Comparing the best AI sales assistant? An AI sales assistant is software that uses machine learning to help you get more done — it lowers the barrier so anyone can produce professional output. Privacy matters too: check whether your data trains the model and whether a no-log or enterprise tier is available. Whether you are a beginner or a pro, the right AI sales assistant slots into your workflow and pays for itself fast. We tested the leading options and ranked them by quality, value, and ease of use.
Coolgorilla
Coolgorilla was one of the earliest software developers that created 3rd party native applications for Apple iPod devices. Coolgorilla was an early adopter of using a sponsorship business model to enable mobile applications to be given away freely. Coolgorilla developed a series of Talking Phrasebooks for iPods in 2006. They partnered with online travel company lastminute.com who sponsored the applications enabling them to be made available to download completely free of charge. As mobile devices became more sophisticated, Coolgorilla developed the Talking Phrasebooks for Sony Ericsson and Nokia Mobile Devices which at the time were considerably noteworthy since the applications used real voice audio translations. With Apple's introduction of the iPhone in 2007, Coolgorilla developed a Web App before having four of the iPhone Talking Phrasebooks available to download from Apple's App Store on the day it opened in 2008. == Almanac in Chronological Order == On 23 December 2005, CoolGorilla, a new start-up, launched a trivia game for the iPod. It was titled "Rock and Pop Quiz". It was a quiz game that tested users' knowledge on bands such as U2, Metallica, Beyonce, and the Beatles. The quiz contained twenty megabytes of audible trivia questions. The free game was compatible with 3rd, 4th and 5th generation iPods, iPod mini and nano. In March 2006, Coolgorilla released "Movie Quiz for iPods" with a price of $5. It was an audio game narrated by New York's DJ Thomas, a radio and television host, voice over artist and event Master of Ceremonies. There were questions on Star Wars, Spiderman, The Godfather, Pulp Fiction, The Matrix, James Bond, and others. The user could keep track of their score. The game included a secret code for players who answered all questions correctly which enabled users to enter their name on the Coolgorilla Hall of Fame. In May 2006, Coolgorilla launched a World Cup Encyclopedia which was released prior to the 2006 FIFA World Cup. It had information on the World Cup schedule, details of every player from every team, every score from every world cup game ever played, stadium details, and manager profiles. It was a free download. In June 2006, Coolgorilla released a series of iPod Phrasebooks in German, Greek, French and Spanish. They were sponsored by lastminute.com and were free. The phrasebooks included common words and phrases for tourists with 750 sound files. They were accessed through the iPod's Notes feature. In April 2007, Coolgorilla released a downloadable version of the Talking Phrasebooks for Nokia and Sony Ericsson mobile devices. French, Spanish, German, Greek, Italian, and Portuguese were produced. The application provided real voice translations. They initially sold for £3 but 3 months later were offered for free. The branding was lastminute.com branding. Apple's iPhone was released at the end of June 2007. Soon after, Coolgorilla released an online all-in-one version of their Talking Phrasebooks for iPhone (Web App). The Phrasebooks were made available online in the form of a web app as iPhone did not yet allow for the download of additional apps. The app provided both text and audio translations in French, Spanish, Portuguese, Italian, German, and Greek. The iPhone translated the phrases using the recordings of real, native voice-over artists. A text translation on screen was also displayed. Apple's App Store opened in July 2008 with approximately 500 native apps available. Four of these Apps were Coolgorilla's Talking Phrasebooks for iPhone (Native Apps). There was French, German, Italian, and Spanish. These Apps carried lastminute.com branding and were available for free download. In the first three weeks following their release, the phrasebooks had over 350,000 downloads. Subsequently, Dutch, Arabic, Mandarin and Cantonese were also released. In October 2008, Coolgorilla released an iPhone London Travel Guide. Coolgorilla featured on NBC News in August 2009. In 2010, FIAT used the Italian Phrasebook to help promote the release of their FIAT 500 in the US. There has been no further activity since.
Single particle analysis
Single particle analysis is a group of related computerized image processing techniques used to analyze images from transmission electron microscopy (TEM). These methods were developed to improve and extend the information obtainable from TEM images of particulate samples, typically proteins or other large biological entities such as viruses. Individual images of stained or unstained particles are very noisy, making interpretation difficult. Combining several digitized images of similar particles together gives an image with stronger and more easily interpretable features. An extension of this technique uses single particle methods to build up a three-dimensional reconstruction of the particle. Using cryo-electron microscopy it has become possible to generate reconstructions with sub-nanometer, near-atomic resolution resolution first in the case of highly symmetric viruses, and now in smaller, asymmetric proteins as well. == Techniques == Single particle analysis can be done on both negatively stained and vitreous ice-embedded transmission electron cryomicroscopy (CryoTEM) samples. Single particle analysis methods are, in general, reliant on the sample being homogeneous, although techniques for dealing with conformational heterogeneity are being developed. Images (micrographs) are taken with an electron microscope using charged-coupled device (CCD) detectors coupled to a phosphorescent layer (in the past, they were instead collected on film and digitized using high-quality scanners). The image processing is carried out using specialized software programs, often run on multi-processor computer clusters. Depending on the sample or the desired results, various steps of two- or three-dimensional processing can be done. === Alignment and classification === Biological samples, and especially samples embedded in thin vitreous ice, are highly radiation sensitive, thus only low electron doses can be used to image the sample. This low dose, as well as variations in the metal stain used (if used) means images have high noise relative to the signal given by the particle being observed. By aligning several similar images to each other so they are in register and then averaging them, an image with higher signal-to-noise ratio can be obtained. As the noise is mostly randomly distributed and the underlying image features constant, by averaging the intensity of each pixel over several images only the constant features are reinforced. Typically, the optimal alignment (a translation and an in-plane rotation) to map one image onto another is calculated by cross-correlation. However, a micrograph often contains particles in multiple different orientations and/or conformations, and so to get more representative image averages, a method is required to group similar particle images together into multiple sets. This is normally carried out using one of several data analysis and image classification algorithms, such as multi-variate statistical analysis and hierarchical ascendant classification, or k-means clustering. Often data sets of tens of thousands of particle images are used, and to reach an optimal solution an iterative procedure of alignment and classification is used, whereby strong image averages produced by classification are used as reference images for a subsequent alignment of the whole data set. === Image filtering === Image filtering (band-pass filtering) is often used to reduce the influence of high and/or low spatial frequency information in the images, which can affect the results of the alignment and classification procedures. This is particularly useful in negative stain images. The algorithms make use of fast Fourier transforms (FFT), often employing Gaussian shaped soft-edged masks in reciprocal space to suppress certain frequency ranges. High-pass filters remove low spatial frequencies (such as ramp or gradient effects), leaving the higher frequencies intact. Low-pass filters remove high spatial frequency features and have a blurring effect on fine details. === Contrast transfer function === Due to the nature of image formation in the electron microscope, bright-field TEM images are obtained using significant underfocus. This, along with features inherent in the microscope's lens system, creates blurring of the collected images visible as a point spread function. The combined effects of the imaging conditions are known as the contrast transfer function (CTF), and can be approximated mathematically as a function in reciprocal space. Specialized image processing techniques such as phase flipping and amplitude correction / Wiener filtering can (at least partially) correct for the CTF, and allow high resolution reconstructions. === Three-dimensional reconstruction === Transmission electron microscopy images are projections of the object showing the distribution of density through the object, similar to medical X-rays. By making use of the projection-slice theorem a three-dimensional reconstruction of the object can be generated by combining many images (2D projections) of the object taken from a range of viewing angles. Proteins in vitreous ice ideally adopt a random distribution of orientations (or viewing angles), allowing a fairly isotropic reconstruction if a large number of particle images are used. This contrasts with electron tomography, where the viewing angles are limited due to the geometry of the sample/imaging set up, giving an anisotropic reconstruction. Filtered back projection is a commonly used method of generating 3D reconstructions in single particle analysis, although many alternative algorithms exist. Before a reconstruction can be made, the orientation of the object in each image needs to be estimated. Several methods have been developed to work out the relative Euler angles of each image. Some are based on common lines (common 1D projections and sinograms), others use iterative projection matching algorithms. The latter works by beginning with a simple, low resolution 3D starting model and compares the experimental images to projections of the model and creates a new 3D to bootstrap towards a solution. Methods are also available for making 3D reconstructions of helical samples (such as tobacco mosaic virus), taking advantage of the inherent helical symmetry. Both real space methods (treating sections of the helix as single particles) and reciprocal space methods (using diffraction patterns) can be used for these samples. === Tilt methods === The specimen stage of the microscope can be tilted (typically along a single axis), allowing the single particle technique known as random conical tilt. An area of the specimen is imaged at both zero and at high angle (~60-70 degrees) tilts, or in the case of the related method of orthogonal tilt reconstruction, +45 and −45 degrees. Pairs of particles corresponding to the same object at two different tilts (tilt pairs) are selected, and by following the parameters used in subsequent alignment and classification steps a three-dimensional reconstruction can be generated relatively easily. This is because the viewing angle (defined as three Euler angles) of each particle is known from the tilt geometry. 3D reconstructions from random conical tilt suffer from missing information resulting from a restricted range of orientations. Known as the missing cone (due to the shape in reciprocal space), this causes distortions in the 3D maps. However, the missing cone problem can often be overcome by combining several tilt reconstructions. Tilt methods are best suited to negatively stained samples, and can be used for particles that adsorb to the carbon support film in preferred orientations. The phenomenon known as charging or beam-induced movement makes collecting high-tilt images of samples in vitreous ice challenging. === Map visualization and fitting === Various software programs are available that allow viewing the 3D maps. These often enable the user to manually dock in protein coordinates (structures from X-ray crystallography, NMR, or a computational model such as one found in the AlphaFold Protein Structure Database) of subunits into the electron density. Several programs can also fit subunits computationally; as of the 2020s using these programs tend to produce better accuracy than manual docking because they can perform labor-intensive tasks such as: The scale of SPA-derived maps depends on knowing the pixel size (angstorms per pixel), which is not always accurate. Programs can automatically correct for this difference by using coordinate data or by using knowledge of chemical bonds. Many proteins are made up of several roughly rigid protein domains linked by flexible parts. Pre-existing coordinate data, whether experimental or computational, may not exactly match the inter-domain positioning of the cyro-EM map. Modern programs can automatically "chop" pre-existing coordinate data into individual domains and fit them in individually. For higher-resolution structures, it is pos
Tresorit
Tresorit is a Swiss company providing end-to-end encrypted cloud storage and secure content collaboration services. Founded in 2011, the company primarily serves businesses and organizations with elevated data protection and compliance requirements. Since 2021, Tresorit has been part of Swiss Post's digital business services, which, under the name 'Swiss Post Digital' offer secure communication platforms and connectable software solutions for SMEs, public authorities, and the healthcare sector, among others. == History == Tresorit was founded in 2011 by Hungarian software developers Istvan Lam, Szilveszter Szebeni and Gyorgy Szilagyi with the aim of providing a secure alternative to traditional cloud storage solutions. The company developed a cloud collaboration platform based on client-side end-to-end encryption and a zero-knowledge architecture. In its early years, Tresorit gained attention through a public security challenge inviting researchers to attempt to compromise its encryption system. The initiative received coverage in technology and cybersecurity media. The company initially positioned itself as a secure alternative to conventional cloud storage services and gradually expanded its offering toward enterprise-focused collaboration tools. In 2021, Swiss Post Communications Services acquired a majority stake in Tresorit. The company is now part of Swiss Post, and continues to operate independently within Swiss Post’s digital division, while benefiting from the broader infrastructure and institutional framework of its parent organization. Tresorit has offices in Zurich, Munich, and Budapest. == Products and Services == Tresorit provides a cloud-based platform for secure file storage and collaboration. Its services include encrypted file sharing, email encryption, electronic signatures, and encrypted data rooms for managing sensitive documents and workflows. The platform is available on Windows, macOS, Linux, Android, and iOS. == Technology == Tresorit uses client-side end-to-end encryption based on a zero-knowledge model. Files are encrypted on the user’s device before being uploaded to company servers. According to the company, encryption keys remain under user control, meaning that Tresorit and third parties cannot access the content of stored files. == Security challenge == Between 2013 and 2014, Tresorit organized a public challenge inviting security researchers to attempt to compromise the service's encryption implementation. The challenge received coverage in technology and cybersecurity media. == Acquisition by Swiss Post == In 2021, Swiss Post Communications Services acquired a majority stake in Tresorit as part of Swiss Post’s broader digital services strategy. The company is now part of Swiss Post. == Reception == Tresorit has been covered by international technology and business publications in the context of secure cloud storage and encrypted collaboration services. TechCrunch described the company as an early European provider of end-to-end encrypted cloud services, while The New York Times included it in discussions of secure file-sharing tools. Other publications such as TechRadar and ITPro have reviewed Tresorit in the context of enterprise security and confidential data handling.
Cumulus (software)
Cumulus is a digital asset management software designed for client/server system which is developed by Canto Software. The product makes use of metadata for indexing, organizing, and searching. == History == Cumulus was first released as a Macintosh application in 1992, and was named by Apple Computer as the "Most Innovative Product of 1992". Cumulus introduced search capabilities beyond those available in the Macintosh at the time, particularly relating to thumbnails. Cumulus 1.0 was a single-user product with no network capabilities. Among the main features of Cumulus 1.0, the search function automatically generated previews and contained support for the included AppleTalk – Peer-to-Peer – network. Cumulus 2.5 was available in five different languages and received the 1993 MacUser magazine Eddy award for "Best Publishing & Graphics Utility". In 1995, Canto introduced the scanner software "Cirrus" to focus on the development of Cumulus. Cumulus 3, released in 1996, introduced a server version for the first time and contained the possibility to spread files over the Internet via the "Web Publisher". Since Apple offered Cumulus 3 with its "Workgroup Server" as a bundle, Cumulus became one of the leading digital asset management systems. Cumulus 4 was the first version that was network-ready, and was available for Macintosh, Windows and UNIX operating systems allowing for cross-platform file sharing. Released in 1998, the support of Solaris was discounted later. Cumulus 5 modified the software core to use an open architecture providing an API to external systems and databases. The open architecture of Cumulus 5 also enabled a more functional bridge between Cumulus and the Internet. Cumulus 6 introduced Embedded Java Plugin (EJP) which allowed system integrators to build custom Java plug-ins in order to extend the functionality of the Cumulus client. Cumulus 6.5 marked the end of the Cumulus Single User Edition product, which was licensed to MediaDex for further development and distribution. Cumulus 7 was introduced summer of 2006. Cumulus 8 was released in June 2009, with new indexing capabilities taking advantage of multicore/multiprocessor systems, and ability to manage a wider variety of file formats. Cumulus 8.5 was released in May 2011. Support was added for multilingual metadata, sometimes referred to as "World Metadata." Cumulus Sites was updated to support metadata editing and file uploads. Cumulus 8.6 was released in July 2012, and contains an updated user interface for the administration of Cumulus Sites and additional features for web-based administration of Cumulus. Other additions include features for collaboration links, multi-language support and automated version control. Cumulus 9 was released in September 2013 and introduced a new Web Client User Interface and the Cumulus Video Cloud. The Cumulus Web Client UI was redesigned to provide users with a modern, easy-to-use interface to support and guide the user while addressing modern business needs. The Cumulus Video Cloud extends the Cumulus video handling capabilities to add conversion and global streaming. Cumulus 9 also saw the addition of upload collection links which allow external collaborators to drag and drop files directly into Cumulus without needing a Cumulus account. Cumulus 9.1 was released in May 2014 and introduced the Adobe Drive Adapter for Cumulus which allows users to browse and search digital assets in Cumulus directly from Adobe work environments such as Photoshop, InDesign, Illustrator, Premier and other Adobe applications. Cumulus 10 (Cumulus X) was released July 2015 and introduced two mobile-friendly products: the Cumulus app and Portals. The Cumulus app on iOS was designed to allow users to collaborate either on an iPhone or iPad. Portals is the read-only version of the Cumulus Web Client where users can work with assets that admins allow. Cumulus 10.1 was introduced in January 2016 and included the InDesign Client integration where users can work with Adobe InDesign while accessing their assets from Cumulus. Cumulus 10.2 was introduced in September 2016 and brought the Media Delivery Cloud using Amazon Web Services (AWS). It allows users to manage their media rendition in a single source and distribute media files globally across different channels and devices. Cumulus 10.2.3 was released in February 2017 and came with a "crop and customize photos" feature for Portals and the Web Client. == Product overview == The cataloging of the file via upload into the archive is where Cumulus transfers maximum information about the file from the metadata. For image or photo files, this is typically Exif and IPTC data. The metadata is mainly used to search the archive. The use of embargo data supports license management for copyrighted material. The managed files can be cataloged and their usage can be set. The indexing is based on a predefined taxonomy, which is governed by the internal rules of the organization or by industry standards. You can specify whether files can only be used for specific purposes or only by certain groups of people. The production management system includes version management for files. Via the publication function, the files can be distributed directly via links or e-mails. It's also possible to access from the outside via the Cumulus Portals web interface, which allows a read access to released content from the catalog. There are different variants, starting with the "Workgroup archive server" up to the "Enterprise Business Server" for large companies. Both server and client are extensible through a Java-based plug-in architecture. Since version 7.0, there is a web application based on Ajax with a separate user interface. For access to the Cumulus catalog on mobile, there has been an application for Apple devices based on iOS since 2010. == Miscellaneous == In 2015, Cumulus developer Canto established the first Canto digital asset management (DAM) event. The event is held annually in Berlin. The Henry Stewart team has been hosting DAM conferences since 2006.
Steerable filter
In image processing, a steerable filter is an orientation-selective filter that can be computationally rotated to any direction. Rather than designing a new filter for each orientation, a steerable filter is synthesized from a linear combination of a small, fixed set of "basis filters". This approach is efficient and is widely used for tasks that involve directionality, such as edge detection, texture analysis, and shape-from-shading. The principle of steerability has been generalized in deep learning to create equivariant neural networks, which can recognize features in data regardless of their orientation or position. == Example == A common example of a steerable filter is the first derivative of a two-dimensional Gaussian function. This filter responds strongly to oriented image features like edges. It is constructed from two basis filters: the partial derivative of the Gaussian with respect to the horizontal direction ( x {\displaystyle x} ) and the vertical direction ( y {\displaystyle y} ). If G ( x , y ) {\displaystyle G(x,y)} is the Gaussian function, and G x {\displaystyle G_{x}} and G y {\displaystyle G_{y}} are its partial derivatives (which measure the rate of change in the x {\displaystyle x} and y {\displaystyle y} directions, respectively), a new filter G θ {\displaystyle G_{\theta }} oriented at an angle θ {\displaystyle \theta } can be synthesized with the formula: G θ = cos ( θ ) G x + sin ( θ ) G y {\displaystyle G_{\theta }=\cos(\theta )G_{x}+\sin(\theta )G_{y}} Here, the basis filters G x {\displaystyle G_{x}} and G y {\displaystyle G_{y}} are weighted by cos ( θ ) {\displaystyle \cos(\theta )} and sin ( θ ) {\displaystyle \sin(\theta )} to "steer" the filter's sensitivity to the desired orientation. This is equivalent to taking the dot product of the direction vector ( cos θ , sin θ ) {\displaystyle (\cos \theta ,\sin \theta )} with the filter's gradient, ( G x , G y ) {\displaystyle (G_{x},G_{y})} . == Generalization in deep learning: Equivariant neural networks == The concept of steerability is foundational to equivariant neural networks, a class of models in deep learning designed to understand symmetries in data. A network is considered equivariant to a transformation (like a rotation) if transforming the input and then passing it through the network produces the same result as passing the input through the network first and then transforming the output. Formally, for a transformation T {\displaystyle T} and a network f {\displaystyle f} , this property is defined as f ( T ( input ) ) = T ( f ( input ) ) {\displaystyle f(T({\text{input}}))=T(f({\text{input}}))} . This built-in understanding of geometry makes models more data-efficient. For example, a network equivariant to rotation does not need to be shown an object in multiple orientations to learn to recognize it; it inherently understands that a rotated object is still the same object. This leads to better generalization and performance, particularly in scientific applications. === Mathematical foundation === Equivariant neural networks use principles from group theory to create operations that respect geometric symmetries, such as the SO(3) group for 3D rotations or the E(3) group for rotations and translations. Instead of learning standard filter kernels, these networks learn how to combine a fixed set of basis kernels. These basis functions are chosen so that they have well-defined behaviors under transformation groups. Spherical harmonics are frequently used as basis functions because they form a complete set of functions that behave predictably under rotation, making them ideal for creating steerable 3D kernels. Features within the network are treated as geometric tensors, which are mathematical objects (like scalars or vectors) that are "typed" by their behavior under transformations. These types correspond to the irreducible representations (irreps) of the group. The tensor product is the fundamental operation used to combine these typed features in a way that preserves equivariance, guaranteeing that the network as a whole respects the desired symmetry. Frameworks like e3nn simplify the construction of these networks by automating the complex mathematics of irreducible representations and tensor products. === Applications === Steerable and equivariant models are highly effective for problems with inherent geometric symmetries. Examples include: Protein structure analysis: SE(3)-equivariant networks can process 3D molecular structures while respecting their rotational and translational symmetries. 3D Point cloud processing: Rotation-equivariant filters built from steerable spherical functions can perform tasks like 3D shape classification. Computational chemistry: E(3)-equivariant graph neural networks are used to model interatomic potentials for molecular dynamics simulations, creating highly accurate and data-efficient models of physical systems.
Act! LLC
ACT! (previously known as Activity Control Technology, Automated Contact Tracking, ACT! by Sage, and Sage ACT!) is a customer relationship management and marketing automation software platform designed for small and medium-sized businesses. It has over 2.8 million registered users as of December 2014. == History == The company Conductor Software was founded in 1986, in Dallas, Texas, by Pat Sullivan and Mike Muhney. The original name for the software was Activity Control Technology; it was renamed to Automated Contact Tracking, later abbreviated to ACT. The name of the company was subsequently changed to Contact Software International and it was sold in 1993 to Symantec Corporation, who in 1999 then sold it to SalesLogix. The Sage Group purchased Interact Commerce (formerly SalesLogix) in 2001 through Best Software, then its North American software division. Swiftpage acquired it in 2013. Beginning with the 2006 version, the name was styled ACT! by Sage, and in 2010 revised to Sage ACT!. Following its 2013 acquisition by Swiftpage, it was renamed to ACT! Swiftpage. In May 2018, ACT! was sold to SFW Advisors. In December 2018, Kuvana, a marketing automation software solution, was acquired by SFW and merged with ACT! This add-on is now a complementary service to the core CRM solution. In December 2019, ACT! hired Steve Oriola as chairman and CEO. In 2020, Swiftpage changed its company name to ACT!. In March 2023, ACT! hired Bruce Reading as President and CEO. == Software == ACT! features include contact, company and opportunity management, a calendar, marketing automation and e-marketing tools, reports, interactive dashboards with graphical visualizations, and the ability to track prospective customers. ACT! integrates with Microsoft Word, Excel, Outlook, Google Contacts, Gmail, and other applications via Zapier. For custom integrations, ACT! has an in-built API. ACT! can be accessed from Windows desktops (Win7 and later) with local or network shared database; synchronized to laptops or remote officers; Citrix or Remote Desktop; Web browsers (Premium only) with self or SaaS hosting; smartphones and tablets via HTML5 Web (Premium only); smartphones and tablets via sync with Handheld Contact.