James Frederick Allen (born 1950) is an American computational linguist recognized for his contributions to temporal logic, in particular Allen's interval algebra. He is interested in knowledge representation, commonsense reasoning, and natural language understanding, believing that "deep language understanding can only currently be achieved by significant hand-engineering of semantically-rich formalisms coupled with statistical preferences". He is the John H. Dessaurer Professor of Computer Science at the University of Rochester. == Biography == Allen received his Ph.D. from the University of Toronto in 1979, under the supervision of C. Raymond Perrault, after which he joined the faculty at Rochester. At Rochester, he was department chair from 1987 to 1990, directed the Cognitive Science Program from 1992 to 1996, and co-directed the Center for the Sciences of Language from 1996 to 1998. He served as the Editor-in-Chief of Computational Linguistics from 1983–1993. Since 2006 he has also been associate director of the Florida Institute for Human and Machine Cognition. == Academic life == === TRIPS project === The TRIPS project is a long-term research to build generic technology for dialogue (both spoken and 'chat') systems, which includes natural language processing, collaborative problem solving, and dynamic context-sensitive language modeling. This is contrast with the data driven approaches by machine learning, which requires to collect and annotate corpora, i.e. training data, firstly. === PLOW agent === PLOW agent is a system that learns executable task models from a single collaborative learning session, which integrates wide AI technologies including deep natural language understanding, knowledge representation and reasoning, dialogue systems, planning/agent-based systems, and machine learning. This paper won the outstanding paper award at AAAI in 2007. == Selected works == === Books === Allen is the author of the textbook Natural Language Understanding (Benjamin-Cummings, 1987; 2nd ed., 1995). He is also the co-author with Henry Kautz, Richard Pelavin, and Josh Tenenberg of Reasoning About Plans (Morgan Kaufmann, 1991). === Articles === 2007. PLOW: A Collaborative Task Learning Agent. (with Nathanael Chambers et al) AAAI'07 won the outstanding paper award at AAAI in 2007. 2006. Chester: Towards a Personal Medication Advisor. (with N. Blaylock, et al) Biomedical informatics 39(5) 1998. TRIPS: An Integrated Intelligent Problem-Solving Assistant. (with George Ferguson) AAAI'98 1983. Maintaining Knowledge about Temporal Intervals. CACM 26, 11, 832-843 == Awards and honors == In 1991 he was elected as a fellow of the Association for the Advancement of Artificial Intelligence (1990, founding fellow). In 1992 he became the Dessaurer Professor at Rochester.
MoFA Mitra
MoFA Mitra is a mobile application launched by the Ministry of Foreign Affairs of Nepal to provide digital consular services, emergency support, rescue coordination, and complaint registration facilities for Nepali citizens living and working abroad. The application allows Nepali migrant workers, students, tourists, and Non-Resident Nepalis (NRNs) to access embassy services, emergency help, and official information directly from their smartphones. == Background == The need for a centralized digital support platform for Nepalis abroad had been discussed for several years due to increasing complaints related to labor exploitation, rescue delays, documentation problems, and lack of communication with Nepali diplomatic missions. Media organizations and migrant rights advocates had continuously highlighted issues faced by Nepali workers abroad, including human trafficking, fraudulent recruitment, delayed repatriation, and difficulties in receiving emergency assistance. In response, the Ministry of Foreign Affairs developed the MoFA Mitra app to digitize complaint handling, improve communication between embassies and citizens, and make emergency response faster and more accessible. == Features == The app includes several services and features for Nepali citizens abroad, including complaint registration, rescue coordination, embassy communication, and digital consular support services. Features of the application include: Online complaint registration Emergency rescue request system Direct contact with Nepali embassies and consulates Digital consular information Passport and document-related assistance Labor and migration support information Emergency hotline access Real-time notifications and alerts Location-based embassy information Tracking and coordination support for stranded citizens According to reports, the application was designed to simplify access to diplomatic services and strengthen emergency response coordination for Nepalis abroad. == Launch == The application was officially launched by Nepal’s Ministry of Foreign Affairs in Kathmandu in May 2026. Government officials stated that the app would strengthen Nepal’s digital governance system and improve support mechanisms for Nepali citizens residing overseas. Officials said the platform would help improve communication between Nepali diplomatic missions and citizens during emergencies and rescue operations. == Reception == The launch of the app received positive coverage from Nepali and international media outlets. Commentators described the initiative as a significant step toward modernization of Nepal’s diplomatic and consular services and digital governance infrastructure. Some observers also emphasized the importance of effective implementation, rapid response mechanisms, and continuous monitoring to ensure practical benefits for migrant workers abroad.
ChipTest
ChipTest was a 1985 chess playing computer built by Feng-hsiung Hsu, Thomas Anantharaman and Murray Campbell at Carnegie Mellon University. It is the predecessor of Deep Thought which in turn evolved into Deep Blue. == History == ChipTest was based on a special VLSI-technology move generator chip developed by Hsu. ChipTest was controlled by a Sun-3/160 workstation and capable of searching approximately 50,000 moves per second. Hsu and Anantharaman entered ChipTest in the 1986 North American Computer Chess Championship, and it was only partially tested when the tournament began. It lost its first two rounds, but finished with an even score. In August 1987, ChipTest was overhauled and renamed ChipTest-M, M standing for microcode. The new version had eliminated ChipTest's bugs and was ten times faster, searching 500,000 moves per second and running on a Sun-4 workstation. ChipTest-M won the North American Computer Chess Championship in 1987 with a 4–0 sweep. ChipTest was invited to play in the 1987 American Open, but the team did not enter due to an objection by the HiTech team, also from Carnegie Mellon University. HiTech and ChipTest shared some code, and Hitech was already playing in the tournament. The two teams became rivals. Designing and implementing ChipTest revealed many possibilities for improvement, so the designers started on a new machine. Deep Thought 0.01 was created in May 1988 and the version 0.02 in November the same year. This new version had two customized VLSI chess processors and it was able to search 720,000 moves per second. With the "0.02" dropped from its name, Deep Thought won the World Computer Chess Championship with a perfect 5–0 score in 1989.
Agent Communications Language
Agent Communication Language (ACL) consists of computer communication protocols that are intended for AI agents to communicate with each other. In 2007, protocols of this nature were proposed which include: FIPA-ACL (by the Foundation for Intelligent Physical Agents, a standardization consortium) KQML (Knowledge Query and Manipulation Language) After the surge in Generative AI with the use of Transformers and Large language models, the definition of agent has shifted away from physical agents to signify software systems built using the principles of Agentic AI. A new protocol to emerge in this area is Natural Language Interaction Protocol (NLIP). NLIP is an application-level communication protocol defined between AI Agents or between a human and an AI agent. Ecma International; a standards body which develops and publishes international standards for the information and communication industry; published on 10 December 2025 five new standards and one technical report defining the Natural Language Interaction Protocol (NLIP). As a result, we can define agent communication protocols into two categories: ontology based agent communication protocols and generative AI based agent communication protocols. Ontology based agent communication protocols use a common ontology to be used between agents. An ontology is a part of the agent's knowledge base that describes what kind of things an agent can deal with and how they are related to each other. FIPA-ACL and KQML are examples of such protocols. These protocols rely on speech act theory developed by Searle in the 1960s and enhanced by Winograd and Flores in the 1970s. They define a set of performatives, also called Communicative Acts, and their meaning (e.g. ask-one). The content of the performative is not standardized, but varies from system to system. Implementation support of FIPA-ACL is included in FIPA-OS and Jade. Generative AI based agent communication protocols such as NLIP do not require a shared ontology among communicating agents. In its stead, they use generative AI models to translate natural language text, images, videos or other modalities of data into a local ontology. This provides for hot-extensibility where the same protocol can be used for multiple communication needs, and simplifies version control since different agents can use different versions of a shared ontology. NLIP has been designed with security considerations in mind. The specification and standards comprising NLIP are developed and maintained by Ecma Technical Community 56.
Future of Life Institute
The Future of Life Institute (FLI) is a nonprofit organization which aims to steer transformative technology towards benefiting life and away from large-scale risks, with a focus on existential risk from advanced artificial intelligence (AI). FLI's work includes grantmaking, educational outreach, and advocacy within the United Nations, United States government, and European Union institutions. The founders of the Institute include MIT cosmologist Max Tegmark, UCSC cosmologist Anthony Aguirre, and Skype co-founder Jaan Tallinn. == Purpose == FLI's stated mission is to steer transformative technology towards benefiting life and away from large-scale risks. FLI's philosophy focuses on the potential risk to humanity from the development of human-level or superintelligent artificial general intelligence (AGI), but also works to mitigate risk from biotechnology, nuclear weapons and global warming. == History == === Founding === FLI was founded in March 2014 by MIT cosmologist Max Tegmark, Skype co-founder Jaan Tallinn, DeepMind research scientist Viktoriya Krakovna, Tufts University postdoctoral scholar Meia Chita-Tegmark, and UCSC physicist Anthony Aguirre. === Activism === Starting in 2017, FLI has offered an annual "Future of Life Award", with the first awardee being Vasili Arkhipov. The same year, FLI released Slaughterbots, a short arms-control advocacy film. FLI released a sequel in 2021. In 2018, FLI drafted a letter calling for "laws against lethal autonomous weapons". Signatories included Elon Musk, Demis Hassabis, Shane Legg, and Mustafa Suleyman. In January 2023, Swedish magazine Expo reported that the FLI had offered a grant of $100,000 to a foundation set up by Nya Dagbladet, a Swedish far-right online newspaper. In response, Tegmark said that the institute had only become aware of Nya Dagbladet's positions during due diligence processes a few months after the grant was initially offered, and that the grant had been immediately revoked. === Open letter on an AI pause === In March 2023, FLI published a letter titled "Pause Giant AI Experiments: An Open Letter". This called on major AI developers to agree on a verifiable six-month pause of any systems "more powerful than GPT-4" and to use that time to institute a framework for ensuring safety; or, failing that, for governments to step in with a moratorium. The letter said: "recent months have seen AI labs locked in an out-of-control race to develop and deploy ever more powerful digital minds that no-one - not even their creators - can understand, predict, or reliably control". The letter referred to the possibility of "a profound change in the history of life on Earth" as well as potential risks of AI-generated propaganda, loss of jobs, human obsolescence, and society-wide loss of control. Prominent signatories of the letter included Elon Musk, Steve Wozniak, Evan Sharp, Chris Larsen, and Gary Marcus; AI lab CEOs Connor Leahy and Emad Mostaque; politician Andrew Yang; deep-learning researcher Yoshua Bengio; and Yuval Noah Harari. Marcus stated "the letter isn't perfect, but the spirit is right." Mostaque stated, "I don't think a six month pause is the best idea or agree with everything but there are some interesting things in that letter." In contrast, Bengio explicitly endorsed the six-month pause in a press conference. Musk predicted that "Leading AGI developers will not heed this warning, but at least it was said." Some signatories, including Musk, said they were motivated by fears of existential risk from artificial general intelligence. Some of the other signatories, such as Marcus, instead said they signed out of concern about risks such as AI-generated propaganda. The authors of one of the papers cited in FLI's letter, "On the Dangers of Stochastic Parrots: Can Language Models Be Too Big?" including Emily M. Bender, Timnit Gebru, and Margaret Mitchell, criticised the letter. Mitchell said that “by treating a lot of questionable ideas as a given, the letter asserts a set of priorities and a narrative on AI that benefits the supporters of FLI. Ignoring active harms right now is a privilege that some of us don’t have.” === Open letter on prohibiting superintelligence === In October 2025, another letter, the "Statement on Superintelligence", was published. It called for a prohibition on the development of superintelligence not lifted before there is "broad scientific consensus that it will be done safely and controllably" and "strong public buy-in". FLI director Anthony Aguirre explained that "time is running out", expecting that the technology could arrive in as little as one to two years and counting on "widespread realization among society at all its levels" to stop it. He added that "whether it's soon or it takes a while, after we develop superintelligence, the machines are going to be in charge" and "that is not an experiment that we want to just run toward". The list of signatories included Nobel laureates Geoffrey Hinton, Daron Acemoglu, Beatrice Fihn, Frank Wilczek and John C. Mather as well as Hinton's fellow "godfather" of modern AI Yoshua Bengio, Steve Wozniak, Steve Bannon, Paolo Benanti, Prince Harry, Duke of Sussex and Meghan, Duchess of Sussex. The letter was also signed by the actors Joseph Gordon-Levitt and Stephen Fry, rapper Will.i.am and author Yuval Noah Harari. Former national security advisor Susan Rice, and OpenAI member of technical staff Leo Gao also signed their names to the letter. Polling released alongside the letter showed that 64% of American agreed that superintelligence "shouldn't be developed until it's provably safe and controllable" and only 5% believed it should be developed as quickly as possible. == Operations == === Advocacy === FLI has actively contributed to policymaking on AI. In October 2023, for example, U.S. Senate majority leader Chuck Schumer invited FLI to share its perspective on AI regulation with selected senators. In Europe, FLI successfully advocated for the inclusion of more general AI systems, such as GPT-4, in the EU's Artificial Intelligence Act. In military policy, FLI coordinated the support of the scientific community for the Treaty on the Prohibition of Nuclear Weapons. At the UN and elsewhere, the institute has also advocated for a treaty on autonomous weapons. === Research grants === The FLI research program started in 2015 with an initial donation of $10 million from Elon Musk. In this initial round, a total of $7 million was awarded to 37 research projects. In July 2021, FLI announced that it would launch a new $25 million grant program with funding from the Russian–Canadian programmer Vitalik Buterin. === Conferences === In 2014, the Future of Life Institute held its opening event at MIT: a panel discussion on "The Future of Technology: Benefits and Risks", moderated by Alan Alda. The panelists were synthetic biologist George Church, geneticist Ting Wu, economist Andrew McAfee, physicist and Nobel laureate Frank Wilczek and Skype co-founder Jaan Tallinn. Since 2015, FLI has organised biannual conferences with the stated purpose of bringing together AI researchers from academia and industry. As of April 2023, the following conferences have taken place: "The Future of AI: Opportunities and Challenges" conference in Puerto Rico (2015). The stated goal was to identify promising research directions that could help maximize the future benefits of AI. At the conference, FLI circulated an open letter on AI safety which was subsequently signed by Stephen Hawking, Elon Musk, and many artificial intelligence researchers. The Beneficial AI conference in Asilomar, California (2017), a private gathering of what The New York Times called "heavy hitters of A.I." (including Yann LeCun, Elon Musk, and Nick Bostrom). The institute released a set of principles for responsible AI development that came out of the discussion at the conference, signed by Yoshua Bengio, Yann LeCun, and many other AI researchers. These principles may have influenced the regulation of artificial intelligence and subsequent initiatives, such as the OECD Principles on Artificial Intelligence. The beneficial AGI conference in Puerto Rico (2019). The stated focus of the meeting was answering long-term questions with the goal of ensuring that artificial general intelligence is beneficial to humanity. == In the media == "The Fight to Define When AI is 'High-Risk'" in Wired. "Lethal Autonomous Weapons exist; They Must Be Banned" in IEEE Spectrum. "United States and Allies Protest U.N. Talks to Ban Nuclear Weapons" in The New York Times. "Is Artificial Intelligence a Threat?" in The Chronicle of Higher Education, including interviews with FLI founders Max Tegmark, Jaan Tallinn and Viktoriya Krakovna. "But What Would the End of Humanity Mean for Me?", an interview with Max Tegmark on the ideas behind FLI in The Atlantic.
Local coordinates
Local coordinates are the ones used in a local coordinate system or a local coordinate space. Simple examples: Houses. In order to work in a house construction, the measurements are referred to a control arbitrary point that will allow to check it: stick/sticks on the ground, steel bar, nails... Addresses. Using house numbers to locate a house on a street; the street is a local coordinate system within a larger system composed of city townships, states, countries, postal codes, etc. Local systems exist for convenience. On ancient times, every work was made on relative bases as there was no conception of global systems. Practically, it is better to use local systems for small works as houses, buildings... For most of the applications, it is desired the position of one element relative to one building or location, and in a more local way, relative to one furniture or person. In a regular way, you will not give your position by geographical coordinates rather than "I am 15 meters away of the entry to the building". So it is a pretty common way to locate things. It is possible to bring latitude and longitude for all terrestrial locations, but unless one has a highly precise GPS device or you make astronomical observations, this is impractical. It is much simpler to use a tape, a rope, a chain... The position information (global) should be transformed into a location. Position refers to a numeric or symbolic description within a spatial reference system, whereas location refers to information about surrounding objects and their interrelationships. (Topological space) == Use == In computer graphics and computer animation, local coordinate spaces are also useful for their ability to model independently transformable aspects of geometrical scene graphs. When modeling a car, for example, it is desirable to describe the center of each wheel with respect to the car's coordinate system, but then specify the shape of each wheel in separate local spaces centered about these points. This way, the information describing each wheel can be simply duplicated four times, and independent transformations (e.g., steering rotation) can be similarly effected. Bounding volumes of objects may be described more accurately using extents in the local coordinates, (i.e. an object oriented bounding box, contrasted with the simpler axis aligned bounding box). The trade-off for this flexibility is additional computational cost: the rendering system must access the higher-level coordinate system of the car and combine it with the space of each wheel in order to draw everything in its proper place. Local coordinates also afford digital designers a means around the finite limits of numerical representation. The tread marks on a tire, for example, can be described using millimeters by allowing the whole tire to occupy the entire range of numeric precision available. The larger aspects of the car, such as its frame, might be described in centimeters, and the terrain that the car travels on could be specified in meters. In differential topology, local coordinates on a manifold are defined by means of an atlas of charts. The basic idea behind coordinate charts is that each small patch of a manifold can be endowed with a set of local coordinates. These are collected together into an atlas, and stitched together in such a way that they are self-consistent on the manifold. In Cartography and Maps, the traditional way of works are local datum. With a local datum the land can be mapped on relative small areas as a country. With the need of global systems, the transformations on between datum became a problem, so geodetic datum have been created. More than 150 local datum have been used in the world.
Minimum information standard
Minimum information standards are sets of guidelines and formats for reporting data derived by specific high-throughput methods. Their purpose is to ensure the data generated by these methods can be easily verified, analysed and interpreted by the wider scientific community. Ultimately, they facilitate the transfer of data from journal articles (unstructured data) into databases (structured data) in a form that enables data to be mined across multiple data sets. Minimal information standards are available for a vast variety of experiment types including microarray (MIAME), RNAseq (MINSEQE), metabolomics (MSI) and proteomics (MIAPE). Minimum information standards typically have two parts. Firstly, there is a set of reporting requirements – typically presented as a table or a checklist. Secondly, there is a data format. Information about an experiment needs to be converted into the appropriate data format for it to be submitted to the relevant database. In the case of MIAME, the data format is provided in spreadsheet format (MAGE-TAB). Some of the communities that maintain minimum information standards also provide tools to help experimental researchers to annotate their data. == MI Standards == The individual minimum information standards are brought by the communities of cross-disciplinary specialists focused on the problematic of the specific method used in experimental biology. The standards then provide specifications what information about the experiments (metadata) is crucial and important to be reported together with the resultant data to make it comprehensive. The need for this standardization is largely driven by the development of high-throughput experimental methods that provide tremendous amounts of data. The development of minimum information standards of different methods is since 2008 being harmonized by "Minimum Information about a Biomedical or Biological Investigation" (MIBBI) project. === MIAPPE, Minimum Information About a Plant Phenotyping Experiment === MIAPPE is an open, community driven project to harmonize data from plant phenotyping experiments. MIAPPE comprises both a conceptual checklist of metadata required to adequately describe a plant phenotyping experiment. === MIQE, Minimum Information for Publication of Quantitative Real-Time PCR Experiments === Published in 2009 these guidelines for the basis of requirements by many journals when submitting QPCR data, sadly they are not adhered to enough. === MIAME, gene expression microarray === Minimum Information About a Microarray Experiment (MIAME) describes the Minimum Information About a Microarray Experiment that is needed to enable the interpretation of the results of the experiment unambiguously and potentially to reproduce the experiment and is aimed at facilitating the dissemination of data from microarray experiments. It was published by the FGED Society in 2001 and was the first published minimum information standard for high-throughput experiments in the life sciences. MIAME contains a number of extensions to cover specific biological domains, including MIAME-env, MIAME-nut and MIAME-tox, covering environmental genomics, nutritional genomics and toxogenomics, respectively. === MINI: Minimum Information about a Neuroscience Investigation === ==== MINI: Electrophysiology ==== Electrophysiology is a technology used to study the electrical properties of biological cells and tissues. Electrophysiology typically involves the measurements of voltage change or electric current flow on a wide variety of scales from single ion channel proteins to whole tissues. This document is a single module, as part of the Minimum Information about a Neuroscience investigation (MINI) family of reporting guideline documents, produced by community consultation and continually available for public comment. A MINI module represents the minimum information that should be reported about a dataset to facilitate computational access and analysis to allow a reader to interpret and critically evaluate the processes performed and the conclusions reached, and to support their experimental corroboration. In practice a MINI module comprises a checklist of information that should be provided (for example about the protocols employed) when a data set is described for publication. The full specification of the MINI module can be found here. === MIARE, RNAi experiment === Minimum Information About an RNAi Experiment (MIARE) is a data reporting guideline which describes the minimum information that should be reported about an RNAi experiment to enable the unambiguous interpretation and reproduction of the results. === MIACA, cell based assay === Advances in genomics and functional genomics have enabled large-scale analyses of gene and protein function by means of high-throughput cell biological analyses. Thereby, cells in culture can be perturbed in vitro and the induced effects recorded and analyzed. Perturbations can be triggered in several ways, for instance with molecules (siRNAs, expression constructs, small chemical compounds, ligands for receptors, etc.), through environmental stresses (such as temperature shift, serum starvation, oxygen deprivation, etc.), or combinations thereof. The cellular responses to such perturbations are analyzed in order to identify molecular events in the biological processes addressed and understand biological principles. We propose the Minimum Information About a Cellular Assay (MIACA) for reporting a cellular assay, and CA-OM, the modular cellular assay object model, to facilitate exchange of data and accompanying information, and to compare and integrate data that originate from different, albeit complementary approaches, and to elucidate higher order principles. Documents describing MIACA are available and provide further information as well as the checklist of terms that should be reported. === MIAPE, proteomic experiments === The Minimum Information About a Proteomic Experiment documents describe information which should be given along with a proteomic experiment. The parent document describes the processes and principles underpinning the development of a series of domain specific documents which now cover all aspects of a MS-based proteomics workflow. === MIMIx, molecular interactions === This document has been developed and maintained by the Molecular Interaction worktrack of the HUPO-PSI (www.psidev.info) and describes the Minimum Information about a Molecular Interaction experiment. === MIAPAR, protein affinity reagents === The Minimum Information About a Protein Affinity Reagent has been developed and maintained by the Molecular Interaction worktrack of the HUPO-PSI (www.psidev.info)in conjunction with the HUPO Antibody Initiative and a European consortium of binder producers and seeks to encourage users to improve their description of binding reagents, such as antibodies, used in the process of protein identification. === MIABE, bioactive entities === The Minimum Information About a Bioactive Entity was produced by representatives from both large pharma and academia who are looking to improve the description of usually small molecules which bind to, and potentially modulate the activity of, specific targets in a living organism. This document encompasses drug-like molecules as well as herbicides, pesticides and food additives. It is primarily maintained through the EMBL-EBI Industry program (www.ebi.ac.uk/industry). === MIGS/MIMS, genome/metagenome sequences === This specification is being developed by the Genomic Standards Consortium === MIFlowCyt, flow cytometry === === Minimum Information about a Flow Cytometry Experiment === The Minimum Information about a Flow Cytometry Experiment (MIFlowCyt) is a standard related to flow cytometry which establishes criteria to record information on experimental overview, samples, instrumentation and data analysis. It promotes consistent annotation of clinical, biological and technical issues surrounding a flow cytometry experiment. === MINDR, dual gene expression reporters === Requires (1) reporting absolute values of reporter readouts, (2) list of positive and negative controls, and (3) sequences of all reporter constructs. === MISFISHIE, In Situ Hybridization and Immunohistochemistry Experiments === === MIAPA, Phylogenetic Analysis === Criteria for Minimum Information About a Phylogenetic Analysis were described in 2006. === MIRAGE, Glycomics === The MIRAGE project is supported and coordinated by the Beilstein-Institut to establish guidelines for data handling and processing in glycomics research [1] === MIAO, ORF === === MIAMET, METabolomics experiment === === MIAFGE, Functional Genomics Experiment === === MIRIAM, Minimum Information Required in the Annotation of Models === The Minimal Information Required In the Annotation of Models (MIRIAM), is a set of rules for the curation and annotation of quantitative models of biological systems. === MIASE, Minimum Information About a Simulation Experiment =