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  • Aphelion (software)

    Aphelion (software)

    The Aphelion Imaging Software Suite is a software suite that includes three base products - Aphelion Lab, Aphelion Dev, and Aphelion SDK for addressing image processing and image analysis applications. The suite also includes a set of extension programs to implement specific vertical applications that benefit from imaging techniques. The Aphelion software products can be used to prototype and deploy applications, or can be integrated, in whole or in part, into a user's system as processing and visualization libraries whose components are available as both DLLs or .Net components. == History and evolution == The development of Aphelion started in 1995 as a joint project of a French company, ADCIS S.A., and an American company, Amerinex Applied Imaging, Inc. (AAI) Aphelion's image processing and analysis functions were made from operators available from the KBVision software developed and sold by Amerinex's predecessor, Amerinex Artificial Intelligence Inc. In the 1990s, the XLim software library was developed at the Center of Mathematical Morphology of Mines ParisTech, and both companies carried out its development tasks. The first version of Aphelion was completed and released in April 1996. Successive versions were released before the first official stable release in December 1996 at the Photonics East conference in Boston and the Solutions Vision show in Paris in January 1997, where at the latter it competed with Stemmer Imaging's CVB imaging toolbox. In 1998, version 2.3 of Aphelion for Windows 98 was released, and its user base was growing in both France and the United States. Version 3.0, totally rewritten to take advantage of Microsoft's then-recent ActiveX technology, was officially released in 2000. It also became available as a « Developer » version, for rapid prototyping of applications using its intuitive GUI and the macro recording capability, and a « Core » version, including the full library as a set of ActiveX components to be used by software developers, integrators and original equipment manufacturers (OEM). As AAI turned its focus to security, in 2001, ADCIS took the lead on developing Aphelion. AAI focused on millimeter wave scanners for concealed weapon detection at airports, and eventually merged with Millimetrics to become Millivision. In 2004, ADCIS specified version 4.0 of Aphelion. The set of image processing/analysis functions was rewritten one more time to be compatible with the .NET technology and the emergence of 64 bit architecture PCs. In addition, the GUI was redesigned to address two usage types: a semi-automatic use where the user is guided through the different steps of functions, and a fully automatic use where the expert user can quickly invoke imaging functions. Its first release was presented at the IPOT exhibition in Birmingham, UK the same year. During the Vision Show in Paris in October 2008, the new Aphelion Lab product was launched for users that are not specialists in image processing. It is easier to use, and only includes fewer image processing functions. It was then included in the Aphelion Image Processing Suite, consisting of Aphelion Dev (replacing Aphelion Developer), Aphelion Lab, Aphelion SDK (replacing Aphelion Core), and a set of extensions. Nowadays, ADCIS is still working on the suite, and updated versions with new extensions and functionalities continually become available from the websites of both companies. In 2015, support was added for very large images and scan microscope images (virtual slides compound into a very large JPEG 2000 image) for high throughput imaging, and new specific extensions were also added. In late 2015, ADCIS announced Aphelion's port for tablets and smartphones, for vertical applications. The name "Aphelion" comes from the astronomical term of the same name, meaning the point on a planet rotating around the Sun where it lies farthest from it, applying the term in a metaphorical sense. Unix was the operating system used on scientific workstations in the 1990s, such as on the workstations manufactured by market leader Sun Microsystems, which Windows suite Aphelion was quite removed from. == Description == Aphelion is a software suite to be used for image processing and image analysis. It supports 2D and 3D, monochrome, color, and multi-band images. It is developed by ADCIS, a French software house located in Saint-Contest, Calvados, Normandy. Aphelion is widely used in the scientific/industry community to solve basic and complex imaging applications. First, the imaging application is quickly developed from the Graphical User Interface, involving a set of functions that can be automatically recorded into a macro command. The macro languages available in Aphelion (i.e. BasicScript, Python, and C#) help to process batch of images, and prompt the user if needed for specific parameters that are applied to the imaging functions. All Aphelion image processing functions are written in C++, and the Aphelion user interface is written in C#. C++ functions can be called from the C# language thanks the use of dedicated wrappers. The main principle of image processing is to automatically process pixels of a digital image, then extract one or more objects of interest (i.e. cells in the field of biology, inclusions in the field of material science) and compute one or more measurements on those objects to quantify the image and generate a verdict (good image, image with defects, cancerous cells). In other words, starting from an image, pixels are processed by a set of successive functions or operators until only measurements are computed and used as the input of a 3rd party system or a classification software that will classify objects of interest that have been extracted during the imaging process. An acquisition system such as a digital camera, a video camera, an optical or electron microscope, a medical scanner, or a smartphone can be used to capture images. The set of values or pixels can be processed as a 1D image (1D signal), a 2D image (array of pixel values corresponding to a monochrome or color image), or a 3D image displayed using volume rendering (array of voxels in the 3D space) or displaying surfaces by using 3D rendering. A 2D color image is made of 3 value pixels (typically Red, Green, and Blue information or another color space), and a 3D image is made of monochrome, color (indexed color are often used), multispectral, or hyperspectral data. When dealing with videos, an additional band is added corresponding to temporal information. The Aphelion Software Suite includes three base products, and a set of optional extensions for specific applications: Aphelion Lab: Entry-level package for non-experts in image processing. It helps to quickly segment an image in a semi-automatic or manual ways, and compute a set of measurements computed on objects of interest that have been extracted during the segmentation process. A set of wizards guides the user from image acquisition to report generation. Aphelion Dev: Full imaging environment including over 450 functions to develop and deploy an application that involves image processing and analysis. It also includes a set of macro-command languages to automate any application to be invoked from the user interface. It also helps to run the imaging algorithm on more than one image that are stored on disk, available on the network, or captured by an acquisition device. Aphelion libraries for image processing and visualization are provided in Aphelion Dev as DLLs and .Net components. Aphelion SDK: A set of libraries to develop a stand-alone application with a custom interface based on the Aphelion libraries. This software development kit including display, processing and analysis functions that can be used by software developers and OEMs. It is provided as DLLs and .Net components. The stand-alone application is typically developed in C# on one computer, and then deployed on multiple PCs and systems. A set of optional extensions can be added to the « Aphelion Dev » product, depending on the application. An evaluation version of Aphelion can be run on a PC for 30 days. A permanent version of Aphelion is available based on a perpetual license. Upgrades are available through a maintenance agreement based on a yearly fee. Technical support is provided by the engineers who are developing the product. The goal of image processing is usually to extract object(s) of interest in an image, and then to classify them based on some characteristics such as shape, density, position, etc. Using Aphelion, this goal is achieved by performing the following tasks: Load an image from disk or acquire an image using an acquisition device. Enhance the image removing noise or modifying its contrast. Segment the image extracting objects of interest to be measured and analyzed. Typically, for simple applications, a threshold is performed to generate a binary image. Then, morphological operators are applied to clean the image and only keep obj

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  • Facebook Messenger

    Facebook Messenger

    Messenger (formerly known as Facebook Messenger) is an American proprietary instant messaging service developed by Meta Platforms, the company that operates Facebook. Originally developed as Facebook Chat in 2008, the client application of Messenger is currently available on iOS and Android mobile platforms, Windows and macOS desktop platforms, through the Messenger.com web application, and on the standalone Meta Portal hardware. Messenger is used to send messages and exchange photos, videos, stickers, audio, and files, and also react to other users' messages and interact with bots. The service also supports voice and video calling. The standalone apps support using multiple accounts, conversations with end-to-end encryption, and playing games. There are also group chats where you can connect with multiple people at once in a private space such as Panama Chat. With a monthly userbase of over 1 billion people, it is among the largest social media platforms. == History == Following tests of a new instant messaging platform on Facebook in March 2008, the feature, then-titled "Facebook Chat", was gradually released to users in April 2008. Facebook revamped its messaging platform in November 2010, and subsequently acquired group messaging service Beluga in March 2011, which the company used to launch its standalone iOS and Android mobile apps on August 9, 2011. Facebook later launched a BlackBerry version in October 2011. An app for Windows Phone, though lacking features including voice messaging and chat heads, was released in March 2014. In April 2014, Facebook announced that the messaging feature would be removed from the main Facebook app and users will be required to download the separate Messenger app. An iPad-optimized version of the iOS app was released in July 2014. On April 8, 2015, Facebook launched a website interface for Messenger. A Tizen app was released on July 13, 2015. Facebook launched Messenger for Windows 10 in April 2016. In October 2016, Facebook released Messenger Lite, a stripped-down version of Messenger with a reduced feature set. The app is aimed primarily at old Android phones and regions where high-speed Internet is not widely available. In April 2017, Messenger Lite was expanded to 132 more countries. In May 2017, Facebook revamped the design for Messenger on Android and iOS, bringing a new home screen with tabs and categorization of content and interactive media, red dots indicating new activity, and relocated sections. Facebook announced a Messenger program for Windows 7 in a limited beta test in November 2011. The following month, Israeli blog TechIT leaked a download link for the program, with Facebook subsequently confirming and officially releasing the program. The program was eventually discontinued in March 2014. A Firefox web browser add-on was released in December 2012, but was also discontinued in March 2014. In December 2017, Facebook announced Messenger Kids, a new app aimed for persons under 13 years of age. The app comes with some differences compared to the standard version. In 2019, Messenger announced to be the 2nd most downloaded mobile app of the decade, from 2011 to 2019. In December 2019, Messenger dropped support for users to sign in using only a mobile number, meaning that users must sign in to a Facebook account in order to use the service. In March 2020, Facebook started to ship its dedicated Messenger for macOS app through the Mac App Store. The app is currently live in regions including France, Australia, Mexico, Poland, and many others. In April 2020, Facebook began rolling out a new feature called Messenger Rooms, a video chat feature that allows users to chat with up to 50 people at a time. The feature rivals Zoom, an application that gained a lot of popularity during the COVID-19 pandemic. Privacy concerns arose since the feature uses the same data collection policies as mainstream Facebook. In July 2020, Facebook added a new feature in Messenger that lets iOS users to use Apple's Face ID or Touch ID to lock their chats. The feature is called App Lock and is a part of several changes in Messenger regarding privacy and security. The option to view only "Unread Threads" was removed from the inbox, requiring the account holder to scroll through the entire inbox to be certain every unread message has been seen. On October 13, 2020, the Messenger application introduced cross-app messaging with Instagram, which was launched in September 2021. In addition to the integrated messaging, the application announced the introduction of a new logo, which should be an amalgamation of the Messenger and Instagram logo. The desktop app of Messenger was shut down on December 15, 2025. Messaging services were moved to the Facebook website or Messenger's site for those without an account on the former. The Messenger site was discontinued on April 16, 2026. Messaging services were moved to the Facebook website on the morning of April 17, 2026 without an Messenger account on the former to use Facebook account. == Features == The following is a table of features available in Messenger, as well as their geographical coverage and what devices they are available on. In addition there is a vanishing message feature. In addition there is an audio recording feature which allows audio recordings of up to one minute which may or may not be vanishing: === Messenger Rooms === It is a video conferencing feature of Messenger. It allows users to add up to 50 people at a time. Messenger Rooms does not require a Facebook account. Messenger Rooms competes with other services such as Zoom. Back in 2014, Facebook introduced an unrelated, stand-alone application named Rooms, letting users create places for users with similar interests, with users being anonymous to others. This was shut down in December 2015. In April 2020, during the COVID-19 pandemic, Facebook revealed video conferencing features for Messenger called Messenger Rooms. This was seen as a response to the popularity of other video conferencing platforms such as Zoom and Skype in the midst of the COVID-19 pandemic. Messenger Rooms allows users to add up to 50 people per room, without restrictions on time. It does not require a Facebook account or a separate app from Messenger. When used, it only prompts the user for basic information. Users can add 360° virtual backgrounds, mood lighting, and other AR effects as well as share screens. To prevent unwanted participants from joining, users can lock rooms and remove participants. Some have voiced concerns in regards to Messenger Room's privacy and how its parent, Facebook, handles data. Messenger Rooms, unlike some of its competitors, does not use end-to-end encryption. In addition, there have been concerns over how Messenger Rooms collects user data. == Monetization == In January 2017, Facebook announced that it was testing showing advertisements in Messenger's home feed. At the time, the testing was limited to a "small number of users in Australia and Thailand", with the ad format being swipe-based carousel ads. In July, the company announced that they were expanding the testing to a global audience. Stan Chudnovsky, head of Messenger, told VentureBeat that "We'll start slow ... When the average user can be sure to see them we truly don't know because we're just going to be very data-driven and user feedback-driven on making that decision". Facebook told TechCrunch that the advertisements' placement in the inbox depends on factors such as thread count, phone screen size, and pixel density. In a TechCrunch editorial by Devin Coldewey, he described the ads as "huge" in the space they occupy, "intolerable" in the way they appear in the user interface, and "irrelevant" due to the lack of context. Coldewey finished by writing "Advertising is how things get paid for on the internet, including TechCrunch, so I'm not an advocate of eliminating it or blocking it altogether. But bad advertising experiences can spoil a perfectly good app like (for the purposes of argument) Messenger. Messaging is a personal, purposeful use case and these ads are a bad way to monetize it." == Reception == In November 2014, the Electronic Frontier Foundation (EFF) listed Messenger (Facebook chat) on its Secure Messaging Scorecard. It received a score of 2 out of 7 points on the scorecard. It received points for having communications encrypted in transit and for having recently completed an independent security audit. It missed points because the communications were not encrypted with keys the provider didn't have access to, users could not verify contacts' identities, past messages were not secure if the encryption keys were stolen, the source code was not open to independent review, and the security design was not properly documented. As stated by Facebook in its Help Center, there is no way to log out of the Messenger application. Instead, users can choose between different availability statuses, including "Appear as inactive", "S

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  • VoxForge

    VoxForge

    VoxForge is a free speech corpus and acoustic model repository for open source speech recognition engines. VoxForge was set up to collect transcribed speech to create a free GPL speech corpus in order to be uses with open source speech recognition engines. The speech audio files will be 'compiled' into acoustic models for use with open source speech recognition engines such as Julius, ISIP, and Sphinx and HTK (note: HTK has distribution restrictions). VoxForge has used LibriVox as a source of audio data since 2007.

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  • Read Along

    Read Along

    Read Along, formerly known as Bolo, is an Android language-learning app for children developed by Google for the Android operating system. The application was released on the Play Store on March 7, 2019. It features a character named Diya helping children learn to read through illustrated stories. It has the facility to learn English and Indian major languages i.e. Hindi, Bengali, Tamil, Telugu, Marathi and Urdu, as well as Spanish, Portuguese and Arabic. == Technology == The app uses text-to-speech technology, through which the character named Dia reads the story, as well as speech-to-text technology, which mechanically identifies the matches between the text and the reading of the user. The story of Chhota Bheem and Katha Kids was added in September 2019. In April 2020, a new version of the application was released. In September 2020, it added Arabic language to its language option. A web version was launched in August 2022.

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  • SGT STAR

    SGT STAR

    SGT STAR, also known as Sgt. Star or Sergeant Star, was a chatbot operated by the United States Army to answer questions about recruitment. == Background == After the September 11 attacks, traffic increased significantly to chatrooms on the U.S. Army's website, goarmy.com, increasing costs of staffing the live chatrooms. As a cost-cutting measure, the SGT STAR project was initiated as a partnership between the United States Army Accessions Command and Spectre AI, a wholly owned subsidiary of Next IT. Next IT, a Spokane, Washington-based company deploys "intelligent virtual assistants," using its software dubbed "ActiveAgent" which is a framework for functional presence engines. Testing began in 2003, and SGT STAR launched to the public in 2006. "STAR" is an acronym for "strong, trained and ready." SGT STAR was launched as a chat interface on goarmy.com, but has since been developed as a mobile application, as well as a life-size animated projection that has appeared live at public events. SGT STAR can also interact with users on Facebook. == FOIA request == In 2013, the Electronic Frontier Foundation filed a Freedom of Information Act request to learn more about SGT STAR, including input and output patterns (questions and answers), usage statistics, contracts, and privacy policies. They received these records in April 2014, after coverage from various media outlets and a tongue-in-cheek campaign to "Free Sgt. Star."

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  • Seam carving

    Seam carving

    Seam carving (or liquid rescaling) is an algorithm for content-aware image resizing, developed by Shai Avidan, of Mitsubishi Electric Research Laboratories (MERL), and Ariel Shamir, of the Interdisciplinary Center and MERL. It functions by establishing a number of seams (paths of least importance) in an image and automatically removes seams to reduce image size or inserts seams to extend it. Seam carving also allows manually defining areas in which pixels may not be modified, and features the ability to remove whole objects from photographs. The purpose of the algorithm is image retargeting, which is the problem of displaying images without distortion on media of various sizes (cell phones, projection screens) using document standards, like HTML, that already support dynamic changes in page layout and text but not images. Image Retargeting was invented by Vidya Setlur, Saeko Takage, Ramesh Raskar, Michael Gleicher and Bruce Gooch in 2005. The work by Setlur et al. won the 10-year impact award in 2015. == Seams == Seams can be either vertical or horizontal. A vertical seam is a path of pixels connected from top to bottom in an image with one pixel in each row. A horizontal seam is similar with the exception of the connection being from left to right. The importance/energy function values a pixel by measuring its contrast with its neighbor pixels. == Process == The below example describes the process of seam carving: The seams to remove depends only on the dimension (height or width) one wants to shrink. It is also possible to invert step 4 so the algorithm enlarges in one dimension by copying a low energy seam and averaging its pixels with its neighbors. === Computing seams === Computing a seam consists of finding a path of minimum energy cost from one end of the image to another. This can be done via Dijkstra's algorithm, dynamic programming, greedy algorithm or graph cuts among others. ==== Dynamic programming ==== Dynamic programming is a programming method that stores the results of sub-calculations in order to simplify calculating a more complex result. Dynamic programming can be used to compute seams. If attempting to compute a vertical seam (path) of lowest energy, for each pixel in a row we compute the energy of the current pixel plus the energy of one of the three possible pixels above it. The images below depict a DP process to compute one optimal seam. Each square represents a pixel, with the top-left value in red representing the energy value of that pixel. The value in black represents the cumulative sum of energies leading up to and including that pixel. The energy calculation is trivially parallelized for simple functions. The calculation of the DP array can also be parallelized with some interprocess communication. However, the problem of making multiple seams at the same time is harder for two reasons: the energy needs to be regenerated for each removal for correctness and simply tracing back multiple seams can form overlaps. Avidan 2007 computes all seams by removing each seam iteratively and storing an "index map" to record all the seams generated. The map holds a "nth seam" number for each pixel on the image, and can be used later for size adjustment. If one ignores both issues however, a greedy approximation for parallel seam carving is possible. To do so, one starts with the minimum-energy pixel at one end, and keep choosing the minimum energy path to the other end. The used pixels are marked so that they are not picked again. Local seams can also be computed for smaller parts of the image in parallel for a good approximation. == Issues == The algorithm may need user-provided information to reduce errors. This can consist of painting the regions which are to be preserved. With human faces it is possible to use face detection. Sometimes the algorithm, by removing a low energy seam, may end up inadvertently creating a seam of higher energy. The solution to this is to simulate a removal of a seam, and then check the energy delta to see if the energy increases (forward energy). If it does, prefer other seams instead. == Implementations == Adobe Systems acquired a non-exclusive license to seam carving technology from MERL, and implemented it as a feature in Photoshop CS4, where it is called Content Aware Scaling. As the license is non-exclusive, other popular computer graphics applications (e. g. GIMP, digiKam, and ImageMagick) as well as some stand-alone programs (e. g. iResizer) also have implementations of this technique, some of which are released as free and open source software. There also exists an implementation for webpages. == Improvements and extensions == Better energy function and application to video by introducing 2D (time+1D) seams. Faster implementation on GPU. Application of this forward energy function to static images. Multi-operator: Combine with cropping and scaling. Much faster removal of multiple seams. Removing seams through neural deformation fields to extend to continuous domains like 3D scenes. A 2010 review of eight image retargeting methods found that seam carving produced output that was ranked among the worst of the tested algorithms. It was, however, a part of one of the highest-ranking algorithms: the multi-operator extension mentioned above (combined with cropping and scaling).

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  • Single particle analysis

    Single particle analysis

    Single particle analysis is a group of related computerized image processing techniques used to analyze images from transmission electron microscopy (TEM). These methods were developed to improve and extend the information obtainable from TEM images of particulate samples, typically proteins or other large biological entities such as viruses. Individual images of stained or unstained particles are very noisy, making interpretation difficult. Combining several digitized images of similar particles together gives an image with stronger and more easily interpretable features. An extension of this technique uses single particle methods to build up a three-dimensional reconstruction of the particle. Using cryo-electron microscopy it has become possible to generate reconstructions with sub-nanometer, near-atomic resolution resolution first in the case of highly symmetric viruses, and now in smaller, asymmetric proteins as well. == Techniques == Single particle analysis can be done on both negatively stained and vitreous ice-embedded transmission electron cryomicroscopy (CryoTEM) samples. Single particle analysis methods are, in general, reliant on the sample being homogeneous, although techniques for dealing with conformational heterogeneity are being developed. Images (micrographs) are taken with an electron microscope using charged-coupled device (CCD) detectors coupled to a phosphorescent layer (in the past, they were instead collected on film and digitized using high-quality scanners). The image processing is carried out using specialized software programs, often run on multi-processor computer clusters. Depending on the sample or the desired results, various steps of two- or three-dimensional processing can be done. === Alignment and classification === Biological samples, and especially samples embedded in thin vitreous ice, are highly radiation sensitive, thus only low electron doses can be used to image the sample. This low dose, as well as variations in the metal stain used (if used) means images have high noise relative to the signal given by the particle being observed. By aligning several similar images to each other so they are in register and then averaging them, an image with higher signal-to-noise ratio can be obtained. As the noise is mostly randomly distributed and the underlying image features constant, by averaging the intensity of each pixel over several images only the constant features are reinforced. Typically, the optimal alignment (a translation and an in-plane rotation) to map one image onto another is calculated by cross-correlation. However, a micrograph often contains particles in multiple different orientations and/or conformations, and so to get more representative image averages, a method is required to group similar particle images together into multiple sets. This is normally carried out using one of several data analysis and image classification algorithms, such as multi-variate statistical analysis and hierarchical ascendant classification, or k-means clustering. Often data sets of tens of thousands of particle images are used, and to reach an optimal solution an iterative procedure of alignment and classification is used, whereby strong image averages produced by classification are used as reference images for a subsequent alignment of the whole data set. === Image filtering === Image filtering (band-pass filtering) is often used to reduce the influence of high and/or low spatial frequency information in the images, which can affect the results of the alignment and classification procedures. This is particularly useful in negative stain images. The algorithms make use of fast Fourier transforms (FFT), often employing Gaussian shaped soft-edged masks in reciprocal space to suppress certain frequency ranges. High-pass filters remove low spatial frequencies (such as ramp or gradient effects), leaving the higher frequencies intact. Low-pass filters remove high spatial frequency features and have a blurring effect on fine details. === Contrast transfer function === Due to the nature of image formation in the electron microscope, bright-field TEM images are obtained using significant underfocus. This, along with features inherent in the microscope's lens system, creates blurring of the collected images visible as a point spread function. The combined effects of the imaging conditions are known as the contrast transfer function (CTF), and can be approximated mathematically as a function in reciprocal space. Specialized image processing techniques such as phase flipping and amplitude correction / Wiener filtering can (at least partially) correct for the CTF, and allow high resolution reconstructions. === Three-dimensional reconstruction === Transmission electron microscopy images are projections of the object showing the distribution of density through the object, similar to medical X-rays. By making use of the projection-slice theorem a three-dimensional reconstruction of the object can be generated by combining many images (2D projections) of the object taken from a range of viewing angles. Proteins in vitreous ice ideally adopt a random distribution of orientations (or viewing angles), allowing a fairly isotropic reconstruction if a large number of particle images are used. This contrasts with electron tomography, where the viewing angles are limited due to the geometry of the sample/imaging set up, giving an anisotropic reconstruction. Filtered back projection is a commonly used method of generating 3D reconstructions in single particle analysis, although many alternative algorithms exist. Before a reconstruction can be made, the orientation of the object in each image needs to be estimated. Several methods have been developed to work out the relative Euler angles of each image. Some are based on common lines (common 1D projections and sinograms), others use iterative projection matching algorithms. The latter works by beginning with a simple, low resolution 3D starting model and compares the experimental images to projections of the model and creates a new 3D to bootstrap towards a solution. Methods are also available for making 3D reconstructions of helical samples (such as tobacco mosaic virus), taking advantage of the inherent helical symmetry. Both real space methods (treating sections of the helix as single particles) and reciprocal space methods (using diffraction patterns) can be used for these samples. === Tilt methods === The specimen stage of the microscope can be tilted (typically along a single axis), allowing the single particle technique known as random conical tilt. An area of the specimen is imaged at both zero and at high angle (~60-70 degrees) tilts, or in the case of the related method of orthogonal tilt reconstruction, +45 and −45 degrees. Pairs of particles corresponding to the same object at two different tilts (tilt pairs) are selected, and by following the parameters used in subsequent alignment and classification steps a three-dimensional reconstruction can be generated relatively easily. This is because the viewing angle (defined as three Euler angles) of each particle is known from the tilt geometry. 3D reconstructions from random conical tilt suffer from missing information resulting from a restricted range of orientations. Known as the missing cone (due to the shape in reciprocal space), this causes distortions in the 3D maps. However, the missing cone problem can often be overcome by combining several tilt reconstructions. Tilt methods are best suited to negatively stained samples, and can be used for particles that adsorb to the carbon support film in preferred orientations. The phenomenon known as charging or beam-induced movement makes collecting high-tilt images of samples in vitreous ice challenging. === Map visualization and fitting === Various software programs are available that allow viewing the 3D maps. These often enable the user to manually dock in protein coordinates (structures from X-ray crystallography, NMR, or a computational model such as one found in the AlphaFold Protein Structure Database) of subunits into the electron density. Several programs can also fit subunits computationally; as of the 2020s using these programs tend to produce better accuracy than manual docking because they can perform labor-intensive tasks such as: The scale of SPA-derived maps depends on knowing the pixel size (angstorms per pixel), which is not always accurate. Programs can automatically correct for this difference by using coordinate data or by using knowledge of chemical bonds. Many proteins are made up of several roughly rigid protein domains linked by flexible parts. Pre-existing coordinate data, whether experimental or computational, may not exactly match the inter-domain positioning of the cyro-EM map. Modern programs can automatically "chop" pre-existing coordinate data into individual domains and fit them in individually. For higher-resolution structures, it is pos

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  • List of video editing software

    List of video editing software

    The following is a list of video editing software. The criterion for inclusion in this list is the ability to perform non-linear video editing. Most modern transcoding software supports transcoding a portion of a video clip, which would count as cropping and trimming. However, items in this article have one of the following conditions: Can perform other non-linear video editing function such as montage or compositing Can do the trimming or cropping without transcoding == Free (libre) or open-source == The software listed in this section is either free software or open source, and may or may not be commercial. === Active and stable === === Inactive === == Proprietary (non-commercial) == The software listed in this section is proprietary, and freeware or freemium. === Active === === Discontinued === == Proprietary (commercial) == The software listed in this section is proprietary and commercial. === Active === === Discontinued ===

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  • Azure Data Lake

    Azure Data Lake

    Azure Data Lake is a scalable data storage and analytics service. The service is hosted in Azure, Microsoft's public cloud. == History == Azure Data Lake service was released on November 16, 2016. It is based on COSMOS, which is used to store and process data for applications such as Azure, AdCenter, Bing, MSN, Skype and Windows Live. COSMOS features a SQL-like query engine called SCOPE upon which U-SQL was built. == Storage == Data Lake Storage is a cloud service to store structured, semi-structured or unstructured data produced from applications including social networks, relational data, sensors, videos, web apps, mobile or desktop devices. A single account can store trillions of files where a single file can be greater than a petabyte in size. == Analytics == Data Lake Analytics is a parallel on-demand job service. The parallel processing system is based on Microsoft Dryad. Dryad can represent arbitrary Directed Acyclic Graphs (DAGs) of computation. Data Lake Analytics provides a distributed infrastructure that can dynamically allocate resources so that customers pay for only the services they use. The system uses Apache YARN, the part of Apache Hadoop which governs resource management across clusters. Data Lake Store supports any application that uses the Hadoop Distributed File System (HDFS) interface. == U-SQL == U-SQL is a query language for Data Lake Analytics parallel data transformation and processing programs. It combines SQL and C#: it is and an evolution of the declarative SQL language with native extensibility through user code written in C#. U-SQL uses C# data types and the C# expression language. == Retirement == In 2021, Microsoft announced the 2024 retirement of the original Azure Data Lake Storage, now called "Gen1". The related Azure Data Lake Analytics / U-SQL technologies are also being retired. Azure Data Lake Storage Gen2, an extension of Azure Storage, will continue. The suggested replacement technologies are Azure Synapse Analytics and Apache Spark.

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  • Perceptual robotics

    Perceptual robotics

    Perceptual robotics is an interdisciplinary science linking Robotics and Neuroscience. It investigates biologically motivated robot control strategies, concentrating on perceptual rather than cognitive processes and thereby sides with J. J. Gibson's view against the Poverty of the stimulus theory. As a working definition, the following quote from Chapter 64 by H. Bülthoff, C. Wallraven and M. Giese from The Springer Handbook of Robotics, edited by Bruno Siciliano and Oussama Khatib, published by Springer in 2007, could be used: In the following we will apply the term Perceptual Robotics to signify the design of robots based on principles that are derived from human perception on all three levels in the sense of Marr. This includes a realization in terms of specific neural circuits as well as the transfer of more abstract biologically-inspired strategies for the solution of relevant computational problems.

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  • Creately

    Creately

    Creately is a SaaS visual collaboration tool with diagramming and design capabilities designed by Cinergix. The application is mostly known for creating flowcharts, organization charts, project charts, UML diagrams, mind maps, and other business visuals. == History == The initial beta version of Creately was released by Chandika Jayasundara. Hiraash Thawfeek, Nick Foster and Charanjit Singh joined the project in the same year. Chandika Jayasundara is CEO of Cinergix. The headquarters of the company is located at Mentone, Victoria, Australia. == Features and reception == Creately provides predefined templates and diagram elements for incorporating in the projects. It provides drag and drop feature with which both predefined and custom made shapes can be included to build the desired diagram while the same workspace can be shared with multiple persons for collaboration. Some experts have reviewed the application by commenting on its lacking in accessible integration options as its downside. The company claims Creately to have integration feature with Slack, Confluence while not having the integration with Zapier and OneDrive yet. It is compatible with Google Drive and Dropbox. The software is available as both freemium and paid option.

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  • Subvocal recognition

    Subvocal recognition

    Subvocal recognition (SVR) is the process of taking subvocalization and converting the detected results to a digital output, aural or text-based. A silent speech interface is a device that allows speech communication without using the sound made when people vocalize their speech sounds. It works by the computer identifying the phonemes that an individual pronounces from nonauditory sources of information about their speech movements. These are then used to recreate the speech using speech synthesis. == Input methods == Silent speech interface systems have been created using ultrasound and optical camera input of tongue and lip movements. Electromagnetic devices are another technique for tracking tongue and lip movements. The detection of speech movements by electromyography of speech articulator muscles and the larynx is another technique. Another source of information is the vocal tract resonance signals that get transmitted through bone conduction called non-audible murmurs. They have also been created as a brain–computer interface using brain activity in the motor cortex obtained from intracortical microelectrodes. == Uses == Such devices are created as aids to those unable to create the sound phonation needed for audible speech such as after laryngectomies. Another use is for communication when speech is masked by background noise or distorted by self-contained breathing apparatus. A further practical use is where a need exists for silent communication, such as when privacy is required in a public place, or hands-free data silent transmission is needed during a military or security operation. In 2002, the Japanese company NTT DoCoMo announced it had created a silent mobile phone using electromyography and imaging of lip movement. The company stated that "the spur to developing such a phone was ridding public places of noise," adding that, "the technology is also expected to help people who have permanently lost their voice." The feasibility of using silent speech interfaces for practical communication has since then been shown. In 2019, Arnav Kapur, a researcher from the Massachusetts Institute of Technology, conducted a study known as AlterEgo. Its implementation of the silent speech interface enables direct communication between the human brain and external devices through stimulation of the speech muscles. By leveraging neural signals associated with speech and language, the AlterEgo system deciphers the user's intended words and translates them into text or commands without the need for audible speech. == Research and patents == With a grant from the U.S. Army, research into synthetic telepathy using subvocalization is taking place at the University of California, Irvine under lead scientist Mike D'Zmura. NASA's Ames Research Laboratory in Mountain View, California, under the supervision of Charles Jorgensen is conducting subvocalization research. The Brain Computer Interface R&D program at Wadsworth Center under the New York State Department of Health has confirmed the existing ability to decipher consonants and vowels from imagined speech, which allows for brain-based communication using imagined speech, however using EEGs instead of subvocalization techniques. US Patents on silent communication technologies include: US Patent 6587729 "Apparatus for audibly communicating speech using the radio frequency hearing effect", US Patent 5159703 "Silent subliminal presentation system", US Patent 6011991 "Communication system and method including brain wave analysis and/or use of brain activity", US Patent 3951134 "Apparatus and method for remotely monitoring and altering brain waves". Latter two rely on brain wave analysis. == In fiction == The decoding of silent speech using a computer played an important role in Arthur C. Clarke's story and Stanley Kubrick's associated film A Space Odyssey. In this, HAL 9000, a computer controlling spaceship Discovery One, bound for Jupiter, discovers a plot to deactivate it by the mission astronauts Dave Bowman and Frank Poole through lip reading their conversations. In Orson Scott Card's series (including Ender's Game), the artificial intelligence can be spoken to while the protagonist wears a movement sensor in his jaw, enabling him to converse with the AI without making noise. He also wears an ear implant. In Speaker for the Dead and subsequent novels, author Orson Scott Card described an ear implant, called a "jewel", that allows subvocal communication with computer systems. Author Robert J. Sawyer made use of subvocal recognition to allow silent commands to the cybernetic 'companion implants' used by the advanced Neanderthal characters in his Neanderthal Parallax trilogy of science fiction novels. In Earth, David Brin depicts this technology and its uses as a normal gear in the near future. In Down and Out in the Magic Kingdom, Cory Doctorow has cellphone technology become silent through a cochlear implant and miking the throat to pick up subvocalization. William Gibson's Sprawl Trilogy frequently uses sub-vocalization systems in various devices. In Kage Baker's Company novels, the immortal cyborgs communicate subvocally. In the Hugo Award-winning Hyperion Cantos by Dan Simmons, the characters often use subvocalization to communicate. In the Culture novels by Iain M. Banks, more highly advanced species often communicate subvocally through their technology. In Deus Ex: Human Revolution (2011), the protagonist is augmented with a subvocalization implant for sending covert communications (and a corresponding cochlear implant for receiving covert communications). In the tabletop RPG and video game series Shadowrun, player characters can communicate via subvocal microphones in some instances. In Paranoia, all citizens can speak to the computer via their "cerebral cortech" implants. Alistair Reynolds Revelation Space trilogy frequently uses sub-vocalization systems in various devices.

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  • EffectsLab Pro

    EffectsLab Pro

    EffectsLab Pro is a discontinued visual effects software product developed by FXhome. It has since been superseded by the FXhome HitFilm range. The company also produced a limited functionality version, EffectsLab Lite, containing just the Particle engine. A more extensive product, VisionLab Studio, combined the functionality of EffectsLab Pro and the company's CompositeLab Pro product with enhancements to both. == Effects Engines == The effects are generated by the program's effect engines: The Neon Light engine allows light beams to be drawn onto the video, allowing the generation of lightsaber-like weapons, neon lighting, fantasy glow effects and laser blasts. The Particle engine is used for particle effects, such as smoke, fire, explosions, and weather effects. The Muzzle Flash engine is designed for creating and animating muzzle flashes such as machine gun firing, tank blasts, etc. It's possible to rotate the created muzzle flash in 3D, making it the only engine with 3D use. The Optics engine is designed for creating artificial lens flares and light sources. It is useful for enhancing other light-based effects, and mimicking the distinctive flashes of light that accompany Star Wars' lightsaber battles. The Laser engine (introduced in EffectsLab Pro in late 2007) is designed as a simplified method of creating laser weapon effects, including the ability to add simulated perspective to the effect. == Presets == EffectsLab Pro allows the user to save the effects using presets. Since all effects are generated from settings in the different engines, it is fairly easy to generate an XML style description of the effect. It is also possible to share presets on FXhome's website.

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  • Computer appliance

    Computer appliance

    A computer appliance is a computer system with a combination of hardware, software, or firmware that is specifically designed to provide a particular computing resource. Such devices became known as appliances because of the similarity in role or management to a home appliance, which are generally closed and sealed, and are not serviceable by the user or owner. The hardware and software are delivered as an integrated product and may even be pre-configured before delivery to a customer, to provide a turn-key solution for a particular application. Unlike general purpose computers, appliances are generally not designed to allow the customers to change the software and the underlying operating system, or to flexibly reconfigure the hardware. Another form of appliance is the virtual appliance, which has similar functionality to a dedicated hardware appliance, but is distributed as a software virtual machine image for a hypervisor-equipped device. == Overview == Traditionally, software applications run on top of a general-purpose operating system, which uses the hardware resources of the computer (primarily memory, disk storage, processing power, and networking bandwidth) to meet the computing needs of the user. The main issue with the traditional model is related to complexity. It is complex to integrate the operating system and applications with a hardware platform, and complex to support it afterwards. By tightly constraining the variations of the hardware and software, the appliance becomes easily deployable, and can be used without nearly as wide (or deep) IT knowledge. Additionally, when problems and errors appear, the supporting staff very rarely needs to explore them deeply to understand the matter thoroughly. The staff needs merely training on the appliance management software to be able to resolve most of problems. In all forms of the computer appliance model, customers benefit from easy operations. The appliance has exactly one combination of hardware and operating system and application software, which has been pre-installed at the factory. This prevents customers from needing to perform complex integration work, and dramatically simplifies troubleshooting. In fact, this "turnkey operation" characteristic is the driving benefit that customers seek when purchasing appliances. To be considered an appliance, the (hardware) device needs to be integrated with software, and both are supplied as a package. This distinguishes appliances from "home grown" solutions, or solutions requiring complex implementations by integrators or value-added resellers (VARs). The appliance approach helps to decouple the various systems and applications, for example in the data center. Once a resource is decoupled, in theory it can be also centralized to become shared among many systems, centrally managed and optimized, all without requiring changes to any other system. == Tradeoffs of the computer appliance approach == The major disadvantage of deploying a computer appliance is that since they are designed to supply a specific resource, they most often include a customized operating system running over specialized hardware, neither of which are likely to be compatible with the other systems previously deployed. Customers lose flexibility. One may believe that a proprietary embedded operating system, or operating system within an application, can make the appliance much more secure from common cyber attacks. However, the opposite is true. Security by obscurity is a poor security decision, and appliances are often plagued by security issues as evidenced by the proliferation of IoT devices. == Types of appliances == The variety of computer appliances reflects the wide range of computing resources they provide to applications. Some examples: Storage appliances provide large amounts of storage, often available to many machines on the network. See Network-attached storage and Storage area network. Network appliances are general purpose routers which may also provide firewall protection, Transport Layer Security (TLS), messaging, access to specialized networking protocols (like the ebXML Message Service) and bandwidth multiplexing for the multiple systems they front-end. Backup and disaster recovery appliances computer appliances that are integrated backup software and backup targets, sometimes with hypervisors to support local DR of protected servers. They are often a gateway to a full DRaaS solution. Firewall and Security appliances Dedicated network appliances that are designed to protect computer networks from unwanted traffic. IIoT and MES Gateway appliances Computer appliances that are designed to translate data bidirectionally between control systems and enterprise systems. Proprietary, embedded, firmware applications running on the appliance use point-to-point connections to translate data between field devices in their native automation protocols and MES systems through their APIs, ODBC, or RESTful interfaces. Anti-spam appliances for e-mail spam Software appliances A single application server appliance, with just enough operating system (JeOS) for it to run. Virtual machine appliances consist of a "hypervisor style" embedded operating system running on appliance hardware. The hypervisor layer is matched to the hardware of the appliance, and cannot be varied by the customer, but the customer may load other operating systems and applications onto the appliance in the form of virtual machines. == Consumer appliances == Aside from its deployment within data centers, many computer appliances are directly used by the general public. These include: Digital video recorder Residential gateway Network-attached storage (NAS) Video game console Consumer uses stress the need for an appliance to have easy installation, configuration, and operation, with little or no technical knowledge being necessary. == Appliances in industrial automation == The world of industrial automation has been rich in appliances. These appliances have been hardened to withstand temperature and vibration extremes. These appliances are also highly configurable, enabling customization to meet a wide variety of applications. The key benefits of an appliance in automation are: Reduced downtime - a failed appliance is typically replaced with a COTS replacement and its task is quickly and easily reloaded from a backup. Highly scalable - appliances are typically targeted solutions for an area of a plant or process. As the requirements change, scalability is achieved through the installation of another appliance. Automation concepts are easily replicated throughout the enterprise by standardizing on appliances to perform the needed tasks, as opposed to the development of custom automation schemes for each task. Low TCO (total cost of ownership) - appliances are developed, tested and supported by automation product vendors and undergo a much broader level of quality testing than custom designed automation solutions. The use of appliances in automation reduce the level of testing needed in each individual application. Reduced design time - appliances perform specific functions and although they are highly configurable, they are typically self documenting. This enables appliance based solutions to be transferred from engineer to engineer with minimal need for training and documentation. Types of automation appliances: PLC (programmable logic controller) - Programmable logic controllers are appliances that are typically used for discrete control and offer a wide range of Input and Output options. They are configured through standardized programming languages such as IEC-1131. PID (proportional–integral–derivative controller) - PID controllers are appliances that monitor a process variable and, based on an error term, effect change on a control output (manipulated variable) to drive the process variable to a setpoint. PAC (programmable automation controller) - Programmable automation controllers are appliances that embody properties of both PLCs and PID controllers enabling the integration of both analog and discrete control. Universal gateway - A universal gateway appliance has the ability to communicate with a variety of devices through their respective communication protocols, and will affect data transactions between them. This in increasingly important as manufacturing strives to improve agility, quality, production rates, production costs and reduce downtime through enhanced M2M (machine to machine) communications. EATMs (Enterprise Appliance Transaction Modules) - Enterprise appliance transaction modules are appliances that affect data transactions from plant floor automation systems to enterprise business systems. They communicate to plant floor equipment through various vendor automation protocols, and communicate to business systems through database communication protocols such as JMS (Java Message Service) and SQL (Structured Query Language). == Internal structure == There are several

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  • VueScan

    VueScan

    VueScan is a computer program for image scanning, especially of photographs, including negatives. It supports optical character recognition (OCR) of text documents. The software can be downloaded and used free of charge, but adds a watermark on scans until a license is purchased. == Purpose == VueScan is intended to work with a large number of image scanners, excluding specialised professional scanners such as drum scanners, on many computer operating systems (OS), even if drivers for the scanner are not available for the OS. These scanners are supplied with device drivers and software to operate them, included in their price. A 2014 review considered that the reasons to purchase VueScan are to allow older scanners not supported by drivers for newer operating systems to be used in more up-to-date systems and for better scanning and processing of photographs (prints; also slides and negatives when supported by scanners) than is afforded by manufacturers' software. The review did not report any advantages to VueScan's processing of documents over other software. The reviewer considered VueScan comparable to SilverFast, a similar program, with support for some specific scanners better in one or the other. Vuescan supports more scanners, with a single purchase giving access to the full range of both film and flatbed scanners, and costs less. The VueScan program can be used with its own drivers or with drivers supplied by the scanner manufacturer, if supported by the operating system. VueScan drivers can also be used without the VueScan program by application software that supports scanning directly, such as Adobe Photoshop, again enabling the use of scanners without current manufacturers' drivers. In 2019 when Apple released macOS Catalina, they removed support for running 32-bit programs, including 32-bit drivers for scanning equipment. In response, Hamrick released VueScan 9.7, effectively saving thousands of scanners from being rendered obsolete. == Overview == VueScan enables the user to modify and fine-tune the scanning parameters. The program uses its own independent method to interface with scanner hardware, and can support many older scanners under computer operating systems for which drivers are not available, allowing old scanners to be used with newer platforms that do not otherwise support them. VueScan supports an increasing number of scanners and digital cameras; 2,400 on Windows, 2,100 on Mac OS X and 1,900 on Linux in 2018. VueScan is supplied as one downloadable file for each operating system, which supports the full range of scanners. Without the purchase of a license, the program runs in fully functional demonstration mode, identical to Professional mode, except that watermarks are superimposed on saved and printed images. Purchase of a license removes the watermark. A standard license allows updates for one year; a professional license allows unlimited updates and provides some additional features. VueScan supports optical character recognition (OCR), with English included, and 32 additional language packages available on its website. In September 2011, VueScan co-developer Ed Hamrick said that he was selling US$3 million per year of VueScan licenses.

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