Margaret (Maghi) Daniel King is a retired British computational linguist known for her work on evaluating the quality of machine translation. She is an honorary professor in the Department of Translation Technology of the University of Geneva in Switzerland, and the former director of the Dalle Molle Institute for Semantic and Cognitive Studies at the University of Geneva. == Education and career == King read classics, Ancient History and Philosophy (Greats) at the University of Oxford, worked as a computer programmer, and became a lecturer in the Department of Computation at the University of Manchester Institute of Science and Technology. She moved to the Dalle Molle Institute for Semantic and Cognitive Studies (ISSCO) in 1974. In 1976, ISSCO became part of the University of Geneva, and she continued there, becoming ISSCO's director in 1978. She remained director until her retirement in 2006. == Recognition == King is a Fellow of the European Association for Artificial Intelligence (formerly ECCAI), elected in 1999.
Deep Learning Indaba
The Deep Learning Indaba is an annual conference and educational event that aims to strengthen machine learning and artificial intelligence (AI) capacity across Africa. Launched in 2017, it brings together students, researchers, industry practitioners, and policymakers from across the African continent. == History == The Deep Learning Indaba began in 2017 at the University of the Witwatersrand with over 300 participants from 23 African countries, offering tutorials in advanced AI topics and featuring notable speakers like Nando de Freitas. In 2018, it expanded to 650 delegates at Stellenbosch University, introducing parallel sessions to encourage collaboration. The 2019 edition in Nairobi, Kenya, reflected further growth, with increasing sponsorship and support from major tech companies like Google and Microsoft. === Deep Learning IndabaX ===
Nortel Speech Server
The Nortel Speech Server (formerly known as Periphonics Speech Processing Platform) in telecommunications is a speech processing system that was originally developed by Nortel. Following the bankruptcy of Nortel, it is now sold by Avaya. The system is primarily used for large vocabulary speech recognition, natural language understanding, text-to-speech, and speaker verification. The Nortel Speech Server was based on the Periphonics OSCAR platform. The original OSCAR Platform was based upon Solaris servers. The current range of Speech Servers is Windows based. Nortel Speech Server is a component of the MPS 500, MPS 1000, and ICP platforms. On MPS systems, it may be used to stream prerecorded audio.
AlphaZero
AlphaZero is a computer program developed by artificial intelligence research company DeepMind to master the games of chess, shogi and go. This algorithm uses an approach similar to AlphaGo Zero. On December 5, 2017, the DeepMind team released a preprint paper introducing AlphaZero, which would soon play three games by defeating world-champion chess engines Stockfish, Elmo, and the three-day version of AlphaGo Zero. In each case it made use of custom tensor processing units (TPUs) that the Google programs were optimized to use. AlphaZero was trained solely via self-play using 5,000 first-generation TPUs to generate the games and 64 second-generation TPUs to train the neural networks, all in parallel, with no access to opening books or endgame tables. After four hours of training, DeepMind estimated AlphaZero was playing chess at a higher Elo rating than Stockfish 8; after nine hours of training, the algorithm defeated Stockfish 8 in a time-controlled 100-game tournament (28 wins, 0 losses, and 72 draws). The trained algorithm played on a single machine with four TPUs. DeepMind's paper on AlphaZero was published in the journal Science on 7 December 2018. While the actual AlphaZero program has not been released to the public, the algorithm described in the paper has been implemented in publicly available software. In 2019, DeepMind published a new paper detailing MuZero, a new algorithm able to generalize AlphaZero's work, playing both Atari and board games without knowledge of the rules or representations of the game. == Relation to AlphaGo Zero == AlphaZero (AZ) is a more generalized variant of the AlphaGo Zero (AGZ) algorithm, and is able to play shogi and chess as well as Go. Differences between AZ and AGZ include: AZ has hard-coded rules for setting search hyperparameters. The neural network is now updated continually. AZ doesn't use symmetries, unlike AGZ. Chess or Shogi can end in a draw unlike Go; therefore, AlphaZero takes into account the possibility of a drawn game. == Stockfish and Elmo == Comparing Monte Carlo tree search searches, AlphaZero searches just 80,000 positions per second in chess and 40,000 in shogi, compared to 70 million for Stockfish and 35 million for Elmo. AlphaZero compensates for the lower number of evaluations by using its deep neural network to focus much more selectively on the most promising variation. == Training == AlphaZero was trained by simply playing against itself multiple times, using 5,000 first-generation TPUs to generate the games and 64 second-generation TPUs to train the neural networks. In parallel, the in-training AlphaZero was periodically matched against its benchmark (Stockfish, Elmo, or AlphaGo Zero) in brief one-second-per-move games to determine how well the training was progressing. DeepMind judged that AlphaZero's performance exceeded the benchmark after around four hours of training for Stockfish, two hours for Elmo, and eight hours for AlphaGo Zero. == Preliminary results == === Outcome === ==== Chess ==== In AlphaZero's chess match against Stockfish 8 (2016 TCEC world champion), each program was given one minute per move. AlphaZero was flying the English flag, while Stockfish the Norwegian. Stockfish was allocated 64 threads and a hash size of 1 GB, a setting that Stockfish's Tord Romstad later criticized as suboptimal. AlphaZero was trained on chess for a total of nine hours before the match. During the match, AlphaZero ran on a single machine with four application-specific TPUs. In 100 games from the normal starting position, AlphaZero won 25 games as White, won 3 as Black, and drew the remaining 72. In a series of twelve, 100-game matches (of unspecified time or resource constraints) against Stockfish starting from the 12 most popular human openings, AlphaZero won 290, drew 886 and lost 24. ==== Shogi ==== AlphaZero was trained on shogi for a total of two hours before the tournament. In 100 shogi games against Elmo (World Computer Shogi Championship 27 summer 2017 tournament version with YaneuraOu 4.73 search), AlphaZero won 90 times, lost 8 times and drew twice. As in the chess games, each program got one minute per move, and Elmo was given 64 threads and a hash size of 1 GB. ==== Go ==== After 34 hours of self-learning of Go and against AlphaGo Zero, AlphaZero won 60 games and lost 40. === Analysis === DeepMind stated in its preprint, "The game of chess represented the pinnacle of AI research over several decades. State-of-the-art programs are based on powerful engines that search many millions of positions, leveraging handcrafted domain expertise and sophisticated domain adaptations. AlphaZero is a generic reinforcement learning algorithm – originally devised for the game of go – that achieved superior results within a few hours, searching a thousand times fewer positions, given no domain knowledge except the rules." DeepMind's Demis Hassabis, a chess player himself, called AlphaZero's play style "alien": It sometimes wins by offering counterintuitive sacrifices, like offering up a queen and bishop to exploit a positional advantage. "It's like chess from another dimension." Given the difficulty in chess of forcing a win against a strong opponent, the +28 –0 =72 result is a significant margin of victory. However, some grandmasters, such as Hikaru Nakamura and Komodo developer Larry Kaufman, downplayed AlphaZero's victory, arguing that the match would have been closer if the programs had access to an opening database (since Stockfish was optimized for that scenario). Romstad additionally pointed out that Stockfish is not optimized for rigidly fixed-time moves and the version used was a year old. Similarly, some shogi observers argued that the Elmo hash size was too low, that the resignation settings and the "EnteringKingRule" settings (cf. shogi § Entering King) may have been inappropriate, and that Elmo is already obsolete compared with newer programs. === Reaction and criticism === Papers headlined that the chess training took only four hours: "It was managed in little more than the time between breakfast and lunch." Wired described AlphaZero as "the first multi-skilled AI board-game champ". AI expert Joanna Bryson noted that Google's "knack for good publicity" was putting it in a strong position against challengers. "It's not only about hiring the best programmers. It's also very political, as it helps make Google as strong as possible when negotiating with governments and regulators looking at the AI sector." Human chess grandmasters generally expressed excitement about AlphaZero. Danish grandmaster Peter Heine Nielsen likened AlphaZero's play to that of a superior alien species. Norwegian grandmaster Jon Ludvig Hammer characterized AlphaZero's play as "insane attacking chess" with profound positional understanding. Former champion Garry Kasparov said, "It's a remarkable achievement, even if we should have expected it after AlphaGo." Grandmaster Hikaru Nakamura was less impressed, stating: "I don't necessarily put a lot of credibility in the results simply because my understanding is that AlphaZero is basically using the Google supercomputer and Stockfish doesn't run on that hardware; Stockfish was basically running on what would be my laptop. If you wanna have a match that's comparable you have to have Stockfish running on a supercomputer as well." Top US correspondence chess player Wolff Morrow was also unimpressed, claiming that AlphaZero would probably not make the semifinals of a fair competition such as TCEC where all engines play on equal hardware. Morrow further stated that although he might not be able to beat AlphaZero if AlphaZero played drawish openings such as the Petroff Defence, AlphaZero would not be able to beat him in a correspondence chess game either. Motohiro Isozaki, the author of YaneuraOu, noted that although AlphaZero did comprehensively beat Elmo, the rating of AlphaZero in shogi stopped growing at a point which is at most 100–200 higher than Elmo. This gap is not that high, and Elmo and other shogi software should be able to catch up in 1–2 years. == Final results == DeepMind addressed many of the criticisms in their final version of the paper, published in December 2018 in Science. They further clarified that AlphaZero was not running on a supercomputer; it was trained using 5,000 tensor processing units (TPUs), but only ran on four TPUs and a 44-core CPU in its matches. === Chess === In the final results, Stockfish 9 dev ran under the same conditions as in the TCEC superfinal: 44 CPU cores, Syzygy endgame tablebases, and a 32 GB hash size. Instead of a fixed time control of one move per minute, both engines were given 3 hours plus 15 seconds per move to finish the game. AlphaZero ran on a much more powerful machine with four TPUs in addition to 44 CPU cores. In a 1000-game match, AlphaZero won with a score of 155 wins, 6 losses, and 839 draws. DeepMind also played a series of games using the TCEC opening positions; AlphaZero also won
Demis Hassabis
Sir Demis Hassabis (/ˈdɛ.mɪs/ DE-mis /hɑːˈsɑː.bis/ hah-SAH-bees; born Dimitrios Hassapis, Greek: Δημήτριος Χασάπης, 27 July 1976) is a British artificial intelligence (AI) researcher and entrepreneur. He is the chief executive officer and co-founder of Google DeepMind and Isomorphic Labs, and a UK Government AI Adviser. In 2024, Hassabis and John M. Jumper were jointly awarded the Nobel Prize in Chemistry for their AI research contributions to protein structure prediction. Hassabis is a Fellow of the Royal Society and has won awards for his research efforts, including the Breakthrough Prize, the Canada Gairdner International Award and the Lasker Award. He was appointed a CBE in 2017, and knighted in 2024 for his work on AI. He was also listed among the Time 100 most influential people in the world in 2017 and 2025, and was one of the "Architects of AI" collectively chosen as Time's 2025 Person of the Year. == Early life and education == Hassabis was born to Costas and Angela Hassapis. His father is a Greek Cypriot and his mother is a Chinese Singaporean. Demis grew up in North London. His original surname was "Hassapis" (Greek: Χασάπης), meaning "butcher" in Greek, but he later, according to Ingo Althöfer, "executed a point mutation by changing ‘p’ to ‘b’". One of his younger brothers still carries the original surname. In his early career, he was a video game AI programmer and designer, and an expert board games player. A child prodigy in chess from the age of four, when he first learnt chess by watching his father playing against his uncle, Hassabis reached master standard at the age of 13 with an Elo rating of 2300 and captained many of the England junior chess teams. He represented the University of Cambridge in the Oxford–Cambridge varsity chess matches of 1995, 1996 and 1997, winning a half blue. He first got interested in technology after buying his first computer in 1984, a ZX Spectrum 48K, funded from chess winnings. He taught himself how to program from books. He subsequently wrote his first AI program on a Commodore Amiga to play the reversi board game. Between 1988 and 1990, Hassabis was educated at Queen Elizabeth's School, Barnet, a boys' grammar school in North London. He was subsequently home-schooled by his parents for a year, before studying at the comprehensive school of Christ's College in East Finchley. He completed his A-level exams two years early at 16. === Bullfrog Productions === Asked by Cambridge University to take a gap year owing to his young age, Hassabis began his computer games career at Bullfrog Productions after entering an Amiga Power "Win-a-job-at-Bullfrog" competition. He began by playtesting on Syndicate and then at 17 co-designing and lead-programming on the 1994 game Theme Park, with the game's designer Peter Molyneux. Theme Park, a simulation video game, sold several million copies and inspired a whole genre of simulation sandbox games. Despite being offered a seven-figure sum to remain in the games industry, he turned it down. He earned enough from his gap year to pay his own way through university. === University of Cambridge === Hassabis left Bullfrog to study at Queens' College of the University of Cambridge, where he completed the Computer Science Tripos and graduated in 1997 with a double first. == Career and research == === Lionhead === After graduating from Cambridge, Hassabis worked at Lionhead Studios. Games designer Peter Molyneux, with whom Hassabis had worked at Bullfrog Productions, had recently founded the company. At Lionhead, Hassabis worked as lead AI programmer on the 2001 god game Black & White. === Elixir Studios === Hassabis left Lionhead in 1998 to found Elixir Studios, a London-based independent games developer, signing publishing deals with Eidos Interactive, Vivendi Universal and Microsoft. In addition to managing the company, Hassabis served as executive designer of the games Republic: The Revolution and Evil Genius. Each received BAFTA nominations for their interactive music scores, created by James Hannigan. The release of Elixir's first game, Republic: The Revolution, a highly ambitious and unusual political simulation game, was delayed due to its huge scope, which involved an AI simulation of the workings of an entire fictional country. The final game was reduced from its original vision and greeted with lukewarm reviews, receiving a Metacritic score of 62/100. Evil Genius, a tongue-in-cheek Austin Powers parody, fared much better with a score of 75/100. In April 2005 the intellectual property and technology rights were sold to various publishers and the studio was closed. === Neuroscience research === Following Elixir Studios, Hassabis returned to academia to obtain his PhD in cognitive neuroscience from UCL Queen Square Institute of Neurology in 2009 supervised by Eleanor Maguire. He sought to find inspiration in the human brain for new AI algorithms. He continued his neuroscience and artificial intelligence research as a visiting scientist jointly at Massachusetts Institute of Technology (MIT), in the lab of Tomaso Poggio, and Harvard University, before earning a Henry Wellcome postdoctoral research fellowship to the Gatsby Computational Neuroscience Unit at UCL in 2009 working with Peter Dayan. Working in the field of imagination, memory, and amnesia, he co-authored several influential papers published in Nature, Science, Neuron, and PNAS. His very first academic work, published in PNAS, was a landmark paper that showed systematically for the first time that patients with damage to their hippocampus, known to cause amnesia, were also unable to imagine themselves in new experiences. The finding established a link between the constructive process of imagination and the reconstructive process of episodic memory recall. Based on this work and a follow-up functional magnetic resonance imaging (fMRI) study, Hassabis developed a new theoretical account of the episodic memory system identifying scene construction, the generation and online maintenance of a complex and coherent scene, as a key process underlying both memory recall and imagination. This work received widespread coverage in the mainstream media and was listed in the top 10 scientific breakthroughs of the year by the journal Science. He later generalised these ideas to advance the notion of a 'simulation engine of the mind' whose role it was to imagine events and scenarios to aid with better planning. === DeepMind === Hassabis is the CEO and co-founder of DeepMind, a machine learning AI startup, founded in London in 2010 with Shane Legg and Mustafa Suleyman. Hassabis met Legg when both were postdocs at the Gatsby Computational Neuroscience Unit, and he and Suleyman had been friends through family. Hassabis also recruited his university friend and Elixir partner David Silver. DeepMind's mission is to "solve intelligence" and then use intelligence "to solve everything else". More concretely, DeepMind aims to combine insights from systems neuroscience with new developments in machine learning and computing hardware to unlock increasingly powerful general-purpose learning algorithms that will work towards the creation of an artificial general intelligence (AGI). The company has focused on training learning algorithms to master games, and in December 2013 it announced that it had made a pioneering breakthrough by training an algorithm called a Deep Q-Network (DQN) to play Atari games at a superhuman level by using only the raw pixels on the screen as inputs. DeepMind's early investors included several high-profile tech entrepreneurs. In 2014, Google purchased DeepMind for £400 million. Although most of the company has remained an independent entity based in London, DeepMind Health has since been directly incorporated into Google Health. Since the Google acquisition, the company has notched up a number of significant achievements, perhaps the most notable being the creation of AlphaGo, a program that defeated world champion Lee Sedol at the complex game of Go. Go had been considered a holy grail of AI, for its high number of possible board positions and resistance to existing programming techniques. However, AlphaGo beat European champion Fan Hui 5–0 in October 2015 before winning 4–1 against former world champion Lee Sedol in March 2016 and winning 3–0 against the world's top-ranked player Ke Jie in 2017. Additional DeepMind accomplishments include creating a neural Turing machine, reducing the energy used by the cooling systems in Google's data centres by 40%, and advancing research on AI safety. DeepMind has also been responsible for technical advances in machine learning, having produced a number of award-winning papers. In particular, the company has made significant advances in deep learning and reinforcement learning, and pioneered the field of deep reinforcement learning which combines these two methods. Hassabis has predicted that artificial intelligence will be "one of the most beneficial techn
GeneRIF
A GeneRIF or Gene Reference Into Function is a short (255 characters or fewer) statement about the function of a gene. GeneRIFs provide a simple mechanism for allowing scientists to add to the functional annotation of genes described in the Entrez Gene database. In practice, function is constructed quite broadly. For example, there are GeneRIFs that discuss the role of a gene in a disease, GeneRIFs that point the viewer towards a review article about the gene, and GeneRIFs that discuss the structure of a gene. However, the stated intent is for GeneRIFs to be about gene function. Currently over half a million geneRIFs have been created for genes from almost 1000 different species. GeneRIFs are always associated with specific entries in the Entrez Gene database. Each GeneRIF has a pointer to the PubMed ID (a type of document identifier) of a scientific publication that provides evidence for the statement made by the GeneRIF. GeneRIFs are often extracted directly from the document that is identified by the PubMed ID, very frequently from its title or from its final sentence. GeneRIFs are usually produced by NCBI indexers, but anyone may submit a GeneRIF. To be processed, a valid Gene ID must exist for the specific gene, or the Gene staff must have assigned an overall Gene ID to the species. The latter case is implemented via records in Gene with the symbol NEWENTRY. Once the Gene ID is identified, only three types of information are required to complete a submission: a concise phrase describing a function or functions (less than 255 characters in length, preferably more than a restatement of the title of the paper); a published paper describing that function, implemented by supplying the PubMed ID of a citation in PubMed; a valid e-mail address (which will remain confidential). == Example == Here are some GeneRIFs taken from Entrez Gene for GeneID 7157, the human gene TP53. The PubMed document identifiers have been omitted from the examples. Note the wide variability with respect to the presence or absence of punctuation and of sentence-initial capital letters. p53 and c-erbB-2 may have independent role in carcinogenesis of gall bladder cancer Degradation of endogenous HIPK2 depends on the presence of a functional p53 protein. p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1 Logistic regression analysis showed p53 and COX-2 as dependent predictors in pancreatic carcinogenesis, and a reciprocal relationship to neoplastic progression between p53 and COX-2. GeneRIFs are an unusual type of textual genre, and they have recently been the subject of a number of articles from the natural language processing community.
Buddhism and artificial intelligence
The relationship between Buddhist philosophy and artificial intelligence (AI) includes how principles such as the reduction of suffering and ethical responsibility may influence AI development. Buddhist scholars and philosophers have explored questions such as whether AI systems could be considered sentient beings under Buddhist definitions, and how Buddhist ethics might guide the design and application of AI technologies. Some Buddhist scholars, including Somparn Promta and Kenneth Einar Himma, have analyzed the ethical implications of AI, emphasizing the distinction between satisfying sensory desires and pursuing the reduction of suffering. Other thinkers, such as Thomas Doctor and colleagues, have proposed applying the Bodhisattva vow—a commitment to alleviate suffering for all sentient beings—as a guiding principle for AI system design. Buddhist scholars and ethicists have examined Buddhist ethical principles, such as nonviolence, in relation to AI, focusing on the need to ensure that AI technologies are not used to cause harm. == Context == === Sentient beings === A major goal in Buddhist philosophy is the removal of suffering for all sentient beings, an aspiration often referred to in the Bodhisattva vow. Discussions about artificial intelligence (AI) in relation to Buddhist principles have raised questions about whether artificial systems could be considered sentient beings or how such systems might be developed in ways that align with Buddhist concepts. Buddhists have varying opinions about AI sentience, but if AI systems are determined to be sentient under Buddhist definitions, their suffering would also need to be addressed and alleviated in accordance with the principles of Buddhist thought. == Buddhist principles in AI system design == === Nonviolence and AI === The broadest ethical concern is that artificial intelligence should align with the Buddhist principle of nonviolence. From this perspective, AI systems should not be designed or used to cause harm. === Instrumental and transcendental goals === Scholars Somparn Promta and Kenneth Einar Himma have argued that the advancement of artificial intelligence can only be considered instrumentally good, rather than good a priori, from a Buddhist perspective. They propose two main goals for AI designers and developers: to set ethical and pragmatic objectives for AI systems, and to fulfill these objectives in morally permissible ways. Promta and Himma identify two potential purposes for creating AI systems. The first is to fulfill our sensory desires and survival instincts, similar to other tools. They suggest that many AI developers implicitly prioritize this goal by focusing on technicalities rather than broader functionalities. The second, and more important goal according to Buddhist teachings, is to transcend these desires and instincts. In texts like the Brahmajāla Sutta and minor Malunkya Sutta, the Buddha emphasizes that sensory desires and survival instincts confine beings to suffering, and that eliminating suffering is the primary goal of human life. Promta and Himma argue that AI has the potential to assist humanity in transcending suffering by helping individuals overcome survival-driven instincts. === Intelligence as care === Thomas Doctor, Olaf Witkowski, Elizaveta Solomonova, Bill Duane, and Michael Levin propose redefining intelligence through the concept of "intelligence as care," and promote it as a slogan. Inspired by the Bodhisattva vow, they suggest this principle could guide AI system design. The Bodhisattva vow involves a formal commitment to alleviate suffering for all sentient beings, with four primary objectives: Liberating all beings from suffering. Extirpating all forms of suffering. Mastering endless techniques of practicing Dharma (Pali: dhammakkhandha, Sanskrit: dharmaskandha). Achieving ultimate enlightenment (Sanskrit: अनुत्तर सम्यक् सम्बोधि, Romanized: anuttara-samyak-saṃbodhi). This approach positions AI as a tool for exercising infinite care and alleviating stress and suffering for sentient beings. Doctor et al. emphasize that AI development should align with these altruistic principles.