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  • Non-human

    Non-human

    Non-human (also spelled nonhuman) is any entity displaying some, but not enough, human characteristics to be considered a human. The term has been used in a variety of contexts and may refer to objects that have been developed with human intelligence, such as robots or vehicles. == Organisms == === Animal rights and personhood === In the animal rights movement, it is common to distinguish between "human animals" and "non-human animals". Participants in the animal rights movement generally recognize that non-human animals have some similar characteristics to those of human persons. For example, various non-human animals have been shown to register pain, compassion, memory, and some cognitive function. Some animal rights activists argue that the similarities between human and non-human animals justify giving non-human animals rights that human society has afforded to humans, such as the right to self-preservation, and some even wish for all non-human animals or at least those that bear a fully thinking and conscious mind, such as vertebrates and some invertebrates such as cephalopods, to be given a full right of personhood. === The non-human in philosophy === Contemporary philosophers have drawn on the work of Henri Bergson, Gilles Deleuze, Félix Guattari, and Claude Lévi-Strauss (among others) to suggest that the non-human poses epistemological and ontological problems for humanist and post-humanist ethics, and have linked the study of non-humans to materialist and ethological approaches to the study of society and culture. == Software and robots == The term non-human has been used to describe computer programs and robot-like devices that display some human-like characteristics. In both science fiction and in the real world, computer programs and robots have been built to perform tasks that require human-computer interactions in a manner that suggests sentience and compassion. There is increasing interest in the use of robots in nursing homes and to provide elder care. Computer programs have been used for years in schools to provide one-on-one education with children. The Tamagotchi toy required children to provide care, attention, and nourishment to keep it "alive".

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  • Semantic heterogeneity

    Semantic heterogeneity

    Semantic heterogeneity is when database schema or datasets for the same domain are developed by independent parties, resulting in differences in meaning and interpretation of data values. Beyond structured data, the problem of semantic heterogeneity is compounded due to the flexibility of semi-structured data and various tagging methods applied to documents or unstructured data. Semantic heterogeneity is one of the more important sources of differences in heterogeneous datasets. Yet, for multiple data sources to interoperate with one another, it is essential to reconcile these semantic differences. Decomposing the various sources of semantic heterogeneities provides a basis for understanding how to map and transform data to overcome these differences. == Classification == One of the first known classification schemes applied to data semantics is from William Kent in the late 80s. Kent's approach dealt more with structural mapping issues than differences in meaning, which he pointed to data dictionaries as potentially solving. One of the most comprehensive classifications is from Pluempitiwiriyawej and Hammer, "Classification Scheme for Semantic and Schematic Heterogeneities in XML Data Sources". They classify heterogeneities into three broad classes: Structural conflicts arise when the schema of the sources representing related or overlapping data exhibit discrepancies. Structural conflicts can be detected when comparing the underlying schema. The class of structural conflicts includes generalization conflicts, aggregation conflicts, internal path discrepancy, missing items, element ordering, constraint and type mismatch, and naming conflicts between the element types and attribute names. Domain conflicts arise when the semantics of the data sources that will be integrated exhibit discrepancies. Domain conflicts can be detected by looking at the information contained in the schema and using knowledge about the underlying data domains. The class of domain conflicts includes schematic discrepancy, scale or unit, precision, and data representation conflicts. Data conflicts refer to discrepancies among similar or related data values across multiple sources. Data conflicts can only be detected by comparing the underlying sources. The class of data conflicts includes ID-value, missing data, incorrect spelling, and naming conflicts between the element contents and the attribute values. Moreover, mismatches or conflicts can occur between set elements (a "population" mismatch) or attributes (a "description" mismatch). Michael Bergman expanded upon this schema by adding a fourth major explicit category of language, and also added some examples of each kind of semantic heterogeneity, resulting in about 40 distinct potential categories . This table shows the combined 40 possible sources of semantic heterogeneities across sources: A different approach toward classifying semantics and integration approaches is taken by Sheth et al. Under their concept, they split semantics into three forms: implicit, formal and powerful. Implicit semantics are what is either largely present or can easily be extracted; formal languages, though relatively scarce, occur in the form of ontologies or other description logics; and powerful (soft) semantics are fuzzy and not limited to rigid set-based assignments. Sheth et al.'s main point is that first-order logic (FOL) or description logic is inadequate alone to properly capture the needed semantics. == Relevant applications == Besides data interoperability, relevant areas in information technology that depend on reconciling semantic heterogeneities include data mapping, semantic integration, and enterprise information integration, among many others. From the conceptual to actual data, there are differences in perspective, vocabularies, measures and conventions once any two data sources are brought together. Explicit attention to these semantic heterogeneities is one means to get the information to integrate or interoperate. A mere twenty years ago, information technology systems expressed and stored data in a multitude of formats and systems. The Internet and Web protocols have done much to overcome these sources of differences. While there is a large number of categories of semantic heterogeneity, these categories are also patterned and can be anticipated and corrected. These patterned sources inform what kind of work must be done to overcome semantic differences where they still reside.

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  • Artificial intelligence industry in Canada

    Artificial intelligence industry in Canada

    The artificial intelligence industry in Canada is a rapidly expanding sector. Although Canada held a pioneering role in the early development of artificial intelligence, transforming research excellence into broad commercial adoption has proven challenging. Despite globally recognized scientific achievements and a deep pool of skilled experts, by June 2024, Canada recorded the lowest rate of AI integration among OECD countries, with only 12% of firms implementing AI in their products or services. However, AI adoption has shown significant momentum—doubling from mid-2024 to mid-2025, rising from 6.1% to 12.2%. As of September 2025, Statistics Canada indicated that while about one-third of Canadian businesses had no plans to adopt artificial intelligence in the next year, 14.5% reported intentions to begin using AI for producing goods or delivering services. The primary reasons for not moving forward with AI were lack of relevance, insufficient knowledge, and privacy concerns. According to Public Works Canada (PwC), the pace of AI adoption in Canada is roughly three-quarters of the United States rate, highlighting a notable gap between the two countries in business integration of this technology. British-Canadian computer scientist Geoffrey Hinton stated in 2025 that Canadian companies are adopting artificial intelligence at a slower pace, which may result in the loss of the country's early advantages in the field. At the "All In AI" conference held in Montreal in September 2025, the Minister of Artificial Intelligence and Digital Innovation Evan Solomon, described "Building digital sovereignty" as the most pressing democratic issue of the time. He introduced a 26-person task force focused on updating Canada's AI strategy. In their 2024 report " "Learning Together for Responsible Artificial Intelligence" report, the Innovation, Science, and Economic Development Canada stressed that public awareness, trust, and AI literacy are essential for the responsible adoption and governance of AI in Canada. Montreal workshops in 2021 expanded the OECD's 2019 definition of AI as "the set of computer techniques that enable a machine (e.g., a computer or telephone) to perform tasks that typically require intelligence, such as reasoning or learning. It is also referred to as the automation of intelligent tasks. Scientific developments in AI, such as deep-learning techniques, have made it possible to design access to huge amounts of data and ever-increasing computing power. These new techniques have been rapidly deployed on a large scale in all areas of social life, in transport, education, culture and health." == Federal investments and policy == The 2025 federal budget allocates over $1 billion over the next five years to bolster Canada's artificial intelligence and quantum computing ecosystem. == Industry landscape or research hubs == AlexNet, an influential deep convolutional neural network developed at the University of Toronto by Alex Krizhevsky, Ilya Sutskever, and Geoffrey Hinton, marked a pivotal turning point in modern artificial intelligence. In 2012, it achieved a dramatic reduction in error rates for the ImageNet Large Scale Visual Recognition Challenge (ILSVRC), showcasing the practical power of deep learning and GPU acceleration. The success of AlexNet helped cement Canada’s reputation for AI leadership and inspired rapid adoption of deep learning across the technology sector, with ongoing impact in both academic and commercial domains. In healthcare, AlexNet has been adapted for medical imaging to assist with analyzing radiographs, mammograms, and other scans, including identifying abnormalities and supporting clinical diagnosis. In 2015, the Ottawa-based start-up Advanced Symbolics Inc. (ASI) began developing Polly, an artificial intelligence system designed to analyze and anticipate how target audiences behave—enabling more effective communication strategies and advertising campaigns. Polly was named after its first assignment analyzing the politics of Brexit. The AI gained widespread attention in 2016 for accurately forecasting both the Brexit referendum and the 2016 U.S. presidential election won by Donald Trump. The company states that Polly is used by organizations in diverse sectors—including healthcare, politics, entertainment, and mental health research—to support decision-making based on predictive analytics. Chartwatch, an AI tool developed in Canada, has been shown to reduce unexpected hospital deaths by 26% according to a 2024 study. The system analyzes patient data to detect subtle signs of deterioration, supporting healthcare teams in providing timely interventions. === Notable figures in AI in Canada === Geoffrey Hinton's decades-long work eventually formed the foundation of artificial intelligence, which earned him the Nobel Prize for physics in 2024. Yoshua Bengio, who won the Turing Award in 2018 for his pioneering work in deep learning, founded what would become Mila in 1993. Mila, is currently a collaboration between four Montreal-based academic partners.—the Pan-Canadian Artificial Intelligence Strategy includes Alberta's Amii, Toronto's Vector Institute, and Mila. Fakhreddine Karray's work on operational AI has had tangible impact across several Canadian-relevant sectors, notably intelligent transportation systems, virtual healthcare, and driver safety. === AI in the oil and gas industry === According to a 2020 Ernst & Young report the oil and gas industry in Canada is using AI in automating routine, repetitive, and dangerous tasks with technologies like robotic process automation and machine learning; optimizing production and processing; enhancing transportation logistics; improving equipment operation and monitoring; and enabling preventative maintenance. AI is also deployed for data analysis to improve prediction and decision-making, and is expected to automate up to 50% of job competencies in upstream oil and gas by 2040. Oilsands giant Suncor Energy operates a large fleet of autonomous trucks and has started using AI in its dispatch system at the Mildred Lake mine. As of 2024, AI manages routine tasks such as allocating trucks to dump stations and sending them to refuelling locations. === Indigenous and Inuit Innovation in AI === Indigenous organizations have been working on the creation of new technologies for language revitalization in partnership with National Research Council of Canada since the mid-2010s. In 2025, Inuit researchers and technology partners launched an AI-powered initiative to support the revitalization and preservation of Inuktitut, demonstrating how artificial intelligence can be adapted for Indigenous language and cultural priorities. A 2025 CBC article notes that, while AI can help revitalize Inuktitut, Inuit leaders emphasize concerns about data sovereignty, information ownership, and the need for Indigenous leadership to ensure transparency, privacy, and accountability in AI development. == Regulation == Canada's Artificial Intelligence and Data Act (AIDA) was proposed in November 2022, as part of the Digital Charter Implementation Act (Bill C-27). As well voluntary codes, such as the September 2023 Code of Conduct for Generative AI, and landmark investments in advanced computing infrastructure and the Canadian Artificial Intelligence Safety Institute (CAISI) reflect Canada's commitment to both safety and global competitiveness. == AI infrastructure == Canada has undertaken efforts to expand its AI computing infrastructure at both provincial and federal levels. The federal government's Canadian Sovereign AI Compute Strategy, allocated up to C$2 billion in Budget 2024, aims to enhance computing capacity to support domestic AI industry growth and AI adoption across the economy, with up to C$700 million designated to mobilize private sector investment in new or expanded data centres. Alberta has introduced an AI Data Centres Strategy to position itself as a leading North American destination for data centre investment, targeting C$100 billion worth of AI data centres under development by 2030. One major project under Alberta's strategy is the Wonder Valley AI Data Centre Park near Grande Prairie, which was exempted from provincial environmental impact assessment in April 2026 but still requires permits demonstrating safe construction and operation. According to Statista, as of April 2026, Canada has 287 data centres.

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  • Knuth–Eve algorithm

    Knuth–Eve algorithm

    In computer science, the Knuth–Eve algorithm is an algorithm for polynomial evaluation. It preprocesses the coefficients of the polynomial to reduce the number of multiplications required at runtime. Ideas used in the algorithm were originally proposed by Donald Knuth in 1962. His procedure opportunistically exploits structure in the polynomial being evaluated. In 1964, James Eve determined for which polynomials this structure exists, and gave a simple method of "preconditioning" polynomials (explained below) to endow them with that structure. == Algorithm == === Preliminaries === Consider an arbitrary polynomial p ∈ R [ x ] {\displaystyle p\in \mathbb {R} [x]} of degree n {\displaystyle n} . Assume that n ≥ 3 {\displaystyle n\geq 3} . Define m {\displaystyle m} such that: if n {\displaystyle n} is odd then n = 2 m + 1 {\displaystyle n=2m+1} , and if n {\displaystyle n} is even then n = 2 m + 2 {\displaystyle n=2m+2} . Unless otherwise stated, all variables in this article represent either real numbers or univariate polynomials with real coefficients. All operations in this article are done over R {\displaystyle \mathbb {R} } . Again, the goal is to create an algorithm that returns p ( x ) {\displaystyle p(x)} given any x {\displaystyle x} . The algorithm is allowed to depend on the polynomial p {\displaystyle p} itself, since its coefficients are known in advance. === Overview === ==== Key idea ==== Using polynomial long division, we can write p ( x ) = q ( x ) ⋅ ( x 2 − α ) + ( β x + γ ) , {\displaystyle p(x)=q(x)\cdot (x^{2}-\alpha )+(\beta x+\gamma ),} where x 2 − α {\displaystyle x^{2}-\alpha } is the divisor. Picking a value for α {\displaystyle \alpha } fixes both the quotient q {\displaystyle q} and the coefficients in the remainder β {\displaystyle \beta } and γ {\displaystyle \gamma } . The key idea is to cleverly choose α {\displaystyle \alpha } such that β = 0 {\displaystyle \beta =0} , so that p ( x ) = q ( x ) ⋅ ( x 2 − α ) + γ . {\displaystyle p(x)=q(x)\cdot (x^{2}-\alpha )+\gamma .} This way, no operations are needed to compute the remainder polynomial, since it's just a constant. We apply this procedure recursively to q {\displaystyle q} , expressing p ( x ) = ( ( q ( x ) ⋅ ( x 2 − α m ) + γ m ) ⋯ ) ⋅ ( x 2 − α 1 ) + γ 1 . {\displaystyle p(x)=\left(\left(q(x)\cdot (x^{2}-\alpha _{m})+\gamma _{m}\right)\cdots \right)\cdot (x^{2}-\alpha _{1})+\gamma _{1}.} After m {\displaystyle m} recursive calls, the quotient q {\displaystyle q} is either a linear or a quadratic polynomial. In this base case, the polynomial can be evaluated with (say) Horner's method. ==== "Preconditioning" ==== For arbitrary p {\displaystyle p} , it may not be possible to force β = 0 {\displaystyle \beta =0} at every step of the recursion. Consider the polynomials p e {\displaystyle p^{e}} and p o {\displaystyle p^{o}} with coefficients taken from the even and odd terms of p {\displaystyle p} respectively, so that p ( x ) = p e ( x 2 ) + x ⋅ p o ( x 2 ) . {\displaystyle p(x)=p^{e}(x^{2})+x\cdot p^{o}(x^{2}).} If every root of p o {\displaystyle p^{o}} is real, then it is possible to write p {\displaystyle p} in the form given above. Each α i {\displaystyle \alpha _{i}} is a different root of p o {\displaystyle p^{o}} , counting multiple roots as distinct. Furthermore, if at least n − 1 {\displaystyle n-1} roots of p {\displaystyle p} lie in one half of the complex plane, then every root of p o {\displaystyle p^{o}} is real. Ultimately, it may be necessary to "precondition" p {\displaystyle p} by shifting it — by setting p ( x ) ← p ( x + t ) {\displaystyle p(x)\gets p(x+t)} for some t {\displaystyle t} — to endow it with the structure that most of its roots lie in one half of the complex plane. At runtime, this shift has to be "undone" by first setting x ← x − t {\displaystyle x\gets x-t} . === Preprocessing step === The following algorithm is run once for a given polynomial p {\displaystyle p} . At this point, the values of x {\displaystyle x} that p {\displaystyle p} will be evaluated on are not known. ==== Better choice of t ==== While any t ≥ Re ( r 2 ) {\displaystyle t\geq {\text{Re}}(r_{2})} can work, it is possible to remove one addition during evaluation if t {\displaystyle t} is also chosen such that two roots of p ( x + t ) {\displaystyle p(x+t)} are symmetric about the origin. In that case, α 1 {\displaystyle \alpha _{1}} can be chosen such that the shifted polynomial has a factor of x 2 − α 1 {\displaystyle x^{2}-\alpha _{1}} , so γ 1 = 0 {\displaystyle \gamma _{1}=0} . It is always possible to find such a t {\displaystyle t} . One possible algorithm for choosing t {\displaystyle t} is: === Evaluation step === The following algorithm evaluates p {\displaystyle p} at some, now known, point x {\displaystyle x} . Assuming t {\displaystyle t} is chosen optimally, γ 1 = 0 {\displaystyle \gamma _{1}=0} . So, the final iteration of the loop can instead run y ← y ⋅ ( s − α i ) , {\displaystyle y\gets y\cdot (s-\alpha _{i}),} saving an addition. == Analysis == In total, evaluation using the Knuth–Eve algorithm for a polynomial of degree n {\displaystyle n} requires n {\displaystyle n} additions and ⌊ n / 2 ⌋ + 2 {\displaystyle \lfloor n/2\rfloor +2} multiplications, assuming t {\displaystyle t} is chosen optimally. No algorithm to evaluate a given polynomial of degree n {\displaystyle n} can use fewer than n {\displaystyle n} additions or fewer than ⌈ n / 2 ⌉ {\displaystyle \lceil n/2\rceil } multiplications during evaluation. This result assumes only addition and multiplication are allowed during both preprocessing and evaluation. The Knuth–Eve algorithm is not well-conditioned.

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  • Ghana Post GPS

    Ghana Post GPS

    GhanaPostGPS is a web and smartphone application, sponsored by the government of Ghana and developed by Vokacom, to provide a digital addresses and postal codes for every 5 squared meter location in Ghana. The digital address is a composite of the postcode (region, district & area code) plus a unique address. GhanaPostGPS is the first digital addressing system created by the government of Ghana. GhanaPost GPS is a mandatory requirement for obtaining the National Identification Card and other services.

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  • Energy informatics

    Energy informatics

    Energy informatics is a research field covering the use of information and communication technology to address energy utilization and management challenges. Methods used for "smart" implementations often combine IoT sensors with artificial intelligence and machine learning. Energy Informatics is founded on flow networks that are the major suppliers and consumers of energy. Their efficiency can be improved by collecting and analyzing information. == Application areas == The field among other consider application areas within: Smart Buildings by developing ICT-centred solutions for improving the energy-efficiency of buildings. Smart Cities by investigating the synergies between demand patterns and supply availability of energy flows in cities and communities to improve energy efficiency, increase integration of renewable sources, and provide resilience towards system faults caused by extreme situations, like hurricanes and flooding. Smart Industries including the development of ICT-centred solutions for improving the energy efficiency and predictability of energy intensive industrial processes, without compromising process and product quality. Smart Energy Networks by developing ICT-centred solutions for coordinating the supply and demand in environmentally sustainable energy networks.

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  • Information professional

    Information professional

    The term information professional or information specialist refers to professionals responsible for the collection, documentation, organization, storage, preservation, retrieval, and dissemination of printed and digital information. The service delivered to the client is known as an information service. The term "information professional" is a versatile one, used to describe similar and sometimes overlapping professions, such as librarians, archivists, information managers, information systems specialists, information scientists, records managers, and information consultants. However, terminology differs among sources and organisations. Information professionals are employed in a variety of private, public, and academic institutions, as well as independently. == Skills == Since the term information professional is broad, the skills required for this profession are also varied. A Gartner report in 2011 pointed out that "Professional roles focused on information management will be different to that of established IT roles. An 'information professional' will not be one type of role or skill set, but will in fact have a number of specializations". Thus, an information professional can possess a variety of different skills, depending on the sector in which the person is employed. Some essential cross-sector skills are: IT skills, such as word-processing and spreadsheets, digitisation skills, and conducting Internet searches, together with skills loan systems, databases, content management systems, and specially designed programmes and packages. Customer service. An information professional should have the ability to address the information needs of customers. Language proficiency. This is essential in order to manage the information at hand and deal with customer needs. Soft skills. These include skills such as negotiating, conflict resolution, and time management. Management training. An information professional should be familiar with notions such as strategic planning and project management. Moreover, an information professional should be skilled in planning and using relevant systems, in capturing and securing information, and in accessing it to deliver service whenever the information is required. == Associations == Most countries have a professional association who oversee the professional and academic standards of librarians and other information professionals. There are also international associations related to LIS (library and information science), the most prominent of which is the International Federation of Library Associations and Institutions (IFLA). In many countries, LIS courses are accredited by the relevant professional association, as the American Library Association (ALA) in the USA, the Chartered Institute of Library and Information Professionals (CILIP) in the UK, and the Australian Library and Information Association (ALIA) in Australia. == Qualifications == Educational institutions around the world offer academic degrees, or degrees on related subjects such as Archival Studies, Information Systems, Information Management, and Records Management. Some of the institutions offering information science education refer to themselves as an iSchool, such as the CiSAP (Consortium of iSchools Asia Pacific, founded 2006) in Asia and the iSchool Caucus in the USA. There are also online e-learning resources, some of which offer certification for information professionals. === Africa === Information development in Africa started later than in other continents, mainly due to a lack of internet access, expertise and resources to manage digital infrastructure, and "opportunities for capacity development and knowledge-sharing". Nowadays, academic degrees in information studies are available at many universities of African countries, such as the University of Pretoria (South Africa), University of Nairobi (Kenya), Makerere University (Uganda), University of Botswana (Botswana), and University of Nigeria (Nigeria). === Asia === LIS-related studies are available in more than 30 Asian countries. Some examples listed by iSchools Inc. are the University of Hong Kong, University of Tsukuba, Japan, Yonsei University, South Korea, National Taiwan University and Wuhan University, China. Centre of Library and Information Management Science (CLIMS) at Tata Institute of Social Science in Mumbai, India. In Southeast Asia, the Congress of Southeast Asian Librarians (CONSAL) connects librarians and libraries in more than 10 countries with resources, networking opportunities, and support for growing library systems. === Australasia === The Australian Library and Information Association (ALIA) as of 2021 lists six schools offering undergraduate and postgraduate accredited university courses for "Librarian and Information Specialists" on their website. In New Zealand, the Open Polytechnic of New Zealand and the Victoria University of Wellington offer undergraduate and postgraduate degree courses for information professionals. === Europe === The majority of European countries have universities, colleges, or schools which offer bachelor's degrees in LIS studies. Over 40 universities offer master's degrees in LIS-related fields, and many institutions, such as the Swedish School of Library and Information Science at the University of Borås (Sweden), the University of Barcelona (Spain), Loughborough University (UK), and Aberystwyth University (Wales, UK) also offer PhD degrees. === North America === Information studies and degrees are available at numerous academic institutions throughout the U.S. and Canada. U.S. professional associations, together with their European counterparts, have undertaken many educational initiatives and pioneered many advances in the field of Information studies, such as increased interdisciplinarity and more effective delivery of distance learning. The Association for Intelligent Information Management, based in Silver Spring, Maryland, offers a qualification called Certified Information Professional (CIP), earned upon passing an examination, with certification remaining valid for three years. === South America === There are many schools and colleges in Latin America, which offer courses in Library Science, Archival Studies, and Information Studies, however these subjects are taught completely separately.

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  • Berlekamp–Rabin algorithm

    Berlekamp–Rabin algorithm

    In number theory, Berlekamp's root finding algorithm, also called the Berlekamp–Rabin algorithm, is the probabilistic method of finding roots of polynomials over the field F p {\displaystyle \mathbb {F} _{p}} with p {\displaystyle p} elements. The method was discovered by Elwyn Berlekamp in 1970 as an auxiliary to the algorithm for polynomial factorization over finite fields. The algorithm was later modified by Rabin for arbitrary finite fields in 1979. The method was also independently discovered before Berlekamp by other researchers. == History == The method was proposed by Elwyn Berlekamp in his 1970 work on polynomial factorization over finite fields. His original work lacked a formal correctness proof and was later refined and modified for arbitrary finite fields by Michael Rabin. In 1986 René Peralta proposed a similar algorithm for finding square roots in F p {\displaystyle \mathbb {F} _{p}} . In 2000 Peralta's method was generalized for cubic equations. == Statement of problem == Let p {\displaystyle p} be an odd prime number. Consider the polynomial f ( x ) = a 0 + a 1 x + ⋯ + a n x n {\textstyle f(x)=a_{0}+a_{1}x+\cdots +a_{n}x^{n}} over the field F p ≃ Z / p Z {\displaystyle \mathbb {F} _{p}\simeq \mathbb {Z} /p\mathbb {Z} } of remainders modulo p {\displaystyle p} . The algorithm should find all λ {\displaystyle \lambda } in F p {\displaystyle \mathbb {F} _{p}} such that f ( λ ) = 0 {\textstyle f(\lambda )=0} in F p {\displaystyle \mathbb {F} _{p}} . == Algorithm == === Randomization === Let f ( x ) = ( x − λ 1 ) ( x − λ 2 ) ⋯ ( x − λ n ) {\textstyle f(x)=(x-\lambda _{1})(x-\lambda _{2})\cdots (x-\lambda _{n})} . Finding all roots of this polynomial is equivalent to finding its factorization into linear factors. To find such factorization it is sufficient to split the polynomial into any two non-trivial divisors and factorize them recursively. To do this, consider the polynomial f z ( x ) = f ( x − z ) = ( x − λ 1 − z ) ( x − λ 2 − z ) ⋯ ( x − λ n − z ) {\textstyle f_{z}(x)=f(x-z)=(x-\lambda _{1}-z)(x-\lambda _{2}-z)\cdots (x-\lambda _{n}-z)} where z {\displaystyle z} is some element of F p {\displaystyle \mathbb {F} _{p}} . If one can represent this polynomial as the product f z ( x ) = p 0 ( x ) p 1 ( x ) {\displaystyle f_{z}(x)=p_{0}(x)p_{1}(x)} then in terms of the initial polynomial it means that f ( x ) = p 0 ( x + z ) p 1 ( x + z ) {\displaystyle f(x)=p_{0}(x+z)p_{1}(x+z)} , which provides needed factorization of f ( x ) {\displaystyle f(x)} . === Classification of === F p {\displaystyle \mathbb {F} _{p}} elements Due to Euler's criterion, for every monomial ( x − λ ) {\displaystyle (x-\lambda )} exactly one of following properties holds: The monomial is equal to x {\displaystyle x} if λ = 0 {\displaystyle \lambda =0} , The monomial divides g 0 ( x ) = ( x ( p − 1 ) / 2 − 1 ) {\textstyle g_{0}(x)=(x^{(p-1)/2}-1)} if λ {\displaystyle \lambda } is quadratic residue modulo p {\displaystyle p} , The monomial divides g 1 ( x ) = ( x ( p − 1 ) / 2 + 1 ) {\textstyle g_{1}(x)=(x^{(p-1)/2}+1)} if λ {\displaystyle \lambda } is quadratic non-residual modulo p {\displaystyle p} . Thus if f z ( x ) {\displaystyle f_{z}(x)} is not divisible by x {\displaystyle x} , which may be checked separately, then f z ( x ) {\displaystyle f_{z}(x)} is equal to the product of greatest common divisors gcd ( f z ( x ) ; g 0 ( x ) ) {\displaystyle \gcd(f_{z}(x);g_{0}(x))} and gcd ( f z ( x ) ; g 1 ( x ) ) {\displaystyle \gcd(f_{z}(x);g_{1}(x))} . === Berlekamp's method === The property above leads to the following algorithm: Explicitly calculate coefficients of f z ( x ) = f ( x − z ) {\displaystyle f_{z}(x)=f(x-z)} , Calculate remainders of x , x 2 , x 2 2 , x 2 3 , x 2 4 , … , x 2 ⌊ log 2 ⁡ p ⌋ {\textstyle x,x^{2},x^{2^{2}},x^{2^{3}},x^{2^{4}},\ldots ,x^{2^{\lfloor \log _{2}p\rfloor }}} modulo f z ( x ) {\displaystyle f_{z}(x)} by squaring the current polynomial and taking remainder modulo f z ( x ) {\displaystyle f_{z}(x)} , Using exponentiation by squaring and polynomials calculated on the previous steps calculate the remainder of x ( p − 1 ) / 2 {\textstyle x^{(p-1)/2}} modulo f z ( x ) {\textstyle f_{z}(x)} , If x ( p − 1 ) / 2 ≢ ± 1 ( mod f z ( x ) ) {\textstyle x^{(p-1)/2}\not \equiv \pm 1{\pmod {f_{z}(x)}}} then gcd {\displaystyle \gcd } mentioned below provide a non-trivial factorization of f z ( x ) {\displaystyle f_{z}(x)} , Otherwise all roots of f z ( x ) {\displaystyle f_{z}(x)} are either residues or non-residues simultaneously and one has to choose another z {\displaystyle z} . If f ( x ) {\displaystyle f(x)} is divisible by some non-linear primitive polynomial g ( x ) {\displaystyle g(x)} over F p {\displaystyle \mathbb {F} _{p}} then when calculating gcd {\displaystyle \gcd } with g 0 ( x ) {\displaystyle g_{0}(x)} and g 1 ( x ) {\displaystyle g_{1}(x)} one will obtain a non-trivial factorization of f z ( x ) / g z ( x ) {\displaystyle f_{z}(x)/g_{z}(x)} , thus algorithm allows to find all roots of arbitrary polynomials over F p {\displaystyle \mathbb {F} _{p}} . === Modular square root === Consider equation x 2 ≡ a ( mod p ) {\textstyle x^{2}\equiv a{\pmod {p}}} having elements β {\displaystyle \beta } and − β {\displaystyle -\beta } as its roots. Solution of this equation is equivalent to factorization of polynomial f ( x ) = x 2 − a = ( x − β ) ( x + β ) {\textstyle f(x)=x^{2}-a=(x-\beta )(x+\beta )} over F p {\displaystyle \mathbb {F} _{p}} . In this particular case problem it is sufficient to calculate only gcd ( f z ( x ) ; g 0 ( x ) ) {\displaystyle \gcd(f_{z}(x);g_{0}(x))} . For this polynomial exactly one of the following properties will hold: GCD is equal to 1 {\displaystyle 1} which means that z + β {\displaystyle z+\beta } and z − β {\displaystyle z-\beta } are both quadratic non-residues, GCD is equal to f z ( x ) {\displaystyle f_{z}(x)} which means that both numbers are quadratic residues, GCD is equal to ( x − t ) {\displaystyle (x-t)} which means that exactly one of these numbers is quadratic residue. In the third case GCD is equal to either ( x − z − β ) {\displaystyle (x-z-\beta )} or ( x − z + β ) {\displaystyle (x-z+\beta )} . It allows to write the solution as β = ( t − z ) ( mod p ) {\textstyle \beta =(t-z){\pmod {p}}} . === Example === Assume we need to solve the equation x 2 ≡ 5 ( mod 11 ) {\textstyle x^{2}\equiv 5{\pmod {11}}} . For this we need to factorize f ( x ) = x 2 − 5 = ( x − β ) ( x + β ) {\displaystyle f(x)=x^{2}-5=(x-\beta )(x+\beta )} . Consider some possible values of z {\displaystyle z} : Let z = 3 {\displaystyle z=3} . Then f z ( x ) = ( x − 3 ) 2 − 5 = x 2 − 6 x + 4 {\displaystyle f_{z}(x)=(x-3)^{2}-5=x^{2}-6x+4} , thus gcd ( x 2 − 6 x + 4 ; x 5 − 1 ) = 1 {\displaystyle \gcd(x^{2}-6x+4;x^{5}-1)=1} . Both numbers 3 ± β {\displaystyle 3\pm \beta } are quadratic non-residues, so we need to take some other z {\displaystyle z} . Let z = 2 {\displaystyle z=2} . Then f z ( x ) = ( x − 2 ) 2 − 5 = x 2 − 4 x − 1 {\displaystyle f_{z}(x)=(x-2)^{2}-5=x^{2}-4x-1} , thus gcd ( x 2 − 4 x − 1 ; x 5 − 1 ) ≡ x − 9 ( mod 11 ) {\textstyle \gcd(x^{2}-4x-1;x^{5}-1)\equiv x-9{\pmod {11}}} . From this follows x − 9 = x − 2 − β {\textstyle x-9=x-2-\beta } , so β ≡ 7 ( mod 11 ) {\displaystyle \beta \equiv 7{\pmod {11}}} and − β ≡ − 7 ≡ 4 ( mod 11 ) {\textstyle -\beta \equiv -7\equiv 4{\pmod {11}}} . A manual check shows that, indeed, 7 2 ≡ 49 ≡ 5 ( mod 11 ) {\textstyle 7^{2}\equiv 49\equiv 5{\pmod {11}}} and 4 2 ≡ 16 ≡ 5 ( mod 11 ) {\textstyle 4^{2}\equiv 16\equiv 5{\pmod {11}}} . == Correctness proof == The algorithm finds factorization of f z ( x ) {\displaystyle f_{z}(x)} in all cases except for ones when all numbers z + λ 1 , z + λ 2 , … , z + λ n {\displaystyle z+\lambda _{1},z+\lambda _{2},\ldots ,z+\lambda _{n}} are quadratic residues or non-residues simultaneously. According to theory of cyclotomy, the probability of such an event for the case when λ 1 , … , λ n {\displaystyle \lambda _{1},\ldots ,\lambda _{n}} are all residues or non-residues simultaneously (that is, when z = 0 {\displaystyle z=0} would fail) may be estimated as 2 − k {\displaystyle 2^{-k}} where k {\displaystyle k} is the number of distinct values in λ 1 , … , λ n {\displaystyle \lambda _{1},\ldots ,\lambda _{n}} . In this way even for the worst case of k = 1 {\displaystyle k=1} and f ( x ) = ( x − λ ) n {\displaystyle f(x)=(x-\lambda )^{n}} , the probability of error may be estimated as 1 / 2 {\displaystyle 1/2} and for modular square root case error probability is at most 1 / 4 {\displaystyle 1/4} . == Complexity == Let a polynomial have degree n {\displaystyle n} . We derive the algorithm's complexity as follows: Due to the binomial theorem ( x − z ) k = ∑ i = 0 k ( k i ) ( − z ) k − i x i {\textstyle (x-z)^{k}=\sum \limits _{i=0}^{k}{\binom {k}{i}}(-z)^{k-i}x^{i}} , we may transition from f ( x ) {\displaystyle f(x)} to f ( x − z ) {\displaystyle f(x-z)} in O ( n 2 ) {\displaystyle O(n^{2})} time. Polynomial multiplication a

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  • Foundry VTT

    Foundry VTT

    Foundry Virtual Tabletop, commonly shortened to Foundry VTT or FVTT, is a commercial, self-hosted virtual tabletop application for role-playing games. It provides a stage for visualizing the game environment and tools allowing the game master and players to organize and track statistics and notes. The software is highly modular and depends on the community-maintained ecosystem of add-on modules that modify the software's behavior and implement different game systems. Perpetual licenses, which include updates, are offered for a one-time fee. == Features == Foundry Virtual Tabletop is a highly modular Node.js web application that is run locally by the Gamemaster or hosted on a remote server. Players connect to their gamemaster's Foundry VTT instance over the network using their web browser. It is system-agnostic in that its core feature-set is not restricted to a specific game system. Systems, specific features and game content are implemented as add-on modules, which can be individually downloaded from a public repository. The module repository contains paid, official content, as well as freely available community-made modules that enhance functionality of the software. As of May 2025, 350 individual game systems are implemented as modules. Individual settings created by the Game Master are termed Worlds in the interface and contain the list of modules that should be loaded as well as world-specific content, which can be added by the gamemaster. This content is grouped into Scenes, Actors, Items and Journals. Battle and world maps are created as Scenes, which contain the backdrop and data on placement of walls, light sources and other entities. Tokens representing Actors, which are player characters, vehicles or NPCs, can be placed on these Scenes to be moved by the user that owns them. Other entities that interact or integrate with actors are termed Items; these can be objects, but also game system-specific concepts such as character classes. Journals are text documents that can link to other entities present in the World or modules. Viewing and editing permissions can be set individually for each entity. The software features a custom lighting engine that determines visibility of certain areas on each battle map depending on the position of players' characters, also revealing areas covered by fog of war. It also contains tools for map creation and comes with a small asset library. == History == Foundry Gaming LLC founder Andrew Clayton, commonly known under his online nickname Atropos, began development of Foundry VTT in 2018 for personal use after becoming dissatisfied with the feature set and business models of other virtual tabletops. Foundry VTT was initially developed for Linux, which remains its primary platform, with support for other platforms having been developed later. Foundry Gaming LLC was incorporated in Spokane, Washington on October 9, 2018, with the software remaining in private beta-testing until May 2020, when it was publicly released. In November 2020, Cubicle 7 partnered with Foundry to bring official content modules for its game system Warhammer Fantasy Roleplay to Foundry VTT. Later, in 2025, Clayton would state that this first major publisher deal was of significant importance to Foundry VTT's growth and credits the community developers of the WFRP system module for making it possible in the first place. In November 2023, Paizo partnered with Foundry to bring official content modules for Pathfinder Roleplaying Game to Foundry VTT. In January 2024, Foundry publicly announced its partnership with Wizards of the Coast in bringing official Dungeons & Dragons content to Foundry VTT, with the first official module, Phandelver and Below: The Shattered Obelisk, having been released in February 2024. == Development == As of 2023, the Foundry VTT software itself is being developed and managed by a team of 9 people, while a content team of 12 people is working with partnered publishers to compile content into downloadable modules. The content team also develops in-house content published by Foundry Gaming LLC. Stated goals are to create a virtual tabletop software that offers a one-time purchase and content ownership, make use of modern web technologies, and provide a platform for developers to build upon. Clayton has stated that integration of Generative AI into Foundry VTT is not planned, citing ethical and legal concerns and calling its usage within the industry a "betrayal of the creative people who made the TTRPG industry what it is in the first place". == Reception == Foundry VTT is one of the most popular virtual tabletops for TTRPGs; in particular, as a self-hosted web-based VTT, it is known as a modern alternative to the software as a service Roll20. Wargamer named it one of the three "best virtual tabletops for D&D in 2023", noting its active community and high degree of technical complexity, which allows for customization not seen in other products at the cost of a much steeper learning curve. Comic Book Resources called it an "underrated gem" and "incredibly versatile" for similar reasons, while also praising its lighting engine and visual fidelity. As the previously mentioned outlets do, Foundry's modular ecosystem and technical implementation are often mentioned as good features, but also as a source of frustration for new users. In a video interview, Clayton acknowledges this issue and affirms that the development team intends to make usage of more technical features "friction-less" and will reduce module breakage between updates in the future.

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  • Shapiro–Senapathy algorithm

    Shapiro–Senapathy algorithm

    The Shapiro—Senapathy algorithm (S&S) is a computational method for identifying splice sites in eukaryotic genes. The algorithm employs a Position Weight Matrix (PWM) scoring formula to predict donor and acceptor splice sites in any given gene. This methodology has been used to discover splice sites and disease-causing splice site mutations in the human genome, and has become a standard tool in clinical genomics. The S&S algorithm has been cited in thousands of clinical studies, according to Google Scholar. It has also formed the basis of widely used software, including Human Splicing Finder, SROOGLE, and Alamut, which identify splice sites and splice site mutations that cause disease. The algorithm has uncovered splicing mutations in diseases ranging from cancers to inherited disorders, and predicted the deleterious effects of these mutations including exon skipping, intron retention, and cryptic splice site activation. == The algorithm == A splice site defines the boundary between a coding exon and a non-coding intron in eukaryotic genes. The S&S algorithm employs a sliding window, corresponding to the length of the splice site motif, to scan a gene sequence and detect potential splice sites. For each sliding window, the algorithm calculates a score by comparing the nucleotide sequence to a Position Weight Matrix (PWM) derived from known splice sites. This formula generates a percentile score, indicating the likelihood that a given sequence functions as a donor or acceptor splice site. The majority of disease-causing mutations in the human genome are located in splice sites. Clinical genomics studies analyze the splice site scores generated by the S&S algorithm to predict the consequences of splice site mutations including exon skipping and intron retention. The algorithm's sensitivity to single-nucleotide changes allows it to determine mutations that may impact RNA splicing and contribute to disease. In addition to identifying real splice sites, the S&S algorithm has been used to discover cryptic splice sites — alternative splice sites activated by mutations — which may disrupt normal splicing. The algorithm detects mutations that lead to the activation of cryptic splice sites, which may be located proximal to real splice sites or deep within non-coding introns. It has thus been used to determine the causes of numerous diseases that are due to cryptic splicing. == Cancer gene discovery using S&S == The S&S algorithm has been used to identify splice-site mutations in genes associated with several cancers. For example, genes causing commonly occurring cancers including breast cancer, ovarian cancer, colorectal cancer, leukemia, head and neck cancers, prostate cancer, retinoblastoma, squamous cell carcinoma, gastrointestinal cancer, melanoma, liver cancer, Lynch syndrome, skin cancer, and neurofibromatosis have been found. In addition, splicing mutations in genes causing less commonly known cancers including gastric cancer, gangliogliomas, Li-Fraumeni syndrome, Loeys–Dietz syndrome, Osteochondromas (bone tumor), Nevoid basal cell carcinoma syndrome, and Pheochromocytomas have been identified. Specific mutations in different splice sites in various genes causing breast cancer (e.g., BRCA1, PALB2), ovarian cancer (e.g., SLC9A3R1, COL7A1, HSD17B7), colon cancer (e.g., APC, MLH1, DPYD), colorectal cancer (e.g., COL3A1, APC, HLA-A), skin cancer (e.g., COL17A1, XPA, POLH), and Fanconi anemia (e.g., FANC, FANA) have been uncovered. The mutations in the donor and acceptor splice sites in different genes causing a variety of cancers that have been identified by S&S are shown in Table 1. == Discovery of genes causing inherited disorders using S&S == Specific mutations in different splice sites in various genes that cause inherited disorders, including, for example, Type 1 diabetes (e.g., PTPN22, TCF1 (HCF-1A)), hypertension (e.g., LDL, LDLR, LPL), Marfan syndrome (e.g., FBN1, TGFBR2, FBN2), cardiac diseases (e.g., COL1A2, MYBPC3, ACTC1), eye disorders (e.g., EVC, VSX1) have been uncovered. A few example mutations in the donor and acceptor splice sites in different genes causing a variety of inherited disorders identified using S&S are shown in Table 2. == Genes causing immune system disorders == More than 100 immune system disorders affect humans, including inflammatory bowel diseases, multiple sclerosis, systemic lupus erythematosus, bloom syndrome, familial cold autoinflammatory syndrome, and dyskeratosis congenita. The Shapiro–Senapathy algorithm has been used to discover genes and mutations involved in many immune disorder diseases, including Ataxia telangiectasia, B-cell defects, epidermolysis bullosa, and X-linked agammaglobulinemia. Xeroderma pigmentosum, an autosomal recessive disorder is caused by faulty proteins formed due to new preferred splice donor site identified using S&S algorithm and resulted in defective nucleotide excision repair. Type I Bartter syndrome (BS) is caused by mutations in the gene SLC12A1. S&S algorithm helped in disclosing the presence of two novel heterozygous mutations c.724 + 4A > G in intron 5 and c.2095delG in intron 16 leading to complete exon 5 skipping. Mutations in the MYH gene, which is responsible for removing the oxidatively damaged DNA lesion are cancer-susceptible in the individuals. The IVS1+5C plays a causative role in the activation of a cryptic splice donor site and the alternative splicing in intron 1, S&S algorithm shows, guanine (G) at the position of IVS+5 is well conserved (at the frequency of 84%) among primates. This also supported the fact that the G/C SNP in the conserved splice junction of the MYH gene causes the alternative splicing of intron 1 of the β type transcript. Splice site scores were calculated according to S&S to find EBV infection in X-linked lymphoproliferative disease. Identification of Familial tumoral calcinosis (FTC) is an autosomal recessive disorder characterized by ectopic calcifications and elevated serum phosphate levels and it is because of aberrant splicing. == Application of S&S in hospitals for clinical practice and research == The Shapiro–Senapathy (S&S) algorithm has played a significant role in advancing the diagnosis and treatment of human diseases through its application in modern clinical genomics. With the widespread adoption of next-generation sequencing (NGS) technologies, the S&S algorithm is now routinely integrated into clinical practice by geneticists and diagnostic laboratories. It is implemented in various computational tools such as Human Splicing Finder (HSF), Splice Site Finder (SSF), and Alamut Visual, which assist in interpreting the functional impact of genetic variants on RNA splicing. The algorithm is particularly useful in identifying pathogenic splice site mutations in cases where the clinical presentation is unclear or where conventional diagnostic methods have failed to identify a causative gene. Its utility has been demonstrated across diverse patient cohorts, including individuals from different ethnic backgrounds with various cancers and inherited genetic disorders. The following are selected examples illustrating its application in clinical research. === Cancers === === Inherited disorders === == S&S - Algorithm for identifying splice sites, exons and split genes == The Shapiro–Senapathy algorithm (SSA) was developed to identify splice sites in uncharacterized genomic sequences, with early applications in the Human Genome Project. The method introduced a Position Weight Matrix (PWM)-based approach to analyze splicing sequences across eukaryotic organisms, marking the first computational framework to systematically define splice sites using probabilistic scoring. Key innovations of the algorithm included: Exon Detection – Exons were defined as sequences bounded by acceptor and donor splice sites with S&S scores above a threshold, requiring an open reading frame (ORF) for validation. Gene Prediction – The method enabled the identification of complete genes by assembling predicted exons, forming a basis for later gene-finding tools. Mutation Analysis – The algorithm distinguishes deleterious splice-site mutations (which disrupt protein function by lowering S&S scores) from neutral variations. This capability allowed researchers to study disease-linked cryptic splice sites in humans, animals, and plants. SSA's PWM-based framework influenced subsequent computational methods, including machine learning and neural network approaches, for splice-site prediction and alternative splicing research. It remains a foundational tool in genomics and disease studies. == Discovering the mechanisms of aberrant splicing in diseases == The Shapiro–Senapathy algorithm has been used to determine the various aberrant splicing mechanisms in genes due to deleterious mutations in the splice sites, which cause numerous diseases. Deleterious splice site mutations impair the normal splicing of the gene transcripts, and thereby make the encoded protei

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  • Aidoc

    Aidoc

    Aidoc Medical is an Israeli technology company that develops computer-aided simple triage and notification systems. Aidoc has obtained U.S. Food and Drug Administration and CE mark approval for its stroke, pulmonary embolism, cervical fracture, intracranial hemorrhage, intra-abdominal free gas, and incidental pulmonary embolism algorithms. Aidoc algorithms are in use in more than 900 hospitals and imaging centers, including Montefiore Nyack Hospital, LifeBridge Health, LucidHealth, Yale New Haven Hospital, Cedars-Sinai Medical Center, University of Rochester Medical Center, and Sheba Medical Center. == History == Aidoc was founded in 2016 by Elad Walach as the CEO, Michael Braginsky as the CTO and Guy Reiner as the VP. In April 2017, the company raised $7M, led by TLV Partners, and in April 2019, the company raised another $27M, led by Square Peg capital. There have been several additional rounds of funding as well, bringing Aidoc's total investment to $370M as of July 2025. In August 2018, Aidoc gained FDA clearance for its intracranial hemorrhage system, and in May 2019 it received clearance for the pulmonary embolism system. In January 2020, the system for detecting large-vessel occlusions (LVOs) in head CTA examinations obtained FDA clearance. In October 2024, it was reported that Aidoc is working with NVIDIA to develop a framework for deployment and integration of artificial intelligence tools in healthcare. The Blueprint for Resilient Integration and Deployment of Guided Excellence (BRIDGE) is a guideline to facilitate AI adoption in the healthcare industry. == Products and market == Aidoc has developed a suite of artificial intelligence products that flag both time-sensitive and time-consuming (for the radiologist) abnormalities across the body. The algorithms are developed with large quantities of data to provide diagnostic aid for a broad set of pathologies. The company offers an array of algorithms that span across the body, including for intracranial hemorrhage, spine fractures (C, T & L), free air in the abdomen, pulmonary embolism, and more. It developed "Always-on AI", a term coined by Elad Walach that refers to a type of artificial intelligence that is "Always-on—constantly running in the background and automatically analyzing medical imaging data, identifying urgent findings, and sparing radiologists from "drowning" in vast amounts of irrelevant data. Aidoc's solutions cover medical conditions prevalent in all settings (ED/inpatient/outpatient), including level 1 trauma centers, outpatient imaging centers, teleradiology groups and, are set up in over 200 medical centers worldwide. Notable customers include the University of Rochester Medical Center and Global Diagnostics Australia. Aidoc announced in 2024 that its new Clinical AI Reasoning Engine (CARE1) had been submitted for FDA approval. In September 2025 Aidoc received a "Breakthrough Device Designation" from the FDA for a new multi-triage solution that spans numerous acute findings in CT scans. Aidoc's CARE1 foundation model was the basis of the workflow on which the designation was made, enabling simultaneous coverage of multiple pathologies. This new designation allows parallel FDA review of multiple indications under a single submission. In April 2026, Aidoc raised million in a Series E funding round led by Growth Equity at Goldman Sachs Alternatives, with participation from General Catalyst and NVentures. The financing brought the company's total funding to over million. == Clinical Research == A clinical study on Aidoc’ accuracy of deep convolutional neural networks for the detection of pulmonary embolism (PE) on CT pulmonary angiograms (CTPAs) was performed by the University Hospital of Basel and presented at the European Congress of Radiology, showing that the Aidoc algorithm reached 93% sensitivity and 95% specificity. Clinical research has also been performed to test the diagnostic performance of Aidoc's deep learning-based triage system for the flagging of acute findings in abdominal computed tomography (CT) examinations. Overall, the algorithm achieved 93% sensitivity (91/98, 7 false negatives) and 97% specificity (93/96, 3 false-positive) in the detection of acute abdominal findings. Additional clinical research on Aidoc's Intracranial hemorrhage algorithm accuracy was presented at the European Congress of Radiology by Antwerp University Hospital, evaluating the use of its deep learning algorithm for the detection of intracranial hemorrhage on non-contrast enhanced CT of the brain. The University of Washington completed a study on the accuracy of Aidoc's intracranial hemorrhage algorithm.

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  • Unrestricted algorithm

    Unrestricted algorithm

    An unrestricted algorithm is an algorithm for the computation of a mathematical function that puts no restrictions on the range of the argument or on the precision that may be demanded in the result. The idea of such an algorithm was put forward by C. W. Clenshaw and F. W. J. Olver in a paper published in 1980. In the problem of developing algorithms for computing, as regards the values of a real-valued function of a real variable (e.g., g[x] in "restricted" algorithms), the error that can be tolerated in the result is specified in advance. An interval on the real line would also be specified for values when the values of a function are to be evaluated. Different algorithms may have to be applied for evaluating functions outside the interval. An unrestricted algorithm envisages a situation in which a user may stipulate the value of x and also the precision required in g(x) quite arbitrarily. The algorithm should then produce an acceptable result without failure.

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  • Amazon Kinesis

    Amazon Kinesis

    Amazon Kinesis is a family of services provided by Amazon Web Services (AWS) for processing and analyzing real-time streaming data at a large scale. Launched in November 2013, it offers developers the ability to build applications that can consume and process data from multiple sources simultaneously. Kinesis supports multiple use cases, including real-time analytics, log and event data collection, and real-time processing of data generated by IoT devices. == History == Amazon Kinesis was launched by Amazon Web Services (AWS) in November 2013 as a managed service for processing and analyzing real-time streaming data at a large scale. The service was introduced to address the growing need for businesses to process and analyze data as it was generated, rather than in batches, allowing for real-time insights and decision-making. Since its launch, the Amazon Kinesis family of services has expanded to include four main components: Kinesis Data Streams, Kinesis Data Firehose, Kinesis Data Analytics, and Kinesis Video Streams. Each of these components serves a specific purpose in the processing and analysis of real-time streaming data. In August 2015, AWS announced the availability of Kinesis Data Firehose, a fully managed service for delivering real-time streaming data to destinations such as Amazon S3, Amazon Redshift, and Amazon Elasticsearch. A year later in August 2016, AWS launched Kinesis Data Analytics, enabling customers to analyze streaming data in real time using standard SQL queries. AWS introduced Kinesis Video Streams, a fully managed service for securely capturing, processing, and storing video streams for analytics and machine learning applications, was introduced by AWS in November 2017. == Components == Amazon Kinesis is composed of four main services: Kinesis Data Streams, Kinesis Data Firehose, Kinesis Data Analytics, and Kinesis Video Streams. === Kinesis Data Streams === Kinesis Data Streams is a scalable and durable real-time data streaming service that captures and processes gigabytes of data per second from multiple sources. It enables the storage and processing of data in real time, making it useful for applications that require immediate insights, such as monitoring and alerting. === Kinesis Data Firehose === Kinesis Data Firehose is a fully managed service for delivering real-time streaming data to destinations such as Amazon S3, Amazon Redshift, Amazon Elasticsearch, and AWS-partner data stores. With Data Firehose, users can configure and scale data delivery without manual intervention. === Kinesis Data Analytics === Kinesis Data Analytics enables the analysis of streaming data in real time using standard SQL or Apache Flink. === Kinesis Video Streams === Kinesis Video Streams is a fully managed service for securely capturing, processing, and storing video streams for analytics and machine learning. It supports multiple video codecs and streaming protocols, making it suitable for various use cases, such as security and surveillance, video-enabled IoT devices, and live event broadcasting. == Integration == Amazon Kinesis can be easily integrated with other AWS services, such as AWS Lambda, Amazon S3, Amazon Redshift, and Amazon OpenSearch. This integration enables developers to build end-to-end streaming data processing applications, taking advantage of the extensive AWS ecosystem. == Use cases == Some common use cases for Amazon Kinesis include: Real-time analytics: Analyzing streaming data in real time to provide immediate insights and make data-driven decisions. Log and event data collection: Collecting, processing, and analyzing log and event data generated by applications, infrastructure, and devices. IoT data processing: Processing and analyzing large volumes of data generated by IoT devices in real time. Machine learning: Ingesting and processing video streams for machine learning applications, such as object recognition, facial recognition, and sentiment analysis. == Pricing == Amazon Kinesis follows a pay-as-you-go pricing model, with costs depending on the chosen service, data volume, and processing power required. AWS provides a free tier for Kinesis Data Streams and Kinesis Data Firehose, allowing users to get started with the services at no cost.

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  • Small data

    Small data

    Small data is data that is 'small' enough for human comprehension. It is data in a volume and format that makes it accessible, informative and actionable. The term "big data" is about machines and "small data" is about people. This is to say that eyewitness observations or five pieces of related data could be small data. Small data is what we used to think of as data. The only way to comprehend Big data is to reduce the data into small, visually-appealing objects representing various aspects of large data sets (such as histogram, charts, and scatter plots). Big Data is all about finding correlations, but Small Data is all about finding the causation, the reason why. A formal definition of small data has been proposed by Allen Bonde, former vice-president of Innovation at Actuate - now part of OpenText: "Small data connects people with timely, meaningful insights (derived from big data and/or “local” sources), organized and packaged – often visually – to be accessible, understandable, and actionable for everyday tasks." Another definition of small data is: The small set of specific attributes produced by the Internet of Things. These are typically a small set of sensor data such as temperature, wind speed, vibration and status. It was estimated (2016) that “If one takes the top 100 biggest innovations of our time, perhaps around 60% to 65% percent are really based on Small Data.” as Martin Lindstrom puts it. Small data includes everything from Snapchat to simple objects such as the post-it note. Lindstrom believes we become so focused on Big-Data that we tend to forget about more basic concepts and creativity. Lindstrom defines Small Data "as seemingly insignificant observations you identify in consumers’ homes, is everything from how you place your shoes on how you hang your paintings". He thus considers that one should perfectly master the basic (Small Data) in order to mine and find correlations. == Academic Recognition and Methodology == The growing significance of "small data" as a distinct field of inquiry was highlighted by the 2024 Thematic Einstein Semester (TES) on Small Data Analysis, hosted by the Berlin Mathematics Research Center MATH+. A central focus of this semester was the transition from theoretical analysis to practical decision-making. Because small data sets are primarily used to drive specific actions, the presentation of results becomes an essential methodological step. The semester’s findings emphasized that while small data may lack volume, it often contains a high density of "many possible interpretations." Consequently, the final conference of the TES was structured around the pillars of interpretation, explanation, and knowledge gain. Participants sought to develop new mathematical and methodical representations that could accurately depict this wealth of interpretative possibilities. This work underscores that analyzing small data is not purely a computational task; it requires a robust interface between mathematics and diverse disciplines to ensure that insights are both contextually grounded and scientifically rigorous. == Uses in business == === Marketing === Bonde has written about the topic for Forbes, Direct Marketing News, CMO.com and other publications. According to Martin Lindstrom, in his book, Small Data: "{In customer research, small data is} Seemingly insignificant behavioural observations containing very specific attributes pointing towards an unmet customer need. Small data is the foundation for breakthrough ideas or completely new ways to turnaround brands." His approach is based on the combination of the observation of small samples with intuition. Marketers can obtain market insights from gathering Small Data by engaging with and observing people in their own environments. In comparison to Big Data, Small Data has the power to trigger emotions and to provide insights into the reasons behind the behaviours of customers. It may uncover detailed information on a person's extroversion or introversion, self-confidence, whether one is having problems in his/her relationship, etc. According to Lindstrom, relationships among people and customer segments are organized around four criteria: Climate: It reveals for example how a person's environment affects their diet. Rulership: The power or government in charge Religion: The prevalence of religion in a country, depending on its influence, indicates whether a person's decision making process is impacted by their belief system. Tradition: Cultural norms influence people's behaviors and interactions. Many companies underestimate the power of Small Data, using samples of millions of consumers instead of recognizing the value of closely observing small samples in their market research. In his book, Lindstrom defines "7Cs", which companies should consider in the attempt to derive meaningful customer insights and market trends through small data from their customers: Collecting: Understanding the manner in which observations are translated inside a home. Clues: Uncovering other distinctive emotional reflections that can be observed. Connecting: Identifying the consequences of emotional behaviour. Causation: Understanding what emotions are being evoked. Correlation: Identifying the initial date of appearance of the behaviour or emotion. Compensation: Identifying the unmet or unfulfilled desire. Concept: Defining the “big idea” compensation for the identified consumer need. Some of Lindstrom's clients such as Lowes Foods looked at data in a different way and actually chose to live with the customer. “As you enter their store, they have now created an amazing community where every staff member acts in a character mood, based on Small Data”. The supermarket made everything it can to make the customer feel at home. All the behaviours of employees are inspired by customer feedbacks gathered from interviews directly done at customer’s home. === Healthcare === Researchers at Cornell University started developing applications to monitor health problems in patients, based on small data. This is an initiative of Cornell's Small Data Lab, in close cooperation with Weill Cornell Medicine College, led by Deborah Estrin. The Small Data Lab developed a series of apps, focusing not only on gathering data from patients' pain but also tracking habits in areas such as grocery shopping. In the case of patients with rheumatoid arthritis for example, which has flares and remissions that do not follow a particular cycle, the app gathers information passively, thus allowing to forecast when a flare might be coming up based on small changes in behaviour. Other apps developed also include monitoring online grocery shopping, to use this information from every user to adapt their groceries to the recommendations of nutritionists, or monitoring email language to identify patterns that might indicate "fluctuations in cognitive performance, fatigue, side effects of medication or poor sleep, and other conditions and treatments that are typically self-reported and self-medicated". === Postal Service === The United States Postal Service (USPS) used optical character recognition (OCR) to automatically read and process 98% of all hand-addressed mail and 99.5% of machine-printed mail. By combining this technology with its small data sample of US zip codes, the USPS can now process more than 36,000 pieces of mail per hour. === Aerospace === In 2015, Boeing established the analytics lab for aerospace data in cooperation with the Carnegie Mellon University to leverage the university's leadership in machine learning, language technologies and data analytics. One of the initiatives projects aims to by standardize maintenance logs using AI to dramatically reduce costs. Currently, there is no standardized procedure to document maintenance logs leading to small but highly unstructured data sets. As a result, it becomes highly difficult for maintenance workers to translate these variations in maintenance logs within a short period of time. However, with AI and a narrow data set of common aircraft maintenance terminology, it becomes possible to dynamically translate these logs in real time. By using AI to enhance the speed and accuracy of the airline maintenance workflow, airlines stand to save billions according to the Harvard Business Review.

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  • AI: When a Robot Writes a Play

    AI: When a Robot Writes a Play

    AI: When a Robot Writes a Play (in Czech: AI: Když robot píše hru) is a 2021 experimental theatre play, where 90% of its script was automatically generated by artificial intelligence (the GPT-2 language model). The play is in Czech language, but an English version of the script also exists. == Creation == The play is the first result of the THEaiTRE research project, aiming to commemorate the centenary of the R.U.R. play by Karel Čapek by investigating to what extent artificial intelligence could be used to create theatre play scripts. The script of the play was created using the THEaiTRobot tool, based on the GPT-2 language model. First, the play dramaturge, David Košťák, described the initial setting of each scene in a few sentences, and wrote the first line for each character. Next, THEaiTRobot suggested a continuation of the script, which the dramaturge could use, reject, or use part of it and let the tool generate a new continuation. Another option was to manually insert another line or a scenic remark. The script was generated in English and was automatically translated to Czech by the state-of-the-art CUBBITT machine translation tool. The resulting script was then further post-edited by the dramaturge. The resulting script was made freely available for non-commercial use both in English and in Czech, with marked manually inserted texts and manual edits. The analysis shows that 90% of the English script is automatically generated, with 10% manually written or manually post-edited. In the Czech script, a larger amount of edits were made, but the analysis claims that these additional edits are corrections of errors of the automated translation and stylistic corrections which do not change the meaning of the lines as represented by the English script, but rather bring the Czech script closer to the English one. == Characters == The play contains 9 characters. The Robot appears in all the scenes, while each of the other characters appears in only one scene. Robot – The lead character, a male humanoid robot. Master – An old man, the creator of the Robot. Boy – A schoolboy. Masseuse – A sex worker in a brothel. Stranger – An engineer. Man. Psychologist. Administrator – A female clerk at an employment agency. Actress – A film actress and a model in a robot-like costume. == Plot == The play is composed of 8 scenes. It tells the story of a humanoid robot, who encounters 8 other characters and engages into various typically human situations and activities, related to death, love, sex, violence, etc. The individual scenes are not tightly linked, but there are some linking points, such as the central character of the robot or some repeated and developing themes, such as the robot's search for love. The scenes often contain some absurd turns and it is often hard to find sense in them. It is therefore a very complicated piece interpretationally, requiring the director and the actors to invest a lot of effort and creativity in finding a meaningful interpretation which would not deviate from the script. In the interpretation by Švanda theatre, who premiered the play and who also participated on the creation of the script, the scenes typically contain non-verbally expressed content which can add a lot to the meaning of the scene compared to what is contained in the actual script (as the script only contains the lines said by the characters). === Scene 1: Death === The play opens by the Robot parting with his dying Master. The Master gives the Robot several last lessons and talks with him about death, soul, and love. === Scene 2: Sense of Humour === In the second scene, the Robot meets a sad and angry Boy, who complains that he wants to go to school, that his girlfriend is crazy, that he wants to buy a car, etc. The Robot tries to help the Boy by giving him advice, but the Boy's reactions are quite negative and irritated. The Boy then repeatedly asks the Robot to tell him a joke; the Robot keeps refusing, but ultimately tells the following joke: When you are dead. When your children are dead. When your grandchildren are dead, I will be still alive. === Scene 3: Nightclub === The Robot wants to feel pleasure, so he goes to a "night club" (a brothel), where he meets a "Masseuse" (a prostitute). The Robot is initially "a bit cold", but eventually manages to enjoy the experience and falls in love with the Masseuse. In the Švanda theatre performance, the Robot and the Masseuse seem to have a sort of virtual sex without touching each other, reminiscent of the sex scene in Demolition Man. === Scene 4: Fear of the Dark === It is the night. The Robot is standing under a lamp, unable to move away from the light as he finds that he is afraid of the dark. He meets a Stranger, an engineer who tells him that robots don't have feelings and that people cannot be trusted, and keeps hurting him. In the Švanda theatre performance, the Man repeatedly zaps the Robot with some kind of electric pulse. === Scene 5: Killer Robot === A Man approaches the Robot and repeatedly asks him to kill him. Instead, the Robot sticks a finger into the Man's anus, which leads to an argument between the Man and the Robot. === Scene 6: Burn Out === The Robot meets a Psychologist, who keeps asking him lots of questions regarding his life, burnout feeling, love, relationships, and emotions. They also talk about the Robot using a device called emotion machine which helps him to get rid of stress. === Scene 7: Search for Job === The Robot comes to an employment agency. He meets an Administrator and asks her to help him find a job. He expresses the wish to become an actor, and talks about his experience as a clown. He reveals his name to be Troy McClure, which is a character from The Simpsons who is an actor. In the Švanda theatre performance, the Administrator starts to seduce the Robot once his name is revealed, which he keeps ignoring; the Administrator then becomes irritated. === Scene 8: Love at First Sight === The Robot meets a human Actress in a robotic costume and falls in love with her immediately. The Actress is first reluctant, but the Robot manages to seduce her and she also falls in love with him. The Robot tells her about a binary world, in which he lives and where he will also take her. Ultimately, the Actress agrees, and the whole play concludes by the Robot and the Actress promising each to other to always be together. In the Švanda theatre performance, the Robot does not have a physical body in this scene, we can only hear his voice and see a pulsating light (based on the line in the script where the Robot says: "I have no body. So I don't need to wear clothes. You can't see me, you only hear me."), and the Actress eventually also agrees to lose her physical body so that she can be with the Robot forever. == Theatrical performances == The play premiered on 26 February 2021 in Švanda Theatre in Prague, Czech Republic, directed by Daniel Hrbek. Due to the COVID-19 pandemic, the play was not played in front of a live audience, but it was broadcast online, in Czech language with English subtitles. The play was followed by a panel discussion by the project members and experts on artificial intelligence. The premiere was viewed by 13,498 spectators worldwide. A short trailer of the premiere is available on YouTube. In 2021, after the opening of the theatres in the Czech Republic to spectators, the play can be viewed at Švanda Theatre. The performance takes approximately 60 minutes, and is followed by a discussion of the creators with the audience. The derniere is planned for 4 February 2023. == Reception == The play received a number of reviews, both in its country of origin as well as internationally. It is praised as first of its kind, although some reviewers note the similarity to previous works, such as the musical Beyond the Fence, the play Lifestyle of the Richard and Family, or the short movie Sunspring; however, these works used less advanced technology, and either were very short (Sunspring) or necessitated a larger amount of human interventions. The reviewers note that the script is far from perfect, with many inconsistencies and nonsensical parts, and conclude that the technology is definitely not yet ready to replace human authors; however, some find some parts of the script frighteningly human-like. The amount of human intervention is a somewhat controversial topic, with some reviewers finding the human influence too large (especially in interpreting the script and putting the play on scene), while others feel that a greater amount of human intervention would have been favorable as this could greatly improve the quality of the play. The reviews also frequently comment on the amount of sex, violence and strong language in the play; this can be attributed to the method used for creating the script, where the GPT-2 language model reflects topics and language common in the human-written articles on the internet that were used to train the model. Furthermore, some r

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