or as O(nlog2(n) log(log(n)) ) operations in Fq using fast methods. For polynomials h, g of degree at most n, the exponentiation hq mod g can be done with O(log(q)) polynomial products, using exponentiation by squaring method, that is O(n2log(q)) operations in Fq using classical methods, or O(nlog(q)log(n) log(log(n))) operations in Fq using fast methods. In the algorithms that follow, the complexities are expressed in terms of number of arithmetic operations in Fq, using classical algorithms for the arithmetic of polynomials. == Factoring algorithms == Many algorithms for factoring polynomials over finite fields include the following three stages: Square-free factorization Distinct-degree factorization Equal-degree factorization An important exception is Berlekamp's algorithm, which combines stages 2 and 3. === Berlekamp's algorithm === Berlekamp's algorithm is historically important as being the first factorization algorithm which works well in practice. However, it contains a loop on the elements of the ground field, which implies that it is practicable only over small finite fields. For a fixed ground field, its time complexity is polynomial, but, for general ground fields, the complexity is exponential in the size of the ground field. === Square-free factorization === The algorithm determines a square-free factorization for polynomials whose coefficients come from the finite field Fq of order q = pm with p a prime. This algorithm firstly determines the derivative and then computes the gcd of the polynomial and its derivative. If it is not one then the gcd is again divided into the original polynomial, provided that the derivative is not zero (a case that exists for non-constant polynomials defined over finite fields). This algorithm uses the fact that, if the derivative of a polynomial is zero, then it is a polynomial in xp, which is, if the coefficients belong to Fp, the pth power of the polynomial obtained by substituting x by x1/p. If the coefficients do not belong to Fp, the pth root of a polynomial with zero derivative is obtained by the same substitution on x, completed by applying the inverse of the Frobenius automorphism to the coefficients. This algorithm works also over a field of characteristic zero, with the only difference that it never enters in the blocks of instructions where pth roots are computed. However, in this case, Yun's algorithm is much more efficient because it computes the greatest common divisors of polynomials of lower degrees. A consequence is that, when factoring a polynomial over the integers, the algorithm which follows is not used: one first computes the square-free factorization over the integers, and to factor the resulting polynomials, one chooses a p such that they remain square-free modulo p. Algorithm: SFF (Square-Free Factorization) Input: A monic polynomial f in Fq[x] where q = pm Output: Square-free factorization of f R ← 1 # Make w be the product (without multiplicity) of all factors of f that have # multiplicity not divisible by p c ← gcd(f, f′) w ← f/c # Step 1: Identify all factors in w i ← 1 while w ≠ 1 do y ← gcd(w, c) fac ← w / y R ← R · faci w ← y; c ← c / y; i ← i + 1 end while # c is now the product (with multiplicity) of the remaining factors of f # Step 2: Identify all remaining factors using recursion # Note that these are the factors of f that have multiplicity divisible by p if c ≠ 1 then c ← c1/p R ← R·SFF(c)p end if Output(R) The idea is to identify the product of all irreducible factors of f with the same multiplicity. This is done in two steps. The first step uses the formal d
EM algorithm and GMM model
In statistics, EM (expectation maximization) algorithm handles latent variables, while GMM is the Gaussian mixture model. == Background == In the picture below, are shown the red blood cell hemoglobin concentration and the red blood cell volume data of two groups of people, the Anemia group and the control group (i.e. the group of people without Anemia). As expected, people with Anemia have lower red blood cell volume and lower red blood cell hemoglobin concentration than those without Anemia. x {\displaystyle x} is a random vector such as x := ( red blood cell volume , red blood cell hemoglobin concentration ) {\displaystyle x:={\big (}{\text{red blood cell volume}},{\text{red blood cell hemoglobin concentration}}{\big )}} , and from medical studies it is known that x {\displaystyle x} are normally distributed in each group, i.e. x ∼ N ( μ , Σ ) {\displaystyle x\sim {\mathcal {N}}(\mu ,\Sigma )} . z {\displaystyle z} is denoted as the group where x {\displaystyle x} belongs, with z i = 0 {\displaystyle z_{i}=0} when x i {\displaystyle x_{i}} belongs to the Anemia group and z i = 1 {\displaystyle z_{i}=1} when x i {\displaystyle x_{i}} belongs to the control group. Also z ∼ Categorical ( k , ϕ ) {\displaystyle z\sim \operatorname {Categorical} (k,\phi )} where k = 2 {\displaystyle k=2} , ϕ j ≥ 0 , {\displaystyle \phi _{j}\geq 0,} and ∑ j = 1 k ϕ j = 1 {\displaystyle \sum _{j=1}^{k}\phi _{j}=1} . See Categorical distribution. The following procedure can be used to estimate ϕ , μ , Σ {\displaystyle \phi ,\mu ,\Sigma } . A maximum likelihood estimation can be applied: ℓ ( ϕ , μ , Σ ) = ∑ i = 1 m log ( p ( x ( i ) ; ϕ , μ , Σ ) ) = ∑ i = 1 m log ∑ z ( i ) = 1 k p ( x ( i ) ∣ z ( i ) ; μ , Σ ) p ( z ( i ) ; ϕ ) {\displaystyle \ell (\phi ,\mu ,\Sigma )=\sum _{i=1}^{m}\log(p(x^{(i)};\phi ,\mu ,\Sigma ))=\sum _{i=1}^{m}\log \sum _{z^{(i)}=1}^{k}p\left(x^{(i)}\mid z^{(i)};\mu ,\Sigma \right)p(z^{(i)};\phi )} As the z i {\displaystyle z_{i}} for each x i {\displaystyle x_{i}} are known, the log likelihood function can be simplified as below: ℓ ( ϕ , μ , Σ ) = ∑ i = 1 m log p ( x ( i ) ∣ z ( i ) ; μ , Σ ) + log p ( z ( i ) ; ϕ ) {\displaystyle \ell (\phi ,\mu ,\Sigma )=\sum _{i=1}^{m}\log p\left(x^{(i)}\mid z^{(i)};\mu ,\Sigma \right)+\log p\left(z^{(i)};\phi \right)} Now the likelihood function can be maximized by making partial derivative over μ , Σ , ϕ {\displaystyle \mu ,\Sigma ,\phi } , obtaining: ϕ j = 1 m ∑ i = 1 m 1 { z ( i ) = j } {\displaystyle \phi _{j}={\frac {1}{m}}\sum _{i=1}^{m}1\{z^{(i)}=j\}} μ j = ∑ i = 1 m 1 { z ( i ) = j } x ( i ) ∑ i = 1 m 1 { z ( i ) = j } {\displaystyle \mu _{j}={\frac {\sum _{i=1}^{m}1\{z^{(i)}=j\}x^{(i)}}{\sum _{i=1}^{m}1\left\{z^{(i)}=j\right\}}}} Σ j = ∑ i = 1 m 1 { z ( i ) = j } ( x ( i ) − μ j ) ( x ( i ) − μ j ) T ∑ i = 1 m 1 { z ( i ) = j } {\displaystyle \Sigma _{j}={\frac {\sum _{i=1}^{m}1\{z^{(i)}=j\}(x^{(i)}-\mu _{j})(x^{(i)}-\mu _{j})^{T}}{\sum _{i=1}^{m}1\{z^{(i)}=j\}}}} If z i {\displaystyle z_{i}} is known, the estimation of the parameters results to be quite simple with maximum likelihood estimation. But if z i {\displaystyle z_{i}} is unknown it is much more complicated. Being z {\displaystyle z} a latent variable (i.e. not observed), with unlabeled scenario, the expectation maximization algorithm is needed to estimate z {\displaystyle z} as well as other parameters. Generally, this problem is set as a GMM since the data in each group is normally distributed. In machine learning, the latent variable z {\displaystyle z} is considered as a latent pattern lying under the data, which the observer is not able to see very directly. x i {\displaystyle x_{i}} is the known data, while ϕ , μ , Σ {\displaystyle \phi ,\mu ,\Sigma } are the parameter of the model. With the EM algorithm, some underlying pattern z {\displaystyle z} in the data x i {\displaystyle x_{i}} can be found, along with the estimation of the parameters. The wide application of this circumstance in machine learning is what makes EM algorithm so important. == EM algorithm in GMM == The EM algorithm consists of two steps: the E-step and the M-step. Firstly, the model parameters and the z ( i ) {\displaystyle z^{(i)}} can be randomly initialized. In the E-step, the algorithm tries to guess the value of z ( i ) {\displaystyle z^{(i)}} based on the parameters, while in the M-step, the algorithm updates the value of the model parameters based on the guess of z ( i ) {\displaystyle z^{(i)}} of the E-step. These two steps are repeated until convergence is reached. The algorithm in GMM is: Repeat until convergence: 1. (E-step) For each i , j {\displaystyle i,j} , set w j ( i ) := p ( z ( i ) = j | x ( i ) ; ϕ , μ , Σ ) {\displaystyle w_{j}^{(i)}:=p\left(z^{(i)}=j|x^{(i)};\phi ,\mu ,\Sigma \right)} 2. (M-step) Update the parameters ϕ j := 1 m ∑ i = 1 m w j ( i ) {\displaystyle \phi _{j}:={\frac {1}{m}}\sum _{i=1}^{m}w_{j}^{(i)}} μ j := ∑ i = 1 m w j ( i ) x ( i ) ∑ i = 1 m w j ( i ) {\displaystyle \mu _{j}:={\frac {\sum _{i=1}^{m}w_{j}^{(i)}x^{(i)}}{\sum _{i=1}^{m}w_{j}^{(i)}}}} Σ j := ∑ i = 1 m w j ( i ) ( x ( i ) − μ j ) ( x ( i ) − μ j ) T ∑ i = 1 m w j ( i ) {\displaystyle \Sigma _{j}:={\frac {\sum _{i=1}^{m}w_{j}^{(i)}\left(x^{(i)}-\mu _{j}\right)\left(x^{(i)}-\mu _{j}\right)^{T}}{\sum _{i=1}^{m}w_{j}^{(i)}}}} With Bayes' rule, the following result is obtained by the E-step: p ( z ( i ) = j | x ( i ) ; ϕ , μ , Σ ) = p ( x ( i ) | z ( i ) = j ; μ , Σ ) p ( z ( i ) = j ; ϕ ) ∑ l = 1 k p ( x ( i ) | z ( i ) = l ; μ , Σ ) p ( z ( i ) = l ; ϕ ) {\displaystyle p\left(z^{(i)}=j|x^{(i)};\phi ,\mu ,\Sigma \right)={\frac {p\left(x^{(i)}|z^{(i)}=j;\mu ,\Sigma \right)p\left(z^{(i)}=j;\phi \right)}{\sum _{l=1}^{k}p\left(x^{(i)}|z^{(i)}=l;\mu ,\Sigma \right)p\left(z^{(i)}=l;\phi \right)}}} According to GMM setting, these following formulas are obtained: p ( x ( i ) | z ( i ) = j ; μ , Σ ) = 1 ( 2 π ) n / 2 | Σ j | 1 / 2 exp ( − 1 2 ( x ( i ) − μ j ) T Σ j − 1 ( x ( i ) − μ j ) ) {\displaystyle p\left(x^{(i)}|z^{(i)}=j;\mu ,\Sigma \right)={\frac {1}{(2\pi )^{n/2}\left|\Sigma _{j}\right|^{1/2}}}\exp \left(-{\frac {1}{2}}\left(x^{(i)}-\mu _{j}\right)^{T}\Sigma _{j}^{-1}\left(x^{(i)}-\mu _{j}\right)\right)} p ( z ( i ) = j ; ϕ ) = ϕ j {\displaystyle p\left(z^{(i)}=j;\phi \right)=\phi _{j}} In this way, a switch between the E-step and the M-step is possible, according to the randomly initialized parameters.
Aidoc
Aidoc Medical is an Israeli technology company that develops computer-aided simple triage and notification systems. Aidoc has obtained U.S. Food and Drug Administration and CE mark approval for its stroke, pulmonary embolism, cervical fracture, intracranial hemorrhage, intra-abdominal free gas, and incidental pulmonary embolism algorithms. Aidoc algorithms are in use in more than 900 hospitals and imaging centers, including Montefiore Nyack Hospital, LifeBridge Health, LucidHealth, Yale New Haven Hospital, Cedars-Sinai Medical Center, University of Rochester Medical Center, and Sheba Medical Center. == History == Aidoc was founded in 2016 by Elad Walach as the CEO, Michael Braginsky as the CTO and Guy Reiner as the VP. In April 2017, the company raised $7M, led by TLV Partners, and in April 2019, the company raised another $27M, led by Square Peg capital. There have been several additional rounds of funding as well, bringing Aidoc's total investment to $370M as of July 2025. In August 2018, Aidoc gained FDA clearance for its intracranial hemorrhage system, and in May 2019 it received clearance for the pulmonary embolism system. In January 2020, the system for detecting large-vessel occlusions (LVOs) in head CTA examinations obtained FDA clearance. In October 2024, it was reported that Aidoc is working with NVIDIA to develop a framework for deployment and integration of artificial intelligence tools in healthcare. The Blueprint for Resilient Integration and Deployment of Guided Excellence (BRIDGE) is a guideline to facilitate AI adoption in the healthcare industry. == Products and market == Aidoc has developed a suite of artificial intelligence products that flag both time-sensitive and time-consuming (for the radiologist) abnormalities across the body. The algorithms are developed with large quantities of data to provide diagnostic aid for a broad set of pathologies. The company offers an array of algorithms that span across the body, including for intracranial hemorrhage, spine fractures (C, T & L), free air in the abdomen, pulmonary embolism, and more. It developed "Always-on AI", a term coined by Elad Walach that refers to a type of artificial intelligence that is "Always-on—constantly running in the background and automatically analyzing medical imaging data, identifying urgent findings, and sparing radiologists from "drowning" in vast amounts of irrelevant data. Aidoc's solutions cover medical conditions prevalent in all settings (ED/inpatient/outpatient), including level 1 trauma centers, outpatient imaging centers, teleradiology groups and, are set up in over 200 medical centers worldwide. Notable customers include the University of Rochester Medical Center and Global Diagnostics Australia. Aidoc announced in 2024 that its new Clinical AI Reasoning Engine (CARE1) had been submitted for FDA approval. In September 2025 Aidoc received a "Breakthrough Device Designation" from the FDA for a new multi-triage solution that spans numerous acute findings in CT scans. Aidoc's CARE1 foundation model was the basis of the workflow on which the designation was made, enabling simultaneous coverage of multiple pathologies. This new designation allows parallel FDA review of multiple indications under a single submission. In April 2026, Aidoc raised million in a Series E funding round led by Growth Equity at Goldman Sachs Alternatives, with participation from General Catalyst and NVentures. The financing brought the company's total funding to over million. == Clinical Research == A clinical study on Aidoc’ accuracy of deep convolutional neural networks for the detection of pulmonary embolism (PE) on CT pulmonary angiograms (CTPAs) was performed by the University Hospital of Basel and presented at the European Congress of Radiology, showing that the Aidoc algorithm reached 93% sensitivity and 95% specificity. Clinical research has also been performed to test the diagnostic performance of Aidoc's deep learning-based triage system for the flagging of acute findings in abdominal computed tomography (CT) examinations. Overall, the algorithm achieved 93% sensitivity (91/98, 7 false negatives) and 97% specificity (93/96, 3 false-positive) in the detection of acute abdominal findings. Additional clinical research on Aidoc's Intracranial hemorrhage algorithm accuracy was presented at the European Congress of Radiology by Antwerp University Hospital, evaluating the use of its deep learning algorithm for the detection of intracranial hemorrhage on non-contrast enhanced CT of the brain. The University of Washington completed a study on the accuracy of Aidoc's intracranial hemorrhage algorithm.
Web data integration
Web data integration (WDI) is the process of aggregating and managing data from different websites into a single, homogeneous workflow. This process includes data access, transformation, mapping, quality assurance and fusion of data. Data that is sourced and structured from websites is referred to as "web data". WDI is an extension and specialization of data integration that views the web as a collection of heterogeneous databases. Data integration techniques in the context of the web, forms the foundation for businesses taking advantage of data available on the ever-increasing number of publicly-accessible websites. Corporate spending on this area amounted to about USD 2.5bn in 2017, and it is expected that by 2020 the market will reach almost USD 7bn.
Umbrella review
In medical research, an umbrella review is a review of systematic reviews or meta-analyses. They may also be called overviews of reviews, reviews of reviews, summaries of systematic reviews, or syntheses of reviews. Umbrella reviews are among the highest levels of evidence currently available in medicine. By summarizing information from multiple overview articles, umbrella reviews make it easier to review the evidence and allow for comparison of results between each of the individual reviews. Umbrella reviews may address a broader question than a typical review, such as discussing multiple different treatment comparisons instead of only one. They are especially useful for developing guidelines and clinical practice, and when comparing competing interventions.
Articulatory speech recognition
Articulatory speech recognition means the recovery of speech (in forms of phonemes, syllables or words) from acoustic signals with the help of articulatory modeling or an extra input of articulatory movement data. Speech recognition (or automatic speech recognition, acoustic speech recognition) means the recovery of speech from acoustics (sound wave) only. Articulatory information is extremely helpful when the acoustic input is in low quality, perhaps because of noise or missing data. Measurable information from the articulatory system (e.g. tongue, jaw movements) can supplement acoustic signals to improve phone recognition accuracy by 2%. However, attempts to estimate articulatory data from acoustic signals alone have not significantly enhanced recognition performance.
Concordance (publishing)
A concordance is an alphabetical list of the principal words used in a book or body of work, listing every instance of each word with its immediate context. Historically, concordances have been compiled only for works of special importance, such as the Vedas, Bible, Qur'an or the works of Shakespeare, James Joyce or classical Latin and Greek authors, because of the time, difficulty, and expense involved in creating a concordance in the pre-computer era. A concordance is more than an index, with additional material such as commentary, definitions and topical cross-indexing which makes producing one a labor-intensive process even when assisted by computers. In the precomputing era, search technology was unavailable, and a concordance offered readers of long works such as the Bible something comparable to search results for every word that they would have been likely to search for. Today, the ability to combine the result of queries concerning multiple terms (such as searching for words near other words) has reduced interest in concordance publishing. In addition, mathematical techniques such as latent semantic indexing have been proposed as a means of automatically identifying linguistic information based on word context. A bilingual concordance is a concordance based on aligned parallel text. A topical concordance is a list of subjects that a book covers (usually The Bible), with the immediate context of the coverage of those subjects. Unlike a traditional concordance, the indexed word does not have to appear in the verse. The best-known topical concordance is Nave's Topical Bible. The first Bible concordance was compiled for the Vulgate Bible by Hugh of St Cher (d.1262), who employed 500 friars to assist him. In 1448, Rabbi Mordecai Nathan completed a concordance to the Hebrew Bible. It took him ten years. A concordance to the Greek New Testament was published in 1546 by Sixt Birck, and the Septuagint was done a by Conrad Kircher in 1602. The first concordance to the English Bible was published in 1550 by John Merbecke. According to Cruden, it did not employ the verse numbers devised by Robert Stephens in 1545, but "the pretty large concordance" of Mr Cotton did. Then followed Cruden's Concordance and Strong's Concordance. == Use in linguistics == Concordances are frequently used in linguistics, when studying a text. For example: comparing different usages of the same word analysing keywords analysing word frequencies finding and analysing phrases and idioms finding translations of subsentential elements, e.g. terminology, in bitexts and translation memories creating indexes and word lists (also useful for publishing) Concordancing techniques are widely used in national text corpora such as American National Corpus (ANC), British National Corpus (BNC), and Corpus of Contemporary American English (COCA) available on-line. Stand-alone applications that employ concordancing techniques are known as concordancers or more advanced corpus managers. Some of them have integrated part-of-speech taggers (POS taggers) and enable the user to create their own POS-annotated corpora to conduct various types of searches adopted in corpus linguistics. == Inversion == The reconstruction of the text of some of the Dead Sea Scrolls involved a concordance. Access to some of the scrolls was governed by a "secrecy rule" that allowed only the original International Team or their designates to view the original materials. After the death of Roland de Vaux in 1971, his successors repeatedly refused to even allow the publication of photographs to other scholars. This restriction was circumvented by Martin Abegg in 1991, who used a computer to "invert" a concordance of the missing documents made in the 1950s which had come into the hands of scholars outside of the International Team, to obtain an approximate reconstruction of the original text of 17 of the documents. This was soon followed by the release of the original text of the scrolls.