BioCreAtIvE (A critical assessment of text mining methods in molecular biology) consists in a community-wide effort for evaluating information extraction and text mining developments in the biological domain. It was preceded by the Knowledge Discovery and Data Mining (KDD) Challenge Cup for detection of gene mentions. == Community Challenges == === First edition (2004-2005) === Three main tasks were posed at the first BioCreAtIvE challenge: the entity extraction task, the gene name normalization task, and the functional annotation of gene products task. The data sets produced by this contest serve as a Gold Standard training and test set to evaluate and train Bio-NER tools and annotation extraction tools. === Second edition (2006-2007) === The second BioCreAtIvE challenge (2006-2007) had also 3 tasks: detection of gene mentions, extraction of unique idenfiers for genes and extraction information related to physical protein-protein interactions. It counted with participation of 44 teams from 13 countries. === Third edition (2011-2012) === The third edition of BioCreative included for the first time the InterActive Task (IAT), designed to evaluate the practical usability of text mining tools in real-world biocuration tasks. === Fifth edition (2016) === BioCreative V had 5 different tracks, including an interactive task (IAT) for usability of text mining systems and a track using the BioC format for curating information for BioGRID.
NHS COVID-19
NHS COVID-19 was a voluntary contact tracing app for monitoring the spread of the COVID-19 pandemic in England and Wales, in use from 24 September 2020 until 27 April 2023. It was available for Android and iOS smartphones, and could be used by anyone aged 16 or over. Two versions of the app were created. The first was commissioned by NHSX and developed by the Pivotal division of American software company VMware. A pilot deployment began in May 2020, but on 18 June development of the app was abandoned in favour of a second design using the Apple/Google Exposure Notification system. Scotland and Northern Ireland had separate contact tracing apps. A 2023 study estimated that in its first year of use, the app's contact tracing function prevented an estimated 1 million cases, and 9,600 deaths. == Description == The app allowed users to: See the alert level of their local authority area (in Wales) or information about restrictions (in England); to enable this, the user must enter the first half of their postcode "Check in" at places displaying an NHS QR code poster (no longer required by legislation after 26 January 2022, removed from the app the next month) Be notified when they have been in close contact with someone who has tested positive for the virus Be notified when local health protection teams determine that people with the virus had attended a business or other venue around the same time as the user Check their symptoms, and book a coronavirus test if necessary If asked to self-isolate, receive information and a daily "countdown". At first, "close contact" was defined as being within 2 metres for 15 minutes, or within 4 metres for a longer time. These time durations were reduced from 29 October 2020, to as little as three minutes when the other person is at their most infectious, i.e. soon after they begin showing symptoms. === Implementation === The Android app was coded in Kotlin, and the iOS app in Swift. The backend used Java and is deployed to Amazon Web Services using Terraform. The code of the app and back-end is open-source and available on GitHub. == Context == The app was part of the UK's test and trace programme which was chaired by Dido Harding; from 12 May 2020 Tom Riordan, chief executive of Leeds City Council, led the tracing effort. == First phase and cancellation == === Description === In March 2020, NHSX commissioned a contact tracing app to monitor the spread in the United Kingdom of the coronavirus disease 2019 (COVID-19) in the 2020 pandemic, developed by the Pivotal division of American software company VMware. The app used a centralised approach, in contrast to the Google / Apple contact tracing project. NHSX consulted ethicists and GCHQ's National Cyber Security Centre (NCSC) about the privacy aspects. The app recorded the make and model of the phone and asked the user for their postcode area. It generated a unique installation identification number and also a daily identification number. It then used Bluetooth Low Energy (BLE) to record the daily identification number of other users nearby. If a user was unwell, they could tell the app about symptoms which are characteristic of COVID-19, such as a fever and cough. These details were then passed to a central NHS server. This would assess the information and notify other users that have been in contact, giving them appropriate advice such as physical distancing. The NHS would also arrange for a swab test of the unwell user and the outcome would determine further notifications to contacts: if the test confirmed infection with COVID-19, the contacts would be asked to isolate. By June 2020, £11.8 million had been spent on the app; in 2020–21, £35 million was spent on the app. === Deployment === The first public trial of the app began on the Isle of Wight on 5 May 2020 and by 11 May it had been downloaded 55,000 times. When the first national contact tracing schemes were launched – Test, Trace, Protect in Wales on 13 May, then on 28 May NHS Test and Trace in England, and Test and Protect in Scotland – the app was not ready to be included. Replying to a question at the government's daily briefing on 8 June, Hancock was unable to give a date for rollout of the app in England, saying it would be brought in "when it's right to do so". On 17 June, Lord Bethell, junior minister for Innovation at the Department of Health and Social Care, said "we're seeking to get something going before the winter ... it isn't a priority for us at the moment". On 18 June, Health Secretary Matt Hancock announced development would switch to the Apple/Google system after admitting that Apple's restrictions on usage of Bluetooth prevented the app from working effectively. At the same press briefing Dido Harding, leader of the UK's test and trace programme, said "What we've done in really rigorously testing both our own Covid-19 app and the Google-Apple version is demonstrate that none of them are working sufficiently well enough to be actually reliable to determine whether any of us should self-isolate for two weeks [and] that's true across the world". === Concerns === The first, ultimately rejected, version of the app was subject to privacy concerns, the government backtracking on initial statements that the data collected from the app would not be shared outside the NHS. Matthew Gould, CEO of NHSX, the government department responsible for the app, said the data would be accessible to other organisations, but did not disclose which. Data collected would not necessarily be anonymised and would be held in a centralised repository. Over 150 of the UK's security and privacy experts warned the app's data could be used by 'a bad actor (state, private sector, or hacker)' to spy on citizens. Fears were discussed by the House of Commons' Human Rights Select Committee about plans for the app to record user location data. Parliament's Joint Committee on Human Rights said this version of the app should not be released without proper privacy protections. The second version of the app, released nationwide, addressed these concerns by employing a decentralised framework, the Apple/Google Exposure Notification system. Under this system, users remain pseudonymous: a person diagnosed with COVID-19 does not know which people are informed about an encounter, and contacted persons do not receive any information about the person diagnosed with COVID-19. The functionality of the app was also questioned in late April and early May 2020, as the software's use of Bluetooth required the app to be constantly running, meaning users could not use other apps or lock their device if the app was to function properly. The developers of the app were said to have found a way of working around this restriction. === Related contracts === Faculty – a company linked to Cambridge Analytica – provided research and modelling to NHSX in support of the response to the pandemic. Palantir, also linked to Cambridge Analytica, provided their data management platform. These contracts began in February and March respectively. == Second phase == As outlined on cancellation of the first app on 18 June 2020, the Department of Health and Social Care published on 30 July a brief description of the "next phase" app. Users would be able to scan a QR code at venues they visit, and later be notified if they had visited a place which was the source of a number of infections; the app would also assist with identifying symptoms and ordering a test. By using the Exposure Notification system from Apple and Google, personal data would be decentralised. Zuhlke Engineering Ltd, the UK branch of Swiss-based Zühlke Group, used 70 staff to complete the development of the app in 12 weeks. Zuhlke Engineering was awarded "Development Team of the Year" title at UK IT Industry awards in November 2021 for development of NHS COVID-19 application. === Timeline === Testing of the app by NHS volunteer responders, and selected residents of the Isle of Wight and the London Borough of Newham, began around 13 August. The app was made available to the public (aged 16 or over) in England and Wales on 24 September. An updated app released on 29 October, in part from collaboration with the Alan Turing Institute, improved the accuracy of measurements of the distance between the user's phone and other phones. At the same time, the duration threshold for determining exposure was reduced; this was expected to lead to an increase in the number of users told to self-isolate. An update to the app in April 2021, timed to coincide with easing of restrictions on hospitality businesses, was blocked by Apple and Google. It was intended that users who tested positive would be asked to share their history of visited venues, to assist in warning others, but this would have contravened assurances by Apple and Google that location data from devices would not be shared. === Statistics and effectiveness === The app was downloaded six million times on the first day it was generally availa
Shorty Awards
The Shorty Awards (also known as "The Shortys") are awards for outstanding and innovative work in digital and social media content by brands, advertising agencies, and creators. The awards, which generally focus on short-term content, honor achievements in content creation on Twitter, Facebook, YouTube, Instagram, TikTok, Twitch, and other social networking sites. The Shorty Awards began in 2008 and initially recognized achievements by independent creators on Twitter, with the first formal awards ceremony occurring in February 2009. Since then, the awards, which are now awarded each spring, have shifted their focus to recognize content across numerous platforms. Entrant work is judged on the merits of excellence in creativity, strategy, and engagement by the Real Time Academy, a group of industry professionals selected by the Shorty Awards on the basis of their professional reputations, industry knowledge, and personal achievements (which may include previous Shorty wins). An additional public voting component, known as Audience Honor Voting, is also used to select Shorty Awards contenders. Notable Shorty Award winners include Malala Yousafzai, Trevor Noah, Michelle Obama, Conan O’Brien, Lady Gaga, Bill Nye, Jacob Reed, and Lizzo. Brands and organizations such as Chipotle, Duolingo, Marvel Studios, HBO, Red Bull, Airbnb, Nestle, BMW, UNICEF and the Human Rights Campaign have also been awarded. The Shorty Awards also produces an annual award program called The Shorty Impact Awards, a competition dedicated to showcasing digital and social media-based projects by brands, agencies, and organizations that seek to make the world a better place. == List of ceremonies == == 1st Shorty Awards == The awards were created in 2008 by tech entrepreneurs Greg Galant, Adam Varga, and Lee Semel of Sawhorse Media. They invited Twitter account holders to nominate the best Twitter users in general categories such as humor, news, food, and design. Winners were chosen by more than 30,000 Twitter users during the voting period. The founders of Twitter first heard about the awards after the contest had gotten underway and expressed support for it. The first Shorty Awards ceremony was held on February 11, 2009, at the Galapagos Art Space in Brooklyn, New York. Approximately 300 people attended the event. The event was hosted by CNN anchor Rick Sanchez and featured appearances by prominent Twitter users MC Hammer and Gary Vaynerchuk and a video appearance by Shaquille O'Neal. The awards, in 26 categories, were voted on by Twitter users. == 2nd Shorty Awards == Voting for the second Shorty Awards opened in January 2010 in 26 official categories. A Real-Time Photo of the Year category was added to the list of official categories for the first time, recognizing the best photo posted to services such as Twitpic, Yfrog, or Facebook. The second Shorty Awards competition introduced a panel of judges called the Real-Time Academy of Short Form Arts & Sciences whose members were Craig Newmark, David Pogue, Kurt Andersen, Caterina Fake, Joi Ito, Frank Moss, Alberto Ibargüen, Sreenath Sreenivasan, MC Hammer, Alyssa Milano and Jimmy Wales. After public nominations determined the finalists, the academy decided on the winners. Winners were announced at a ceremony held in the Times Center in The New York Times building in Manhattan that was also streamed online. The ceremony was hosted by CNN anchor Rick Sanchez, who presented awards in the official categories as well as the newly added Real-Time Photo of the Year and a special humanitarian award. == 3rd Shorty Awards == The nomination period for the third annual Shorty Awards opened in January 2011 and ran through February 11, 2011, except for new categories that had extended nomination deadlines. There were 30 official categories and five special categories. In addition to Real-Time Photo of the Year, for the first time the awards accepted nominations for Foursquare Mayor of the Year, Foursquare Location of the Year, Microblog of the Year on Tumblr, and a Connecting People award. The awards also introduced new Shorty Industry Awards to recognize the best uses of social media by brands and agencies. Winners were announced at a ceremony on March 28, 2011, hosted by Aasif Mandvi in the Times Center. Other Shorty Awards presenters were scheduled to include Kiefer Sutherland, Jerry Stiller, Anne Meara, Stephen Wallem, Miss USA Rima Fakih, and Miss Teen USA Kamie Crawford. == 4th Shorty Awards == The 4th Annual Shorty Awards featured Ricky Gervais and Tiffani Thiessen. 1.6 million tweeted nominations were made across all the categories to honor the top users on Twitter, Facebook, Tumblr, Foursquare, YouTube and other internet platforms. == 5th Shorty Awards == The 5th Annual Shorty Awards ceremony featured Felicia Day, James Urbaniak, Kristian Nairn, Hannibal Buress, Carrie Keagan, Chris Hardwick, David Karp and Coco Rocha. 2.4 million tweeted nominations were made across all the categories to honor the top users on Twitter, Facebook, Tumblr, Foursquare, YouTube and other internet sites. == 6th Shorty Awards == The ceremony took place on April 7, 2014, at the New York TimesCenter and was hosted by Comedian Natasha Leggero. The show included appearances by Patton Oswalt, Jamie Oliver, Kristen Bell, Jerry Seinfeld, Moshe Kasher, Julie Klausner, Erin Brady, Guy Kawasaki, Matt Walsh, Retta, Us the Duo, Big Boi, Gilbert Gottfried, Thomas Middleditch, Billie Jean King and Leandra Medine. Winners included Jerry Seinfeld and Will Ferrell. == 7th Shorty Awards == The Seventh Annual Shorty Awards was hosted by comedian Rachel Dratch and took place on April 20, 2015, at The Times Center in NYC. The Real-Time Academy, the judging body of the Shortys, tripled in size for the 7th annual Awards and included Alton Brown, Mamrie Hart, Nikki Glaser, OK Go, The Fine Bros, Debbie Sterling, Dan Savage, Deena Varshavskaya and Palmer Luckey. Panic! at the Disco was the musical guest at the ceremony. On-stage presenters included Kevin Jonas, Bill Nye, Bella Thorne, Wyclef Jean, Emily Kinney and Tyler Oakley. == 8th Shorty Awards == The Eighth Annual Shorty Awards were held in NYC at the TimesCenter on April 11, 2016. They were hosted by YouTuber, Writer and Comedian Mamrie Hart with musical performances from Nico & Vinz. Winners of the night included Bill Wurtz, DJ Khaled, Misty Copeland, Casey Neistat, Dwayne Johnson, Hannah Hart, Troye Sivan, Baddie Winkle, Kevin Hart, Taraji P. Henson, King Bach, and Zach King. == 9th Shorty Awards == The Ninth Annual Shorty Awards were held in NYC at the PlayStation Theater on April 23, 2017. They were hosted by two-time Emmy Award winner Tony Hale with a musical performance by Lizzo. Winners of the night included Bill Nye, Shay Mitchell, Doug the Pug, Gigi Gorgeous, Simone Biles, Mara Wilson, Gaten Matarazzo and Chrissy Teigen. == 10th Shorty Awards == The 10th Annual Shorty Awards, took place on April 15, 2018, at the PlayStation Theater, New York City. The ceremony was hosted by actress, singer, and songwriter Keke Palmer with a musical performance by Betty Who. == 11th Shorty Awards == The 11th Annual Shorty Awards were held on May 5, 2019, in New York City at the PlayStation Theater. The ceremony was hosted by American actress and comedian Kathy Griffin, with a musical performance by Tank and the Bangas. == 12th Shorty Awards == The 12th Annual Shorty Awards were held on May 3, 2020. Due to the COVID-19 pandemic, the ceremony took place online for the first time, with presenters and award winners filming from their own homes. The ceremony was hosted by actor J.B. Smoove and featured a remixed performance of Trap Queen by Fetty Wap. Award winners included Jack Stauber, Supercar Blondie, Rose and Rosie, and Greta Thunberg. == 13th Shorty Awards == The 13th Annual Shorty Awards took place from April 26 to May 14, 2021. The ceremony was hosted on different social media platforms, such as Instagram and Clubhouse, to create a more tailored experience. Winners were announced from May 11 to May 14, with 10 winners being revealed each hour from 1 to 4 p.m. EST on the Shorty Awards Instagram account. == 14th Shorty Awards == The 14th Annual Shorty Awards were held virtually on May 15, 2022, honoring the best in social media and digital content. Hosted by Jay Shetty, the event recognized influencers, brands, and organizations across various categories, celebrating excellence in digital storytelling and innovative online campaigns. Notable winners included Tabitha Brown for her food content and the D'Amelio Family for their contributions to family and parenting content. The event highlighted the role of digital media in connecting and inspiring audiences during challenging times. == 15th Shorty Awards == The 15th Annual Shorty Awards celebrated the best in social media and digital content on May 24, 2023, at Tribeca 360° in New York City. Hosted by Jay Pharoah, the event honored creators, brands, and organizations ac
Content format
A content format is an encoded format for converting a specific type of data to displayable information. Content formats are used in recording and transmission to prepare data for observation or interpretation. This includes both analog and digitized content. Content formats may be recorded and read by either natural or manufactured tools and mechanisms. In addition to converting data to information, a content format may include the encryption and/or scrambling of that information. Multiple content formats may be contained within a single section of a storage medium (e.g. track, disk sector, computer file, document, page, column) or transmitted via a single channel (e.g. wire, carrier wave) of a transmission medium. With multimedia, multiple tracks containing multiple content formats are presented simultaneously. Content formats may either be recorded in secondary signal processing methods such as a software container format (e.g. digital audio, digital video) or recorded in the primary format (e.g. spectrogram, pictogram). Observable data is often known as raw data, or raw content. A primary raw content format may be directly observable (e.g. image, sound, motion, smell, sensation) or physical data which only requires hardware to display it, such as a phonographic needle and diaphragm or a projector lamp and magnifying glass. The following are examples of some common content formats and content format categories (covering: sensory experience, model, and language used for encoding information):
Computer network
In computer science, computer engineering, and telecommunications, a network is a group of communicating computers and peripherals known as hosts, which communicate data to other hosts via communication protocols, as facilitated by networking hardware. Within a computer network, hosts are identified by network addresses, which allow networking hardware to locate and identify hosts. Hosts may also have hostnames, memorable labels for the host nodes, which can be mapped to a network address using a hosts file or a name server such as Domain Name Service. The physical medium that supports information exchange includes wired media like copper cables, optical fibers, and wireless radio-frequency media. The arrangement of hosts and hardware within a network architecture is known as the network topology. The first computer network was created in 1940 when George Stibitz connected a terminal at Dartmouth to his Complex Number Calculator at Bell Labs in New York. Today, almost all computers are connected to a computer network, such as the global Internet or embedded networks such as those found in many modern electronic devices. Many applications have only limited functionality unless they are connected to a network. Networks support applications and services, such as access to the World Wide Web, digital video and audio, application and storage servers, printers, and email and instant messaging applications. == History == === Early origins (1940 – 1960s) === In 1940, George Stibitz of Bell Labs connected a teletype at Dartmouth to a Bell Labs computer running his Complex Number Calculator to demonstrate the use of computers at long distance. This was the first real-time, remote use of a computing machine. In the late 1950s, a network of computers was built for the U.S. military Semi-Automatic Ground Environment (SAGE) radar system using the Bell 101 modem. It was the first commercial modem for computers, released by AT&T Corporation in 1958. The modem allowed digital data to be transmitted over regular unconditioned telephone lines at a speed of 110 bits per second (bit/s). In 1959, Christopher Strachey filed a patent application for time-sharing in the United Kingdom and John McCarthy initiated the first project to implement time-sharing of user programs at MIT. Strachey passed the concept on to J. C. R. Licklider at the inaugural UNESCO Information Processing Conference in Paris that year. McCarthy was instrumental in the creation of three of the earliest time-sharing systems (the Compatible Time-Sharing System in 1961, the BBN Time-Sharing System in 1962, and the Dartmouth Time-Sharing System in 1963). In 1959, Anatoly Kitov proposed to the Central Committee of the Communist Party of the Soviet Union a detailed plan for the re-organization of the control of the Soviet armed forces and of the Soviet economy on the basis of a network of computing centers. Kitov's proposal was rejected, as later was the 1962 OGAS economy management network project. During the 1960s, Paul Baran and Donald Davies independently invented the concept of packet switching for data communication between computers over a network. Baran's work addressed adaptive routing of message blocks across a distributed network, but did not include routers with software switches, nor the idea that users, rather than the network itself, would provide the reliability. Davies' hierarchical network design included high-speed routers, communication protocols and the essence of the end-to-end principle. The NPL network, a local area network at the National Physical Laboratory (United Kingdom), pioneered the implementation of the concept in 1968-69 using 768 kbit/s links. Both Baran's and Davies' inventions were seminal contributions that influenced the development of computer networks. === ARPANET (1969 – 1974) === In 1962 and 1963, J. C. R. Licklider sent a series of memos to office colleagues discussing the concept of the "Intergalactic Computer Network", a computer network intended to allow general communications among computer users. This ultimately became the basis for the ARPANET, which began in 1969. That year, the first four nodes of the ARPANET were connected using 50 kbit/s circuits between the University of California at Los Angeles, the Stanford Research Institute, the University of California, Santa Barbara, and the University of Utah. Designed principally by Bob Kahn, the network's routing, flow control, software design and network control were developed by the IMP team working for Bolt Beranek & Newman. In the early 1970s, Leonard Kleinrock carried out mathematical work to model the performance of packet-switched networks, which underpinned the development of the ARPANET. His theoretical work on hierarchical routing in the late 1970s with student Farouk Kamoun remains critical to the operation of the Internet today. In 1973, Peter Kirstein put internetworking into practice at University College London (UCL), connecting the ARPANET to British academic networks, the first international heterogeneous computer network. That same year, Robert Metcalfe wrote a formal memo at Xerox PARC describing Ethernet, a local area networking system he created with David Boggs. It was inspired by the packet radio ALOHAnet, started by Norman Abramson and Franklin Kuo at the University of Hawaii in the late 1960s. Metcalfe and Boggs, with John Shoch and Edward Taft, also developed the PARC Universal Packet for internetworking. That year, the French CYCLADES network, directed by Louis Pouzin was the first to make the hosts responsible for the reliable delivery of data, rather than this being a centralized service of the network itself. === The internet (1974 – present) === In 1974, Vint Cerf and Bob Kahn published their seminal 1974 paper on internetworking, A Protocol for Packet Network Intercommunication. Later that year, Cerf, Yogen Dalal, and Carl Sunshine wrote the first Transmission Control Protocol (TCP) specification, RFC 675, coining the term Internet as a shorthand for internetworking. In July 1976, Metcalfe and Boggs published their paper "Ethernet: Distributed Packet Switching for Local Computer Networks" and in December 1977, together with Butler Lampson and Charles P. Thacker, they received U.S. patent 4063220A for their invention. In 1976, John Murphy of Datapoint Corporation created ARCNET, a token-passing network first used to share storage devices. In 1979, Robert Metcalfe pursued making Ethernet an open standard. In 1980, Ethernet was upgraded from the original 2.94 Mbit/s protocol to the 10 Mbit/s protocol, which was developed by Ron Crane, Bob Garner, Roy Ogus, Hal Murray, Dave Redell and Yogen Dalal. In 1986, the National Science Foundation (NSF) launched the National Science Foundation Network (NSFNET) as a general-purpose research network connecting various NSF-funded sites to each other and to regional research and education networks. In 1995, the transmission speed capacity for Ethernet increased from 10 Mbit/s to 100 Mbit/s. By 1998, Ethernet supported transmission speeds of 1 Gbit/s. Subsequently, higher speeds of up to 800 Gbit/s were added (as of 2025). The scaling of Ethernet has been a contributing factor to its continued use. In the 1980s and 1990s, as embedded systems were becoming increasingly important in factories, cars, and airplanes, network protocols were developed to allow the embedded computers to communicate. In the late 1990s and 2000s, ubiquitous computing and an Internet of Things became popular. === Commercial usage === In 1960, the commercial airline reservation system semi-automatic business research environment (SABRE) went online with two connected mainframes. In 1965, Western Electric introduced the first widely used telephone switch that implemented computer control in the switching fabric. In 1972, commercial services were first deployed on experimental public data networks in Europe. Public data networks in Europe, North America and Japan began using X.25 in the late 1970s and interconnected with X.75. This underlying infrastructure was used for expanding TCP/IP networks in the 1980s. In 1977, the first long-distance fiber network was deployed by GTE in Long Beach, California. == Hardware == === Network links === The transmission media used to link devices to form a computer network include electrical cable, optical fiber, and free space. In the OSI model, the software to handle the media is defined at layers 1 and 2 — the physical layer and the data link layer. Common examples of networking technologies include: Ethernet is a widely adopted family of networking technologies that use copper and fiber media in local area networks (LAN). The media and protocol standards that enable communication between networked devices over Ethernet are defined by IEEE 802.3. Wireless LAN standards, which use radio waves. Some standards use infrared signals as a transmission medium. Power line communication uses a building's power cabling to transmit
Point distribution model
The point distribution model is a model for representing the mean geometry of a shape and some statistical modes of geometric variation inferred from a training set of shapes. == Background == The point distribution model concept has been developed by Cootes, Taylor et al. and became a standard in computer vision for the statistical study of shape and for segmentation of medical images where shape priors really help interpretation of noisy and low-contrasted pixels/voxels. The latter point leads to active shape models (ASM) and active appearance models (AAM). Point distribution models rely on landmark points. A landmark is an annotating point posed by an anatomist onto a given locus for every shape instance across the training set population. For instance, the same landmark will designate the tip of the index finger in a training set of 2D hands outlines. Principal component analysis (PCA), for instance, is a relevant tool for studying correlations of movement between groups of landmarks among the training set population. Typically, it might detect that all the landmarks located along the same finger move exactly together across the training set examples showing different finger spacing for a flat-posed hands collection. == Details == First, a set of training images are manually landmarked with enough corresponding landmarks to sufficiently approximate the geometry of the original shapes. These landmarks are aligned using the generalized procrustes analysis, which minimizes the least squared error between the points. k {\displaystyle k} aligned landmarks in two dimensions are given as X = ( x 1 , y 1 , … , x k , y k ) {\displaystyle \mathbf {X} =(x_{1},y_{1},\ldots ,x_{k},y_{k})} . It's important to note that each landmark i ∈ { 1 , … k } {\displaystyle i\in \lbrace 1,\ldots k\rbrace } should represent the same anatomical location. For example, landmark #3, ( x 3 , y 3 ) {\displaystyle (x_{3},y_{3})} might represent the tip of the ring finger across all training images. Now the shape outlines are reduced to sequences of k {\displaystyle k} landmarks, so that a given training shape is defined as the vector X ∈ R 2 k {\displaystyle \mathbf {X} \in \mathbb {R} ^{2k}} . Assuming the scattering is gaussian in this space, PCA is used to compute normalized eigenvectors and eigenvalues of the covariance matrix across all training shapes. The matrix of the top d {\displaystyle d} eigenvectors is given as P ∈ R 2 k × d {\displaystyle \mathbf {P} \in \mathbb {R} ^{2k\times d}} , and each eigenvector describes a principal mode of variation along the set. Finally, a linear combination of the eigenvectors is used to define a new shape X ′ {\displaystyle \mathbf {X} '} , mathematically defined as: X ′ = X ¯ + P b {\displaystyle \mathbf {X} '={\overline {\mathbf {X} }}+\mathbf {P} \mathbf {b} } where X ¯ {\displaystyle {\overline {\mathbf {X} }}} is defined as the mean shape across all training images, and b {\displaystyle \mathbf {b} } is a vector of scaling values for each principal component. Therefore, by modifying the variable b {\displaystyle \mathbf {b} } an infinite number of shapes can be defined. To ensure that the new shapes are all within the variation seen in the training set, it is common to only allow each element of b {\displaystyle \mathbf {b} } to be within ± {\displaystyle \pm } 3 standard deviations, where the standard deviation of a given principal component is defined as the square root of its corresponding eigenvalue. PDM's can be extended to any arbitrary number of dimensions, but are typically used in 2D image and 3D volume applications (where each landmark point is R 2 {\displaystyle \mathbb {R} ^{2}} or R 3 {\displaystyle \mathbb {R} ^{3}} ). == Discussion == An eigenvector, interpreted in euclidean space, can be seen as a sequence of k {\displaystyle k} euclidean vectors associated to corresponding landmark and designating a compound move for the whole shape. Global nonlinear variation is usually well handled provided nonlinear variation is kept to a reasonable level. Typically, a twisting nematode worm is used as an example in the teaching of kernel PCA-based methods. Due to the PCA properties: eigenvectors are mutually orthogonal, form a basis of the training set cloud in the shape space, and cross at the 0 in this space, which represents the mean shape. Also, PCA is a traditional way of fitting a closed ellipsoid to a Gaussian cloud of points (whatever their dimension): this suggests the concept of bounded variation. The idea behind PDMs is that eigenvectors can be linearly combined to create an infinity of new shape instances that will 'look like' the one in the training set. The coefficients are bounded alike the values of the corresponding eigenvalues, so as to ensure the generated 2n/3n-dimensional dot will remain into the hyper-ellipsoidal allowed domain—allowable shape domain (ASD).
Back-Up Interceptor Control
Backup Interceptor Control (BUIC, ) was the Electronic Systems Division 416M System to backup the SAGE 416L System in the United States and Canada. BUIC deployed Cold War command, control, and coordination systems to SAGE radar stations to create dispersed NORAD Control Centers. == Background == Prior to the SAGE Direction Centers becoming operational, the USAF deployed data link systems at NORAD Control Centers with ground computers for controlling crewed interceptors. After SAGE IBM AN/FSQ-7 Combat Direction Centrals became operational and the Super Combat Centers with improved (digital) computers were cancelled, a backup to SAGE was planned in the event the above-ground SAGE Air Defense Direction Center failed. == General Electric AN/GPA-37 Course Directing Group == BUIC began with deployment of General Electric AN/GPA-37 Course Directing Groups to several Long Range Radar stations. Units designated included the "U.S. Air Force 858th Air Defense Group (BUIC) [which became] a permanent operating facility" at Naval Air Station Fallon in Nevada. == BUIC II == BUIC II was used to command and control sites using the Burroughs AN/GSA-51 Radar Course Directing Group. North Truro AFS became the first ADC installation configured for BUIC II. == BUIC III == The AN/GYK-19 (initially AN/GSA-51A) was an upgraded version of the BUIC II system designated AN/GSA-51A and required a larger building than the AN/GSA-51. The first BUIC III site was Fort Fisher AFS, and Air Defense Command's was first installed at Fort Fisher Air Force Station, North Carolina. Although more advanced systems were contemplated, the final design of the BUIC III system was an upgraded version of the BUIC II with around twice the performance. == Closure and upgrade == In 1972, the USAF decided to shut down most of the BUIC sites; most of the sites mothballed by 1974, except for the BUIC III site at Tyndall Air Force Base. In Canada the BUIC site at Senneterre was shut down, but St Margarets remained open. The remaining sites were closed between 1983-1984 when SAGE was replaced by the Joint Surveillance System. The AN/FYQ-47 Common Digitizer for the Joint Surveillance System, and the Radar Video Data Processor (RVDP) was a combined system for the Air Force and Federal Aviation Administration (FAA), it replaced the SAGE Burroughs AN/FST-2 Coordinate Data Transmitting Sets.