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  • Hierarchical Risk Parity

    Hierarchical Risk Parity

    Hierarchical Risk Parity (HRP) is an advanced investment portfolio optimization framework developed in 2016 by Marcos López de Prado at Guggenheim Partners and Cornell University. HRP is a probabilistic graph-based alternative to the prevailing mean-variance optimization (MVO) framework developed by Harry Markowitz in 1952, and for which he received the Nobel Prize in economic sciences. HRP algorithms apply discrete mathematics and machine learning techniques to create diversified and robust investment portfolios that outperform MVO methods out-of-sample. HRP aims to address the limitations of traditional portfolio construction methods, particularly when dealing with highly correlated assets. Following its publication, HRP has been implemented in numerous open-source libraries, and received multiple extensions. == Key features == HRP portfolios have been proposed as a robust alternative to traditional quadratic optimization methods, including the Critical Line Algorithm (CLA) of Markowitz. HRP addresses three central issues commonly associated with quadratic optimizers: numerical instability, excessive concentration in a small number of assets, and poor out-of-sample performance. HRP leverages techniques from graph theory and machine learning to construct diversified portfolios using only the information embedded in the covariance matrix. Unlike quadratic programming methods, HRP does not require the covariance matrix to be invertible. Consequently, HRP remains applicable even in cases where the covariance matrix is ill-conditioned or singular—conditions under which standard optimizers fail. Monte Carlo simulations indicate that HRP achieves lower out-of-sample variance than CLA, despite the fact that minimizing variance is the explicit optimization objective of CLA. Furthermore, HRP portfolios exhibit lower realized risk compared to those generated by traditional risk parity methodologies. Empirical backtests have demonstrated that HRP would have historically outperformed conventional portfolio construction techniques. Algorithms within the HRP framework are characterized by the following features: Machine Learning Approach: HRP employs hierarchical clustering, a machine learning technique, to group similar assets based on their correlations. This allows the algorithm to identify the underlying hierarchical structure of the portfolio, and avoid that errors spread through the entire network. Risk-Based Allocation: The algorithm allocates capital based on risk, ensuring that assets only compete with similar assets for representation in the portfolio. This approach leads to better diversification across different risk sources, while avoiding the instability associated with noisy returns estimates. Covariance Matrix Handling: Unlike traditional methods like Mean-Variance Optimization, HRP does not require inverting the covariance matrix. This makes it more stable and applicable to portfolios with a large number of assets, particularly when the covariance matrix's condition number is high. == The problem: Markowitz's Curse == Portfolio construction is perhaps the most recurrent financial problem. On a daily basis, investment managers must build portfolios that incorporate their views and forecasts on risks and returns. Despite the theoretical elegance of Markowitz's mean-variance framework, its practical implementation is hindered by several limitations that undermine the reliability of solutions derived from the Critical Line Algorithm (CLA). A principal concern is the high sensitivity of optimal portfolios to small perturbations in expected returns: even minor forecasting errors can result in significantly different allocations (Michaud, 1998). Given the inherent difficulty of producing accurate return forecasts, numerous researchers have advocated for approaches that forgo expected returns entirely and instead rely solely on the covariance structure of asset returns. This has given rise to risk-based allocation methods, among which risk parity is a widely cited example (Jurczenko, 2015). While eliminating return forecasts mitigates some instability, it does not eliminate it. Quadratic programming techniques employed in portfolio optimization require the inversion of a positive-definite covariance matrix, meaning all eigenvalues must be strictly positive. When the matrix is numerically ill-conditioned—that is, when the ratio of its largest to smallest eigenvalue (its condition number) is large—matrix inversion becomes unreliable and prone to significant numerical errors (Bailey and López de Prado, 2012). The condition number of a covariance, correlation, or any symmetric (and thus diagonalizable) matrix is defined as the absolute value of the ratio between its largest and smallest eigenvalues in modulus. The figure on the right presents the sorted eigenvalues of several correlation matrices; the condition number is represented by the ratio of the first to last eigenvalues in each sequence. A diagonal correlation matrix, which is equal to its own inverse, exhibits the minimum possible condition number. As the number of correlated (or multicollinear) assets in a portfolio increases, the condition number rises. At high levels, this leads to severe numerical instability, whereby slight modifications in any matrix entry may result in drastically different inverses. This phenomenon, often referred to as Markowitz’s curse, encapsulates the paradox wherein increased correlation among assets heightens the theoretical need for diversification, yet simultaneously increases the likelihood of unstable optimization outcomes. Consequently, the potential benefits of diversification are frequently overshadowed by estimation errors. These problems are exacerbated as the dimensionality of the covariance matrix increases. The estimation of each covariance term consumes degrees of freedom, and in general, a minimum of 1 2 N ( N + 1 ) {\displaystyle {\frac {1}{2}}N(N+1)} independent and identically distributed (IID) observations is required to estimate a non-singular covariance matrix of dimension N {\displaystyle N} . For example, constructing an invertible covariance matrix of dimension 50 necessitates at least five years of daily IID observations. However, empirical evidence suggests that the correlation structure of financial assets is highly unstable over such extended periods. These difficulties are highlighted by the observation that even naïve allocation strategies—such as equally weighted portfolios—have frequently outperformed both mean-variance and risk-based optimizations in out-of-sample tests (De Miguel et al., 2009). == The solution: Hierarchical Risk Parity == The HRP algorithm addresses Markowitz's curse in three steps: Hierarchical Clustering: Assets are grouped into clusters based on their correlations, forming a hierarchical tree structure. Quasi-Diagonalization: The correlation matrix is reordered based on the clustering results, revealing a block diagonal structure. Recursive Bisection: Weights are assigned to assets through a top-down approach, splitting the portfolio into smaller sub-portfolios and allocating capital based on inverse variance. === Step 1: Hierarchical clustering === Given a T × N {\displaystyle T\times N} matrix of asset returns X {\displaystyle X} , where each column represents a time series of returns for one of N {\displaystyle N} assets over T {\displaystyle T} time periods, a hierarchical clustering process can be used to construct a tree-based representation of asset relationships. First, we compute the N × N {\displaystyle N\times N} correlation matrix ρ = ρ i , j i , j = 1 . . . N {\displaystyle \rho ={\rho _{i,j}}\;{i,j=1\;...\;N}} , where ρ i , j = c o r r ( X i , X j ) {\displaystyle \rho _{i,j}=\mathrm {corr} (X_{i},X_{j})} . From this, a pairwise distance matrix D = d i , j {\displaystyle D={d_{i,j}}} is defined using the transformation: d i , j = 1 2 ( 1 − ρ i , j ) {\displaystyle d_{i,j}={\sqrt {{\frac {1}{2}}(1-\rho _{i,j})}}} This distance function defines a proper metric space, satisfying non-negativity, identity of indiscernibles, symmetry, and the triangle inequality. Next, a secondary distance matrix D ~ = d ~ i , j {\displaystyle {\tilde {D}}={{\tilde {d}}_{i,j}}} is computed, where each entry measures the Euclidean distance between the distance profiles of two assets: d ~ i , j = ∑ n = 1 N ( d n , i − d n , j ) 2 {\displaystyle {\tilde {d}}_{i,j}={\sqrt {\sum _{n=1}^{N}(d_{n,i}-d_{n,j})^{2}}}} While d i , j {\displaystyle d_{i,j}} reflects correlation-based proximity between two assets, d ~ i , j {\displaystyle {\tilde {d}}_{i,j}} quantifies dissimilarity across the entire system, as it depends on all pairwise distances. Hierarchical clustering proceeds by identifying the pair ( i , j ) {\displaystyle (i,j)} with the smallest value of d ~ i , j {\displaystyle {\tilde {d}}_{i,j}} (for i ≠ j {\displaystyle i\neq j} ), and forming a new cluster u [ 1 ] = ( i , j ) {\displaystyle u[1]=(i,j)} .

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  • Kubity

    Kubity

    Kubity is a cloud-based 3D communication tool that works on desktop computers, the web, smartphones, tablets, augmented reality gear, and virtual reality glasses. Kubity is powered by several proprietary 3D processing engines including "Paragone" and "Etna" that prepare the 3D file for transfer over mobile devices. Kubity has practical applications for architecture, interior design, engineering, product design, film, and video games among others. The majority of its users create 3D models using SketchUp or Autodesk Revit software. Kubity products include the Kubity web app and Kubity Go (a mobile application for iOS and Android). Kubity is compatible across many platforms, devices and operating systems including: iOS, Android, Firefox, Chrome, Windows, MacOS, and Linux. == History == Kubity was created by SPK Technology (ex Kubity S.A.S.), a Paris-based software company specializing in automatic 3D data optimization and visualization. Founded in 2012 by a group of software engineers and an urban projects developer, they united around a simple idea: create a way for anyone, anywhere to simply and intuitively explore 3D models on smartphones and computers. In order to bring architects, engineers and designers together with their clients around a 3D model, it was essential to develop an interactive platform that supported multiple desktop and mobile devices for instantaneous and fluid 3D navigation. With specifications in place, 15 engineers fused together several technologies: 3D design, data compression, decimation and rendering optimization, web and mobile transfer, and virtual reality headset integration. In January 2014, the first public Kubity prototype (1.0 Amethyst) was launched to a small group of beta testers with a plug-in that allowed users to import 3D models from SketchUp to their browser. A global release was announced in April 2014 at the SketchUp Basecamp in Vail, Colorado. In May 2015, Kubity launched a web application that worked using WebGL technology (2.0 Citrine). For the first time, users were able to drag and drop any SketchUp file in a web browser without having to install a plug-in. In December 2015, Kubity launched a mobile application on the App Store for iPhone, iPod, and iPad as well as on Google Play for Android devices (3.0 Druzy). In November 2016, Kubity launched support for Oculus Rift and HTC Vive (4.0 Emerald). Beginning in November 2017, Kubity launched a full suite rollout of mobile applications over six months that included Kubity AR for augmented reality, Kubity VR for virtual reality, and Kubity Mirror for remote presentations and screen mirroring (5.0 Feldspar). In September 2018, a one-click plugin for SketchUp and Revit (Kubity PRO), along with a mobile-first revamp of Kubity Go was launched, allowing PRO-to-Go device pairing for automatic mobile sync (6.0 Gypsum). In early 2019, the Kubity Go application was updated to include fully integrated AR, VR, and screen mirroring functionalities, killing off the dedicated companion apps Kubity AR, Kubity VR and Kubity Mirror in the process (7.0 Heliotrope). In January 2020, support for the Kubity PRO plugin for SketchUp and Revit was migrated to a SketchUp-only web app. == Technology == Kubity is powered by a proprietary 3D crystallization engine known as "Paragone"; a technology developed by SPK Technology. Paragone takes constrained information from a 3D file and runs it through the "BlockWave" algorithm (US Patent 10,482.629), also developed by SPK Technology. BlockWave is a multiphase optimization algorithm that combines 3D design, data compression, decimation and rendering optimization, web and mobile transfer, and mixed reality headset integration to create a crystallized universal format of the original file. One phase of the BlockWave algorithm is based on the quadric-based polygonal surface simplification algorithm, performed using predefined heuristics, and is associated with a plurality of simplified versions of the 3D model, each version being associated with a predefined level of detail adapted to the user specific end device. BlockWave extracts data content, geometry and textures, then sets quadrics for each top of the original 3D model, and identifies pairs of adjacent tops linked by vertices. The algorithm uses a local collapsing operator and a top-plan error metric to obtain a fixed number of faces or a maximum defined error; 3D meshing is simplified by replacing two points with one, then deleting the degrading faces and updating adjacent relations. Once decimation is completed, texture optimization is set using texture target parameters allowing maximized GPU memory to improve computing time. With texture encoding completed, the crystallized universal 3D file can now be easily opened on any user-specific end device and played across most digital devices with real-time rendering. == Features == === 3D Crystallization === A user converts (or crystallizes) a 3D file by exporting it with the Kubity web app. Crystallization adds features like AR/VR and cinematic fly-through tour as well as assigns the model a dedicated QR code. === Automatic Mobile Sync === When a 3D model is exported, it is automatically synced to Kubity Go on the user's mobile device. From there, it can be accessed, explored, and shared with others with or without an internet connection. === Security and Management === User models can be managed all in one place on Kubity Go or in a browser from their account. Models can be renamed, password-protected, shared, and played. === Augmented Reality === Developed using Apple ARKit and Google ARCore technology, Kubity Go's augmented reality feature maps the environment in a room detecting horizontal planes like tables and floors to track and place 3D objects. By blending digital objects and information with the environment, Kubity allows users to interact with 3D models in true augmented reality. Built-in communication features allows users to instantly share 3D models with anyone over text, email, social media, or direct device-to-device with a QR Code. Platform Support AR supports devices running iOS11 including: iPhone SE, iPhone 6s, iPhone 6s Plus, iPhone 7, iPhone 7 Plus, iPhone 8, iPhone X, all iPad Pro models, and iPad (2017). AR for Android requires Android 7.0 or later and access to the Google Play Store. === Virtual Reality === VR allows users to explore SketchUp models and Revit projects on-the-go right from a mobile device using Oculus Go, Google Cardboard, Samsung Gear VR, or the glasses-free Magic Window feature. Kubity's virtual reality feature is compatible with Oculus Go, Google Cardboard viewers and other cardboard compatible devices including clip-on style VR glasses like Homido Mini, as well as the mobile virtual reality headset, Samsung Gear VR. Samsung Gear VR supports: Galaxy S6, Galaxy S6 Edge, Galaxy S6 Edge+, Samsung Galaxy Note 5, Galaxy S7, Galaxy S7 Edge, Galaxy S8, Galaxy S8+, Samsung Galaxy Note Fan Edition, Samsung Galaxy Note 8, Samsung Galaxy A8/A8+ (2018), and Samsung Galaxy S9/Galaxy S9+. === Screen Mirroring === Screen mirroring allows a user to sync the sender device to a receiver on a webpage, then control from the sender device to give a remote presentation of the 3D model. Devices are easily synced by entering a six-digit number displayed on the receiving computer. == Platform support == On iOS, the Kubity application is compatible with devices running on the version 9.0 or higher. On Android, Kubity is compatible with devices running on the version 4.4 “Kit Kat” or higher. The web version of Kubity applications currently support web browsers compatible with WebGL2 : Mozilla Firefox and Google Chrome. AR is compatible with devices running iOS11 including: iPhone SE, iPhone 6s, iPhone 6s Plus, iPhone 7, iPhone 7 Plus, iPhone 8, iPhone X, all iPad Pro models, and iPad (2017), and Android devices. Requires Android 7.0 or later and access to the Google Play Store. VR is compatible with Google Cardboard viewers and other cardboard compatible devices including clip-on style VR glasses like Homido Mini, as well as the Samsung Gear VR and Oculus Go. Samsung Gear VR supports: Galaxy S6, Galaxy S6 Edge, Galaxy S6 Edge+, Samsung Galaxy Note 5, Galaxy S7, Galaxy S7 Edge, Galaxy S8, Galaxy S8+, Samsung Galaxy Note Fan Edition, Samsung Galaxy Note 8, Samsung Galaxy A8/A8+ (2018) and Samsung Galaxy S9/Galaxy S9+.

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  • European Cloud Partnership

    European Cloud Partnership

    The European Cloud Partnership (ECP) is an advisory group set up by the European Commission as part of the European Cloud Computing Strategy to provide guidance on the development of cloud computing in the European Union. The ECP is led by a steering board composed of representatives of the IT and telecom industry as well as European government policymakers. == History == After publishing a document, "Unleashing the Potential of Cloud Computing in Europe", the European Commission set up the European Cloud Partnership in 2012, with a steering board including both government and industry representatives. The ECP's first meeting was held on 19 November 2012; it was chaired by the President of Estonia Toomas Hendrik Ilves. In 2013 the ECP began drafting its charter. That year, as information about the PRISM scandal came to light, the ECP emphasized the need for Europe to develop its own cloud infrastructure, rather than depend on that of the United States. It completed a report titled "Trusted Cloud Europe" in February 2014 defining its policy, and outlining a process for effective public and private sector participation in cloud computing development in Europe. The report recommended that the commission identify technical, legal and operational best practices, and promote these through certifications and guidelines, and facilitate recognition across national boundaries. The report also recommended that the commission identify cloud computing stakeholders and help them work together through consultations and workshops. In March 2014, the European Commission invited external parties to submit opinions, take part in a discussion forum and complete an online survey in response to the report.

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  • Cryptee

    Cryptee

    Cryptee is a privacy focused client-side encrypted and cross-platform productivity suite and data storage service. == History == Cryptee was founded in 2017, by John Ozbay, a cybersecurity researcher, commenter, and activist, to exclusively focus on providing a secure document editing service similar to Google Docs and Photos for everyone, with a particular focus on victims and survivors of domestic abuse, journalists and reporters. == Software == Users can write personal documents, notes, journals, store images, videos, and various kinds of other files. The source code of Cryptee is open source and publicly available to allow anyone to audit the service with ease, and help identify errors or potential vulnerabilities in a public and transparent manner. Cryptee has a few key features that differentiate it from other services in the industry, such as its Ghost Folders and Ghost Albums features, built specifically with victims and survivors of domestic abuse, journalists and reporters in mind. Cryptee allows users to hide (ghost) folders for plausible deniability also as known as deniable encryption in the field of cryptography and steganography, and ensure privacy even under coercion. === Features === Cryptee Docs' features include: To-do lists, Markdown support, KaTeX math and file attachments. cross-platform accessible, as it is a progressive web app. Bulk transfer from other note taking apps such as Evernote. Encrypted PDF and print-accurate (A4 and U.S. Letter paper-sized) text editing. Ability to edit docx files Cryptee Photos' features include: Ability to create slideshows. Ability to store original quality of photos. Ability to tag photos for organization. === Commercial strategy === The company's commercial strategy is focused on offering to its users an open source and transparent Photo Storage, Document Editor and Cloud Storage services without trackers or advertisements as it seeks to compete with Google Docs, Google Photos and similar services through its offerings. === Privacy === Cryptee utilizes zero-access storage to safe-keep all users' sensitive digital belongings. == Advocacy == === Lockdown mode === In July 2022, to fortify iPhones against the Pegasus Spyware, Apple announced a new, upcoming Lockdown Mode feature in iOS 16, welcomed by many experts. In the following weeks after Apple's announcement, in August 2022, the Founder and CEO of Cryptee, and privacy activist John Ozbay published their research detailing shortcoming of Apple's Lockdown Mode. They demonstrated that enabling Lockdown Mode makes it possible for all websites and online ads to be able to detect if users have Lockdown Mode enabled or not. This was due to the fact that disabling web fonts (an attack surface) was detectable by websites. === Confrontations against Apple === ==== On PWAs ==== In February 2024, Apple announced plans to kill progressive web apps on iOS devices in the EU, claiming it was to comply with the Digital Markets Act (DMA). The announcement was criticized as anti-competitive by many in the tech industry, including by Tim Sweeney, the CEO of Epic Games. In response, Cryptee started working together with Open Web Advocacy (OWA), an international not-for-profit digital rights group to advocate for the future of the open web, promote web browser choice on mobile operating systems through challenging Apple's anti-competitive third party browser engine ban, and to champion the use and equality of progressive web apps over native apps, by reaching out to the European Union's Digital Markets Act (DMA) team. To better understand the consequences of Apple's decision to kill web apps, the EU announced that they "seek to investigate Apple over cutting off web apps", and that they sent "requests for information to Apple and to app developers, who can provide useful information for our assessment". Apart from sending a response to the EU, Cryptee, along with the OWA, launched an open letter to Tim Cook, which in 48 hours, got thousands of signatories including European Parliament Members Karen Melchior and Patrick Breyer; and thousands of other developers and organizations from over 100 countries. Consequently, 24 hours later, Apple backed off, and reversed course on its plan to cut off progressive web apps in the EU. ==== Ozbay's representations ==== Following the events, eventually on March 18, 2024, Founder and CEO of Cryptee John Ozbay represented the Open Web Advocacy group in European Union's Digital Markets Act (DMA) hearing for Apple. At the hearing, OWA confronted Apple, accused Apple of "maliciously intending to undermine user choice", and stated that there was no defense for Apple's behavior. In response, according to the tech news outlet Ars Technica, Apple's spokesperson "seemed to dodge Ozbay's question". ==== Cooperation with the EU ==== Within a week of the hearing, the European Union announced a DMA non-compliance investigation against Apple and United States' Department of Justice filed an antitrust lawsuit against Apple. A few months later, on June 27, 2024, Cryptee, in cooperation with EDRi — an international advocacy group, along with Article 19 — a British international human rights organization, Privacy International, F-Droid, Free Software Foundation Europe, Guardian Project and others have submitted a comprehensive analysis to the European Commission about how Apple's plans to comply with the Digital Markets Act are insufficient. == Reviews == In a 2018 article, Wall Street Journal's MarketWatch reviewed Cryptee, articulating the fact that Cryptee offers zero-access storage for photos, files, documents and notes, and pointed out that: "Being based in Estonia puts Cryptee outside the “14 eyes jurisdiction,” an international surveillance alliance of European Union and North American countries, making it less likely it will be targeted with demands for data". In addition, the review highlighted Cryptee's Ghost Folders feature which ensures privacy even under coercion. In a 2019 article, Reclaim The Net named Cryptee as one of the "5 great privacy-focused Evernote alternatives to keep your notes safe", underlining that: "When it comes to security, this app is state of the art." and that "When making this app, the developers thought about every aspect of security and have taken every precaution to make it as secure as possible.". The review further underscored Cryptee's open-source nature, its strong encryption, and easy migration features. In a 2021 article, The Verge reviewed Cryptee, pointing out that Cryptee, based out of Europe, is one of the main photo storage service alternatives to Google Photos, and that it's their recommendation for users who are "concerned about privacy and like the idea of encryption" as Cryptee "offers to keep all your photos encrypted using AES-256". In a 2024 article, Beebom, enlisted Cryptee as one of the "7 best iCloud Photos Alternatives for iPhone and iPad", complimenting Cryptee's simplicity, its use of encryption to safeguard users' photos against hacking by not storing any unencrypted data. The article also provided further attention to Cryptee's additional features such as such as Ghost Albums, slideshows, easy-to-use drag and drop uploads, tagging and users' ability to store original-quality photos on Cryptee, concluding that Cryptee is "a safe bet if you are on the lookout for a privacy-centric iCloud Photos alternative".

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  • RCUDA

    RCUDA

    rCUDA, which stands for Remote CUDA, is a type of middleware software framework for remote GPU virtualization. Fully compatible with the CUDA application programming interface (API), it allows the allocation of one or more CUDA-enabled GPUs to a single application. Each GPU can be part of a cluster or running inside of a virtual machine. The approach is aimed at improving performance in GPU clusters that are lacking full utilization. GPU virtualization reduces the number of GPUs needed in a cluster, and in turn, leads to a lower cost configuration – less energy, acquisition, and maintenance. The recommended distributed acceleration architecture is a high performance computing cluster with GPUs attached to only a few of the cluster nodes. When a node without a local GPU executes an application needing GPU resources, remote execution of the kernel is supported by data and code transfers between local system memory and remote GPU memory. rCUDA is designed to accommodate this client-server architecture. On one end, clients employ a library of wrappers to the high-level CUDA Runtime API, and on the other end, there is a network listening service that receives requests on a TCP port. Several nodes running different GPU-accelerated applications can concurrently make use of the whole set of accelerators installed in the cluster. The client forwards the request to one of the servers, which accesses the GPU installed in that computer and executes the request in it. Time-multiplexing the GPU, or in other words sharing it, is accomplished by spawning different server processes for each remote GPU execution request. == rCUDA v20.07 == The rCUDA middleware enables the concurrent usage of CUDA-compatible devices remotely. rCUDA employs either the InfiniBand network or the socket API for the communication between clients and servers. rCUDA can be useful in three different environments: Clusters. To reduce the number of GPUs installed in High Performance Clusters. This leads to energy savings, as well as other related savings like acquisition costs, maintenance, space, cooling, etc. Academia. In commodity networks, to offer access to a few high performance GPUs concurrently to many students. Virtual Machines. To enable the access to the CUDA facilities on the physical machine. The current version of rCUDA (v20.07) supports CUDA version 9.0, excluding graphics interoperability. rCUDA v20.07 targets the Linux OS (for 64-bit architectures) on both client and server sides. CUDA applications do not need any change in their source code in order to be executed with rCUDA.

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  • Dave's Redistricting

    Dave's Redistricting

    Dave's Redistricting App (DRA) is an online web app originally created by Dave Bradlee that allows anyone to simulate redistricting a U.S. state's congressional and legislative districts. == Purpose == According to Bradlee, the software was designed to "put power in people's hands," and so that they "can see how the process works, so it's a little less mysterious than it was 10 years ago." Bradlee has noticed that many citizens are taking this process seriously and using his app to create legitimate redistricting maps that could be put in place. Some websites have called Bradlee the pioneer and cause of the rise of do-it-yourself redistricting. States such as Montana in 2021 allowed the general population to use it to submit redistricting proposals following the 2020 United States Census. Dave's Redistricting has frequently been mentioned as a resource that can be used to combat gerrymandering, given that the public has free access to it. Political science firms such as FiveThirtyEight have used the website to draw examples of gerrymandered districts, including on their famous Atlas of Redistricting. Dave Bradlee built the first generation of DRA. DRA 2020 is built by a small team of volunteers—Dave Bradlee, Terry Crowley, Alec Ramsay, and David Rinn—all with a shared passion for technology & democracy and all Microsoft veterans. Their mission is to empower civic organizations and citizen activists to advocate for fair congressional and legislative districts and increased transparency in the redistricting process. == Functions == Users can redraw the congressional and state legislative districts for all 50 states, the District of Columbia, and Puerto Rico using a variety of census and election datasets including Cook PVI. Maps can be optimized for different criteria. DRA 2020 added several major features to the first generation app: Sharing & collaborative editing of maps, like Google Docs Multiple statewide elections for all 50 states including the ability to import your own data Comprehensive analytics for evaluating and comparing maps Custom overlays, and Block-level editing DRA remains free to use. == Versions == 2.2: This uses Bing Maps, an outdated software that projects the districts of a single state onto a map of the United States. 2.5: After Bing Maps announced that it would no longer be updating for the foreseen future, the U.S. Map feature was removed. DRA 2020: At the end of 2018, a beta version of 2020 was released. This version that did not require Microsoft Silverlight and could be used in any web browser. DRA 2020 has been under continuous development since and is built using React (JavaScript library), Mapbox, OpenStreetMap, TypeScript, Node.js, Amazon Web Services, as well as many open source components, tools, and icons.

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  • Color quantization

    Color quantization

    In computer graphics, color quantization or color image quantization is quantization applied to color spaces; it is a process that reduces the number of distinct colors used in an image, usually with the intention that the new image should be as visually similar as possible to the original image. Computer algorithms to perform color quantization on bitmaps have been studied since the 1970s. Color quantization is critical for displaying images with many colors on devices that can only display a limited number of colors, usually due to memory limitations, and enables efficient compression of certain types of images. The name "color quantization" is primarily used in computer graphics research literature; in applications, terms such as optimized palette generation, optimal palette generation, or decreasing color depth are used. Some of these are misleading, as the palettes generated by standard algorithms are not necessarily the best possible. == Algorithms == Most standard techniques treat color quantization as a problem of clustering points in three-dimensional space, where the points represent colors found in the original image and the three axes represent the three color channels. Almost any three-dimensional clustering algorithm can be applied to color quantization, and vice versa. After the clusters are located, typically the points in each cluster are averaged to obtain the representative color that all colors in that cluster are mapped to. The three color channels are usually red, green, and blue, but another popular choice is the Lab color space, in which Euclidean distance is more consistent with perceptual difference. The most popular algorithm by far for color quantization, invented by Paul Heckbert in 1979, is the median cut algorithm. Many variations on this scheme are in use. Before this time, most color quantization was done using the population algorithm or population method, which essentially constructs a histogram of equal-sized ranges and assigns colors to the ranges containing the most points. A more modern popular method is clustering using octrees, first conceived by Gervautz and Purgathofer and improved by Xerox PARC researcher Dan Bloomberg. If the palette is fixed, as is often the case in real-time color quantization systems such as those used in operating systems, color quantization is usually done using the "straight-line distance" or "nearest color" algorithm, which simply takes each color in the original image and finds the closest palette entry, where distance is determined by the distance between the two corresponding points in three-dimensional space. In other words, if the colors are ( r 1 , g 1 , b 1 ) {\displaystyle (r_{1},g_{1},b_{1})} and ( r 2 , g 2 , b 2 ) {\displaystyle (r_{2},g_{2},b_{2})} , we want to minimize the Euclidean distance: ( r 1 − r 2 ) 2 + ( g 1 − g 2 ) 2 + ( b 1 − b 2 ) 2 . {\displaystyle {\sqrt {(r_{1}-r_{2})^{2}+(g_{1}-g_{2})^{2}+(b_{1}-b_{2})^{2}}}.} This effectively decomposes the color cube into a Voronoi diagram, where the palette entries are the points and a cell contains all colors mapping to a single palette entry. There are efficient algorithms from computational geometry for computing Voronoi diagrams and determining which region a given point falls in; in practice, indexed palettes are so small that these are usually overkill. Color quantization is frequently combined with dithering, which can eliminate unpleasant artifacts such as banding that appear when quantizing smooth gradients and give the appearance of a larger number of colors. Some modern schemes for color quantization attempt to combine palette selection with dithering in one stage, rather than perform them independently. A number of other much less frequently used methods have been invented that use entirely different approaches. The Local K-means algorithm, conceived by Oleg Verevka in 1995, is designed for use in windowing systems where a core set of "reserved colors" is fixed for use by the system and many images with different color schemes might be displayed simultaneously. It is a post-clustering scheme that makes an initial guess at the palette and then iteratively refines it. In the early days of color quantization, the k-means clustering algorithm was deemed unsuitable because of its high computational requirements and sensitivity to initialization. In 2011, M. Emre Celebi reinvestigated the performance of k-means as a color quantizer. He demonstrated that an efficient implementation of k-means outperforms a large number of color quantization methods. The high-quality but slow NeuQuant algorithm reduces images to 256 colors by training a Kohonen neural network "which self-organises through learning to match the distribution of colours in an input image. Taking the position in RGB-space of each neuron gives a high-quality colour map in which adjacent colours are similar." It is particularly advantageous for images with gradients. Finally, one of the newer methods is spatial color quantization, conceived by Puzicha, Held, Ketterer, Buhmann, and Fellner of the University of Bonn, which combines dithering with palette generation and a simplified model of human perception to produce visually impressive results even for very small numbers of colors. It does not treat palette selection strictly as a clustering problem, in that the colors of nearby pixels in the original image also affect the color of a pixel. See sample images. == History and applications == In the early days of PCs, it was common for video adapters to support only 2, 4, 16, or (eventually) 256 colors due to video memory limitations; they preferred to dedicate the video memory to having more pixels (higher resolution) rather than more colors. Color quantization helped to justify this tradeoff by making it possible to display many high color images in 16- and 256-color modes with limited visual degradation. Many operating systems automatically perform quantization and dithering when viewing high color images in a 256 color video mode, which was important when video devices limited to 256 color modes were dominant. Modern computers can now display millions of colors at once, far more than can be distinguished by the human eye, limiting this application primarily to mobile devices and legacy hardware. Nowadays, color quantization is mainly used in GIF and PNG images. GIF, for a long time the most popular lossless and animated bitmap format on the World Wide Web, only supports up to 256 colors, necessitating quantization for many images. Some early web browsers constrained images to use a specific palette known as the web colors, leading to severe degradation in quality compared to optimized palettes. PNG images support 24-bit color, but can often be made much smaller in filesize without much visual degradation by application of color quantization, since PNG files use fewer bits per pixel for palettized images. The infinite number of colors available through the lens of a camera is impossible to display on a computer screen; thus converting any photograph to a digital representation necessarily involves some quantization. Practically speaking, 24-bit color is sufficiently rich to represent almost all colors perceivable by humans with sufficiently small error as to be visually identical (if presented faithfully), within the available color space. However, the digitization of color, either in a camera detector or on a screen, necessarily limits the available color space. Consequently there are many colors that may be impossible to reproduce, regardless of how many bits are used to represent the color. For example, it is impossible in typical RGB color spaces (common on computer monitors) to reproduce the full range of green colors that the human eye is capable of perceiving. With the few colors available on early computers, different quantization algorithms produced very different-looking output images. As a result, a lot of time was spent on writing sophisticated algorithms to be more lifelike. === Quantization for image compression === Many image file formats support indexed color. A whole-image palette typically selects 256 "representative" colors for the entire image, where each pixel references any one of the colors in the palette, as in the GIF and PNG file formats. A block palette typically selects 2 or 4 colors for each block of 4x4 pixels, used in BTC, CCC, S2TC, and S3TC. === Editor support === Many bitmap graphics editors contain built-in support for color quantization, and will automatically perform it when converting an image with many colors to an image format with fewer colors. Most of these implementations allow the user to set exactly the number of desired colors. Examples of such support include: Photoshop's Mode→Indexed Color function supplies a number of quantization algorithms ranging from the fixed Windows system and Web palettes to the proprietary Local and Global algorithms for generating palettes suited to a particu

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  • PerfKitBenchmarker

    PerfKitBenchmarker

    PerfKit Benchmarker is an open source benchmarking tool used to measure and compare cloud offerings. PerfKit Benchmarker is licensed under the Apache 2 license terms. PerfKit Benchmarker is a community effort involving over 500 participants including researchers, academic institutions and companies together with the originator, Google. == General == PerfKit Benchmarker (PKB) is a community effort to deliver a repeatable, consistent, and open way of measuring Cloud Performance. It supports a growing list of cloud providers including: Alibaba Cloud, Amazon Web Services, CloudStack, DigitalOcean, Google Cloud Platform, Kubernetes, Microsoft Azure, OpenStack, Rackspace, IBM Bluemix (Softlayer). In addition to Cloud Providers to supports container orchestration including Kubernetes [1] and Mesos [2] and local "static" workstations and clusters of computers [3]. The goal is to create an open source living benchmark [framework] that represents how Cloud developers are building applications, evaluating Cloud alternatives, learning how to architect applications for each cloud. Living because it will change and morph quickly as developers change. PerfKit Benchmarker measures the end to end time to provision resources in the cloud, in addition to reporting on the most standard metrics of peak performance, e.g.: latency, throughput, time-to-complete, IOPS. PerfKit Benchmarker reduces the complexity in running benchmarks on supported cloud providers by unified and simple commands. It's designed to operate via vendor provided command line tools. PerfKit Benchmarker contains a canonical set of public benchmarks. All benchmarks are running with default/initial state and configuration (Not tuned to in favor of any providers). This provides a way to benchmark across cloud platforms, while getting a transparent view of application throughput, latency, variance, and overhead. == History == PerfKit Benchmarker (PKB) was started by Anthony F. Voellm, Alain Hamel, and Eric Hankland at Google in 2014. Once an initial "alpha" was in place Anthony F. Voellm and Ivan Santa Maria Filho built a community including ARM, Broadcom, Canonical, CenturyLink, Cisco, CloudHarmony, CloudSpectator, EcoCloud@EPFL, Intel, Mellanox, Microsoft, Qualcomm Technologies, Inc., Rackspace, Red Hat, Tradeworx Inc., and Thesys Technologies LLC. This community worked together behind the scenes in a private GitHub project to create an open way to measure cloud performance. This community released the first public "beta" was released on February 11, 2015, and announced in a blog post at which point the GitHub project was open to everyone. After almost a year and with large adaption (600+ participants on GitHub) the V1.0.0 was released along with a detailed architectural design on December 10, 2015. == Benchmarks == A list of available benchmarks from PerfKitBenchmarker: (The latest set of benchmarks can be found at GitHub readme file.) == Industry participants == Since Google open sourced the PerfKitBenchmarker, it became a community effort from over 30 leading researchers, academic schools and industry companies. Those organizations include: ARM, Broadcom, Canonical, CenturyLink, Cisco, CloudHarmony, Cloud Spectator, EcoCloud@EPFL, Intel, Mellanox, Microsoft, Qualcomm Technologies, Rackspace, Red Hat, and Thesys Technologies. In addition, Stanford and MIT are leading quarterly discussions on default benchmarks and settings proposed by the community. EcoCloud@EPFL is integrating CloudSuite into PerfKit Benchmarker. == Example runs == On Google Cloud Platform On AWS On Azure On Rackspace On a local machine

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  • Drop shadow

    Drop shadow

    In graphic design and computer graphics, a drop shadow is a visual effect consisting of a drawing element which looks like the shadow of an object, giving the impression that the object is raised above the objects behind it. The drop shadow is often used for elements of a graphical user interface such as windows or menus, and for simple text. The text label for icons on desktops in many desktop environments has a drop shadow, as this effect effectively distinguishes the text from any colored background it may be in front of. A simple way of drawing a drop shadow of a rectangular object is to draw a gray or black area underneath and offset from the object. In general, a drop shadow is a copy in black or gray of the object, drawn in a slightly different position. Realism may be increased by: Darkening the colors of the pixels where the shadow casts instead of making them gray. This can be done with alpha blending the shadow with the area it is cast on. Softening the edges of the shadow. This can be done by adding Gaussian blur to the shadow's alpha channel before blending. Inset drop shadows are a type which draws the shadows inside the element. This allows the interface element to appear as if it is sunken into the interface. == Photo editing == In photo editing or photography post-production, a drop shadow may be added right beneath a model or product in the image. It is used to create contrast between the background and the subject. To add a drop shadow, retouchers use graphic editing tools like Adobe Photoshop. Drop shadows are often used as a visual effect in e-commerce. This is done to improve the presentation of product images and create depth in the image. == Use == Generally, window managers which are capable of compositing allow drop shadow effects, whereas incapable window managers do not. In some operating systems like macOS, drop shadow is used to differentiate between active and inactive windows. Websites are able to use drop shadow effects through the CSS properties box-shadow, text-shadow, and drop-shadow() filter function in filter. The first two are used for elements and text respectively, while the filter applies to the element's content, letting it support oddly shaped elements or transparent images.

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  • Write or Die

    Write or Die

    Write or Die is an online web application designed to combat writer's block by letting users of the application punish themselves if they slow down or stop typing in the application's window. How severe the punishments are depends on the mode the user chooses, which ranges from "Gentle" to "Kamikaze". It was reviewed by publications PCWorld, the Los Angeles Times and The Guardian, and it was most notably used by writers Helen Oyeyemi and David Nicholls. The creator, Jeff Printy, explained that he wrote the application because he wants "to be published and make a living as a writer."

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  • StatCrunch

    StatCrunch

    StatCrunch is a web-based statistical software application from Pearson Education. StatCrunch was originally created for use in college statistics courses. As a full-featured statistics package, it is now also used for research and for other statistical analysis purposes. == History == American statistics professor Webster West created StatCrunch in 1997. Over the next 19 years West assisted by others added many more statistical procedures and graphing capabilities, and made user interface improvements. In 2005, West received two awards for StatCrunch: the CAUSEweb Resource of the Year Award and the MERLOT Classics Award. In 2013, the StatCrunch Java code was rewritten in JavaScript in order to avoid Java browser security problems, and so that it would run on iOS and Android. In 2015, new ways of importing data were added, including importing multi-page data directly from Wikipedia tables and other Web sources, and also importing with drag-and-drop for various data formats. In 2016, StatCrunch was acquired by Pearson Education, which had already been serving as the primary distributor of StatCrunch for several years. == Software == A StatCrunch license is included with many of Pearson's statistical textbooks. Because StatCrunch is a web application, it works on multiple platforms, including Windows, macOS, iOS, and Android. Data in StatCrunch is represented in a "data table" view, which is similar to a spreadsheet view, but unlike spreadsheets, the cells in a data table can only contain numbers or text. Formulas cannot be stored in these cells. There are many ways to import data into StatCrunch. Data can be typed directly into cells in the data table. Entire blocks of data may be cut-and-pasted into the data table. Text files (.csv, .txt, etc.) and Microsoft Excel files (.xls and .xlsx) can be drag-and-dropped into the data table. Data can be pulled into StatCrunch directly from Wikipedia tables or other Web tables, including multi-page tables. Data can be loaded directly from Google Drive and Dropbox. Shared data sets saved by other StatCrunch community users can be searched for by title or keyword and opened in a data table. Graphs, results, and reports created by StatCrunch can be shared with other users, in addition to the sharing of data sets. StatCrunch has a library of data transformation functions. StatCrunch can also recode and reorganize data. All data is stored in memory, and all processing happens on the client, so response is fast, even with large data sets. StatCrunch can interact with multiple graphs simultaneously. If a user selects a data point on one graph, then that same data point is highlighted on all other displayed graphs. In addition to standard statistical and graphing procedures, StatCrunch has a collection of about forty "applets" which illustrate statistical concepts interactively.

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  • List of Go software and tools

    List of Go software and tools

    This is a list of Go software and tools, including compilers, development environments, build tools, testing frameworks, web frameworks, database tools, and related software for the Go programming language. == Core toolchain == Go — programming language and toolchain go command — build and package tool gofmt — source code formatter go vet — static analysis tool == Compilers and runtimes == gc — default Go compiler gccgo — GCC front end for Go GopherJS — Go-to-JavaScript compiler gollvm — Go compiler using the LLVM backend llgo — experimental Go frontend for LLVM TinyGo — compiler for embedded systems and WebAssembly Yaegi — Go interpreter == Development environments and editors == Emacs — text editor with Go support GoLand — JetBrains integrated development environment LiteIDE — Go-focused integrated development environment Neovim — text editor with Go support TextMate — text editor with Go support Vim — text editor with Go support Visual Studio Code — editor with Go support == Language servers and editor tools == delve — debugger gopls — Go language server golangci-lint — lint runner revive — linter staticcheck — static analysis tool == Build, dependency and release tools == Air — live reload development tool dep — deprecated dependency manager Go modules — dependency management system Goreleaser — release automation tool Mage — build tool Task — task runner == Testing and benchmarking == benchstat — benchmark comparison tool Ginkgo — testing framework GoMock — mock generation tool testify — testing toolkit testing — standard testing package == Web frameworks and HTTP tools == Beego — web framework Caddy — web server Chi — router Echo — web framework Fiber — web framework Gin — web framework Gorilla Mux — router Hugo — static site generator Revel — web framework Traefik — reverse proxy and load balancer == RPC and API tools == Goa — API design framework gRPC — remote procedure call framework grpc-gateway — REST gateway oapi-codegen — OpenAPI code generator Swag — OpenAPI documentation tool == Database and ORM tools == Bun — SQL toolkit and ORM CockroachDB client libraries — database drivers and tools ent — entity framework GORM — object–relational mapper sqlx — SQL toolkit == Command-line and terminal tools == Bubble Tea — terminal user interface framework Cobra — command-line framework pflag — flag parsing library urfave/cli — command-line framework Viper — configuration library == GUI toolkits and application frameworks == Fyne — cross-platform graphical user interface toolkit == Documentation, generation and analysis == errcheck — unchecked error checker godoc — documentation tool goimports — import management tool mockgen — mock generator pkgsite — package documentation site Prometheus — monitoring and alerting toolkit stringer — code generation tool wire — dependency injection code generator == Package hosting and community services == GoCenter — former Go package repository pkg.go.dev — package documentation and discovery site proxy.golang.org — module proxy == Major applications written in Go == Consul — service networking platform Docker — containerization platform InfluxDB — time-series database written in Go Kubernetes — container orchestration platform Ollama — platform for running and managing large language models locally Terraform — infrastructure as code tool Vault — secrets management tool

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  • Single particle analysis

    Single particle analysis

    Single particle analysis is a group of related computerized image processing techniques used to analyze images from transmission electron microscopy (TEM). These methods were developed to improve and extend the information obtainable from TEM images of particulate samples, typically proteins or other large biological entities such as viruses. Individual images of stained or unstained particles are very noisy, making interpretation difficult. Combining several digitized images of similar particles together gives an image with stronger and more easily interpretable features. An extension of this technique uses single particle methods to build up a three-dimensional reconstruction of the particle. Using cryo-electron microscopy it has become possible to generate reconstructions with sub-nanometer, near-atomic resolution resolution first in the case of highly symmetric viruses, and now in smaller, asymmetric proteins as well. == Techniques == Single particle analysis can be done on both negatively stained and vitreous ice-embedded transmission electron cryomicroscopy (CryoTEM) samples. Single particle analysis methods are, in general, reliant on the sample being homogeneous, although techniques for dealing with conformational heterogeneity are being developed. Images (micrographs) are taken with an electron microscope using charged-coupled device (CCD) detectors coupled to a phosphorescent layer (in the past, they were instead collected on film and digitized using high-quality scanners). The image processing is carried out using specialized software programs, often run on multi-processor computer clusters. Depending on the sample or the desired results, various steps of two- or three-dimensional processing can be done. === Alignment and classification === Biological samples, and especially samples embedded in thin vitreous ice, are highly radiation sensitive, thus only low electron doses can be used to image the sample. This low dose, as well as variations in the metal stain used (if used) means images have high noise relative to the signal given by the particle being observed. By aligning several similar images to each other so they are in register and then averaging them, an image with higher signal-to-noise ratio can be obtained. As the noise is mostly randomly distributed and the underlying image features constant, by averaging the intensity of each pixel over several images only the constant features are reinforced. Typically, the optimal alignment (a translation and an in-plane rotation) to map one image onto another is calculated by cross-correlation. However, a micrograph often contains particles in multiple different orientations and/or conformations, and so to get more representative image averages, a method is required to group similar particle images together into multiple sets. This is normally carried out using one of several data analysis and image classification algorithms, such as multi-variate statistical analysis and hierarchical ascendant classification, or k-means clustering. Often data sets of tens of thousands of particle images are used, and to reach an optimal solution an iterative procedure of alignment and classification is used, whereby strong image averages produced by classification are used as reference images for a subsequent alignment of the whole data set. === Image filtering === Image filtering (band-pass filtering) is often used to reduce the influence of high and/or low spatial frequency information in the images, which can affect the results of the alignment and classification procedures. This is particularly useful in negative stain images. The algorithms make use of fast Fourier transforms (FFT), often employing Gaussian shaped soft-edged masks in reciprocal space to suppress certain frequency ranges. High-pass filters remove low spatial frequencies (such as ramp or gradient effects), leaving the higher frequencies intact. Low-pass filters remove high spatial frequency features and have a blurring effect on fine details. === Contrast transfer function === Due to the nature of image formation in the electron microscope, bright-field TEM images are obtained using significant underfocus. This, along with features inherent in the microscope's lens system, creates blurring of the collected images visible as a point spread function. The combined effects of the imaging conditions are known as the contrast transfer function (CTF), and can be approximated mathematically as a function in reciprocal space. Specialized image processing techniques such as phase flipping and amplitude correction / Wiener filtering can (at least partially) correct for the CTF, and allow high resolution reconstructions. === Three-dimensional reconstruction === Transmission electron microscopy images are projections of the object showing the distribution of density through the object, similar to medical X-rays. By making use of the projection-slice theorem a three-dimensional reconstruction of the object can be generated by combining many images (2D projections) of the object taken from a range of viewing angles. Proteins in vitreous ice ideally adopt a random distribution of orientations (or viewing angles), allowing a fairly isotropic reconstruction if a large number of particle images are used. This contrasts with electron tomography, where the viewing angles are limited due to the geometry of the sample/imaging set up, giving an anisotropic reconstruction. Filtered back projection is a commonly used method of generating 3D reconstructions in single particle analysis, although many alternative algorithms exist. Before a reconstruction can be made, the orientation of the object in each image needs to be estimated. Several methods have been developed to work out the relative Euler angles of each image. Some are based on common lines (common 1D projections and sinograms), others use iterative projection matching algorithms. The latter works by beginning with a simple, low resolution 3D starting model and compares the experimental images to projections of the model and creates a new 3D to bootstrap towards a solution. Methods are also available for making 3D reconstructions of helical samples (such as tobacco mosaic virus), taking advantage of the inherent helical symmetry. Both real space methods (treating sections of the helix as single particles) and reciprocal space methods (using diffraction patterns) can be used for these samples. === Tilt methods === The specimen stage of the microscope can be tilted (typically along a single axis), allowing the single particle technique known as random conical tilt. An area of the specimen is imaged at both zero and at high angle (~60-70 degrees) tilts, or in the case of the related method of orthogonal tilt reconstruction, +45 and −45 degrees. Pairs of particles corresponding to the same object at two different tilts (tilt pairs) are selected, and by following the parameters used in subsequent alignment and classification steps a three-dimensional reconstruction can be generated relatively easily. This is because the viewing angle (defined as three Euler angles) of each particle is known from the tilt geometry. 3D reconstructions from random conical tilt suffer from missing information resulting from a restricted range of orientations. Known as the missing cone (due to the shape in reciprocal space), this causes distortions in the 3D maps. However, the missing cone problem can often be overcome by combining several tilt reconstructions. Tilt methods are best suited to negatively stained samples, and can be used for particles that adsorb to the carbon support film in preferred orientations. The phenomenon known as charging or beam-induced movement makes collecting high-tilt images of samples in vitreous ice challenging. === Map visualization and fitting === Various software programs are available that allow viewing the 3D maps. These often enable the user to manually dock in protein coordinates (structures from X-ray crystallography, NMR, or a computational model such as one found in the AlphaFold Protein Structure Database) of subunits into the electron density. Several programs can also fit subunits computationally; as of the 2020s using these programs tend to produce better accuracy than manual docking because they can perform labor-intensive tasks such as: The scale of SPA-derived maps depends on knowing the pixel size (angstorms per pixel), which is not always accurate. Programs can automatically correct for this difference by using coordinate data or by using knowledge of chemical bonds. Many proteins are made up of several roughly rigid protein domains linked by flexible parts. Pre-existing coordinate data, whether experimental or computational, may not exactly match the inter-domain positioning of the cyro-EM map. Modern programs can automatically "chop" pre-existing coordinate data into individual domains and fit them in individually. For higher-resolution structures, it is pos

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  • Zhura

    Zhura

    Zhura ( ZUR-ə) is a free, web-based screenwriting software application for writing and formatting screenplays to the film industry standard, as well as other formats. Zhura allows users to collaborate on scripts in public or private groups and uses Creative Commons Licensing for all work in the public workspace. On March 29, 2010, Zhura announced its merger with Scripped. Scripped's CEO, Sunil Rajaraman, remains the company's Chief Executive Officer (CEO) as of 2022. The Zhura CEO was Eric MacDonald, a former Cascade Communications engineer. Scripped later closed on April 1, 2015 after a catastrophic, irrecoverable data loss. == Script editor == Screenplay Template – The script editor provides a built-in screenplay template which formats the document to a standard for scripts as recommended by the AMPAS. The screenplay document is composed of seven elements: scene, action, character, dialogue, parenthetical, transition, and shot (see image). Each element has a specific style to which the script editor conforms as you type.Script Formats – Other major script formats for stage play, sitcom, audio drama and comic book are also supported as well as the ability to switch between them.Auto-Complete – Characters, scene headings and custom transitions are “remembered” as they are written and “recalled” with tab-completion when a writer starts a new character, scene heading or transition, respectively.Multiple Editors – With a collaborative editing model comparable to Google Docs, two or more users can edit the same script simultaneously, regardless of having a different operating system or web browser. Import/Export – A screenplay written in another program can be imported into the script editor and automatically conformed to the screenplay template. The closer the original script has adhered to the standard format, the better it will appear when imported. Supported import/export formats include Text (.txt) Word (.doc) Rich Text (.rtf) and OpenDocument (.odt). Scripts can also be exported as a PDF file with additional options.Tracking Changes – Similar to the “tracking” feature in Microsoft Word, a user can review all changes made to a script in the revision history as well as highlight the contributions of each writer. Offline Mode – The Google Gears-based offline functionality is in the process of being updated and is not available for new subscribers, according to the company founders. == Community == Scripped supports typical social networking features such as discussion boards, comments, user profiles, public and private writing groups, internal web mail and instant messaging within the script editor. There is also the option to share scripts with others outside of Scripped by making scripts externally viewable. Scripped is made up entirely of user-generated scripts that other users can share, critique and edit, offering creative support to a community of writers. == Licensing of user-created work == There are three types of work-spaces on Scripped (personal, group and public) with unique copyright and licensing management for the work created in each area. Any work a user originates may be moved from the personal area to a public or group area at any time. Once another user edits a script, however, it cannot be moved into the originator’s personal area. Personal Workspace – Any script created or video uploaded in the user’s personal workspace remains copyrighted to that user. Until the user moves that script or video from their personal area into a group or public area, no other user shares a copyright or license to that work. Private Group Workspace – The copyright to any script created or video uploaded in a private group workspace is allocated by the individual members of the group, however they see fit. Public Workspace – Any script created or video uploaded in the public workspace is assigned a Creative Commons license by the originator of that work. The originator of a script may select one of four Creative Commons licenses before introducing that script to the public. The selection of the license is determined by what the author wants to allow others to do with the work. Below is a list of Creative Commons licenses available for all scripts and videos in the public workspace. Share Alike (BY-SA) This license lets others remix, tweak, and build upon your work even for commercial reasons, as long as they credit the original user and license their new creations under the identical terms. This license is often compared to open source software licenses. All new works based on the original user's will carry the same license, so any derivatives will also allow commercial use. No Derivatives (BY-ND) This license allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the original user. Non-Commercial, No Derivatives (BY-NC-ND) This license is the most restrictive of the four licenses, allowing redistribution. This license is often called the "free advertising" license because it allows others to download the original user work and share them with others as long as they mention the original user and link back to them, but they can't change them in any way or use them commercially. Non-Commercial, Share Alike (BY-NC-SA) This license lets others remix, tweak, and build upon the original user's work non-commercially, as long as they credit the original user and license their new creations under the identical terms. Others can download and redistribute the original user's work just like the BY-NC-ND license, but they can also translate, make remixes, and produce new stories based on the original user's work. All new work based on the original user's work will carry the same license, so any derivatives will also be non-commercial in nature. == Events == In April 2008, Zhura partnered with Improv Asylum, a comedy troupe in Boston, Massachusetts to produce a live sketch comedy show called "You Wrote It, Live" entirely written by the public on Zhura. Another show was produced in June.

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  • Caspio

    Caspio

    Caspio, Inc. is an American software company providing a low-code platform for building cloud-based business applications. Founded in 2000 by Frank Zamani, the company is headquartered in Sunnyvale, California, with operations in Poland, the Philippines, and Spain. Caspio’s platform allows organizations to create online database applications and workflow tools without extensive coding. == History == Caspio was founded by Frank Zamani in 2000. The company initially focused on simplifying custom cloud applications and reducing development time and cost as compared to traditional software development. Caspio released the first version of its platform, Caspio Bridge, in 2001. In 2014, Caspio released a HIPAA-Compliant Edition of its low-code application development platform. Caspio also released an EU General Data Protection Regulation (GDPR) Compliance Edition of its low-code application development platform in 2016. Caspio's second European Software Development Center opened in Kraków, Poland in 2017. In 2019, Forrester Research listed Caspio and three other platforms in its highest of four ranked tiers of twelve low-code platforms for business developers based on rankings of offerings and strategy at that time. Caspio also opened data centers in Montreal, Canada and India in 2020.

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