A number of different Markov models of DNA sequence evolution have been proposed. These substitution models differ in terms of the parameters used to describe the rates at which one nucleotide replaces another during evolution. These models are frequently used in molecular phylogenetic analyses. In particular, they are used during the calculation of likelihood of a tree (in Bayesian and maximum likelihood approaches to tree estimation) and they are used to estimate the evolutionary distance between sequences from the observed differences between the sequences. == Introduction == These models are phenomenological descriptions of the evolution of DNA as a string of four discrete states. These Markov models do not explicitly depict the mechanism of mutation nor the action of natural selection. Rather they describe the relative rates of different changes. For example, mutational biases and purifying selection favoring conservative changes are probably both responsible for the relatively high rate of transitions compared to transversions in evolving sequences. However, the Kimura (K80) model described below only attempts to capture the effect of both forces in a parameter that reflects the relative rate of transitions to transversions. Evolutionary analyses of sequences are conducted on a wide variety of time scales. Thus, it is convenient to express these models in terms of the instantaneous rates of change between different states (the Q matrices below). If we are given a starting (ancestral) state at one position, the model's Q matrix and a branch length expressing the expected number of changes to have occurred since the ancestor, then we can derive the probability of the descendant sequence having each of the four states. The mathematical details of this transformation from rate-matrix to probability matrix are described in the mathematics of substitution models section of the substitution model page. By expressing models in terms of the instantaneous rates of change we can avoid estimating a large numbers of parameters for each branch on a phylogenetic tree (or each comparison if the analysis involves many pairwise sequence comparisons). The models described on this page describe the evolution of a single site within a set of sequences. They are often used for analyzing the evolution of an entire locus by making the simplifying assumption that different sites evolve independently and are identically distributed. This assumption may be justifiable if the sites can be assumed to be evolving neutrally. If the primary effect of natural selection on the evolution of the sequences is to constrain some sites, then models of among-site rate-heterogeneity can be used. This approach allows one to estimate only one matrix of relative rates of substitution, and another set of parameters describing the variance in the total rate of substitution across sites. == DNA evolution as a continuous-time Markov chain == === Continuous-time Markov chains === Continuous-time Markov chains have the usual transition matrices which are, in addition, parameterized by time, t {\displaystyle t} . Specifically, if E 1 , E 2 , E 3 , E 4 {\displaystyle E_{1},E_{2},E_{3},E_{4}} are the states, then the transition matrix P ( t ) = ( P i j ( t ) ) {\displaystyle P(t)={\big (}P_{ij}(t){\big )}} where each individual entry, P i j ( t ) {\displaystyle P_{ij}(t)} refers to the probability that state E i {\displaystyle E_{i}} will change to state E j {\displaystyle E_{j}} in time t {\displaystyle t} . Example: We would like to model the substitution process in DNA sequences (i.e. Jukes–Cantor, Kimura, etc.) in a continuous-time fashion. The corresponding transition matrices will look like: P ( t ) = ( p A A ( t ) p A G ( t ) p A C ( t ) p A T ( t ) p G A ( t ) p G G ( t ) p G C ( t ) p G T ( t ) p C A ( t ) p C G ( t ) p C C ( t ) p C T ( t ) p T A ( t ) p T G ( t ) p T C ( t ) p T T ( t ) ) {\displaystyle P(t)={\begin{pmatrix}p_{\mathrm {AA} }(t)&p_{\mathrm {AG} }(t)&p_{\mathrm {AC} }(t)&p_{\mathrm {AT} }(t)\\p_{\mathrm {GA} }(t)&p_{\mathrm {GG} }(t)&p_{\mathrm {GC} }(t)&p_{\mathrm {GT} }(t)\\p_{\mathrm {CA} }(t)&p_{\mathrm {CG} }(t)&p_{\mathrm {CC} }(t)&p_{\mathrm {CT} }(t)\\p_{\mathrm {TA} }(t)&p_{\mathrm {TG} }(t)&p_{\mathrm {TC} }(t)&p_{\mathrm {TT} }(t)\end{pmatrix}}} where the top-left and bottom-right 2 × 2 blocks correspond to transition probabilities and the top-right and bottom-left 2 × 2 blocks corresponds to transversion probabilities. Assumption: If at some time t 0 {\displaystyle t_{0}} , the Markov chain is in state E i {\displaystyle E_{i}} , then the probability that at time t 0 + t {\displaystyle t_{0}+t} , it will be in state E j {\displaystyle E_{j}} depends only upon i {\displaystyle i} , j {\displaystyle j} and t {\displaystyle t} . This then allows us to write that probability as p i j ( t ) {\displaystyle p_{ij}(t)} . Theorem: Continuous-time transition matrices satisfy: P ( t + τ ) = P ( t ) P ( τ ) {\displaystyle P(t+\tau )=P(t)P(\tau )} Note: There is here a possible confusion between two meanings of the word transition. (i) In the context of Markov chains, transition is the general term for the change between two states. (ii) In the context of nucleotide changes in DNA sequences, transition is a specific term for the exchange between either the two purines (A ↔ G) or the two pyrimidines (C ↔ T) (for additional details, see the article about transitions in genetics). By contrast, an exchange between one purine and one pyrimidine is called a transversion. === Deriving the dynamics of substitution === Consider a DNA sequence of fixed length m evolving in time by base replacement. Assume that the processes followed by the m sites are Markovian independent, identically distributed and that the process is constant over time. For a particular site, let E = { A , G , C , T } {\displaystyle {\mathcal {E}}=\{A,\,G,\,C,\,T\}} be the set of possible states for the site, and p ( t ) = ( p A ( t ) , p G ( t ) , p C ( t ) , p T ( t ) ) {\displaystyle \mathbf {p} (t)=(p_{A}(t),\,p_{G}(t),\,p_{C}(t),\,p_{T}(t))} their respective probabilities at time t {\displaystyle t} . For two distinct x , y ∈ E {\displaystyle x,y\in {\mathcal {E}}} , let μ x y {\displaystyle \mu _{xy}\ } be the transition rate from state x {\displaystyle x} to state y {\displaystyle y} . Similarly, for any x {\displaystyle x} , let the total rate of change from x {\displaystyle x} be μ x = ∑ y ≠ x μ x y . {\displaystyle \mu _{x}=\sum _{y\neq x}\mu _{xy}\,.} The changes in the probability distribution p A ( t ) {\displaystyle p_{A}(t)} for small increments of time Δ t {\displaystyle \Delta t} are given by p A ( t + Δ t ) = p A ( t ) − p A ( t ) μ A Δ t + ∑ x ≠ A p x ( t ) μ x A Δ t . {\displaystyle p_{A}(t+\Delta t)=p_{A}(t)-p_{A}(t)\mu _{A}\Delta t+\sum _{x\neq A}p_{x}(t)\mu _{xA}\Delta t\,.} In other words, (in frequentist language), the frequency of A {\displaystyle A} 's at time t + Δ t {\displaystyle t+\Delta t} is equal to the frequency at time t {\displaystyle t} minus the frequency of the lost A {\displaystyle A} 's plus the frequency of the newly created A {\displaystyle A} 's. Similarly for the probabilities p G ( t ) {\displaystyle p_{G}(t)} , p C ( t ) {\displaystyle p_{C}(t)} and p T ( t ) {\displaystyle p_{T}(t)} . These equations can be written compactly as p ( t + Δ t ) = p ( t ) + p ( t ) Q Δ t , {\displaystyle \mathbf {p} (t+\Delta t)=\mathbf {p} (t)+\mathbf {p} (t)Q\Delta t\,,} where Q = ( − μ A μ A G μ A C μ A T μ G A − μ G μ G C μ G T μ C A μ C G − μ C μ C T μ T A μ T G μ T C − μ T ) {\displaystyle Q={\begin{pmatrix}-\mu _{A}&\mu _{AG}&\mu _{AC}&\mu _{AT}\\\mu _{GA}&-\mu _{G}&\mu _{GC}&\mu _{GT}\\\mu _{CA}&\mu _{CG}&-\mu _{C}&\mu _{CT}\\\mu _{TA}&\mu _{TG}&\mu _{TC}&-\mu _{T}\end{pmatrix}}} is known as the rate matrix. Note that, by definition, the sum of the entries in each row of Q {\displaystyle Q} is equal to zero. It follows that p ′ ( t ) = p ( t ) Q . {\displaystyle \mathbf {p} '(t)=\mathbf {p} (t)Q\,.} For a stationary process, where Q {\displaystyle Q} does not depend on time t, this differential equation can be solved. First, P ( t ) = exp ( t Q ) , {\displaystyle P(t)=\exp(tQ),} where exp ( t Q ) {\displaystyle \exp(tQ)} denotes the exponential of the matrix t Q {\displaystyle tQ} . As a result, p ( t ) = p ( 0 ) P ( t ) = p ( 0 ) exp ( t Q ) . {\displaystyle \mathbf {p} (t)=\mathbf {p} (0)P(t)=\mathbf {p} (0)\exp(tQ)\,.} === Ergodicity === If the Markov chain is irreducible, i.e. if it is always possible to go from a state x {\displaystyle x} to a state y {\displaystyle y} (possibly in several steps), then it is also ergodic. As a result, it has a unique stationary distribution π = { π x , x ∈ E } {\displaystyle {\boldsymbol {\pi }}=\{\pi _{x},\,x\in {\mathcal {E}}\}} , where π x {\displaystyle \pi _{x}} corresponds to the proportion of time spent in state x {\displaystyle x} after the Markov chain has run for an infinite amount of time. In DNA evo
Hard sigmoid
In artificial intelligence, especially computer vision and artificial neural networks, a hard sigmoid is non-smooth function used in place of a sigmoid function. These retain the basic shape of a sigmoid, rising from 0 to 1, but using simpler functions, especially piecewise linear functions or piecewise constant functions. These are preferred where speed of computation is more important than precision. == Examples == The most extreme examples are the sign function or Heaviside step function, which go from −1 to 1 or 0 to 1 (which to use depends on normalization) at 0. Other examples include the Theano library, which provides two approximations: ultra_fast_sigmoid, which is a multi-part piecewise approximation and hard_sigmoid, which is a 3-part piecewise linear approximation (output 0, line with slope 0.2, output 1).
Resilience (mathematics)
In mathematical modeling, resilience refers to the ability of a dynamical system to recover from perturbations and return to its original stable steady state. It is a measure of the stability and robustness of a system in the face of changes or disturbances. If a system is not resilient enough, it is more susceptible to perturbations and can more easily undergo a critical transition. A common analogy used to explain the concept of resilience of an equilibrium is one of a ball in a valley. A resilient steady state corresponds to a ball in a deep valley, so any push or perturbation will very quickly lead the ball to return to the resting point where it started. On the other hand, a less resilient steady state corresponds to a ball in a shallow valley, so the ball will take a much longer time to return to the equilibrium after a perturbation. The concept of resilience is particularly useful in systems that exhibit tipping points, whose study has a long history that can be traced back to catastrophe theory. While this theory was initially overhyped and fell out of favor, its mathematical foundation remains strong and is now recognized as relevant to many different systems. == History == In 1973, Canadian ecologist C. S. Holling proposed a definition of resilience in the context of ecological systems. According to Holling, resilience is "a measure of the persistence of systems and of their ability to absorb change and disturbance and still maintain the same relationships between populations or state variables". Holling distinguished two types of resilience: engineering resilience and ecological resilience. Engineering resilience refers to the ability of a system to return to its original state after a disturbance, such as a bridge that can be repaired after an earthquake. Ecological resilience, on the other hand, refers to the ability of a system to maintain its identity and function despite a disturbance, such as a forest that can regenerate after a wildfire while maintaining its biodiversity and ecosystem services. With time, the once well-defined and unambiguous concept of resilience has experienced a gradual erosion of its clarity, becoming more vague and closer to an umbrella term than a specific concrete measure. == Definition == Mathematically, resilience can be approximated by the inverse of the return time to an equilibrium given by resilience ≡ − Re ( λ 1 ( A ) ) {\displaystyle {\text{resilience}}\equiv -{\text{Re}}(\lambda _{1}({\textbf {A}}))} where λ 1 {\textstyle \lambda _{1}} is the maximum eigenvalue of matrix A {\textstyle {\textbf {A}}} . The largest this value is, the faster a system returns to the original stable steady state, or in other words, the faster the perturbations decay. == Applications and examples == In ecology, resilience might refer to the ability of the ecosystem to recover from disturbances such as fires, droughts, or the introduction of invasive species. A resilient ecosystem would be one that is able to adapt to these changes and continue functioning, while a less resilient ecosystem might experience irreversible damage or collapse. The exact definition of resilience has remained vague for practical matters, which has led to a slow and proper application of its insights for management of ecosystems. In epidemiology, resilience may refer to the ability of a healthy community to recover from the introduction of infected individuals. That is, a resilient system is more likely to remain at the disease-free equilibrium after the invasion of a new infection. Some stable systems exhibit critical slowing down where, as they approach a basic reproduction number of 1, their resilience decreases, hence taking a longer time to return to the disease-free steady state. Resilience is an important concept in the study of complex systems, where there are many interacting components that can affect each other in unpredictable ways. Mathematical models can be used to explore the resilience of such systems and to identify strategies for improving their resilience in the face of environmental or other changes. For example, when modelling networks it is often important to be able to quantify network resilience, or network robustness, to the loss of nodes. Scale-free networks are particularly resilient since most of their nodes have few links. This means that if some nodes are randomly removed, it is more likely that the nodes with fewer connections are taken out, thus preserving the key properties of the network.
ComfyUI
ComfyUI is an open source, node-based program that allows users to generate images from a series of text prompts. It uses free diffusion models such as Stable Diffusion as the base model for its image capabilities combined with other tools such as ControlNet and LCM Low-rank adaptation with each tool being represented by a node in the program. == History == ComfyUI was released on GitHub in January 2023. According to comfyanonymous, the creator, a major goal of the project was to improve on existing software designs in terms of the user interface. The creator had been involved with Stability AI but by 3 June 2024 that involvement had ended and an organization called Comfy Org had been created along with the core developers. In July 2024, Nvidia announced support for ComfyUI within its RTX Remix modding software. In August 2024, support was added for the Flux diffusion model developed by Black Forest Labs, and Comfy Org joined the Open Model Initiative created by the Linux Foundation. As of Sept 2025, the project has 89.2k stars on GitHub. ComfyUI is one of the most popular user interfaces for Stable Diffusion, along with Automatic1111. == Features == ComfyUI's main feature is that it is node based. Each node has a function such as "load a model" or "write a prompt". The nodes are connected to form a control-flow graph called a workflow. When a prompt is queued, a highlighted frame appears around the currently executing node, starting from "load checkpoint" and ending with the final image and its save location. Workflows commonly consist of tens of nodes, forming a complex directed acyclic graph. Node types include loading a model, specifying prompts, samplers, schedulers, VAE decoders, face restoration and upscaling models, LoRAs, embeddings, and ControlNets. Several samplers are supported, such as Euler, Euler_a, dpmpp_2m_sde and dpmpp_3m_sde. Workflows can be saved to a file, allowing users to re-use node workflows and share them with other users. The file format for the workflows is in JSON and can be embedded in the generated images. Users have also created custom extensions to the base system which are exposed as new nodes, such as the extension for AnimateDiff, which aims to create videos. ComfyUI has been described as more complex compared to other diffusion UIs such as Automatic1111. A default node group is also included with the program. As of December 2024, 1,674 nodes were supported. ComfyUI Supports multiple text-to-image models including, Stable Diffusion, Flux and Tencent's Hunyuan-DiT, as well as custom models from Civitai like Pony. == LLMVision extension compromise == In June 2024, a hacker group called "Nullbulge" compromised an extension of ComfyUI to add malicious code to it. The compromised extension, called ComfyUI_LLMVISION, was used for integrating the interface with AI language models GPT-4 and Claude 3, and was hosted on GitHub. Nullbulge hosted a list of hundreds of ComfyUI users' login details across multiple services on its website, while users of the extension reported receiving numerous login notifications. vpnMentor conducted security research on the extension and claimed it could "steal crypto wallets, screenshot the user’s screen, expose device information and IP addresses, and steal files that contain certain keywords or extensions". Nullbulge's website claims they targeted users who committed "one of our sins", which included AI-art generation, art theft, promoting cryptocurrency, and any other kind of theft from artists such as from Patreon. They claimed that they were "a collective of individuals who believe in the importance of protecting artists' rights and ensuring fair compensation for their work" and that they believed that "AI-generated artwork is detrimental to the creative industry and should be discouraged".
Computer Power and Human Reason
Computer Power and Human Reason: From Judgment to Calculation is a 1976 nonfiction book by German-American computer scientist Joseph Weizenbaum in which he contends that while artificial intelligence may be possible, we should never allow computers to make important decisions, as they will always lack human qualities such as compassion and wisdom. == Background == Before writing Computer Power and Human Reason, Weizenbaum had garnered significant attention for creating the ELIZA program, an early milestone in conversational computing. His firsthand observation of people attributing human-like qualities to a simple program prompted him to reflect more deeply on society's readiness to entrust moral and ethical considerations to machines. == Reception and legacy == Computer Power and Human Reason sparked scholarly debate on the acceptable scope of AI applications, particularly in fields where human welfare and ethical considerations are paramount. Early academic reviews highlighted that Weizenbaum's stance pushed readers to recognize that even as computers grow more capable, they lack the intrinsic moral compass and empathy required for certain kinds of judgment. The book caused disagreement with, and separation from, other members of the artificial intelligence research community, a status the author later said he'd come to take pride in.
Zardoz (computer security)
In computer security, the Security-Digest list, better known as the Zardoz list, was a semi-private full disclosure mailing list run by Neil Gorsuch from 1989 through 1991. It identified weaknesses in systems and gave directions on where to find them. It was a perennial target for computer hackers, who sought archives of the list for information on undisclosed software vulnerabilities. == Membership restrictions == Access to Zardoz was approved on a case-by-case basis by Gorsuch, principally by reference to the user account used to send subscription requests; requests were approved for root users, valid UUCP owners, or system administrators listed at the NIC. The openness of the list to users other than Unix system administrators was a regular topic of conversation, with participants expressing concern that vulnerabilities and exploitation details disclosed on the list were liable to spread to hackers. The circulation of Zardoz postings was an open secret among computer hackers, and mocked in a Phrack parody of an IRC channel populated by security experts. == Notable participants == Keith Bostic discussed BSD Sendmail vulnerabilities Chip Salzenberg discussed Peter Honeyman's posting of a UUCP worm, and shell script security Gene Spafford discussed VMS and Ultrix bugs, and relayed law enforcement enquiries about the Morris Worm Tom Christiansen discussed SUID shell scripts Chris Torek discussed devising exploits from general descriptions of vulnerabilities Henry Spencer discussed Unix security Brendan Kehoe discussed systems security Alec Muffett announced Crack, the Unix password cracker The majority of Zardoz participants were Unix systems administrators and C software developers. Neil Gorsuch and Gene Spafford were the most prolific contributors to the list.
AlphaGo
AlphaGo is a computer program that plays the board game Go. It was developed by the London-based DeepMind Technologies, an acquired subsidiary of Google. Subsequent versions of AlphaGo became increasingly powerful, including a version that competed under the name Master. After retiring from competitive play, AlphaGo Master was succeeded by an even more powerful version known as AlphaGo Zero, which was completely self-taught without learning from human games. AlphaGo Zero was then generalized into a program known as AlphaZero, which played additional games, including chess and shogi. AlphaZero has in turn been succeeded by a program known as MuZero which learns without being taught the rules. AlphaGo and its successors use a Monte Carlo tree search algorithm to find its moves based on knowledge previously acquired by machine learning, specifically by an artificial neural network (a deep learning method) by extensive training, both from human and computer play. A neural network is trained to identify the best moves and the winning percentages of these moves. This neural network improves the strength of the tree search, resulting in stronger move selection in the next iteration. In October 2015, in a match against Fan Hui, the original AlphaGo became the first computer Go program to beat a human professional Go player without handicap on a full-sized 19×19 board. In March 2016, it beat Lee Sedol in a five-game match, the first time a computer Go program has beaten a 9-dan professional without handicap. Although it lost to Lee Sedol in the fourth game, Lee resigned in the final game, giving a final score of 4 games to 1 in favour of AlphaGo. In recognition of the victory, AlphaGo was awarded an honorary 9-dan by the Korea Baduk Association. The lead up and the challenge match with Lee Sedol were documented in a documentary film also titled AlphaGo, directed by Greg Kohs. The win by AlphaGo was chosen by Science as one of the Breakthrough of the Year runners-up on 22 December 2016. At the 2017 Future of Go Summit, the Master version of AlphaGo beat Ke Jie, the number one ranked player in the world at the time, in a three-game match, after which AlphaGo was awarded professional 9-dan by the Chinese Weiqi Association. After the match between AlphaGo and Ke Jie, DeepMind retired AlphaGo, while continuing AI research in other areas. The self-taught AlphaGo Zero achieved a 100–0 victory against the early competitive version of AlphaGo, and its successor AlphaZero was perceived as the world's top player in Go by the end of the 2010s. == History == Go is considered much more difficult for computers to win than other games such as chess, because its strategic and aesthetic nature makes it hard to directly construct an evaluation function, and its much larger branching factor makes it prohibitively difficult to use traditional AI methods such as alpha–beta pruning, tree traversal and heuristic search. Almost two decades after IBM's computer Deep Blue beat world chess champion Garry Kasparov in the 1997 match, the strongest Go programs using artificial intelligence techniques only reached about amateur 5-dan level, and still could not beat a professional Go player without a handicap. In 2012, the software program Zen, running on a four PC cluster, beat Masaki Takemiya (9p) twice at five- and four-stone handicaps. In 2013, Crazy Stone beat Yoshio Ishida (9p) at a four-stone handicap. According to DeepMind's David Silver, the AlphaGo research project was formed around 2014 to test how well a neural network using deep learning can compete at Go. AlphaGo represents a significant improvement over previous Go programs. In 500 games against other available Go programs, including Crazy Stone and Zen, AlphaGo running on a single computer won all but one. In a similar matchup, AlphaGo running on multiple computers won all 500 games played against other Go programs, and 77% of games played against AlphaGo running on a single computer. The distributed version in October 2015 was using 1,202 CPUs and 176 GPUs. === Match against Fan Hui === In October 2015, the distributed version of AlphaGo defeated the European Go champion Fan Hui, a 2-dan (out of 9 dan possible) professional, five to zero. This was the first time a computer Go program had beaten a professional human player on a full-sized board without handicap. The announcement of the news was delayed until 27 January 2016 to coincide with the publication of a paper in the journal Nature describing the algorithms used. === Match against Lee Sedol === AlphaGo played South Korean professional Go player Lee Sedol, ranked 9-dan, one of the best players at Go, with five games taking place at the Four Seasons Hotel in Seoul, South Korea on 9, 10, 12, 13, and 15 March 2016, which were video-streamed live. Out of five games, AlphaGo won four games and Lee won the fourth game which made him recorded as the only human player who beat AlphaGo in all of its 74 official games. AlphaGo ran on Google's cloud computing with its servers located in the United States. The match used Chinese rules with a 7.5-point komi, and each side had two hours of thinking time plus three 60-second byoyomi periods. The version of AlphaGo playing against Lee used a similar amount of computing power as was used in the Fan Hui match. The Economist reported that it used 1,920 CPUs and 280 GPUs. At the time of play, Lee Sedol had the second-highest number of Go international championship victories in the world after South Korean player Lee Chang-ho who kept the world championship title for 16 years. Since there is no single official method of ranking in international Go, the rankings may vary among the sources. While he was ranked top sometimes, some sources ranked Lee Sedol as the fourth-best player in the world at the time. AlphaGo was not specifically trained to face Lee nor was designed to compete with any specific human players. The first three games were won by AlphaGo following resignations by Lee. However, Lee beat AlphaGo in the fourth game, winning by resignation at move 180. AlphaGo then continued to achieve a fourth win, winning the fifth game by resignation. The prize was US$1 million. Since AlphaGo won four out of five and thus the series, the prize will be donated to charities, including UNICEF. Lee Sedol received $150,000 for participating in all five games and an additional $20,000 for his win in Game 4. In June 2016, at a presentation held at a university in the Netherlands, Aja Huang, one of the Deep Mind team, revealed that they had patched the logical weakness that occurred during the 4th game of the match between AlphaGo and Lee, and that after move 78 (which was dubbed the "divine move" by many professionals), it would play as intended and maintain Black's advantage. Before move 78, AlphaGo was leading throughout the game, but Lee's move caused the program's computing powers to be diverted and confused. Huang explained that AlphaGo's policy network of finding the most accurate move order and continuation did not precisely guide AlphaGo to make the correct continuation after move 78, since its value network did not determine Lee's 78th move as being the most likely, and therefore when the move was made AlphaGo could not make the right adjustment to the logical continuation. === Sixty online games === On 29 December 2016, a new account on the Tygem server named "Magister" (shown as 'Magist' at the server's Chinese version) from South Korea began to play games with professional players. It changed its account name to "Master" on 30 December, then moved to the FoxGo server on 1 January 2017. On 4 January, DeepMind confirmed that the "Magister" and the "Master" were both played by an updated version of AlphaGo, called AlphaGo Master. As of 5 January 2017, AlphaGo Master's online record was 60 wins and 0 losses, including three victories over Go's top-ranked player, Ke Jie, who had been quietly briefed in advance that Master was a version of AlphaGo. After losing to Master, Gu Li offered a bounty of 100,000 yuan (US$14,400) to the first human player who could defeat Master. Master played at the pace of 10 games per day. Many quickly suspected it to be an AI player due to little or no resting between games. Its adversaries included many world champions such as Ke Jie, Park Jeong-hwan, Yuta Iyama, Tuo Jiaxi, Mi Yuting, Shi Yue, Chen Yaoye, Li Qincheng, Gu Li, Chang Hao, Tang Weixing, Fan Tingyu, Zhou Ruiyang, Jiang Weijie, Chou Chun-hsun, Kim Ji-seok, Kang Dong-yun, Park Yeong-hun, and Won Seong-jin; national champions or world championship runners-up such as Lian Xiao, Tan Xiao, Meng Tailing, Dang Yifei, Huang Yunsong, Yang Dingxin, Gu Zihao, Shin Jinseo, Cho Han-seung, and An Sungjoon. All 60 games except one were fast-paced games with three 20 or 30 seconds byo-yomi. Master offered to extend the byo-yomi to one minute when playing with Nie Weiping in consideration of his age. After winning its 59th game Master revealed itse