GLIMMER

GLIMMER

In bioinformatics, GLIMMER (Gene Locator and Interpolated Markov ModelER) is used to find genes in prokaryotic DNA. "It is effective at finding genes in bacteria, archea, viruses, typically finding 98-99% of all relatively long protein coding genes". GLIMMER was the first system that used the interpolated Markov model to identify coding regions. The GLIMMER software is open source and is maintained by Steven Salzberg, Art Delcher, and their colleagues at the Center for Computational Biology at Johns Hopkins University. The original GLIMMER algorithms and software were designed by Art Delcher, Simon Kasif and Steven Salzberg and applied to bacterial genome annotation in collaboration with Owen White. == Versions == === GLIMMER 1.0 === First Version of GLIMMER "i.e., GLIMMER 1.0" was released in 1998 and it was published in the paper Microbial gene identification using interpolated Markov model. Markov models were used to identify microbial genes in GLIMMER 1.0. GLIMMER considers the local composition sequence dependencies which makes GLIMMER more flexible and more powerful when compared to fixed-order Markov model. There was a comparison made between interpolated Markov model used by GLIMMER and fifth order Markov model in the paper Microbial gene identification using interpolated Markov models. "GLIMMER algorithm found 1680 genes out of 1717 annotated genes in Haemophilus influenzae where fifth order Markov model found 1574 genes. GLIMMER found 209 additional genes which were not included in 1717 annotated genes where fifth order Markov model found 104 genes."' === GLIMMER 2.0 === Second Version of GLIMMER i.e., GLIMMER 2.0 was released in 1999 and it was published in the paper Improved microbial identification with GLIMMER. This paper provides significant technical improvements such as using interpolated context model instead of interpolated Markov model and resolving overlapping genes which improves the accuracy of GLIMMER. Interpolated context models are used instead of interpolated Markov model which gives the flexibility to select any base. In interpolated Markov model probability distribution of a base is determined from the immediate preceding bases. If the immediate preceding base is irrelevant amino acid translation, interpolated Markov model still considers the preceding base to determine the probability of given base where as interpolated context model which was used in GLIMMER 2.0 can ignore irrelevant bases. False positive predictions were increased in GLIMMER 2.0 to reduce the number of false negative predictions. Overlapped genes are also resolved in GLIMMER 2.0. Various comparisons between GLIMMER 1.0 and GLIMMER 2.0 were made in the paper Improved microbial identification with GLIMMER which shows improvement in the later version. "Sensitivity of GLIMMER 1.0 ranges from 98.4 to 99.7% with an average of 99.1% where as GLIMMER 2.0 has a sensitivity range from 98.6 to 99.8% with an average of 99.3%. GLIMMER 2.0 is very effective in finding genes of high density. The parasite Trypanosoma brucei, responsible for causing African sleeping sickness is being identified by GLIMMER 2.0" === GLIMMER 3.0 === Third version of GLIMMER, "GLIMMER 3.0" was released in 2007 and it was published in the paper Identifying bacterial genes and endosymbiont DNA with Glimmer. This paper describes several major changes made to the GLIMMER system including improved methods to identify coding regions and start codon. Scoring of ORF in GLIMMER 3.0 is done in reverse order i.e., starting from stop codon and moves back towards the start codon. Reverse scanning helps in identifying the coding portion of the gene more accurately which is contained in the context window of IMM. GLIMMER 3.0 also improves the generated training set data by comparing the long-ORF with universal amino acid distribution of widely disparate bacterial genomes."GLIMMER 3.0 has an average long-ORF output of 57% for various organisms where as GLIMMER 2.0 has an average long-ORF output of 39%." GLIMMER 3.0 reduces the rate of false positive predictions which were increased in GLIMMER 2.0 to reduce the number of false negative predictions. "GLIMMER 3.0 has a start-site prediction accuracy of 99.5% for 3'5' matches where as GLIMMER 2.0 has 99.1% for 3'5' matches. GLIMMER 3.0 uses a new algorithm for scanning coding regions, a new start site detection module, and architecture which integrates all gene predictions across an entire genome." Minimum description length === Theoretical and Biological Foundation === The GLIMMER project helped introduce and popularize the use of variable length models in Computational Biology and Bioinformatics that subsequently have been applied to numerous problems such as protein classification and others. Variable length modeling was originally pioneered by information theorists and subsequently ingeniously applied and popularized in data compression (e.g. Ziv-Lempel compression). Prediction and compression are intimately linked using Minimum Description Length Principles. The basic idea is to create a dictionary of frequent words (motifs in biological sequences). The intuition is that the frequently occurring motifs are likely to be most predictive and informative. In GLIMMER the interpolated model is a mixture model of the probabilities of these relatively common motifs. Similarly to the development of HMMs in Computational Biology, the authors of GLIMMER were conceptually influenced by the previous application of another variant of interpolated Markov models to speech recognition by researchers such as Fred Jelinek (IBM) and Eric Ristad (Princeton). The learning algorithm in GLIMMER is different from these earlier approaches. == Access == GLIMMER can be downloaded from The Glimmer home page (requires a C++ compiler). Alternatively, an online version is hosted by NCBI [1]. == How it works == GLIMMER primarily searches for long-ORFS. An open reading frame might overlap with any other open reading frame which will be resolved using the technique described in the sub section. Using these long-ORFS and following certain amino acid distribution GLIMMER generates training set data. Using these training data, GLIMMER trains all the six Markov models of coding DNA from zero to eight order and also train the model for noncoding DNA GLIMMER tries to calculate the probabilities from the data. Based on the number of observations, GLIMMER determines whether to use fixed order Markov model or interpolated Markov model. If the number of observations are greater than 400, GLIMMER uses fixed order Markov model to obtain there probabilities. If the number of observations are less than 400, GLIMMER uses interpolated Markov model which is briefly explained in the next sub section. GLIMMER obtains score for every long-ORF generated using all the six coding DNA models and also using non-coding DNA model. If the score obtained in the previous step is greater than a certain threshold then GLIMMER predicts it to be a gene. The steps explained above describes the basic functionality of GLIMMER. There are various improvements made to GLIMMER and some of them are described in the following sub-sections. === The GLIMMER system === GLIMMER system consists of two programs. First program called build-imm, which takes an input set of sequences and outputs the interpolated Markov model as follows. The probability for each base i.e., A,C,G,T for all k-mers for 0 ≤ k ≤ 8 is computed. Then, for each k-mer, GLIMMER computes weight. New sequence probability is computed as follows. where n is the length of the sequence S x {\displaystyle S_{x}} is the oligomer at position x. I M M 8 ( S x ) {\displaystyle IMM_{8}(S_{x})} , the 8 t h {\displaystyle 8^{th}} -order interpolated Markov model score is computed as "where Y k ( S x − 1 ) {\displaystyle Y_{k}(S_{x-1})} is the weight of the k-mer at position x-1 in the sequence S and P k ( S x ) {\displaystyle P_{k}(S_{x})} is the estimate obtained from the training data of the probability of the base located at position x in the k t h {\displaystyle k^{th}} -order model." The probability of base S x {\displaystyle S_{x}} given the i previous bases is computed as follows. "The value of Y i ( S x ) {\displaystyle Y_{i}(S_{x})} associated with P i ( S x ) {\displaystyle P_{i}(S_{x})} can be regarded as a measure of confidence in the accuracy of this value as an estimate of the true probability. GLIMMER uses two criteria to determine Y i ( S x ) {\displaystyle Y_{i}(S_{x})} . The first of these is simple frequency occurrence in which the number of occurrences of context string S x , i {\displaystyle S_{x,i}} in the training data exceeds a specific threshold value, then Y i ( S x ) {\displaystyle Y_{i}(S_{x})} is set to 1.0. The current default value for threshold is 400, which gives 95% confidence. When there are insufficient sample occurrences of a context string, build-imm employ additional criteria to determine Y {\displaystyle Y} value. For a

Altibase

Altibase is a hybrid database, relational database management system manufactured by the Altibase Corporation. The software's hybrid architecture allows it to access both memory-resident and disk-resident tables using single interface. It supports both synchronous and asynchronous replication and offers real-time ACID compliance. Support is also offered for a variety of SQL standards and programming languages. Other important capabilities include data import and export, data encryption for security, multiple data access command sets, materialized view and temporary tables, and others. == History == From 1991 through 1997 the Mr. RT project was an in-memory database research project, conducted by the Electronics and Telecommunications Research Institute a government-funded research organization in South Korea. Altibase was incorporated in 1999. Altibase acquired an in-memory database engine from the Electronics and Telecommunications Research Institute in February 2000, and commercialized the database in October of the same year. In 2001, Altibase changed the name of the in-memory database product from "Spiner" to "Altibase" in 2001. In 2004, Altibase integrated the in-memory database with a disk-resident database to create a hybrid DBMS, released version 4.0 and renamed it as ALTIBASE HDB. Altibase released version 5.5.1 and 6.1.1 in 2012, version 6.3.1 in November 2013, and 6.5.1 in May 2015. Altibase claims that this is the world's first hybrid DBMS. Altibase released its open source edition version 7.1, however, closed the source in 2023. In August 2023, Altibase released its cloud-optimized version 7.3. === Awards === In 2006, Received the Presidential Award at the Korea Software Awards In 2007, Selected as World-Class Product by the Ministry of Commerce, Industry and Energy In 2009, Awarded the Outstanding Product Award in China's Telecommunications Industry In 2009, Received Outstanding Product Award at the China Billing China 2009 Telecommunication Industry Awards In 2010, Commendation from the Minister of Knowledge Economy for Technological Practicalization In 2011, Received the Grand Prize at the 10th Software Enterprise Competitiveness Award In 2011, Selected as Top 10 Emerging Technologies and received Special Award at the Korea Technology Grand Prize In 2012, Awarded for Contributions to Military Manpower Administration In 2014~2016, Included in Gartner Magic Quadrant for Operational DBMS In 2015, Selected as Outstanding BSS by China Fujian Mobile. In 2023, Awarded as the Excellent Research and Development Institution by the Korean Ministry Science and ICT In 2023, Won the Global Premium Commercial Software Presidential Award at the 9th Global Commercial Software Grand Exhibition in Korea === Release === The first version, called Spiner, was released in 2000 for commercial use. It took half of the in-memory DBMS market share in South Korea. In 2002 the second version was released renamed to Altibase v2.0. By 2003, Altibase v3.0 was released and it entered the Chinese market. Released version 4.0 with hybrid architecture, combining RAM and disk databases, was released in 2004. In 2005 Altibase began working with Chinese telecommunications providers for billing systems, and some financial companies in Taiwan, China, for home trading systems. The software was certified by the Telecommunications Technology Association. The Ministry of Government Administration and Home Affairs gave it an award in 2006. Offices in China and United States opened in 2009. In 2011, version 5.5.1 was renamed it to HDB (for "hybrid database"). The Altibase Data Stream product for complex event processing was renamed DSM. The product received a Korean technology award. Altibase introduced certification services. In 2012, HDB Zeta and Extreme were announced, and DSM renamed to CEP. In 2013, yet another variant called XDB was announced, and the company received ISO/IEC 20000 certification. In 2018, Altibase went open source. Altibase went open source in February, 2018. Altibase Corp has made the decision to discontinue the Altibase 7.1 open source edition, effective March 17, 2023. As a result, the open-source edition of Altibase 7.1 will no longer be available for download or use. Altibase released version 7.3 in September, 2023, its notable feature is the world’s first hybrid partition, allowing data to be stored in both memory and on disk at the partition level. Version 7.3 also added parallel processing capabilities for high-speed performance in both partitioned and non-partitioned scenarios. Improving potential bottlenecks associated with Commit and logging that impact transaction performance, version 7.3 has achieved an approximately 490% enhancement in performance compared to previous versions. === Release history === == Clients == According to marketing research, Altibase have over 700 customers and more than 8,000 of installations and deployments, including 22 Fortune Global 500 Companies. Altibase's clients in the telecommunications, financial services, manufacturing, and utilities sectors include Bloomberg, AT&T, LG, Intel, LGU+, ETRADE, HP, UAT Inc., POSCO, SK Telecom, KT Corporation, Samsung Electronics, Shinhan Bank, Woori Bank, Canon(Toshiba), Hanhwa, The South Korean Ministry of Defense, G-Market, CJ, and Chung-Ang University. === Global clients === Japan FX Prime, a foreign exchange services company Retela Crea Securities United States AT&T Implemented Altibase for its PS-LTE Safety network, where the Presence service plays a vital role. This service handles the reception and storage of user information, conducting real-time checks for online presence and location as needed. Canada Telus One of the major telecommunication companies. Utilizes Altibase for its operations involving real-time user management, processing high volumes of dedicated terminal data, and managing real-time location information (GIS) for terminals. Altibase contributes to the company's in-house solution for maintaining uninterrupted services during national disasters or similar situations, ensuring efficiency and reliability. China China Mobile, China Unicom, China Telecom The three major telecommunications companies. Utilize ALTIBASE HDB in 29 of 31 Chinese provinces. Turkish Ziraat Bank, Halk Bank, Deniz Bank, Garanti BBVA, TEB, Oyak Bank, QNB, Burgan Bank, and others. In 2018, Altibase entered the market through a partnership with ATP-Tradesoft, a subsidiary of Ata Holdings. Collaborating with ATP-Tradesoft. Altibase integrated into the Online Trading System XFront. This integration was well-received by major financial institutions and securities firms in Turkey. Altibase is currently implemented in the XFront Online Trading System, used by 13 significant financial institutions and banks in the Turkey. Thailand Bualuang Securities Altibase has been supplied its DBMS to support the construction of the online stock trading platform. Mongolia MobiCom The Mongolian telecommunication giant, has adopted Altibase’s 7.0 version for its mobile platform for storing the infrequently used data. Azerbaijan M1 highway Altibase has been supplied as the Database Management System (DBMS) for the electronic toll collection system. One of the most crucial transportation networks in the country. India State-owned Karur Vysya Bank In 2013, Altibase provided its hybrid database solution and was deployed for the online banking system === Industries === Telecommunications LGU+ SK Telecom KT Corporation AT&T Telus Financial services Shinhan Bank Woori Bank KakaoPay Securities Implemented Altibase in its stock trading system Leveraging Altibase's replication feature, along with offline replication through shared disk and adapter functionality, the system ensures a high level of availability and consistency, with a reliability rate of 99.999% even in the event of system failures. COREDAX Cryptocurrency market Altibase has entered into a strategic partnership by signing a database management system (DBMS) supply contract with the cryptocurrency exchange Bloomberg ETRADE Manufacturing Samsung Electronics LG POSCO Hanhwa Canon(Toshiba) Intel HP Utilities South Korean Ministry of Defense G-Market CJ UAT Inc. Chung-Ang University == Features == Altibase is a so-called "hybrid DBMS", meaning that it simultaneously supports access to both memory-resident and disk-resident tables via a single interface. It is compatible with Solaris, HP-UX, AIX, Linux, and Windows. It supports the complete SQL standard, features Multiversion concurrency control (MVCC), implements Fuzzy and Ping-Pong Checkpointing for periodically backing up memory-resident data, and ships with Replication and Database Link functionality. High performance, large -capacity service Fast real-time data processing and large amounts of data stable Provide parallel processing architecture for large data management Developed and provided Hybrid Partitioned Table function for efficiency according to data personality High stability

Spectral shape analysis

Spectral shape analysis relies on the spectrum (eigenvalues and/or eigenfunctions) of the Laplace–Beltrami operator to compare and analyze geometric shapes. Since the spectrum of the Laplace–Beltrami operator is invariant under isometries, it is well suited for the analysis or retrieval of non-rigid shapes, i.e. bendable objects such as humans, animals, plants, etc. == Laplace == The Laplace–Beltrami operator is involved in many important differential equations, such as the heat equation and the wave equation. It can be defined on a Riemannian manifold as the divergence of the gradient of a real-valued function f: Δ f := div ⁡ grad ⁡ f . {\displaystyle \Delta f:=\operatorname {div} \operatorname {grad} f.} Its spectral components can be computed by solving the Helmholtz equation (or Laplacian eigenvalue problem): Δ φ i + λ i φ i = 0. {\displaystyle \Delta \varphi _{i}+\lambda _{i}\varphi _{i}=0.} The solutions are the eigenfunctions φ i {\displaystyle \varphi _{i}} (modes) and corresponding eigenvalues λ i {\displaystyle \lambda _{i}} , representing a diverging sequence of positive real numbers. The first eigenvalue is zero for closed domains or when using the Neumann boundary condition. For some shapes, the spectrum can be computed analytically (e.g. rectangle, flat torus, cylinder, disk or sphere). For the sphere, for example, the eigenfunctions are the spherical harmonics. The most important properties of the eigenvalues and eigenfunctions are that they are isometry invariants. In other words, if the shape is not stretched (e.g. a sheet of paper bent into the third dimension), the spectral values will not change. Bendable objects, like animals, plants and humans, can move into different body postures with only minimal stretching at the joints. The resulting shapes are called near-isometric and can be compared using spectral shape analysis. == Discretizations == Geometric shapes are often represented as 2D curved surfaces, 2D surface meshes (usually triangle meshes) or 3D solid objects (e.g. using voxels or tetrahedra meshes). The Helmholtz equation can be solved for all these cases. If a boundary exists, e.g. a square, or the volume of any 3D geometric shape, boundary conditions need to be specified. Several discretizations of the Laplace operator exist (see Discrete Laplace operator) for the different types of geometry representations. Many of these operators do not approximate well the underlying continuous operator. == Spectral shape descriptors == === ShapeDNA and its variants === The ShapeDNA is one of the first spectral shape descriptors. It is the normalized beginning sequence of the eigenvalues of the Laplace–Beltrami operator. Its main advantages are the simple representation (a vector of numbers) and comparison, scale invariance, and in spite of its simplicity a very good performance for shape retrieval of non-rigid shapes. Competitors of shapeDNA include singular values of Geodesic Distance Matrix (SD-GDM) and Reduced BiHarmonic Distance Matrix (R-BiHDM). However, the eigenvalues are global descriptors, therefore the shapeDNA and other global spectral descriptors cannot be used for local or partial shape analysis. === Global point signature (GPS) === The global point signature at a point x {\displaystyle x} is a vector of scaled eigenfunctions of the Laplace–Beltrami operator computed at x {\displaystyle x} (i.e. the spectral embedding of the shape). The GPS is a global feature in the sense that it cannot be used for partial shape matching. === Heat kernel signature (HKS) === The heat kernel signature makes use of the eigen-decomposition of the heat kernel: h t ( x , y ) = ∑ i = 0 ∞ exp ⁡ ( − λ i t ) φ i ( x ) φ i ( y ) . {\displaystyle h_{t}(x,y)=\sum _{i=0}^{\infty }\exp(-\lambda _{i}t)\varphi _{i}(x)\varphi _{i}(y).} For each point on the surface the diagonal of the heat kernel h t ( x , x ) {\displaystyle h_{t}(x,x)} is sampled at specific time values t j {\displaystyle t_{j}} and yields a local signature that can also be used for partial matching or symmetry detection. === Wave kernel signature (WKS) === The WKS follows a similar idea to the HKS, replacing the heat equation with the Schrödinger wave equation. === Improved wave kernel signature (IWKS) === The IWKS improves the WKS for non-rigid shape retrieval by introducing a new scaling function to the eigenvalues and aggregating a new curvature term. === Spectral graph wavelet signature (SGWS) === SGWS is a local descriptor that is not only isometric invariant, but also compact, easy to compute and combines the advantages of both band-pass and low-pass filters. An important facet of SGWS is the ability to combine the advantages of WKS and HKS into a single signature, while allowing a multiresolution representation of shapes. == Spectral Matching == The spectral decomposition of the graph Laplacian associated with complex shapes (see Discrete Laplace operator) provides eigenfunctions (modes) which are invariant to isometries. Each vertex on the shape could be uniquely represented with a combinations of the eigenmodal values at each point, sometimes called spectral coordinates: s ( x ) = ( φ 1 ( x ) , φ 2 ( x ) , … , φ N ( x ) ) for vertex x . {\displaystyle s(x)=(\varphi _{1}(x),\varphi _{2}(x),\ldots ,\varphi _{N}(x)){\text{ for vertex }}x.} Spectral matching consists of establishing the point correspondences by pairing vertices on different shapes that have the most similar spectral coordinates. Early work focused on sparse correspondences for stereoscopy. Computational efficiency now enables dense correspondences on full meshes, for instance between cortical surfaces. Spectral matching could also be used for complex non-rigid image registration, which is notably difficult when images have very large deformations. Such image registration methods based on spectral eigenmodal values indeed capture global shape characteristics, and contrast with conventional non-rigid image registration methods which are often based on local shape characteristics (e.g., image gradients).

AstroPay

AstroPay is a global digital wallet that provides users with a way to pay, send, and receive money. The app provides online payments, virtual and physical debit cards, peer-to-peer money transfers, and more. == History == AstroPay was founded in Uruguay in 2009 as a payment processing company. Over time, it expanded its services across Latin America, EMEA, and APAC. A significant milestone occurred in 2016, when AstroPay spun off dLocal, focusing on cross-border payments for emerging markets. dLocal became Uruguay's first unicorn and eventually went public through a successful IPO. In 2020, AstroPay spun off its payment processing services into a new entity, D24, to focus on mobile wallet for cross border. Between 2023 and 2024 the Company brought new leadership to guide its transition towards becoming a fully focused global digital multicurrency wallet where users save, send, and spend globally. This shift introduced enhanced features, including loyalty prepaid cards and multicurrency accounts. == Services == AstroPay offers three main products: AstroPay Wallet, AstroPay check-out, and AstroPay Platform. AstroPay Wallet is a digital wallet for consumers, where they have multicurrency accounts, prepaid card and marketplace. With AstroPay check-out, businesses can tap into AstroPay's wallet user base by accepting AstroPay as a payment method in their check-out options. Lastly, AstroPay Platform enables other businesses to use the AstroPay network to launch their own global wallet. == Brand endorsements, partnerships == AstroPay's marketing strategy has included the development of co-branded products with sports teams and other brand. The company sponsored Burnley Football Club during the 2018–19 Premier League season, renewing the partnership for the 2021–22 Premier League season when it became the club's official payment service partner. In August 2021, AstroPay entered into a partnership with the Wolverhampton Wanderers for the 2021-22 Premier League season, and the following year, became the team's shirt sponsor. Later, in September 2021, AstroPay expanded its partnership with Wolverhampton Wanderers, which included becoming the team's official payment partner and later, in 2023, co-launching a co-branded card. Other partnerships include Newcastle United in 2021 in the English Premier League. AstroPay made arrangements to ensure that branding and logo would be visible on the pitch-side LED advertising during Premier League matches. Furthermore, in June 2022, the company renewed it's partnership with Wolverhampton Wanderers for the 2022-23 Premier League season and launched its Wolves debit card in February 2023. Some other notable partnerships include: Universidad de Chile in 2024, Tottenham Hotspurs in 2023-25, and even a collaboration with Lionel Messi across all of Latin America. == Recent developments == AstroPay has refocused its strategy since 2023, pivoting from payment processing to concentrate on its global digital wallet. This move reflects a broader effort to redefine the company's market positioning by emphasizing global user-friendly financial services, while separating its identity from previous operations managed by dLocal and D24.

Office automation

Office automation refers to the varied computer machinery and software used to digitally create, collect, store, manipulate, and relay office information needed for accomplishing basic tasks. Raw data storage, electronic transfer, and the management of electronic business information comprise the basic activities of an office automation system. Office automation helps in optimizing or automating existing office procedures. The backbone of office automation is a local area network, which allows users to transfer data, mail and voice across the network. All office functions, including dictation, typing, filing, copying, fax, telex, microfilm and records management, telephone and telephone switchboard operations, fall into this category. Office automation was a popular term in the 1970s and 1980s as the desktop computer exploded onto the scene. Advantages of office automation include that it can get many tasks accomplished faster, it eliminates the need for a large staff, less storage is required to store data, and multiple people can update data simultaneously in the event of changes in schedule. == Outline == Businesses can easily purchase and stock their wares with the aid of technology. Many of the manual tasks that used to be done by hand can now be done through hand held devices and UPC and SKU coding. In the retail setting, automation also increases choice. Customers can easily process their payments through automated credit card machines and no longer have to wait in line for an employee to process and manually type in the credit card numbers. Office payrolls have been automated, which means no one has to manually cut checks, and those checks that are cut can be printed through computer programs. Direct deposit can be automatically set up and this further reduces the manual process, and most employees who participate in direct deposit often find their paychecks come earlier than if they'd have to wait for their checks to be written and then cleared by the bank. Other ways automation has reduced employee manpower on tasks is automated voice direction. Through the use of prompts, automated phone menus and directed calls, the need for employees to be dedicated to answer the phones has been reduced, and in some cases, eliminated.

ImHex

ImHex is a free cross-platform hex editor available on Windows, macOS, and Linux. ImHex is used by programmers and reverse engineers to view and analyze binary data. == History == The initial release of the project in November 2020, saw significant interest on GitHub. == Features == Features include: Hex editor Custom pattern matching and analysis scripting language Visual, node based data pre-processor Disassembler Running and visualizing of YARA rules Bookmarks Binary data diffing Additional Tools MSVC, Itanium, D and Rust name demangler ASCII table Calculator Base converter File utilities IEEE 754 floating point decoder Division by invariant multiplication calculator TCP/IP client and server Support for: Data importing and exporting ASCII string, Unicode string, numeric, hexadecimal and regular expressions search Byte manipulation File hashing Plug-ins

Ave!Comics

Ave!Comics Production is a privately owned French company editing comics on smartphones, tablets and computers. It was founded in 2008 and it is a subsidiary of Aquafadas, a software development company in digital publishing owned by Kobo Inc. AveComics is a comic book store for digital comic books that can be used on computers, tablets, and smartphones.(iOS, Android) Readers can buy and read comic books, manga and graphic novels in French, English and Spanish. AveComics uses a technology created by Aquafadas for comics transformation, distribution and reading, based around its AVE format. The AveComics application was also a finalist in the BlackBerry Innovation Awards 2009, in the "Entertainment" category. == Company history == Aquafadas, a company working on creative software for Flash, HTML5, photo, and video editing, created the application MyComics to allow the reading of comics on mobile in 2006. This application was made available in 2008, to enable the reading and storing of comics on iPhone and iPod Touch. A reading system adapted to low resolution screens was also available. In October of the same year, the company launched a comics library on both devices, in partnership with the Angoulême International Comics Festival, Fnac and SNCF. This library included the official selection of the festival, and was downloaded over 150 000 times. In December 2008 "The Adventures of Lucky Luke n°3", at Lucky Comics was published on both devices. The comic made a 50 000 € turnover. In April 2009, "Les Blondes" 10th volume was the top-selling comic for 10 months on the AppStore. After, in August 2009, the AveComics application was launched on iPhone, iPod Touch and BlackBerry. The company's website was launched in September when more than 100 titles were available on smartphones and computers. == Catalogue == AveComics works with over 80 international publishers including Glénat, Marsu Productions, Delcourt, Casterman, Soleil, Ubisoft, Les Humanoïdes Associés and Mad Fabrik. Comics such as "Assassin's Creed", "Talisman", "Titeuf", and "Seoul District" are sold by the company. == Award == Grand Prix Software Venture Capital - Senate 2008.