Best AI Writing Tools

Best AI Writing Tools — hands-on reviews, top picks, pricing, pros and cons and a practical how-to guide on Aizhi.

  • Unit of work

    Unit of work

    A unit of work is a behavioral pattern in software development. Martin Fowler has defined it as everything one does during a business transaction which can affect the database. When the unit of work is finished, it will provide everything that needs to be done to change the database as a result of the work. A unit of work encapsulates one or more code repositories[de] and a list of actions to be performed which are necessary for the successful implementation of self-contained and consistent data change. A unit of work is also responsible for handling concurrency issues, and can be used for transactions and stability patterns.[de]

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  • Cleverpath AION Business Rules Expert

    Cleverpath AION Business Rules Expert

    Cleverpath AION Business Rules Expert (formerly Platinum AIONDS, and before that Trinzic AIONDS, and originally Aion) is an expert system and Business rules engine owned by Computer Associates by 2000. == History == The product was created around 1986 as "Aion" by the Aion company. In its initial release Aion was multi-platform and continues to be deliverable to the PC, Unixs, and Mainframe computer's. In addition it ties in seamlessly with a variety of databases including Oracle, Microsoft SQL Server, and ODBC. Aion was founded by Harry Reinstein, Larry Cohn, Garry Hallee, Scott Grinis, and others. From Scott Grinis's bio: Scott founded Aion, a company that developed expert systems and whose advanced inference engine and object technology were used by financial services and insurance firms to develop risk-scoring and underwriting applications. Harry Reinstein was quoted as saying: “Our biggest competitor was not AICorp, it was COBOL” Trinzic owned AION by 1993. A reference in a 1993 announcement indicates that Trinzic's formation was the result of a merger (paraphased): Trinzic set three development initiatives shortly after its formation from the merger of Aion Corp. and AICorp. The other initiatives -- adding SQL extensions to Aion/DS and evaluating the unbundling of some of that product's object-oriented programming capabilities -- are still active. Writing in 1993 Judith Hodges and Deborah Melewski give the date for the merger: Two rival artificial intelligence software vendors -- AICorp, Inc. and Aion Corp. -- merged in September 1992 to form Trinzic Corp. As part of the merger, redundant jobs were eliminated (20% of the combined work force), leaving a total work force of 245 employees worldwide. The new firm also boasted a combined installed base of more than 1,200 sites representing more than 10,000 software licenses. Although in the merger, technically AICorp bought Aion, as AICorp was a public company and Aion was still private, the reality was that Aion's leadership and technology subsumed AICorp's. Jim Gagnard, the CEO of Aion, became CEO of Trinzic and AICorp's flagship product, KBMS, was discontinued, while the Aion Development System continued to be enhanced and KBMS customers were assisted in converting to AIONDS, under the continued technical leadership of Garry Hallee and Scott Grinis. On August 1, 1994 Trinzic released version 6.4 of AIONDS saying, in part: Trinzic Corp., Palo Alto, Calif., has unveiled The Aion Development System (AionDS) Version 6.4, an upgrade to the company's development environment for building business process automation applications. Version 6.4 provides a visual development environment for Microsoft Windows or OS/2 PM applications using business rules. Trinzic was acquired by PLATINUM Technologies in 1995 which retained at least some of Trinzic's acquisitions Platinum Technologies was acquired by Computer Associates in 1999. CA changed the system's name to CA Aion Business Rules Expert" on or before 2009. It is currently (June 2011) at Release 11 on a wide range of supported platforms. == Applications using Aion == Aion has been used in a variety of industries including Energy, Insurance, Military, Aviation, and Banking. At one point an Aion expert system application written by Covia, LLC existed to do airport gate assignment. Colossus, a computer program, developed by Computer Sciences Corporation is the insurance industry’s leading expert system for assisting adjusters in the evaluation of bodily injury claims (aka "pain and suffering"). Colossus helps adjusters reduce variance in payouts on similar bodily injury claims through objective use of industry standard rules.

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  • Retrieval-based Voice Conversion

    Retrieval-based Voice Conversion

    Retrieval-based Voice Conversion (RVC) is an open source voice conversion AI algorithm that enables realistic speech-to-speech transformations, accurately preserving the intonation and audio characteristics of the original speaker. == Overview == In contrast to text-to-speech systems such as ElevenLabs, RVC differs by providing speech-to-speech outputs instead. It maintains the modulation, timbre and vocal attributes of the original speaker, making it suitable for applications where emotional tone is crucial. The algorithm enables both pre-processed and real-time voice conversion with low latency. This real-time capability marks a significant advancement over previous AI voice conversion technologies, such as So-vits SVC. Its speed and accuracy have led many to note that its generated voices sound near-indistinguishable from "real life", provided that sufficient computational specifications and resources (e.g., a powerful GPU and ample RAM) are available when running it locally and that a high-quality voice model is used. == Technical foundation == Retrieval-based Voice Conversion (RVC) utilizes a hybrid approach that integrates feature extraction with retrieval-based synthesis. Instead of directly mapping source speaker features to the target speaker using statistical models, RVC retrieves relevant segments from a target speech database, aiming to enhance the naturalness and speaker fidelity of the converted speech. At a high level, the RVC system typically comprises three main components: (1) a content feature extractor, such as a phonetic posteriorgram (PPG) encoder or self-supervised models like HuBERT; (2) a vector retrieval module that searches a target voice database for the most similar speech units; and (3) a vocoder or neural decoder that synthesizes waveform output from the retrieved representations. The retrieval-based paradigm aims to mitigate the oversmoothing effect commonly observed in fully neural sequence-to-sequence models, potentially leading to more expressive and natural-sounding speech. Furthermore, with the incorporation of high-dimensional embeddings and k-nearest-neighbor search algorithms, the model can perform efficient matching across large-scale databases without significant computational overhead. Recent RVC frameworks have incorporated adversarial learning strategies and GAN-based vocoders, such as HiFi-GAN, to enhance synthesis quality. These integrations have been shown to produce clearer harmonics and reduce reconstruction errors. == Research developments == Research on RVC has recently explored the use of self-supervised learning (SSL) encoders such as wav2vec 2.0 and HuBERT to replace hand-engineered features like MFCCs. These encoders improve content preservation, especially when source and target speakers have dissimilar speaking styles or accents. Moreover, modern RVC models leverage vector quantization methods to discretize the acoustic space, improving both synthesis accuracy and generalization across unseen speakers. For example, retrieval-augmented VQ models can condition the synthesis stage on quantized speech tokens, which enhances controllability and style transfer. Despite its strengths, RVC still faces limitations related to database coverage, especially in real-time or few-shot settings. Inadequate diversity in the target voice corpus may lead to suboptimal retrieval or unnatural prosody. These advances demonstrate the viability of RVC as a strong alternative to conventional deep learning VC systems, balancing both flexibility and efficiency in diverse voice synthesis applications. == Training process == The training pipeline for retrieval-based voice conversion typically includes a preprocessing step where the target speaker's dataset is segmented and normalized. A pitch extractor such as librosa or DDSP-DDC may be used to obtain fundamental frequency (F0) features. During training, the model learns to map content features from the source speaker to the acoustic representation of the target speaker while maintaining pitch and prosody. The training objective often combines reconstruction loss with feature consistency loss across intermediate layers, and may incorporate cycle consistency loss to preserve speaker identity. Fine-tuning on small datasets is feasible due to the use of pre-trained models, particularly for the SSL encoder and content extractor components. This approach allows transfer learning to be applied effectively, enabling the model to converge faster and generalize better to unseen inputs. Most open implementations support batch training, gradient accumulation, and mixed-precision acceleration (e.g., FP16), especially when utilizing NVIDIA CUDA-enabled GPUs. == Real-time deployment == RVC systems can be deployed in real-time scenarios through WebUI interfaces and streaming audio frameworks. Optimizations include converting the inference graph to ONNX or TensorRT formats, reducing latency. Audio buffers are typically processed in chunks of 0.2–0.5 seconds to ensure minimal delay and seamless conversion. Cross-platform compatibility with tools such as OBS Studio and Voicemeeter enables integration into live streaming, video production, or virtual avatar environments. == Applications and concerns == The technology enables voice changing and mimicry, allowing users to create accurate models of others using only a negligible amount of minutes of clear audio samples. These voice models can be saved as .pth (PyTorch) files. While this capability facilitates numerous creative applications, it has also raised concerns about potential misuse as deepfake software for identity theft and malicious impersonation through voice calls. == Ethical and legal considerations == As with other deep generative models, the rise of RVC technology has led to increasing debate about copyright, consent, and authorship. While some jurisdictions may allow parody or fair use in creative contexts, impersonating living individuals without permission may infringe upon privacy and likeness rights. As a result, some platforms have begun issuing takedown notices against AI-generated voice content that closely mimics celebrities or musicians. === In pop culture === RVC inference has been used to create realistic depictions of song covers, such as replacing original vocals with characters like Twilight Sparkle and Mordecai to have them sing duets of popular music like "Airplanes" and "Somebody That I Used to Know." These AI-generated covers, which can sound strikingly similar to the voice imitated, have gained popularity on platforms like YouTube as humorous memes.

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  • Responsible AI Safety and Education Act

    Responsible AI Safety and Education Act

    The Responsible AI Safety and Education Act (RAISE Act) is a New York State law that imposes transparency, safety, and reporting requirements on developers of large frontier artificial intelligence models. The law was signed by Governor Kathy Hochul on December 19, 2025. It was sponsored by State Senator Andrew Gounardes and Assemblymember Alex Bores. The RAISE Act is the second U.S. state law to regulate frontier AI model developers, following California's Transparency in Frontier Artificial Intelligence Act (TFAIA), which was signed in September 2025. Hochul signed the bill on the condition that the legislature would pass chapter amendments to bring the law closer to the California model. The amending bills (A9449/S8828) were introduced in January 2026; as of February 2026 they remain in committee, though the Governor's office and legal commentators treat the agreed-upon amendments as representing the final form of the law. == Provisions == The following describes the RAISE Act as it is expected to operate after the agreed-upon chapter amendments take effect. The law is expected to take effect on January 1, 2027. === Scope === The law applies to "large frontier developers," defined as companies with annual revenues exceeding $500 million that develop "frontier models," which are foundation models trained using more than 1026 floating-point operations (FLOPs). The version passed by the legislature in June 2025 had instead defined large developers based on having spent over $100 million in aggregate compute costs, and also included a provision prohibiting deployment of frontier models posing "unreasonable risk of critical harm"; both were removed as part of the negotiations between Hochul and the legislature. Accredited colleges and universities engaged in academic research are exempt, as is the state's Empire AI consortium. === Safety and transparency framework === Large frontier developers must write, implement, and publicly publish a "frontier AI framework" describing how they assess and mitigate catastrophic risks, secure unreleased model weights against unauthorized access, use third-party evaluators, govern internal use of frontier models, and respond to safety incidents. The framework must describe these measures "in detail," a requirement that goes beyond the California TFAIA's requirement to describe a developer's "approach." The framework must be reviewed at least annually, and material modifications must be published with justification within 30 days. Before or concurrently with deploying a new or substantially modified frontier model, developers must publish a transparency report including the model's release date, supported languages and output modalities, intended uses, and any restrictions on use. Large frontier developers must additionally include summaries of catastrophic risk assessments and the extent of third-party involvement. === Catastrophic risk and incident reporting === The law defines "catastrophic risk" as a foreseeable and material risk that a frontier model will contribute to the death of or serious injury to more than 50 people, or more than $1 billion in property damage, arising from a frontier model providing expert-level assistance in creating chemical, biological, radiological, or nuclear weapons; engaging in cyberattacks or conduct equivalent to crimes such as murder, assault, or theft without meaningful human oversight; or evading the control of its developer or user. Loss of equity value is explicitly excluded from the definition of property damage. "Critical safety incidents" include unauthorized access to model weights resulting in death or injury, materialization of a catastrophic risk, loss of control of a frontier model causing death or injury, and a model using deceptive techniques to subvert developer controls outside of an evaluation context in a manner that increases catastrophic risk. Frontier developers must report critical safety incidents within 72 hours, or within 24 hours if the incident poses an imminent risk of death or serious physical injury. === Enforcement === The chapter amendments establish a new office within the New York State Department of Financial Services to oversee compliance, receive incident reports, and publish annual reports on AI safety beginning in 2028. Large frontier developers must file disclosure statements with this office and pay pro rata assessments to fund its operations. The New York Attorney General may bring civil actions, with penalties of up to $1 million for a first violation and $3 million for subsequent violations. The version passed by the legislature in June 2025 had set penalties at up to $10 million and $30 million respectively. The law does not create a private right of action. == Legislative history == The bill was introduced in the Assembly on March 5, 2025, by Assemblymember Alex Bores, and in the Senate on March 27, 2025, by Senator Andrew Gounardes. After a series of amendments, the legislature passed the bill in June 2025. Governor Hochul did not immediately sign the bill, using nearly all the time available under New York law before acting; had she not signed by the end of 2025, the bill would have been pocket vetoed. The tech industry lobbied against the bill during this period, and Hochul initially proposed a near-complete rewrite modeled on California's TFAIA. Legislators resisted the extent of the changes, and the two sides ultimately agreed on a version that used the California law as a base but preserved several provisions that went beyond it, including the 72-hour incident reporting timeline and the creation of a dedicated enforcement office. Hochul signed the original bill (S6953-B/A6453-B) on December 19, 2025, with the legislature committing to pass chapter amendments formalizing the agreed changes in the January 2026 session. The amending bills (A9449 in the Assembly, S8828 in the Senate) were introduced on January 6 and January 8, 2026. OpenAI and Anthropic expressed support for the law. Anthropic's head of external affairs Sarah Heck said the two state laws "should inspire Congress to build on them." The super PAC network Leading the Future, backed by Andreessen Horowitz and OpenAI president Greg Brockman, subsequently announced plans to challenge Bores in a future election. == Federal preemption debate == Hochul signed the RAISE Act eight days after President Donald Trump issued an executive order on December 11, 2025, directing the Department of Justice to challenge state AI laws deemed to conflict with a "minimally burdensome" national AI policy. On January 9, 2026, the Department of Justice announced the establishment of an AI Litigation Task Force as called for by the executive order. The executive order also threatened states with loss of certain federal broadband funding if their AI laws were found to be onerous. Legal commentators have noted several potential avenues for federal challenge, including arguments that the law constitutes compelled speech, violates the dormant Commerce Clause by creating a patchwork of state regulations, or is preempted by federal AI policy. == Comparison with California's TFAIA == The RAISE Act was designed to align with California's Transparency in Frontier Artificial Intelligence Act, signed on September 29, 2025. Both laws use the same 1026 FLOP threshold to define frontier models and the same $500 million revenue threshold to define large developers. Both require public safety frameworks, transparency reports, and incident reporting. The RAISE Act's 72-hour incident reporting window is stricter than the TFAIA's 15-day window, though both require faster reporting for incidents posing imminent physical risk (24 hours under the RAISE Act, immediate under the TFAIA). The RAISE Act establishes a dedicated enforcement office within the Department of Financial Services, whereas California routes reports through the Office of Emergency Services. The RAISE Act requires developers to describe their safety measures "in detail" and how they "handle" various risks, whereas the TFAIA requires developers to describe their "approach."

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  • DryvIQ

    DryvIQ

    DryvIQ is a software application that enables businesses to migrate on-site system files and associated data across storage and content management platforms, as well as create synchronized hybrid storage systems. == History == Before it was DryvIQ, the software SkySync was released in 2013 by Ann Arbor, Michigan based company, Portal Architects, Inc. The company created SkySync, a back-end, administrative application designed to transfer content across storage platforms, after abandoning 18 months of development on a desktop application called SkyBrary in 2011. Between 2014 and 2015, Portal Architects established partnerships with the following companies: Autodesk, Box, Dropbox, Egnyte, EMC, Google, Syncplicity, Huddle, IBM, Microsoft, OpenText, Oracle, Citrix ShareFile, Hightail and Internet2. SkySync (currently DryvIQ) was named a "Cool Vendor in Content Management" by Gartner in 2015. In 2022, SkySync changed its name to DryvIQ, which is now what the company is currently known as. == Overview == DryvIQ is a software application that syncs, migrates or backs up files including their associated properties, metadata, versions, user accounts and permissions across on-premises and Cloud-based storage platforms. The software deploys on a server, virtual machine or within Microsoft Azure, Amazon Web Services or other cloud computing services.

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  • General-Purpose AI Code of Practice

    General-Purpose AI Code of Practice

    The General-Purpose AI Code of Practice (GPAI CoP) is a compliance tool released by the European Commission on 10 July 2025 to support compliance with the European Union Artificial Intelligence Act (AI Act). It provides operational guidance for providers of general-purpose AI models, particularly in relation to Articles 53 and 55 of the AI Act, which entered into application on 2 August 2025. The Code is organised into three chapters (Transparency, Copyright, and Safety and Security) and outlines how providers can meet the Act's relevant obligations. Although non-binding, providers can rely on adherence to the Code, meaning that EU regulators will assume that providers following the Code meet the corresponding legal requirements of the AI Act. As such, signatories to the Code will benefit from reduced administrative burdens and increased legal certainty compared to providers that prove compliance in other ways. While adherence to the Code is voluntary, compliance with the AI Act is not. == Background == The EU AI Act, adopted in 2024, established a risk-based regulatory regime for artificial intelligence in the European Union. The rationale for the GPAI CoP stems from Article 56 of the AI Act, which empowers the EU AI Office to develop a voluntary rulebook to guide how AI model providers can meet their legal obligations – specifically those found in Articles 53 and 55. Under Articles 53 and 55, developers of general-purpose AI models whose training compute exceeds 1023 floating-point operations (FLOPs) and that are placed on the EU market must meet transparency obligations and put in place a policy for EU copyright law. Models trained with more than 1025 FLOPs are classified as presenting systemic risk and are subject to enhanced safety requirements. The Commission may also designate a model as presenting systemic risk if it has equivalent impact or capabilities (Annex XIII criteria), even below that compute figure. Because the AI Act is relatively vague on how model providers should implement these requirements, the Code is meant to help by detailing processes and practices for compliance. == Drafting process == The development of the GPAI CoP was drawn up by 13 independent experts and involved four thematic working groups: Transparency & Copyright, Risk assessment for systemic risk, Technical risk mitigation for systemic risk, and Governance risk mitigation for systemic risk. Each group was coordinated by the European Union Artificial Intelligence Office (EU AI Office), drawing on contributions from nearly 1,000 stakeholders, including AI developers, academics, civil society organisations, national authorities, and international observers. The Code underwent three earlier iterations in November 2024, December 2024, and March 2025, before the final version was published on 10 July 2025, more than two months later than initially planned. The GPAI CoP will likely be updated continuously by the EU AI Office, alongside other tools such as the training data summary template. == Signatories == Among U.S.-based technology companies, Amazon, Anthropic, Google, IBM, Microsoft, and OpenAI have signed the GPAI CoP. xAI, founded by Elon Musk, has signed only one of the three chapters, namely the safety and security chapter. Prominent European AI companies that have signed include Aleph Alpha and Mistral AI. The European Commission maintains an updated list of signatories. As of January 2026, Meta is the most notable company that has declined to sign the Code. Major Chinese AI companies, such as Alibaba, Baidu or Deepseek, have also not signed. Providers that do not sign the GPAI CoP will still have to adhere to the binding requirements of the EU AI Act. The European Commission has indicated that it may take tougher action against companies that didn't sign the Code. == Transparency and Copyright chapters == The first two chapters of the GPAI CoP address transparency and copyright compliance and apply to all GPAI providers. They offer a way to demonstrate compliance with their obligations under Article 53 AI Act. The Transparency chapter addresses the documentation of a model's capabilities, limitations, and points of contact, and expects providers to make key documentation available to downstream providers. Signatories must also publish summaries of the content used to train their models. In the Copyright chapter, Signatories commit to follow a policy that aligns with EU copyright law. For example, they commit to mitigating the risk of copyright-infringing output. == Safety and Security chapter == The Safety and Security chapter is the most extensive chapter of the Code, and it applies to GPAI models with systemic risk, meaning it's only relevant to the small number of providers of the most advanced models. It specifies how Signatories commit to meeting Article 55(1) obligations to: Conduct model evaluations to identify systemic risks Assess and mitigate those risks Track and report serious incidents Ensure the cyber and physical security of their models The chapter outlines a comprehensive risk management process that must be applied before major deployment decisions, such as releasing a new systemic-risk GPAI model in the EU market, or substantially updating an existing one. Signatories commit to identifying systemic risks of their model, analysing and evaluating them, determining whether risk levels are acceptable, and implementing mitigation measures if necessary. This process should be repeated until models achieve an acceptable level of risk across all identified risks. === Risk identification === Signatories commit to analysing and evaluating at least four “specified” categories of systemic risk: CBRN (chemical, biological, radiological, and nuclear) Loss of control Cyber offence Harmful manipulation They are also expected to identify other systemic risks to public health, safety, and fundamental rights. The Code instructs providers to consider model capabilities, propensities, and affordances in this identification. Signatories commit to developing risk scenarios illustrating how identified risks could materialise in real-world conditions. === Risk analysis and risk evaluation === After identifying potential systemic risks, Signatories commit to analysing and evaluating the risks in order to determine whether they are acceptable or not, drawing on scientific literature, training data analysis, incident databases, expert consultation, and other sources. They also commit to conducting state-of-the-art model evaluations such as benchmarking, red teaming, and human uplift studies, targeting each risk. The risk analysis process is interconnected: insights from risk modelling should inform model evaluation design, while post-market monitoring should feed back into ongoing analysis. Signatories commit to ultimately estimating the likelihood and severity of each systemic risk. ==== Independent external model evaluations ==== Appendix 3.5 of the Safety and Security chapter requires signatories to ensure that independent external evaluators conduct model evaluations. Signatories may claim an exemption from this requirement only if they can demonstrate that their model is “similarly safe” to another model that has already been shown to comply with the Code, or if they are unable to appoint an appropriately qualified evaluator. The determination of “similarly safe” is based on comparable performance on benchmarks and the similarity of other model characteristics, such as their architecture. The CoP acknowledges that this kind of information is typically available only for models by the same provider, or potentially for open-weights or open-source models. === Risk acceptance criteria === The Code requires providers to compare estimated risks against predefined acceptance criteria, which must be measurable, based on model capabilities, and defined preemptively. While providers get to determine the level of risk they deem acceptable themselves, the pre-defined criteria and acceptance thresholds ensure providers cannot adjust their level of tolerance flexibly ahead of deployment decisions. Only if all risks are below acceptable levels should a model be deployed. === Continuous risk management and governance === The Code mandates ongoing risk management throughout the model lifecycle, including light-touch evaluations, continuous mitigation, post-market monitoring, and incident tracking and reporting. It further requires organisational governance structures assigning responsibility for risk management and expects providers to promote a “healthy risk culture,” including informing employees about the whistleblower protection policy, allowing internal challenges of decisions concerning systemic risk management, and committing to not retaliating against employees who disclose concerns about systemic risks to oversight authorities. === Documentation and transparency === Signatories commit to creating two types of documentation: Safety and Security Frame

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  • Clinical quality management system

    Clinical quality management system

    Clinical quality management systems (CQMS) are systems used in the life sciences sector (primarily in the pharmaceutical, biologics and medical device industries) designed to manage quality management best practices throughout clinical research and clinical study management. A CQMS system is designed to manage all of the documents, activities, tasks, processes, quality events, relationships, audits and training that must be administered and controlled throughout the life of a clinical trial. The premise of a CQMS is to bring together the activities led by two sectors of clinical research, Clinical Quality and Clinical Operations, to facilitate cross-functional activities to improve efficiencies and transparency and to encourage the use of risk mitigation and risk management practices at the clinical study level. Based on the principles of quality management systems (QMS) which are used in many industries to create a framework for defining and delivering quality outcomes, managing risk, and continual improvement. Many guidelines and governance bodies have been established to ensure a common approach within a given industry to a set of parameters used to identify the minimally acceptable standard for that industry. The pharmaceutical industry is no exception, with several trade groups (e.g. PhRMA, EFPIA, RQA, etc.) coming together to enhance collaboration. However, as noted by the Academy of Medical Sciences, there are increasingly complex and bureaucratic legal and ethical frameworks that innovators must work within to develop new medicines for patients. The historical pharmaceutical QMS applies primarily to good manufacturing practice as described in existing ISO (International Organization for Standardization) and ICH (International Committee on Harmonization) guidelines. "Good Manufacturing Practices (GMP) relate to quality control and quality assurance enabling companies in the pharmaceutical sector to minimize or eliminate instances of contamination, mix-ups, and errors. This in turn, protects the customer from purchasing a product which is ineffective or even dangerous." These standards have historically been applied to the manufacturing environment, appropriate to how they have been written. However, according to FDA as well as other regulatory bodies, "Implementation of ICH Q10 throughout the product lifecycle should facilitate innovation and continual improvement", implying that the same standards that apply to the manufacturing environment should also be applied to the clinical research space, earlier in the lifecycle of an investigational or marketed product. Accordingly, a CQMS is any system developed to apply these principles to clinical operations within an organization.

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  • Ballie

    Ballie

    Ballie is an AI robot created by Samsung to be released in 2026. It is an autonomous robot which has the ability to control smart home devices. Ballie can text, send pictures and follow commands through SmartThings. It can also show workout information shared from a Galaxy Watch. Ballie can make video calls and welcome you home. == History == It was first unveiled at Samsung's CES event in CES 2020, and later updated the design in CES 2024, and will be later released in 2026. == Design ==

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  • Cygwin

    Cygwin

    Cygwin ( SIG-win) is a free and open-source Unix-like environment and command-line interface (CLI) for Microsoft Windows. The project also provides a software repository containing open-source packages. Cygwin allows source code for Unix-like operating systems to be compiled and run on Windows. Cygwin provides native integration of Windows-based applications. The terminal emulator mintty is the default command-line interface provided to interact with the environment. The Cygwin installation directory layout mimics the root file system of Unix-like systems, with directories such as /bin, /home, /etc, /usr, and /var. Cygwin is released under the GNU Lesser General Public License version 3. It was originally developed by Cygnus Solutions, which was later acquired by Red Hat (now part of IBM), to port the GNU toolchain to Win32, including the GNU Compiler Suite. Rather than rewrite the tools to use the Win32 runtime environment, Cygwin implemented a POSIX-compatible environment in the form of a DLL. The brand motto is "Get that Linux feeling – on Windows", although Cygwin doesn't have Linux in it. == History == Cygwin began in 1995 as a project of Steve Chamberlain, a Cygnus engineer who observed that Windows NT and 95 used COFF as their object file format, and that GNU already included support for x86 and COFF, and the C library newlib. He thought that it would be possible to retarget GCC and produce a cross compiler generating executables that could run on Windows. A prototype was later developed. Chamberlain bootstrapped the compiler on a Windows system, to emulate Unix to let the GNU configure shell script run. Initially, Cygwin was called Cygwin32. When Microsoft registered the trademark Win32, the "32" was dropped to simply become Cygwin. In 1999, Cygnus offered Cygwin 1.0 as a commercial product. Subsequent versions have not been released, instead relying on continued open source releases. Geoffrey Noer was the project lead from 1996 to 1999. Christopher Faylor was lead from 1999 to 2004; he left Red Hat and became co-lead with Corinna Vinschen. Corinna Vinschen has been the project lead from mid-2014 to date (as of September, 2024). From June 23, 2016, the Cygwin library version 2.5.2 was licensed under the GNU Lesser General Public License (LGPL) version 3. == Description == Cygwin is provided in two versions: the full 64-bit version and a stripped-down 32-bit version, whose final version was released in 2022. Cygwin consists of a library that implements the POSIX system call API in terms of Windows system calls to enable the running of a large number of application programs equivalent to those on Unix systems, and a GNU development toolchain (including GCC and GDB). Programmers have ported the X Window System, K Desktop Environment 3, GNOME, Apache, and TeX. Cygwin permits installing inetd, syslogd, sshd, Apache, and other daemons as standard Windows services. Cygwin programs have full access to the Windows API and other Windows libraries. Cygwin programs are installed by running Cygwin's "setup" program, which downloads them from repositories on the Internet. The Cygwin API library is licensed under the GNU Lesser General Public License version 3 (or later), with an exception to allow linking to any free and open-source software whose license conforms to the Open Source Definition. Cygwin consists of two parts: A dynamic-link library in the form of a C standard library that acts as a compatibility layer for the POSIX API and A collection of software tools and applications that provide a Unix-like look and feel. Cygwin supports POSIX symbolic links, representing them as plain-text files with the system attribute set. Cygwin 1.5 represented them as Windows Explorer shortcuts, but this was changed for reasons of performance and POSIX correctness. Cygwin also recognises NTFS junction points and symbolic links and treats them as POSIX symbolic links, but it does not create them. The POSIX API for handling access control lists (ACLs) is supported. === Technical details === A Cygwin-specific version of the Unix mount command allows mounting Windows paths as "filesystems" in the Unix file space. Initial mount points can be configured in /etc/fstab, which has a format very similar to Unix systems, except that Windows paths appear in place of devices. Filesystems can be mounted in binary mode (by default), or in text mode, which enables automatic conversion between LF and CRLF endings (which only affects programs that open files without explicitly specifying text or binary mode). Cygwin 1.7 introduced comprehensive support for POSIX locales, and the UTF-8 Unicode encoding became the default. The fork system call for duplicating a process is fully implemented, but the copy-on-write optimization strategy could not be used. Cygwin's default user interface is the bash shell running in the mintty terminal emulator. The DLL also implements pseudo terminal (pty) devices, and Cygwin ships with a number of terminal emulators that are based on them, including rxvt/urxvt and xterm. The version of GCC that comes with Cygwin has various extensions for creating Windows DLLs, such as specifying whether a program is a windowing or console-mode program. Support for compiling programs that do not require the POSIX compatibility layer provided by the Cygwin DLL used to be included in the default GCC, but as of 2014, it is provided by cross-compilers contributed by the MinGW-w64 project. == Software packages == Cygwin's base package selection is approximately 100MB, containing the bash (interactive user) and dash (installation) shells and the core file and text manipulation utilities. Additional packages are available as optional installs from within the Cygwin "setup" program and package manager ("setup-x86_64.exe" – 64 bit). The Cygwin Ports project provided additional packages that were not available in the Cygwin distribution itself. Examples included GNOME, K Desktop Environment 3, MySQL database, and the PHP scripting language. Most ports have been adopted by volunteer maintainers as Cygwin packages, and Cygwin Ports are no longer maintained. Cygwin ships with GTK+ and Qt. The Cygwin/X project allows graphical Unix programs to display their user interfaces on the Windows desktop for both local and remote programs.

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  • Mojo (programming language)

    Mojo (programming language)

    Mojo is an in-development proprietary programming language based on Python available for Linux and macOS. Mojo aims to combine the usability of a high-level programming language, specifically Python, with the performance of a system programming language such as C++, Rust, and Zig. As of October 2025, the Mojo compiler is closed source with an open source standard library. Modular, the company behind Mojo, has stated an intent to open source the Mojo language, committing to open-source Mojo in "fall 2026". Mojo builds on the Multi-Level Intermediate Representation (MLIR) compiler software framework, instead of directly on the lower level LLVM compiler framework like many languages such as Julia, Swift, C++, and Rust. MLIR is a newer compiler framework that allows Mojo to exploit higher level compiler passes unavailable in LLVM alone, and allows Mojo to compile down and target more than only central processing units (CPUs), including producing code that can run on graphics processing units (GPUs), Tensor Processing Units (TPUs), application-specific integrated circuits (ASICs) and other accelerators. It can also often more effectively use certain types of CPU optimizations directly, like single instruction, multiple data (SIMD) with minor intervention by a developer, as occurs in many other languages. According to Jeremy Howard of fast.ai, Mojo can be seen as "syntax sugar for MLIR" and for that reason Mojo is well optimized for applications like artificial intelligence (AI). == Origin and development history == The Mojo programming language was created by Modular Inc, which was founded by Chris Lattner, the original architect of the Swift programming language and LLVM, and Tim Davis, a former Google employee. The intention behind Mojo is to bridge the gap between Python’s ease of use and the fast performance required for cutting-edge AI applications. According to public change logs, Mojo development goes back to 2022. In May 2023, the first publicly testable version was made available online via a hosted playground. By September 2023 Mojo was available for local download for Linux and by October 2023 it was also made available for download on Apple's macOS. In March 2024, Modular open sourced the Mojo standard library and started accepting community contributions under the Apache 2.0 license. == Features == Mojo was created for an easy transition from Python. The language has syntax similar to Python's, with inferred static typing, and allows users to import Python modules. It uses LLVM and MLIR as its compilation backend. The language also intends to add a foreign function interface to call C/C++ and Python code. The language is not source-compatible with Python 3, only providing a subset of its syntax, e.g. missing the global keyword, list and dictionary comprehensions, and support for classes. Further, Mojo also adds features that enable performant low-level programming: fn for creating typed, compiled functions and "struct" for memory-optimized alternatives to classes. Mojo structs support methods, fields, operator overloading, and decorators. The language also provides a borrow checker, an influence from Rust. Mojo def functions use value semantics by default (functions receive a copy of all arguments and any modifications are not visible outside the function), while Python functions use reference semantics (functions receive a reference on their arguments and any modification of a mutable argument inside the function is visible outside). The language is not currently open source, but it is planned to be made open source in the future. Modular has since committed to open-sourcing the Mojo language in "fall 2026". == Programming examples == In Mojo, functions can be declared using both fn (for performant functions) or def (for Python compatibility). Basic arithmetic operations in Mojo with a def function: and with an fn function: The manner in which Mojo employs var and let for mutable and immutable variable declarations respectively mirrors the syntax found in Swift. In Swift, var is used for mutable variables, while let is designated for constants or immutable variables. Variable declaration and usage in Mojo:

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  • Script theory

    Script theory

    Script theory is a psychological theory which posits that human behaviour largely falls into patterns called scripts because they function the way a written script does, by providing a program for action. Silvan Tomkins created script theory as a further development of his affect theory, which regards human beings' emotional responses to stimuli as falling into categories called affects: he noticed that the purely biological response of affect may be followed by awareness and by what we cognitively do in terms of acting on that affect, so that more was needed to produce a complete explanation of what he called human being theory. These scripts fall under the larger cognitive concept called schemas, which are organized chunks of information. A schema is a script that has the potential to lack the specificity of the sequence of events. A schema becomes a script is when there is an ordering to it that requires action, such as the process of starting a car (get in, put on the seatbelt, turn the car on, release the emergency brake, etc.). In script theory, the basic unit of analysis is called a scene, defined as a sequence of events linked by the affects triggered during the experience of those events. Tomkins recognized that affective experiences fall into patterns that we may group together according to criteria, such as the types of persons and places involved and the degree of intensity of the effect experienced—the patterns of which constitute scripts that inform behavior in an effort to maximize positive affect and to minimize negative affect. == In artificial intelligence == Roger Schank, Robert P. Abelson and their research group extended Tomkins' scripts and used them in early artificial intelligence work as a method of representing procedural knowledge. In their work, scripts are very much like frames, except the values that fill the slots must be ordered. A script is a structured representation describing a stereotyped sequence of events in a particular context. Scripts are used in natural-language understanding systems to organize a knowledge base in terms of the situations that the system should understand. The classic example of a script involves the typical sequence of events that occur when a person drinks in a restaurant: finding a seat, reading the menu, ordering drinks from the waitstaff, etc. In the script form, these would be decomposed into conceptual transitions, such as MTRANS and PTRANS, which refer to mental transitions [of information] and physical transitions [of things]. Schank, Abelson and their colleagues tackled some of the most difficult problems in artificial intelligence (i.e., story understanding), but ultimately their line of work ended without tangible success. This type of work received little attention after the 1980s, but became very influential in later knowledge representation techniques, such as case-based reasoning. Scripts can be inflexible. To deal with inflexibility, smaller modules called memory organization packets (MOP) can be combined in a way that is appropriate for the situation.

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  • Semantic knowledge management

    Semantic knowledge management

    In computer science, semantic knowledge management is a set of practices that seeks to classify content so that the knowledge it contains may be immediately accessed and transformed for delivery to the desired audience, in the required format. This classification of content is semantic in its nature – identifying content by its type or meaning within the content itself and via external, descriptive metadata – and is achieved by employing XML technologies. The specific outcomes of these practices are: Maintain content for multiple audiences together in a single document Transform content into various delivery formats without re-authoring Search for content more effectively Involve more subject-matter experts in the creation of content without reducing quality Reduce production costs for delivery formats Reduce the manual administration of getting the right knowledge to the right people Reduce the cost and time to localize content == Notable semantic knowledge management systems == Learn eXact Thinking Cap LCMS Thinking Cap LMS Xyleme LCMS iMapping

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  • Voice user interface

    Voice user interface

    A voice user interface (VUI) enables spoken human interaction with computers, using speech recognition to understand spoken commands and answer questions, and typically text to speech to play a reply. A voice command device is a device controlled with a voice user interface. Voice user interfaces have been added to automobiles, home automation systems, computer operating systems, home appliances like washing machines and microwave ovens, and television remote controls. They are the primary way of interacting with virtual assistants on smartphones and smart speakers. Older automated attendants (which route phone calls to the correct extension) and interactive voice response systems (which conduct more complicated transactions over the phone) can respond to the pressing of keypad buttons via DTMF tones, but those with a full voice user interface allow callers to speak requests and responses without having to press any buttons. Newer voice command devices are speaker-independent, so they can respond to multiple voices, regardless of accent or dialectal influences. They are also capable of responding to several commands at once, separating vocal messages, and providing appropriate feedback, accurately imitating a natural conversation. == Overview == A VUI is the interface to any speech application. Only a short time ago, controlling a machine by simply talking to it was only possible in science fiction. Until recently, this area was considered to be artificial intelligence. However, advances in technologies like text-to-speech, speech-to-text, natural language processing, and cloud services contributed to the mass adoption of these types of interfaces. VUIs have become more commonplace, and people are taking advantage of the value that these hands-free, eyes-free interfaces provide in many situations. VUIs rely on the ability to process input reliably, inconsistent performance often leads to decreased user engagement and negative feedback. Designing a good VUI requires interdisciplinary talents of computer science, linguistics and human factors such as psychology. Even with advanced development tools, constructing an effective VUI requires understanding of both the tasks to be performed, as well as the target audience that will use the final system. The closer the VUI matches the user's mental model of the task, the easier it will be to use with little or no training, resulting in both higher efficiency and higher user satisfaction. A VUI designed for the general public should emphasize ease of use and provide a lot of help and guidance for first-time callers. In contrast, a VUI designed for a small group of power users (including field service workers), should focus more on productivity and less on help and guidance. Such applications should streamline the call flows, minimize prompts, eliminate unnecessary iterations and allow elaborate "mixed initiative dialogs", which enable callers to enter several pieces of information in a single utterance and in any order or combination. In short, speech applications have to be carefully crafted for the specific business process that is being automated. Not all business processes render themselves equally well for speech automation. In general, the more complex the inquiries and transactions are, the more challenging they will be to automate, and the more likely they will be to fail with the general public. In some scenarios, automation is simply not applicable, so live agent assistance is the only option. A legal advice hotline, for example, would be very difficult to automate. On the flip side, speech is perfect for handling quick and routine transactions, like changing the status of a work order, completing a time or expense entry, or transferring funds between accounts. == History == Early applications for VUI included voice-activated dialing of phones, either directly or through a (typically Bluetooth) headset or vehicle audio system. In 2007, a CNN business article reported that voice command was over a billion dollar industry and that companies like Google and Apple were trying to create speech recognition features. In the years since the article was published, the world has witnessed a variety of voice command devices. Additionally, Google has created a speech recognition engine called Pico TTS and Apple released Siri. Voice command devices are becoming more widely available, and innovative ways for using the human voice are always being created. For example, Business Week suggests that the future remote controller is going to be the human voice. Currently Xbox Live allows such features and Jobs hinted at such a feature on the new Apple TV. == Voice command software products on computing devices == Both Apple Mac and Windows PC provide built in speech recognition features for their latest operating systems. === Microsoft Windows === Two Microsoft operating systems, Windows 7 and Windows Vista, provide speech recognition capabilities. Microsoft integrated voice commands into their operating systems to provide a mechanism for people who want to limit their use of the mouse and keyboard, but still want to maintain or increase their overall productivity. ==== Windows Vista ==== With Windows Vista voice control, a user may dictate documents and emails in mainstream applications, start and switch between applications, control the operating system, format documents, save documents, edit files, efficiently correct errors, and fill out forms on the Web. The speech recognition software learns automatically every time a user uses it, and speech recognition is available in English (U.S.), English (U.K.), German (Germany), French (France), Spanish (Spain), Japanese, Chinese (Traditional), and Chinese (Simplified). In addition, the software comes with an interactive tutorial, which can be used to train both the user and the speech recognition engine. ==== Windows 7 ==== In addition to all the features provided in Windows Vista, Windows 7 provides a wizard for setting up the microphone and a tutorial on how to use the feature. ==== Mac OS X ==== All Mac OS X computers come pre-installed with the speech recognition software. The software is user-independent, and it allows for a user to, "navigate menus and enter keyboard shortcuts; speak checkbox names, radio button names, list items, and button names; and open, close, control, and switch among applications." However, the Apple website recommends a user buy a commercial product called Dictate. === Commercial products === If a user is not satisfied with the built in speech recognition software or a user does not have a built speech recognition software for their OS, then a user may experiment with a commercial product such as Braina Pro or DragonNaturallySpeaking for Windows PCs, and Dictate, the name of the same software for Mac OS. == Voice command mobile devices == Any mobile device running Android OS, Microsoft Windows Phone, iOS 9 or later, or Blackberry OS provides voice command capabilities. In addition to the built-in speech recognition software for each mobile phone's operating system, a user may download third party voice command applications from each operating system's application store: Apple App store, Google Play, Windows Phone Marketplace (initially Windows Marketplace for Mobile), or BlackBerry App World. === Android OS === Google has developed an open source operating system called Android, which allows a user to perform voice commands such as: send text messages, listen to music, get directions, call businesses, call contacts, send email, view a map, go to websites, write a note, and search Google. The speech recognition software is available for all devices since Android 2.2 "Froyo", but the settings must be set to English. Google allows for the user to change the language, and the user is prompted when he or she first uses the speech recognition feature if he or she would like their voice data to be attached to their Google account. If a user decides to opt into this service, it allows Google to train the software to the user's voice. Google introduced the Google Assistant with Android 7.0 "Nougat". It is much more advanced than the older version. Amazon.com has the Echo that uses Amazon's custom version of Android to provide a voice interface. === Microsoft Windows === Windows Phone is Microsoft's mobile device's operating system. On Windows Phone 7.5, the speech app is user independent and can be used to: call someone from your contact list, call any phone number, redial the last number, send a text message, call your voice mail, open an application, read appointments, query phone status, and search the web. In addition, speech can also be used during a phone call, and the following actions are possible during a phone call: press a number, turn the speaker phone on, or call someone, which puts the current call on hold. Windows 10 introduces Cortana, a voice control system that replaces the formerly used voice control on Windows

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  • Daniel Wolfe

    Daniel Wolfe

    Daniel Wolfe (born 1960) is an American activist, advocate, and writer whose work advances health programs and policy that balance scientific research and community expertise. His career has focused on support for community health movements, particularly among groups often regarded as criminal or socially suspect, including gay men and people who use illicit drugs. == Early life == Wolfe was raised between Arizona—including time on Rancho Linda Vista, a commune outside of Tucson—and East Hampton, NY. He received his undergraduate degree in Near Eastern Studies from Princeton University, and following time studying Arabic in Egypt, worked as the junior ghostwriter on the autobiographies of First Lady of Egypt Jehan Sadat and Pakistani Prime Minister Benazir Bhutto. Upon return to New York, he was an assistant at the Council on Foreign Relations to Richard W. Murphy, former US Assistant Secretary of State for Near Eastern and South Asian Affairs. Disagreement with US killing of Iraqi civilians during the 1990 Gulf War—and the rising toll of HIV in NY—moved Wolfe to leave Middle East studies and work full-time on AIDS in 1990. == Education == Wolfe was Community Scholar at the Columbia University Mailman School of Public Healthwhere he received his Masters in Public Health in 2004. He holds a Masters of Philosophy (in history) from Columbia University, and a BA in Near Eastern Studies from Princeton University. He was the recipient of a Charles H. Revson Foundation fellowship for urban leaders who have made a substantial contribution to New York City, and a fellow at the Center for Arabic Studies Abroad in Cairo, Egypt. == AIDS and gay activism == Wolfe was part of the media committee for ACT UP’s 1998 action to seize control of the FDA, and helped organize ACT UP NY’s challenge to Governor Cuomo to do better on the AIDS response and other actions.Wolfe also joined ACT UP colleagues Gregg Bordowitz, David Barr, Richard Elovich, Jean Carlomusto and others to work at Gay Men’s Health Crisis (GMHC), the nation’s first AIDS organization, where he served as director of communications and spokesperson on issues including opposition to NY State cuts to the AIDS budget, the disclosure that Olympic Champion Greg Louganis had HIV, reports of the FBI spying on AIDS activists, and GMHC’s move to offer HIV testing and targeted support to those who were HIV-negative. Wolfe also continued cultural work, making art, performance and video as a member of the gay and lesbian collective GANG with artists and ACT UP members including Zoe Leonard, Suzanne Wright, Loring McAlpin, Wellington Love, Adam Rolston and others, and writing a biography of Lawrence of Arabia for a series for young adults on famous gay men and lesbians in history edited by Martin Duberman. Controversy followed, with North Carolina Senator Jesse Helms waving a GANG piece in an issue of the Movement Research Performance Journal on the floor of Congress to show the "rottenness" of publicly funded art, and a number of schools banning the biography series for young adults from their libraries. Wolfe and others challenged the move as continuing the longstanding and homophobic demand that notable gay men and lesbians stay silent about essential details of their private lives even while being celebrated for their professional achievements. == Gay health == The approval of antiretroviral therapy for HIV in 1996 opened up new space for discussions of gay health beyond HIV, and new directions for Wolfe. Working from hundreds of interviews, surveys, workshops, and with a team of writers, Wolfe was the author of Men Like Us, the Our Bodies, Ourselves-inspired GMHC Complete Guide to Gay Men’s Sexual, Physical, and Emotional Well-being, covering issues from spirituality to sexual health to aging. The move to frame gay health beyond condoms and pills—and to offer a guide to health that “did not need to be translated from the original heterosexual”—was part of a larger gay health movement encompassing wellness and pleasure, and focused less on health disparity than on individual and community resilience. Wolfe was a keynote speaker and workshop leader, along with Eric Rofes, Chris Bartlett, and other organizers, at the first National Gay Men’s Health Summit held in Boulder, Colorado in 2002. Awarded a Charles H. Revson Fellowship for urban leaders in the City of New York, Wolfe became a community scholar at Columbia University’s Center of History and Ethics of Public Health, where he received his MPH in 2003, and was a contributor to Searching Eyes: Privacy, the State, and Disease Surveillance in America. == International harm reduction == Wolfe was Director of International Harm Reduction Development at the Open Society Foundations (2005-2021) where he led grantmaking and advocacy to protect the health and rights of people who use drugs in Eastern Europe, Asia, Africa and the Americas. Wolfe challenged approaches that conditioned support on abstinence or that sought to treat people who use illegal drugs like drugs themselves, as something to be controlled or contained. As with the gay health movement, he advocated a focus on community resilience and strengths, and on supporting individuals and communities to negotiate the balance between risk and pleasure of activities integral to life. Noting what he called the “antisocial behavior of health systems,” Wolfe’s analysis elevated issues such as forced labor and harsh punishment delivered in the name of addiction treatment and rehabilitation, the role of criminalization, imprisonment and stigma in interrupting or impeding HIV treatment, and the bias toward coercive approaches in studying and delivering addiction treatments. He also pointed to defects in national and international drug control policies and human rights violations as a root cause of HIV, hepatitis, and other health challenges faced by people who used drugs. Concrete advocacy supported by Open Society’s International Harm Reduction Development program under his direction included rebuffing US government efforts to force the UN to remove all references to harm reduction in its materials, addition of the addiction treatment medicines methadone and buprenorphine to the World Health Organization’s essential medicines list, and WHO endorsement of lay distribution of the opioid overdose antidote naloxone. Wolfe and OSF colleagues also advocated for new approaches to intellectual property and data sharing in research and development of medicines and vaccines to lower price and improve access to medicines globally to those in need. == AI and patient rights == Reports of patients denied opioid prescriptions based on an algorithm purporting to calculate their risk of overdose led Wolfe to work on AI, first as a resident at the Rockefeller Foundation Bellagio Center, and then as Executive Director of a new UCSF UC Berkeley program pioneering efforts to join AI, clinical and public health practice, and equity. In keeping with his earlier (analog) work on HIV, Wolfe has highlighted concerns about health systems using algorithms to gauge the merit of treatments for those regarded as socially suspect, the importance of moving beyond proprietary, black box algorithms toward an architecture of health data as a public good, and the need to maximize benefit for patients and communities, as well health systems, in the use of large language models.

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  • Jan Leike

    Jan Leike

    Jan Leike (born 1986 or 1987) is an AI alignment researcher who has worked at DeepMind and OpenAI. He joined Anthropic in May 2024. == Education == Jan Leike obtained his undergraduate degree from the University of Freiburg in Germany. After earning a master's degree in computer science, he pursued a PhD in machine learning at the Australian National University under the supervision of Marcus Hutter. == Career == Leike made a six-month postdoctoral fellowship at the Future of Humanity Institute before joining DeepMind to focus on empirical AI safety research, where he collaborated with Shane Legg. === OpenAI === In 2021, Leike joined OpenAI. In June 2023, he and Ilya Sutskever became the co-leaders of the newly introduced "superalignment" project, which aimed to determine how to align future artificial superintelligences within four years to ensure their safety. This project involved automating AI alignment research using relatively advanced AI systems. At the time, Sutskever was OpenAI's Chief Scientist, and Leike was the Head of Alignment. Leike was featured in Time's list of the 100 most influential personalities in AI, both in 2023 and in 2024. In May 2024, Leike announced his resignation from OpenAI, following the departure of Sutskever, Daniel Kokotajlo and several other AI safety employees from the company. Leike wrote that "Over the past years, safety culture and processes have taken a backseat to shiny products", and that he "gradually lost trust" in OpenAI's leadership. In May 2024, Leike joined Anthropic, an AI company founded by former OpenAI employees.

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