The Verlag Europa-Lehrmittel Nourney, Vollmer GmbH & Co. KG (English: European educational media), based in Haan (district Gruiten) near Düsseldorf, Germany, develops educational media for vocational training and further education as used in vocational schools, universities, companies and further education institutions for industrial-technical, business, social, health as well as gastronomic professions. The contents are delivered in print as well as in digital formats, including offered as apps, simulations, software and through an exam preparation portal. The publisher has its own digital learning platform, the Europathek. General partner is Nourney, Vollmer & Co. GmbH, a school and specialist book publisher. == History == The publishing house was founded in Wuppertal in 1948, when the first books were published. In Eislingen/Fils a construction office was set up to create the technical drawings for the textbooks - today the drawing office of the publisher in Ostfildern. A little over 40 years later, in 1989, a new company building was built in Haan-Gruiten. In 1997, Europa-Lehrmittel acquired the Fachbuchverlag Pfanneberg with its program aimed at gastronomic professions. Further program expansions in vocational training were realized by adding titles of the publishing houses Lau, Gerber, Pluspunkt, parts of the Verlag Handwerk und Technik program and that of the Gildebuchverlag. In 2013, the scientific and technical university titles of Verlag Harri Deutsch were taken over, including the bestselling "Handbook of Mathematics" by Ilya Nikolaevich Bronstein and Konstantin Adolfovic Semendyayev. In addition, Europa-Lehrmittel's first exam apps appeared. In 2017, the publisher introduced its own digital learning platform named Europathek. The Prüfungsdoc (English: Examination Doc) platform, which enables targeted online preparation for exams, went online the same year. In 2018, the titles of the Düsseldorf publishing house SOL for self-organized learning were incorporated into Europa-Lehrmittel's program. == Program == The program meanwhile includes well over 2000 print and digital publications, including specialist titles on metal technology, automotive and electrical engineering (like "Tabellenbuch Metall" (English: Metal Book of Tables)), on business administration, as well as works for the gastronomic profession (e.g. "Der junge Koch" (English: The Young Cook)). Many titles also appear as licensed editions in over 20 different languages on all continents. All contents are presented in an annual catalog, on the website, in schools, in companies, and at trade fairs and congresses. The publisher is a member of the Deutscher Hauswirtschaftsrat. == Digital educational media == Europathek: In addition to digital books, Europathek also provides media packages, additional materials and e-learning contents. The online contents of the 'media shelf' can be used per web browser. There are also software versions and apps for offline use, with the help of which the obtained titles can be viewed after downloading. Prüfungsdoc (English: Examination Doc): Prüfungsdoc offers web-based learning, practice and repetition to prepare for the intermediate and final examinations. This includes simulations of the exams with direct evaluation of the results.
Biomedical data science
Biomedical data science is a multidisciplinary field which leverages large volumes of data to promote biomedical innovation and discovery. Biomedical data science draws from various fields including Biostatistics, Biomedical informatics, and machine learning, with the goal of understanding biological and medical data. It can be viewed as the study and application of data science to solve biomedical problems. Modern biomedical datasets often have specific features which make their analyses difficult, including: Large numbers of feature (sometimes billions), typically far larger than the number of samples (typically tens or hundreds) Noisy and missing data Privacy concerns (e.g., electronic health record confidentiality) Requirement of interpretability from decision makers and regulatory bodies Many biomedical data science projects apply machine learning to such datasets. These characteristics, while also present in many data science applications more generally, make biomedical data science a specific field. Examples of biomedical data science research include: Computational genomics Computational imaging Electronic health records data mining Biomedical network science Clinical Natural Language Processing (NLP) == Computational Imaging and Deep Learning == Computational imaging is a cornerstone of biomedical data science, focusing on the development of algorithms to enhance, analyze, and interpret medical imagery. In recent years, the field has been transformed by the integration of deep learning, particularly through the use of Convolutional Neural Networks. Deep learning started from researchers manually defining characteristics like edge detection or texture representation learning. In a more modern approach of computational imaging, models automatically learn a hierarchy of features directly from raw pixel data. This overlap between data science and deep learning is applied across several key tasks: Classification: Identifying the presence of specific diseases, such as distinguishing between benign and malignant tumors in histopathology slides or detecting pneumonia in chest X-rays. Segmentation: The precise delineation of anatomical structures or lesions. A notable example is the U-Net architecture, which is widely used for biomedical image segmentation to help clinicians quantify organ volume or track tumor growth. Detection: Automating the localization of small objects, such as identifying microcalcifications in mammograms or polyps during colonoscopies. Registration: The process of aligning multiple images to provide a comprehensive view of the patient's anatomy. Even with all of these enhancements, the application of deep learning in medical imaging requires accomplishing vigorous challenges. An example of these changes is building large, annotated datasets and creating the imperative for model interpretability in clinical decision-making. == Electronic Health Records == Electronic Health Records (EHRs) are a digital alternative to patient paper charts, usually including individual records or population health information. EHRs can be used in a wide variety of applications, including research and analysation as they often include demographics, diagnoses, medications, test results, and personal statistics. === History === ==== 1960s ==== The earliest precursor is considered Dr. Lawrence Weed's problem-oriented medical record (POMR) published in the 1968 which sorts and groups medical records by medical diagnoses and symptoms. The POMR was the first system to organize based off of patient information rather than the source (doctors, nurses, attendings, etc.). In 1969, the Regenstrief Institute developed and published the Regenstrief Medical Record System which established electronic writing, storage, and retrieval of records which served as the basis for modern EHR systems. ==== 2000s ==== In 2009, the Health Information Technology for Economic and Clinical Health Act (HITECH Act) was passed in the United States. This act standardized privacy and distribution of EHRs and increased the acceptance and utilization of EHRs within medical and academic settings. == Artificial Intelligence and Machine Learning Applications == Machine Learning and Artificial Intelligence have become central tools in biomedical data science. Recent advances in large language models (LLMs) have expanded their role beyond text, with models trained directly on genomic sequences enabling tasks such as gene function prediction, variant effect analysis, and drug discovery. In clinical settings, Natural Language Processing (NLP) models are applied to electronic health records to extract structured insights from unstructured clinical notes and data, supporting diagnosis and treatment planning. Beyond genomics, AI models have been applied to protein structure prediction. AlphaFold, developed by Google DeepMind, uses deep learning to predict three-dimensional protein structures from amino acid sequences with high accuracy. These predictions have been used to support drug target identification and the study of disease mechanisms. == Knowledge Graphs == Knowledge graphs (KGs) are widely used in biomedical data science to represent and analyze complex relationships among biological and medical entities. By structuring data as nodes (e.g., genes, diseases, drugs) and edges (relationships), KGs enable computational methods to extract insights and support decision-making. These biomedical relationships can be efficiently modeled and queried using technologies such as Neo4j. === Biomedical Research Applications === KGs provide biomedical researchers with a way to model complex biological systems. They have been used to identify the relationships between diseases and biomolecules, support drug repurposing, and to uncover new biological insights. Additional applications include: Identification of novel antibiotic resistance genes through graph-based link prediction. Finding associations between miRNA and diseases. Prediction of protein-protein interactions. === Clinical Applications === In clinical settings, KGs can be used to make visual representations of a patient's electronic health records. The data obtained from these graphs can assist healthcare providers in improving patient diagnoses and prescribing more effective drugs. Additionally, embeddings derived from resources like the Unified Medical Language System (UMLS) enable natural language processing of clinical text and similarity analysis between medical concepts. === Limitations === Despite their advantages, knowledge graphs face several challenges. Some of these include: High algorithmic complexity and large biological datasets make the process computationally expensive. KG construction can be a time-consuming process that requires careful attention to assign appropriate node types and vocabularies. Using data from a wide range of datasets in one KG requires them to be effectively integrated. == Privacy == A primary challenge in biomedical data science is maintaining medical privacy. Conducting research requires that data be collected on a number of people for training and testing purposes and is stored within biomedical datasets. This poses a risk for violating patient confidentiality and may dissuade people from participating in studies. The main sources of health statistics are surveys administrative and medical records health care claims data, vital records surveillance disease registries grey literature and peer-reviewed literature. Large data collection is a useful tool for researching various medical conditions. Researchers use these large datasets of information to identify factors that may make people more susceptible to certain diseases. Large amounts of collected data can help researchers identify patterns for disease probabilities. The findings can show a person is more likely for a condition, or identify environmental, social, and personal habits that may lead to adverse health issues. Institutions researching using personal medical information come with a moral and legal responsibility to protect the use of that information. Protection of the collected information has become a big concern. Sophisticated and coordinated attacks on certain medical systems happen more frequently. Medical companies, medical insurance and private businesses have invested a great deal into the protection of personal data. Despite this, data breaches continue to be documented. The chart below shows the top healthcare breaches in 2025. For these reasons, many people have reservations about giving up their personal data. Aside from the legitimate use of personal data there have been instances where companies have found methods to profit from brokering medical information. Concerns exist regarding unauthorized use of sensitive information within these data companies. If a person is identified within a dataset, then sensitive data can be used to discriminate against them. For example, insurance companies may charge a hi
Roadie (app)
Roadie Inc. is an American package delivery company for business and private same-day, urgent and scheduled delivery in the United States. The company was founded in 2014 and launched its web and mobile apps in January 2015. As of September 2021, it reported having over 200,000 drivers covering more than 20,000 zip codes. Roadie states it matches gig drivers with deliveries that are directed along the routes they plan to travel. Major customers include The Home Depot, Walmart, Tractor Supply Company, Best Buy and Delta Air Lines. In September 2021, UPS entered into an agreement to acquire Roadie for an undisclosed amount with the transaction expected to be closed in the fourth quarter. == History == Roadie was founded by Marc Gorlin, a co-founder of Kabbage and founder of VerticalOne and Pretty Good Privacy, as a same-day and urgent delivery company in 2014. In January 2015, Roadie launched the first consumer to consumer (C2C) version of its app with a Series A funding round of $10 million. In February, Roadie announced a partnership with Waffle House to designate its restaurants "Roadie Roadhouses", offering a neutral meeting place for drivers and senders. Drivers receive free food and drink through the partnership. In May, late-night host Jimmy Kimmel discussed the Roadie-Waffle House relationship in an opening monologue on Jimmy Kimmel Live!. Roadie's driver network expanded significantly as a result. Roadie closed a Series B round of funding in June, raising $15 million, and its first business to business (B2B) app version launched that November. In 2015, Delta Air Lines signed an agreement with Roadie to deliver mishandled luggage, becoming Roadie’s first enterprise customer. Roadie launched a pilot program with Delta at Daytona Beach International Airport. Since then, the relationship has expanded to include over 70 airports around the United States and a first mile/last mile line haul relationship with Delta Cargo. In 2017, the company signed a deal with The Home Depot, also based in Atlanta, and in February 2019, closed a Series C round of funding. In October 2019, Roadie and Delta Cargo announced a partnership to create a same-day cross-country delivery offering, DASH Door-to-Door, the first of its kind from a U.S. passenger airline. Tractor Supply Company became the first general merchandise retailer to offer same-day delivery from every store in April 2020 through Roadie. In September 2021, UPS entered an agreement to acquire Roadie for an undisclosed amount. The transaction was expected to close in the fourth quarter of 2021. Roadies, which at the time reported having 200,000 operators serving over 20,000 ZIP Codes, was expected to continue operations under its name as a separate company with no transfer of packages between the UPS and Roadies networks. The relationship between the companies goes back several years with UPS being an early investor. Earlier in 2021, UPS had begun a pilot program testing same-day deliveries via Roadies. == Operations == === On-the-way model === Roadie’s app works by connecting drivers with senders, businesses or consumers who have items that need to be delivered. Deliveries within the app are referred to as "Gigs", which Gorlin said was inspired by live music road crews, also known as roadies. A sender creates a Gig on Roadie's web app or via its API. Drivers then review deliveries in their area on their mobile app and may choose to offer to take on individual or groups of deliveries along the same route. Gigs are then assigned to drivers by Roadie's algorithm. According to the company, this model encourages drivers to choose Gigs that align with their planned schedules and routes. Roadie calls this its "on-the-way" delivery model. The go-to-market approach taken by Roadie also differs from its competitors. Rather than launching in major cities and sequentially adding new markets city-by-city, Roadie launched nationwide from its inception. The company relies on retail and airline partners to drive volume of deliveries in individual markets, which in turn builds up a network of drivers in those areas, making it easier for small businesses and consumers to send deliveries as well. This strategy allows Roadie to reach smaller cities and towns in rural or exurban communities, traditionally difficult markets for delivery providers to serve. === Service lines === Roadie’s platform is most popular for same-day, on-demand or scheduled first mile/last mile delivery, especially delivery from stores and warehouses. Some retailers also use it for returns and reverse logistics, moving inventory, and hot shot shipping. Roadie operates 1-hour grocery delivery for Walmart, and delivers perishable food items for others including small, independent retailers. The on-the-way model complements the grocery industry’s just in time model, making last-mile deliveries that do not break the cold chain. === Cross-country same-day delivery === In October 2019, Roadie and Delta Cargo launched DASH Door-to-Door, a 24/7 door-to-door pick-up and delivery service. Roadie handles the first and last mile and Delta manages the line haul via passenger flights. The service launched originally from Atlanta to 55 cities and is an industry-first for a US commercial airline. === Promotion, awards and corporate citizenship === In September 2015, Roadie announced a partnership with Atlanta-based musician Ludacris, to promote the app. Following the devastation caused by flooding in Baton Rouge in 2016, Roadie offered free pickup and delivery for all deliveries traveling to and from the Baton Rouge area. In December 2020, Walmart named Roadie its top delivery partner for "Highest Driver Customer Satisfaction" and "Highest Net Promoter Score", after expanding into general merchandise deliveries as well as grocery that same year.
TU Me
TU (formerly TU Me) is a digital platform developed by Telefónica and operated through its subsidiary Telefónica Innovación Digital. Initially launched in 2012 as a messaging app under the name TU Me, the brand was later revived in 2024 to designate a new suite of digital products focused on privacy, cybersecurity, and digital identity. == TU Me (2012–2014) == TU Me was a free mobile application released by Telefónica in May 2012. It allowed users to make voice calls, send texts, share photos and locations, and store conversation history in the cloud. The app was available for iOS and Android platforms, positioned as an alternative to services like WhatsApp and Viber. Despite early interest, TU Me was discontinued a few years later and removed from major app stores. Telefónica did not continue development of this version beyond its initial release cycle. == TU (2024–present) == In January 2024, Telefónica relaunched the brand TU through its technology subsidiary Telefónica Innovación Digital. Unlike its predecessor, the new TU is not a messaging app but a digital product platform offering solutions in cybersecurity, identity management, and cryptographic technology. The project includes a range of services built with technologies such as artificial intelligence, blockchain, and post-quantum cryptography. It operates independently from Movistar and targets both individual users and businesses. Notable products include: Latch: a digital access control system for securing user accounts. VerifAI: an AI-based tool for detecting manipulated media (images, audio, video). Metashield: software to identify and remove hidden metadata in documents. Wallet: a digital wallet for managing crypto-assets. Quantum Drop: encrypted file transfer system using post-quantum technology. Quantum Encryption: a security tool for IoT and private networks. Gallery: a blockchain-based digital art marketplace.
Generatrix
In geometry, a generatrix () or describent is a point, curve or surface that, when moved along a given path, generates a new shape. The path directing the motion of the generatrix motion is called a directrix or dirigent. == Examples == A cone can be generated by moving a line (the generatrix) fixed at the future apex of the cone along a closed curve (the directrix); if that directrix is a circle perpendicular to the line connecting its center to the apex, the motion is rotation around a fixed axis and the resulting shape is a circular cone. The generatrix of a cylinder, a limiting case of a cone, is a line that is kept parallel to some axis.
Aikuma
Aikuma is an Android app for collecting speech recordings with time-aligned translations. The app includes a text-free interface for consecutive interpretation, designed for users who are not literate. The Aikuma won Grand Prize in the Open Source Software World Challenge (2013). == Name == Aikuma means "meeting place" in Usarufa, a Papuan language where this software was first used in 2012. == History == Aikuma was developed with sponsorship from the National Science Foundation, including a $101,501 (US) project, "to use mobile telephones to collect larger amounts of data on undocumented endangered languages than would never be possible through usual fieldwork." Aikuma and its modified version (Lig-Aikuma) have been used for collecting substantial quantities of audio in remote indigenous villages. A modified version of the app, called Lig-Aikuma, has been developed at the Université Grenoble Alpes (LIG laboratory) and implements new features such as elicitation of speech from text, images and videos. == Similar Software == Lingua Libre is an online collaborative project and tool by the Wikimedia France association, which can be used as a tool for Language Preservation. Lingua Libre enables to record words, phrases, or sentences of any language, oral (audio recording) or signed (video recording). It is a highly efficient method to record endangered languages since up to 1000 words can be recorded per hour. All the content is under Free License, and speakers of minority languages are encouraged to record their own dialects.
Nobody (username)
In many Unix variants, "nobody" is the conventional name of a user identifier which owns no files, is in no privileged groups, and has no abilities except those which every other user has. It is normally not enabled as a user account, i.e. has no home directory or login credentials assigned. Some systems also define an equivalent group "nogroup". == Uses == The pseudo-user "nobody" and group "nogroup" are used, for example, in the NFSv4 implementation of Linux by idmapd, if a user or group name in an incoming packet does not match any known username on the system. It was once common to run daemons as nobody, especially on servers, in order to limit the damage that could be done by a malicious user who gained control of them. However, the usefulness of this technique is reduced if more than one daemon is run like this, because then gaining control of one daemon would provide control of them all. The reason is that processes owned by the same user have the ability to send signals to each other and use debugging facilities to read or even modify each other's memory. Modern practice, as recommended by the Linux Standard Base, is to create a separate user account for each daemon.