AI Analytics Healthcare

AI Analytics Healthcare — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

• 

  Vulnerability assessment (computing)

  Vulnerability assessment is a process of defining, identifying and classifying the security holes in information technology systems. An attacker can exploit a vulnerability to violate the security of a system. Some known vulnerabilities are Authentication Vulnerability, Authorization Vulnerability and Input Validation Vulnerability. == Purpose == Before deploying a system, it first must go through from a series of vulnerability assessments that will ensure that the build system is secure from all the known security risks. When a new vulnerability is discovered, the system administrator can again perform an assessment, discover which modules are vulnerable, and start the patch process. After the fixes are in place, another assessment can be run to verify that the vulnerabilities were actually resolved. This cycle of assess, patch, and re-assess has become the standard method for many organizations to manage their security issues. The primary purpose of the assessment is to find the vulnerabilities in the system, but the assessment report conveys to stakeholders that the system is secured from these vulnerabilities. If an intruder gained access to a network consisting of vulnerable Web servers, it is safe to assume that he gained access to those systems as well. Because of assessment report, the security administrator will be able to determine how intrusion occurred, identify compromised assets and take appropriate security measures to prevent critical damage to the system. == Assessment types == Depending on the system a vulnerability assessment can have many types and level. === Host assessment === A host assessment looks for system-level vulnerabilities such as insecure file permissions, application level bugs, backdoor and Trojan horse installations. It requires specialized tools for the operating system and software packages being used, in addition to administrative access to each system that should be tested. Host assessment is often very costly in term of time, and thus is only used in the assessment of critical systems. Tools like COPS and Tiger are popular in host assessment. === Network assessment === In a network assessment one assess the network for known vulnerabilities. It locates all systems on a network, determines what network services are in use, and then analyzes those services for potential vulnerabilities. This process does not require any configuration changes on the systems being assessed. Unlike host assessment, network assessment requires little computational cost and effort. == Vulnerability assessment vs penetration testing == Vulnerability assessment and penetration testing are two different testing methods. They are differentiated on the basis of certain specific parameters. == Regulatory requirements == Vulnerability assessments are mandated or strongly recommended by several regulatory frameworks. In the United States healthcare sector, the Health Insurance Portability and Accountability Act (HIPAA) Security Rule requires covered entities to conduct periodic evaluations of their security posture, and a December 2024 Notice of Proposed Rulemaking would explicitly require vulnerability scanning at least every six months for systems containing electronic protected health information. The Payment Card Industry Data Security Standard (PCI DSS) requires quarterly vulnerability scans for organizations that process credit card transactions, and the NIST Cybersecurity Framework includes vulnerability assessment as a core component of its Identify function.

  Read more →
• 

  Taxonomic database

  A taxonomic database is a database created to hold information on biological taxa – for example groups of organisms organized by species name or other taxonomic identifier – for efficient data management and information retrieval. Taxonomic databases are routinely used for the automated construction of biological checklists such as floras and faunas, both for print publication and online; to underpin the operation of web-based species information systems; as a part of biological collection management (for example in museums and herbaria); as well as providing, in some cases, the taxon management component of broader science or biology information systems. They are also a fundamental contribution to the discipline of biodiversity informatics. == Goals == Taxonomic databases digitize scientific biodiversity data and provide access to taxonomic data for research. Taxonomic databases vary in breadth of the groups of taxa and geographical space they seek to include, for example: beetles in a defined region, mammals globally, or all described taxa in the tree of life. A taxonomic database may incorporate organism identifiers (scientific name, author, and – for zoological taxa – year of original publication), synonyms, taxonomic opinions, literature sources or citations, illustrations or photographs, and biological attributes for each taxon (such as geographic distribution, ecology, descriptive information, threatened or vulnerable status, etc.). Some databases, such as the Global Biodiversity Information Facility(GBIF) database and the Barcode of Life Data System, store the DNA barcode of a taxon if one exists (also called the Barcode Index Number (BIN) which may be assigned, for example, by the International Barcode of Life project (iBOL) or UNITE, a database for fungal DNA barcoding). A taxonomic database aims to accurately model the characteristics of interest that are relevant to the organisms which are in scope for the intended coverage and usage of the system. For example, databases of fungi, algae, bryophytes and vascular plants ("higher plants") encode conventions from the International Code of Botanical Nomenclature while their counterparts for animals and most protists encode equivalent rules from the International Code of Zoological Nomenclature. Modelling the relevant taxonomic hierarchy for any taxon is a natural fit with the relational model employed in almost all database systems. Scientific consensus is not reached for all taxon groups, and new species continue to be described; therefore, another goal of taxonomic databases is to aid in resolving conflicts of scientific opinion and unify taxonomy. == History == Possibly the earliest documented management of taxonomic information in computerised form comprised the taxonomic coding system developed by Richard Swartz et al. at the Virginia Institute of Marine Science for the Biota of Chesapeake Bay and described in a published report in 1972. This work led directly or indirectly to other projects with greater profile including the NODC Taxonomic Code system which went through 8 versions before being discontinued in 1996, to be subsumed and transformed into the still current Integrated Taxonomic Information System (ITIS). A number of other taxonomic databases specializing in particular groups of organisms that appeared in the 1970s through to the present jointly contribute to the Species 2000 project, which since 2001 has been partnering with ITIS to produce a combined product, the Catalogue of Life. While the Catalogue of Life currently concentrates on assembling basic name information as a global species checklist, numerous other taxonomic database projects such as Fauna Europaea, the Australian Faunal Directory, and more supply rich ancillary information including descriptions, illustrations, maps, and more. Many taxonomic database projects are currently listed at the TDWG "Biodiversity Information Projects of the World" site. == Issues == The representation of taxonomic information in machine-encodable form raises a number of issues not encountered in other domains, such as variant ways to cite the same species or other taxon name, the same name used for multiple taxa (homonyms), multiple non-current names for the same taxon (synonyms), changes in name and taxon concept definition through time, and more. Non-standardized categories and metadata in taxonomic databases hampers the ability for researchers to analyze the data. One forum that has promoted discussion and possible solutions to these and related problems since 1985 is the Biodiversity Information Standards (TDWG), originally called the Taxonomic Database Working Group. While online databases have great benefits (for example, increased access to taxonomic information), they also have issues such as data integrity risks due to on- and off-line versions and continuous updates, technical access issues due to server or internet outage, and differing capacities for complex queries to extract taxonomic data into lists. As the quantity of information in online taxonomic databases rapidly expands, data aggregation, and the integration and alignment of non-standardized data across databases, is a big challenge in taxonomy and biodiversity informatics.

  Read more →
• 

  Master data management

  Master data management (MDM) is a discipline in which business and information technology collaborate to ensure the uniformity, accuracy, stewardship, semantic consistency, and accountability of the enterprise's official shared master data assets. == Reasons for master data management == Data consistency and accuracy: MDM ensures that the organization's critical data is consistent and accurate across all systems, reducing discrepancies and errors caused by multiple, siloed copies of the same data. Improved decision-making: By providing a single version of the truth (SVOT), MDM enables organizations to deliver the right data to decision makers, allowing them to clearly understand business performance and make informed, data-driven decisions. Operational efficiency: With the consistent and accurate data provided by an MDM, operational processes such as reporting and inventory management can be automated to improve efficiency. Employee learning, onboarding, and customer service also become more efficient, as MDM data facilitates rapid, accurate, and thorough information retrieval, permitting more employee time to be spent on work. Regulatory compliance: MDM tries to help organizations comply with industry standards and regulations by ensuring that master data is accurately recorded, maintained, and audited. However, issues with data quality, classification, and reconciliation may require data transformation. As with other Extract, Transform, Load-based data movements, these processes are expensive and inefficient, reducing return on investment for a project. == Business unit and product line segmentation == As a result of business unit and product line segmentation, the same entity (whether a customer, supplier, or product) will be included in different product lines. This leads to data redundancy and even confusion. For example, a customer takes out a mortgage at a bank. If the marketing and customer service departments have separate databases, advertisements might still be sent to the customer, even though they've already signed up. The two parts of the bank are unaware, and the customer is sent irrelevant communications. Record linkage can associate different records corresponding to the same entity, mitigating this issue. == Mergers and acquisitions == One of the most common problems for master data management is company growth through mergers or acquisitions. Reconciling these separate master data systems can present difficulties, as existing applications have dependencies on the master databases. Ideally, database administrators resolve this problem through deduplication of the master data as part of the merger. Over time, as further mergers and acquisitions occur, the problem can multiply. Data reconciliation processes can become extremely complex or even unreliable. Some organizations end up with 10, 15, or even 100 separate and poorly integrated master databases. This can cause serious problems in customer satisfaction, operational efficiency, decision support, and regulatory compliance. Another problem involves determining the proper degrees of detail and normalization to include in the master data schema. For example, in a federated Human Resources environment, the enterprise software may focus on storing people's data as current status, adding a few fields to identify the date of hire, date of last promotion, etc. However, this simplification can introduce business-impacting errors into dependent systems for planning and forecasting. The stakeholders of such systems may be forced to build a parallel network of new interfaces to track the onboarding of new hires, planned retirements, and divestment, which works against one of the aims of master data management. == People, processes and technology == Master data management is enabled by technology, but is more than the technologies that enable it. An organization's master data management capability will also include people and processes in its definition. === People === Several roles should be staffed within MDM. Most prominently, the Data Owner and the Data Steward. Several people would likely be allocated to each role and each person responsible for a subset of Master Data (e.g. one data owner for employee master data, another for customer master data). The Data Owner is responsible for the requirements for data definition, data quality, data security, etc. as well as for compliance with data governance and data management procedures. The Data Owner should also be funding improvement projects in case of deviations from the requirements. The Data Steward is running the master data management on behalf of the data owner and probably also being an advisor to the Data Owner. === Processes === Master data management can be viewed as a "discipline for specialized quality improvement" defined by the policies and procedures put in place by a data governance organization. It has the objective of providing processes for collecting, aggregating, matching, consolidating, quality-assuring, persisting and distributing master data throughout an organization to ensure a common understanding, consistency, accuracy and control, in the ongoing maintenance and application use of that data. Processes commonly seen in master data management include source identification, data collection, data transformation, normalization, rule administration, error detection and correction, data consolidation, data storage, data distribution, data classification, taxonomy services, item master creation, schema mapping, product codification, data enrichment, hierarchy management, business semantics management and data governance. === Technology === A master data management tool can be used to support master data management by removing duplicates, standardizing data (mass maintaining), and incorporating rules to eliminate incorrect data from entering the system to create an authoritative source of master data. Master data are the products, accounts, and parties for which the business transactions are completed. Where the technology approach produces a "golden record" or relies on a "source of record" or "system of record", it is common to talk of where the data is "mastered". This is accepted terminology in the information technology industry, but care should be taken, both with specialists and with the wider stakeholder community, to avoid confusing the concept of "master data" with that of "mastering data". ==== Implementation models ==== There are several models for implementing a technology solution for master data management. These depend on an organization's core business, its corporate structure, and its goals. These include: Source of record Registry Consolidation Coexistence Transaction/centralized ===== Source of record ===== This model identifies a single application, database, or simpler source (e.g. a spreadsheet) as being the "source of record" (or "system of record" where solely application databases are relied on). The benefit of this model is its conceptual simplicity, but it may not fit with the realities of complex master data distribution in large organizations. The source of record can be federated, for example by groups of attributes (so that different attributes of a master data entity may have different sources of record) or geographically (so that different parts of an organization may have different master sources). Federation is only applicable in certain use cases, where there is a clear delineation of which subsets of records will be found in which sources. The source of record model can be applied more widely than simply to master data, for example to reference data. ==== Transmission of master data ==== There are several ways in which master data may be collated and distributed to other systems. This includes: Data consolidation – The process of capturing master data from multiple sources and integrating it into a single hub (operational data store) for replication to other destination systems. Data federation – The process of providing a single virtual view of master data from one or more sources to one or more destination systems. Data propagation – The process of copying master data from one system to another, typically through point-to-point interfaces in legacy systems. == Change management in implementation == Challenges in adopting master data management within large organizations often arise when stakeholders disagree on a "single version of the truth" concept is not affirmed by stakeholders, who believe that their local definition of the master data is necessary. For example, the product hierarchy used to manage inventory may be entirely different from the product hierarchies used to support marketing efforts or pay sales representatives. It is above all necessary to identify if different master data is genuinely required. If it is required, then the solution implemented (technology and process) must be able to allow multiple versions of the truth to exist but will prov

  Read more →
• 

  Golden record (informatics)

  In informatics, a golden record is the valid version of a data element (record) in a single source of truth system. It may refer to a database, specific table or data field, or any unit of information used. A golden copy is a consolidated data set, and is supposed to provide a single source of truth and a "well-defined version of all the data entities in an organizational ecosystem". Other names sometimes used include master source or master version. The term has been used in conjunction with data quality, master data management, and similar topics. (Different technical solutions exist, see master data management). == Master data == In master data management (MDM), the golden copy refers to the master data (master version) of the reference data which works as an authoritative source for the "truth" for all applications in a given IT landscape.

  Read more →
• 

  List of JavaScript libraries

  This is a list of notable JavaScript libraries. == Constraint programming == Cassowary (software) CHR.js == DOM (manipulation) oriented == Google Polymer Dojo Toolkit jQuery MooTools Prototype JavaScript Framework == Graphical/visualization (canvas, SVG, or WebGL related) == AnyChart Apache ECharts Babylon.js Chart.js Cytoscape D3.js Dojo Toolkit FusionCharts Google Charts JointJS p5.js Plotly.js Processing.js Raphaël RGraph SWFObject Teechart Three.js Velocity.js Verge3D Webix == GUI (Graphical user interface) and widget related == Angular (application platform) by Google AngularJS by Google Bootstrap Dojo Widgets Ext JS by Sencha Foundation by ZURB jQuery UI jQWidgets OpenUI5 by SAP Polymer (library) by Google qooxdoo React.js by Meta/Facebook Vue.js Webix WinJS Svelte === No longer actively developed === Glow Lively Kernel Script.aculo.us YUI Library == Pure JavaScript/Ajax == Google Closure Library JsPHP Microsoft's Ajax library MochiKit PDF.js Socket.IO Spry framework Underscore.js == Template systems == jQuery Mobile Mustache Jinja-JS Twig.js == Unit testing == Jasmine Mocha QUnit == Test automation == Playwright Cypress == Web-application related (MVC, MVVM) == Angular (application platform) by Google AngularJS by Google Backbone.js Echo Ember.js Enyo Express.js Ext JS Google Web Toolkit JsRender/JsViews Knockout Meteor Mojito MooTools Next.js Nuxt.js OpenUI5 by SAP Polymer (library) by Google Prototype JavaScript Framework qooxdoo React.js SproutCore svelte Vue.js == Other == Blockly Cannon.js MathJax Modernizr TensorFlow Brain.js

  Read more →
• 

  Microsoft Query

  Microsoft Query is a visual method of creating database queries using examples based on a text string, the name of a document or a list of documents. The QBE system converts the user input into a formal database query using Structured Query Language (SQL) on the backend, allowing the user to perform powerful searches without having to explicitly compose them in SQL, and without even needing to know SQL. It is derived from Moshé M. Zloof's original Query by Example (QBE) implemented in the mid-1970s at IBM's Research Centre in Yorktown, New York. In the context of Microsoft Access, QBE is used for introducing students to database querying, and as a user-friendly database management system for small businesses. Microsoft Excel allows results of QBE queries to be embedded in spreadsheets.

  Read more →
• 

  Information explosion

  Information explosion is the rapid increase in the amount of published information or data and the effects of this abundance. As the amount of available data grows, the problem of managing the information becomes more difficult, which can lead to information overload. The Online Oxford English Dictionary indicates use of the phrase in a March 1964 New Statesman article. The New York Times first used the phrase in its editorial content in an article by Walter Sullivan on June 7, 1964, in which he described the phrase as "much discussed". The earliest known use of the phrase was in a speech about television by NBC president Pat Weaver at the Institute of Practitioners of Advertising in London on September 27, 1955. The speech was rebroadcast on radio station WSUI in Iowa City and excerpted in the Daily Iowan newspaper two months later. Many sectors are seeing this rapid increase in the amount of information available such as healthcare, supermarkets, and governments. Another sector that is being affected by this phenomenon is journalism. Such a profession, which in the past was responsible for the dissemination of information, may be suppressed by the overabundance of information today. Techniques to gather knowledge from an overabundance of electronic information (e.g., data fusion may help in data mining) have existed since the 1970s. Another common technique to deal with such amount of information is qualitative research. Such approaches aim to organize the information, synthesizing, categorizing and systematizing in order to be more usable and easier to search. == Growth patterns == The world's technological capacity to store information grew from, optimally compressed, 2.6 exabytes in 1986 to 15.7 in 1993, over 54.5 in 2000, and to 295 exabytes in 2007. The world's technological capacity to receive information through one-way broadcast networks was 432 exabytes of (optimally compressed) information in 1986, 715 (optimally compressed) exabytes in 1993, 1,200 (optimally compressed) exabytes in 2000, and 1,900 in 2007. The world's effective capacity to exchange information through two-way telecommunications networks was 0.281 exabytes of (optimally compressed) information in 1986, 0.471 in 1993, 2.2 in 2000, and 65 (optimally compressed) exabytes in 2007. A new metric that is being used in an attempt to characterize the growth in person-specific information, is the disk storage per person (DSP), which is measured in megabytes/person (where megabytes is 106 bytes and is abbreviated MB). Global DSP (GDSP) is the total rigid disk drive space (in MB) of new units sold in a year divided by the world population in that year. The GDSP metric is a crude measure of how much disk storage could possibly be used to collect person-specific data on the world population. In 1983, one million fixed drives with an estimated total of 90 terabytes were sold worldwide; 30MB drives had the largest market segment. In 1996, 105 million drives, totaling 160,623 terabytes were sold with 1 and 2 gigabyte drives leading the industry. By the year 2000, with 20GB drive leading the industry, rigid drives sold for the year are projected to total 2,829,288 terabytes Rigid disk drive sales to top $34 billion in 1997. According to Latanya Sweeney, there are three trends in data gathering today: Type 1. Expansion of the number of fields being collected, known as the “collect more” trend. Type 2. Replace an existing aggregate data collection with a person-specific one, known as the “collect specifically” trend. Type 3. Gather information by starting a new person-specific data collection, known as the “collect it if you can” trend. == Related terms == Since "information" in electronic media is often used synonymously with "data", the term information explosion is closely related to the concept of data flood (also dubbed data deluge). Sometimes the term information flood is used as well. All of those basically boil down to the ever-increasing amount of electronic data exchanged per time unit. A term that covers the potential negative effects of information explosion is information inflation. The awareness about non-manageable amounts of data grew along with the advent of ever more powerful data processing since the mid-1960s. == Challenges == Even though the abundance of information can be beneficial in several levels, some problems may be of concern such as privacy, legal and ethical guidelines, filtering and data accuracy. Filtering refers to finding useful information in the middle of so much data, which relates to the job of data scientists. A typical example of a necessity of data filtering (data mining) is in healthcare since in the next years is due to have EHRs (Electronic Health Records) of patients available. With so much information available, the doctors will need to be able to identify patterns and select important data for the diagnosis of the patient. On the other hand, according to some experts, having so much public data available makes it difficult to provide data that is actually anonymous. Another point to take into account is the legal and ethical guidelines, which relates to who will be the owner of the data and how frequently he/she is obliged to the release this and for how long. With so many sources of data, another problem will be accuracy of such. An untrusted source may be challenged by others, by ordering a new set of data, causing a repetition in the information. According to Edward Huth, another concern is the accessibility and cost of such information. The accessibility rate could be improved by either reducing the costs or increasing the utility of the information. The reduction of costs according to the author, could be done by associations, which should assess which information was relevant and gather it in a more organized fashion. == Web servers == As of August 2005, there were over 70 million web servers. As of September 2007 there were over 135 million web servers. == Blogs == According to Technorati, the number of blogs doubles about every 6 months with a total of 35.3 million blogs as of April 2006. This is an example of the early stages of logistic growth, where growth is approximately exponential, since blogs are a recent innovation. As the number of blogs approaches the number of possible producers (humans), saturation occurs, growth declines, and the number of blogs eventually stabilizes.

  Read more →
• 

  Certifying algorithm

  In theoretical computer science, a certifying algorithm is an algorithm that outputs, together with a solution to the problem it solves, a proof that the solution is correct. A certifying algorithm is said to be efficient if the combined runtime of the algorithm and a proof checker is slower by at most a constant factor than the best known non-certifying algorithm for the same problem. The proof produced by a certifying algorithm should be in some sense simpler than the algorithm itself, for otherwise any algorithm could be considered certifying (with its output verified by running the same algorithm again). Sometimes this is formalized by requiring that a verification of the proof take less time than the original algorithm, while for other problems (in particular those for which the solution can be found in linear time) simplicity of the output proof is considered in a less formal sense. For instance, the validity of the output proof may be more apparent to human users than the correctness of the algorithm, or a checker for the proof may be more amenable to formal verification. Implementations of certifying algorithms that also include a checker for the proof generated by the algorithm may be considered to be more reliable than non-certifying algorithms. For, whenever the algorithm is run, one of three things happens: it produces a correct output (the desired case), it detects a bug in the algorithm or its implication (undesired, but generally preferable to continuing without detecting the bug), or both the algorithm and the checker are faulty in a way that masks the bug and prevents it from being detected (undesired, but unlikely as it depends on the existence of two independent bugs). == Examples == Many examples of problems with checkable algorithms come from graph theory. For instance, a classical algorithm for testing whether a graph is bipartite would simply output a Boolean value: true if the graph is bipartite, false otherwise. In contrast, a certifying algorithm might output a 2-coloring of the graph in the case that it is bipartite, or a cycle of odd length if it is not. Any graph is bipartite if and only if it can be 2-colored, and non-bipartite if and only if it contains an odd cycle. Both checking whether a 2-coloring is valid and checking whether a given odd-length sequence of vertices is a cycle may be performed more simply than testing bipartiteness. Analogously, it is possible to test whether a given directed graph is acyclic by a certifying algorithm that outputs either a topological order or a directed cycle. It is possible to test whether an undirected graph is a chordal graph by a certifying algorithm that outputs either an elimination ordering (an ordering of all vertices such that, for every vertex, the neighbors that are later in the ordering form a clique) or a chordless cycle. And it is possible to test whether a graph is planar by a certifying algorithm that outputs either a planar embedding or a Kuratowski subgraph. The extended Euclidean algorithm for the greatest common divisor of two integers x and y is certifying: it outputs three integers g (the divisor), a, and b, such that ax + by = g. This equation can only be true of multiples of the greatest common divisor, so testing that g is the greatest common divisor may be performed by checking that g divides both x and y and that this equation is correct.

  Read more →
• 

  Network Abstraction Layer

  The Network Abstraction Layer (NAL) is a part of the H.264/AVC and HEVC video coding standards. The main goal of the NAL is the provision of a "network-friendly" video representation addressing "conversational" (video telephony) and "non conversational" (storage, broadcast, or streaming) applications. NAL has achieved a significant improvement in application flexibility relative to prior video coding standards. == Introduction == An increasing number of services and growing popularity of high definition TV are creating greater needs for higher coding efficiency. Moreover, other transmission media such as cable modem, xDSL, or UMTS offer much lower data rates than broadcast channels, and enhanced coding efficiency can enable the transmission of more video channels or higher quality video representations within existing digital transmission capacities. Video coding for telecommunication applications has diversified from ISDN and T1/E1 service to embrace PSTN, mobile wireless networks, and LAN/Internet network delivery. Throughout this evolution, continued efforts have been made to maximize coding efficiency while dealing with the diversification of network types and their characteristic formatting and loss/error robustness requirements. The H.264/AVC and HEVC standards are designed for technical solutions including areas like broadcasting (over cable, satellite, cable modem, DSL, terrestrial, etc.) interactive or serial storage on optical and magnetic devices, conversational services, video-on-demand or multimedia streaming, multimedia messaging services, etc. Moreover, new applications may be deployed over existing and future networks. This raises the question about how to handle this variety of applications and networks. To address this need for flexibility and customizability, the design covers a NAL that formats the Video Coding Layer (VCL) representation of the video and provides header information in a manner appropriate for conveyance by a variety of transport layers or storage media. The NAL is designed in order to provide "network friendliness" to enable simple and effective customization of the use of VCL for a broad variety of systems. The NAL facilitates the ability to map VCL data to transport layers such as: RTP/IP for any kind of real-time wire-line and wireless Internet services. File formats, e.g., ISO MP4 for storage and MMS. H.32X for wireline and wireless conversational services. MPEG-2 systems for broadcasting services, etc. The full degree of customization of the video content to fit the needs of each particular application is outside the scope of the video coding standardization effort, but the design of the NAL anticipates a variety of such mappings. Some key concepts of the NAL are NAL units, byte stream, and packet formats uses of NAL units, parameter sets, and access units. A short description of these concepts is given below. == NAL units == The coded video data is organized into NAL units, each of which is effectively a packet that contains an integer number of bytes. The first byte of each H.264/AVC NAL unit is a header byte that contains an indication of the type of data in the NAL unit. For HEVC the header was extended to two bytes. All the remaining bytes contain payload data of the type indicated by the header. The NAL unit structure definition specifies a generic format for use in both packet-oriented and bitstream-oriented transport systems, and a series of NAL units generated by an encoder is referred to as a NAL unit stream. == NAL Units in Byte-Stream Format Use == Some systems require delivery of the entire or partial NAL unit stream as an ordered stream of bytes or bits within which the locations of NAL unit boundaries need to be identifiable from patterns within the coded data itself. For use in such systems, the H.264/AVC and HEVC specifications define a byte stream format. In the byte stream format, each NAL unit is prefixed by a specific pattern of three bytes called a start code prefix. The boundaries of the NAL unit can then be identified by searching the coded data for the unique start code prefix pattern. The use of emulation prevention bytes guarantees that start code prefixes are unique identifiers of the start of a new NAL unit. A small amount of additional data (one byte per video picture) is also added to allow decoders that operate in systems that provide streams of bits without alignment to byte boundaries to recover the necessary alignment from the data in the stream. Additional data can also be inserted in the byte stream format that allows expansion of the amount of data to be sent and can aid in achieving more rapid byte alignment recovery, if desired. == NAL Units in Packet-Transport System Use == In other systems (e.g., IP/RTP systems), the coded data is carried in packets that are framed by the system transport protocol, and identification of the boundaries of NAL units within the packets can be established without use of start code prefix patterns. In such systems, the inclusion of start code prefixes in the data would be a waste of data carrying capacity, so instead the NAL units can be carried in data packets without start code prefixes. == VCL and Non-VCL NAL Units == NAL units are classified into VCL and non-VCL NAL units. VCL NAL units contain the data that represents the values of the samples in the video pictures. Non-VCL NAL units contain any associated additional information such as parameter sets (important header data that can apply to a large number of VCL NAL units) and supplemental enhancement information (timing information and other supplemental data that may enhance usability of the decoded video signal but are not necessary for decoding the values of the samples in the video pictures). == Parameter Sets == A parameter set contains shared configuration data that is carried in non-VCL NAL units. Parameter sets are typically reused when decoding many coded pictures within a video sequence. Each VCL NAL unit references a picture parameter set (PPS), which in turn references a sequence parameter set (SPS). There are two types of parameter sets: Sequence parameter set (SPS), which specifies mostly constant configuration such as resolution, bit depth, or chroma format. (For a concrete implementation, see FFmpeg's SPS struct.) Picture parameter set (PPS), which applies on top of an SPS, and specifies configuration such as QP offsets. (For a concrete implementation, see FFmpeg's PPS struct.) The sequence and picture parameter-set mechanism decouples the transmission of infrequently changing information from the transmission of coded representations of the values of the samples in the video pictures. Each VCL NAL unit contains an identifier that refers to the content of the relevant picture parameter set and each picture parameter set contains an identifier that refers to the content of the relevant sequence parameter set. In this manner, a small amount of data (the identifier) can be used to refer to a larger amount of information (the parameter set) without repeating that information within each VCL NAL unit. Sequence and picture parameter sets can be sent well ahead of the VCL NAL units that they apply to, and can be repeated to provide robustness against data loss. In some applications, parameter sets may be sent within the channel that carries the VCL NAL units (termed "in-band" transmission). In other applications, it can be advantageous to convey the parameter sets "out-of-band" using a more reliable transport mechanism than the video channel itself. == Access Units == A set of NAL units in a specified form is referred to as an access unit. The decoding of each access unit results in one decoded picture. Each access unit contains a set of VCL NAL units that together compose a primary coded picture. It may also be prefixed with an access unit delimiter to aid in locating the start of the access unit. Some supplemental enhancement information containing data such as picture timing information may also precede the primary coded picture. The primary coded picture consists of a set of VCL NAL units consisting of slices or slice data partitions that represent the samples of the video picture. Following the primary coded picture may be some additional VCL NAL units that contain redundant representations of areas of the same video picture. These are referred to as redundant coded pictures, and are available for use by a decoder in recovering from loss or corruption of the data in the primary coded pictures. Decoders are not required to decode redundant coded pictures if they are present. Finally, if the coded picture is the last picture of a coded video sequence (a sequence of pictures that is independently decodable and uses only one sequence parameter set), an end of sequence NAL unit may be present to indicate the end of the sequence; and if the coded picture is the last coded picture in the entire NAL unit stream, an end of stream NAL unit may be present to

  Read more →
• 

  Operational system

  An operational system is a term used in data warehousing to refer to a system that is used to process the day-to-day transactions of an organization. These systems are designed in a manner that processing of day-to-day transactions is performed efficiently and the integrity of the transactional data is preserved. == Synonyms == Sometimes operational systems are referred to as operational databases, transaction processing systems, or online transaction processing systems (OLTP). However, the use of the last two terms as synonyms may be confusing, because operational systems can be batch processing systems as well. Any enterprise must necessarily maintain a lot of data about its operation.

  Read more →
• 

  Cancer Likelihood in Plasma

  Cancer Likelihood in Plasma (CLiP) refers to a set of ensemble learning methods for integrating various genomic features useful for the noninvasive detection of early cancers from blood plasma. An application of this technique for early detection of lung cancer (Lung-CLiP) was originally described by Chabon et al. (2020) from the labs of Ash Alizadeh and Max Diehn at Stanford. This method relies on several improvements to cancer personalized profiling by deep sequencing (CAPP-Seq) for analysis of circulating tumor DNA (ctDNA). The CLiP technique integrates multiple distinctive genomic features of a cancer of interest findings within a machine-learning framework for cancer detection. For example, studies have shown that the majority of somatic mutations found in cell-free DNA (cfDNA) are not tumor derived, but instead reflect clonal hematopoeisis (also known as CHIP). Even though CHIP tends to target specific genes, it also involves many generally non-recurrent mutations that can be shed from leukocytes and detected in cfDNA, regardless of whether profiling patients with cancer and healthy adults. However, genuine tumor derived ctDNA mutations can be distinguished from CHIP-derived mutations. This is because unlike tumor-derived mutations, CHIP-derived mutations that are shed from leukocytes into plasma tend to occur on longer cfDNA fragments, and to lack specific mutational signatures such as those associated with tobacco smoking in lung cancer that are also found in tumor derived ctDNA molecules. CLiP integrates these features within hierarchical ensemble machine learning models that consider somatic mutations and copy number alternations, among other features. While the CLiP method is unique in relying exclusively on mutations and copy number alterations, it is related to a variety of other liquid biopsy methods being commercially developed for early cancer detection using ctDNA and proteins (e.g., CancerSEEK / DETECT-A ), cfDNA fragmentation patterns (e.g., DELFI), and DNA methylation (e.g., cfMeDIP-Seq, Grail). While the CLiP method has not yet been broadly applied for population-based cancer screening, it has been shown to distinguish discriminate early-stage lung cancers from risk-matched controls across multiple cohorts of patients enrolled across the US.

  Read more →
• 

  Hybrid algorithm

  A hybrid algorithm is an algorithm that combines two or more other algorithms that solve the same problem, either choosing one based on some characteristic of the data, or switching between them over the course of the algorithm. This is generally done to combine desired features of each, so that the overall algorithm is better than the individual components. "Hybrid algorithm" does not refer to simply combining multiple algorithms to solve a different problem – many algorithms can be considered as combinations of simpler pieces – but only to combining algorithms that solve the same problem, but differ in other characteristics, notably performance. == Examples == In computer science, hybrid algorithms are very common in optimized real-world implementations of recursive algorithms, particularly implementations of divide-and-conquer or decrease-and-conquer algorithms, where the size of the data decreases as one moves deeper in the recursion. In this case, one algorithm is used for the overall approach (on large data), but deep in the recursion, it switches to a different algorithm, which is more efficient on small data. A common example is in sorting algorithms, where the insertion sort, which is inefficient on large data, but very efficient on small data (say, five to ten elements), is used as the final step, after primarily applying another algorithm, such as merge sort or quicksort. Merge sort and quicksort are asymptotically optimal on large data, but the overhead becomes significant if applying them to small data, hence the use of a different algorithm at the end of the recursion. A highly optimized hybrid sorting algorithm is Timsort, which combines merge sort, insertion sort, together with additional logic (including binary search) in the merging logic. A general procedure for a simple hybrid recursive algorithm is short-circuiting the base case, also known as arm's-length recursion. In this case whether the next step will result in the base case is checked before the function call, avoiding an unnecessary function call. For example, in a tree, rather than recursing to a child node and then checking if it is null, checking null before recursing. This is useful for efficiency when the algorithm usually encounters the base case many times, as in many tree algorithms, but is otherwise considered poor style, particularly in academia, due to the added complexity. Another example of hybrid algorithms for performance reasons are introsort and introselect, which combine one algorithm for fast average performance, falling back on another algorithm to ensure (asymptotically) optimal worst-case performance. Introsort begins with a quicksort, but switches to a heap sort if quicksort is not progressing well; analogously introselect begins with quickselect, but switches to median of medians if quickselect is not progressing well. Centralized distributed algorithms can often be considered as hybrid algorithms, consisting of an individual algorithm (run on each distributed processor), and a combining algorithm (run on a centralized distributor) – these correspond respectively to running the entire algorithm on one processor, or running the entire computation on the distributor, combining trivial results (a one-element data set from each processor). A basic example of these algorithms are distribution sorts, particularly used for external sorting, which divide the data into separate subsets, sort the subsets, and then combine the subsets into totally sorted data; examples include bucket sort and flashsort. However, in general distributed algorithms need not be hybrid algorithms, as individual algorithms or combining or communication algorithms may be solving different problems. For example, in models such as MapReduce, the Map and Reduce step solve different problems, and are combined to solve a different, third problem.

  Read more →
• 

  Token maxxing

  Token Maxxing or Token Maxing is a metric used in an attempt to track productivity in the workplace especially for those using Artificial Intelligence (AI) based services. AI services charge for each token which represent units of effort expended by an AI service to solve a problem. Some believe that token consumption equates to productivity and thus can be used as a metric to monitor an employee's work. Supporters believe that higher token usage indicates higher productivity and higher utilization of powerful AI services. This also suggests that those not consuming enough tokens may be less productive and underutilizing powerful AI services. This belief might lead to an environment that incentivizes higher token usage to predict increased productivity. Critics of token maxxing as a metric claim that prudent workers will maximize any metric that management wants increased to gain a workplace advantage. For example: Engineers in the tech industries pressed to consume as many tokens as possible might run several AI agents in tandem, enter longer input prompts, or automate their tasks to maximize their token consumption. To management, this higher token usage may indicate potential productivity, but in reality may cause additional token costs, worker burnout, or actually create more bloated code of lower quality. Another claim is AI service companies potentially benefit from such an emphasis on token consumption and actively encourage the trend. Some developers have publicly advocated the practice. Developer Sigrid Jin, who said he used 50 billion tokens in a single year, has argued that maximizing token consumption is the best way to understand the value of AI, advising others to spend as much on AI usage as they pay in rent to obtain a return on investment. == See Also == Goodhart's law Perverse incentive Jevons Paradox

  Read more →
• 

  Archetype (information science)

  In the field of informatics, an archetype is a formal re-usable model of a domain concept. Traditionally, the term archetype is used in psychology to mean an idealized model of a person, personality or behaviour (see Archetype). The usage of the term in informatics is derived from this traditional meaning, but applied to domain modelling instead. An archetype is defined by the OpenEHR Foundation (for health informatics) as follows: An archetype is a computable expression of a domain content model in the form of structured constraint statements, based on some reference model. openEHR archetypes are based on the openEHR reference model. Archetypes are all expressed in the same formalism. In general, they are defined for wide re-use, however, they can be specialized to include local particularities. They can accommodate any number of natural languages and terminologies. == Formal specifications == The modern archetype formalism is specified and maintained by the openEHR Foundation, and although originally developed for the health IT domain, is completely domain-independent, and has been used in geospatial modelling, telecommunications, and defence. The archetype formalism consists of a number of specifications including: 'ADL 1.4': original release of Archetype Definition Language (ADL) and Archetype Object Model (AOM); widely implemented in health IT domain; 'ADL 2': modern release of Archetype Definition Language (ADL), Archetype Object Model (AOM), Archetype Identification specification and Archetype Technology Overview. The Archetype Technology Overview provides a short technical overview of the archetype formalism useful for new users. The ADL/AOM 1.4 specifications were provided to ISO TC 215 in 2008 by the openEHR Foundation and became the ISO 13606-2 standard, extant until 2019. ISO TC 215 accepted the AOM 2 specification as the basis for a revision of this standard, which was issued in 2019. In late 2015, the Object Management Group (OMG) accepted an RfP entitled 'Archetype Modeling Language (AML)' as a new candidate standard. This specification is a form of ADL re-engineered as a UML profile so as to enable archetype modelling to be supported within UML tools. == Tools == A number of tools area available for working with archetypes. Most are listed on the openEHR modelling tools page. They include: ADL Designer, a modern AOM2-based web editing application Archetype Editor, an original desktop clinical modelling tool Template Designer, an original desktop clinical templating tool LinkEHR, an archetype and data integration tool ADL Workbench, reference compiler and visualiser tool == Example ==

  Read more →
• 

  Least-squares spectral analysis

  Least-squares spectral analysis (LSSA) is a class of methods for estimating a frequency spectrum by fitting sinusoids to data using a least-squares fit. Unlike Fourier analysis, the most widely used spectral method in science, data need not be equally spaced to use LSSA. Furthermore, while Fourier analysis generally amplifies long-period noise in long or gapped records, LSSA mitigates such problems. The first strictly least-squares LSSA method was developed in 1969 and 1971, and is known as the Vaníček method or the Gauss–Vaniček method, after its inventor Petr Vaníček and Carl Friedrich Gauss, the inventor of the least-squares method for error minimization. A widely known LSSA variant is the Lomb method or the Lomb–Scargle periodogram, based on dated computational simplifications of the Vaníček method introduced in the 1970s and 1980s, first by Nicholas R. Lomb and later by Jeffrey D. Scargle. Other LSSA variants have been subsequently developed. == Historical background == The close connections between Fourier analysis, the periodogram, and the least-squares fitting of sinusoids have been known for a long time. However, most developments are restricted to complete data sets of equally spaced samples. In 1963, Freek J. M. Barning of Mathematisch Centrum, Amsterdam, handled unequally spaced data by similar techniques, including both a periodogram analysis equivalent to what nowadays is called the Lomb method and least-squares fitting of selected frequencies of sinusoids determined from such periodograms — and connected by a procedure known today as the matching pursuit with post-back fitting or the orthogonal matching pursuit. Petr Vaníček, a Canadian geophysicist and geodesist of the University of New Brunswick, proposed in 1969 also the matching-pursuit approach for equally and unequally spaced data, which he called "successive spectral analysis" and the result a "least-squares periodogram". He generalized this method to account for any systematic components beyond a simple mean, such as a "predicted linear (quadratic, exponential, ...) secular trend of unknown magnitude", and applied it to a variety of samples, in 1971. Vaníček's strictly least-squares method was then simplified in 1976 by Nicholas R. Lomb of the University of Sydney, who pointed out its close connection to periodogram analysis. Subsequently, the definition of a periodogram of unequally spaced data was modified and analyzed by Jeffrey D. Scargle of NASA Ames Research Center, who showed that, with minor changes, it becomes identical to Lomb's least-squares formula for fitting individual sinusoid frequencies. Scargle states that his paper "does not introduce a new detection technique, but instead studies the reliability and efficiency of detection with the most commonly used technique, the periodogram, in the case where the observation times are unevenly spaced," and further points out regarding least-squares fitting of sinusoids compared to periodogram analysis, that his paper "establishes, apparently for the first time, that (with the proposed modifications) these two methods are exactly equivalent." Press summarizes the development this way: A completely different method of spectral analysis for unevenly sampled data, one that mitigates these difficulties and has some other very desirable properties, was developed by Lomb, based in part on earlier work by Barning and Vanicek, and additionally elaborated by Scargle. In 1989, Michael J. Korenberg of Queen's University in Kingston, Ontario, developed the "fast orthogonal search" method of more quickly finding a near-optimal decomposition of spectra or other problems, similar to the technique that later became known as the orthogonal matching pursuit. == Development of LSSA and variants == === The Vaníček method === In the Vaníček method, a discrete data set is approximated by a weighted sum of sinusoids of progressively determined frequencies using a standard linear regression or least-squares fit. The frequencies are chosen using a method similar to Barning's, but going further in optimizing the choice of each successive new frequency by picking the frequency that minimizes the residual after least-squares fitting (equivalent to the fitting technique now known as matching pursuit with pre-backfitting). The number of sinusoids must be less than or equal to the number of data samples (counting sines and cosines of the same frequency as separate sinusoids). The relationship between the DFT and the approximation of trigonometric functions using the least-squares method is well explained in (Strutz, 2017). A data vector Φ is represented as a weighted sum of sinusoidal basis functions, tabulated in a matrix A by evaluating each function at the sample times, with weight vector x: ϕ ≈ A x , {\displaystyle \phi \approx {\textbf {A}}x,} where the weights vector x is chosen to minimize the sum of squared errors in approximating Φ. The solution for x is closed-form, using standard linear regression: x = ( A T A ) − 1 A T ϕ . {\displaystyle x=({\textbf {A}}^{\mathrm {T} }{\textbf {A}})^{-1}{\textbf {A}}^{\mathrm {T} }\phi .} Here the matrix A can be based on any set of functions mutually independent (not necessarily orthogonal) when evaluated at the sample times; functions used for spectral analysis are typically sines and cosines evenly distributed over the frequency range of interest. If we choose too many frequencies in a too-narrow frequency range, the functions will be insufficiently independent, the matrix ill-conditioned, and the resulting spectrum meaningless. When the basis functions in A are orthogonal (that is, not correlated, meaning the columns have zero pair-wise dot products), the matrix ATA is diagonal; when the columns all have the same power (sum of squares of elements), then that matrix is an identity matrix times a constant, so the inversion is trivial. The latter is the case when the sample times are equally spaced and sinusoids chosen as sines and cosines equally spaced in pairs on the frequency interval 0 to a half cycle per sample (spaced by 1/N cycles per sample, omitting the sine phases at 0 and maximum frequency where they are identically zero). This case is known as the discrete Fourier transform, slightly rewritten in terms of measurements and coefficients. x = A T ϕ {\displaystyle x={\textbf {A}}^{\mathrm {T} }\phi } — DFT case for N equally spaced samples and frequencies, within a scalar factor. === The Lomb method === Trying to lower the computational burden of the Vaníček method in 1976 (no longer an issue), Lomb proposed using the above simplification in general, except for pair-wise correlations between sine and cosine bases of the same frequency, since the correlations between pairs of sinusoids are often small, at least when they are not tightly spaced. This formulation is essentially that of the traditional periodogram but adapted for use with unevenly spaced samples. The vector x is a reasonably good estimate of an underlying spectrum, but since we ignore any correlations, Ax is no longer a good approximation to the signal, and the method is no longer a least-squares method — yet in the literature continues to be referred to as such. Rather than just taking dot products of the data with sine and cosine waveforms directly, Scargle modified the standard periodogram formula so to find a time delay τ {\displaystyle \tau } first, such that this pair of sinusoids would be mutually orthogonal at sample times t j {\displaystyle t_{j}} and also adjusted for the potentially unequal powers of these two basis functions, to obtain a better estimate of the power at a frequency. This procedure made his modified periodogram method exactly equivalent to Lomb's method. Time delay τ {\displaystyle \tau } by definition equals to tan ⁡ 2 ω τ = ∑ j sin ⁡ 2 ω t j ∑ j cos ⁡ 2 ω t j . {\displaystyle \tan {2\omega \tau }={\frac {\sum _{j}\sin 2\omega t_{j}}{\sum _{j}\cos 2\omega t_{j}}}.} Then the periodogram at frequency ω {\displaystyle \omega } is estimated as: P x ( ω ) = 1 2 [ [ ∑ j X j cos ⁡ ω ( t j − τ ) ] 2 ∑ j cos 2 ⁡ ω ( t j − τ ) + [ ∑ j X j sin ⁡ ω ( t j − τ ) ] 2 ∑ j sin 2 ⁡ ω ( t j − τ ) ] , {\displaystyle P_{x}(\omega )={\frac {1}{2}}\left[{\frac {\left[\sum _{j}X_{j}\cos \omega (t_{j}-\tau )\right]^{2}}{\sum _{j}\cos ^{2}\omega (t_{j}-\tau )}}+{\frac {\left[\sum _{j}X_{j}\sin \omega (t_{j}-\tau )\right]^{2}}{\sum _{j}\sin ^{2}\omega (t_{j}-\tau )}}\right],} which, as Scargle reports, has the same statistical distribution as the periodogram in the evenly sampled case. At any individual frequency ω {\displaystyle \omega } , this method gives the same power as does a least-squares fit to sinusoids of that frequency and of the form: ϕ ( t ) = A sin ⁡ ω t + B cos ⁡ ω t . {\displaystyle \phi (t)=A\sin \omega t+B\cos \omega t.} In practice, it is always difficult to judge if a given Lomb peak is significant or not, especially when the nature of the noise is unknown, so for example a false-alarm spectr

  Read more →