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Agent verification

Agent verification is activity to gain assurances that purposeful artificial constructs act in accordance with their specifications. While primitive forms of inorganic agents have been used in manufacturing for centuries, the study of artificial agents did not begin until the mid 20th century. Foundational work on such agents was closely bound with the emergence of artificial intelligence as an academic discipline. Early agents deployed for industrial control systems and in computing were often controlled by quite simple logic however, not involving artificial intelligence as such. When deployed as part of a multi-agent system, even such simple agents could require special agent orientated testing methods, as their collective behaviour was challenging to verify with traditional testing techniques. Difficulties in providing assurances that agents will not behave in dangerous ways became more prevalent after the introduction of LLM agents, especially after the rapid acceleration of their deployment in 2025. The verification of agent behaviour can be conducted by formal or informal methods. Informal verification requires less mathematical skill. But when agents are part of systems where errors have significant risks — such as danger to human life, environmental damage or major financial loss — formal verification is preferred. Both regulators and system designers themselves like formal verification as it provides a high degree of mathematical certainty. It is not however always possible to formally test all aspects of an agent based system's behaviour, especially where newer LLM based agents are concerned, due in part to their high degree of autonomy. Accordingly, agent verification for low impact deployments might be carried out only with informal methods, while for high impact deployments, it may be performed with a mix of formal and informal techniques. == Terminology == In academia, the term agent verification is often defined to mean activity concerned with gaining assurance that the agent behaves in accordance with its specification - whether by processes such as testing or simulation. 'Verification' is typically contrasted with 'validation', the latter meaning activity concerned with checking that the specification itself meets user or real world needs. Such definitions are not universally adhered to however - for example, in some workplaces and documents, the words 'verification' and 'validation' can be used synonymously. Efforts to gain confidence in Agents have intensified sharply since 2025 due to the rapid roll out of LLM agents; different terms are sometimes used in the commercial sector. Here the term 'agent verification' can be used in the same sense as it is in academia, but sometimes the same activity can be covered by more ambiguous and wider ranging terms such as 'Agent governance' , 'Agent observability' or 'AI agent policing'. == History == === Classical agents === The theoretical underpinnings for artificial (inorganic) agents emerged in the mid 20th century, with establishment of cybernetics and artificial intelligence. Oliver Selfridge's 1958 Pandemonium - A Paradigm for Learning paper was an important early theoretical contribution in establishing agent oriented architecture. Practical implementations of agents for real world applications began to become widespread in the 1990s, after the introduction of the belief–desire–intention software model (BDI), and agent-oriented programming. Pure digital agents were deployed in computer infrastructure for purposes such as monitoring, while agents connected to real-world sensors and actuators were increasingly used in industrial control systems. While the concept of artificial agents was interwoven with early artificial intelligence studies right from the start, early agents lacked general purpose reasoning capabilities, often only having simple if then logic. Even a device as simple as a thermostat, which has a sensor and a means of acting, can be considered a proto agent in this sense. Verifying the behaviours of a simple single agent system is not generally especially difficult, but it can be a different matter when several simple agents coexist in the same system. Craig Reynolds's work on boids showed that relatively complex, "intelligent" behaviour can emerge from a number of such simple agents working together in a Multi-agent system (MAS). By the 1990s, even the behaviour of a single agent system could sometimes be quite complex; in accordance with the Belief–desire–intention software model, agents could have believes that might evolve over time. Agents were increasingly introduced that were controlled by quite large decision tree models, which had new vulnerabilities to adversarial attack. It was becoming increasingly apparent that traditional software verification methods had limitations for testing such agents, or even for the more primitive type of agents when they were deployed as part of a MAS. It was the use of agents for industrial control systems, sometimes associated with robotics, that lent urgency to the practice of agent verification. Informal testing might be acceptable for digital agents used say to monitor whether each of an organisation's computers are properly licensed. But with an increasing potential for faulty agents to result in a failure that might cause a large fire to break out at a chemical manufacturing plant, a botched medical operation, or even a crashed aircraft, the need to develop reliable means of verifying behaviour of such agents was considered urgent. The Foundation for Intelligent Physical Agents was established in 1996. From the late 90s, a growing number of industry and university based scientists began working on the problem, with researchers publishing papers on the verification of both single and multi agent systems. Much of this work showed how formal verification techniques like model checking could be used to gain a high level of assurance that agent based systems would conform with their specification. A 2018 systematic review covering 231 studies found that model checking was the most common technique for agent verification, with theorem proving the second most commonly used formal verification method. In the first two decades of the 20th century, agents run by AI became more common, with Siri and Alexa being well known examples. But such agents still lacked general reasoning capabilities and did not pose new pressing problems for agent verification. === General purpose reasoning agents === The advent of LLMs created huge potential for further use of artificial agents, as agents based on them could have general purpose cognitive abilities. Agents run by LLMs (and occasionally non-LLM foundation models) have similar vulnerability to adversarial attack as those run by decision tree models. The wider scope of actions for LLM agents has created new challenges for their verification, over and above those present for classical agents. For example, the LLM's neural network endows it with infinite domains, an especial challenge for traditional formal verification techniques. Academics began to study the problems involved in verifying LLM agents from 2018. Deployment of such agents began to accelerate in late 2023 after OpenAI's "function-calling" API was made available, and especially after Anthropic's late 2024 introduction of Model Context Protocol (MCP), a standardised way for LLM agents to gain contextual awareness, and to act on the world by calling various external tools. The rapid rollout of LLM agents following MCP's release has seen the task of agent verification receive increased attention within academia, and also from the private sector. In 2024 and 2025 several startups focusing on LLM agent verification have been founded in both Europe and the US to meet growing demand. == Approaches == === Formal verification === Formal verification involves proving the correctness of some or all aspects of a system using mathematical methods. Such methods can range from manual formal proof, to verification assisted with automated theorem provers like Isabelle. For agent verification, model checking is by far the most frequently used formal verification method; for pre-LLM models it was often complemented with techniques using computation tree logic. Another common method is theorem proving. Formal verification provides a higher degree of confidence than informal methods, but it is not always used, even when it is possible. Sometimes a person or organisation developing software agents won't have the necessary skills, or may not see it as worth the effort if the agent(s) will not have the ability to cause much harm even if they malfunction. When agents are deployed in systems where errors could have serious consequences, the ability of formal verification methods to provide mathematical certainty tends to be strongly preferred by both regulators and designers themselves. But even for high impact systems, formal verificatio
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BrownBoost

BrownBoost is a boosting algorithm that may be robust to noisy datasets. BrownBoost is an adaptive version of the boost by majority algorithm. As is the case for all boosting algorithms, BrownBoost is used in conjunction with other machine learning methods. BrownBoost was introduced by Yoav Freund in 2001. == Motivation == AdaBoost performs well on a variety of datasets; however, it can be shown that AdaBoost does not perform well on noisy data sets. This is a result of AdaBoost's focus on examples that are repeatedly misclassified. In contrast, BrownBoost effectively "gives up" on examples that are repeatedly misclassified. The core assumption of BrownBoost is that noisy examples will be repeatedly mislabeled by the weak hypotheses and non-noisy examples will be correctly labeled frequently enough to not be "given up on." Thus only noisy examples will be "given up on," whereas non-noisy examples will contribute to the final classifier. In turn, if the final classifier is learned from the non-noisy examples, the generalization error of the final classifier may be much better than if learned from noisy and non-noisy examples. The user of the algorithm can set the amount of error to be tolerated in the training set. Thus, if the training set is noisy (say 10% of all examples are assumed to be mislabeled), the booster can be told to accept a 10% error rate. Since the noisy examples may be ignored, only the true examples will contribute to the learning process. == Algorithm description == BrownBoost uses a non-convex potential loss function, thus it does not fit into the AdaBoost framework. The non-convex optimization provides a method to avoid overfitting noisy data sets. However, in contrast to boosting algorithms that analytically minimize a convex loss function (e.g. AdaBoost and LogitBoost), BrownBoost solves a system of two equations and two unknowns using standard numerical methods. The only parameter of BrownBoost ( c {\displaystyle c} in the algorithm) is the "time" the algorithm runs. The theory of BrownBoost states that each hypothesis takes a variable amount of time ( t {\displaystyle t} in the algorithm) which is directly related to the weight given to the hypothesis α {\displaystyle \alpha } . The time parameter in BrownBoost is analogous to the number of iterations T {\displaystyle T} in AdaBoost. A larger value of c {\displaystyle c} means that BrownBoost will treat the data as if it were less noisy and therefore will give up on fewer examples. Conversely, a smaller value of c {\displaystyle c} means that BrownBoost will treat the data as more noisy and give up on more examples. During each iteration of the algorithm, a hypothesis is selected with some advantage over random guessing. The weight of this hypothesis α {\displaystyle \alpha } and the "amount of time passed" t {\displaystyle t} during the iteration are simultaneously solved in a system of two non-linear equations ( 1. uncorrelated hypothesis w.r.t example weights and 2. hold the potential constant) with two unknowns (weight of hypothesis α {\displaystyle \alpha } and time passed t {\displaystyle t} ). This can be solved by bisection (as implemented in the JBoost software package) or Newton's method (as described in the original paper by Freund). Once these equations are solved, the margins of each example ( r i ( x j ) {\displaystyle r_{i}(x_{j})} in the algorithm) and the amount of time remaining s {\displaystyle s} are updated appropriately. This process is repeated until there is no time remaining. The initial potential is defined to be 1 m ∑ j = 1 m 1 − erf ( c ) = 1 − erf ( c ) {\displaystyle {\frac {1}{m}}\sum _{j=1}^{m}1-{\mbox{erf}}({\sqrt {c}})=1-{\mbox{erf}}({\sqrt {c}})} . Since a constraint of each iteration is that the potential be held constant, the final potential is 1 m ∑ j = 1 m 1 − erf ( r i ( x j ) / c ) = 1 − erf ( c ) {\displaystyle {\frac {1}{m}}\sum _{j=1}^{m}1-{\mbox{erf}}(r_{i}(x_{j})/{\sqrt {c}})=1-{\mbox{erf}}({\sqrt {c}})} . Thus the final error is likely to be near 1 − erf ( c ) {\displaystyle 1-{\mbox{erf}}({\sqrt {c}})} . However, the final potential function is not the 0–1 loss error function. For the final error to be exactly 1 − erf ( c ) {\displaystyle 1-{\mbox{erf}}({\sqrt {c}})} , the variance of the loss function must decrease linearly w.r.t. time to form the 0–1 loss function at the end of boosting iterations. This is not yet discussed in the literature and is not in the definition of the algorithm below. The final classifier is a linear combination of weak hypotheses and is evaluated in the same manner as most other boosting algorithms. == BrownBoost learning algorithm definition == Input: m {\displaystyle m} training examples ( x 1 , y 1 ) , … , ( x m , y m ) {\displaystyle (x_{1},y_{1}),\ldots ,(x_{m},y_{m})} where x j ∈ X , y j ∈ Y = { − 1 , + 1 } {\displaystyle x_{j}\in X,\,y_{j}\in Y=\{-1,+1\}} The parameter c {\displaystyle c} Initialise: s = c {\displaystyle s=c} . (The value of s {\displaystyle s} is the amount of time remaining in the game) r i ( x j ) = 0 {\displaystyle r_{i}(x_{j})=0} ∀ j {\displaystyle \forall j} . The value of r i ( x j ) {\displaystyle r_{i}(x_{j})} is the margin at iteration i {\displaystyle i} for example x j {\displaystyle x_{j}} . While s > 0 {\displaystyle s>0} : Set the weights of each example: W i ( x j ) = e − ( r i ( x j ) + s ) 2 c {\displaystyle W_{i}(x_{j})=e^{-{\frac {(r_{i}(x_{j})+s)^{2}}{c}}}} , where r i ( x j ) {\displaystyle r_{i}(x_{j})} is the margin of example x j {\displaystyle x_{j}} Find a classifier h i : X → { − 1 , + 1 } {\displaystyle h_{i}:X\to \{-1,+1\}} such that ∑ j W i ( x j ) h i ( x j ) y j > 0 {\displaystyle \sum _{j}W_{i}(x_{j})h_{i}(x_{j})y_{j}>0} Find values α , t {\displaystyle \alpha ,t} that satisfy the equation: ∑ j h i ( x j ) y j e − ( r i ( x j ) + α h i ( x j ) y j + s − t ) 2 c = 0 {\displaystyle \sum _{j}h_{i}(x_{j})y_{j}e^{-{\frac {(r_{i}(x_{j})+\alpha h_{i}(x_{j})y_{j}+s-t)^{2}}{c}}}=0} . (Note this is similar to the condition E W i + 1 [ h i ( x j ) y j ] = 0 {\displaystyle E_{W_{i+1}}[h_{i}(x_{j})y_{j}]=0} set forth by Schapire and Singer. In this setting, we are numerically finding the W i + 1 = exp ⁡ ( ⋯ ⋯ ) {\displaystyle W_{i+1}=\exp \left({\frac {\cdots }{\cdots }}\right)} such that E W i + 1 [ h i ( x j ) y j ] = 0 {\displaystyle E_{W_{i+1}}[h_{i}(x_{j})y_{j}]=0} .) This update is subject to the constraint ∑ ( Φ ( r i ( x j ) + α h ( x j ) y j + s − t ) − Φ ( r i ( x j ) + s ) ) = 0 {\displaystyle \sum \left(\Phi \left(r_{i}(x_{j})+\alpha h(x_{j})y_{j}+s-t\right)-\Phi \left(r_{i}(x_{j})+s\right)\right)=0} , where Φ ( z ) = 1 − erf ( z / c ) {\displaystyle \Phi (z)=1-{\mbox{erf}}(z/{\sqrt {c}})} is the potential loss for a point with margin r i ( x j ) {\displaystyle r_{i}(x_{j})} Update the margins for each example: r i + 1 ( x j ) = r i ( x j ) + α h ( x j ) y j {\displaystyle r_{i+1}(x_{j})=r_{i}(x_{j})+\alpha h(x_{j})y_{j}} Update the time remaining: s = s − t {\displaystyle s=s-t} Output: H ( x ) = sign ( ∑ i α i h i ( x ) ) {\displaystyle H(x)={\textrm {sign}}\left(\sum _{i}\alpha _{i}h_{i}(x)\right)} == Empirical results == In preliminary experimental results with noisy datasets, BrownBoost outperformed AdaBoost's generalization error; however, LogitBoost performed as well as BrownBoost. An implementation of BrownBoost can be found in the open source software JBoost.
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List of text mining software

Text mining computer programs are available from many commercial and open source companies and sources. == Commercial == Angoss – Angoss Text Analytics provides entity and theme extraction, topic categorization, sentiment analysis and document summarization capabilities via the embedded AUTINDEX – is a commercial text mining software package based on sophisticated linguistics by IAI (Institute for Applied Information Sciences), Saarbrücken. DigitalMR – social media listening & text+image analytics tool for market research. FICO Score – leading provider of analytics. General Sentiment – Social Intelligence platform that uses natural language processing to discover affinities between the fans of brands with the fans of traditional television shows in social media. Stand alone text analytics to capture social knowledge base on billions of topics stored to 2004. IBM LanguageWare – the IBM suite for text analytics (tools and Runtime). IBM SPSS – provider of Modeler Premium (previously called IBM SPSS Modeler and IBM SPSS Text Analytics), which contains advanced NLP-based text analysis capabilities (multi-lingual sentiment, event and fact extraction), that can be used in conjunction with Predictive Modeling. Text Analytics for Surveys provides the ability to categorize survey responses using NLP-based capabilities for further analysis or reporting. Inxight – provider of text analytics, search, and unstructured visualization technologies. (Inxight was bought by Business Objects that was bought by SAP AG in 2008). Language Computer Corporation – text extraction and analysis tools, available in multiple languages. Lexalytics – provider of a text analytics engine used in Social Media Monitoring, Voice of Customer, Survey Analysis, and other applications. Salience Engine. The software provides the unique capability of merging the output of unstructured, text-based analysis with structured data to provide additional predictive variables for improved predictive models and association analysis. Linguamatics – provider of natural language processing (NLP) based enterprise text mining and text analytics software, I2E, for high-value knowledge discovery and decision support. Mathematica – provides built in tools for text alignment, pattern matching, clustering and semantic analysis. See Wolfram Language, the programming language of Mathematica. MATLAB offers Text Analytics Toolbox for importing text data, converting it to numeric form for use in machine and deep learning, sentiment analysis and classification tasks. Medallia – offers one system of record for survey, social, text, written and online feedback. NetMiner – software for network analysis and text mining. Supports social media and bibliographic data collection, NLP for english and chinese, sentiment analysis, work co-occurrence network(text network analysis) and visualization. NetOwl – suite of multilingual text and entity analytics products, including entity extraction, link and event extraction, sentiment analysis, geotagging, name translation, name matching, and identity resolution, among others. PolyAnalyst - text analytics environment. PoolParty Semantic Suite - graph-based text mining platform. RapidMiner with its Text Processing Extension – data and text mining software. SAS – SAS Text Miner and Teragram; commercial text analytics, natural language processing, and taxonomy software used for Information Management. Sketch Engine – a corpus manager and analysis software which providing creating text corpora from uploaded texts or the Web including part-of-speech tagging and lemmatization or detecting a particular website. Sysomos – provider social media analytics software platform, including text analytics and sentiment analysis on online consumer conversations. WordStat – Content analysis and text mining add-on module of QDA Miner for analyzing large amounts of text data. == Open source == Carrot2 – text and search results clustering framework. GATE – general Architecture for Text Engineering, an open-source toolbox for natural language processing and language engineering. Gensim – large-scale topic modelling and extraction of semantic information from unstructured text (Python). KH Coder – for Quantitative Content Analysis or Text Mining The KNIME Text Processing extension. Natural Language Toolkit (NLTK) – a suite of libraries and programs for symbolic and statistical natural language processing (NLP) for the Python programming language. OpenNLP – natural language processing. Orange with its text mining add-on. The PLOS Text Mining Collection. The programming language R provides a framework for text mining applications in the package tm. The Natural Language Processing task view contains tm and other text mining library packages. spaCy – open-source Natural Language Processing library for Python Stanbol – an open source text mining engine targeted at semantic content management. Voyant Tools – a web-based text analysis environment, created as a scholarly project.
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Dynamic time warping

In time series analysis, dynamic time warping (DTW) is an algorithm for measuring similarity between two temporal sequences, which may vary in speed. For instance, similarities in walking could be detected using DTW, even if one person was walking faster than the other, or if there were accelerations and decelerations during the course of an observation. DTW has been applied to temporal sequences of video, audio, and graphics data — indeed, any data that can be turned into a one-dimensional sequence can be analyzed with DTW. A well-known application has been automatic speech recognition, to cope with different speaking speeds. Other applications include speaker recognition and online signature recognition. It can also be used in partial shape matching applications. In general, DTW is a method that calculates an optimal match between two given sequences (e.g. time series) with certain restriction and rules: Every index from the first sequence must be matched with one or more indices from the other sequence, and vice versa The first index from the first sequence must be matched with the first index from the other sequence (but it does not have to be its only match) The last index from the first sequence must be matched with the last index from the other sequence (but it does not have to be its only match) The mapping of the indices from the first sequence to indices from the other sequence must be monotonically increasing, and vice versa, i.e. if j > i {\displaystyle j>i} are indices from the first sequence, then there must not be two indices l > k {\displaystyle l>k} in the other sequence, such that index i {\displaystyle i} is matched with index l {\displaystyle l} and index j {\displaystyle j} is matched with index k {\displaystyle k} , and vice versa We can plot each match between the sequences 1 : M {\displaystyle 1:M} and 1 : N {\displaystyle 1:N} as a path in a M × N {\displaystyle M\times N} matrix from ( 1 , 1 ) {\displaystyle (1,1)} to ( M , N ) {\displaystyle (M,N)} , such that each step is one of ( 0 , 1 ) , ( 1 , 0 ) , ( 1 , 1 ) {\displaystyle (0,1),(1,0),(1,1)} . In this formulation, we see that the number of possible matches is the Delannoy number. The optimal match is denoted by the match that satisfies all the restrictions and the rules and that has the minimal cost, where the cost is computed as the sum of absolute differences, for each matched pair of indices, between their values. The sequences are "warped" non-linearly in the time dimension to determine a measure of their similarity independent of certain non-linear variations in the time dimension. This sequence alignment method is often used in time series classification. Although DTW measures a distance-like quantity between two given sequences, it doesn't guarantee the triangle inequality to hold. In addition to a similarity measure between the two sequences (a so called "warping path" is produced), by warping according to this path the two signals may be aligned in time. The signal with an original set of points X(original), Y(original) is transformed to X(warped), Y(warped). This finds applications in genetic sequence and audio synchronisation. In a related technique sequences of varying speed may be averaged using this technique see the average sequence section. This is conceptually very similar to the Needleman–Wunsch algorithm. == Implementation == This example illustrates the implementation of the dynamic time warping algorithm when the two sequences s and t are strings of discrete symbols. For two symbols x and y, d ( x , y ) {\displaystyle d(x,y)} is a distance between the symbols, e.g., d ( x , y ) = | x − y | {\displaystyle d(x,y)=|x-y|} . int DTWDistance(s: array [1..n], t: array [1..m]) { DTW := array [0..n, 0..m] for i := 0 to n for j := 0 to m DTW[i, j] := infinity DTW[0, 0] := 0 for i := 1 to n for j := 1 to m cost := d(s[i], t[j]) DTW[i, j] := cost + minimum(DTW[i-1, j ], // insertion DTW[i , j-1], // deletion DTW[i-1, j-1]) // match return DTW[n, m] } where DTW[i, j] is the distance between s[1:i] and t[1:j] with the best alignment. We sometimes want to add a locality constraint. That is, we require that if s[i] is matched with t[j], then | i − j | {\displaystyle |i-j|} is no larger than w, a window parameter. We can easily modify the above algorithm to add a locality constraint (differences marked). However, the above given modification works only if | n − m | {\displaystyle |n-m|} is no larger than w, i.e. the end point is within the window length from diagonal. In order to make the algorithm work, the window parameter w must be adapted so that | n − m | ≤ w {\displaystyle |n-m|\leq w} (see the line marked with () in the code). int DTWDistance(s: array [1..n], t: array [1..m], w: int) { DTW := array [0..n, 0..m] w := max(w, abs(n-m)) // adapt window size () for i := 0 to n for j:= 0 to m DTW[i, j] := infinity DTW[0, 0] := 0 for i := 1 to n for j := max(1, i-w) to min(m, i+w) DTW[i, j] := 0 for i := 1 to n for j := max(1, i-w) to min(m, i+w) cost := d(s[i], t[j]) DTW[i, j] := cost + minimum(DTW[i-1, j ], // insertion DTW[i , j-1], // deletion DTW[i-1, j-1]) // match return DTW[n, m] } == Warping properties == The DTW algorithm produces a discrete matching between existing elements of one series to another. In other words, it does not allow time-scaling of segments within the sequence. Other methods allow continuous warping. For example, Correlation Optimized Warping (COW) divides the sequence into uniform segments that are scaled in time using linear interpolation, to produce the best matching warping. The segment scaling causes potential creation of new elements, by time-scaling segments either down or up, and thus produces a more sensitive warping than DTW's discrete matching of raw elements. == Complexity == The time complexity of the DTW algorithm is O ( N M ) {\displaystyle O(NM)} , where N {\displaystyle N} and M {\displaystyle M} are the lengths of the two input sequences. The 50 years old quadratic time bound was broken in 2016: an algorithm due to Gold and Sharir enables computing DTW in O ( N 2 / log ⁡ log ⁡ N ) {\displaystyle O({N^{2}}/\log \log N)} time and space for two input sequences of length N {\displaystyle N} . This algorithm can also be adapted to sequences of different lengths. Despite this improvement, it was shown that a strongly subquadratic running time of the form O ( N 2 − ϵ ) {\displaystyle O(N^{2-\epsilon })} for some ϵ > 0 {\displaystyle \epsilon >0} cannot exist unless the Strong exponential time hypothesis fails. While the dynamic programming algorithm for DTW requires O ( N M ) {\displaystyle O(NM)} space in a naive implementation, the space consumption can be reduced to O ( min ( N , M ) ) {\displaystyle O(\min(N,M))} using Hirschberg's algorithm. == Fast computation == Fast techniques for computing DTW include PrunedDTW, SparseDTW, FastDTW, and the MultiscaleDTW. A common task, retrieval of similar time series, can be accelerated by using lower bounds such as LB_Keogh, LB_Improved, or LB_Petitjean. However, the Early Abandon and Pruned DTW algorithm reduces the degree of acceleration that lower bounding provides and sometimes renders it ineffective. In a survey, Wang et al. reported slightly better results with the LB_Improved lower bound than the LB_Keogh bound, and found that other techniques were inefficient. Subsequent to this survey, the LB_Enhanced bound was developed that is always tighter than LB_Keogh while also being more efficient to compute. LB_Petitjean is the tightest known lower bound that can be computed in linear time. == Average sequence == Averaging for dynamic time warping is the problem of finding an average sequence for a set of sequences. NLAAF is an exact method to average two sequences using DTW. For more than two sequences, the problem is related to that of multiple alignment and requires heuristics. DBA is currently a reference method to average a set of sequences consistently with DTW. COMASA efficiently randomizes the search for the average sequence, using DBA as a local optimization process. == Supervised learning == A nearest-neighbour classifier can achieve state-of-the-art performance when using dynamic time warping as a distance measure. == Amerced Dynamic Time Warping == Amerced Dynamic Time Warping (ADTW) is a variant of DTW designed to better control DTW's permissiveness in the alignments that it allows. The windows that classical DTW uses to constrain alignments introduce a step function. Any warping of the path is allowed within the window and none beyond it. In contrast, ADTW employs an additive penalty that is incurred each time that the path is warped. Any amount of warping is allowed, but each warping action incurs a direct penalty. ADTW significantly outperforms DTW with windowing when applied as a nearest neighbor classifier on a set of benchmark time series classification tasks. == Alternative approaches == In functional data analysis, time series are regarde
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Fatsecret

Fatsecret, commonly styled as fatsecret, is a mobile application, website and API that helps people achieve their weight loss goals and find accurate nutrition information. It also offers a weight loss clinic with coaching and medically supported programs. The platform powers global health apps. == History == Fatsecret was founded in 2006 in Melbourne, Australia by Lenny Moses and Rodney Moses. As of 2019, Lenny serves as the company's CEO. The company is known for its calorie counting and meal tracking app, and by April 2016, the company claimed to have 45 million users of its services. In August 2018, a premium version of its app was released. Since August 2009, the company has operated the Fatsecret Platform API, which allows access to its global food and nutrition database. Fatsecret reportedly had 900,000 downloads of its app in January 2020. In an analysis of several Health & Fitness app subcategories for the United States in January 2021, Fatsecret was reported to have the highest 30 day user retention rate of top Calorie Counter + Meal Planner for Weight Loss apps.
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Vanishing gradient problem

In machine learning, the vanishing gradient problem is the problem of greatly diverging gradient magnitudes between earlier and later layers encountered when training neural networks with backpropagation. In such methods, neural network weights are updated proportional to their partial derivative of the loss function. As the number of forward propagation steps in a network increases, for instance due to greater network depth, the gradients of earlier weights are calculated with increasingly many multiplications. These multiplications shrink the gradient magnitude. Consequently, the gradients of earlier weights will be exponentially smaller than the gradients of later weights. This difference in gradient magnitude might introduce instability in the training process, slow it, or halt it entirely. For instance, consider the hyperbolic tangent activation function. The gradients of this function are in range [0,1]. The product of repeated multiplication with such gradients decreases exponentially. The inverse problem, when weight gradients at earlier layers get exponentially larger, is called the exploding gradient problem. Backpropagation allowed researchers to train supervised deep artificial neural networks from scratch, initially with little success. Hochreiter's diplom thesis of 1991 formally identified the reason for this failure in the "vanishing gradient problem", which not only affects many-layered feedforward networks, but also recurrent networks. The latter are trained by unfolding them into very deep feedforward networks, where a new layer is created for each time-step of an input sequence processed by the network (the combination of unfolding and backpropagation is termed backpropagation through time). == Prototypical models == This section is based on the paper On the difficulty of training Recurrent Neural Networks by Pascanu, Mikolov, and Bengio. === Recurrent network model === A generic recurrent network has hidden states h 1 , h 2 , … {\displaystyle h_{1},h_{2},\dots } , inputs u 1 , u 2 , … {\displaystyle u_{1},u_{2},\dots } , and outputs x 1 , x 2 , … {\displaystyle x_{1},x_{2},\dots } . Let it be parameterized by θ {\displaystyle \theta } , so that the system evolves as ( h t , x t ) = F ( h t − 1 , u t , θ ) {\displaystyle (h_{t},x_{t})=F(h_{t-1},u_{t},\theta )} Often, the output x t {\displaystyle x_{t}} is a function of h t {\displaystyle h_{t}} , as some x t = G ( h t ) {\displaystyle x_{t}=G(h_{t})} . The vanishing gradient problem already presents itself clearly when x t = h t {\displaystyle x_{t}=h_{t}} , so we simplify our notation to the special case with: x t = F ( x t − 1 , u t , θ ) {\displaystyle x_{t}=F(x_{t-1},u_{t},\theta )} Now, take its differential: d x t = ∇ θ F ( x t − 1 , u t , θ ) d θ + ∇ x F ( x t − 1 , u t , θ ) d x t − 1 = ∇ θ F ( x t − 1 , u t , θ ) d θ + ∇ x F ( x t − 1 , u t , θ ) [ ∇ θ F ( x t − 2 , u t − 1 , θ ) d θ + ∇ x F ( x t − 2 , u t − 1 , θ ) d x t − 2 ] ⋮ = [ ∇ θ F ( x t − 1 , u t , θ ) + ∇ x F ( x t − 1 , u t , θ ) ∇ θ F ( x t − 2 , u t − 1 , θ ) + ⋯ ] d θ {\displaystyle {\begin{aligned}dx_{t}&=\nabla _{\theta }F(x_{t-1},u_{t},\theta )d\theta +\nabla _{x}F(x_{t-1},u_{t},\theta )dx_{t-1}\\&=\nabla _{\theta }F(x_{t-1},u_{t},\theta )d\theta +\nabla _{x}F(x_{t-1},u_{t},\theta )\left[\nabla _{\theta }F(x_{t-2},u_{t-1},\theta )d\theta +\nabla _{x}F(x_{t-2},u_{t-1},\theta )dx_{t-2}\right]\\&\;\;\vdots \\&=\left[\nabla _{\theta }F(x_{t-1},u_{t},\theta )+\nabla _{x}F(x_{t-1},u_{t},\theta )\nabla _{\theta }F(x_{t-2},u_{t-1},\theta )+\cdots \right]d\theta \end{aligned}}} Training the network requires us to define a loss function to be minimized. Let it be L ( x T , u 1 , … , u T ) {\displaystyle L(x_{T},u_{1},\dots ,u_{T})} , then minimizing it by gradient descent gives Δ θ = − η ⋅ [ ∇ x L ( x T ) ( ∇ θ F ( x t − 1 , u t , θ ) + ∇ x F ( x t − 1 , u t , θ ) ∇ θ F ( x t − 2 , u t − 1 , θ ) + ⋯ ) ] T {\displaystyle \Delta \theta =-\eta \cdot \left[\nabla _{x}L(x_{T})\left(\nabla _{\theta }F(x_{t-1},u_{t},\theta )+\nabla _{x}F(x_{t-1},u_{t},\theta )\nabla _{\theta }F(x_{t-2},u_{t-1},\theta )+\cdots \right)\right]^{T}} where η {\displaystyle \eta } is the learning rate. The vanishing/exploding gradient problem appears because there are repeated multiplications, of the form ∇ x F ( x t − 1 , u t , θ ) ∇ x F ( x t − 2 , u t − 1 , θ ) ∇ x F ( x t − 3 , u t − 2 , θ ) ⋯ {\displaystyle \nabla _{x}F(x_{t-1},u_{t},\theta )\nabla _{x}F(x_{t-2},u_{t-1},\theta )\nabla _{x}F(x_{t-3},u_{t-2},\theta )\cdots } ==== Example: recurrent network with sigmoid activation ==== For a concrete example, consider a typical recurrent network defined by x t = F ( x t − 1 , u t , θ ) = W rec σ ( x t − 1 ) + W in u t + b {\displaystyle x_{t}=F(x_{t-1},u_{t},\theta )=W_{\text{rec}}\sigma (x_{t-1})+W_{\text{in}}u_{t}+b} where θ = ( W rec , W in ) {\displaystyle \theta =(W_{\text{rec}},W_{\text{in}})} is the network parameter, σ {\displaystyle \sigma } is the sigmoid activation function, applied to each vector coordinate separately, and b {\displaystyle b} is the bias vector. Then, ∇ x F ( x t − 1 , u t , θ ) = W rec diag ⁡ ( σ ′ ( x t − 1 ) ) {\displaystyle \nabla _{x}F(x_{t-1},u_{t},\theta )=W_{\text{rec}}\operatorname {diag} (\sigma '(x_{t-1}))} , and so ∇ x F ( x t − 1 , u t , θ ) ∇ x F ( x t − 2 , u t − 1 , θ ) ⋯ ∇ x F ( x t − k , u t − k + 1 , θ ) = W rec diag ⁡ ( σ ′ ( x t − 1 ) ) W rec diag ⁡ ( σ ′ ( x t − 2 ) ) ⋯ W rec diag ⁡ ( σ ′ ( x t − k ) ) {\displaystyle {\begin{aligned}&\nabla _{x}F(x_{t-1},u_{t},\theta )\nabla _{x}F(x_{t-2},u_{t-1},\theta )\cdots \nabla _{x}F(x_{t-k},u_{t-k+1},\theta )\\&=W_{\text{rec}}\operatorname {diag} (\sigma '(x_{t-1}))W_{\text{rec}}\operatorname {diag} (\sigma '(x_{t-2}))\cdots W_{\text{rec}}\operatorname {diag} (\sigma '(x_{t-k}))\end{aligned}}} Since | σ ′ | ≤ 1 {\displaystyle \left|\sigma '\right|\leq 1} , the operator norm of the above multiplication is bounded above by ‖ W rec ‖ k {\displaystyle \left\|W_{\text{rec}}\right\|^{k}} . So if the spectral radius of W rec {\displaystyle W_{\text{rec}}} is γ < 1 {\displaystyle \gamma <1} , then at large k {\displaystyle k} , the above multiplication has operator norm bounded above by γ k → 0 {\displaystyle \gamma ^{k}\to 0} . This is the prototypical vanishing gradient problem. The effect of a vanishing gradient is that the network cannot learn long-range effects. Recall Equation (loss differential): ∇ θ L = ∇ x L ( x T , u 1 , … , u T ) [ ∇ θ F ( x t − 1 , u t , θ ) + ∇ x F ( x t − 1 , u t , θ ) ∇ θ F ( x t − 2 , u t − 1 , θ ) + ⋯ ] {\displaystyle \nabla _{\theta }L=\nabla _{x}L(x_{T},u_{1},\dots ,u_{T})\left[\nabla _{\theta }F(x_{t-1},u_{t},\theta )+\nabla _{x}F(x_{t-1},u_{t},\theta )\nabla _{\theta }F(x_{t-2},u_{t-1},\theta )+\cdots \right]} The components of ∇ θ F ( x , u , θ ) {\displaystyle \nabla _{\theta }F(x,u,\theta )} are just components of σ ( x ) {\displaystyle \sigma (x)} and u {\displaystyle u} , so if u t , u t − 1 , … {\displaystyle u_{t},u_{t-1},\dots } are bounded, then ‖ ∇ θ F ( x t − k − 1 , u t − k , θ ) ‖ {\displaystyle \left\|\nabla _{\theta }F(x_{t-k-1},u_{t-k},\theta )\right\|} is also bounded by some M > 0 {\displaystyle M>0} , and so the terms in ∇ θ L {\displaystyle \nabla _{\theta }L} decay as M γ k {\displaystyle M\gamma ^{k}} . This means that, effectively, ∇ θ L {\displaystyle \nabla _{\theta }L} is affected only by the first O ( γ − 1 ) {\displaystyle O(\gamma ^{-1})} terms in the sum. If γ ≥ 1 {\displaystyle \gamma \geq 1} , the above analysis does not quite work. For the prototypical exploding gradient problem, the next model is clearer. === Dynamical systems model === Following (Doya, 1993), consider this one-neuron recurrent network with sigmoid activation: x t + 1 = ( 1 − ε ) x t + ε σ ( w x t + b ) + ε w ′ u t {\displaystyle x_{t+1}=(1-\varepsilon )x_{t}+\varepsilon \sigma (wx_{t}+b)+\varepsilon w'u_{t}} At the small ε {\displaystyle \varepsilon } limit, the dynamics of the network becomes d x d t = − x ( t ) + σ ( w x ( t ) + b ) + w ′ u ( t ) {\displaystyle {\frac {dx}{dt}}=-x(t)+\sigma (wx(t)+b)+w'u(t)} Consider first the autonomous case, with u = 0 {\displaystyle u=0} . Set w = 5.0 {\displaystyle w=5.0} , and vary b {\displaystyle b} in [ − 3 , − 2 ] {\displaystyle [-3,-2]} . As b {\displaystyle b} decreases, the system has 1 stable point, then has 2 stable points and 1 unstable point, and finally has 1 stable point again. Explicitly, the stable points are ( x , b ) = ( x , ln ⁡ ( x 1 − x ) − 5 x ) {\displaystyle (x,b)=\left(x,\ln \left({\frac {x}{1-x}}\right)-5x\right)} . Now consider Δ x ( T ) Δ x ( 0 ) {\displaystyle {\frac {\Delta x(T)}{\Delta x(0)}}} and Δ x ( T ) Δ b {\displaystyle {\frac {\Delta x(T)}{\Delta b}}} , where T {\displaystyle T} is large enough that the system has settled into one of the stable points. If ( x ( 0 ) , b ) {\displaystyle (x(0),b)} puts the system very close to an unstable point, then a tiny variation in x ( 0 ) {\displaystyle x(0)} or b {\displaystyle b} wo
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KXEN Inc.

KXEN was an American software company which existed from 1998 to 2013 when it was acquired by SAP AG. == History == KXEN was founded in June 1998 by Roger Haddad and Michel Bera. It was based in San Francisco, California with offices in Paris and London. On September 10, 2013, SAP AG announced plans to acquire KXEN. On October 1, 2013, a letter to KXEN customers announced the acquisition closed. KXEN primarily marketed predictive analytics software. == Predictive analytics == InfiniteInsight is a predictive modeling suite developed by KXEN that assists analytic professionals, and business executives to extract information from data. Among other functions, InfiniteInsight is used for variable importance, classification, regression, segmentation, time series, product recommendation, as described and expressed by the Java Data Mining interface, and for social network analysis. InfiniteInsight allows prediction of a behavior or a value, the forecast of a time series or the understanding of a group of individuals with similar behavior. Advanced functions include behavioral modeling, exporting the model code into different target environments or building predictive models on top of SAS or SPSS data files. Competitors are SAS Enterprise Miner, IBM SPSS Modeler, and Statistica. Open source predictive tools like the R package or Weka are also competitors, since they provide similar features free of charge.
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Spiking neural network

Spiking neural networks (SNNs) are artificial neural networks (ANN) that mimic natural neural networks. These models leverage timing of discrete spikes as the main information carrier. In addition to neuronal and synaptic state, SNNs incorporate the concept of time into their operating model. The idea is that neurons in the SNN do not transmit information at each propagation cycle (as it happens with typical multi-layer perceptron networks), but rather transmit information only when a membrane potential—an intrinsic quality of the neuron related to its membrane electrical charge—reaches a specific value, called the threshold. When the membrane potential reaches the threshold, the neuron fires, and generates a signal that travels to other neurons which, in turn, increase or decrease their potentials in response to this signal. A neuron model that fires at the moment of threshold crossing is also called a spiking neuron model. While spike rates can be considered the analogue of the variable output of a traditional ANN, neurobiology research indicated that high speed processing cannot be performed solely through a rate-based scheme. For example humans can perform an image recognition task requiring no more than 10ms of processing time per neuron through the successive layers (going from the retina to the temporal lobe). This time window is too short for rate-based encoding. The precise spike timings in a small set of spiking neurons also has a higher information coding capacity compared with a rate-based approach. The most prominent spiking neuron model is the leaky integrate-and-fire model. In that model, the momentary activation level (modeled as a differential equation) is normally considered to be the neuron's state, with incoming spikes pushing this value higher or lower, until the state eventually either decays or—if the firing threshold is reached—the neuron fires. After firing, the state variable is reset to a lower value. Various decoding methods exist for interpreting the outgoing spike train as a real-value number, relying on either the frequency of spikes (rate-code), the time-to-first-spike after stimulation, or the interval between spikes. == History == Many multi-layer artificial neural networks are fully connected, receiving input from every neuron in the previous layer and signalling every neuron in the subsequent layer. Although these networks have achieved breakthroughs, they do not match biological networks and do not mimic neurons. The biology-inspired Hodgkin–Huxley model of a spiking neuron was proposed in 1952. This model described how action potentials are initiated and propagated. Communication between neurons, which requires the exchange of chemical neurotransmitters in the synaptic gap, is described in models such as the integrate-and-fire model, FitzHugh–Nagumo model (1961–1962), and Hindmarsh–Rose model (1984). The leaky integrate-and-fire model (or a derivative) is commonly used as it is easier to compute than Hodgkin–Huxley. While the notion of an artificial spiking neural network became popular only in the twenty-first century, studies between 1980 and 1995 supported the concept. The first models of this type of ANN appeared to simulate non-algorithmic intelligent information processing systems. However, the notion of the spiking neural network as a mathematical model was first worked on in the early 1970s. As of 2019 SNNs lagged behind ANNs in accuracy, but the gap is decreasing, and has vanished on some tasks. == Underpinnings == Information in the brain is represented as action potentials (neuron spikes), which may group into spike trains or coordinated waves. A fundamental question of neuroscience is to determine whether neurons communicate by a rate or temporal code. Temporal coding implies that a single spiking neuron can replace hundreds of hidden units on a conventional neural net. SNNs define a neuron's current state as its potential (possibly modeled as a differential equation). An input pulse causes the potential to rise and then gradually decline. Encoding schemes can interpret these pulse sequences as a number, considering pulse frequency and pulse interval. Using the precise time of pulse occurrence, a neural network can consider more information and offer better computing properties. SNNs compute in the continuous domain. Such neurons test for activation only when their potentials reach a certain value. When a neuron is activated, it produces a signal that is passed to connected neurons, accordingly raising or lowering their potentials. The SNN approach produces a continuous output instead of the binary output of traditional ANNs. Pulse trains are not easily interpretable, hence the need for encoding schemes. However, a pulse train representation may be more suited for processing spatiotemporal data (or real-world sensory data classification). SNNs connect neurons only to nearby neurons so that they process input blocks separately (similar to CNN using filters). They consider time by encoding information as pulse trains so as not to lose information. This avoids the complexity of a recurrent neural network (RNN). Impulse neurons are more powerful computational units than traditional artificial neurons. SNNs are theoretically more powerful than so called "second-generation networks" defined as ANNs "based on computational units that apply activation function with a continuous set of possible output values to a weighted sum (or polynomial) of the inputs"; however, SNN training issues and hardware requirements limit their use. Although unsupervised biologically inspired learning methods are available such as Hebbian learning and STDP, no effective supervised training method is suitable for SNNs that can provide better performance than second-generation networks. Spike-based activation of SNNs is not differentiable, thus gradient descent-based backpropagation (BP) is not available. SNNs have much larger computational costs for simulating realistic neural models than traditional ANNs. Pulse-coupled neural networks (PCNN) are often confused with SNNs. A PCNN can be seen as a kind of SNN. Researchers are actively working on various topics. The first concerns differentiability. The expressions for both the forward- and backward-learning methods contain the derivative of the neural activation function which is not differentiable because a neuron's output is either 1 when it spikes, and 0 otherwise. This all-or-nothing behavior disrupts gradients and makes these neurons unsuitable for gradient-based optimization. Approaches to resolving it include: resorting to entirely biologically inspired local learning rules for the hidden units translating conventionally trained "rate-based" NNs to SNNs smoothing the network model to be continuously differentiable defining an SG (Surrogate Gradient) as a continuous relaxation of the real gradients The second concerns the optimization algorithm. Standard BP can be expensive in terms of computation, memory, and communication and may be poorly suited to the hardware that implements it (e.g., a computer, brain, or neuromorphic device). Incorporating additional neuron dynamics such as Spike Frequency Adaptation (SFA) is a notable advance, enhancing efficiency and computational power. These neurons sit between biological complexity and computational complexity. Originating from biological insights, SFA offers significant computational benefits by reducing power usage, especially in cases of repetitive or intense stimuli. This adaptation improves signal/noise clarity and introduces an elementary short-term memory at the neuron level, which in turn, improves accuracy and efficiency. This was mostly achieved using compartmental neuron models. The simpler versions are of neuron models with adaptive thresholds, are an indirect way of achieving SFA. It equips SNNs with improved learning capabilities, even with constrained synaptic plasticity, and elevates computational efficiency. This feature lessens the demand on network layers by decreasing the need for spike processing, thus lowering computational load and memory access time—essential aspects of neural computation. Moreover, SNNs utilizing neurons capable of SFA achieve levels of accuracy that rival those of conventional ANNs, while also requiring fewer neurons for comparable tasks. This efficiency streamlines the computational workflow and conserves space and energy, while maintaining technical integrity. High-performance deep spiking neural networks can operate with 0.3 spikes per neuron. == Applications == SNNs can in principle be applied to the same applications as traditional ANNs. In addition, SNNs can model the central nervous system of biological organisms, such as an insect seeking food without prior knowledge of the environment. Due to their relative realism, they can be used to study biological neural circuits. Starting with a hypothesis about the topology of a biological neuronal circuit and its functi
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Spike (application)

Spike is a cross-platform email client and AI-powered communication app, available on Windows, MacOS, iOS, Android and the web. It has a chat-like, conversational view for emails with AI-powered inbox management and integrated collaboration features. Depending on the selected plan, it can be used solely as an email application or as a full suite of business communication tools. == History == Founded in 2013 by Erez Pilosof and Dvir Ben-Aroya, Spike is a software application that puts existing e-mails into a multimedia messaging, chat-like interface enhanced with video and voice calls. The application was initially named Hop. In 2019, the developers completed a $5 million funding round including investment from Wix.com and NFX Capital. In 2020, Spike raised $8m in a Series A funding round led by Insight Partners with the participation from previous rounds' investors. In 2021 Spike announced a collaboration with Meta to launch on the Oculus Store and would become one of the first productivity apps to launch in Meta's new virtual world, known as the Metaverse. In June 2023, the company introduced its corporate offering — Teamspace, a corporate communication platform for teams with features such as company-wide channels for broad conversations, private groups for specific topics or projects, direct one-on-one conversations, video meetings, file collaboration, AI-powered email messaging, and custom email domain. It supports file management, search capabilities, and project management. Built on open-protocol technology, Spike Teamspace enables users to send and receive messages from all email providers. Regardless of whether the other party is using Spike. == Company operations == Spike is developed and operated by SpikeNow LTD. Dvir Ben Aroya serves as Spike’s CEO and Erez Pilosof is the CTO. The company is headquartered in Tel Aviv, Israel. == Mode of use == The app enables users to organize email into three types of "conversations,"a traditional inbox/sent format, by subject, or by people. Spike users can also make audio and video calls to each other, and other features include a calendar, contact list, and Groups. Spike is available for Microsoft Windows, MacOS, iOS and Android, and as a web version, and works with Gmail, Outlook, Exchange, iCloud, Yahoo! Mail and IMAP email providers. == Features == Since 2023, the platform features an AI-driven assistant, Magic AI, for customized email creation, document summarization, research, content generation, advanced note-taking, project management, and real-time translation. Since 2023, Spike offers custom email domain management. It supports team collaboration through Channels, uniting members globally with access to historical messages, and combines email with real-time messaging via Conversational Email. The Shared Inbox allows team collaboration on emails, while Groups support private conversations and invitations. It also features integrated video meetings, real-time collaboration on documents and notes, and email hosting with custom domains. Super Search enables retrieval of various content, and the Priority Inbox organizes emails by priority. Collaborative Tasks offer real-time updates and tracking. The platform allows voice message sending from mobile devices and integrates multiple calendar platforms into a unified schedule. File Management optimizes attachment handling, and the Unified Inbox consolidates emails from multiple accounts. Spike ensures data security with AES-256 encryption and private keys. The platform features AI-powered inbox management and communication tools. In May 2025, Spike launched its AI Feed feature, which automatically summarizes unread messages in a unified stream and enables bulk email actions. Additional AI capabilities include email composition assistance, document summarization, content generation, note-taking enhancement, and real-time translation.
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Bioz

Bioz is a search engine for life science experimentation. == History == Bioz was founded by Karin Lachmi and Daniel Levitt. Lachmi is a scientist who completed her postdoc in molecular and cellular biology at the Stanford University School of Medicine. During her lab work she found little available data regarding preferable lab tools, reagents and related products for experimentation. There are 50,000 vendors selling 300 million scientific products. She decided to start the company in order to provide researchers with adequate information for that purpose. Co-founder Daniel Levitt is an entrepreneur who sold his company WebAppoint to Microsoft in the year 2000. He also co-founded the company StemRad. At Bioz, Lachmi serves as the Chief Scientific Officer and Levitt serves as the chief executive officer. Bioz claims to have over a million researcher-users from 196 countries. Among the investors are Esther Dyson and the Stanford-StartX Fund. The company's advisory board includes Nobel Laureates in Chemistry Michael Levitt, Roger Kornberg, and Ada Yonath. == Technology == The company uses artificial intelligence, machine learning and natural language processing in order to extract experimentation data from scientific articles, such as the products that researchers used, the companies that supply the products, the protocol conditions that researchers selected, and the types of experiments and techniques. The algorithm ranks products based on how frequently they were used by researchers in their experiments, how recently a product was used, and the impact factor of the journal. The algorithm's output is a Bioz stars score for each product that was mentioned in an article. Bioz is a data-driven platform for product recommendations, which is contrary to platforms such as TripAdvisor and OpenTable that are based on user-generated reviews and ratings. The recommendations and scoring system that the company has developed are meant to assist researchers with the process of developing future medications and finding cures for diseases. They are guided towards products and techniques that were previously used by other researchers when planning and performing experiments. The company's revenue is based on selling SaaS subscriptions to researchers in biopharma companies. They also charge product suppliers for content syndication.
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ImageNets

ImageNets is an open source framework for rapid prototyping of machine vision algorithms, developed by the Institute of Automation. == Description == ImageNets is an open source and platform independent (Windows & Linux) framework for rapid prototyping of machine vision algorithms. With the GUI ImageNet Designer, no programming knowledge is required to perform operations on images. A configured ImageNet can be loaded and executed from C++ code without the need for loading the ImageNet Designer GUI to achieve higher execution performance. == History == ImageNets was developed by the Institute of Automation, University of Bremen, Germany. The software was first publicly released in 2010. Originally, ImageNets was developed for the Care-Providing Robot FRIEND but it can be used for a wide range of computer vision applications.
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Low-rank approximation

In mathematics, low-rank approximation refers to the process of approximating a given matrix by a matrix of lower rank. More precisely, it is a minimization problem, in which the cost function measures the fit between a given matrix (the data) and an approximating matrix (the optimization variable), subject to a constraint that the approximating matrix has reduced rank. The problem is used for mathematical modeling and data compression. The rank constraint is related to a constraint on the complexity of a model that fits the data. In applications, often there are other constraints on the approximating matrix apart from the rank constraint, e.g., non-negativity and Hankel structure. Low-rank approximation is closely related to numerous other techniques, including principal component analysis, factor analysis, total least squares, latent semantic analysis, orthogonal regression, and dynamic mode decomposition. == Definition == Given structure specification S : R n p → R m × n {\displaystyle {\mathcal {S}}:\mathbb {R} ^{n_{p}}\to \mathbb {R} ^{m\times n}} , vector of structure parameters p ∈ R n p {\displaystyle p\in \mathbb {R} ^{n_{p}}} , norm ‖ ⋅ ‖ {\displaystyle \|\cdot \|} , and desired rank r {\displaystyle r} , minimize over p ^ ‖ p − p ^ ‖ subject to rank ⁡ ( S ( p ^ ) ) ≤ r . {\displaystyle {\text{minimize}}\quad {\text{over }}{\widehat {p}}\quad \|p-{\widehat {p}}\|\quad {\text{subject to}}\quad \operatorname {rank} {\big (}{\mathcal {S}}({\widehat {p}}){\big )}\leq r.} == Applications == Linear system identification, in which case the approximating matrix is Hankel structured. Machine learning, in which case the approximating matrix is nonlinearly structured. Recommender systems, in which cases the data matrix has missing values and the approximation is categorical. Distance matrix completion, in which case there is a positive definiteness constraint. Natural language processing, in which case the approximation is nonnegative. Computer algebra, in which case the approximation is Sylvester structured. Matrix product states, in which case the approximation is usually rescaled to have fixed Frobenius norm. == Basic low-rank approximation problem == The unstructured problem with fit measured by the Frobenius norm, i.e., minimize over D ^ ‖ D − D ^ ‖ F subject to rank ⁡ ( D ^ ) ≤ r {\displaystyle {\text{minimize}}\quad {\text{over }}{\widehat {D}}\quad \|D-{\widehat {D}}\|_{\text{F}}\quad {\text{subject to}}\quad \operatorname {rank} {\big (}{\widehat {D}}{\big )}\leq r} has an analytic solution in terms of the singular value decomposition of the data matrix. The result is referred to as the matrix approximation lemma or Eckart–Young–Mirsky theorem. This problem was originally solved by Erhard Schmidt in the infinite dimensional context of integral operators (although his methods easily generalize to arbitrary compact operators on Hilbert spaces) and later rediscovered by C. Eckart and G. Young. L. Mirsky generalized the result to arbitrary unitarily invariant norms. Let D = U Σ V ⊤ ∈ R m × n , m ≥ n {\displaystyle D=U\Sigma V^{\top }\in \mathbb {R} ^{m\times n},\quad m\geq n} be the singular value decomposition of D {\displaystyle D} , where Σ =: diag ⁡ ( σ 1 , … , σ r ) {\displaystyle \Sigma =:\operatorname {diag} (\sigma _{1},\ldots ,\sigma _{r})} , where r ≤ min { m , n } = n {\displaystyle r\leq \min\{m,n\}=n} , is the m × n {\displaystyle m\times n} rectangular diagonal matrix with r {\displaystyle r} non-zero singular values σ 1 ≥ … ≥ σ r > σ r + 1 = … = σ n = 0 {\displaystyle \sigma _{1}\geq \ldots \geq \sigma _{r}>\sigma _{r+1}=\ldots =\sigma _{n}=0} . For a given k ∈ { 1 , … , r } {\displaystyle k\in \{1,\dots ,r\}} , partition U {\displaystyle U} , Σ {\displaystyle \Sigma } , and V {\displaystyle V} as follows: U =: [ U 1 U 2 ] , Σ =: [ Σ 1 0 0 Σ 2 ] , and V =: [ V 1 V 2 ] , {\displaystyle U=:{\begin{bmatrix}U_{1}&U_{2}\end{bmatrix}},\quad \Sigma =:{\begin{bmatrix}\Sigma _{1}&0\\0&\Sigma _{2}\end{bmatrix}},\quad {\text{and}}\quad V=:{\begin{bmatrix}V_{1}&V_{2}\end{bmatrix}},} where U 1 {\displaystyle U_{1}} is m × k {\displaystyle m\times k} , Σ 1 {\displaystyle \Sigma _{1}} is k × k {\displaystyle k\times k} , and V 1 {\displaystyle V_{1}} is n × k {\displaystyle n\times k} . Then the rank k {\displaystyle k} matrix D ^ ∗ := U 1 Σ 1 V 1 ⊤ , {\displaystyle {\widehat {D}}^{}:=U_{1}\Sigma _{1}V_{1}^{\top },} obtained from the truncated singular value decomposition is such that ‖ D − D ^ ∗ ‖ F = min rank ⁡ ( D ^ ) ≤ k ‖ D − D ^ ‖ F = σ k + 1 2 + ⋯ + σ r 2 . {\displaystyle \|D-{\widehat {D}}^{}\|_{\text{F}}=\min _{\operatorname {rank} ({\widehat {D}})\leq k}\|D-{\widehat {D}}\|_{\text{F}}={\sqrt {\sigma _{k+1}^{2}+\cdots +\sigma _{r}^{2}}}.} The minimizer D ^ ∗ {\displaystyle {\widehat {D}}^{}} is unique if and only if σ k > σ k + 1 {\displaystyle \sigma _{k}>\sigma _{k+1}} . == Proof of Eckart–Young–Mirsky theorem (for spectral norm) == Let A ∈ R m × n {\displaystyle A\in \mathbb {R} ^{m\times n}} be a real (possibly rectangular) matrix with m ≤ n {\displaystyle m\leq n} . Suppose that A = U Σ V ⊤ {\displaystyle A=U\Sigma V^{\top }} is the singular value decomposition of A {\displaystyle A} . Recall that U {\displaystyle U} and V {\displaystyle V} are orthogonal matrices, and Σ {\displaystyle \Sigma } is an m × n {\displaystyle m\times n} diagonal matrix with entries ( σ 1 , σ 2 , ⋯ , σ m ) {\displaystyle (\sigma _{1},\sigma _{2},\cdots ,\sigma _{m})} such that σ 1 ≥ σ 2 ≥ ⋯ ≥ σ m ≥ 0 {\displaystyle \sigma _{1}\geq \sigma _{2}\geq \cdots \geq \sigma _{m}\geq 0} . We claim that the best rank- k {\displaystyle k} approximation to A {\displaystyle A} in the spectral norm, denoted by ‖ ⋅ ‖ 2 {\displaystyle \|\cdot \|_{2}} , is given by A k := ∑ i = 1 k σ i u i v i ⊤ {\displaystyle A_{k}:=\sum _{i=1}^{k}\sigma _{i}u_{i}v_{i}^{\top }} where u i {\displaystyle u_{i}} and v i {\displaystyle v_{i}} denote the i {\displaystyle i} th column of U {\displaystyle U} and V {\displaystyle V} , respectively. First, note that we have ‖ A − A k ‖ 2 = ‖ ∑ i = 1 n σ i u i v i ⊤ − ∑ i = 1 k σ i u i v i ⊤ ‖ 2 = ‖ ∑ i = k + 1 n σ i u i v i ⊤ ‖ 2 = σ k + 1 {\displaystyle \|A-A_{k}\|_{2}=\left\|\sum _{i=1}^{\color {red}{n}}\sigma _{i}u_{i}v_{i}^{\top }-\sum _{i=1}^{\color {red}{k}}\sigma _{i}u_{i}v_{i}^{\top }\right\|_{2}=\left\|\sum _{i=\color {red}{k+1}}^{n}\sigma _{i}u_{i}v_{i}^{\top }\right\|_{2}=\sigma _{k+1}} Therefore, we need to show that if B k = X Y ⊤ {\displaystyle B_{k}=XY^{\top }} where X {\displaystyle X} and Y {\displaystyle Y} have k {\displaystyle k} columns then ‖ A − A k ‖ 2 = σ k + 1 ≤ ‖ A − B k ‖ 2 {\displaystyle \|A-A_{k}\|_{2}=\sigma _{k+1}\leq \|A-B_{k}\|_{2}} . Since Y {\displaystyle Y} has k {\displaystyle k} columns, then there must be a nontrivial linear combination of the first k + 1 {\displaystyle k+1} columns of V {\displaystyle V} , i.e., w = γ 1 v 1 + ⋯ + γ k + 1 v k + 1 , {\displaystyle w=\gamma _{1}v_{1}+\cdots +\gamma _{k+1}v_{k+1},} such that Y ⊤ w = 0 {\displaystyle Y^{\top }w=0} . Without loss of generality, we can scale w {\displaystyle w} so that ‖ w ‖ 2 = 1 {\displaystyle \|w\|_{2}=1} or (equivalently) γ 1 2 + ⋯ + γ k + 1 2 = 1 {\displaystyle \gamma _{1}^{2}+\cdots +\gamma _{k+1}^{2}=1} . Therefore, ‖ A − B k ‖ 2 2 ≥ ‖ ( A − B k ) w ‖ 2 2 = ‖ A w ‖ 2 2 = γ 1 2 σ 1 2 + ⋯ + γ k + 1 2 σ k + 1 2 ≥ σ k + 1 2 . {\displaystyle \|A-B_{k}\|_{2}^{2}\geq \|(A-B_{k})w\|_{2}^{2}=\|Aw\|_{2}^{2}=\gamma _{1}^{2}\sigma _{1}^{2}+\cdots +\gamma _{k+1}^{2}\sigma _{k+1}^{2}\geq \sigma _{k+1}^{2}.} The result follows by taking the square root of both sides of the above inequality. == Proof of Eckart–Young–Mirsky theorem (for Frobenius norm) == Let A ∈ R m × n {\displaystyle A\in \mathbb {R} ^{m\times n}} be a real (possibly rectangular) matrix with m ≤ n {\displaystyle m\leq n} . Suppose that A = U Σ V ⊤ {\displaystyle A=U\Sigma V^{\top }} is the singular value decomposition of A {\displaystyle A} . We claim that the best rank k {\displaystyle k} approximation to A {\displaystyle A} in the Frobenius norm, denoted by ‖ ⋅ ‖ F {\displaystyle \|\cdot \|_{F}} , is given by A k = ∑ i = 1 k σ i u i v i ⊤ {\displaystyle A_{k}=\sum _{i=1}^{k}\sigma _{i}u_{i}v_{i}^{\top }} where u i {\displaystyle u_{i}} and v i {\displaystyle v_{i}} denote the i {\displaystyle i} th column of U {\displaystyle U} and V {\displaystyle V} , respectively. First, note that we have ‖ A − A k ‖ F 2 = ‖ ∑ i = k + 1 n σ i u i v i ⊤ ‖ F 2 = ∑ i = k + 1 n σ i 2 {\displaystyle \|A-A_{k}\|_{F}^{2}=\left\|\sum _{i=k+1}^{n}\sigma _{i}u_{i}v_{i}^{\top }\right\|_{F}^{2}=\sum _{i=k+1}^{n}\sigma _{i}^{2}} Therefore, we need to show that if B k = X Y ⊤ {\displaystyle B_{k}=XY^{\top }} where X {\displaystyle X} and Y {\displaystyle Y} have k {\displaystyle k} columns then ‖ A − A k ‖ F 2 = ∑ i = k + 1 n σ i 2 ≤ ‖ A − B k ‖ F 2 . {\displaystyle \|A-A_{k}\|_{F}^{2}=\sum _{i=k+1}^{n}\sigma _{i}^{2}\leq \|A-B_{k}\|_{F}^{2}.} By the triangle inequality with the spectral norm
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Region Based Convolutional Neural Networks

Region-based Convolutional Neural Networks (R-CNN) are a family of machine learning models for computer vision, and specifically object detection and localization. The original goal of R-CNN was to take an input image and produce a set of bounding boxes as output, where each bounding box contains an object and also the category (e.g. car or pedestrian) of the object. In general, R-CNN architectures perform selective search over feature maps outputted by a CNN. R-CNN has been extended to perform other computer vision tasks, such as: tracking objects from a drone-mounted camera, locating text in an image, and enabling object detection in Google Lens. Mask R-CNN is also one of seven tasks in the MLPerf Training Benchmark, which is a competition to speed up the training of neural networks. == History == The following covers some of the versions of R-CNN that have been developed. November 2013: R-CNN. April 2015: Fast R-CNN. June 2015: Faster R-CNN. March 2017: Mask R-CNN. December 2017: Cascade R-CNN is trained with increasing Intersection over Union (IoU, also known as the Jaccard index) thresholds, making each stage more selective against nearby false positives. June 2019: Mesh R-CNN adds the ability to generate a 3D mesh from a 2D image. == Architecture == For review articles see. === Selective search === Given an image (or an image-like feature map), selective search (also called Hierarchical Grouping) first segments the image by the algorithm in (Felzenszwalb and Huttenlocher, 2004), then performs the following: Input: (colour) image Output: Set of object location hypotheses L Segment image into initial regions R = {r1, ..., rn} using Felzenszwalb and Huttenlocher (2004) Initialise similarity set S = ∅ foreach Neighbouring region pair (ri, rj) do Calculate similarity s(ri, rj) S = S ∪ s(ri, rj) while S ≠ ∅ do Get highest similarity s(ri, rj) = max(S) Merge corresponding regions rt = ri ∪ rj Remove similarities regarding ri: S = S \ s(ri, r∗) Remove similarities regarding rj: S = S \ s(r∗, rj) Calculate similarity set St between rt and its neighbours S = S ∪ St R = R ∪ rt Extract object location boxes L from all regions in R === R-CNN === With R-CNN, prediction follows a two-step process. A preprocessing selective search step generates a large set of candidate objects (typically as many as 2000), known as regions of interest (ROI). These are forwarded to a CNN, which predicts an object class score and bounding box estimate, independently for each ROI. Importantly, the ROIs are heavily filtered to remove excess candidates. This is achieved using two mechanism. Filtering begins by removing ROIs assigned to the background category. This is a specialized category, which is scored by the CNN alongside other categories. An unfortunate reality is that remaining ROIs typically suffer from heavy duplication. Namely, multiple ROIs that cover same objects in the image are all assigned non-background categories. This is resolved by a heuristic non-maximum suppression (NMS) step. === Fast R-CNN === While the original R-CNN independently computed the neural network features on each of as many as two thousand regions of interest, Fast R-CNN runs the neural network once on the whole image. At the end of the network is a ROIPooling module, which slices out each ROI from the network's output tensor, reshapes it, and classifies it. As in the original R-CNN, the Fast R-CNN uses selective search to generate its region proposals. === Faster R-CNN === While Fast R-CNN used selective search to generate ROIs, Faster R-CNN integrates the ROI generation into the neural network itself. === Mask R-CNN === While previous versions of R-CNN focused on object detections, Mask R-CNN adds instance segmentation. Mask R-CNN also replaced ROIPooling with a new method called ROIAlign, which can represent fractions of a pixel.
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Pruning (artificial neural network)

In deep learning, pruning is the practice of removing parameters from an existing artificial neural network. The goal of this process is to reduce the size (parameter count) of the neural network (and therefore the computational resources required to run it) whilst maintaining accuracy. This can be compared to the biological process of synaptic pruning which takes place in mammalian brains during development. == Node (neuron) pruning == A basic algorithm for pruning is as follows: Evaluate the importance of each neuron. Rank the neurons according to their importance (assuming there is a clearly defined measure for "importance"). Remove the least important neuron. Check a termination condition (to be determined by the user) to see whether to continue pruning. == Edge (weight) pruning == Most work on neural network pruning does not remove full neurons or layers (structured pruning). Instead, it focuses on removing the most insignificant weights (unstructured pruning), namely, setting their values to zero. This can either be done globally by comparing weights from all layers in the network or locally by comparing weights in each layer separately. Different metrics can be used to measure the importance of each weight. Weight magnitude as well as combinations of weight and gradient information are commonly used metrics. Early work suggested also to change the values of non-pruned weights. == When to prune the neural network? == Pruning can be applied at three different stages: before training, during training, or after training. When pruning is performed during or after training, additional fine-tuning epochs are typically required. Each approach involves different trade-offs between accuracy and computational cost.
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Causal Markov condition

The Causal Markov (CM) condition states that, conditional on the set of all its direct causes, a node is independent of all variables which are not effects or direct causes of that node. In the event that the structure of a Bayesian network accurately depicts causality, the two conditions are equivalent. This is related to the Markov condition, an assumption made in Bayesian probability theory, that every node in a Bayesian network is conditionally independent of its nondescendants, given its parents. Stated loosely, it is assumed that a node has no bearing on nodes which do not descend from it. In a DAG, this local Markov condition is equivalent to the global Markov condition, which states that d-separations in the graph also correspond to conditional independence relations. This also means that a node is conditionally independent of the entire network, given its Markov blanket. A network may accurately embody the Markov condition without depicting causality, in which case it should not be assumed to embody the causal Markov condition. == Motivation == Statisticians are enormously interested in the ways in which certain events and variables are connected. The precise notion of what constitutes a cause and effect is necessary to understand the connections between them. The central idea behind the philosophical study of probabilistic causation is that causes raise the probabilities of their effects, all else being equal. A deterministic interpretation of causation means that if A causes B, then A must always be followed by B. In this sense, smoking does not cause cancer because some smokers never develop cancer. On the other hand, a probabilistic interpretation simply means that causes raise the probability of their effects. In this sense, changes in meteorological readings associated with a storm do cause that storm, since they raise its probability. (However, simply looking at a barometer does not change the probability of the storm, for a more detailed analysis, see:). == Examples == In a simple view, releasing one's hand from a hammer causes the hammer to fall. However, doing so in outer space does not produce the same outcome, calling into question if releasing one's fingers from a hammer always causes it to fall. A causal graph could be created to acknowledge that both the presence of gravity and the release of the hammer contribute to its falling. However, it would be very surprising if the surface underneath the hammer affected its falling. This essentially states the Causal Markov Condition, that given the existence of gravity the release of the hammer, it will fall regardless of what is beneath it. == Implications == === Dependence and Causation === It follows from the definition that if X and Y are in V and are probabilistically dependent, then either X causes Y, Y causes X, or X and Y are both effects of some common cause Z in V. This definition was seminally introduced by Hans Reichenbach as the Common Cause Principle (CCP). === Screening === It once again follows from the definition that the parents of X screen X from other "indirect causes" of X (parents of Parents(X)) and other effects of Parents(X) which are not also effects of X.
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