AI Analytics Healthcare

AI Analytics Healthcare — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

  • Inverse consistency

    Inverse consistency

    In image registration, inverse consistency measures the consistency of mappings between images produced by a registration algorithm. The inverse consistency error, introduced by Christiansen and Johnson in 2001, quantifies the distance between the composition of the mappings from each image to the other, produced by the registration procedure, and the identity function, and is used as a regularisation constraint in the loss function of many registration algorithms to enforce consistent mappings. Inverse consistency is necessary for good image registration but it is not sufficient, since a mapping can be perfectly consistent but not register the images at all. == Definition == Image registration is the process of establishing a common coordinate system between two images, and given two images I 1 : Ω 1 → R I 2 : Ω 2 → R {\displaystyle {\begin{aligned}I_{1}:\Omega _{1}\to \mathbb {R} \\I_{2}:\Omega _{2}\to \mathbb {R} \end{aligned}}} registering a source image I 1 {\displaystyle I_{1}} to a target image I 2 {\displaystyle I_{2}} consists of determining a transformation f 1 : Ω 2 → Ω 1 {\displaystyle f_{1}:\Omega _{2}\to \Omega _{1}} that maps points from the target space to the source space. An ideal registration algorithm should not be sensitive to which image in the pair is used as source or target, and the registration operator should be antisymmetric such that the mappings f 1 : Ω 2 → Ω 1 f 2 : Ω 1 → Ω 2 {\displaystyle {\begin{aligned}f_{1}:\Omega _{2}\to \Omega _{1}\\f_{2}:\Omega _{1}\to \Omega _{2}\end{aligned}}} produced when registering I 1 {\displaystyle I_{1}} to I 2 {\displaystyle I_{2}} and I 2 {\displaystyle I_{2}} to I 1 {\displaystyle I_{1}} respectively should be the inverse of each other, i.e. f 2 = f 1 − 1 {\displaystyle f_{2}=f_{1}^{-1}} and f 1 = f 2 − 1 {\displaystyle f_{1}=f_{2}^{-1}} or, equivalently, f 2 ∘ f 1 = id Ω 2 {\displaystyle f_{2}\circ f_{1}=\operatorname {id} _{\Omega _{2}}} and f 1 ∘ f 2 = id Ω 1 {\displaystyle f_{1}\circ f_{2}=\operatorname {id} _{\Omega _{1}}} , where ∘ {\displaystyle \circ } denotes the function composition operator. Real algorithms are not perfect, and when swapping the role of source and target image in a registration problem the so obtained transformations are not the inverse of each other. Inverse consistency can be enforced by adding to the loss function of the registration a symmetric regularisation term that penalises inconsistent transformations ∫ Ω 2 ‖ f 2 ( f 1 ( x ) ) − x ‖ 2 d x + ∫ Ω 1 ‖ f 1 ( f 2 ( x ) ) − x ‖ 2 d x . {\displaystyle \int _{\Omega _{2}}\left\Vert f_{2}(f_{1}(x))-x\right\Vert ^{2}\mathrm {d} x+\int _{\Omega _{1}}\left\Vert f_{1}(f_{2}(x))-x\right\Vert ^{2}\mathrm {d} x.} Inverse consistency can be used as a quality metric to evaluate image registration results. The inverse consistency error ( I C E {\displaystyle ICE} ) measures the distance between the composition of the two transforms and the identity function, and it can be formulated in terms of both average ( I C E a {\displaystyle ICE_{a}} ) or maximum ( I C E m {\displaystyle ICE_{m}} ) over a region of interest Ω {\displaystyle \Omega } of the image: I C E a = 1 ∫ Ω d x ∫ Ω ‖ f 2 ( f 1 ( x ) ) − x ‖ d x I C E m = max x ∈ Ω ‖ f 2 ( f 1 ( x ) ) − x ‖ . {\displaystyle {\begin{aligned}ICE_{a}&={\frac {1}{\int _{\Omega }\mathrm {d} x}}\int _{\Omega }\left\Vert f_{2}(f_{1}(x))-x\right\Vert \mathrm {d} x\\ICE_{m}&=\max _{x\in \Omega }\left\Vert f_{2}(f_{1}(x))-x\right\Vert .\end{aligned}}} While inverse consistency is a necessary property of good registration algorithms, inverse consistency error alone is not a sufficient metric to evaluate the quality of image registration results, since a perfectly consistent mapping, with no other constraint, may be not even close to correctly register a pair of images.

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  • Incremental heuristic search

    Incremental heuristic search

    Incremental heuristic search algorithms combine both incremental and heuristic search to speed up searches of sequences of similar search problems, which is important in domains that are only incompletely known or change dynamically. Incremental search has been studied at least since the late 1960s. Incremental search algorithms reuse information from previous searches to speed up the current search and solve search problems potentially much faster than solving them repeatedly from scratch. Similarly, heuristic search has also been studied at least since the late 1960s. Heuristic search algorithms, often based on A, use heuristic knowledge in the form of approximations of the goal distances to focus the search and solve search problems potentially much faster than uninformed search algorithms. The resulting search problems, sometimes called dynamic path planning problems, are graph search problems where paths have to be found repeatedly because the topology of the graph, its edge costs, the start vertex or the goal vertices change over time. So far, three main classes of incremental heuristic search algorithms have been developed: The first class restarts A at the point where its current search deviates from the previous one (example: Fringe Saving A). The second class updates the h-values (heuristic, i.e. approximate distance to goal) from the previous search during the current search to make them more informed (example: Generalized Adaptive A). The third class updates the g-values (distance from start) from the previous search during the current search to correct them when necessary, which can be interpreted as transforming the A search tree from the previous search into the A search tree for the current search (examples: Lifelong Planning A, D, D Lite). All three classes of incremental heuristic search algorithms are different from other replanning algorithms, such as planning by analogy, in that their plan quality does not deteriorate with the number of replanning episodes. == Applications == Incremental heuristic search has been extensively used in robotics, where a larger number of path planning systems are based on either D (typically earlier systems) or D Lite (current systems), two different incremental heuristic search algorithms.

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  • Google Clips

    Google Clips

    Google Clips is a discontinued miniature clip-on camera device developed by Google. == History == It was announced on October 4, 2017 and went on sale on January 27, 2018. Google Clips automatically captured video clips (without audio) at moments its machine learning algorithms determined to be interesting or relevant. An indicator flashed when the camera was looking for scenes to capture. Google Clips' artificial intelligence (AI) could learn the faces of people to take photographs with certain people, and could automatically set lighting and framing. It had 16 GB of storage built-in storage and could record clips for up to 3 hours. This camera was originally priced at US$249 in the United States. It was withdrawn from sale on October 15, 2019, but supported until the end of December 2021. == Reception == The Independent wrote that Google Clips is "an impressive little device, but one that also has the potential to feel very creepy." According to The Verge's generally negative review, "it didn't capture anything special" over two weeks of testing.

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  • Journal of Machine Learning Research

    Journal of Machine Learning Research

    The Journal of Machine Learning Research is a peer-reviewed open access scientific journal covering machine learning. It was established in 2000 and the first editor-in-chief was Leslie Kaelbling. The current editors-in-chief are Francis Bach (Inria) and David Blei (Columbia University). == History == The journal was established as an open-access alternative to the journal Machine Learning. In 2001, forty editorial board members of Machine Learning resigned, saying that in the era of the Internet, it was detrimental for researchers to continue publishing their papers in expensive journals with pay-access archives. The open access model employed by the Journal of Machine Learning Research allows authors to publish articles for free and retain copyright, while archives are freely available online. Print editions of the journal were published by MIT Press until 2004 and by Microtome Publishing thereafter. From its inception, the journal received no revenue from the print edition and paid no subvention to MIT Press or Microtome Publishing. In response to the prohibitive costs of arranging workshop and conference proceedings publication with traditional academic publishing companies, the journal launched a proceedings publication arm in 2007 and now publishes proceedings for several leading machine learning conferences, including the International Conference on Machine Learning, COLT, AISTATS, and workshops held at the Conference on Neural Information Processing Systems.

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  • Fling (social network)

    Fling (social network)

    Fling was a social media app available for IOS and Android. It was founded in 2014 by Marco Nardone and was taken offline in August 2016. == Overview == In 2012, Marco Nardone founded the startup Unii and launched Unii.com, a social network intended for students in the UK. While working on this service, Nardone had the idea for a messaging service where pictures could be sent to strangers in January 2014. The app Fling was then developed and released between March and July 2014. After a month, it already had 375,000 downloads and 180,000 active users on iOS. Users were able to take pictures inside the app and send them to 50 random people all over the world. The recipient could then choose to answer via chat or reply by sending a picture themselves. The app was used by many users as a medium to exchange sexually explicit pictures and for sexting with strangers. This led to the app being removed from the App Store in June 2015. In the 19 days that followed, flings developers rewrote the App almost completely from scratch, working around the clock. The feature to message random strangers was removed, and the app was readmitted into the App Store as a messenger App resembling Snapchat. But the redesigned Application did not have the success of its predecessor. The funding ran out and the parent company Unii went bankrupt. The company was not able to pay their content moderation team anymore, leading to a new surge of pornographic content on the App. Shortly after that, the Social Network was taken offline in August 2016. It has been inactive since. During the 2 years Fling was online, $21 million was raised from investors while generating no revenue at all. Of this $21 million (£16.5m), £5 million came from Nardone's father. == Allegations against CEO == Former employees made multiple allegations against Marco Nardone, the Founder and CEO of Unii and Fling. According to these claims, he behaved erratic and abusive, throwing "things across the office". He hired his girlfriend as the head of human resources to handle issues between him and his staff. Employees who left the company often had "some part of their pay held back". According to the reports, he also spent the money raised from investors irresponsibly, having no clear concept of a budget. Some of that money was used on expensive restaurants in London, a luxurious office for CEO Nardone and advertisements for Fling on Twitter and Facebook. Nardone also spent time partying in Ibiza with two employees, while the developer team in London frantically tried to get Fling back online after it being removed from the App Store. In December 2017 he pleaded guilty to assaulting his girlfriend at a domestic violence court.

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  • NASA AI Assisted-Air Quality Monitoring Project

    NASA AI Assisted-Air Quality Monitoring Project

    The NASA Expert-System Ion Trap Mass Spectrometer (ES-ITMS) Project was a public-private partnership to develop an artificial intelligence assisted, air quality monitoring system and was qualified for use on the Space Shuttle. The partnership was also the first cost and intellectual property shared public-partnership implemented by NASA, which used the commercial Research and Development Limited Partnership (RDLP) model that had been adopted by the Reagan Administration for Department of Defense semiconductor development, and recommended for use by NASA for space commercialization. The project partners included NASA, the University of Florida and Finnigan MAT Corporation, was organized and administered by the NASA Joint Enterprise Institute (subsequently NASA Joint Sponsored Program) and ran from 1988 through 1990. The partnership concluded final testing in 1991, generating four patents, expert system software and application protocol reports. The system was space qualified for use on the Shuttle and elements of the ES-ITMS system were integrated into the product Improvements for Finnigan MAT corporation. The success of the partnership lead NASA to create a pilot program to develop partnership business models as an ongoing management practice. == Purpose and objectives == The need to monitor air quality in confined spaces represented an increasing challenge for NASA's planned space missions and private sector facility managers facing the increased scrutiny of possible air contaminants. Up to the early 1980's, air quality monitors generally required large spaces and human technicians to interpret readings. This created a need for miniaturized air quality monitors that could generate reliable and accurate analytic results without on-site technician presence. NASA initiated projects to develop..."mobile and/or portable mass spectrometers" that evaluated the "tradeoff between instrumentation capabilities and space, weight and power considerations." NASA selected a "commercial ITMS instrument capable of generating electron ionization, chemical ionization and mass spectrometry data", to develop a linked expert system to accomplish analysis without human intervention. The commercial instrumentation was from Finnigan MAT corporation while the scientific expertise to support expert system development was available at the University of Florida. The project managers at NASA Ames created a single, integrated project using the RDLP model with objectives to: Develop AI/expert system software for instrument control (NASA's role) Expand sensitivity, selectivity and speed of the spectrometer (Univ Florida role) Expand the spectrometer analytic capability and automate the screening (Finnigan role) == Membership == The partnership included seven specialists from five member organizations: Federal Government National Aeronautics and Space Administration (NASA) NASA Ames Research Center (ARC) NASA Kennedy Space Center (KSC) Commercial Finnigan MAT Corporation (Thermo-Fisher Scientific) TGS Technology, Inc. Research Management University of Florida == Organization, management and administration == The technical project was organized into two development teams, one located in at the NASA Ames Research Center covering expert systems and analytic capabilities and one in Florida covering improved sensitivity and testing. The partnership management and administration was provided by a non-profit, partnership support organization: the Joint Enterprise Institute operating through San Francisco State University Foundation (SFSUF) with a NASA employee liaison, Syed Shariq. == Public-private partnership == The partnership structure was as a prototype test of a pilot NASA program to develop public-private partnership business models. The pilot program was known as the NASA Joint Sponsored Research Program (JSRP), which operated as the NASA Joint Enterprise Institute between 1988 and 1991. The partnership was the first public-private, research and development partnership implemented by NASA in response to national policy shifts to increase technology transfer and space commercialization. The partnership structure included a two year technology development and testing plan that cost $610,000, of which NASA funded $310,000, Finnigan $175,000 and the University of Florida $95,000. == Results and commercialization == The project generated patents (4), software (2) and application protocol reports (8). NASA gained use of the patents and jointly development software while Finnigan received commercial utilization rights. The results were commercialized within eighteen months of project completion. == Recognition == NASA recognized the project as a space qualified instrument. Its achievements were reported to the NASA Administrator, directly leading to establishment of the agency-wide Joint Sponsored Research Program.

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  • 2024–present global memory supply shortage

    2024–present global memory supply shortage

    A global computer memory supply shortage started in 2024 due to supply constraints and rapid price escalation in the semiconductor memory market, particularly affecting DRAM and NAND flash memory. This shortage is sometimes labelled by tech media outlets as "RAMmageddon" or the "RAMpocalypse". Unlike the 2020–2023 global chip shortage, which stemmed primarily from pandemic-related supply chain disruptions from COVID-19, this shortage is driven by a structural reallocation of manufacturing capacity toward high-margin products for artificial intelligence infrastructure, creating scarcity of computer memory in consumer and enterprise PC markets. According to a 2026 Kearney's PERLab analysis, the shortage is expected to last at least until 2030, with CEOs agreeing with the timelines. == Background == Following a severe market downturn in 2022–2023, major memory manufacturers—Samsung Electronics, SK Hynix, and Micron Technology—implemented strategic production cuts to stabilize pricing. By mid-2024, the rapid expansion of generative AI services triggered unprecedented demand for specialized memory products, particularly High Bandwidth Memory (HBM) used in AI accelerators and data center GPUs. Specialized components of semiconductor technology are also experiencing supply constraints due to high demand in AI application. For example, glass cloth, a high-performance glass fiber substrate used for power efficient high speed data transfer and a crucial component of semiconductor manufacturing, is experiencing a supply crisis. Nitto Boseki, a Japanese firm having overwhelming monopoly in its production, is not able to meet increased demands, making chip-makers such as Qualcomm, Apple, Nvidia and AMD compete for securing supply. There are also reports of smaller electronics companies struggling to find suppliers for components such as NAND flash. Memory suppliers are adapting to increased demands and market unpredictability by requiring prepayment or shorter time-frame of payment, which makes it more difficult for smaller firms to acquire capital to survive. By 2026, due to steadily increased demand on resources, CPUs are also experiencing shortage issues due to low fabrication capacity, prioritisation of server CPUs, and increased demand, with CPU prices also being forecast to increase by as much as 15%. The demand on memory has also increased strain on other electronic components such as hard disk devices, with reports such as Western Digital's hard disk supply for 2026 being booked for enterprise applications before February 2026. A 2024 McKinsey analysis projected that global demand for AI-ready data center capacity would grow at approximately 33% annually through 2030, with AI workloads consuming roughly 70% of total data center capacity by the decade's end. In addition, according to Kearney's State of Semiconductor 2025 Report, executives were already expecting a shortage in the <8nm wafer size with memory chips being mentioned as an acute source of concern. Multiple companies mentioned being prepared for it through long-term agreements with RAM suppliers or amassing additional inventory. On 24 March 2026, Google announced TurboQuant, a memory compression technology focused on large language models (LLM) and vector search engines, which it claimed achieves 6x lower memory consumption in tested local LLMs and 8x performance enhancement in tests running on H100 accelerators. The technology is also a drop in enhancement for existing inference pipeline. Amid speculation about memory demand trends, memory manufacturers, SanDisk, Micron, Western Digital and Seagate, among other companies involved in memory manufacture experienced stock price declines. Prices of memory kits also reduced in the following months, although still at inflated prices. == Causes == === HBM production displacement === HBM manufacturing requires significantly more wafer capacity per bit than standard DRAM modules. Industry sources reported that as manufacturers allocated increasing wafer capacity to HBM production to meet contracts with AI infrastructure providers, the supply of conventional DDR4 and DDR5 modules for consumer PCs and smartphones contracted sharply. By September 2025, Samsung Electronics had reportedly expanded its 1c DRAM capacity to target 60,000 wafers per month specifically for HBM4 production, further diverting resources from consumer memory lines. === Geopolitical and trade barriers === The supply chain was further constrained by escalating trade tensions between the United States and China. Throughout 2025, fears of U.S. regulatory backlash and new tariff structures led major manufacturers like Samsung and SK Hynix to halt sales of older semiconductor manufacturing equipment to Chinese entities, effectively capping production capacity in the region. Additionally, proposed tariff policies by the U.S. administration in late 2025 prompted supply chain realignments, with Apple reportedly accelerating plans to source all U.S.-bound iPhones from India to avoid potential levies. === NAND flash capacity constraints === In the NAND flash segment, manufacturers prioritized higher-margin enterprise SSDs for data center applications while phasing out older process nodes more rapidly than anticipated. In November 2025, contract prices for NAND wafers increased by more than 60% month-over-month for certain product categories, with 512GB TLC experiencing the steepest rise as legacy manufacturing capacity was retired. == Impact on industry and consumers == === Manufacturer responses === Major PC manufacturers responded to component cost increases with significant price adjustments and supply chain strategies. Dell Technologies Chief Operating Officer Jeff Clarke stated during a November 2025 analyst call that the company had "never witnessed costs escalating at the current pace," describing tighter availability across DRAM, hard drives, and NAND flash memory. Analysts at Morgan Stanley downgraded Dell Technologies stock from "Overweight" to "Underweight" in late 2025, citing the company's heavy exposure to rising server memory costs. The firm warned that skyrocketing memory prices could significantly erode margins for server and PC OEMs. Conversely, Apple Inc. was reportedly less affected than its competitors, having secured long-term supply agreements for DRAM through the first quarter of 2026. Lenovo Chief Financial Officer Winston Cheng described the cost surge as "unprecedented" and disclosed that the company's memory inventories were approximately 50% above normal levels in anticipation of further price increases. === Consumer electronics sector === The shortage particularly affected smartphone manufacturers and other consumer electronics producers. DRAM prices reportedly rose by 172% throughout 2025, leading manufacturers like Samsung to halt new orders for DDR5 modules to reassess pricing structures and Micron to exit its 'Crucial' brand of consumer products. In Tokyo's Akihabara electronics district, retailers began limiting purchases of memory products to prevent hoarding, with prices for popular DDR5 memory modules more than doubling in some cases. Despite the broad trend of rising hardware costs, some companies engaged in aggressive pricing strategies to maintain market share; for example, Sony reduced the price of the PlayStation 5 by $100 for Black Friday 2025, potentially absorbing increased component costs to stimulate software ecosystem growth. Due to memory prices more than doubling in a single quarter, HP revealed in its Q1 2026 earnings call that memory costs account for 35% of PC build materials up from 15-18% previous quarter. Despite showing strong Q1 2026 earning driven by Windows 11 upgrade cycle and AI PC adoption, HP warned investors of low operating margins and up to double digit percentage decline for coming quarter. Trendforce, an IT analytics company, updated its forecast from 1.7% year-over-year growth in PC market to 2.6% year-over-year decline for 2026, amid backdrop of steadily increasing prices and supply crisis. Research and analytics firms, Gartner and IDC expect worldwide PC market to decline 10-11% and smartphone market to decline 8-9% in 2026. Gartner also projects that rising memory prices will make low-margin entry level laptops under 500 USD financially unviable in two years. The RAM shortage has delayed the release of Valve's second Steam Machine due to increased memory prices. The device was originally set to launch in early 2026. === AI infrastructure competition === Technology companies including Google, Amazon, Microsoft, and Meta Platforms placed open-ended orders with memory suppliers, indicating they would accept as much supply as available regardless of cost, according to Reuters sources. The limited supply of AI chips has been cited as a reason for the slow down in compute growth. In October 2025, OpenAI formally announced a strategic partnership using letters of intent with Samsung Electronics and SK Hynix

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  • Artificial intelligence of things

    Artificial intelligence of things

    Artificial Intelligence of Things (AIoT) is the combination of artificial intelligence (AI) technologies with the Internet of things (IoT) infrastructure to create systems capable of sensing, learning, and acting on data without continuous human intervention. While IoT focuses on connectivity and sensor data collection, AI enables IoT devices to analyse data in real time and produce actionable outputs, including automated decisions at the edge. == Applications == === Manufacturing and predictive maintenance === Manufacturing accounts for the largest share of AIoT adoption by industry vertical. A common application is predictive maintenance, where sensors measuring vibration, temperature, current draw, and acoustic emissions feed machine learning models trained to detect signatures that precede equipment failure. These systems can flag developing faults weeks or months in advance, and in more advanced deployments can autonomously adjust machine parameters such as motor speed or cooling cycles to delay or prevent failure. === Other industries === In healthcare, AIoT enables remote patient monitoring through wearable devices that collect vital signs and apply AI models to detect anomalies or predict deterioration. In logistics, GPS and telematics sensors combined with AI models support real-time route optimisation, vehicle maintenance prediction, and fuel cost forecasting. Smart building systems use occupancy, temperature, and energy sensors with AI to dynamically adjust HVAC and lighting, reducing energy consumption. == Architecture == AIoT systems typically operate across three layers: a device layer of sensors and actuators that collect data, a connectivity layer that transmits data via protocols such as MQTT or HTTP, and a compute layer where AI models process the data either in the cloud or at the edge. The trend toward edge-based processing, where inference runs on low-cost processors near the data source rather than in a centralised cloud, has accelerated as hardware costs have fallen and applications increasingly require sub-second response times. == Market == Market sizing estimates for AIoT vary significantly depending on scope and definition. Fortune Business Insights valued the AIoT market at USD 35.65 billion in 2023, projecting growth to USD 253.86 billion by 2030 at a compound annual growth rate of 32.4%. Grand View Research estimated the broader market at USD 171.4 billion in 2024 with a CAGR of 31.7% through 2030, reflecting a wider definition that includes AI-integrated hardware components. North America accounted for approximately 40% of global market share in 2024, with the Asia-Pacific region projected as the fastest-growing market.

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  • Source-code editor

    Source-code editor

    A source-code editor is a text editor program designed specifically for editing the source code of computer programs. It includes basic functionality such as syntax highlighting, and sometimes debugging. It may be a standalone application or it may be built into an integrated development environment (IDE). == Features == Source-code editors have features specifically designed to simplify and speed up typing of source code, such as syntax highlighting(syntax error highlighting), auto indentation, autocomplete and brace matching functionality. These editors may also provide a convenient way to run a compiler, interpreter, debugger, or other program relevant for the software-development process. While many text editors like Notepad can be used to edit source code, if they do not enhance, automate or ease the editing of code, they are not defined as source-code editors. Structure editors are a different form of a source-code editor, where instead of editing raw text, one manipulates the code's structure, generally the abstract syntax tree. In this case features such as syntax highlighting, validation, and code formatting are easily and efficiently implemented from the concrete syntax tree or abstract syntax tree, but editing is often more rigid than free-form text. Structure editors also require extensive support for each language, and thus are harder to extend to new languages than text editors, where basic support only requires supporting syntax highlighting or indentation. For this reason, strict structure editors are not popular for source code editing, though some IDEs provide similar functionality. A source-code editor can check syntax dynamically while code is being entered and immediately warn of syntax problems, as well as suggest code autocomplete snippets. A few source-code editors compress source code, typically converting common keywords into single-byte tokens, removing unnecessary whitespace, and converting numbers to a binary form. Such tokenizing editors later uncompress the source code when viewing it, possibly prettyprinting it with consistent capitalization and spacing. A few source-code editors do both. The Language Server Protocol, first used in Microsoft's Visual Studio Code, allows for source code editors to implement an LSP client that can read syntax information about any language with a LSP server. This allows for source code editors to easily support more languages with syntax highlighting, refactoring, and reference finding. Many source code editors such as Neovim and Brackets have added a built-in LSP client while other editors such as Emacs, Vim, and Sublime Text have support for an LSP Client via a separate plug-in. == History == In 1985, Mike Cowlishaw of IBM created LEXX while seconded to the Oxford University Press. LEXX used live parsing and used color and fonts for syntax highlighting. IBM's LPEX (Live Parsing Extensible Editor) was based on LEXX and ran on VM/CMS, OS/2, OS/400, Windows, and Java Although the initial public release of vim was in 1991, the syntax highlighting feature was not introduced until version 5.0 in 1998. On November 1, 2015, the first version of NeoVim was released. In 2003, Notepad++, a source code editor for Windows, was released by Don Ho. The intention was to create an alternative to the java-based source code editor, JEXT In 2015, Microsoft released Visual Studio Code as a lightweight and cross-platform alternative to their Visual Studio IDE. The following year, Visual Studio Code became the Microsoft product using the Language Server Protocol. This code editor quickly gained popularity and emerged as the most widely used source code editor. == Comparison with IDEs == A source-code editor is one component of a Integrated Development Environment. In contrast to a standalone source-code editor, an IDE typically also includes several tools which enhance the software development process. Such tools include syntax highlighting, code autocomplete suggestions, version control, automatic formatting, integrated runtime environments, debugger, and build tools. Standalone source code editors are preferred over IDEs by some developers when they believe the IDEs are bloated with features they do not need. == Notable examples == == Controversy == Many source-code editors and IDEs have been involved in ongoing user arguments, sometimes referred to jovially as "holy wars" by the programming community. Notable examples include vi vs. Emacs and Eclipse vs. NetBeans. These arguments have formed a significant part of internet culture and they often start whenever either editor is mentioned anywhere.

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  • Bayesian programming

    Bayesian programming

    Bayesian programming is a formalism and a methodology for having a technique to specify probabilistic models and solve problems when less than the necessary information is available. Edwin T. Jaynes proposed that probability could be considered as an alternative and an extension of logic for rational reasoning with incomplete and uncertain information. In his founding book Probability Theory: The Logic of Science he developed this theory and proposed what he called "the robot," which was not a physical device, but an inference engine to automate probabilistic reasoning—a kind of Prolog for probability instead of logic. Bayesian programming is a formal and concrete implementation of this "robot". Bayesian programming may also be seen as an algebraic formalism to specify graphical models such as, for instance, Bayesian networks, dynamic Bayesian networks, Kalman filters or hidden Markov models. Indeed, Bayesian programming is more general than Bayesian networks and has a power of expression equivalent to probabilistic factor graphs. == Formalism == A Bayesian program is a means of specifying a family of probability distributions. The constituent elements of a Bayesian program are presented below: Program { Description { Specification ( π ) { Variables Decomposition Forms Identification (based on δ ) Question {\displaystyle {\text{Program}}{\begin{cases}{\text{Description}}{\begin{cases}{\text{Specification}}(\pi ){\begin{cases}{\text{Variables}}\\{\text{Decomposition}}\\{\text{Forms}}\\\end{cases}}\\{\text{Identification (based on }}\delta )\end{cases}}\\{\text{Question}}\end{cases}}} A program is constructed from a description and a question. A description is constructed using some specification ( π {\displaystyle \pi } ) as given by the programmer and an identification or learning process for the parameters not completely specified by the specification, using a data set ( δ {\displaystyle \delta } ). A specification is constructed from a set of pertinent variables, a decomposition and a set of forms. Forms are either parametric forms or questions to other Bayesian programs. A question specifies which probability distribution has to be computed. === Description === The purpose of a description is to specify an effective method of computing a joint probability distribution on a set of variables { X 1 , X 2 , ⋯ , X N } {\displaystyle \left\{X_{1},X_{2},\cdots ,X_{N}\right\}} given a set of experimental data δ {\displaystyle \delta } and some specification π {\displaystyle \pi } . This joint distribution is denoted as: P ( X 1 ∧ X 2 ∧ ⋯ ∧ X N ∣ δ ∧ π ) {\displaystyle P\left(X_{1}\wedge X_{2}\wedge \cdots \wedge X_{N}\mid \delta \wedge \pi \right)} . To specify preliminary knowledge π {\displaystyle \pi } , the programmer must undertake the following: Define the set of relevant variables { X 1 , X 2 , ⋯ , X N } {\displaystyle \left\{X_{1},X_{2},\cdots ,X_{N}\right\}} on which the joint distribution is defined. Decompose the joint distribution (break it into relevant independent or conditional probabilities). Define the forms of each of the distributions (e.g., for each variable, one of the list of probability distributions). ==== Decomposition ==== Given a partition of { X 1 , X 2 , … , X N } {\displaystyle \left\{X_{1},X_{2},\ldots ,X_{N}\right\}} containing K {\displaystyle K} subsets, K {\displaystyle K} variables are defined L 1 , ⋯ , L K {\displaystyle L_{1},\cdots ,L_{K}} , each corresponding to one of these subsets. Each variable L k {\displaystyle L_{k}} is obtained as the conjunction of the variables { X k 1 , X k 2 , ⋯ } {\displaystyle \left\{X_{k_{1}},X_{k_{2}},\cdots \right\}} belonging to the k t h {\displaystyle k^{th}} subset. Recursive application of Bayes' theorem leads to: P ( X 1 ∧ X 2 ∧ ⋯ ∧ X N ∣ δ ∧ π ) = P ( L 1 ∧ ⋯ ∧ L K ∣ δ ∧ π ) = P ( L 1 ∣ δ ∧ π ) × P ( L 2 ∣ L 1 ∧ δ ∧ π ) × ⋯ × P ( L K ∣ L K − 1 ∧ ⋯ ∧ L 1 ∧ δ ∧ π ) {\displaystyle {\begin{aligned}&P\left(X_{1}\wedge X_{2}\wedge \cdots \wedge X_{N}\mid \delta \wedge \pi \right)\\={}&P\left(L_{1}\wedge \cdots \wedge L_{K}\mid \delta \wedge \pi \right)\\={}&P\left(L_{1}\mid \delta \wedge \pi \right)\times P\left(L_{2}\mid L_{1}\wedge \delta \wedge \pi \right)\times \cdots \times P\left(L_{K}\mid L_{K-1}\wedge \cdots \wedge L_{1}\wedge \delta \wedge \pi \right)\end{aligned}}} Conditional independence hypotheses then allow further simplifications. A conditional independence hypothesis for variable L k {\displaystyle L_{k}} is defined by choosing some variable X n {\displaystyle X_{n}} among the variables appearing in the conjunction L k − 1 ∧ ⋯ ∧ L 2 ∧ L 1 {\displaystyle L_{k-1}\wedge \cdots \wedge L_{2}\wedge L_{1}} , labelling R k {\displaystyle R_{k}} as the conjunction of these chosen variables and setting: P ( L k ∣ L k − 1 ∧ ⋯ ∧ L 1 ∧ δ ∧ π ) = P ( L k ∣ R k ∧ δ ∧ π ) {\displaystyle P\left(L_{k}\mid L_{k-1}\wedge \cdots \wedge L_{1}\wedge \delta \wedge \pi \right)=P\left(L_{k}\mid R_{k}\wedge \delta \wedge \pi \right)} We then obtain: P ( X 1 ∧ X 2 ∧ ⋯ ∧ X N ∣ δ ∧ π ) = P ( L 1 ∣ δ ∧ π ) × P ( L 2 ∣ R 2 ∧ δ ∧ π ) × ⋯ × P ( L K ∣ R K ∧ δ ∧ π ) {\displaystyle {\begin{aligned}&P\left(X_{1}\wedge X_{2}\wedge \cdots \wedge X_{N}\mid \delta \wedge \pi \right)\\={}&P\left(L_{1}\mid \delta \wedge \pi \right)\times P\left(L_{2}\mid R_{2}\wedge \delta \wedge \pi \right)\times \cdots \times P\left(L_{K}\mid R_{K}\wedge \delta \wedge \pi \right)\end{aligned}}} Such a simplification of the joint distribution as a product of simpler distributions is called a decomposition, derived using the chain rule. This ensures that each variable appears at the most once on the left of a conditioning bar, which is the necessary and sufficient condition to write mathematically valid decompositions. ==== Forms ==== Each distribution P ( L k ∣ R k ∧ δ ∧ π ) {\displaystyle P\left(L_{k}\mid R_{k}\wedge \delta \wedge \pi \right)} appearing in the product is then associated with either a parametric form (i.e., a function f μ ( L k ) {\displaystyle f_{\mu }\left(L_{k}\right)} ) or a question to another Bayesian program P ( L k ∣ R k ∧ δ ∧ π ) = P ( L ∣ R ∧ δ ^ ∧ π ^ ) {\displaystyle P\left(L_{k}\mid R_{k}\wedge \delta \wedge \pi \right)=P\left(L\mid R\wedge {\widehat {\delta }}\wedge {\widehat {\pi }}\right)} . When it is a form f μ ( L k ) {\displaystyle f_{\mu }\left(L_{k}\right)} , in general, μ {\displaystyle \mu } is a vector of parameters that may depend on R k {\displaystyle R_{k}} or δ {\displaystyle \delta } or both. Learning takes place when some of these parameters are computed using the data set δ {\displaystyle \delta } . An important feature of Bayesian programming is this capacity to use questions to other Bayesian programs as components of the definition of a new Bayesian program. P ( L k ∣ R k ∧ δ ∧ π ) {\displaystyle P\left(L_{k}\mid R_{k}\wedge \delta \wedge \pi \right)} is obtained by some inferences done by another Bayesian program defined by the specifications π ^ {\displaystyle {\widehat {\pi }}} and the data δ ^ {\displaystyle {\widehat {\delta }}} . This is similar to calling a subroutine in classical programming and provides an easy way to build hierarchical models. === Question === Given a description (i.e., P ( X 1 ∧ X 2 ∧ ⋯ ∧ X N ∣ δ ∧ π ) {\displaystyle P\left(X_{1}\wedge X_{2}\wedge \cdots \wedge X_{N}\mid \delta \wedge \pi \right)} ), a question is obtained by partitioning { X 1 , X 2 , ⋯ , X N } {\displaystyle \left\{X_{1},X_{2},\cdots ,X_{N}\right\}} into three sets: the searched variables, the known variables and the free variables. The 3 variables S e a r c h e d {\displaystyle Searched} , K n o w n {\displaystyle Known} and F r e e {\displaystyle Free} are defined as the conjunction of the variables belonging to these sets. A question is defined as the set of distributions: P ( S e a r c h e d ∣ Known ∧ δ ∧ π ) {\displaystyle P\left(Searched\mid {\text{Known}}\wedge \delta \wedge \pi \right)} made of many "instantiated questions" as the cardinal of K n o w n {\displaystyle Known} , each instantiated question being the distribution: P ( Searched ∣ Known ∧ δ ∧ π ) {\displaystyle P\left({\text{Searched}}\mid {\text{Known}}\wedge \delta \wedge \pi \right)} === Inference === Given the joint distribution P ( X 1 ∧ X 2 ∧ ⋯ ∧ X N ∣ δ ∧ π ) {\displaystyle P\left(X_{1}\wedge X_{2}\wedge \cdots \wedge X_{N}\mid \delta \wedge \pi \right)} , it is always possible to compute any possible question using the following general inference: P ( Searched ∣ Known ∧ δ ∧ π ) = ∑ Free [ P ( Searched ∧ Free ∣ Known ∧ δ ∧ π ) ] = ∑ Free [ P ( Searched ∧ Free ∧ Known ∣ δ ∧ π ) ] P ( Known ∣ δ ∧ π ) = ∑ Free [ P ( Searched ∧ Free ∧ Known ∣ δ ∧ π ) ] ∑ Free ∧ Searched [ P ( Searched ∧ Free ∧ Known ∣ δ ∧ π ) ] = 1 Z × ∑ Free [ P ( Searched ∧ Free ∧ Known ∣ δ ∧ π ) ] {\displaystyle {\begin{aligned}&P\left({\text{Searched}}\mid {\text{Known}}\wedge \delta \wedge \pi \right)\\={}&\sum _{\text{Free}}\left[P\left({\text{Searched}}\wedge {\text{Free}}\mid {\text{Known}}\wedge \delta \wedge \

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  • Intelligent agent

    Intelligent agent

    In artificial intelligence, an intelligent agent is an entity that perceives its environment, takes actions autonomously to achieve goals, and may improve its performance through machine learning or by acquiring knowledge. AI textbooks define artificial intelligence as the "study and design of intelligent agents," emphasizing that goal-directed behavior is central to intelligence. A specialized subset of intelligent agents, agentic AI (also known as an AI agent or simply agent), expands this concept by proactively pursuing goals, making decisions, and taking actions over extended periods. Intelligent agents can range from simple to highly complex. A basic thermostat or control system is considered an intelligent agent, as is a human being, or any other system that meets the same criteria—such as a firm, a state, or a biome. Intelligent agents operate based on an objective function, which encapsulates their goals. They are designed to create and execute plans that maximize the expected value of this function upon completion. For example, a reinforcement learning agent has a reward function, which allows programmers to shape its desired behavior. Similarly, an evolutionary algorithm's behavior is guided by a fitness function. Intelligent agents in artificial intelligence are closely related to agents in economics, and versions of the intelligent agent paradigm are studied in cognitive science, ethics, and the philosophy of practical reason, as well as in many interdisciplinary socio-cognitive modeling and computer social simulations. Intelligent agents are often described schematically as abstract functional systems similar to computer programs . To distinguish theoretical models from real-world implementations, abstract descriptions of intelligent agents are called abstract intelligent agents. Intelligent agents are also closely related to software agents—autonomous computer programs that carry out tasks on behalf of users. They are also referred to using a term borrowed from economics: a "rational agent". == Intelligent agents as the foundation of AI == The concept of intelligent agents provides a foundational lens through which to define and understand artificial intelligence. For instance, the influential textbook Artificial Intelligence: A Modern Approach (Russell & Norvig) describes: Agent: Anything that perceives its environment (using sensors) and acts upon it (using actuators). E.g., a robot with cameras and wheels, or a software program that reads data and makes recommendations. Rational Agent: An agent that strives to achieve the best possible outcome based on its knowledge and past experiences. "Best" is defined by a performance measure – a way of evaluating how well the agent is doing. Artificial Intelligence (as a field): The study and creation of these rational agents. Other researchers and definitions build upon this foundation. Padgham & Winikoff emphasize that intelligent agents should react to changes in their environment in a timely way, proactively pursue goals, and be flexible and robust (able to handle unexpected situations). Some also suggest that ideal agents should be "rational" in the economic sense (making optimal choices) and capable of complex reasoning, like having beliefs, desires, and intentions (BDI model). Kaplan and Haenlein offer a similar definition, focusing on a system's ability to understand external data, learn from that data, and use what is learned to achieve goals through flexible adaptation. Defining AI in terms of intelligent agents offers several key advantages: Avoids Philosophical Debates: It sidesteps arguments about whether AI is "truly" intelligent or conscious, like those raised by the Turing test or Searle's Chinese Room. It focuses on behavior and goal achievement, not on replicating human thought. Objective Testing: It provides a clear, scientific way to evaluate AI systems. Researchers can compare different approaches by measuring how well they maximize a specific "goal function" (or objective function). This allows for direct comparison and combination of techniques. Interdisciplinary Communication: It creates a common language for AI researchers to collaborate with other fields like mathematical optimization and economics, which also use concepts like "goals" and "rational agents." == Objective function == An objective function (or goal function) specifies the goals of an intelligent agent. An agent is deemed more intelligent if it consistently selects actions that yield outcomes better aligned with its objective function. In effect, the objective function serves as a measure of success. The objective function may be: Simple: For example, in a game of Go, the objective function might assign a value of 1 for a win and 0 for a loss. Complex: It might require the agent to evaluate and learn from past actions, adapting its behavior based on patterns that have proven effective. The objective function encapsulates all of the goals the agent is designed to achieve. For rational agents, it also incorporates the trade-offs between potentially conflicting goals. For instance, a self-driving car's objective function might balance factors such as safety, speed, and passenger comfort. Different terms are used to describe this concept, depending on the context. These include: Utility function: Often used in economics and decision theory, representing the desirability of a state. Objective function: A general term used in optimization. Loss function: Typically used in machine learning, where the goal is to minimize the loss (error). Reward Function: Used in reinforcement learning. Fitness Function: Used in evolutionary systems. Goals, and therefore the objective function, can be: Explicitly defined: Programmed directly into the agent. Induced: Learned or evolved over time. In reinforcement learning, a "reward function" provides feedback, encouraging desired behaviors and discouraging undesirable ones. The agent learns to maximize its cumulative reward. In evolutionary systems, a "fitness function" determines which agents are more likely to reproduce. This is analogous to natural selection, where organisms evolve to maximize their chances of survival and reproduction. Some AI systems, such as nearest-neighbor, reason by analogy rather than being explicitly goal-driven. However, even these systems can have goals implicitly defined within their training data. Such systems can still be benchmarked by framing the non-goal system as one whose "goal" is to accomplish its narrow classification task. Systems not traditionally considered agents, like knowledge-representation systems, are sometimes included in the paradigm by framing them as agents with a goal of, for example, answering questions accurately. Here, the concept of an "action" is extended to encompass the "act" of providing an answer. As a further extension, mimicry-driven systems can be framed as agents optimizing a "goal function" based on how closely the agent mimics the desired behavior. In generative adversarial networks (GANs) of the 2010s, an "encoder"/"generator" component attempts to mimic and improvise human text composition. The generator tries to maximize a function representing how well it can fool an antagonistic "predictor"/"discriminator" component. While symbolic AI systems often use an explicit goal function, the paradigm also applies to neural networks and evolutionary computing. Reinforcement learning can generate intelligent agents that appear to act in ways intended to maximize a "reward function". Sometimes, instead of setting the reward function directly equal to the desired benchmark evaluation function, machine learning programmers use reward shaping to initially give the machine rewards for incremental progress. Yann LeCun stated in 2018, "Most of the learning algorithms that people have come up with essentially consist of minimizing some objective function." AlphaZero chess had a simple objective function: +1 point for each win, and -1 point for each loss. A self-driving car's objective function would be more complex. Evolutionary computing can evolve intelligent agents that appear to act in ways intended to maximize a "fitness function" influencing how many descendants each agent is allowed to leave. The mathematical formalism of AIXI was proposed as a maximally intelligent agent in this paradigm. However, AIXI is uncomputable. In the real world, an intelligent agent is constrained by finite time and hardware resources, and scientists compete to produce algorithms that achieve progressively higher scores on benchmark tests with existing hardware. == Agent function == An intelligent agent's behavior can be described mathematically by an agent function. This function determines what the agent does based on what it has seen. A percept refers to the agent's sensory inputs at a single point in time. For example, a self-driving car's percepts might include camera images, lidar data, GPS coordinates, and speed r

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  • Personoid

    Personoid

    Personoid is the concept coined by Stanisław Lem, a Polish science-fiction writer, in Non Serviam, from his book A Perfect Vacuum (1971). His personoids are an abstraction of functions of human mind and they live in computers; they do not need any human-like physical body. In cognitive and software modeling, personoid is a research approach to the development of intelligent autonomous agents. In frame of the IPK (Information, Preferences, Knowledge) architecture, it is a framework of abstract intelligent agent with a cognitive and structural intelligence. It can be seen as an essence of high intelligent entities. From the philosophical and systemics perspectives, personoid societies can also be seen as the carriers of a culture. According to N. Gessler, the personoids study can be a base for the research on artificial culture and culture evolution. == Personoids on TV and cinema == Welt am Draht (1973) The Thirteenth Floor (1999)

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  • Database application

    Database application

    A database application is a computer program whose primary purpose is retrieving information from a computerized database. From here, information can be inserted, modified or deleted which is subsequently conveyed back into the database. Early examples of database applications were accounting systems and airline reservations systems, such as SABRE, developed starting in 1957. A characteristic of modern database applications is that they facilitate simultaneous updates and queries from multiple users. Systems in the 1970s might have accomplished this by having each user in front of a 3270 terminal to a mainframe computer. By the mid-1980s it was becoming more common to give each user a personal computer and have a program running on that PC that is connected to a database server. Information would be pulled from the database, transmitted over a network, and then arranged, graphed, or otherwise formatted by the program running on the PC. Starting in the mid-1990s it became more common to build database applications with a Web interface. Rather than develop custom software to run on a user's PC, the user would use the same Web browser program for every application. A database application with a Web interface had the advantage that it could be used on devices of different sizes, with different hardware, and with different operating systems. Examples of early database applications with Web interfaces include amazon.com, which used the Oracle relational database management system, the photo.net online community, whose implementation on top of Oracle was described in the book Database-Backed Web Sites (Ziff-Davis Press; May 1997), and eBay, also running Oracle. Electronic medical records are referred to on emrexperts.com, in December 2010, as "a software database application". A 2005 O'Reilly book uses the term in its title: Database Applications and the Web. Some of the most complex database applications remain accounting systems, such as SAP, which may contain thousands of tables in only a single module. Many of today's most widely used computer systems are database applications, for example, Facebook, which was built on top of MySQL. The etymology of the phrase "database application" comes from the practice of dividing computer software into systems programs, such as the operating system, compilers, the file system, and tools such as the database management system, and application programs, such as a payroll check processor. On a standard PC running Microsoft Windows, for example, the Windows operating system contains all of the systems programs while games, word processors, spreadsheet programs, photo editing programs, etc. would be application programs. As "application" is short for "application program", "database application" is short for "database application program". Not every program that uses a database would typically be considered a "database application". For example, many physics experiments, e.g., the Large Hadron Collider, generate massive data sets that programs subsequently analyze. The data sets constitute a "database", though they are not typically managed with a standard relational database management system. The computer programs that analyze the data are primarily developed to answer hypotheses, not to put information back into the database and therefore the overall program would not be called a "database application". == Examples of database applications == Amazon Student Data CNN eBay Facebook Fandango Filemaker (Mac OS) LibreOffice Base Microsoft Access Oracle relational database SAP (Systems, Applications & Products in Data Processing) Ticketmaster Wikipedia Yelp YouTube Google MySQL

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  • Automated Mathematician

    Automated Mathematician

    The Automated Mathematician (AM) is one of the earliest successful discovery systems. It was created by Douglas Lenat in Lisp, and in 1977 led to Lenat being awarded the IJCAI Computers and Thought Award. AM worked by generating and modifying short Lisp programs which were then interpreted as defining various mathematical concepts; for example, a program that tested equality between the length of two lists was considered to represent the concept of numerical equality, while a program that produced a list whose length was the product of the lengths of two other lists was interpreted as representing the concept of multiplication. The system had elaborate heuristics for choosing which programs to extend and modify, based on the experiences of working mathematicians in solving mathematical problems. == Controversy == Lenat claimed that the system was composed of hundreds of data structures called "concepts", together with hundreds of "heuristic rules" and a simple flow of control: "AM repeatedly selects the top task from the agenda and tries to carry it out. This is the whole control structure!" Yet the heuristic rules were not always represented as separate data structures; some had to be intertwined with the control flow logic. Some rules had preconditions that depended on the history, or otherwise could not be represented in the framework of the explicit rules. What's more, the published versions of the rules often involve vague terms that are not defined further, such as "If two expressions are structurally similar, ..." (Rule 218) or "... replace the value obtained by some other (very similar) value..." (Rule 129). Another source of information is the user, via Rule 2: "If the user has recently referred to X, then boost the priority of any tasks involving X." Thus, it appears quite possible that much of the real discovery work is buried in unexplained procedures. Lenat claimed that the system had rediscovered both Goldbach's conjecture and the fundamental theorem of arithmetic. Later critics accused Lenat of over-interpreting the output of AM. In his paper Why AM and Eurisko appear to work, Lenat conceded that any system that generated enough short Lisp programs would generate ones that could be interpreted by an external observer as representing equally sophisticated mathematical concepts. However, he argued that this property was in itself interesting—and that a promising direction for further research would be to look for other languages in which short random strings were likely to be useful. == Successor == This intuition was the basis of AM's successor Eurisko, which attempted to generalize the search for mathematical concepts to the search for useful heuristics.

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  • EM algorithm and GMM model

    EM algorithm and GMM model

    In statistics, EM (expectation maximization) algorithm handles latent variables, while GMM is the Gaussian mixture model. == Background == In the picture below, are shown the red blood cell hemoglobin concentration and the red blood cell volume data of two groups of people, the Anemia group and the control group (i.e. the group of people without Anemia). As expected, people with Anemia have lower red blood cell volume and lower red blood cell hemoglobin concentration than those without Anemia. x {\displaystyle x} is a random vector such as x := ( red blood cell volume , red blood cell hemoglobin concentration ) {\displaystyle x:={\big (}{\text{red blood cell volume}},{\text{red blood cell hemoglobin concentration}}{\big )}} , and from medical studies it is known that x {\displaystyle x} are normally distributed in each group, i.e. x ∼ N ( μ , Σ ) {\displaystyle x\sim {\mathcal {N}}(\mu ,\Sigma )} . z {\displaystyle z} is denoted as the group where x {\displaystyle x} belongs, with z i = 0 {\displaystyle z_{i}=0} when x i {\displaystyle x_{i}} belongs to the Anemia group and z i = 1 {\displaystyle z_{i}=1} when x i {\displaystyle x_{i}} belongs to the control group. Also z ∼ Categorical ⁡ ( k , ϕ ) {\displaystyle z\sim \operatorname {Categorical} (k,\phi )} where k = 2 {\displaystyle k=2} , ϕ j ≥ 0 , {\displaystyle \phi _{j}\geq 0,} and ∑ j = 1 k ϕ j = 1 {\displaystyle \sum _{j=1}^{k}\phi _{j}=1} . See Categorical distribution. The following procedure can be used to estimate ϕ , μ , Σ {\displaystyle \phi ,\mu ,\Sigma } . A maximum likelihood estimation can be applied: ℓ ( ϕ , μ , Σ ) = ∑ i = 1 m log ⁡ ( p ( x ( i ) ; ϕ , μ , Σ ) ) = ∑ i = 1 m log ⁡ ∑ z ( i ) = 1 k p ( x ( i ) ∣ z ( i ) ; μ , Σ ) p ( z ( i ) ; ϕ ) {\displaystyle \ell (\phi ,\mu ,\Sigma )=\sum _{i=1}^{m}\log(p(x^{(i)};\phi ,\mu ,\Sigma ))=\sum _{i=1}^{m}\log \sum _{z^{(i)}=1}^{k}p\left(x^{(i)}\mid z^{(i)};\mu ,\Sigma \right)p(z^{(i)};\phi )} As the z i {\displaystyle z_{i}} for each x i {\displaystyle x_{i}} are known, the log likelihood function can be simplified as below: ℓ ( ϕ , μ , Σ ) = ∑ i = 1 m log ⁡ p ( x ( i ) ∣ z ( i ) ; μ , Σ ) + log ⁡ p ( z ( i ) ; ϕ ) {\displaystyle \ell (\phi ,\mu ,\Sigma )=\sum _{i=1}^{m}\log p\left(x^{(i)}\mid z^{(i)};\mu ,\Sigma \right)+\log p\left(z^{(i)};\phi \right)} Now the likelihood function can be maximized by making partial derivative over μ , Σ , ϕ {\displaystyle \mu ,\Sigma ,\phi } , obtaining: ϕ j = 1 m ∑ i = 1 m 1 { z ( i ) = j } {\displaystyle \phi _{j}={\frac {1}{m}}\sum _{i=1}^{m}1\{z^{(i)}=j\}} μ j = ∑ i = 1 m 1 { z ( i ) = j } x ( i ) ∑ i = 1 m 1 { z ( i ) = j } {\displaystyle \mu _{j}={\frac {\sum _{i=1}^{m}1\{z^{(i)}=j\}x^{(i)}}{\sum _{i=1}^{m}1\left\{z^{(i)}=j\right\}}}} Σ j = ∑ i = 1 m 1 { z ( i ) = j } ( x ( i ) − μ j ) ( x ( i ) − μ j ) T ∑ i = 1 m 1 { z ( i ) = j } {\displaystyle \Sigma _{j}={\frac {\sum _{i=1}^{m}1\{z^{(i)}=j\}(x^{(i)}-\mu _{j})(x^{(i)}-\mu _{j})^{T}}{\sum _{i=1}^{m}1\{z^{(i)}=j\}}}} If z i {\displaystyle z_{i}} is known, the estimation of the parameters results to be quite simple with maximum likelihood estimation. But if z i {\displaystyle z_{i}} is unknown it is much more complicated. Being z {\displaystyle z} a latent variable (i.e. not observed), with unlabeled scenario, the expectation maximization algorithm is needed to estimate z {\displaystyle z} as well as other parameters. Generally, this problem is set as a GMM since the data in each group is normally distributed. In machine learning, the latent variable z {\displaystyle z} is considered as a latent pattern lying under the data, which the observer is not able to see very directly. x i {\displaystyle x_{i}} is the known data, while ϕ , μ , Σ {\displaystyle \phi ,\mu ,\Sigma } are the parameter of the model. With the EM algorithm, some underlying pattern z {\displaystyle z} in the data x i {\displaystyle x_{i}} can be found, along with the estimation of the parameters. The wide application of this circumstance in machine learning is what makes EM algorithm so important. == EM algorithm in GMM == The EM algorithm consists of two steps: the E-step and the M-step. Firstly, the model parameters and the z ( i ) {\displaystyle z^{(i)}} can be randomly initialized. In the E-step, the algorithm tries to guess the value of z ( i ) {\displaystyle z^{(i)}} based on the parameters, while in the M-step, the algorithm updates the value of the model parameters based on the guess of z ( i ) {\displaystyle z^{(i)}} of the E-step. These two steps are repeated until convergence is reached. The algorithm in GMM is: Repeat until convergence: 1. (E-step) For each i , j {\displaystyle i,j} , set w j ( i ) := p ( z ( i ) = j | x ( i ) ; ϕ , μ , Σ ) {\displaystyle w_{j}^{(i)}:=p\left(z^{(i)}=j|x^{(i)};\phi ,\mu ,\Sigma \right)} 2. (M-step) Update the parameters ϕ j := 1 m ∑ i = 1 m w j ( i ) {\displaystyle \phi _{j}:={\frac {1}{m}}\sum _{i=1}^{m}w_{j}^{(i)}} μ j := ∑ i = 1 m w j ( i ) x ( i ) ∑ i = 1 m w j ( i ) {\displaystyle \mu _{j}:={\frac {\sum _{i=1}^{m}w_{j}^{(i)}x^{(i)}}{\sum _{i=1}^{m}w_{j}^{(i)}}}} Σ j := ∑ i = 1 m w j ( i ) ( x ( i ) − μ j ) ( x ( i ) − μ j ) T ∑ i = 1 m w j ( i ) {\displaystyle \Sigma _{j}:={\frac {\sum _{i=1}^{m}w_{j}^{(i)}\left(x^{(i)}-\mu _{j}\right)\left(x^{(i)}-\mu _{j}\right)^{T}}{\sum _{i=1}^{m}w_{j}^{(i)}}}} With Bayes' rule, the following result is obtained by the E-step: p ( z ( i ) = j | x ( i ) ; ϕ , μ , Σ ) = p ( x ( i ) | z ( i ) = j ; μ , Σ ) p ( z ( i ) = j ; ϕ ) ∑ l = 1 k p ( x ( i ) | z ( i ) = l ; μ , Σ ) p ( z ( i ) = l ; ϕ ) {\displaystyle p\left(z^{(i)}=j|x^{(i)};\phi ,\mu ,\Sigma \right)={\frac {p\left(x^{(i)}|z^{(i)}=j;\mu ,\Sigma \right)p\left(z^{(i)}=j;\phi \right)}{\sum _{l=1}^{k}p\left(x^{(i)}|z^{(i)}=l;\mu ,\Sigma \right)p\left(z^{(i)}=l;\phi \right)}}} According to GMM setting, these following formulas are obtained: p ( x ( i ) | z ( i ) = j ; μ , Σ ) = 1 ( 2 π ) n / 2 | Σ j | 1 / 2 exp ⁡ ( − 1 2 ( x ( i ) − μ j ) T Σ j − 1 ( x ( i ) − μ j ) ) {\displaystyle p\left(x^{(i)}|z^{(i)}=j;\mu ,\Sigma \right)={\frac {1}{(2\pi )^{n/2}\left|\Sigma _{j}\right|^{1/2}}}\exp \left(-{\frac {1}{2}}\left(x^{(i)}-\mu _{j}\right)^{T}\Sigma _{j}^{-1}\left(x^{(i)}-\mu _{j}\right)\right)} p ( z ( i ) = j ; ϕ ) = ϕ j {\displaystyle p\left(z^{(i)}=j;\phi \right)=\phi _{j}} In this way, a switch between the E-step and the M-step is possible, according to the randomly initialized parameters.

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