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AI Chat Got — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

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  Biorobotics

  Biorobotics is an interdisciplinary science that combines the fields of biomedical engineering, cybernetics, and robotics to develop new technologies that integrate biology with mechanical systems to develop more efficient communication, alter genetic information, and create machines that imitate biological systems. == Cybernetics == Cybernetics focuses on the communication and system of living organisms and machines that can be applied and combined with multiple fields of study such as biology, mathematics, computer science, engineering, and much more. This discipline falls under the branch of biorobotics because of its combined field of study between biological bodies and mechanical systems. Studying these two systems allows for advanced analysis on the functions and processes of each system as well as the interactions between them. === History === Cybernetic theory is a concept that has existed for centuries, dating back to the era of Plato where he applied the term to refer to the "governance of people". The term cybernetique is seen in the mid-1800s used by physicist André-Marie Ampère. The term cybernetics was popularized in the late 1940s to refer to a discipline that touched on, but was separate, from established disciplines, such as electrical engineering, mathematics, and biology. === Science === Cybernetics is often misunderstood because of the breadth of disciplines it covers. In the early 20th century, it was coined as an interdisciplinary field of study that combines biology, science, network theory, and engineering. Today, it covers all scientific fields with system related processes. The goal of cybernetics is to analyze systems and processes of any system or systems in an attempt to make them more efficient and effective. === Applications === Cybernetics is used as an umbrella term so applications extend to all systems related scientific fields such as biology, mathematics, computer science, engineering, management, psychology, sociology, art, and more. Cybernetics is used amongst several fields to discover principles of systems, adaptation of organisms, information analysis and much more. == Genetic engineering == Genetic engineering is a field that uses advances in technology to modify biological organisms. Through different methods, scientists are able to alter the genetic material of microorganisms, plants and animals to provide them with desirable traits. For example, making plants grow bigger, better, and faster. Genetic engineering is included in biorobotics because it uses new technologies to alter biology and change an organism's DNA for their and society's benefit. === History === Although humans have modified genetic material of animals and plants through artificial selection for millennia (such as the genetic mutations that developed teosinte into corn and wolves into dogs), genetic engineering refers to the deliberate alteration or insertion of specific genes to an organism's DNA. The first successful case of genetic engineering occurred in 1973 when Herbert Boyer and Stanley Cohen were able to transfer a gene with antibiotic resistance to a bacterium. === Science === There are three main techniques used in genetic engineering: The plasmid method, the vector method and the biolistic method. ==== Plasmid method ==== This technique is used mainly for microorganisms such as bacteria. Through this method, DNA molecules called plasmids are extracted from bacteria and placed in a lab where restriction enzymes break them down. As the enzymes do this, some develop a rough edge that resembles that of a staircase which is considered 'sticky' and capable of reconnecting. These 'sticky' molecules are inserted into another bacteria where they will connect to the DNA rings with the altered genetic material. ==== Vector method ==== The vector method is considered a more precise technique than the plasmid method as it involves the transfer of a specific gene instead of a whole sequence. In the vector method, a specific gene from a DNA strand is isolated through restriction enzymes in a laboratory and is inserted into a vector. Once the vector accepts the genetic code, it is inserted into the host cell where the DNA will be transferred. ==== Biolistic method ==== The biolistic method is typically used to alter the genetic material of plants. This method embeds the desired DNA with a metallic particle such as gold or tungsten in a high speed gun. The particle is then bombarded into the plant. Due to the high velocities and the vacuum generated during bombardment, the particle is able to penetrate the cell wall and inserts the new DNA into the cell. === Applications === Genetic engineering has many uses in the fields of medicine, research and agriculture. In the medical field, genetically modified bacteria are used to produce drugs such as insulin, human growth hormones and vaccines. In research, scientists genetically modify organisms to observe physical and behavioral changes to understand the function of specific genes. In agriculture, genetic engineering is extremely important as it is used by farmers to grow crops that are resistant to herbicides and to insects such as BTCorn. == Bionics == Bionics is a medical engineering field and a branch of biorobotics consisting of electrical and mechanical systems that imitate biological systems, such as prosthetics and hearing aids. It's a portmanteau that combines biology and electronics. === History === The history of bionics goes as far back in time as ancient Egypt. A prosthetic toe made out of wood and leather was found on the foot of a mummy. The time period of the mummy corpse was estimated to be from around the fifteenth century B.C. Bionics can also be witnessed in ancient Greece and Rome. Prosthetic legs and arms were made for amputee soldiers. In the early 16th century, a French military surgeon by the name of Ambroise Pare became a pioneer in the field of bionics. He was known for making various types of upper and lower prosthetics. One of his most famous prosthetics, Le Petit Lorrain, was a mechanical hand operated by catches and springs. During the early 19th century, Alessandro Volta further progressed bionics. He set the foundation for the creation of hearing aids with his experiments. He found that electrical stimulation could restore hearing by inserting an electrical implant to the saccular nerve of a patient's ear. In 1945, the National Academy of Sciences created the Artificial Limb Program, which focused on improving prosthetics since there were a large number of World War II amputee soldiers. Since this creation, prosthetic materials, computer design methods, and surgical procedures have improved, creating modern-day bionics. === Science === ==== Prosthetics ==== The important components that make up modern-day prosthetics are the pylon, the socket, and the suspension system. The pylon is the internal frame of the prosthetic that is made up of metal rods or carbon-fiber composites. The socket is the part of the prosthetic that connects the prosthetic to the person's missing limb. The socket consists of a soft liner that makes the fit comfortable, but also snug enough to stay on the limb. The suspension system is important in keeping the prosthetic on the limb. The suspension system is usually a harness system made up of straps, belts or sleeves that are used to keep the limb attached. The operation of a prosthetic could be designed in various ways. The prosthetic could be body-powered, externally-powered, or myoelectrically powered. Body-powered prosthetics consist of cables attached to a strap or harness, which is placed on the person's functional shoulder, allowing the person to manipulate and control the prosthetic as he or she deems fit. Externally-powered prosthetics consist of motors to power the prosthetic and buttons and switches to control the prosthetic. Myoelectrically powered prosthetics are new, advanced forms of prosthetics where electrodes are placed on the muscles above the limb. The electrodes will detect the muscle contractions and send electrical signals to the prosthetic to move the prosthetic. The downside to this type of prosthetic is that if the sensors are not placed correctly on the limb then the electrical impulses will fail to move the prosthetic. TrueLimb is a specific brand of prosthetics that uses myoelectrical sensors which enable a person to have control of their bionic limb. ==== Hearing aids ==== Four major components make up the hearing aid: the microphone, the amplifier, the receiver, and the battery. The microphone takes in outside sound, turns that sound to electrical signals, and sends those signals to the amplifier. The amplifier increases the sound and sends that sound to the receiver. The receiver changes the electrical signal back into sound and sends the sound into the ear. Hair cells in the ear will sense the vibrations from the sound, convert the vibrations into nerve signals, and send it to the brain so

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  Reconstruction from projections

  The problem of reconstructing a multidimensional signal from its projection is uniquely multidimensional, having no 1-D counterpart. It has applications that range from computer-aided tomography to geophysical signal processing. It is a problem which can be explored from several points of view—as a deconvolution problem, a modeling problem, an estimation problem, or an interpolation problem. == Motivation and applications == Many fields in science and engineering use reconstruction from projections, especially in imaging. It is widely applied geophysical tomography, medical imaging and industrial radiography. For example, in a CT scanner, the 3D structure of the patient’s body being scanned is measured with beams going through the tissue and hitting a detector, giving a flat projection of the body from that angle. Multiple projections are put together to get an image of the position and shape of structures inside in 3D. == Problem statement and basics == A projection is a linear mapping of an M {\displaystyle M} dimensional signal into an N {\displaystyle N} dimensional one, where N ≤ M {\displaystyle N\leq M} . And the objective of reconstruction is to restore the M {\displaystyle M} dimensional signal based on the N {\displaystyle N} dimensional signal. The following case is a 2-D signal projected into 1D signal. The signal in the original coordinate is denoted as d ( u , v ) {\displaystyle d(u,v)} . Now consider a collimated beam of radiation coming from the opposite orientation of v ^ {\displaystyle {\hat {v}}} , producing a projection along u ^ {\displaystyle {\hat {u}}} . v ^ {\displaystyle {\hat {v}}} and u ^ {\displaystyle {\hat {u}}} are normal to each other, and the angle between u {\displaystyle u} and u ^ {\displaystyle {\hat {u}}} is theta. The signal obtained along u ^ {\displaystyle {\hat {u}}} axis is defined to be p θ ( u ^ ) {\displaystyle p_{\theta }({\hat {u}})} . The relationship between the original coordinate and the rotated coordinate is given by [ u ^ v ^ ] = [ cos ⁡ θ sin ⁡ θ − sin ⁡ θ cos ⁡ θ ] [ u v ] {\displaystyle {\begin{bmatrix}{\hat {u}}\\{\hat {v}}\end{bmatrix}}={\begin{bmatrix}\cos \theta &\sin \theta \\-\sin \theta &\cos \theta \end{bmatrix}}{\begin{bmatrix}u\\v\end{bmatrix}}} or inversely, [ u v ] = [ cos ⁡ θ − sin ⁡ θ sin ⁡ θ cos ⁡ θ ] [ u ^ v ^ ] {\displaystyle {\begin{bmatrix}u\\v\end{bmatrix}}={\begin{bmatrix}\cos \theta &-\sin \theta \\\sin \theta &\cos \theta \end{bmatrix}}{\begin{bmatrix}{\hat {u}}\\{\hat {v}}\end{bmatrix}}} Then we have p θ ( u ^ ) = ∫ − ∞ ∞ d ( u , v ) d v ^ = ∫ − ∞ ∞ d ( u ^ cos ⁡ ( θ ) − v ^ sin ⁡ ( θ ) , u ^ sin ⁡ ( θ ) + v ^ cos ⁡ ( θ ) ) d v ^ {\displaystyle p_{\theta }({\hat {u}})=\int _{-\infty }^{\infty }d(u,v)\,\mathrm {d} {\hat {v}}=\int _{-\infty }^{\infty }d({\hat {u}}\cos(\theta )-{\hat {v}}\sin(\theta ),{\hat {u}}\sin(\theta )+{\hat {v}}\cos(\theta ))\,\mathrm {d} {\hat {v}}} By varying theta, a large number of projections can be obtained. Given the projection-slice theorem, D ( Ω , θ ) {\displaystyle D(\Omega ,\theta )} ,the slice of the Fourier transform of d ( u , v ) {\displaystyle d(u,v)} at angle theta, is equivalent to P θ ( Ω ) {\displaystyle P_{\theta }(\Omega )} , the Fourier Transform of the projection p θ ( u ^ ) {\displaystyle p_{\theta }({\hat {u}})} . Therefore, the unknown d ( u , v ) {\displaystyle d(u,v)} can be obtained from its Fourier transform by means of the Fourier transform inversion integral d ( u , v ) = 1 4 π 2 ∫ − ∞ ∞ ∫ − ∞ ∞ D ( Ω 1 , Ω 2 ) e j Ω 1 u e j Ω 2 v d Ω 1 , Ω 2 {\displaystyle \mathrm {d} (u,v)={\frac {1}{4\pi ^{2}}}\int _{-\infty }^{\infty }\int _{-\infty }^{\infty }D(\Omega _{1},\Omega _{2})e^{j\Omega _{1}u}e^{j\Omega _{2}v}\,\mathrm {d} \Omega _{1},\Omega _{2}} = 1 4 π 2 ∫ 0 ∞ ∫ − π π D ( Ω , θ ) e j Ω u cos ⁡ ( θ ) e j Ω v s i n θ | Ω | d Ω d θ {\displaystyle ={\frac {1}{4\pi ^{2}}}\int _{0}^{\infty }\int _{-\pi }^{\pi }D(\Omega ,\theta )e^{j\Omega u\cos(\theta )}e^{j\Omega vsin\theta }{\begin{vmatrix}\Omega \end{vmatrix}}\,\mathrm {d} \Omega \mathrm {d} \theta } = 1 4 π 2 ∫ − π π ∫ 0 ∞ P θ ( Ω ) e j Ω ( u cos ⁡ θ + v sin ⁡ θ ) | Ω | d Ω d θ {\displaystyle ={\frac {1}{4\pi ^{2}}}\int _{-\pi }^{\pi }\int _{0}^{\infty }P_{\theta }(\Omega )e^{j}\Omega (u\cos \theta +v\sin \theta ){\begin{vmatrix}\Omega \end{vmatrix}}\,\mathrm {d} \Omega \mathrm {d} \theta } = 1 4 π 2 ∫ 0 π ( ∫ − ∞ ∞ P θ ( Ω ) | Ω | {\displaystyle ={\frac {1}{4\pi ^{2}}}\int _{0}^{\pi }(\int _{-\infty }^{\infty }P_{\theta }(\Omega ){\begin{vmatrix}\Omega \end{vmatrix}}} e j Ω u ^ d Ω ) d θ {\displaystyle e^{j\Omega {\hat {u}}}\mathrm {d} \Omega )\mathrm {d} \theta } By taking the inverse Fourier Transform and assuming g ( u ^ ) = F − 1 ( | Ω | 2 ) {\displaystyle g({\hat {u}})={\mathcal {F}}^{-1}({{\begin{vmatrix}\Omega \end{vmatrix}}^{2}})} , we get d ( u , v ) = ∑ i △ θ i [ p θ ( u ^ ) ∗ g θ i ( u ^ ) ] {\displaystyle d(u,v)=\sum _{i}\vartriangle \theta _{i}[p_{\theta }({\hat {u}})g_{\theta i}({\hat {u}})]} == Approaches == In practice, there are a wide variety of methods that are utilized, most of which are reconstruct 3-D information (volume) from 2-D signals (image). Typically used methods are CT, MRI, PET and SPECT. And the filtered back projection based on the principles introduced above are commonly applied. === Computed Tomography (CT) === In CT, a volume is formed by stacking the axial slices. The software cuts the volume in a different plane (usually orthogonal). Commonly, slice data is generated using an X-ray source that rotates around the object. X-ray sensors are positioned on the opposite side of the circle from the X-ray source. === Magnetic resonance imaging (MRI) === In MRI, energy from an oscillating magnetic field is temporarily applied to the patient at the appropriate resonance frequency. The protons (hydrogen atoms) emit a radio frequency signal which is measured by a receiving coil. The radio signal can be made to encode position information by varying the main magnetic field using gradient coils. === Positron emission tomography (PET) === The system detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), which is introduced into the body on a biologically active molecule. Three-dimensional images of tracer concentration within the body are then constructed by computer analysis. In modern PET-CT scanners, three dimensional imaging is often accomplished with the aid of a CT X-ray scan performed on the patient during the same session, in the same machine. === Single-photon emission computed tomography (SPECT) === SPECT imaging is performed by using a gamma camera to acquire multiple 2-D images (projections) from multiple angles. Multiple projections are used to yield a 3-D data set. This data set may then be manipulated to show thin slices along any chosen axis of the body. SPECT is similar to PET in its use of radioactive tracer material and detection of gamma rays, while the tracers used in SPECT emit gamma radiation that is measured more directly.

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  Desktop Window Manager

  Desktop Window Manager (DWM, previously Desktop Compositing Engine or DCE in builds of pre-reset Windows Longhorn) is the compositing window manager in Microsoft Windows since Windows Vista that enables the use of hardware acceleration to render the graphical user interface of Windows. It was originally created to enable portions of the new "Windows Aero" user experience, which allowed for effects such as transparency, 3D window switching and more. It is also included with Windows Server 2008, but requires the "Desktop Experience" feature and compatible graphics drivers to be installed. == Architecture == The Desktop Window Manager is a compositing window manager, meaning that each program has a buffer that it writes data to; DWM then composites each program's buffer into a final image. By comparison, the stacking window manager in Windows XP and earlier (and also Windows Vista and Windows 7 with Windows Aero disabled) comprises a single display buffer to which all programs write. DWM works in different ways depending on the operating system (Windows 7 or Windows Vista) and on the version of the graphics drivers it uses (WDDM 1.0 or 1.1). Under Windows 7 and with WDDM 1.1 drivers, DWM only writes the program's buffer to the video RAM, even if it is a graphics device interface (GDI) program. This is because Windows 7 supports (limited) hardware acceleration for GDI and in doing so does not need to keep a copy of the buffer in system RAM so that the CPU can write to it. Because the compositor has access to the graphics of all applications, it easily allows visual effects that string together visuals from multiple applications, such as transparency. DWM uses DirectX to perform the function of compositing and rendering in the GPU, freeing the CPU of the task of managing the rendering from the off-screen buffers to the display. However, it does not affect applications painting to the off-screen buffers – depending on the technologies used for that, this might still be CPU-bound. DWM-agnostic rendering techniques like GDI are redirected to the buffers by rendering the user interface (UI) as bitmaps. DWM-aware rendering technologies like WPF directly make the internal data structures available in a DWM-compatible format. The window contents in the buffers are then converted to DirectX textures. The desktop itself is a full-screen Direct3D surface, with windows being represented as a mesh consisting of two adjacent (and mutually inverted) triangles, which are transformed to represent a 2D rectangle. The texture, representing the UI chrome, is then mapped onto these rectangles. Window transitions are implemented as transformations of the meshes, using shader programs. With Windows Vista, the transitions are limited to the set of built-in shaders that implement the transformations. Greg Schechter, a developer at Microsoft has suggested that this might be opened up for developers and users to plug in their own effects in a future release. DWM only maps the primary desktop object as a 3D surface; other desktop objects, including virtual desktops as well as the secure desktop used by User Account Control are not. Because all applications render to an off-screen buffer, they can be read off the buffer embedded in other applications as well. Since the off-screen buffer is constantly updated by the application, the embedded rendering will be a dynamic representation of the application window and not a static rendering. This is how the live thumbnail previews and Windows Flip work in Windows Vista and Windows 7. DWM exposes a public API that allows applications to access these thumbnail representations. The size of the thumbnail is not fixed; applications can request the thumbnails at any size - smaller than the original window, at the same size or even larger - and DWM will scale them properly before returning. Aero Flip does not use the public thumbnail APIs as they do not allow for directly accessing the Direct3D textures. Instead, Aero Flip is implemented directly in the DWM engine. The Desktop Window Manager uses Media Integration Layer (MIL), the unmanaged compositor which it shares with Windows Presentation Foundation, to represent the windows as composition nodes in a composition tree. The composition tree represents the desktop and all the windows hosted in it, which are then rendered by MIL from the back of the scene to the front. Since all the windows contribute to the final image, the color of a resultant pixel can be decided by more than one window. This is used to implement effects such as per-pixel transparency. DWM allows custom shaders to be invoked to control how pixels from multiple applications are used to create the displayed pixel. The DWM includes built-in Pixel Shader 2.0 programs which compute the color of a pixel in a window by averaging the color of the pixel as determined by the window behind it and its neighboring pixels. These shaders are used by DWM to achieve the blur effect in the window borders of windows managed by DWM, and optionally for the areas where it is requested by the application. Since MIL provides a retained mode graphics system by caching the composition trees, the job of repainting and refreshing the screen when windows are moved is handled by DWM and MIL, freeing the application of the responsibility. The background data is already in the composition tree and the off-screen buffers and is directly used to render the background. In pre-Vista Windows OSs, background applications had to be requested to re-render themselves by sending them the WM_PAINT message. DWM uses double-buffered graphics to prevent flickering and tearing when moving windows. The compositing engine uses optimizations such as culling to improve performance, as well as not redrawing areas that have not changed. Because the compositor is multi-monitor aware, DWM natively supports this too. During full-screen applications, such as games, DWM does not perform window compositing and therefore performance will not appreciably decrease. On Windows 8 and Windows Server 2012, DWM is used at all times and cannot be disabled, due to the new "start screen experience" implemented. Since the DWM process is usually required to run at all times on Windows 8, users experiencing an issue with the process are seeing memory usage decrease after a system reboot. This is often the first step in a long list of troubleshooting tasks that can help. It is possible to prevent DWM from restarting temporarily in Windows 8, which causes the desktop to turn black, the taskbar grey, and break the start screen/modern apps, but desktop apps will continue to function and appear just like Windows 7 and Vista's Basic theme, based on the single-buffer renderer used by XP. They also use Windows 8's centered title bar, visible within Windows PreInstallation Environment. Starting up Windows without DWM will not work because the default lock screen requires DWM unlike the fallback lockscreen that appears as a command line interface program when Windows.UI.Logon.dll isn't present on Windows versions such as 1507 and later, so it can only be done on the fly, and does not have any practical purposes. Starting with Windows 10, disabling DWM in such a way will cause the entire compositing engine to break, even traditional desktop apps, due to Universal App implementations in the taskbar and new start menu. Windows can still be partially usable without the presence of DWM but requires Sihost.exe to not be present due to it relying on DWM. Most of the applications in Windows 11 require DWM to render UI elements and transparency, Windows 11's new task manager requires dwm to render menus unlike the fallback -d version. Unlike its predecessors, Windows 8 supports basic display adapters through Windows Advanced Rasterization Platform (WARP), which uses software rendering and the CPU to render the interface rather than the graphics card. This allows DWM to function without compatible drivers, but not at the same level of performance as with a normal graphics card. DWM on Windows 8 also adds support for stereoscopic 3D. == Redirection == For rendering techniques that are not DWM-aware, output must be redirected to the DWM buffers. With Windows, either GDI or DirectX can be used for rendering. To make these two work with DWM, redirection techniques for both are provided. With GDI, which is the most used UI rendering technique in Microsoft Windows, each application window is notified when it or a part of it comes in view and it is the job of the application to render itself. Without DWM, the rendering rasterizes the UI in a buffer in video memory, from where it is rendered to the screen. Under DWM, GDI calls are redirected to use the Canonical Display Driver (cdd.dll), a software renderer. A buffer equal to the size of the window is allocated in system memory and CDD.DLL outputs to this buffer rather than the video memory. Another buffer is allocated in the video memory to represent t

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  EasyA

  EasyA is a web3 technology company and education platform based in London (United Kingdom), founded in 2022 by Phil Kwok and Dom Kwok. EasyA was officially launched in 2022, focusing on web3 technologies. This community was influenced by the founders' experiences during the COVID-19 pandemic and early collaborations with universities and other educational institutions. Subsequently, the community was used as a foundation for developing Web3-related initiatives, including the organisation of EasyA's first Web3 hackathon in 2022. The EasyA app has over one million users and provides educational content on various blockchain technologies. EasyA Labs is a separate initiative focused on developing products intended to improve accessibility to cryptocurrency for a broader audience.

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  Nvidia Omniverse

  Omniverse is a real-time 3D graphics collaboration platform created by Nvidia. It has been used for applications in the visual effects and "digital twin" industrial simulation industries. Omniverse makes extensive use of the Universal Scene Description (USD) format. == Third-party Integrations == Omniverse supports integration with external computer-aided design tools through third-party connectors. For example, academic work has demonstrated a connector linking Omniverse with the open-source CAD system FreeCAD, enabling collaborative access to CAD geometry via the Omniverse Nucleus server and extending Omniverse usage beyond media and entertainment workflows.

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  Level set (data structures)

  In computer science, a level set is a data structure designed to represent discretely sampled dynamic level sets of functions. A common use of this form of data structure is in efficient image rendering. The underlying method constructs a signed distance field that extends from the boundary, and can be used to solve the motion of the boundary in this field. == Chronological developments == The powerful level-set method is due to Osher and Sethian 1988. However, the straightforward implementation via a dense d-dimensional array of values, results in both time and storage complexity of O ( n d ) {\displaystyle O(n^{d})} , where n {\displaystyle n} is the cross sectional resolution of the spatial extents of the domain and d {\displaystyle d} is the number of spatial dimensions of the domain. === Narrow band === The narrow band level set method, introduced in 1995 by Adalsteinsson and Sethian, restricted most computations to a thin band of active voxels immediately surrounding the interface, thus reducing the time complexity in three dimensions to O ( n 2 ) {\displaystyle O(n^{2})} for most operations. Periodic updates of the narrowband structure, to rebuild the list of active voxels, were required which entailed an O ( n 3 ) {\displaystyle O(n^{3})} operation in which voxels over the entire volume were accessed. The storage complexity for this narrowband scheme was still O ( n 3 ) . {\displaystyle O(n^{3}).} Differential constructions over the narrow band domain edge require careful interpolation and domain alteration schemes to stabilise the solution. === Sparse field === This O ( n 3 ) {\displaystyle O(n^{3})} time complexity was eliminated in the approximate "sparse field" level set method introduced by Whitaker in 1998. The sparse field level set method employs a set of linked lists to track the active voxels around the interface. This allows incremental extension of the active region as needed without incurring any significant overhead. While consistently O ( n 2 ) {\displaystyle O(n^{2})} efficient in time, O ( n 3 ) {\displaystyle O(n^{3})} storage space is still required by the sparse field level set method. See for implementation details. === Sparse block grid === The sparse block grid method, introduced by Bridson in 2003, divides the entire bounding volume of size n 3 {\displaystyle n^{3}} into small cubic blocks of m 3 {\displaystyle m^{3}} voxels each. A coarse grid of size ( n / m ) 3 {\displaystyle (n/m)^{3}} then stores pointers only to those blocks that intersect the narrow band of the level set. Block allocation and deallocation occur as the surface propagates to accommodate to the deformations. This method has a suboptimal storage complexity of O ( ( n m ) 3 + m 3 n 2 ) {\displaystyle O\left((nm)3+m^{3}n^{2}\right)} , but retains the constant time access inherent to dense grids. === Octree === The octree level set method, introduced by Strain in 1999 and refined by Losasso, Gibou and Fedkiw, and more recently by Min and Gibou uses a tree of nested cubes of which the leaf nodes contain signed distance values. Octree level sets currently require uniform refinement along the interface (i.e. the narrow band) in order to obtain sufficient precision. This representation is efficient in terms of storage, O ( n 2 ) , {\displaystyle O(n^{2}),} and relatively efficient in terms of access queries, O ( log n ) . {\displaystyle O(\log \,n).} An advantage of the level method on octree data structures is that one can solve the partial differential equations associated with typical free boundary problems that use the level set method. The CASL research group has developed this line of work in computational materials, computational fluid dynamics, electrokinetics, image-guided surgery and controls. === Run-length encoded === The run-length encoding (RLE) level set method, introduced in 2004, applies the RLE scheme to compress regions away from the narrow band to just their sign representation while storing with full precision the narrow band. The sequential traversal of the narrow band is optimal and storage efficiency is further improved over the octree level set. The addition of an acceleration lookup table allows for fast O ( log ⁡ r ) {\displaystyle O(\log r)} random access, where r is the number of runs per cross section. Additional efficiency is gained by applying the RLE scheme in a dimensional recursive fashion, a technique introduced by Nielsen & Museth's similar DT-Grid. === Hash Table Local Level Set === The Hash Table Local Level Set method was introduced in 2011 by Eyiyurekli and Breen and extended in 2012 by Brun, Guittet, and Gibou, only computes the level set data in a band around the interface, as in the Narrow Band Level-Set Method, but also only stores the data in that same band. A hash table data structure is used, which provides an O ( 1 ) {\displaystyle O(1)} access to the data. However, Brun et al. conclude that their method, while being easier to implement, performs worse than a quadtree implementation. They find that as it is, [...] a quadtree data structure seems more adapted than the hash table data structure for level-set algorithms. Three main reasons for worse efficiency are listed: to obtain accurate results, a rather large band is required close to the interface, which counterbalances the absence of grid nodes far from the interface; the performances are deteriorated by extrapolation procedures on the outer edges of the local grid and the width of the band restricts the time step and slows down the method. === Point-based === Corbett in 2005 introduced the point-based level set method. Instead of using a uniform sampling of the level set, the continuous level set function is reconstructed from a set of unorganized point samples via moving least squares.

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  PNGOUT

  PNGOUT is a freeware command line optimizer for PNG images written by Ken Silverman. The transformation is lossless, meaning that the resulting image is visually identical to the source image. According to its author, this program can often get higher compression than other optimizers by 5–10%. It is possible to compress some inflated PNGs to a size below 1% of the original file. PNGOUT was also available as a plug-in for the freeware image viewer IrfanView and can be enabled as an option when saving files. It allows editing of various PNGOUT settings via a dialog box. PNGOUT integration was removed in IrfanView version 4.58 in favour of OptiPNG. In 2006, a commercial version of PNGOUT with a graphical user interface, known as PNGOUTWin, was released by Ardfry Imaging, a small company Silverman co-founded in 2005. There is also a freeware GUI frontend to PNGOUT available, known as PNGGauntlet. == Main operation == The main function of PNGOUT is to reduce the size of image data contained in the IDAT chunk. This chunk is compressed using the deflate algorithm. Deflate algorithms can vary in speed and compression ratio, with higher compression ratios generally implying lower speed. Ken Silverman wrote a deflate compressor for PNGOUT that is slower than the ones used in most graphics software, but produces smaller files. PNGOUT also performs automatic bit depth, color, and palette reduction where appropriate.

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  FMLLR

  In signal processing, Feature space Maximum Likelihood Linear Regression (fMLLR) is a global feature transform that are typically applied in a speaker adaptive way, where fMLLR transforms acoustic features to speaker adapted features by a multiplication operation with a transformation matrix. In some literature, fMLLR is also known as the Constrained Maximum Likelihood Linear Regression (cMLLR). == Overview == fMLLR transformations are trained in a maximum likelihood sense on adaptation data. These transformations may be estimated in many ways, but only maximum likelihood (ML) estimation is considered in fMLLR. The fMLLR transformation is trained on a particular set of adaptation data, such that it maximizes the likelihood of that adaptation data given a current model-set. This technique is a widely used approach for speaker adaptation in HMM-based speech recognition. Later research also shows that fMLLR is an excellent acoustic feature for DNN/HMM hybrid speech recognition models. The advantage of fMLLR includes the following: the adaptation process can be performed within a pre-processing phase, and is independent of the ASR training and decoding process. this type of adapted feature can be applied to deep neural networks (DNN) to replace traditionally used mel-spectrogram in end-to-end speech recognition models. fMLLR's speaker adaptation process leads to a significant performance boost for ASR models, hence outperforming other transform or features like MFCCs (Mel-Frequency Cepstral Coefficients) and FBANKs (Filter bank) coefficients. fMLLR features can be efficiently realized with speech toolkits like Kaldi. Major problem and disadvantage of fMLLR: when the amount of adaptation data is limited, the transformation matrices tends to easily overfit the given data. == Computing fMLLR transform == Feature transform of fMLLR can be easily computed with the open source speech tool Kaldi, the Kaldi script uses the standard estimation scheme described in Appendix B of the original paper, in particular the section Appendix B.1 "Direct method over rows". In the Kaldi formulation, fMLLR is an affine feature transform of the form x {\displaystyle x} → A {\displaystyle A} x {\displaystyle x} + b {\displaystyle +b} , which can be written in the form x {\displaystyle x} →W x ^ {\displaystyle {\hat {x}}} , where x ^ {\displaystyle {\hat {x}}} = [ x 1 ] {\displaystyle {\begin{bmatrix}x\\1\end{bmatrix}}} is the acoustic feature x {\displaystyle x} with a 1 appended. Note that this differs from some of the literature where the 1 comes first as x ^ {\displaystyle {\hat {x}}} = [ 1 x ] {\displaystyle {\begin{bmatrix}1\\x\end{bmatrix}}} . The sufficient statistics stored are: K = ∑ t , j , m γ j , m ( t ) Σ j m − 1 μ j m x ( t ) + {\displaystyle K=\sum _{t,j,m}\gamma _{j,m}(t)\textstyle \Sigma _{jm}^{-1}\mu _{jm}x(t)^{+}\displaystyle } where Σ j m − 1 {\displaystyle \textstyle \Sigma _{jm}^{-1}\displaystyle } is the inverse co-variance matrix. And for 0 ≤ i ≤ D {\displaystyle 0\leq i\leq D} where D {\displaystyle D} is the feature dimension: G ( i ) = ∑ t , j , m γ j , m ( t ) ( 1 σ j , m 2 ( i ) ) x ( t ) + x ( t ) + T {\displaystyle G^{(i)}=\sum _{t,j,m}\gamma _{j,m}(t)\left({\frac {1}{\sigma _{j,m}^{2}(i)}}\right)x(t)^{+}x(t)^{+T}\displaystyle } For a thorough review that explains fMLLR and the commonly used estimation techniques, see the original paper "Maximum likelihood linear transformations for HMM-based speech recognition ". Note that the Kaldi script that performs the feature transforms of fMLLR differs with by using a column of the inverse in place of the cofactor row. In other words, the factor of the determinant is ignored, as it does not affect the transform result and can causes potential danger of numerical underflow or overflow. == Comparing with other features or transforms == Experiment result shows that by using the fMLLR feature in speech recognition, constant improvement is gained over other acoustic features on various commonly used benchmark datasets (TIMIT, LibriSpeech, etc). In particular, fMLLR features outperform MFCCs and FBANKs coefficients, which is mainly due to the speaker adaptation process that fMLLR performs. In, phoneme error rate (PER, %) is reported for the test set of TIMIT with various neural architectures: As expected, fMLLR features outperform MFCCs and FBANKs coefficients despite the use of different model architecture. Where MLP (multi-layer perceptron) serves as a simple baseline, on the other hand RNN, LSTM, and GRU are all well known recurrent models. The Li-GRU architecture is based on a single gate and thus saves 33% of the computations over a standard GRU model, Li-GRU thus effectively address the gradient vanishing problem of recurrent models. As a result, the best performance is obtained with the Li-GRU model on fMLLR features. == Extract fMLLR features with Kaldi == fMLLR can be extracted as reported in the s5 recipe of Kaldi. Kaldi scripts can certainly extract fMLLR features on different dataset, below are the basic example steps to extract fMLLR features from the open source speech corpora Librispeech. Note that the instructions below are for the subsets train-clean-100,train-clean-360,dev-clean, and test-clean, but they can be easily extended to support the other sets dev-other, test-other, and train-other-500. These instruction are based on the codes provided in this GitHub repository, which contains Kaldi recipes on the LibriSpeech corpora to execute the fMLLR feature extraction process, replace the files under $KALDI_ROOT/egs/librispeech/s5/ with the files in the repository. Install Kaldi. Install Kaldiio. If running on a single machine, change the following lines in $KALDI_ROOT/egs/librispeech/s5/cmd.sh to replace queue.pl to run.pl: Change the data path in run.sh to your LibriSpeech data path, the directory LibriSpeech/ should be under that path. For example: Install flac with: sudo apt-get install flac Run the Kaldi recipe run.sh for LibriSpeech at least until Stage 13 (included), for simplicity you can use the modified run.sh. Copy exp/tri4b/trans. files into exp/tri4b/decode_tgsmall_train_clean_/ with the following command: Compute the fMLLR features by running the following script, the script can also be downloaded here: Compute alignments using: Apply CMVN and dump the fMLLR features to new .ark files, the script can also be downloaded here: Use the Python script to convert Kaldi generated .ark features to .npy for your own dataloader, an example Python script is provided:

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  Database dump

  A database dump contains a record of the table structure and/or the data from a database and is usually in the form of a list of SQL statements ("SQL dump"). A database dump is most often used for backing up a database so that its contents can be restored in the event of data loss. Corrupted databases can often be recovered by analysis of the dump. Database dumps are often published by free content projects, to facilitate reuse, forking, offline use, and long-term digital preservation. Dumps can be transported into environments with Internet blackouts or otherwise restricted Internet access, as well as facilitate local searching of the database using sophisticated tools such as grep.

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  Alexis Spectral Data

  Alexis Spectral Data is a software developed for colour matching processes that calculates from available spectral data the colour numbers used by computers to display colours on screen. It displays the colour for each spectral reflectance curve and records the calculated trichromatic values and colour numbers along with the spectral curves. This eliminates the need to scan the samples separately with a truecolour Scanner while creating the database. The spectral data can be introduced manually as a series of reflectance values at wavelengths measured in different standard illuminants with an arbitrary but fixed increment that must be kept for each spectral curve throughout the creation of the whole database. Therefore, older UV-VIS Spectrophotometers that can't be interfaced with computers can also be used for creating the database needed for colour matching. Alexis Spectral Data determines the whiteness degree in a less time-consuming method, which permits storage and easier handling of the obtained data. Alexis Spectral Data can export the trichromatic values, calculated from the spectral curves, to Alexis Analyser, software that handles only trichromatic data. The earliest information about the development of this software comes from a paper published by a student at the University Politehnica Bucharest in 1993. The software runs on Windows based computers but not on other operating systems.

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  Signal-to-noise ratio (imaging)

  Signal-to-noise ratio (SNR) is used in imaging to characterize image quality. The sensitivity of a (digital or film) imaging system is typically described in the terms of the signal level that yields a threshold level of SNR. Industry standards define sensitivity in terms of the ISO film speed equivalent, using SNR thresholds (at average scene luminance) of 40:1 for "excellent" image quality and 10:1 for "acceptable" image quality. SNR is sometimes quantified in decibels (dB) of signal power relative to noise power, though in the imaging field the concept of "power" is sometimes taken to be the power of a voltage signal proportional to optical power; so a 20 dB SNR may mean either 10:1 or 100:1 optical power, depending on which definition is in use. == Definition of SNR == Traditionally, SNR is defined to be the ratio of the average signal value μ s i g {\displaystyle \mu _{\mathrm {sig} }} to the standard deviation of the signal σ s i g {\displaystyle \sigma _{\mathrm {sig} }} : S N R = μ s i g σ s i g {\displaystyle \mathrm {SNR} ={\frac {\mu _{\mathrm {sig} }}{\sigma _{\mathrm {sig} }}}} when the signal is an optical intensity, or as the square of this value if the signal and noise are viewed as amplitudes (field quantities).

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  BabyCenter

  BabyCenter is an online media company based in San Francisco, New York City, Chicago, and Los Angeles that provides information on conception, pregnancy, birth, and early childhood development for parents and expecting parents. BabyCenter operates 8 country and region specific properties including websites, apps, emails, print publications, and an online community where parents can connect on a variety of topics. The visitors of website and the users of the app can sign up for free weekly email newsletters that guide them through pregnancy and their child's development. In addition to publishing detailed, medically reviewed information about pregnancy and parenting, BabyCenter, under its Mission Motherhood initiative, ran numerous social programs and has participated in public health initiatives in partnership with hospitals, healthcare agencies, nonprofits, NGOs, and government agencies to provide pregnancy and parenting advice. It also annually publishes the most popular baby names. BabyCenter LLC is part of the Everyday Health Group, a division of Ziff Davis. == History == BabyCenter was founded in October 1997 by Stanford University MBA graduates Matt Glickman and Mark Selcow, who recognized a need for information about pregnancy and parenting on the internet. BabyCenter was initially funded through $13.5 million in startup capital funding from venture capital firms, including Bessemer Venture Partners, Intel, and Trinity Ventures. The funds were used to open the BabyCenter Store in October 1998. In the early years of its operation, BabyCenter offered multiple resources and services for parents, including a website that provided medically reviewed information and guidance to new and expectant parents on such topics as fertility, labor, and childcare; a weekly email for pregnant women tailored to their week of pregnancy (based on their pregnancy due date); and community groups and chat rooms for pregnant couples and parents to discuss pregnancy and child-rearing strategies. The site grew quickly, and by early 1999 had 175 employees and an annual revenue of $35 million. In April of that year, the two founders sold BabyCenter to another website, eToys.com, for $190 million in stock. Twenty-three months later, in 2001, shortly before declaring bankruptcy, eToys sold the site to Johnson & Johnson for $10 million. During the eToys ownership, BabyCenter launched its first international E-commerce site in the UK during the spring of 2000. Starting in 2005, BabyCenter launched an expansion plan, extending its global network to Australia, Canada and other countries, staffing each outpost with local editors. In 2007, BabyCenter debuted a Mandarin-language site in China, initiated operations in India, launched a Spanish language website, and introduced its first mobile site. BabyCenter released My Pregnancy Today, its first mobile app, to Apple's App Store in August 2010 and to the Android market in April 2011. The app provided daily information, nutrition tips, advice relevant to the user's week of pregnancy, and 3-D animated videos showcasing a baby's development in utero. The My Pregnancy app was joined by a My Baby Today app in October 2011. In 2015, BabyCenter released Mom Feed, its first mobile app for parents of toddlers and older children (ages 1 to 8). Mom Feed offered personalized, stage-based information as well as content from the BabyCenter Community and Blog in a real-time stream. In 2016, BabyCenter launched its web-based Baby Names Finder. In 2018, Mom Feed was discontinued and BabyCenter replaced that experience with a separate Child Health content area on its website. Also in 2018, BabyCenter launched its mobile baby name generator, the Baby Names app, which, like the web-based Baby Names Finder, leverages data from hundreds of thousands of parents that culminates in its annual most popular Baby Names Report. In 2019, Johnson & Johnson sold Baby Center to Everyday Health Group, a division of New York-based parent company of Ziff Davis, Inc. Neither side disclosed terms of the deal. == Popular research == BabyCenter's most popular baby names is released annually and often cited by the media. In March 2024, BabyCenter did a review of the app Temu and said that the website has found products that have been recalled, could be counterfeit or circumvent U.S. safety standards and features that are important in preventing issues like choking. In 2025, BabyCenter released a report about the cost of raising a newborn baby in the first year. == Content and products == === Websites === BabyCenter has 8 country and region-specific websites around the world, including sites for the United States, Canada, Australia, Brazil, India, Germany, the United Kingdom, and Latin America. Users can find parenting and pregnancy advice in seven languages: English, Spanish, Portuguese, Arabic, French, German, and Hindi BabyCenter content for each country- or region-specific site is written by an editorial team based in that country or region. Medical and health content for each site is reviewed by a medical advisory board based there and adheres to that country or region's medical standards. For example, the U.S. site works with and follows the recommendations of such U.S. medical authorities as the American Academy of Pediatrics, the American Congress of Obstetrics & Gynecology and the Society for Maternal-Fetal Medicine. BabyCenter regularly conducts research and provides thought leadership on pregnancy and parenting topics, popularly cited by major media outlets including The Wall Street Journal, Forbes, The Washington Post, BuzzFeed, Insider, MarketWatch, Axios. === Community, blogs and social === From its earliest days, BabyCenter has had a community area that allows people to join a group of parents with children born in the same month, known as a Birth Club. BabyCenter launched a blog called Momformation in 2007. Eventually, the name was changed to BabyCenter Blog. In April 2021, the BabyCenter Community was identified in a research article within the journal PLOS Computational Biology as facilitating "unobstructed communication" between parents, which avoids the "strong echo chamber phenomena" that can foster and perpetuate vaccine misinformation. === My Pregnancy and Baby Today App === The app is available in six languages, although not all features are supported for every market. Initially the apps only featured pregnancy articles that could be found on the BabyCenter website, but over the years the feature set has expanded to include a growing list of app-specific tools such as weekly fetal development information, a kick tracker, a birth plan worksheet, a contraction timer, a baby growth tracker, a photo journal for pregnant women to record their pregnancy bellies, and a photo journal for documenting a baby's first year. === Mission Motherhood™ === BabyCenter was a cofounder of the Mobile Alliance for Maternal Action (MAMA), a public-private partnership between USAID, Johnson & Johnson, the UN Foundation, and BabyCenter from 2011 to-to 2015. The MAMA program sparked the creation of MomConnect, an initiative of the South African Department of Health for which BabyCenter developed SMS messages with health information about pregnancy and a child's first year of life. BabyCenter helped develop similar messages for mMitra, a voice messaging program in India. A research article in the Maternal and Child Health Journal stated the mMitra program offered strong evidence "that tailored mobile phone voice messages can improve key infant care knowledge and practices that lead to improved infant health outcomes in low-resource settings. BabyCenter's Mission Motherhood Messages were available to qualifying organizations on the BabyCenter website. BabyCenter contributed websites for Free Basics. These websites featured age and stage-based pregnancy and baby articles targeted to low-income, lower-education women who would not otherwise have access to health information. Content developed for this program was also used to support a UNICEF SMS program during the 2016 Zika outbreak. == Awards and recognition == In 1998, BabyCenter won a Webby Award for Best Home Site. Since then, it has been nominated for a Webby Award 19 times and won either a Webby or a People's Choice Webby Award 12 times – including a People's Voice win in 2021 for Lifestyle websites and mobile sites. In 2002, it won Service Journalism award from Online Journalism Awards (OJA). In 2015, BabyCenter won five Digital Health Awards for content about autism in children. In 2016, BabyCenter won seven Digital Health Awards: four for videos about the aches and pains of pregnancy, baby sleep, and the walking milestone in child development; two for articles about baby sleep training and sleep apnea in babies; and one for the BabyCenter mobile app My Pregnancy & Baby Today. In 2021, Forbes Health chose My Pregnancy & Baby Today as the best pregnancy app of 2021, and Women's Health identified it

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  Two-phase locking

  In databases and transaction processing, two-phase locking (2PL) is a pessimistic concurrency control method that guarantees conflict-serializability. It is also the name of the resulting set of database transaction schedules (histories). The protocol uses locks, applied by a transaction to data, which may block (interpreted as signals to stop) other transactions from accessing the same data during the transaction's life. By the 2PL protocol, locks are applied and removed in two phases: Expanding phase: locks are acquired and no locks are released. Shrinking phase: locks are released and no locks are acquired. Two types of locks are used by the basic protocol: Shared and Exclusive locks. Refinements of the basic protocol may use more lock types. Using locks that block processes, 2PL, S2PL, and SS2PL may be subject to deadlocks that result from the mutual blocking of two or more transactions. == Read and write locks == Locks are used to guarantee serializability. A transaction is holding a lock on an object if that transaction has acquired a lock on that object which has not yet been released. For 2PL, the only used data-access locks are read-locks (shared locks) and write-locks (exclusive locks). Below are the rules for read-locks and write-locks: A transaction is allowed to read an object if and only if it is holding a read-lock or write-lock on that object. A transaction is allowed to write an object if and only if it is holding a write-lock on that object. A schedule (i.e., a set of transactions) is allowed to hold multiple locks on the same object simultaneously if and only if none of those locks are write-locks. If a disallowed lock attempts on being held simultaneously, it will be blocked. == Variants == Note that all conflict serializable schedules are also view serializable (but not vice-versa). === Two-phase locking === According to the two-phase locking protocol, each transaction handles its locks in two distinct, consecutive phases during the transaction's execution: Expanding phase (aka Growing phase): locks are acquired and no locks are released (the number of locks can only increase). Shrinking phase (aka Contracting phase): locks are released and no locks are acquired. The two phase locking rules can be summarized as: each transaction must never acquire a lock after it has released a lock. The serializability property is guaranteed for a schedule with transactions that obey this rule. Typically, without explicit knowledge in a transaction on end of phase 1, the rule is safely determined only when a transaction has completed processing and requested commit. In this case, all the locks can be released at once (phase 2). === Conservative two-phase locking === Conservative two-phase locking (C2PL) differs from 2PL in that transactions obtain all the locks they need before the actual execution begins. This is to ensure that a transaction that already holds some locks will not block waiting for other locks. C2PL prevents deadlocks. In cases of heavy lock contention, C2PL reduces the time locks are held on average, relative to 2PL and Strict 2PL, because transactions that hold locks are never blocked. In light lock contention, C2PL holds more locks than is necessary, because it is difficult to predict which locks will be needed in the future, thus leading to higher overhead. A C2PL transaction will not obtain any locks if it cannot obtain all the locks it needs in its initial request. Furthermore, each transaction needs to declare its read and write set (the data items that will be read/written), which is not always possible. Because of these limitations, C2PL is not used very frequently. === Strict two-phase locking === To comply with the strict two-phase locking (S2PL) protocol, a transaction needs to comply with 2PL, and release its write (exclusive) locks only after the transaction has ended (i.e., either committed or aborted). On the other hand, read (shared) locks are released regularly during the shrinking phase. Unlike 2PL, S2PL provides strictness (a special case of cascade-less recoverability). This protocol is not appropriate in B-trees because it causes Bottleneck (while B-trees always starts searching from the parent root). === Strong strict two-phase locking === or Rigorousness, or Rigorous scheduling, or Rigorous two-phase locking To comply with strong strict two-phase locking (SS2PL), a transaction's read and write locks are released only after that transaction has ended (i.e., either committed or aborted). A transaction obeying SS2PL has only a phase 1 and lacks a phase 2 until the transaction has completed. Every SS2PL schedule is also an S2PL schedule, but not vice versa.

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  Biorobotics

  Biorobotics is an interdisciplinary science that combines the fields of biomedical engineering, cybernetics, and robotics to develop new technologies that integrate biology with mechanical systems to develop more efficient communication, alter genetic information, and create machines that imitate biological systems. == Cybernetics == Cybernetics focuses on the communication and system of living organisms and machines that can be applied and combined with multiple fields of study such as biology, mathematics, computer science, engineering, and much more. This discipline falls under the branch of biorobotics because of its combined field of study between biological bodies and mechanical systems. Studying these two systems allows for advanced analysis on the functions and processes of each system as well as the interactions between them. === History === Cybernetic theory is a concept that has existed for centuries, dating back to the era of Plato where he applied the term to refer to the "governance of people". The term cybernetique is seen in the mid-1800s used by physicist André-Marie Ampère. The term cybernetics was popularized in the late 1940s to refer to a discipline that touched on, but was separate, from established disciplines, such as electrical engineering, mathematics, and biology. === Science === Cybernetics is often misunderstood because of the breadth of disciplines it covers. In the early 20th century, it was coined as an interdisciplinary field of study that combines biology, science, network theory, and engineering. Today, it covers all scientific fields with system related processes. The goal of cybernetics is to analyze systems and processes of any system or systems in an attempt to make them more efficient and effective. === Applications === Cybernetics is used as an umbrella term so applications extend to all systems related scientific fields such as biology, mathematics, computer science, engineering, management, psychology, sociology, art, and more. Cybernetics is used amongst several fields to discover principles of systems, adaptation of organisms, information analysis and much more. == Genetic engineering == Genetic engineering is a field that uses advances in technology to modify biological organisms. Through different methods, scientists are able to alter the genetic material of microorganisms, plants and animals to provide them with desirable traits. For example, making plants grow bigger, better, and faster. Genetic engineering is included in biorobotics because it uses new technologies to alter biology and change an organism's DNA for their and society's benefit. === History === Although humans have modified genetic material of animals and plants through artificial selection for millennia (such as the genetic mutations that developed teosinte into corn and wolves into dogs), genetic engineering refers to the deliberate alteration or insertion of specific genes to an organism's DNA. The first successful case of genetic engineering occurred in 1973 when Herbert Boyer and Stanley Cohen were able to transfer a gene with antibiotic resistance to a bacterium. === Science === There are three main techniques used in genetic engineering: The plasmid method, the vector method and the biolistic method. ==== Plasmid method ==== This technique is used mainly for microorganisms such as bacteria. Through this method, DNA molecules called plasmids are extracted from bacteria and placed in a lab where restriction enzymes break them down. As the enzymes do this, some develop a rough edge that resembles that of a staircase which is considered 'sticky' and capable of reconnecting. These 'sticky' molecules are inserted into another bacteria where they will connect to the DNA rings with the altered genetic material. ==== Vector method ==== The vector method is considered a more precise technique than the plasmid method as it involves the transfer of a specific gene instead of a whole sequence. In the vector method, a specific gene from a DNA strand is isolated through restriction enzymes in a laboratory and is inserted into a vector. Once the vector accepts the genetic code, it is inserted into the host cell where the DNA will be transferred. ==== Biolistic method ==== The biolistic method is typically used to alter the genetic material of plants. This method embeds the desired DNA with a metallic particle such as gold or tungsten in a high speed gun. The particle is then bombarded into the plant. Due to the high velocities and the vacuum generated during bombardment, the particle is able to penetrate the cell wall and inserts the new DNA into the cell. === Applications === Genetic engineering has many uses in the fields of medicine, research and agriculture. In the medical field, genetically modified bacteria are used to produce drugs such as insulin, human growth hormones and vaccines. In research, scientists genetically modify organisms to observe physical and behavioral changes to understand the function of specific genes. In agriculture, genetic engineering is extremely important as it is used by farmers to grow crops that are resistant to herbicides and to insects such as BTCorn. == Bionics == Bionics is a medical engineering field and a branch of biorobotics consisting of electrical and mechanical systems that imitate biological systems, such as prosthetics and hearing aids. It's a portmanteau that combines biology and electronics. === History === The history of bionics goes as far back in time as ancient Egypt. A prosthetic toe made out of wood and leather was found on the foot of a mummy. The time period of the mummy corpse was estimated to be from around the fifteenth century B.C. Bionics can also be witnessed in ancient Greece and Rome. Prosthetic legs and arms were made for amputee soldiers. In the early 16th century, a French military surgeon by the name of Ambroise Pare became a pioneer in the field of bionics. He was known for making various types of upper and lower prosthetics. One of his most famous prosthetics, Le Petit Lorrain, was a mechanical hand operated by catches and springs. During the early 19th century, Alessandro Volta further progressed bionics. He set the foundation for the creation of hearing aids with his experiments. He found that electrical stimulation could restore hearing by inserting an electrical implant to the saccular nerve of a patient's ear. In 1945, the National Academy of Sciences created the Artificial Limb Program, which focused on improving prosthetics since there were a large number of World War II amputee soldiers. Since this creation, prosthetic materials, computer design methods, and surgical procedures have improved, creating modern-day bionics. === Science === ==== Prosthetics ==== The important components that make up modern-day prosthetics are the pylon, the socket, and the suspension system. The pylon is the internal frame of the prosthetic that is made up of metal rods or carbon-fiber composites. The socket is the part of the prosthetic that connects the prosthetic to the person's missing limb. The socket consists of a soft liner that makes the fit comfortable, but also snug enough to stay on the limb. The suspension system is important in keeping the prosthetic on the limb. The suspension system is usually a harness system made up of straps, belts or sleeves that are used to keep the limb attached. The operation of a prosthetic could be designed in various ways. The prosthetic could be body-powered, externally-powered, or myoelectrically powered. Body-powered prosthetics consist of cables attached to a strap or harness, which is placed on the person's functional shoulder, allowing the person to manipulate and control the prosthetic as he or she deems fit. Externally-powered prosthetics consist of motors to power the prosthetic and buttons and switches to control the prosthetic. Myoelectrically powered prosthetics are new, advanced forms of prosthetics where electrodes are placed on the muscles above the limb. The electrodes will detect the muscle contractions and send electrical signals to the prosthetic to move the prosthetic. The downside to this type of prosthetic is that if the sensors are not placed correctly on the limb then the electrical impulses will fail to move the prosthetic. TrueLimb is a specific brand of prosthetics that uses myoelectrical sensors which enable a person to have control of their bionic limb. ==== Hearing aids ==== Four major components make up the hearing aid: the microphone, the amplifier, the receiver, and the battery. The microphone takes in outside sound, turns that sound to electrical signals, and sends those signals to the amplifier. The amplifier increases the sound and sends that sound to the receiver. The receiver changes the electrical signal back into sound and sends the sound into the ear. Hair cells in the ear will sense the vibrations from the sound, convert the vibrations into nerve signals, and send it to the brain so

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  BiP (software)

  BiP is a freeware instant messaging application developed by Lifecell Ventures Cooperatief U.A., a subsidiary of Turkcell incorporated in the Netherlands. It allows users to send text messages, voice messages and video calling, and it can be downloaded from the App Store, Google Play, and Huawei AppGallery. BiP has over 53 million users worldwide, and was first released in 2013. == Functions == BiP is a secure, and free communication platform. BiP allows making video and audio calls, allows sharing images, videos and location. BiP includes instant translations to 106 languages and exchange rates. President Erdoğan's Communications Office opposed WhatsApp's enforcement of its updated privacy policy and announced that Erdoğan left WhatsApp and opened an account in Telegram and BiP. The Turkish Ministry of National Defense has announced that it will move information groups to BiP for the same reason. == Others == Banglalink announced a BiP messenger partnership in Bangladesh The Communications Office of President Erdoğan opposed WhatsApp's enforcement of its updated privacy policy and announced that Erdoğan left WhatsApp and opened an account in Telegram and BiP. The Turkish Ministry of National Defense has announced that it will move information groups to BiP for the same reason. The CEO of BiP is Burak Akinci. The number of downloads of the app is 80 million globally.

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