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  • Deep tomographic reconstruction

    Deep tomographic reconstruction

    Deep Tomographic Reconstruction is a set of methods for using deep learning methods to perform tomographic reconstruction of medical and industrial images. It uses artificial intelligence and machine learning, especially deep artificial neural networks or deep learning, to overcome challenges such as measurement noise, data sparsity, image artifacts, and computational inefficiency. This approach has been applied across various imaging modalities, including CT, MRI, PET, SPECT, ultrasound, and optical imaging == Historical background == Traditional tomographic reconstruction relies on analytic methods such as filtered back-projection, or iterative methods which incrementally compute inverse transformations from measurement data (e.g., Radon or Fourier transform data). However, these approaches are not sufficient for certain imaging techniques such as low-dose CT and fast MRI, or scenarios involving metal artifacts and patient motion. == Use in imaging modalities == === Computed tomography (CT) === In CT, deep learning models can be particularly effective in reducing radiation exposure while maintaining image quality. Deep neural networks can also be able to reconstruct images of fair quality from sparsely sampled data without sacrificing diagnostic performance. Deep learning-based generative AI models can reduce CT metal artifacts. === Magnetic resonance imaging (MRI) === In magnetic resonance imaging (MRI), deep learning can lead to reduced MRI motion artifacts, and increased acquisition speed, referred to as fast MRI. Despite suffering from disadvantages such as lower signal-to-noise ratio (SNR), deep learning can enhance image quality in low field MRI, making these systems clinically viable. === Positron emission tomography (PET) and single-photon emission CT (SPECT) === For PET imaging, deep learning models can provide substantial improvements in low-dose imaging and motion artifact correction. Also, deep learning can help SPECT for generation of attenuation background. A notable technique for PET denoising involves integrating MR data through multimodal networks, which use anatomical information from MRI to enhance PET image quality. === Ultrasound imaging === Deep learning can enhance ultrasound imaging by reducing speckle noise and motion blur. For ultrasound beamforming, deep neural networks can allow superior image quality with limited data at high speed. === Optical imaging and microscopy === Diffuse optical tomography, optical coherence tomography and microscopy can be improved by deep neural networks beyond traditional methods. Furthermore, deep learning can also enhance Photoacoustic imaging (see Deep learning in photoacoustic imaging), addressing challenges like high noise, low contrast, and limited resolution. Deep learning has also been applied to label-free live-cell imaging, where convolutional neural networks predict fluorescence labels from transmitted light images, a technique known as in silico labeling. This method can enable high-throughput, non-invasive cell analysis and phenotyping without the need for traditional fluorescent dyes.

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  • Cube 3D

    Cube 3D

    Cube 3D is an artificial intelligence model that is developed by Roblox Corporation. It is open source and available on GitHub and Hugging Face. In March 2026, Roblox announced Cube 3D as a mesh generation model that takes text input. In February 2026, Roblox released 4D creation in a public beta, allowing embedding Cube 3D into Roblox games. Cube 3D is integrated into Roblox Studio and its API, and supports two modes of 4D creation. == History == In March 2025, Roblox announced Cube 3D as a mesh generation model that takes text input. Its first feature was an API that allows mesh generation. That month, it was made open source. Over 1.8 million assets have been generated by Cube 3D since March 2025. In March 2025, 4D creation was announced. That November, 4D creation was released in early access. In February 2026, Roblox released 4D creation in a public beta, allowing embedding Cube 3D into Roblox games. == Technology == Cube 3D is trained on Roblox meshes. To generate meshes, it tokenises meshes and shapes and predicts the next token. Cube 3D is integrated into Roblox Studio and the Roblox Studio API. Its API allows mesh generation. In 4D creation, two modes can be used. Car-5 supports modular objects, and Body-1 only supports single-mesh objects.

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  • Smart speaker

    Smart speaker

    A smart speaker is a type of loudspeaker and voice command device with an integrated virtual assistant that offers interactive actions and hands-free activation with the help of one "wake word" (or several "wake words"). Some smart speakers also act as smart home hubs by using Wi-Fi, Bluetooth, Thread, and other protocol standards to extend usage beyond audio playback and control home automation devices connected through a local area network. == History == Early voice-activated devices began in 2013 with MIT's Jasper project, which used multiple microphones and cloud software to power hands-free interactions from across a room. The first commercial smart speaker was the Amazon Echo, which was released in 2014 powered by Alexa and a ring of far-field microphones. Google followed in 2016 with Home, powered by Google Assistant. By 2017, devices like the Echo Show and Home Hub (later called Nest Hub) added touchscreens and video, creating the "smart display" subcategory. In 2018, Apple joined the smart speaker trend by launching the HomePod, which focused on high-quality audio alongside their built-in assistant Siri. ASUS release its own smart Speaker Xiao-Bu in 2019 with Artificial Intelligence, it terminates the Cloud Service on June 1st, 2025, which means all real-time service such as weather, news, currency conversion is affected. Sonos's 1st smart speaker Sonos One released in 2017, powered by Alexa. Invoke by Harman Kardon was powered by Microsoft's intelligent personal assistant, Cortana. In the early 2020s, smart speakers gained on-device voice processing for faster responses and improved privacy. New standards such as Matter and Thread allowed multitudes of smart-home devices (even from completely different brands) to work together. == Features == === Audio and Voice === Smart speakers use multiple microphones along with noise-cancelling software to pick up your voice from across the room, even when music is playing or the assistant is already talking. Noise suppression and echo cancellation is also used by the speaker so it can focus in on who is talking and ignore any background noises. Most smart speaker models can recognize who is speaking by voiceprint, which allows the speaker to grab information from that person's calendar, preferences, or music playlists. Listening to music on a speaker is when importance for good audio quality becomes apparent. Entry-level (cheaper) speakers such as the Home Mini or the Echo Dot have a single full-range driver. These lower-end speakers typically aren't great for listening to music as the audio quality is pretty poor. More advanced units such as the Home Max or Echo Studio have separate tweeters and woofers meant for listening to music in high quality. === Connectivity and smart-home control === Most connect over Wi-Fi or Bluetooth and support hub protocols like Thread and Matter. That lets them not only stream and play music but also allows you to control various brands of smart lights, thermostats, door locks, cameras, and much more-all from one point of control. Each can have its own designated interface and features in-house, usually launched or controlled via application or home automation software. These devices are able to communicate with each other via peer-to-peer connection through mesh networking. These speakers and related smart devices are typically controlled with one smartphone application. === Assistant services and skills === The built-in assistants handle timers, alarms, reminders, news briefings, weather updates, send messages to other smart devices, send texts, make calls, and simple questions. You can combine actions together in what are typically known as routines (for example saying "good morning" turns on lights, starts the coffee, says the weather, and reads the news) and add extra functions known as skills or actions (for things like ordering food or playing trivia games). This hands-free use of smart speakers can help assist those with disabilities. Most other technologies need the user to be able to physically interact with the device. Smart speakers are not bound by these limitations and can serve as an excellent tool for those who are unable to use their arms or legs or have vision issues. Although these tasks can be completed by a phone or computer, consumers tend to lean towards smart speakers due to factors such as their range being much greater than that of a phone and the need to not have to physically interact with the speaker to get the voice assistant as with most smartphones, certain parts of a phone may need to be interacted with to activate the speaking assistant. === Smart displays === Some smart speakers also include a screen to show the user a visual response. A smart speaker with a touchscreen is known as a smart display; these integrate a conversational user interface with display screens to augment voice interaction with images and video. They are powered by one of the common voice assistants and offer additional controls for smart home devices, feature streaming apps, and web browsers with touch controls for selecting content. The first smart displays were introduced in 2017 by Amazon (Amazon Echo Show) and Google (Google/Nest Home Hub). Hotel chain Marriott International partnered with Amazon to install Echo devices in select hotels since 2018. A Taiwanese startup, Aiello, launched the Aiello Voice Assistant (AVA) in the Asian hotel market in 2019, claiming it is powered by a multi-AI model system. Angie by Nomadix, which is similar to the Amazon Echo, launched its first product in 2017, specifically targeting hotel properties in the North America. In May 2019, Angie Hospitality acquired the assets of Roxy, a competitor that also built its own speech-enabled virtual assistant technology for hotels. This acquisition merged two proprietary NLP stacks into the current Nomadix product. === Artificial intelligence === The newest speakers can use on-device AI or cloud-based generative models to allow the smart speaker to carry on much more natural conversations, draft emails or recipes, suggest ideas based on context, or even create short pieces of music or art. This AI evolution allows these speakers to do far more than what they could do before. == Accuracy == According to a study by Proceedings of the National Academy of Sciences of the United States of America released In March 2020, the six biggest tech development companies, Amazon, Apple, Google, Yandex, IBM and Microsoft, have misidentified more words spoken by "black people" than "white people". The systems tested errors and unreadability, with a 19 and 35 percent discrepancy for the former and a 2 and 20 percent discrepancy for the latter. The North American Chapter of the Association for Computational Linguistics (NAACL) also identified a discrepancy between male and female voices. According to their research, Google's speech recognition software is 13 percent more accurate for men than women. It performs better than the systems used by Bing, AT&T, and IBM. == Privacy concerns == The built-in microphone in smart speakers is continuously listening for wake words followed by a command. However, these continuously listening microphones also raise privacy concerns among users. According to a survey taken by 1,007 people in Western Europe, it is clear that privacy is the biggest concern holding consumers back from buying "smart" products. these concerns include what is being recorded, how the data will be used, how it will be protected, and whether it will be used for invasive advertising. Furthermore, an analysis of Amazon Echo Dots showed that 30–38% of "spurious audio recordings were human conversations", suggesting that these devices capture audio other than strictly detection of the wake word. === As a wiretap === There are strong concerns that the ever-listening microphone of smart speakers presents a perfect candidate for wiretapping. In 2017, British security researcher Mark Barnes showed that pre-2017 Echos have exposed pins which allow for a compromised OS to be booted. According to Umar Iqbal, an assistant professor at Washington University in St. Louis, research indicates that data from consumer interactions with Alexa was used to targeted advertisements and products to consumer with over 40% of transmitted data lacking proper encryption raising privacy concerns. Further data indicates that due to the Smart Speakers ability to always capture audio, it begins to pick up on external conversations from consumers not related to commands given to the smart speaker. Things such as other members in the household, consumers on the phone and even TV audio can be picked up by these speakers and stored for future use by companies. === Voice assistance vs privacy === While voice assistants provide a valuable service, there can be some hesitation towards using them in various social contexts, such as in public or around other users. However, only more recently have users begun interac

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  • Speech synthesis

    Speech synthesis

    Speech synthesis is the artificial production of human speech. A computer system used for this purpose is called a speech synthesizer, and can be implemented in software or hardware products. A text-to-speech (TTS) system converts normal language text into speech; other systems render symbolic linguistic representations like phonetic transcriptions into speech. The reverse process is speech recognition. Synthesized speech can be created by concatenating pieces of recorded speech that are stored in a database. Systems differ in the size of the stored speech units; a system that stores phones or diphones provides the largest output range, but may lack clarity. For specific usage domains, the storage of entire words or sentences allows for high-quality output. Alternatively, a synthesizer can incorporate a model of the vocal tract and other human voice characteristics to create a completely "synthetic" voice output. The quality of a speech synthesizer is judged by its similarity to the human voice and by its ability to be understood clearly. An intelligible text-to-speech program allows people with visual impairments or reading disabilities to listen to written words on a home computer. The earliest computer operating system to have included a speech synthesizer was Unix in 1974, through the Unix speak utility. In 2000, Microsoft Sam was the default text-to-speech voice synthesizer used by the narrator accessibility feature, which shipped with all Windows 2000 operating systems, and subsequent Windows XP systems. A text-to-speech system (or "engine") is composed of two parts: a front-end and a back-end. The front-end has two major tasks. First, it converts raw text containing symbols like numbers and abbreviations into the equivalent of written-out words. This process is often called text normalization, pre-processing, or tokenization. The front-end then assigns phonetic transcriptions to each word, and divides and marks the text into prosodic units, like phrases, clauses, and sentences. The process of assigning phonetic transcriptions to words is called text-to-phoneme or grapheme-to-phoneme conversion. Phonetic transcriptions and prosody information together make up the symbolic linguistic representation that is output by the front-end. The back-end—often referred to as the synthesizer—then converts the symbolic linguistic representation into sound. In certain systems, this part includes the computation of the target prosody (pitch contour, phoneme durations), which is then imposed on the output speech. == History == Long before the invention of electronic signal processing, some people tried to build machines to emulate human speech. There were also legends of the existence of "Brazen Heads", such as those involving Pope Silvester II (d. 1003 AD), Albertus Magnus (1198–1280), and Roger Bacon (1214–1294). In 1779, the German-Danish scientist Christian Gottlieb Kratzenstein won the first prize in a competition announced by the Russian Imperial Academy of Sciences and Arts for models he built of the human vocal tract that could produce the five long vowel sounds (in International Phonetic Alphabet notation: [aː], [eː], [iː], [oː] and [uː]). There followed the bellows-operated "acoustic-mechanical speech machine" of Wolfgang von Kempelen of Pressburg, Hungary, described in a 1791 paper. This machine added models of the tongue and lips, enabling it to produce consonants as well as vowels. In 1837, Charles Wheatstone produced a "speaking machine" based on von Kempelen's design, and in 1846, Joseph Faber exhibited the "Euphonia". In 1923, Paget resurrected Wheatstone's design. In the 1930s, Bell Labs developed the vocoder, which automatically analyzed speech into its fundamental tones and resonances. From his work on the vocoder, Homer Dudley developed a keyboard-operated voice-synthesizer called The Voder (Voice Demonstrator), which he exhibited at the 1939 New York World's Fair. Franklin S. Cooper and his colleagues at Haskins Laboratories built the pattern playback in the late 1940s and completed it in 1950. There were several different versions of this hardware device; only one currently survives. The machine converts pictures of the acoustic patterns of speech in the form of a spectrogram back into sound. Using this device, Alvin Liberman and colleagues discovered acoustic cues for the perception of phonetic segments (consonants and vowels). === Electronic devices === The first computer-based speech-synthesis systems originated in the late 1950s. Noriko Umeda et al. developed the first general English text-to-speech system in 1968, at the Electrotechnical Laboratory in Japan. In 1961, physicist John Larry Kelly, Jr and his colleague Louis Gerstman used an IBM 704 computer to synthesize speech, an event among the most prominent in the history of Bell Labs. Kelly's voice recorder synthesizer (vocoder) recreated the song "Daisy Bell", with musical accompaniment from Max Mathews. Coincidentally, Arthur C. Clarke was visiting his friend and colleague John Pierce at the Bell Labs Murray Hill facility. Clarke was so impressed by the demonstration that he used it in the climactic scene of his screenplay for his novel 2001: A Space Odyssey, where the HAL 9000 computer sings the same song as astronaut Dave Bowman puts it to sleep. Despite the success of purely electronic speech synthesis, research into mechanical speech-synthesizers continues. Linear predictive coding (LPC), a form of speech coding, began development with the work of Fumitada Itakura of Nagoya University and Shuzo Saito of Nippon Telegraph and Telephone (NTT) in 1966. Further developments in LPC technology were made by Bishnu S. Atal and Manfred R. Schroeder at Bell Labs during the 1970s. LPC was later the basis for early speech synthesizer chips, such as the Texas Instruments LPC Speech Chips used in the Speak & Spell toys from 1978. In 1975, Fumitada Itakura developed the line spectral pairs (LSP) method for high-compression speech coding, while at NTT. From 1975 to 1981, Itakura studied problems in speech analysis and synthesis based on the LSP method. In 1980, his team developed an LSP-based speech synthesizer chip. LSP is an important technology for speech synthesis and coding, and in the 1990s was adopted by almost all international speech coding standards as an essential component, contributing to the enhancement of digital speech communication over mobile channels and the internet. In 1975, MUSA was released, and was one of the first Speech Synthesis systems. It consisted of a stand-alone computer hardware and a specialized software that enabled it to read Italian. A second version, released in 1978, was also able to sing Italian in an "a cappella" style. Dominant systems in the 1980s and 1990s were the DECtalk system, based largely on the work of Dennis Klatt at MIT, and the Bell Labs system; the latter was one of the first multilingual language-independent systems, making extensive use of natural language processing methods. Handheld electronics featuring speech synthesis began emerging in the 1970s. One of the first was the Telesensory Systems Inc. (TSI) Speech+ portable calculator for the blind in 1976. Other devices had primarily educational purposes, such as the Speak & Spell toy produced by Texas Instruments in 1978. Fidelity released a speaking version of its electronic chess computer in 1979. The first video game to feature speech synthesis was the 1980 shoot 'em up arcade game, Stratovox (known in Japan as Speak & Rescue), from Sun Electronics. The first personal computer game with speech synthesis was Manbiki Shoujo (Shoplifting Girl), released in 1980 for the PET 2001, for which the game's developer, Hiroshi Suzuki, developed a "zero cross" programming technique to produce a synthesized speech waveform. Another early example, the arcade version of Berzerk, also dates from 1980. The Milton Bradley Company produced the first multi-player electronic game using voice synthesis, Milton, in the same year. In 1976, Computalker Consultants released their CT-1 Speech Synthesizer. Designed by D. Lloyd Rice and Jim Cooper, it was an analog synthesizer built to work with microcomputers using the S-100 bus standard. Synthesized voices typically sounded male until 1990, when Ann Syrdal, at AT&T Bell Laboratories, created a female voice. Ray Kurzweil predicted in 2005 that as the cost-performance ratio caused speech synthesizers to become cheaper and more accessible, more people would benefit from the use of text-to-speech programs. === Artificial intelligence === In September 2016, DeepMind released WaveNet, which demonstrated that deep learning models are capable of modeling raw waveforms and generating speech from acoustic features like spectrograms or mel-spectrograms, starting the field of deep learning speech synthesis. Although WaveNet was initially considered to be computationally expensive and slow to be used in consumer products at the time, a year after its

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  • List of Ada software and tools

    List of Ada software and tools

    This is a list of software and programming tools for the Ada programming language, including IDEs, compilers, libraries, verification and debugging tools, numerical and scientific computing libraries, and related projects. == Compilers == GNAT — GCC Ada compiler and toolchain, maintained by AdaCore AdaCore GNAT Pro — commercial Ada compiler with advanced tooling for high-integrity and real-time systems Green Hills compiler for Ada — Ada compiler for embedded and safety-critical systems ObjectAda — Ada development environment for safety-critical and embedded systems == Integrated development environments (IDEs) and editors == GNAT Studio — IDE developed by AdaCore Emacs — supports Ada editing with Ada mode and syntax checking Eclipse — supports Ada through GNATbench plugin Visual Studio Code — Ada support via Ada Language Server extensions == Libraries and frameworks == See also: Ada Libraries on Wikibooks Ada.Calendar — date and time library Ada Web Services (AWS) — support for RESTful and SOAP web services Ada.Text_IO — standard library for text input/output Florist (POSIX Ada binding) – open-source implementation of the POSIX Ada bindings GNAT – Ada compiler part of GCC, which also provides an extensive runtime and library package hierarchy. GtkAda – Ada bindings for the GTK+ graphical user interface toolkit Matreshka – multipurpose Ada framework supporting Unicode, XML, JSON, and more. XML/Ada – XML and Unicode processing library == Real-time and embedded systems == Ada tasking — built-in concurrency support with tasks, protected objects, and rendezvous. Ada.Real_Time — real-time clocks, delays, and scheduling. ARINC 653 Ada profiles — for avionics real-time applications OpenMP Ada bindings — parallel programming for multi-core embedded systems Ravenscar profile — subset of Ada tasking for real-time and deterministic execution == Numerical and scientific computing == Ada.Numerics — libraries for numerical methods, linear algebra, and mathematical functions. SPARK math libraries — formal-methods-compliant numerical routines == Verification, debugging, and analysis == GNATprove — formal verification and static analysis tool for Ada and SPARK GNATstack — runtime stack analysis and checking GNATcoverage — code coverage measurement for Ada projects AdaControl — style checking and metrics for Ada == Testing frameworks == AUnit — unit testing framework for Ada GNATtest — automated testing framework for Ada == Documentation and code generation == GNATdoc — generates HTML documentation from Ada source code

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  • Futuresport

    Futuresport

    Futuresport is a 1998 American made-for-television sports film directed by Ernest Dickerson, starring Dean Cain, Vanessa Williams, and Wesley Snipes. It originally aired on ABC in October 1998, was released on VHS and DVD in March 1999 and then distributed outside of the U.S. by Minerva Pictures. == Plot == The film is set in 2025, and centers on a sport called "Futuresport" (a combination of basketball, baseball and hockey that uses hoverboards and rollerblades) created as a non-lethal way to reduce gang warfare. Tre Ramzey (Dean Cain) along with his ex-girlfriend Alex Torres (Vanessa Williams) and his old coach Obike Fixx (Wesley Snipes) must prevent an all out war between the North American Alliance and the Pan-Pacific Commonwealth (The Com). At stake is who rules over the Hawaiian Islands—which are being terrorized by Eric Sythe (JR Bourne) and his gang the Hawaiian Liberation Organization (Hilo). It takes a revolutionary sport to stop a revolution. == Cast ==

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  • SciGraph

    SciGraph

    SciGraph was a search engine tool developed by Springer Nature, the former URL was https://scigraph.springernature.com/explorer. The technology, which was considered a Linked Open Data (LOD) platform, collects information that covers the research landscape, which includes research projects, publications, conferences, funding agencies, and others. Key features of the platform include the detailed semantic description of the relationship of information and the visualization of the scholarly domain. It was launched in 2017 and retired in 2023. == Development == The development of SciGraph began with an initiative to create a platform that will host Springer Nature's entire publication archive, which cover texts published as early as 1815. The number of these resources is reported to be about 13 million. The technology behind the platform was built on earlier Springer Nature projects developed for the purpose of collecting information on the research landscape. The first SciGraph data set was published in February 2017. The platform was launched in March 2017 and significantly expanded with the addition of publications of key partners. The datasets span a broad range of topics, which include computer science, medicine, life sciences, chemistry, engineering, and astronomy, among others. The developers also plan to include citations, patents, and clinical trials in the future. == Technology == SciGraph constitutes 1.5 to 2 billion triples where a triple is formatted as "subject-predicate-object" and could link any subject or concept through a predicate (verb) to another object, demonstrating the type of relationship that exists between them. Its graph structure is used by other academic search engines such as Semantic Scholar. SciGraph collects data from Springer Nature and its partners from the scholarly domain as well as funders, research projects, conferences, affiliations, and publications. The collected information serves as rich semantic description of how information is related and it also provides a visualization of the scholarly domain. The platform has been considered the only large-scale dataset that reconciles authors' affiliations through the disambiguation and linking with external authoritative datasets according to institutions.

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  • Resistance Database Initiative

    Resistance Database Initiative

    HIV Resistance Response Database Initiative (RDI) was formed in 2002 to use artificial intelligence (AI) to predict how patients will respond to HIV drugs using data from more 250,000 patients from around 50 countries around the world. The RDI used its models to power its HIV Treatment Response Prediction System (HIV-TRePS). Launched in 2010, this free online tool enabled healthcare professionals to upload their patient’s data and obtain highly accurate predictions of how they would respond to different combinations of the 30 or more drugs available. The tool enabled physicians to individualize their patients’ treatment, using these predictions based on more than a million patient-years of treatment experience. HIV-TRePS was possibly the first ever AI-based system for medical decision-making to be developed, successfully tested, and used in clinical practice. It has since been used by thousands of healthcare professionals to optimise the treatment of tens of thousands of patients. Since the RDI’s inception the treatment of HIV infection has progressed enormously, with more effective and better tolerated drugs available in ever more convenient combination formulations. In most countries HIV is now considered a chronic, manageable condition. Moreover, the success of the drugs in reducing the amount of virus is substantially reducing the onward transmission of the virus and cases of new infections are falling in many settings. This improvement in HIV treatment means the need for sophisticated AI to support HIV treatment decisions has significantly reduced. In response, the RDI ceased development of further models and, in March 2024, withdrew its HIV-TRePS system. == Background == Human immunodeficiency virus (HIV) is the virus that causes acquired immunodeficiency syndrome (AIDS), a condition in which the immune system begins to fail, leading to life-threatening opportunistic infections. There are approximately 30 HIV antiretroviral drugs that have been approved for the treatment of HIV infection, from six different classes, based on the point in the HIV life-cycle at which they act. They are used in combination; typically 3 or more drugs from 2 or more different classes, a form of therapy known as highly active antiretroviral therapy (HAART). The aim of therapy is to suppress the virus to very low, ideally undetectable, levels in the blood. This prevents the virus from depleting the immune cells that it preferentially attacks CD4 cells and prevents or delays illness and death. Despite the expanding availability of these drugs and the impact of their use, treatments continue to fail, often involving to the development of resistance. During drug therapy, low-level virus replication may still occur, particularly when a patient misses a dose. HIV makes errors in copying its genetic material and, if a mutation makes the virus resistant to one or more of the drugs in the patient's treatment, it may begin to replicate more successfully in the presence of that drug and undermine the effect of the treatment. If this happens, the treatment needs to be changed to re-establish control over the virus. == RDI's Approach == The RDI’s approach was to use artificial intelligence (including neural network and random forest models), trained with data from hundreds of thousands of patients, treated with different drugs in a variety of clinical settings all over the world, to predict how an individual patient will respond to any new combination of HIV drugs. The models were tested with independent data sets and consistently achieved accuracy of approximately 80%.

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  • CloudSim

    CloudSim

    CloudSim is a framework for modeling and simulation of cloud computing infrastructures and services. Originally built primarily at the Cloud Computing and Distributed Systems (CLOUDS) Laboratory, the University of Melbourne, Australia, CloudSim has become one of the most popular open source cloud simulators in the research and academia. CloudSim is completely written in Java. The latest version of CloudSim is CloudSim v6.0.0-beta on GitHub. Cloudsim is suitable for implementing simulations scenarios based on Infrastructure as a service as well as with latest version Platform as a service, so get started here == CloudSim extensions == Initially developed as a stand-alone cloud simulator, CloudSim has further been extended by independent researchers. GPUCloudSim is an enhanced CloudSim tool for modeling GPU-based cloud infrastructures and data centers. It offers simulations for multi-GPU setups, customizable GPU policies, GPU remoting, etc. It also examines performance impacts and interactions within virtualized GPU environments. CloudSim Plus is a totally re-engineered CloudSim fork providing general-purpose cloud computing simulation and exclusive features such as: multi-cloud simulations, vertical and horizontal VM scaling, host fault injection and recovery, joint power- and network-aware simulations and more. Though CloudSim itself does not have a graphical user interface, extensions such as CloudReports offer a GUI for CloudSim simulations. CloudSimEx extends CloudSim by adding MapReduce simulation capabilities and parallel simulations. Cloud2Sim extends CloudSim to execute on multiple distributed servers, by leveraging Hazelcast distributed execution framework. RECAP DES extends the CloudSim Plus framework to model synchronous hierarchical architectures (such as ElasticSearch). ThermoSim extends CloudSim toolkit by incorporating thermal characteristics, and uses Deep learning-based temperature predictor for cloud nodes.

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  • Tamarin Prover

    Tamarin Prover

    Tamarin Prover is a computer software program for formal verification of cryptographic protocols. It has been used to verify Transport Layer Security 1.3, ISO/IEC 9798, DNP3 Secure Authentication v5, WireGuard, and the PQ3 Messaging Protocol of Apple iMessage. Tamarin is an open source tool, written in Haskell, built as a successor to an older verification tool called Scyther. Tamarin has automatic proof features, but can also be self-guided. In Tamarin lemmas that representing security properties are defined. After changes are made to a protocol, Tamarin can verify if the security properties are maintained. The results of a Tamarin execution will either be a proof that the security property holds within the protocol, an example protocol run where the security property does not hold, or Tamarin could potentially fail to halt.

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  • Overwatch

    Overwatch

    Overwatch (abbreviated as OW) is a multimedia franchise centered on a series of multiplayer first-person shooter (FPS) video games developed by Blizzard Entertainment. Overwatch was released in 2016. Overwatch 2 was released in 2022 and the original game was taken offline upon its release, though Blizzard renamed it back to Overwatch in 2026. Overwatch features hero-based combat between two teams of players fighting over various objectives, along with other traditional gameplay modes. Released in 2016, Overwatch lacked a traditional story mode. Instead, Blizzard employed a transmedia storytelling strategy to disseminate lore regarding the game's characters, releasing comics and other literary media, as well as animated media that includes short films. The game enjoyed both critical and commercial success, and garnered a devoted following. The fan community around the franchise has produced a large amount of content including art, cosplay, fan fiction, anime-influenced music videos, Internet memes, and pornography. Blizzard helped launch and promote an esports scene surrounding the game, including an annual Overwatch World Cup, Overwatch League a minor league, and the Overwatch Champions Series which borrowed elements found in traditional American sports leagues. == Gameplay == Both games in the Overwatch series are team-based hero shooters. Players select a hero character from a large roster (52 as of Season 2), divided among three class types. These are: Tanks, who have higher health and generally meant to help protect their teammates from damage, but are larger and easier to hit; Damage, who act as the team's offensive leads; and Support, who heal, provide buffs for teammates, or de-buff the opposing team. Each role also features sub-roles with extra passives. These sub-roles include 'Initiator', 'Stalwart', and 'Bruiser' for Tank. 'Specialist', 'Flanker', 'Recon', and 'Sharpshooter' for Damage. 'Medic', 'Tactician', and 'Survivor' for Support. Players are generally free to change to different heroes while inside their spawn room during the course of a match in response to the current tactics employed by other players. As of the development of Overwatch 2, a standard game features one tank player, two damage players and two support players, a change from having two of each class in its predecessor. Players choose their class before the match, and can only pick characters within that class for the duration of the game. There are different styles of game modes, however, that allow players to choose characters from any class throughout the game. Each hero has a skill kit that includes a primary attack, active skills that require a cooldown period before they can be used again, passive skills that remain active at all times, and an Ultimate skill that can only be used once they fill their Ultimate meter either by damaging opponents, mitigating damage, healing teammates or by passively generating it over time. An update in 2025 saw each hero receive a total of four unique abilities known as perks. Each hero has two minor and two major perks; minor perks consist of smaller changes to a hero's kit, while major perks are intended to affect the match more significantly. At the beginning of each match, all heroes are set to level 1 for each player. As the match progresses, players can individually level up their respective heroes, minor perks are unlocked at level 2, and major perks are unlocked at the maximum level 3. When perks become available, players may only select one of each type of perk; a selected perk becomes irreversibly attached to the current hero for the remainder of the match. If a player switches to another hero mid-match, the previously selected hero retains their level and perk progress. Game types of Overwatch are split between standard matches, competitive play, custom games, and arcade modes. Standard matches have matchmaking based loosely on the player's skill level as measured by the game. Competitive mode uses more strict matchmaking based on a player's current rank on the competitive ladder, with their rank increasing or decreasing when they win or lose a game, respectively. Arcade modes do not use matchmaking and are generally more experimental modes compared to standard and competitive modes. Custom games are created via the workshop and can be utilised to make game modes that are very different from the base game. The workshop, is the software in Overwatch which creates the game using either presets and settings or rules and conditions made by code. These game modes can be published directly onto Overwatch’s custom browse tab or shared off platform using a 5 digit alphanumeric code. Standard and competitive game modes are randomly selected at the start of each match, and are objective based, requiring teams to control a fixed objective point for a duration of time, or escort a payload to a target zone before match time expires. These modes include: Assault (introduced in Overwatch): Also known as 2 Capture Points (or 2CP), Assault has the attacking team tasked with capturing two target points in sequence on the map, while the defending team must stop them. Assault-style maps were removed from main gameplay rotation after Overwatch 2 released but available in the game's arcade mode. It is still available in the game's custom game modes. Since Season 2, Assault-style maps are available in Arcade Mode daily routines. Escort (introduced in Overwatch): Also known as "Payload" by the community, The attacking team is tasked with escorting a payload to a certain delivery point before time runs out, while the defending team must stop them. The payload vehicle moves along a fixed track when any player on the attacking team is close to it, increasing in speed if multiple attackers are present, the increase capping at 3, but will stop if a defending player is nearby; should no attacker be near the vehicle, it will start to move backwards along the track. The payload will also heal any attacking players by 10 health per second while they are near the payload. Passing specific checkpoints will extend the match time and prevent the payload from moving backwards from that point. Hybrid (Assault/Escort) (introduced in Overwatch): The attacking team has to capture the payload (as if it were a target point from Assault) and escort it to its destination, while the defending team tries to hold them back. Control (introduced in Overwatch): Each team tries to capture and maintain a common control point until their capture percentage reaches 100%. This game mode is played in a best-of-three format. Control maps are laid out in a symmetric fashion so no team has an intrinsic position advantage. Push (introduced in Overwatch 2's launch): Each team attempts to secure control of a large robot that pushes one of two barriers to the opposing team's side of the map, whilst being escorted by at least one team member, stopping when enemy players are nearby, similar to the payload movement system in Escort. The team that pushes the payload fully to the other side, or furthest into the enemy territory before the time runs out, wins the match. Flashpoint (introduced in Overwatch 2 in 2023): Similar to Control, each team attempts to capture and maintain a common control point until their capture percentage reaches 100%. This game mode takes place on significantly larger maps with five separate control points, which take a shorter amount of time to capture as compared to a standard Control map. A central control point is always activated first; after it is secured by one team, the remaining four are activated in a random order. The first team to secure three control points wins. Clash (introduced in Overwatch 2 in 2024): Clash maps feature symmetrical maps with five control points. Teams initially vie for control of the central point, with the winning team progressing to the next control point, towards the opponent's base. Opponents can push back by winning control points and shifting the next point away from their base. If a team captures the point closest to the opponent's base, they win. Otherwise the match plays out until one team wins control five times. Arcade modes may include variations of the above modes with experimental rules, and can also include modes like Deathmatch and Capture the Flag. Other common arcade modes include: Elimination (introduced in Overwatch in 2016): Two teams face off in a series of rounds, attempting to wipe out the other team; once a player is killed they remain out of the game until the next round, though they can be revived by Mercy's 'Resurrect' ability. If no team has won a round by a certain time, then the winners are decided by the team that can first take a neutral control point. Players cannot change heroes until the next round. Some of these can be played in "lockout" mode, in which the heroes selected by the winning team for a round are "locked" and cannot be selected in future rounds. Total Mayhem (i

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  • Project Debater

    Project Debater

    Project Debater is an IBM artificial intelligence project, designed to participate in a full live debate with expert human debaters. It follows on from the Watson project which played Jeopardy! == Development == Project Debater was developed at IBM's lab in Haifa, Israel. The project was proposed by Noam Slonim in 2011 as the IBM Research next Grand Challenge, following Deep Blue and the victory of Watson in Jeopardy! It was exposed for the first time in a closed media event at June 18, 2018, in San Francisco, under the leadership of Ranit Aharonov and Slonim, both from the IBM Research lab in Haifa, Israel. The AI technology debated two human debaters, Noa Ovadia, who was the 2016 Israeli debate champion and Dan Zafrir. The two debated on the topics "We should subsidize space exploration" and "Should we increase the use of telemedicine." A demonstration of Project Debater also aired on the Discovery Channel in June 2018 debating the question of whether sports gambling should be legalized. == Live Debate == On February 11, 2019, Project Debater was revealed to the world in a live debate in San Francisco. Nonpartisan media group Intelligence Squared U.S. Debates hosted the debate which was moderated by journalist John Donvan. The debate took place between Project Debater and Harish Natarajan, who holds the world record in number of debate competition victories. The motion was “We should subsidize preschools.” == That's Debatable Television Show == Project Debater was featured in a television series called “That’s Debatable” presented by Intelligence Squared U.S. Debates and Bloomberg Media. For each episode of “That’s Debatable,” Project Debater provided insight into three distinct debate topics on the redistribution of wealth, modern monetary theory, and a US-China space race. More than 5,000 arguments were submitted online from around the world across the three topics, which were then analyzed and distilled into key points that were highlighted on the television show and discussed by human debaters. == Artificial Intelligence Capabilities == To develop Project Debater, the IBM Research team had to endow the system with the following AI capabilities: Data-driven speech writing and delivery: Project Debater is the first demonstration of a computer that can digest massive corpora, and given a short description of a controversial topic, write a well-structured speech, and deliver it with clarity and purpose, while even incorporating humor where appropriate. Listening comprehension: the ability to identify the key concepts and claims hidden within long continuous spoken language. Four minutes of persuasive speech: the guarantee of producing four minutes of persuasive speech. Modeling human dilemmas: modeling the world of human controversy and dilemmas in a unique knowledge representation, enabling the system to suggest principled arguments as needed. An article on the project was published in Nature in March 2021.

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  • Traceability

    Traceability

    Traceability is the capability to trace something. In some cases, it is interpreted as the ability to verify the history, location, or application of an item by means of documented recorded identification. Other common definitions include the capability (and implementation) of keeping track of a given set or type of information to a given degree, or the ability to chronologically interrelate uniquely identifiable entities in a way that is verifiable. Traceability is applicable to measurement, supply chain, software development, healthcare and security. == Measurement == The term measurement traceability or metrological traceability is used to refer to an unbroken chain of comparisons relating an instrument's measurements to a known standard. Calibration to a traceable standard can be used to determine an instrument's bias, precision, and accuracy. It may also be used to show a chain of custody—from current interpretation of evidence to the actual evidence in a legal context, or history of handling of any information. In many countries, national standards for weights and measures are maintained by a National Metrological Institute (NMI) which provides the highest level of standards for the calibration / measurement traceability infrastructure in that country. Examples of government agencies include the National Physical Laboratory, UK (NPL) the National Institute of Standards and Technology (NIST) in the USA, the Physikalisch-Technische Bundesanstalt (PTB) in Germany, the Instituto Nazionale di Ricerca Metrologica (INRiM) in Italy, and the National Research Council of Canada (NRC). As defined by NIST, "Traceability of measurement requires the establishment of an unbroken chain of comparisons to stated references each with a stated uncertainty." A clock providing traceable time is traceable to a time standard such as Coordinated Universal Time or International Atomic Time. The Global Positioning System is a source of traceable time. === Food processing === In food processing (meat processing, fresh produce processing), the term traceability refers to the recording through means of barcodes or RFID tags and other tracking media, all movement of product and steps within the production process. One of the key reasons this is such a critical point is in instances where an issue of contamination arises, and a recall is required. Where traceability has been closely adhered to, it is possible to identify, by precise date/time and exact location which goods must be recalled, and which are safe, potentially saving millions of dollars in the recall process. Traceability within the food processing industry is also utilised to identify key high production and quality areas of a business, versus those of low return, and where points in the production process may be improved. In food processing software, traceability systems imply the use of a unique piece of data (e.g., order date/time or a serialized sequence number, generally through the use of a barcode / RFID) which can be traced through the entire production flow, linking all sections of the business, including suppliers and future sales through the supply chain. Messages and files at any point in the system can then be audited for correctness and completeness, using the traceability software to find the particular transaction and/or product within the supply chain. In food systems, ISO 22005, as part of the ISO 22000 family of standards, has been developed to define the principles for food traceability and specifies the basic requirements for the design and implementation of a feed and food traceability system. It can be applied by an organization operating at any step in the feed and food chain. The European Union's General Food Law came into force in 2002, making traceability compulsory for food and feed operators and requiring those businesses to implement traceability systems. The EU introduced its Trade Control and Expert System, or TRACES, in April 2004. The system provides a central database to track movement of animals within the EU and from third countries. Australia has its National Livestock Identification System to keep track of livestock from birth to slaughterhouse. India has started taking initiatives for setting up traceability systems at Government and Corporate levels. Grapenet, an initiative by Agriculture and Processed Food Products Export Development Authority (APEDA), Ministry of Commerce, Government of India is an example in this direction. GrapeNet is an internet based traceability software system for monitoring fresh grapes exported from India to the European Union. GrapeNet is a first of its kind initiative in India that has put in place an end-to-end system for monitoring pesticide residue, achieve product standardization and facilitate tracing back from pallets to the farm of the Indian grower, through the various stages of sampling, testing, certification and packing. Grapenet won the National Award (Gold), in the winners announced for the best e-Governance initiatives undertaken in India in 2007. The Directorate Generate Foreign Trade (DGFT), Government of India, through its notification dated 04.02.2009 relating to Amendment in Foreign Trade Policy (RE2008)has mandated that Export to the European Union is permitted subject to registration with APEDA, thereby making Grapenet mandatory for all exports of fresh grapes from India to Europe. Uruguay has also designed a system called "Traceability & Electronic Information System of the Beef Industry". Traceability in food supply can also refer to practices employed by individual companies, including Ritual and Amway's Nutrilite. In the case of Nutrilite's supplements, ingredients are documented and tested throughout farming, processing, and manufacturing to ensure traceability at each stage of production. == Systems and software development == In systems and software development, the term traceability (or requirements traceability) refers to the ability to link product requirements back to stakeholders' rationales and forward to corresponding design artifacts, code, and test cases. Traceability supports numerous software engineering activities such as change impact analysis, compliance verification or traceback of code, regression test selection, and requirements validation. It is usually accomplished in the form of a matrix created for the verification and validation of the project. Unfortunately, the practice of constructing and maintaining a requirements trace matrix (RTM) can be very arduous and over time the traces tend to erode into an inaccurate state unless date/time stamped. Alternate automated approaches for generating traces using information retrieval methods have been developed. The IEEE defines traceability as "(1)The degree to which a relationship can be established between two or more products of the development process, especially products having a predecessor, successor or master-subordinate relationship to one another. For example, the degree to which the requirements and design of a given software component match. See also: consistency. " and "(2) The degree to which each element in a software development product establishes its reason for existing; for example, the degree to which each element in a bubble chart references the requirement that it satisfies." In transaction processing software, traceability implies use of a unique piece of data (e.g., order date/time or a serialized sequence number) which can be traced through the entire software flow of all relevant application programs. Messages and files at any point in the system can then be audited for correctness and completeness, using the traceability key to find the particular transaction. This is also sometimes referred to as the transaction footprint. == Health care == Patient safety during healthcare service plays an important role in preventing delayed recovery or even mortality, by increasing and improving the quality of life of citizens, and is considered an indicator of the quality status of health services Maintaining patient safety is a complex task and involves factors inherent to the environment and human actions. New technologies facilitate the traceability tools of patients and medications. This is particularly relevant for drugs that are considered high risk and cost. Recent research in the healthcare industry emphasizes the significant impact of Blockchain Technology (BCT) on improving the performance of healthcare supply chain management. It highlights BCT's role in enhancing transparency, data immutability, and efficient management, leading to better cooperation among stakeholders and effective risk mitigation in healthcare services. The World Health Organization has recognized the importance of traceability for medical products of human origin (MPHO) and urged member states "to encourage the implementation of globally consistent coding systems to facilitate national and international traceability". == Security and cri

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  • Resistance Database Initiative

    Resistance Database Initiative

    HIV Resistance Response Database Initiative (RDI) was formed in 2002 to use artificial intelligence (AI) to predict how patients will respond to HIV drugs using data from more 250,000 patients from around 50 countries around the world. The RDI used its models to power its HIV Treatment Response Prediction System (HIV-TRePS). Launched in 2010, this free online tool enabled healthcare professionals to upload their patient’s data and obtain highly accurate predictions of how they would respond to different combinations of the 30 or more drugs available. The tool enabled physicians to individualize their patients’ treatment, using these predictions based on more than a million patient-years of treatment experience. HIV-TRePS was possibly the first ever AI-based system for medical decision-making to be developed, successfully tested, and used in clinical practice. It has since been used by thousands of healthcare professionals to optimise the treatment of tens of thousands of patients. Since the RDI’s inception the treatment of HIV infection has progressed enormously, with more effective and better tolerated drugs available in ever more convenient combination formulations. In most countries HIV is now considered a chronic, manageable condition. Moreover, the success of the drugs in reducing the amount of virus is substantially reducing the onward transmission of the virus and cases of new infections are falling in many settings. This improvement in HIV treatment means the need for sophisticated AI to support HIV treatment decisions has significantly reduced. In response, the RDI ceased development of further models and, in March 2024, withdrew its HIV-TRePS system. == Background == Human immunodeficiency virus (HIV) is the virus that causes acquired immunodeficiency syndrome (AIDS), a condition in which the immune system begins to fail, leading to life-threatening opportunistic infections. There are approximately 30 HIV antiretroviral drugs that have been approved for the treatment of HIV infection, from six different classes, based on the point in the HIV life-cycle at which they act. They are used in combination; typically 3 or more drugs from 2 or more different classes, a form of therapy known as highly active antiretroviral therapy (HAART). The aim of therapy is to suppress the virus to very low, ideally undetectable, levels in the blood. This prevents the virus from depleting the immune cells that it preferentially attacks CD4 cells and prevents or delays illness and death. Despite the expanding availability of these drugs and the impact of their use, treatments continue to fail, often involving to the development of resistance. During drug therapy, low-level virus replication may still occur, particularly when a patient misses a dose. HIV makes errors in copying its genetic material and, if a mutation makes the virus resistant to one or more of the drugs in the patient's treatment, it may begin to replicate more successfully in the presence of that drug and undermine the effect of the treatment. If this happens, the treatment needs to be changed to re-establish control over the virus. == RDI's Approach == The RDI’s approach was to use artificial intelligence (including neural network and random forest models), trained with data from hundreds of thousands of patients, treated with different drugs in a variety of clinical settings all over the world, to predict how an individual patient will respond to any new combination of HIV drugs. The models were tested with independent data sets and consistently achieved accuracy of approximately 80%.

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  • Blackboard system

    Blackboard system

    A blackboard system is an artificial intelligence approach based on the blackboard architectural model, where a common knowledge base, the "blackboard", is iteratively updated by a diverse group of specialist knowledge sources, starting with a problem specification and ending with a solution. Each knowledge source updates the blackboard with a partial solution when its internal constraints match the blackboard state. In this way, the specialists work together to solve the problem. The blackboard model was originally designed as a way to handle complex, ill-defined problems, where the solution is the sum of its parts. == Metaphor == The following scenario provides a simple metaphor that gives some insight into how a blackboard functions: A group of specialists are seated in a room with a large blackboard. They work as a team to brainstorm a solution to a problem, using the blackboard as the workplace for cooperatively developing the solution. The session begins when the problem specifications are written onto the blackboard. The specialists all watch the blackboard, looking for an opportunity to apply their expertise to the developing solution. When someone writes something on the blackboard that allows another specialist to apply their expertise, the second specialist records their contribution on the blackboard, hopefully enabling other specialists to then apply their expertise. This process of adding contributions to the blackboard continues until the problem has been solved. == Components == A blackboard-system application consists of three major components The software specialist modules, which are called knowledge sources (KSs). Like the human experts at a blackboard, each knowledge source provides specific expertise needed by the application. The blackboard, a shared repository of problems, partial solutions, suggestions, and contributed information. The blackboard can be thought of as a dynamic "library" of contributions to the current problem that have been recently "published" by other knowledge sources. The control shell, which controls the flow of problem-solving activity in the system. Just as the eager human specialists need a moderator to prevent them from trampling each other in a mad dash to grab the chalk, KSs need a mechanism to organize their use in the most effective and coherent fashion. In a blackboard system, this is provided by the control shell. === Learnable Task Modeling Language === A blackboard system is the central space in a multi-agent system. It's used for describing the world as a communication platform for agents. To realize a blackboard in a computer program, a machine readable notation is needed in which facts can be stored. One attempt in doing so is a SQL database, another option is the Learnable Task Modeling Language (LTML). The syntax of the LTML planning language is similar to PDDL, but adds extra features like control structures and OWL-S models. LTML was developed in 2007 as part of a much larger project called POIROT (Plan Order Induction by Reasoning from One Trial), which is a Learning from demonstrations framework for process mining. In POIROT, Plan traces and hypotheses are stored in the LTML syntax for creating semantic web services. Here is a small example: A human user is executing a workflow in a computer game. The user presses some buttons and interacts with the game engine. While the user interacts with the game, a plan trace is created. That means the user's actions are stored in a logfile. The logfile gets transformed into a machine readable notation which is enriched by semantic attributes. The result is a textfile in the LTML syntax which is put on the blackboard. Agents (software programs in the blackboard system) are able to parse the LTML syntax. == Implementations == We start by discussing two well known early blackboard systems, BB1 and GBB, below and then discuss more recent implementations and applications. The BB1 blackboard architecture was originally inspired by studies of how humans plan to perform multiple tasks in a trip, used task-planning as a simplified example of tactical planning for the Office of Naval Research. Hayes-Roth & Hayes-Roth found that human planning was more closely modeled as an opportunistic process, in contrast to the primarily top-down planners used at the time: While not incompatible with successive-refinement models, our view of planning is somewhat different. We share the assumption that planning processes operate in a two-dimensional planning space defined on time and abstraction dimensions. However, we assume that people's planning activity is largely opportunistic. That is, at each point in the process, the planner's current decisions and observations suggest various opportunities for plan development. The planner's subsequent decisions follow up on selected opportunities. Sometimes, these decision-sequences follow an orderly path and produce a neat top-down expansion as described above. However, some decisions and observations might also suggest less orderly opportunities for plan development. A key innovation of BB1 was that it applied this opportunistic planning model to its own control, using the same blackboard model of incremental, opportunistic, problem-solving that was applied to solve domain problems. Meta-level reasoning with control knowledge sources could then monitor whether planning and problem-solving were proceeding as expected or stalled. If stalled, BB1 could switch from one strategy to another as conditions – such as the goals being considered or the time remaining – changed. BB1 was applied in multiple domains: construction site planning, inferring 3-D protein structures from X-ray crystallography, intelligent tutoring systems, and real-time patient monitoring. BB1 also allowed domain-general language frameworks to be designed for wide classes of problems. For example, the ACCORD language framework defined a particular approach to solving configuration problems. The problem-solving approach was to incrementally assemble a solution by adding objects and constraints, one at a time. Actions in the ACCORD language framework appear as short English-like commands or sentences for specifying preferred actions, events to trigger KSes, preconditions to run a KS action, and obviation conditions to discard a KS action that is no longer relevant. GBB focused on efficiency, in contrast to BB1, which focused more on sophisticated reasoning and opportunistic planning. GBB improves efficiency by allowing blackboards to be multi-dimensional, where dimensions can be either ordered or not, and then by increasing the efficiency of pattern matching. GBB1, one of GBB's control shells implements BB1's style of control while adding efficiency improvements. Other well-known of early academic blackboard systems are the Hearsay II speech recognition system and Douglas Hofstadter's Copycat and Numbo projects. Some more recent examples of deployed real-world applications include: The PLAN component of the Mission Control System for RADARSAT-1, an Earth observation satellite developed by Canada to monitor environmental changes and Earth's natural resources. The GTXImage CAD software by GTX Corporation was developed in the early 1990s using a set of rulebases and neural networks as specialists operating on a blackboard system. Adobe Acrobat Capture (now discontinued), as it used a blackboard system to decompose and recognize image pages to understand the objects, text, and fonts on the page. This function is currently built into the retail version of Adobe Acrobat as "OCR Text Recognition". Details of a similar OCR blackboard for Farsi text are in the public domain. Blackboard systems are used routinely in many military C4ISTAR systems for detecting and tracking objects. Another example of current use is in Game AI, where they are considered a standard AI tool to help with adding AI to video games. == Recent developments == Blackboard-like systems have been constructed within modern Bayesian machine learning settings, using agents to add and remove Bayesian network nodes. In these 'Bayesian Blackboard' systems, the heuristics can acquire more rigorous probabilistic meanings as proposal and acceptances in Metropolis Hastings sampling though the space of possible structures. Conversely, using these mappings, existing Metropolis-Hastings samplers over structural spaces may now thus be viewed as forms of blackboard systems even when not named as such by the authors. Such samplers are commonly found in musical transcription algorithms for example. Blackboard systems have also been used to build large-scale intelligent systems for the annotation of media content, automating parts of traditional social science research. In this domain, the problem of integrating various AI algorithms into a single intelligent system arises spontaneously, with blackboards providing a way for a collection of distributed, modular natural language processing algorithm

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